SYSTEM FOR MONITORING SUBSTANCE INTAKE

Description

[0001] The invention relates to a system for monitoring the intake of substances, in particular pharmaceutical substances or nicotine.

[0002] There are many ways to introduce active substances into the body, in particular oral or nasal administration in the form of a liquid, for example in drop form or in the form of a spray, but also in the form of tablets or chewing gums that release their active ingredient in the mouth or stomach of the user after oral ingestion.

[0003] Furthermore, particularly in the area of ​​introducing nicotine into the body, it is common to use patches that are applied to the user's skin and deliver the substance to the user's body over a longer period of time.

[0004] For many substances, and especially for nicotine, it is desirable to be able to estimate the amount of the substance already introduced into the human body, for example to reach a predetermined target value of the introduced substance within a defined period or to avoid exceeding a predetermined maximum value.

[0005] In the context of nicotine, in particular, it is desirable for the user to keep track of how much nicotine he or she has already consumed in a defined period, such as on the current day, in order to limit their own consumption or to quit.

[0006] Dispensers are already known from the state of the art, for example liquid dispensers, which use electronic means to record the use of the dispenser, so that the use of the dispenser and the amount of liquid consumed can be read on the dispenser or on a connected smartphone.

[0007] In practice, however, a problem arises, particularly with regard to nicotine, that it is not uncommon for people to ingest this or other substances in different forms. For example, it is not unusual for users to use a patch containing the substance at times, but also, for instance, chewing gum containing it at other times. In such a case, there is a high risk that the person in question will lose track of how much of the substance has already been ingested.

[0008] US 2014 / 346186 A1 discloses a vaporizer system for nicotine cessation that uses sensors to record puffs / doses and connects wirelessly to a smartphone app / server to log and adjust vaping patterns. The system aggregates nicotine intake across multiple sessions and estimates the total amount of nicotine (e.g., mg / day) with limits / warnings.

[0009] US 2015 / 061867 A1 describes a system of different medication dispensers for monitoring medication intake, but does not specifically refer to nicotine. TASK AND SOLUTION

[0010] The invention is defined by the attached claims.

[0011] The object of the invention is to provide a means by which the problem described above can be addressed and people can keep track of the amount of substance ingested.

[0012] According to the invention, a system and a method are proposed for this purpose, which are explained together below.

[0013] The system and method according to the invention can be used to monitor the introduction of the pharmacologically active substance nicotine into the human body. This will be explained below.

[0014] The system comprises at least two dispensers used to deliver the same substance. These two dispensers are designed to deliver the substance in different application forms. The application forms may differ in whether the dispensing by the dispenser is intended for direct introduction into the human body, or whether a further application step follows, such as ingestion or application of chewing gum or a patch dispensed by the dispenser.

[0015] The at least two dispensers are designed to detect any handling associated with the dispensing of a substance. This handling can be the action that not only dispenses the substance from the dispenser but also simultaneously leads to its ingestion by the user. This is the case, for example, with a liquid dispenser that uses a sensor to detect the actuation that applies liquid to the user's mouth or nose. However, the detected handling can also be one that does not directly lead to ingestion but occurs before it. This might be the case, for example, if the dispenser is used to dispense chewing gum or tablets. In this case, the dispenser does not directly detect the ingestion of the gum or tablet, but only the dispensing from the dispenser or the opening of the dispenser's receiving chamber.

[0016] In this case, it is therefore merely assumed that the user actually ingests the chewing gum or tablet as intended after it has been dispensed from the dispenser.

[0017] The at least two donors, who thus monitor the dispensing of the substance, are trained to send the information about the dispensing to a central monitoring device. This central monitoring device is preferably a personal device belonging to the user, such as their computer. In particular, it can be a smartphone whose functionality is extended by a program (app) with regard to the functions described below.

