Protein peptide main body particle structure in natural whole food form that can be used to improve uric acid breakdown

A protein-peptide particle structure with a core of nutrients and a protective layer addresses uric acid accumulation by improving absorption and stability, effectively reducing gout symptoms through enhanced uric acid metabolism.

DE202025104514U1Active Publication Date: 2025-12-04BIOMED HERBAL RES CO LTD
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Patent Information

Application Number
DE202025104514
Authority / Receiving Office
DE · DE
Patent Type
Utility models
Current Assignee / Owner
Filing Date
2025-07-31
Publication Date
2025-12-04
Estimated Expiration
2035-07-31

AI Technical Summary

Technical Problem

Existing solutions fail to effectively address the accumulation of uric acid in the body, leading to conditions like gout, due to disrupted purine metabolism and inadequate excretion, which results in hyperuricemia and joint inflammation.

Method used

A protein-peptide main body particle structure in natural whole food form, comprising a core layer with nutrients like vitamin C, vitamin B5, folic acid, magnesium, zinc, selenium, and boron, combined with protein peptide carriers and freeze-dried fermented noni powder, is designed with an active protective layer to maintain activity and enhance absorption, protected by an acid-resistant layer to withstand gastric conditions.

Benefits of technology

The structure improves uric acid degradation by enhancing absorption and stability, reducing oxidative damage, and promoting excretion, thereby alleviating gout symptoms and maintaining metabolic balance.

✦ Generated by Eureka AI based on patent content.

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Abstract

A protein-peptide main body particle structure in natural whole food form, which can be used to improve uric acid degradation, is a granular main body (01) comprising a core layer (10) and an active protective layer (20), wherein the active protective layer (20) is provided outside the core layer (10) to prevent the external environment from influencing the activity of the core layer (10) and thus to improve the storage stability of the main body (10) and its absorption rate by the human body; wherein the core layer (10) consists of a composite structure in whole food form of nutrients such as vitamin C, vitamin B5, folic acid, magnesium, zinc, selenium, boron in conjunction with protein-peptide carriers and freeze-dried fermented noni powder.
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Description

Field of invention

[0001] The present invention relates to a main body structure and in particular to a protein-peptide main body particle structure in natural whole food form, revealing an innovative structure, which can be used to improve uric acid degradation. State of the art

[0002] Gout (gouty arthritis) is becoming increasingly common in modern society, where people suffer from high levels of stress, consume refined diets, and lead irregular lifestyles. Studies show that approximately 1% to 4% of the adult population suffers from gout, with men being more frequently affected than women. The risk of developing the disease is about six times higher in men than in women. However, a woman's risk of developing gout gradually increases after menopause.

[0003] Gout manifests as redness, swelling, warmth, and pain in the joints. Attacks are often extremely painful, making walking difficult. Clinically, gout is an extremely painful form of arthritis. It is caused by a disrupted purine metabolism in the body, leading to hyperuricemia, which causes sodium urate to accumulate in the joint cavity, resulting in joint swelling and deformities.

[0004] Uric acid is a metabolic product of the body, produced during purine metabolism. Purines are the basic building blocks of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Every cell contains nucleic acids. Purines are produced daily by the metabolism of body cells. Typically, one-third of the uric acid in the body comes from purine-rich foods, while two-thirds are produced through endogenous cellular metabolism.

[0005] The liver metabolizes purines into uric acid, which is then excreted in urine via the kidneys. Normally, the body produces about 750 mg of uric acid daily, of which approximately 500 mg is excreted by the kidneys and the remainder in the stool. If the body produces too much uric acid, or if the kidneys cannot excrete it properly, uric acid accumulates in the body, leading to an excess of uric acid in the blood. If the uric acid level in the blood remains too high for an extended period, crystal salts form, which are deposited in the joint cavity and gradually fill it. This leads to arthritis symptoms such as redness, swelling, warmth, and pain, a condition known as gout.

[0006] Patients with gout often have a history of hyperuricemia, although not every patient with elevated uric acid levels will necessarily develop gout. However, the risk of gout increases significantly with rising uric acid levels in the blood. In adults, a fasting uric acid level above 7.0 mg / dL is considered hyperuricemia.

[0007] Possible causes of hyperuricemia: (1) The body has problems excreting uric acid, and as a result, uric acid easily accumulates in the body, e.g., due to chronic kidney disease, obesity, dehydration, or high blood pressure; (2) The body produces too much uric acid, leading to an increase in uric acid levels, e.g., due to high intake of purine-rich foods (meat, offal, seafood), fructose-rich foods, or excessive alcohol consumption; (3) Constitutional or genetic predisposition. Some people are born with excessive uric acid production or an abnormal uric acid excretion function, leading to high uric acid levels; (4) Patients taking diuretics or immunosuppressant drugs are more likely to experience symptoms of high uric acid levels. Object of the invention

[0008] The main object of the present invention is to provide a protein-peptide main body particle structure in a natural, whole-food form that can be used to improve uric acid metabolism. To achieve the above object, the following technical solutions are used in the present invention: A protein-peptide main body particle structure in natural whole food form, which can be used to improve uric acid degradation, is a granular main body comprising a core layer and an active protective layer, the active protective layer being located outside the core layer to prevent the external environment from affecting the activity of the core layer, thus improving the storage stability of the main body and its absorption rate by the human body.

