METHOD AND DEVICE FOR ANTI-AGING COSMETIC SKIN TREATMENT BY PHOTOMODULATION, IONTOPHORESIS AND VIBRATIONS
The combination of photomodulation with specific light wavelengths and iontophoresis with micro-vibrations addresses the inadequacies of existing anti-aging treatments, achieving substantial reductions in facial redness, pigmentation, and wrinkles.
Patent Information
- Application Number
- FR2015000791
- Authority / Receiving Office
- FR · FR
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2015-04-15
- Publication Date
- 2026-01-16
- Estimated Expiration
- 2035-04-15
AI Technical Summary
Existing anti-aging cosmetic treatments are inadequate in effectively reducing facial redness, pigmentation, and wrinkles, with existing devices failing to provide significant and consistent improvements.
A combination of photomodulation using specific wavelengths of light (630 nm, 525 nm, and 590 nm) and iontophoresis with micro-vibrations, along with the application of an anti-aging cosmetic composition, to stimulate skin cells and enhance ingredient penetration, is employed.
The treatment significantly reduces facial redness by 52%, lightens pigmented lesions by up to 90%, and decreases wrinkles by 30-72% within a month, demonstrating excellent skin tolerance and efficacy.
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Abstract
Description
Excellent results were obtained one hour after a single exposure to 630 nm light, and with repeated exposure once a day for 28 days to 596 nm light, and for two months once a day to 525 nm light. Selecting a combination of three different wavelength ranges and an appropriate light intensity yielded a surprising result, as demonstrated by the analyses described below. Finally, ion therapy preceded by the application of an anti-aging cosmetic composition and micro-vibrations associated with light exposure to the 3 ranges of wavelengths described allow for even more interesting results. Example 1: Clinical evaluation on 25 subjects of an anti-aging cosmetic treatment using a device emitting light at a wavelength of 630 nm. A treatment using a device emitting light at wavelengths of 630 nm was performed on one half of the face on 25 healthy subjects (Caucasian women aged 23 to 68 years with a mean age of 49.40 ± 10.64 years). a) Creation of a model of facial erythema after mesotherapy Performing a mesotherapy session using a roller with 1 mm long needles combined with the application of a polyrevitalizing solution. This roller allows the stimulation of skin cells in response to the mechanical aggression of the needles and the creation of micro-channels optimizing the penetration of active ingredients. In the immediate aftermath and generally continuing for 30 minutes after the mesotherapy session, significant erythema is observed on the cheeks, extending onto the chin and forehead. b) Performing the 630 nm light application session on the right side of the face To quantify the anti-redness effect, each treatment session was performed with a device emitting continuous red light at 630 nm for 3 minutes on the right side of the face. Chromametric evaluations combined with dermatological scoring were used to measure the modulation of skin redness. 3D photographs illustrate the effect of the device according to the invention. c) Analyses at T0, after mesotherapy, 30 minutes and one hour after the session with the device according to the invention * Dermatological analysis, using a scoring system (0 to 5) based on photographs taken with the LifeViz II device by selecting the option to visualize the red components of the skin (erythema, rosacea, vascular disease...). * Chromametric analysis of skin color using parameter a: red of the Konica Minolta CR / DP-400® Chromameter. A decrease in parameter (a) correlates with a decrease in erythema. * 3D photographs (profile) using the LifeViz II device allowing visualization of the modulation of erythema after treatment. d) RESULTS This mesotherapy model significantly and identically increased erythema in both cheeks with an average score of 2.88 versus 0.37 (p=4.66x10-9) for the right cheek and 2.76 versus 0.24 for the untreated left cheek (p=3.14x10-9). The erythema observed on the right cheek treated by the device according to the invention emitting light at 630 nm is significantly reduced compared to the untreated left cheek with a mean score of 1.36 versus 2.08 (p= 0.00076). The anti-redness effect obtained by the device according to the invention emitting light at 630 nm is 52%. d) CONCLUSION In this clinical trial conducted on 25 subjects, using a mesotherapy-induced skin erythema model, a statistically significant reduction in redness was observed through