[0018] Via a data connection, in particular a Wi-Fi or Bluetooth connection, at least two dispensers transmit the data for the dispensing of the substance to a smartphone or a central monitoring device of a different type. For this purpose, each dispenser preferably has a radio module. Preferably, the dispensers also have an integrated circuit or processor for evaluating sensor data and controlling the radio module. Furthermore, it is considered advantageous if the dispensers have a storage unit in which they can store data on the recorded handling, so that the data transmission does not have to take place immediately.

[0019] The monitoring device is designed to receive the relevant data for the dispensing of the substance from at least two donors.

[0020] According to the invention, this data is then included in a calculation of the total amount of substance released. This means that the monitoring device uses its processor to calculate the total amount of substance released by the at least two donors, particularly within a limited period, such as the current day.

[0021] The monitoring device can take into account the amount of substance dispensed with each injection. For example, it can consider that a single nicotine patch contains 10 mg of nicotine, while a nicotine spray delivers only 0.5 mg per application. To account for this, the monitoring device could be configured to store the dispensed amount of substance for each donor. However, it is advantageous if the donors themselves transmit not only the number of injections to the central monitoring device, but also the corresponding dispensed amount. In such a case, the monitoring device does not need to be specifically adapted to each individual donor.

[0022] The total quantity of the substance dispensed, calculated by the monitoring device, preferably relates to a defined period, such as a day, a week, or a month. Accordingly, this time-interval-related total quantity is preferably reset to zero at regular intervals, or the dispensing acts to be considered in calculating the total quantity, which are stored in a memory of the monitoring device, are limited in the calculation of the total quantity, in particular to those of the current day, the current week, or the current month.

[0023] The monitoring device, in particular the smartphone, preferably has a display unit, especially in the form of a screen. This display unit primarily shows the calculated total quantity of the substance dispensed by the donors, whereby the absolute quantity itself can be displayed, and alternatively or additionally, a percentage value indicating what proportion of a total or maximum quantity intended for the relevant time interval has already been reached. Preferably, a graphical representation in the form of a progress bar is also provided, allowing the current status to be seen at a glance.

[0024] If a maximum quantity or a target quantity is stored for the corresponding time interval, for example the current day, the remaining quantity of the substance for that time interval can be determined based on the total quantity of the substance already dispensed in that time interval.

[0025] Preferably, the monitoring device is designed to display this remaining amount of substance. To make it particularly easy for the user, the monitoring device can also be designed to convert this remaining amount of substance into a value that displays the number of remaining dispensing sessions specifically for each dispenser in the system. For example, it can display numerical values ​​indicating how many dispensing sessions and uses of patches or sprays would still be available if the entire remaining amount of substance were dispensed using the respective application method.

[0026] The monitoring device is further preferably designed to issue visual or acoustic warnings when the total quantity in the current time interval has already reached a predetermined proportion, for example 50%, of the maximum quantity, or when the total quantity reaches or exceeds the maximum quantity.

[0027] In particular, the following types of dispensers are preferably used in a system according to the invention.

[0028] Preferably, at least one of the dispensers is designed as a liquid dispenser for dispensing the substance in liquid form as an unatomized stream, a spray, or in droplet form. Such a liquid dispenser has a liquid reservoir, the volume of which is preferably 20 ml or less. The liquid containing the active substance is stored here before dispensing. The liquid can be stored in the reservoir under pressure or without pressure. The liquid dispenser also has a dispensing opening through which the liquid is dispensed. An actuating handle, i.e., a force-actuated surface on the dispenser, is provided to effect the dispensing. When this actuating handle is actuated, liquid is pumped from the reservoir to the dispensing opening via a pump or a valve. Preferably, the dispensed quantity is always substantially the same.This can be easily achieved, for example, using a pump and its pump chamber volume.

[0029] The sensors for detecting the dispensing of liquid can be inseparably integrated into the dispenser, for example in the form of a button on the operating handle or a flow meter between the liquid reservoir and the dispensing opening.

[0030] However, a design is particularly preferred in which the liquid dispenser includes an attachment containing the sensors for recording the dispensing process and which is separable from a main assembly of the dispenser, comprising the liquid reservoir, the dispensing channel and the dispensing opening, so that it can be separated from it after the liquid has been consumed and connected to a new dispenser or its main assembly.

