PROCESSING ORDER

Description

[0001] The invention relates to a processing arrangement for tissue material harvested from a patient and to be reapplied after processing, such as, in particular, autologous cartilage tissue from a joint or bone material, according to the preamble of claim 1, and to a collection processing system with such a processing arrangement. The processing arrangement comprises a collection container with a collection receptacle for receiving tissue material that has been harvested by means of a tissue harvesting device or a shaver. Furthermore, the processing arrangement comprises a processing container that forms a mixing receptacle, which serves for the combined receiving of the tissue material with a liquid to pasty medium, which is, for example, formed by a hydrogel or contains autologous conditioned plasma or blood serum.Furthermore, the preparation arrangement includes a preparation device that serves to mix or suspend the tissue material in the medium in order to produce a pasty application mass.

[0002] The AutoCart™ system is known for obtaining autologous tissue material, producing blood serum, creating a paste from the tissue material and blood serum, and applying the paste. In this system, the tissue material, harvested and pulverized by a tissue collection device, is separated from a fluid stream into a collection container. From there, it is drawn into a syringe. This syringe is connected via an adapter to a second syringe containing the blood serum. By repeatedly pushing the plungers of both syringes back and forth, the contents are mixed to form the paste-like application mixture.

[0003] A disadvantage of the known system is that contamination or bacterial growth can occur when transferring the tissue material from the collection container to the syringe. This risk of contamination is even greater if, depending on the application, additional particle size reduction of the tissue material is required. Furthermore, the known procedure for mixing the tissue material with the blood serum is relatively time-consuming and often results in insufficient homogeneity of the application mixture.

[0004] US 2020 / 0061258 A1 discloses an arrangement for deagglomerating extracted grease so that, after processing it into a lump-free medium, it can be reinjected using minimally invasive techniques. The arrangement comprises two syringes connected by a sieve-like connecting element such that extracted grease can be transferred back and forth between the two syringes by passing through the connecting element. Cutting edges are provided at the openings of the connecting element, which can be used to break up any lumps contained in the grease.

[0005] JP 2006 230686 A describes a device for the production of bone grafts comprising a syringe-shaped liquid container for receiving and dispensing a liquid component, a solid container for receiving and dispensing a solid, and a mixing container into which the liquid component and the solid can be injected. The mixing container can be subjected to a vibrator to mix the liquid component and the solid.

[0006] US 6 071 284 A discloses a preparation arrangement for tissue material taken from a patient and to be applied after preparation, such as in particular autologous cartilage or bone tissue, comprising a collection container, a preparation container and a preparation device.

[0007] The object of the invention is to avoid the aforementioned disadvantages in a generic preparation arrangement and to enable sterile preparation of the tissue material as well as high homogeneity of the produced application mass.

[0008] This problem is solved by a processing arrangement with the features of claim 1. A connecting device is provided, in which, for the formation of a cassette-like insertion unit by jointly receiving the collection container and the processing container, first fastening means for attaching the collection container and second fastening means for attaching the processing container, as well as a through-opening positioned in a fastening position between the collection container and the mixing container, are provided, wherein the cassette-like insertion unit can be inserted into a processing receptacle of the processing device to carry out a processing operation. This allows the collection container to be connected to the processing container via the connecting device in order to enable direct discharge of the tissue material from the collection container into the processing container.This prevents the tissue material from being freely removed from the collection container, which could lead to contamination. Instead, the collection container and the processing container can be sealed to the outside and attached to the connecting device using the fastening devices, thus ensuring a sterile transfer of the tissue material.

[0009] In a particularly advantageous embodiment, a shredding tool is provided at the through-opening. This allows the fabric material to be shredded to a desired particle size during the externally shielded transfer from the collection container to the receiving container. Therefore, the fabric material does not need to be removed from the collection container for further shredding.