dermatological and chromametric evaluation after treatment with the device according to the invention, which emits light at 630 nm. The anti-redness effect of the device according to the invention, emitting light at 630 nm, was 52% after mesotherapy. This effect could likely be extended to other inflammatory skin conditions such as sunburn and skin irritations in subjects with sensitive skin. Skin tolerance after use of the device according to the invention, emitting light at 630 nm, was excellent for all subjects. The device according to the invention for implementing the cosmetic treatment process according to the invention thus makes it possible to significantly reduce redness in an area of the skin. Example 2: Clinical evaluation on 30 subjects of an anti-aging cosmetic treatment using a device emitting light at a wavelength of 525 nm a) Selection criteria Treatment using a device emitting light at wavelengths of 525 nm was carried out on 30 subjects (23 women and 7 men) with pigmented spots (lentigines) on the face, back of hands or décolleté, aged 43 to 71 years, with an average age of 54.4 ± 9.3 years. The topography of the lentigines selected as the target area for evaluation was the back of the hands in 25 cases, the face in 4 cases and the décolleté in 1 case. b) Performing the session of applying light at 525 nm to the pigmented lesions. Each subject underwent a treatment session with the device, emitting in continuous mode at 525 nm for 2 minutes, for 2 months on each selected pigmented lesion. The device was placed a few centimeters from the skin or in contact with the skin. Treatment of facial lesions was performed before makeup was applied. c) Results In this clinical study, a highly statistically significant decrease in lentigine pigmentation was observed at day 30, with a mean score of 1.54 versus 2.21 at day 0 (p = 2.10-11), representing a 30.3% reduction. The maximum pigmentation reduction score was 75% for some subjects. The reduction in lentigo pigmentation was confirmed at day 60 with a mean score of 1.19 versus 2.21 at day 0 (p = 3.5 x 10⁻¹⁴), representing a 46% reduction. The maximum score for lentigo pigmentation reduction was 90% in some cases. All subjects experienced a reduction in pigmentation and the surface area of the spots and were satisfied with the treatment. The device was deemed easy to use in all cases. The device's tolerance was excellent in all cases. d) Conclusion In this clinical trial conducted on 30 subjects, we demonstrated a significant lightening of lentigo-type pigmented lesions on the backs of the hands or face: After 30 days of treatment with LEDs (Light Emitting Diodes from the laboratory) Using Talika) emitting at 525 nm, we observed an average score of 1.54 versus 2.21 (at JO), representing a decrease of 30.3%. The maximum pigmentation reduction score was 75%. After 60 days, we observed an average score of 1.19 versus 2.21 at day 0, representing a 46% decrease. The maximum score for reducing lentigine pigmentation was 90% in some cases. These results obtained on lentigines suggest a similar depigmenting effect on melasma and an increase in skin radiance after treatment with green LEDs (525 nm). It can also be used preventively to avoid the progressive repigmentation of lentigines after destruction by laser or IPL (flash lamps). The device according to the invention for implementing the cosmetic treatment process according to the invention thus makes it possible to significantly reduce the pigmentation of skin spots. Example 3: Clinical evaluation on 30 subjects of an anti-aging cosmetic treatment using a device emitting light at a wavelength of 590 nm The clinical study included a total of 30 women aged 35 to 60 years, the average age being 45 years (37 to 59). a) Performing the session of applying light at 590 nm to pigmented lesions in the wrinkles of the paw or the suborbital region. The device was used daily, preferably at the same time of day (45-second pulsed sessions), on crow's feet or the area under the eyes for four weeks. Two visits were scheduled: one on day 0 for inclusion and one on day 28 (closing visit). At each visit, a dermatological clinical examination was performed to assess skin tone (texture analysis) and the presence of wrinkles or fine lines (semi-quantitative scores). Macrophotographs (subject without makeup, standard poses) were taken. Measurements of wrinkle surface area, depth, and skin roughness were taken on days 0 and 28 using a measuring device (Skin Station). An assessment of the tolerance and cosmetic comfort as well as the effectiveness of the product was collected. b) Results • The mean clinical skin tone score was 1.93 at day 0. It was 1.57 at