[0031] In particular, the attachment may be a device that is mounted on the fluid reservoir or the operating handle and that has a force or pressure sensor which indirectly detects the operating force when the operating handle is actuated.

[0032] A second type of dispenser, which is preferably part of a system according to the invention, is a patch dispenser designed for dispensing patches. This dispenser can hold a plurality of patches, each having a reservoir containing the substance, which rests against the skin when the patch is applied to the user's skin.

[0033] The invention particularly encompasses the following designs. In a first design, the plaster dispenser has a receiving chamber in which the plasters are stored. This receiving chamber is bounded by a movable lid element, which, when open, provides access to the receiving chamber so that the user can remove a plaster after opening it. Although the removal itself can be detected by suitable sensors, it is advantageous if the sensors are preferably designed only to detect the open position. This can be achieved, for example, by a simple force sensor.

[0034] This design assumes that each opening action involves the removal and use of exactly one plaster. If the user removes multiple plasters, this is not readily detectable by the system. However, the monitoring device, particularly the smartphone used for this purpose, can be configured to allow user input, enabling the user to indicate whether they have removed more than one plaster or none at all.

[0035] A more complex alternative design involves a plaster dispenser with an operating handle, allowing the user to remove a single plaster. In this case, the user does not have direct access to the dispenser's storage area but can only remove individual plasters. This means that the operating handle must be activated once for each plaster. The activation of the handle and / or the dispensing of the plaster itself can be detected by suitable sensors and transmitted to the central monitoring device.

[0036] Another type of dispenser, which is preferably part of a system according to the invention, is a chewing gum dispenser or a tablet dispenser.

[0037] Consistent with the descriptions of the plaster dispenser, the two described designs are also possible here: one design in which the dispenser has a storage compartment for the chewing gum or tablets, accessible via a movable lid; and the other design in which a single tablet or piece of chewing gum is dispensed via an operating handle. With the exception of the filling mechanism and, if applicable, the dimensions of the storage compartment, such a dispenser can be structurally identical to the plaster dispenser described.

[0038] However, a different design is considered particularly advantageous for gumball and tablet dispensers. In this design, the gumball or tablet dispenser has a casing into which a package containing individual pieces of gumballs or tablets is inserted. This package can be, in particular, a blister pack with individual compartments for each tablet or piece of gumball. This package is, as intended, at least partially pulled out of the casing to dispense a tablet or piece of gumball.

[0039] Such a gumball and tablet dispenser either has a sensor to detect a dispensing action, allowing the packaging to be pulled out, or it has a sensor that detects when a blockage is released that prevents the packaging from being pulled out. For example, a push button might be provided at an open end of the casing, the two parts of which must be released to remove the packaging. This push button could also function as a sensor that detects when the user has opened it, presumably to remove a tablet or gumball.

[0040] A fourth type of dispenser preferably provided in the system according to the invention is a dispenser for dispensing liquid cartridges. These liquid cartridges themselves serve as liquid reservoirs for a dispensing device, which may in particular be an evaporator designed for use with replaceable liquid cartridges. Such an evaporator is particularly preferably also part of the system according to the invention.

[0041] As already explained for the chewing gum / tablet dispenser and the plaster dispenser, this dispenser for dispensing liquid cartridges is also preferably designed according to one of the construction methods described there. It therefore preferably has either a receiving chamber in which the liquid cartridges are stored and which is accessible by a movable lid element, the opening of which is preferably detected by a sensor, or it has an operating handle that allows for the individual dispensing of a liquid cartridge, the actuation of the operating handle or the dispensing of the liquid cartridge being detected by a sensor.

[0042] The liquid cartridges themselves have a storage container bounded by a wall, which is filled with the substance in liquid form and which has a dispensing port by means of which they are connected to an inlet channel of the said dispensing device, so that the contained liquid can reach a mouthpiece of the dispensing device, where preferably an electrical heating of the liquid takes place for the purpose of evaporation.