[0009] The core layer consists of a composite structure in whole food form made from nutrients such as vitamin C, vitamin B5, folic acid, magnesium, zinc, selenium, boron in combination with protein peptide carriers and freeze-dried fermented noni powder.

[0010] In contrast to conventional technology, the innovative and unique design and technical features of the present invention, through the active protective layer serving as a sheath, can significantly extend the durability and maintain the activity by preventing damage caused by the external environment, in order to achieve the commercial applicability of maintaining the activity and functionality of the core layer and increasing its absorption rate and product effectiveness. Brief description of the drawings Fig. 1 shows a sectional view according to a first embodiment of the present invention; Fig. Figure 2 shows a schematic perspective view with partial cross-section according to the first embodiment of the present invention; Fig. Figure 3 shows a sectional view according to a second embodiment of the present invention; Fig. 4 shows a front view according to a third embodiment of the present invention; Fig. Figure 5 shows a perspective view according to a fourth embodiment of the present invention; Fig. Figure 6 shows a perspective view according to a fifth embodiment of the present invention. Detailed description of the exemplary implementations

[0011] The figures show exemplary embodiments of the protein-peptide main body particle structure according to the invention in natural whole-food form, which can be used to improve uric acid metabolism. The following description explains only exemplary embodiments of the invention and is not to be understood as a limitation of the claims.

[0012] It will be directed to the Fig. 1 and Fig. 2. Referenced. The first embodiment of the protein-peptide main body particle structure in natural whole food form, which can be used to improve uric acid degradation, represents a granular main body 01 comprising a core layer 10 and an active protective layer 20, wherein the active protective layer 20 is provided outside the core layer 10 to prevent the external environment from influencing the activity of the core layer 10, and thus to improve the storage stability of the main body 01 and its absorption rate by the human body.

[0013] The core layer 10 consists of a composite structure in whole food form made from nutrients such as vitamin C, vitamin B5, folic acid, magnesium, zinc, selenium, boron in combination with protein peptide carriers and freeze-dried fermented powder from noni.

[0014] The composition of the active protective layer 20 includes proteins such as pea protein, corn protein, yeast protein and potato protein, but is not limited to them.

[0015] The active protective layer 20, which serves as a coating, can significantly extend the durability of the core layer 10 and maintain its activity by preventing damage caused by the external environment, in order to achieve the commercial applicability of maintaining the activity and functionality of the core layer 10 and increasing its absorption rate and product effectiveness.

[0016] Vitamin C is a commonly used nutrient to improve hyperuricemia or gout. Vitamin C acts as an antioxidant and can reduce oxidative damage to cellular DNA and alleviate inflammation. It also increases the efficiency of kidney metabolism, promotes the excretion of uric acid, and prevents its reabsorption in the kidneys.

[0017] Higher serum levels of vitamin C have a positive effect on purine metabolism and contribute to lowering uric acid concentrations. This reduces the risk of monosodium urate crystals being deposited in joint structures and soft tissues. Vitamin C supplementation therefore helps to lower serum uric acid levels and prevent gout.

[0018] Vitamin B5, also known as pantothenic acid, is an essential nutrient for the synthesis of adrenal cortex hormones such as cortisol and cortisone. Cortisol plays a crucial role in the body's stress response by increasing blood pressure and blood glucose levels. Cortisone influences the transport of uric acid in the renal tubules and is positively correlated with uric acid excretion. During periods of stress, it is particularly important to be aware of a potential vitamin B5 deficiency, as the body produces increased amounts of cortisol and adrenaline, which can lead to a relative decrease in cortisone production. Adequate vitamin B5 intake is therefore a significant factor in regulating uric acid levels.

[0019] Folic acid has diverse physiological functions, including supporting blood cell formation, participating in DNA synthesis, reducing homocysteine ​​levels in the body, and preventing cardiovascular disease. For gout patients, it is particularly relevant that folic acid can inhibit the activity of xanthine oxidase, the enzyme responsible for uric acid formation. This inhibits the formation of xanthine and uric acid, thus contributing to a reduction in blood uric acid concentration.

[0020] Magnesium is the fourth most abundant mineral in the human body. A magnesium deficiency can exacerbate chronic inflammation and oxidative stress, which can lead to DNA damage, among other things. Magnesium supports the normal function of the heart, muscles, and nerves, as well as overall metabolism. Adequate magnesium intake is associated with a reduced risk of diabetes, cancer, chronic kidney disease, and cardiovascular disease.

