HEMOSTATIC DEVICE AND METHOD
Patent Information
- Application Number
- DE602020053470
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2019-08-19
- Filing Date
- 2020-06-25
- Publication Date
- 2025-06-25
- Estimated Expiration
- 2040-06-25
AI Technical Summary
Existing hemostatic agents for bone bleeding, such as bone wax, water-soluble alkylene oxide copolymers, and soft tissue hemostats, pose issues like prolonged presence at the surgical site, inflammation, infection risk, delayed bone healing, and thermal injury, while synthetic alternatives like fibrin sealants are expensive and not well-suited for bone hemostasis.
A synthetic hemostatic agent composed of porous calcium compounds, such as calcium phosphate and calcium sulfate, in granular form with interconnected pores, designed to promote hemostasis by containing at least 10% inorganic calcium ions and having a porosity of 40-90%, with granules sized 0.1-2.5 mm and pores of 30-300 µm, enhancing bone bleeding control.
The calcium-based hemostatic agent effectively reduces bone bleeding during and after surgery, minimizing surgical complications and promoting bone healing without the drawbacks of organic or animal-derived materials, as demonstrated by clinical trials in open heart surgeries.