[0043] All the aforementioned types of dispensers are characterized by the fact that they incorporate sensors that detect the dispensing of the substance or any handling associated with its dispensing. The sensor used can preferably be very simple, for example, a force or pressure sensor. Furthermore, one of the dispensers in the system has at least one integrated circuit capable of evaluating the sensor data and also configured to communicate with the central monitoring device via a preferably wireless data interface. This data communication is preferably bidirectional and, in particular, preferably follows a WLAN or Bluetooth standard. However, a different radio standard is also conceivable, and optionally even unidirectional communication, in which the dispenser does not receive any data but is solely configured to transmit it.Preferably, the dispensers have a power source in the form of a battery or accumulator. However, dispensers designed for energy harvesting are also possible; that is, they generate electrical energy from the handling required to dispense the substance, which is then used to generate the radio signal. As described above, the dispensers preferably also have a memory to temporarily store recorded dispensing or withdrawal processes, particularly when a radio connection to the central monitoring device cannot be established. BRIEF DESCRIPTION OF THE DRAWINGS

[0044] Further advantages and aspects of the invention will become apparent from the claims and from the following description of preferred embodiments of the invention, which are explained below with reference to the figures. Fig. 1shows an inventive system for the delivery of nicotine and for monitoring this delivery in an overall view. Figs. 2 and 3 show plaster dispensers that are part of the system of Fig. 1 They can be. Fig. 4 shows a liquid dispenser that is part of the system of Fig. 1 may be. Figs. 5 to 7 show tablet or chewing gum dispensers that are part of the system of Fig. 1 They can be. Figs. 8 and 9 show liquid cartridge dispensers that are part of the system of Fig. 1 They can be. DETAILED DESCRIPTION OF THE EXECUTION EXAMPLES

[0045] Fig. 1 Figure 10 shows a system 10 according to the invention for the delivery of nicotine and for monitoring this delivery in an overall view.

[0046] The system comprises a central monitoring device 100, which in this case is a smartphone 100. Many people own such a smartphone 100 nowadays, so this existing device can usually be used advantageously as the central monitoring device. The smartphone 100 has a touchscreen 102 on which information can be displayed and input can be made. A program (app) is installed on the smartphone 100, which provides the monitoring functionality of the system.

[0047] System 10 continues to include a plurality of donors 20, 40, 60, 80, each trained to deliver a drug or nicotine.

[0048] Dispenser 40 is a plaster dispenser 40, which, for example, corresponds to one of the designs of the Figs. 2 and 3It can be designed in various ways. Individual patches can be removed or dispensed from the patch dispenser 40, which are then applied to the user's skin so that they can release the active ingredient, such as nicotine in particular, over a longer period of time.

[0049] When a patch is removed or dispensed, this information is transmitted from the patch dispenser 40 to the smartphone 100 via a wireless interface, such as Bluetooth Low Energy (BLE), and processed by the app on the device. In the simplest case, the transmission can only include information about the removal or dispensing itself. However, additional information, such as the amount of active ingredient or the time of dispensing, can also be transmitted. In a basic configuration, the system 10 can assume that a removed or dispensed patch is applied directly to the user's skin. In a different configuration, however, the app can also prompt the user to confirm that the patch has been applied to the skin.

[0050] Dispenser 20 is designed as a liquid dispenser 20, which dispenses liquid by manual actuation of an operating handle 22. Fig. 4A liquid dispenser 20 suitable for this purpose is shown in more detail. The liquid is preferably introduced directly into the human body during dispensing and, in particular, applied directly to mucous membranes. Specifically, the liquid dispenser can be designed for application of the liquid into the user's eyes, nose, or mouth.

[0051] The liquid dispenser 20 has a liquid reservoir 24, against which the actuating handle 22 can be depressed to dispense liquid. The depressing of the actuating handle 22, and thus indirectly the resulting dispensing through a dispensing opening on the actuating handle 22, can be detected by appropriate sensors. The dispensing information, optionally supplemented by additional data such as the dispensed quantity and / or the time of dispensing, is transmitted to the smartphone 100 and its corresponding app.