[0021] Studies show that insufficient magnesium intake increases the risk of hyperuricemia. Increased magnesium intake can reduce this risk and has a preventive effect. Maintaining adequate magnesium levels is therefore an effective nutritional strategy for the prevention and treatment of hyperuricemia. Furthermore, it can reduce overall mortality as well as cardiovascular mortality in patients with gout or elevated uric acid levels.

[0022] Zinc is an essential trace element involved in the regulation of pro-inflammatory cytokines, the control of oxidative stress, and the modulation of the immune response. Zinc possesses antioxidant properties and can prevent oxidative damage to cell nuclei, thereby reducing purine production. Zinc deficiency is associated not only with growth disorders, immunodeficiency, and cognitive impairment, but also with an increased risk of hyperuricemia. Research suggests that zinc may play a potential preventive or protective role in the development of hyperuricemia.

[0023] Selenium possesses strong antioxidant properties and is an essential component of the enzyme glutathione peroxidase. Selenium can stimulate leukocyte activity, boost the immune system, and combat free radicals. This helps prevent oxidative damage to cell nuclei and reduce the release of purines from damaged DNA, thereby inhibiting overall purine production.

[0024] Boron is an essential trace element for the human body. It promotes the absorption of calcium, magnesium, potassium, and phosphorus, supports bone health, and helps reduce the occurrence of arthritis. As a critical nutrient for healthy bones and joints, boron also contributes to increased antioxidant capacity, strengthens muscles, and supports cardiovascular health.

[0025] Noni contains bioactive substances such as superoxide dismutase, quercetin, rutin, and scopoletin. Superoxide dismutase inhibits oxidation by free radicals and reduces the formation of acidic metabolic products. Quercetin and rutin inhibit the activity of xanthine oxidase, leading to a reduction in uric acid synthesis. Scopoletin inhibits the reabsorption of uric acid in the renal tubules, increases uric acid excretion, and has anti-inflammatory and analgesic effects.

[0026] As mentioned above, layer 10 can reduce uric acid formation, promote uric acid excretion, and inhibit its reabsorption by kidney cells. This leads to improved uric acid breakdown, prevention of hyperuricemia and gout, and effective maintenance of metabolic balance in the body. Additionally, it increases antioxidant capacity, reduces inflammatory processes, alleviates the discomfort of inflamed joints, protects the joints, and regulates physiological functions and overall health.

[0027] It will be on Fig. 3. Reference is made to the second embodiment and the first embodiment in that an acid-resistant layer 30 is further provided between the core layer 10 and the active protective layer 20 to prevent the core layer 10 from being destroyed by the gastric acid present in the human digestive tract, thereby further improving the absorption rate of the core layer 10 in the human body.

[0028] The composition of the acid-resistant layer 30 includes, but is not limited to, pectin, trehalose, polyunsaturated fatty acids and acidic amino acids.

[0029] Fig. 4, Fig. 5 and Fig.Figure 6 shows the third, fourth, and fifth embodiments, respectively. The third, fourth, and fifth embodiments each comprise a packaging structure 02 and several main bodies 01, as described in embodiments 1 and 2. The main bodies 01 are arranged within the packaging structure 02.

[0030] The present invention thus provides a protein-peptide main body particle structure in natural whole food form, which can be used to improve uric acid degradation. This main body is a granular structure comprising a core layer and an active protective layer. The active protective layer is located outside the core layer to prevent the external environment from affecting the activity of the core layer, thereby improving the storage stability of the main body and its absorption rate by the human body. The core layer consists of a whole food-form composite structure of nutrients such as vitamin C, vitamin B5, folic acid, magnesium, zinc, selenium, and boron in combination with protein-peptide carriers and freeze-dried fermented noni powder.

Claims

[1] A protein-peptide main body particle structure in natural whole food form, which can be used to improve uric acid degradation, is a granular main body (01) comprising a core layer (10) and an active protective layer (20), wherein the active protective layer (20) is provided outside the core layer (10) to prevent the external environment from affecting the activity of the core layer (10) and thus to improve the storage stability of the main body (10) and its absorption rate by the human body; wherein the core layer (10) consists of a composite structure in whole food form of nutrients such as vitamin C, vitamin B5, folic acid, magnesium, zinc, selenium, boron in association with protein-peptide carriers and freeze-dried fermented noni powder. [2] Protein peptide main body particle structure in natural whole food form which can be used to improve uric acid degradation, according to claim 1, wherein the composition of the active protective layer (20) comprises proteins such as pea protein, maize protein, yeast protein and potato protein. [3] Protein peptide main body particle structure in natural whole food form, which can be used to improve uric acid degradation, according to claim 1, wherein an acid-resistant layer (30) is further provided between the core layer (10) and the active protective layer (20) to prevent the core layer (10) from being destroyed by the gastric acid present in the human digestive tract, thereby further improving the absorption rate of the core layer (10) in the human body. [4] Protein peptide main body particle structure in natural whole food form which can be used to improve uric acid degradation, according to claim 3, wherein the composition of the acid-resistant layer (30) comprises pectin, trehalose, polyunsaturated fatty acids and acidic amino acids.