[0010] Preferably, the shredding tool is formed by a disc rotatably mounted on the connecting device, with at least one cutting element. The disc-shaped shredding tool allows a maximum particle size to be set for all the tissue material being transferred. Furthermore, the disc-shaped shredding tool can be integrated into the connecting device particularly easily. In the unpowered state, it closes the through-opening, and when activated, it transfers the tissue material to the processing container in conjunction with the shredding process. Advantageously, the disc-shaped shredding tool can be positioned in a specific rotational position in which the through-opening is essentially completely sealed.In this way, it can be avoided that the tissue material prematurely and unshredded escapes from the collection container into the processing container and / or that the tissue material, the medium or the mixture produced therefrom passes from the processing container into the collection container during the mixing process.

[0011] Furthermore, it is advantageous if an externally driven mixing tool protrudes into the mixing chamber of the processing container. This allows for the integration of a mixing tool that is adapted to the shape and size of the processing container, as well as to the quantity of tissue material to be processed and the medium to be mixed with it. This ensures optimized application and mixing of the contents held in the processing container.

[0012] Advantageously, the mixing tool is formed by a whisk that is rotatably mounted on the processing container and driven by the processing device, thereby ensuring a particularly homogeneous mixing of the tissue material with the respective medium.

[0013] Furthermore, the collection container preferably has a closing element that is adjustable between a closed position, in which it closes the collection receptacle, and an open position, in which the collection receptacle is at least partially open. This allows the collection container to be securely closed when separated from both the collection arrangement and the processing arrangement, thus preventing contamination of the collected tissue material, for example, during transfer from the collection arrangement to the processing arrangement.

[0014] It is advantageous if the locking element can be automatically moved into a second open position when the first fastening elements of the connecting device are connected to the first counter-fastening elements of the collection container, in which a container opening of the collection container 8 is released. In this way, it is ensured that the collection receptacle is ready for the discharge of the tissue material to the processing container when the collection container is connected to the connecting device.

[0015] Advantageously, the first fastening elements and the first counter-fastening elements form a first insertion connection, wherein the closing element is formed by a sliding element that can be moved from the closed position to the second open position by an insertion movement of the first fastening elements relative to the first counter-fastening elements. In this way, the collection container can be permanently shielded from the outside even during the formation of the first insertion connection between the collection container and the connecting device, in order to prevent contamination.

[0016] The processing container preferably has a closure element that is adjustable between a closed position, in which it closes the mixing receptacle, and a receiving position, in which the mixing receptacle is open. This allows the processing container to be securely closed even when separated from the connecting device or the collection container, thus preventing contamination of the medium before processing and / or contamination of the application compound received after processing. Furthermore, the closing element of the collection container, which can be moved to the second open position, and the closure element of the processing container, which can be adjusted to the receiving position, allow the collected tissue or the application compound produced from it to be removed as needed at any process step.In this way, the collected tissue material, whether unprocessed, shredded, or already mixed with the medium, is available in whole or in part at any time for further processing or use.

[0017] It is advantageous if the locking element can be automatically moved into the receiving position when the second fastening elements of the connecting device are connected to the second counter-fastening elements of the processing container. This ensures that the mixing chamber is ready to receive the tissue material from the collection container when the processing container is connected to the connecting device.

[0018] Advantageously, the second fastening elements and the second counter-fastening elements form a second insertion connection, wherein the locking element is formed by a locking slide which, through an insertion movement of the second fastening elements relative to the second counter-fastening elements, can be moved from the closed position to the receiving position by contact with the connecting device. In this way, the mixing chamber can be permanently sealed off from the outside even during the formation of the second insertion connection of the processing container with the connecting device, in order to prevent contamination.

[0019] In a particularly preferred embodiment, the processing device comprises, in addition to the processing receptacle for the connecting device with the attached collection container and processing container, at least one drive, wherein the drive forms a first drive connection with the mixing tool in a receptacle position. The common receptacle of the collection container and the processing container in the connected state within the processing device ensures permanent containment of the container contents and the resulting application compound, even during processing. The drive of the processing device enables a mechanized mixing process.