[0052] The dispenser 60 is a chewing gum dispenser 60 or tablet dispenser 60, which, for example, corresponds to one of the Figs. 5 to 7 can be trained. Individual pieces of chewing gum 70 or tablets 70 can be taken or dispensed from the dispenser 60, which are then swallowed or chewed by the user so that the active ingredient is absorbed by the body.

[0053] When a piece of chewing gum or a tablet is dispensed, this information is transmitted from the dispenser60 to the smartphone100 via a wireless interface and processed by the app on the device. The app either assumes that the chewing gum or tablet70 has been used immediately, or it displays a dialog on the screen102 to request confirmation from the user regarding the use of the chewing gum or tablet.

[0054] The dispenser 80 is a dispenser for liquid cartridges 90, which, for example, as in Figs. 8 and 9 The liquid cartridges 90 are, after removal from the dispenser 80, applied as intended by means of separate dispensing devices 95, in particular in the form of vaporizers, whereby the user can inhale the contents, in particular the vaporized contents, via such a dispensing device.

[0055] When a liquid cartridge 90 is removed from or dispensed from the dispenser 80, this information is transmitted from the dispenser 80 to the smartphone 100 via a wireless radio interface and processed by the app on the device. The app either assumes that the liquid cartridge 90 is immediately inserted into and used by the dispensing device 95, or it queries the display 102 for the time of use.

[0056] The central monitoring device 100, in this case formed by a smartphone 100, thus receives information from various donors 20, 40, 60, 80 regarding the dispensing of active ingredient, possibly supplemented by the specific amount of active ingredient dispensed.

[0057] The central monitoring device 100 can store this information separately for dispensers 20, 40, 60, and 80 and then add up the respective amounts of active ingredient to calculate the total consumption of the medication or nicotine. The corresponding value, currently 32 milligrams in this example, is displayed on the screen 102 so that the user is informed. The screen also indicates that the specified maximum daily amount is 45 milligrams and how many patches (50), chewing gum (70), liquid cartridges (90), or sprays from the liquid dispenser are permitted for the remaining 13 milligrams.

[0058] In the case of use for nicotine, the user can thus easily maintain an overview and divide the remaining amount up to the maximum amount in an individually desired manner.

[0059] The other figures serve as examples of possible donors, illustrating them in more detail.

[0060] Fig. 2 Figure 40 shows a first variant of a plaster dispenser 40 in its closed and open states. The plaster dispenser 40 has a storage compartment 42 in which several plasters 50 are stored. The storage compartment can be accessed from the outside by swinging open a cover element 44, allowing a plaster 50 to be removed. The opening of the dispenser 40 is detected by a sensor 46, for example a push button, and transmitted to the monitoring device 100 via a processor 57 and a radio module 58, which are powered by a battery 59.

[0061] Fig. 3Figure 1 shows a second variant of a plaster dispenser 40. This dispenser also has a receiving chamber for plasters 50. However, this chamber is not directly accessible. Instead, the dispenser 40 has a dispensing slot 55 through which individual plasters 50 can be dispensed by means of an operating handle 52. This dispensing can be detected by means of a sensor 54, for example, in the form of a potentiometer. The dispensing information is then transmitted via a processor 57 and a radio module 58 to the monitoring device 100.

[0062] Fig. 4Figure 1 shows a variant of a liquid dispenser 20. As already described, this dispenser has a liquid reservoir 24, against which an actuating handle 22 can be pressed to actuate an internal pump or open a dispensing valve. The liquid can be dispensed as an unatomized jet or a spray, or as individual droplets through a dispensing opening 23. Designs in which a predetermined quantity of liquid is dispensed are particularly preferred.

[0063] Although one possible technical design involves an integrated sensor detecting this actuation, it is preferred that the liquid dispenser 20 has an attachment 30, which is not essential for the functionality of the dispensing mechanism itself and which is additionally attached to detect the actuation. In this case, the attachment 30 has a tubular section into which a housing part 26 of the liquid dispenser 20 is inserted. A force sensor 32 is provided at the bottom of this tubular section, which detects the corresponding force when force is applied to the handle 22 and can thereby recognize whether actuation and, presumably, dispensing have occurred. If actuation and dispensing have taken place, this is transmitted to the monitoring device 100 by the processor 37 and the radio module 38.

[0064] Figs. 5 to 7Show different variations of a gumball dispenser 60. In the design of the Fig. 5 This includes a cover 61, for example made of imitation leather, into which a blister pack 71 containing a number of chewing gums 70 is inserted. The blister pack 71 can be pulled out of the cover 61 using a pull tab 73, but only after a snap fastener 66 has been released. This snap fastener 66 also acts as a sensor, allowing the processor 77 to detect that the snap fastener has been released. This is interpreted as a signal that the user is pulling out the blister pack 71 and removing and using a piece of chewing gum 70. This information is transmitted to the monitoring device via the radio module 78.

[0065] The variations of the chewing gum dispenser Figs. 6 and 7 They essentially correspond to the plaster dispensers of the Figs. 2 and 3 How to Fig. 2 described, the design of Fig. 6a dispenser with a receiving chamber 62, in which, in this case, individual pieces of chewing gum are stored, possibly in a blister pack 71. The opening of the lid element 64 is detected by a sensor 66 and reported to the monitoring device 100 via the radio module 78. In the design of the Fig. 7 accordingly Fig. 3 to provide a dispenser for individual dispensing, in this case of chewing gum 70, which can be dispensed individually by means of an operating handle 72 for consumption by the user. The actuation of the operating handle 72 is detected by a suitable sensor 74 and the resulting dispensing is transmitted to the monitoring device 100.

[0066] The Figs. 8 and 9 The dispensers shown are for liquid cartridges 90. As described above, these are cartridges that are used in dispensing devices, such as evaporators, to dispense the liquid they contain.

[0067] The donors of Figs. 8 and 9 They essentially correspond to the plaster dispensers of the Figs. 2 and 3 The donor of Fig. 8 This allows access to a receiving chamber 82, in which the cartridges are stored and from which they can be removed, with the sensor 86 detecting the opening of the cover element 84, so that this can be sent via the processor 97 and the radio module 98 to the monitoring device 100. The dispenser of the Fig. 9 This in turn allows the individual discharge of the cartridges 90, whereby the discharge is detected by a sensor 94 on the operating handle 92 and reported to the monitoring device 100.

Claims

1. System (10) for monitoring the intake of nicotine, having the following features: a. the system (10) has at least two dispensers (20, 40, 60, 80) for delivering nicotine, wherein the two dispensers (20, 40, 60, 80) are designed to deliver nicotine in a different application form, and b. the system (10) has a monitoring device (100) connected to the at least two dispensers (20, 40, 60, 80) by a data link, and c. the two dispensers (20, 40, 60, 80) are designed to detect a handling associated with the delivery of nicotine and, in reaction hereto, to transmit data relating to the delivery of the nicotine to the monitoring device (100), and d. the monitoring device (100) is designed to receive the data relating to the delivery of the nicotine from the at least two dispensers (20, 40, 60, 80) and to calculate a total quantity of the delivered nicotine, and e. at least one of the dispensers (40) is provided as a patch dispenser (40) for delivering patches (50), wherein the patch dispenser (40) is filled with a plurality of patches (50), which each have a store provided with nicotine which, when the patch is applied to the skin of a user, rests on the skin, and / or at least one of the dispensers (60) is designed as a chewing gum dispenser (60), wherein the chewing gum dispenser (60) is filled with a plurality of pieces of chewing gum (70), which each contain nicotine.

2. System (10) according to Claim 1, having the following further feature: a. the monitoring device (100) has an indicating device (102) and is designed to display the total quantity of the delivered nicotine on the indicating device (102).