[0020] Advantageously, at least one drive in the receiving position also has a second drive connection to the shredding tool. In this way, the shredding of the tissue material can also be carried out mechanically by the processing device as it is discharged from the collection container.

[0021] Furthermore, it is advantageous if the collection container has a piston for emptying the collection chamber towards the through-opening to allow for complete ejection of the collected tissue material.

[0022] Preferably, the preparation container has at least one closable inlet / dispensing port. The application material can be drawn into a syringe-like applicator via this inlet / dispensing port and subsequently applied to the lesion to be treated. Furthermore, additional medium can be added to the mixing container via this inlet / dispensing port during the preparation process, if required. For example, a first inlet / dispensing port, whose shape, size, and position are adapted to a specific applicator, and a second inlet / dispensing port, whose shape, size, and position are designed for convenient introduction of the medium, are provided.

[0023] Advantageously, the preparation container is equipped with a slide gate for emptying the mixing chamber, to which at least one inlet / outlet port is attached, allowing the mixing chamber to be emptied. This slide gate enables essentially complete removal of the prepared pasty application compound and easier and more uniform filling of the applicator.

[0024] Advantageously, the processing device additionally includes at least one actuator for actuating the piston and / or the slide valve to enable automatic or automated dispensing of the tissue material from the collection container and / or dispensing of the processed application compound from the processing container. This allows for a largely automated execution of the entire processing process after the interconnected collection and processing containers have been attached to the processing device. The individual processing steps, consisting of dispensing the tissue material, shredding the tissue material, mixing the tissue material with the medium, and dispensing the prepared application compound, can be performed at least partially automatically by the processing device.Additionally or alternatively, the slide can also be operated manually, for example by means of an applicator being filled. In this way, the mixing container can be completely emptied independently of the preparation device, particularly to ensure that the prepared application mixture is dispensed as evenly and completely as possible from the preparation container to the applicator.

[0025] The processing device preferably includes an electronic device for at least partially automated activation of the at least one drive and / or the at least one actuator. This allows all or individual processing steps to be carried out semi- or fully automatically and coordinated in time.

[0026] In a particularly preferred embodiment, a camera is also provided on the processing device for capturing images of the mixture. This enables continuous optical monitoring of the processing operation and the resulting application compound, for example, on a screen connected to the camera. The screen can be, for instance, a touchscreen on the processing device, which also serves to input control commands. Alternatively or additionally, automated evaluation of the captured image information can also be provided, for example, to control or regulate the processing device during a processing operation.

[0027] Furthermore, the aforementioned problem is solved by a collection / processing system with a processing arrangement in one of the aforementioned embodiments, wherein the collection container can additionally be detachably fixed to a connection housing of a collection device, which is arranged for separating and collecting tissue from a fluid flow between a tissue sampling device and a vacuum device. In this way, the tissue material in question can be collected in the collection container after removal via the tissue sampling device, dispensed into the processing container after the collection container has been removed from the rest of the collection device and connected to it, processed in the processing device, and then dispensed to the applicator without having to remove it freely from either container.Rather, the tissue material, or the application compound produced from it, is continuously shielded from the outside and protected against contamination from collection to absorption in the applicator. In this way, the application compound can be kept as sterile as possible.

[0028] Advantageously, the collection container forms a flow section of a connecting path that can be established in a collection position between a flow port on the shaver side, which is flow-connected to the tissue sampling device, and a flow port on the vacuum side, which is flow-connected to the vacuum device. This allows the tissue material separated by the collection device from a fluid flow between the tissue sampling device and the vacuum device to be collected directly in the removable collection container during separation. In this way, the tissue material is immediately available for further processing after the collection container is removed.

[0029] Preferably, when the collection container is removed from the connection housing, the closing element of the collection container can automatically move from an initial open position, in which the access opening is released, to the closed position to ensure continuous, protected containment of the collected tissue material. For this purpose, the closing element can, for example, be pre-tensioned into the closed position by a spring mechanism.

[0030] It should be noted that all the features of the object according to the invention described above are interchangeable or combinable with each other, provided that such an exchange or combination is not excluded for technical reasons.

[0031] The figures illustrate an exemplary embodiment of the invention. They show: Figure 1 shows a perspective view of a collection / processing system with a processing arrangement according to the invention, Figure 2 shows a longitudinal section through a collection device of the collection arrangement according to Figure 1 Figure 3 shows the collection / processing system according to Figure 1 with a feed unit prepared for a processing operation, Figure 4 a view of the feed unit after Figure 3 In a separated state, Figure 5 shows a section through the insertion unit. Figure 3 in the ready-to-use state, Figure 6 shows a perspective view of a processing device of the processing arrangement with the insertion unit installed, and Figure 7 shows a section through the processing device. Figure 6 .

[0032] Fig. 1Figure 1 shows a collection / processing system 2 for tissue material G, such as autologous cartilage tissue from a joint or bone material, which is to be taken from a patient P and applied after processing. The collection / processing system comprises a collection arrangement 4 for collecting the tissue material G and a separate processing arrangement 6 for processing the collected tissue material G. The collection arrangement 4 and the processing arrangement 6 are used in conjunction with a common collection container 8.

[0033] The collection arrangement 4 includes a collection device 10 for a tissue extraction device 12 formed by a shaver, by means of which tissue material G, such as cartilage or bone tissue in particular, can be extracted from patient P. The tissue material G is extracted, for example, from a knee or shoulder joint or from a bone. The tissue material G obtained in this way is used later for the reconstruction of tissue or bone at a defect of patient P.

[0034] To collect the tissue material G in the collection container 8, the collection device 10 has a shaver-side flow port 14, which is fluidly connected via a connecting line 16 to a discharge port 18 of a tissue discharge 20 of the tissue removal device 12. In addition, the collection device 10 has a vacuum-side flow port 24, which can be connected to the shaver-side flow port 14 via a connecting path 22 and is fluidly connected via a connecting line 26 to a vacuum device 28.

[0035] As soon as a vacuum is applied to the connecting line 26 by means of the vacuum device 28, a fluid flow F is generated from the tissue sampling device 12 via the collecting device 10 to the vacuum device 28. The tissue material G removed by a tool 30 can then be transported to the discharge port 18 by means of the tissue discharge port 20 in order to feed it into the collection container 8 of the collecting device 10.

[0036] As especially from Figure 2As can be seen, the collection container 8 is fixed to a connection housing 32 such that it forms a flow section 36 between an inlet opening 38 and an outlet opening 40 with a collecting receptacle 34. The inlet opening 38 is integrated into a closing element 42, which, in a first open position shown, only opens the inlet opening 38 and otherwise closes a container opening 44 of the collection container 8. The collecting receptacle 34 is partially limited by a sieve device 46, which has at least one flat sieve surface 48 in front of the outlet opening 40 in the direction of flow of the fluid flow F.

[0037] As from Figure 2As can also be seen, the connection path 18 runs from the shaver-side flow connection 14 via the flow section 36 to the negative pressure-side flow connection 24. In this way, the tissue material G carried along in the fluid flow F can be separated by means of the sieve device 46 and collected in the collection receptacle 34.

[0038] Once a sufficient quantity of the tissue material G has been collected, the collection container 8 can be separated from the connection housing 32 of the collection device 10 in order to Figure 3 to be attached to a connecting device 50 of the separate processing arrangement 6. The connecting device 50 serves to jointly accommodate the collection container 8 and a processing container 52 in order to form a cassette-like insertion unit 54. This can be inserted into a processing receptacle 56 of a processing device 58 to carry out a processing operation.