3. System (10) according to either of the preceding claims, having the following further feature: a. the monitoring device (100) is designed to calculate the total quantity over a limited time period, in particular over one day.

4. System (10) according to one of the preceding claims, having at least one of the following further features: a. the monitoring device (100) is designed to compare the total quantity with a predefined maximum quantity and to output a warning message if the total quantity is reached and / or exceeded, and / or b. the monitoring device (100) is designed to compare the total quantity with an envisaged maximum quantity and to calculate what delivery quantity is still available on the current day, in the current week or in the current month.

5. System (10) according to one of the preceding claims, having the following further feature: a. at least one of the dispensers (20) is designed as a liquid dispenser (20) for delivering nicotine in liquid form as a non-atomized jet, as a spray jet or in droplet form, in particular having at least one of the following additional features: b. the at least one liquid dispenser (20) has an actuating handle (22) and is designed to detect an actuation of the actuating handle (22), and / or c. the at least one liquid dispenser (20) has an attachment (30), which is detachably coupled to a housing part (26) of the liquid dispenser (20) and is designed to detect the handling of the liquid dispenser (20), and / or d. the at least one liquid dispenser (20) has a liquid store (24), the content of which comprises nicotine, and / or e. the at least one liquid dispenser (20) is designed as a pump dispenser.

6. System (10) according to one of the preceding claims, having at least one of the following additional features: a. the patch dispenser (40) has a receiving chamber (42) for receiving the patches (50), wherein a movable cover element (44) is provided which, in an opened position, permits access to the receiving chamber (42) and the removal of a patch (50), wherein the patch dispenser (40) preferably has a sensor (46) for detecting the opened position, and / or b. the patch dispenser (40) has an actuating handle (52), by means of which an individual patch (50) can be removed from the patch dispenser (40), wherein the patch dispenser (40) preferably has a sensor (54) for detecting the actuation of the actuating handle (52).

7. System (10) according to one of the preceding claims, having at least one of the following additional features: a. at least one of the dispensers (60) is designed as a tablet dispenser (60), and / or b. the chewing gum dispenser (60) or tablet dispenser (60) has a sleeve (61), into which a packaging means (71) with individual pieces of chewing gum (70) or tablets (70) is contained, wherein the packaging means (71) can be drawn out of the sleeve (61) to remove a piece of chewing gum (70) or a tablet (70), and wherein the pulling out of the packaging means (71) or the release of a blockage in order to be able to pull out the packaging means (71) can preferably be detected by means of a sensor (66), and / or c. the chewing gum dispenser (60) or tablet dispenser (60) has a receiving chamber (62) for receiving the chewing gum (70) or tablets (70), wherein a movable cover element (64) is provided which, in an opened position, permits access to the receiving chamber (62) and the removal of a piece of chewing gum (70) or a tablet (70), wherein the chewing gum dispenser (60) or tablet dispenser (60) preferably has a sensor (66) for detecting the opened position, and / or d. the chewing gum dispenser (60) or tablet dispenser (60) has an actuating handle (72), by means of which an individual piece of chewing gum (70) or an individual tablet (70) can be removed from the chewing gum dispenser (60) or tablet dispenser (60), wherein the chewing gum dispenser (60) or tablet dispenser (60) preferably has a sensor (74) for detecting the actuation of the actuating handle (72).

8. System (10) according to one of the preceding claims, having the following further feature: a. at least one of the dispensers (80) is designed to deliver liquid cartridges (90), wherein these liquid cartridges (90) are provided to be coupled to a delivery device (95), preferably having at least one of the following additional features: b. the dispenser (80) has a receiving chamber (82) for receiving the liquid cartridges (90), wherein a movable cover element (84) is provided which, in an opened position, permits access to the receiving chamber (82) and the removal of a liquid cartridge (90), wherein the dispenser (80) preferably has a sensor (86) for detecting the opened position, and / or c. the dispenser (80) has an actuating handle (92), by means of which an individual liquid cartridge (90) can be removed from the dispenser (80), wherein the dispenser (80) preferably has a sensor (94) for detecting the actuation of the actuating handle (92).