[0039] To ensure protected and externally shielded storage of the collected tissue material G when transferring the collection container 8 from the collection arrangement 4 to the processing arrangement 6, the closing element 42 is moved from the first open position when the collection container 8 is removed from the connection housing 32 according to Figure 2 automatically moved into a closed position in which both the container opening 44 and the access opening 38 are closed, as in Figure 4As shown, the closing element 42 can, for example, be pre-tensioned in the direction of the closed position, or driving means can be provided that move the closing element 42 into the closed position by means of relative movement with respect to the connection housing 32 (not shown). In any case, the fabric material G received in the collecting receptacle 34 can no longer escape through the container opening 44 or the access opening 38 and is protected against external contamination as soon as the closing element 42 is in the closed position.

[0040] To attach the collection container 8 to the connecting device 50, the latter has first fastening means 60 which interact with first counter-fastening means 62 of the collection container 8. The first fastening means 60 and counter-fastening means 62 have, for example, interlocking rail elements that enable a first insertion connection 64, during the formation of which the slide-shaped closing element 42 of the collection container 8 automatically moves into a second open position according to Figure 5 is movable. In this second open position, the closing element 42 at least largely releases the container opening 44.

[0041] As in Figure 4 As further shown, the processing container 52 can also be attached to the side of the connecting device 50 facing away from the collection container 8 to form the insertion unit 54.

[0042] For fastening the processing container 52, the connecting device 50 has second fastening means 66 which interact with second counter-fastening means 68 of the processing container 52. The second fastening means 66 and counter-fastening means 68 also have, for example, interlocking rail elements that enable a second insertion connection 70, during the formation of which a closing element 72 of the processing container 52 is moved from a closed position according to Figure 4 , in which a mixed intake 74 is closed, automatically into an intake position according to Figure 5 The locking element 72 is displaceable, in which a receiving opening 76 of the mixing receptacle 74 is released. For this purpose, the locking element 72 is designed, for example, as a slide and can be displaced via a contact on the connecting device 50 as a result of the insertion movement.

[0043] The mixing inlet 74 of the processing container 52 serves for the joint intake and processing of the tissue material G with a liquid to pasty medium M, which is formed, for example, by a hydrogel or blood serum. The medium M can be, as in Figure 5 The mixture is shown to be pre-portioned and already included in the mixing intake 74, and / or is fed into the mixing intake 74 during a processing process via at least one lockable input / output port 78 or 78A of the processing container 52. For example, a first input / output port 78 is defined by its shape, size, and position on a specific applicator 112 (see Figure 1). Figure 7 ) is coordinated, and a second input / output port 78A is provided, which is designed in its shape, size and position for the purpose of convenient input of the medium M.

[0044] As from Figure 5As can be further seen, the connecting device 50 has a through-opening 80 which, in the illustrated mounting position of the insert unit 54 with attached collection container 8 and processing container 52, is arranged between the container opening 44 and the receiving opening 76. The connecting device 50 also has a shredding tool 82 that extends over the through-opening 80. The shredding tool 82 is, for example, disc-shaped and rotatably held in the connecting device 50. The shredding tool 82 has at least one cutting element, preferably a plurality of cutting elements. The disc-shaped shredding tool 82 can advantageously be moved into a specific rotational position in which the through-opening 80 is substantially completely sealed.In this way, it can be avoided that the tissue material G prematurely and unshredded escapes from the collection container 8 into the processing container 52 and / or that the tissue material G, the medium M or the mixture produced therefrom enters the collection container 8 from the processing container 52 during the mixing process.

[0045] In addition, a mixing tool 84 is provided on the processing container 52, which is formed, for example, by a rotatably mounted whisk that projects into the mixing receptacle 74.

[0046] As from Figure 6As can be seen, the insertion unit 54 can be inserted into the processing receptacle 56 of the processing device 58 in the manner of a cassette. In this receptacle position, the tissue material G collected in the collection container 8 and the medium M collected in the processing container 52 can be processed into the desired application mass by applying the processing device 58.