9. System (10) according to one of the preceding claims, having the following further features: a. at least one of the at least two dispensers (20, 40, 60, 80) is provided as a patch dispenser (40) and at least one of the at least two dispensers is designed as a liquid dispenser (20), and / or b. at least one of the at least two dispensers (20, 40, 60, 80) is provided as a patch dispenser (40) and at least one of the at least two dispensers is designed as a chewing gum dispenser (60) or tablet dispenser (60), and / or c. at least one of the at least two dispensers (20, 40, 60, 80) is provided as a patch dispenser (40) and at least one of the at least two dispensers is designed as a dispenser (80) for delivering liquid cartridges (90), and / or d. at least one of the at least two dispensers (20, 40, 60, 80) is provided as a liquid dispenser (20) and at least one of the at least two dispensers is designed as a chewing gum dispenser (60) or tablet dispenser (60), and / or e. at least one of the at least two dispensers (20, 40, 60, 80) is provided as a liquid dispenser (20) and at least one of the at least two dispensers is designed as a dispenser (80) for delivering liquid cartridges (90), and / or f. at least one of the at least two dispensers (20, 40, 60, 80) is provided as a chewing gum dispenser (60) or tablet dispenser (60) and at least one of the at least two dispensers is designed as a dispenser (80) for delivering liquid cartridges (90).

10. System (10) according to one of the preceding claims, having at least one of the following further features: a. the data link is a WLAN or Bluetooth data link or a GSM, 3G, 4G or 5G mobile radio link, and / or b. the monitoring device (100) and at least one of the dispensers (20, 40, 60, 80) are designed for a coupling operation, in the course of which an unambiguous identifier on the dispenser is read by the smartphone, and / or c. the monitoring device (100) is formed by a computer, in particular a smartphone (100) or a tablet computer.

11. Method for monitoring the intake of nicotine from a plurality of dispensers (20, 40, 60, 80) in a different application forms, having the following features: a. on at least two dispensers (20, 40, 60, 80) which are designed to deliver the nicotine in different application forms, the respective handling of the dispenser (20, 40, 60, 80) is detected via sensors, and b. the at least two dispensers (20, 40, 60, 80) send data relating to the delivery of the nicotine to a monitoring device (100) in reaction thereto, and c. the monitoring device (100) receives the data and, on the basis of the same, calculates a total quantity of the nicotine delivered by the at least two dispensers (20, 40, 60, 80), and d. at least one of the dispensers (40) is provided as a patch dispenser (40) for delivering patches (50), wherein the patch dispenser (40) is filled with a plurality of patches (50), which each have a store provided with nicotine which, when the patch is applied to the skin of a user, rests on the skin, and / or at least one of the dispensers (60) is designed as a chewing gum dispenser (60), wherein the chewing gum dispenser (60) is filled with a plurality of pieces of chewing gum (70), which each contain nicotine.

12. Method according to Claim 11, having the following further feature: a. at least one of the dispensers (20, 40, 60, 80) detects a handling of the dispenser which is used to open a receiving chamber (42, 62, 62, 82) and sends data to the monitoring device as a reaction thereto.

13. Method according to Claim 11 or 12, having the following further feature: a. at least one of the dispensers (20, 40, 60, 80) detects a handling of the dispenser which causes the delivery of the nicotine, and sends data to the monitoring device as a reaction thereto, in particular having at least one of the following additional features: b. by means of a sensor, the dispenser detects the application of force and / or displacement of an actuating handle, and / or c. the delivery is carried out in liquid form, in particular as a non-atomized jet, as a spray jet or as droplets, or d. the delivery is carried out in the form of a patch (50), a piece of chewing gum (70) or a tablet, which are ingested or applied by a user following the delivery, or e. the delivery is carried out in the form of a liquid cartridge (90), which is inserted into an applicator following the delivery.