[0047] As from Figure 7As can be seen, the processing device 58 has a first drive 86 which, in the receiving position, establishes a first drive connection 88 with coupling means 90 of the mixing tool 84. The processing device 58 also has a second drive 92 which, in the receiving position, establishes a second drive connection 94 with the comminution tool 82. The first drive 86 and the second drive 92 can, as shown, be formed by parts of a common gearbox, which in turn can be driven by a common motor 96. Alternatively, both drives 86, 92 can also be designed and activated separately (not shown).

[0048] Furthermore, the processing device 58 has a first actuator 98 by means of which a piston 100 of the collection container 8 can be moved towards the container opening 44 in order to empty the collection receptacle 34. The processing device 58 also has a second actuator 102 by means of which a slide 104 of the processing container 52 can be moved, to which the inlet / outlet port 78 is attached, in order to empty the mixing receptacle 74 via this port. Additionally or alternatively, the slide 104 can also be operated manually, for example by means of the applicator 112 connected to the inlet / outlet port 78. In this way, the mixing receptacle 74 can also be completely emptied independently of the processing device 58, for example to dispense a prepared application mixture from the processing container 52 to the applicator 112.

[0049] Furthermore, the processing device 58 includes electronics 106 by means of which the drives 86, 92 or their motor 96, as well as the actuators 98, 102, can be activated. It can be provided that the electronics 106 allows a processing process to run at least semi-automatically, and advantageously fully automatically. Operation or programming of the electronics 106 is possible, for example, via a touchscreen 108. Image information generated by a camera 110, which is directed at the mixing camera 74, as shown in [reference missing], can also be displayed on this touchscreen. Figure 6 depicted.

[0050] During a processing operation, the receiving position is adjusted according to Figure 7By activating the motor 96 via the first drive 86, the whisk-shaped mixing tool 84 is set in motion, and simultaneously, via the second drive 92, the disc-shaped shredding tool 82 is set in rotation. This shreds the tissue material G held in the collection holder 34, and it passes through the opening 80 into the processing container 52, where it can be mixed with the medium M.

[0051] By activating the first actuator 98, the piston 100 can be moved to ensure complete comminution and complete delivery of the tissue material G to the mixing intake 74.

[0052] After the shredded tissue material G is delivered to the mixing chamber 74, it is mixed with the medium M until a suitable application mass is produced. If necessary, additional medium M can be added to the mixing chamber 74, particularly via the input / output port 78A.

[0053] Once the application compound is ready, the inlet / dispensing port 78 can be connected to the applicator 112, which is in the form of a syringe and filled with the application compound. To assist in drawing up the applicator 112 and to ensure that the mixing chamber 74 is emptied as completely as possible, the second actuator 102 can be activated to move the slide 104 with the inlet / dispensing port 78.

[0054] It should be noted that all the elements and features described above of the various embodiments of the object according to the invention are interchangeable or combinable with each other, provided that such an exchange or combination is not excluded for technical reasons.

Claims

1. A processing arrangement (6) for tissue material (G) removed from a patient (P) and to be applied after processing, such as in particular autologous cartilage or bone tissue, comprising: a collection container (8) which has a collection receptacle (34) for receiving the tissue material (G) removed by a tissue removal device (12), a processing container (52) which has a mixing receptacle (74) for jointly receiving the tissue material (G) and a liquid to pasty medium (M), and a processing device (58) for mixing the tissue material (G) and the medium (M), characterized in that a connection device (50) is provided on which, for forming a cassette-like slide-in unit (54) by jointly receiving the collection container (8) and the processing container (52), first fasteners (60) for attaching the collection container (8) and second fasteners (66) for attaching the processing container (52) as well as a passage opening (80) which can be positioned between the collection receptacle (34) and the mixing receptacle (74) are provided, wherein the cassette-like slide-in unit (54) can be slid into a processing receptacle (56) of the processing device (58) for carrying out a processing operation.

2. Processing arrangement according to claim 1, characterized in that a comminuting tool (82) is provided at the passage opening (80), wherein the comminuting tool (82) is formed in particular by a disc rotatably mounted on the connection device (50) and has at least one cutting element.

3. Processing arrangement according to claim 1 or 2, characterized in that a mixing tool (84) projects into the mixing receptacle (74) on the processing container (52), wherein the mixing tool (84) is formed in particular by an agitator rotatably mounted on the processing container (52) and drivable by the processing device (58).

4. Processing arrangement according to any one of claims 1 to 3, characterized in that the collection container (8) has a closing element (42) which can be adjusted between a closed position in which it closes the collection receptacle (34) and an open position in which the collection receptacle (34) is at least partially open.

5. Processing arrangement according to claim 4, characterized in that the closing element (42) can be brought automatically into a second open position in which a container opening (44) of the collection container (8) is open when the first fasteners (60) of the connection device (50) are connected to first counter-fasteners (62) of the collection container (8).

6. Processing arrangement according to claim 5, characterized in that the first fasteners (60) and the first counter-fasteners (62) form a first slide-in connection (64) and the closing element (42) is designed in the shape of a slide and can be displaced from the closed position into the second open position by a sliding-in movement of the first fasteners (60) relative to the first counter-fasteners (62).

7. Processing arrangement according to any one of claims 1 to 6, characterized in that the processing container (52) has a closing element (72) which can be adjusted between a final position in which it closes the mixing receptacle (74) and a receiving position in which the mixing receptacle (74) is open, wherein preferably the closing element (72) can be brought automatically into the receiving position when the second fasteners (66) of the connection device (50) are connected to second counter-fasteners (68) of the processing container (52).

8. Processing arrangement according to claim 7, characterized in that the second fasteners (66) and the second counter-fasteners (68) form a second slide-in connection (70) and the closing element (72) is formed by a closure slide which can be displaced by a slide-in movement of the second fasteners (66) relative to the second counter-fasteners (68) from the final position into the receiving position.

9. Processing arrangement according to any one of claims 1 to 8, characterized in that the processing device (58) has, in addition to the processing receptacle (56) for the connection device (50) with collection container (8) and processing container (52) attached thereto, at least one drive (86; 92) and the drive (86; 92) in a receiving position forms a first drive connection (88) with the mixing tool (84), wherein preferably the at least one drive (86; 92) in the receiving position also forms a second drive connection (94) with the comminuting tool (82).

10. Processing arrangement according to any one of claims 1 to 9, characterized in that the collection container (8) has a piston (100) for emptying the collection receptacle (34) in the direction of the passage opening (80).

11. Processing arrangement according to any one of claims 1 to 10, characterized in that the processing container (52) has a closable input / output connection (78).

12. Processing arrangement according to claim 11, characterized in that a slide (104) for emptying the mixing receptacle (74) via the input / output connection (78) is provided on the processing container (52).

13. Processing arrangement according to any one of claims 10 to 12, characterized in that the processing device (58) has at least one actuator (98; 102) for actuating the piston (100) and / or the slide (104), wherein the processing device (58) in particular has an electronic device (106) for at least partially automated activation of the at least one drive (86; 92) and / or the at least one actuator (98; 102).

14. Processing arrangement according to any one of claims 1 to 13, characterized in that a camera (110) is provided on the processing device (58) for the visual recording of the mixing receptacle (74).

15. Collection / processing system comprising a processing arrangement according to any one of claims 1 to 14, characterized in that the collection container (8) can be detachably fixed to a connection housing (32) of a collection device (10) which is arranged for separating and collecting tissue material (G) from a fluid flow (F) between a tissue removal device (12) and a vacuum device (28).

16. Collection / processing system according to claim 15, characterized in that the collection container (8) forms a flow portion (36) of a connection path (22) between a shaver-side flow connection (14) which can be fluidically connected to the tissue removal device (12) and a vacuum-side flow connection (24) which can be fluidically connected to the vacuum device (28).

17. Collection / processing system according to claim 15 or 16, characterized in that the closing element (42) of the collection container (8) can be brought automatically from a first open position into the closed position when the collection container (8) is removed from the connection housing (32).