day 28, corresponding to a statistically significant 18% improvement in skin tone. • The mean clinical score for fine lines and wrinkles was 2.13 at day 0. It was 1.73 at day 28, representing a statistically significant decrease of 19%. • The average percentage of surface area occupied by fine lines and wrinkles, calculated by the Skin Station, was 5.76% at day 0. It was 3.66% at day 28, representing a statistically significant decrease of 36.4%. • The average roughness of the crow's feet and periorbital area, calculated by the Skin Station, was 0.479 at day 0. It was 0.391 at day 28, representing a statistically significant decrease of 18.4%. • The average volume of fine lines and wrinkles (V / mm²), calculated by the Skin Station, was 57.5 at day 0. It was 40.2 at day 28, representing a statistically significant decrease of 30%. The largest decrease in the volume of fine lines and wrinkles was 72%, and the smallest among responding subjects was 15%. Tolerance was excellent and no adverse effects were observed. c) Conclusion Clinical improvement after treatment with the device was observed in 27 of the 30 subjects. The results of the open-label clinical study on 30 women who applied the device daily to the crow's feet and under-orbital area for 28 days demonstrate an average improvement of 18% and 19% in clinical scores for skin tone and wrinkle appearance, respectively. The surface area of wrinkles and fine lines was reduced by 36.4% and their volume by 30% (measurements taken using the Skin Station). The product was very well tolerated and the overall cosmetic assessment was very good. The device according to the invention for implementing the cosmetic treatment process according to the invention thus makes it possible to significantly reduce skin wrinkles.
Claims
Demands 15 20 1. A cosmetic anti-aging skin treatment process, characterized in that it comprises: a. a step of exposing said area of skin to be treated to a light source (20) emitting light whose wavelength spectrum is between 590 and 598 nm, for a light intensity between 8000 and 12000 mcd and for a determined period, b. an exposure step of said area of skin to be treated to a light source (20) emitting light at a wavelength between 515 and 535 nm, preferably 525 nm, for a light intensity between 8000 and 12000 mcd and for a specified period, c. a step of exposing said area of skin to be treated to a light source (20) emitting light whose wavelength spectrum is between 630 and 660 nm, for a light intensity between 8000 and 12000 mcd and for a specified period, and d. concomitantly with at least one of steps a), b) and c) a step of exposure of said area of skin to be treated to ion therapy and which shall be preceded by the application of a topical composition comprising an anti-aging active, said ion therapy step being advantageously carried out by the application of an electric current of 700pA to said area of skin to be treated having previously received the application of said topical composition; e. concomitantly with at least one of the steps a) b) c) a step of exposing said area of skin to be treated to microvibrations between 700 and 950 hz. 30 2. A cosmetic treatment process according to claim 1, characterized in that said light, whose wavelength spectrum is between 590 and 598 nm, is emitted in the form of bursts of light pulses.
3. Cosmetic treatment method according to claim 2, characterized in that the frequency of said pulses is approximately 5 Hz and the duration of said pulses is approximately 1 ms.
4. Cosmetic treatment method according to any one of the preceding claims, characterized in that each determined period is between 30 seconds and 3 minutes.
5. A cosmetic treatment method according to any one of the preceding claims, characterized in that said exposure steps are repeated every day for two weeks.
6. Device (1) for an anti-aging cosmetic treatment of an area of the skin according to the method according to any one of claims 1 to 5, said device comprising a housing including a light source (20), characterized in that said light source (20) emits alternately or concomitantly, preferably alternately, light in a spectrum of wavelengths between 590 and 598 nm, with a luminous intensity between 8000 and 12000 mcd, light at a wavelength between 515 and 535 nm, preferably 525 nm, with a luminous intensity between 8000 and 12000 mcd, and light in a. spectrum of wavelengths between 630 and 660 nm, with a light intensity between 8000 and 12000 mcd, an iontophoresis device and a motor to create microvibrations between 700 and 950 hz.
7. Device (1) according to claim 6, characterized in that said light source (20) comprises a plurality of light-emitting diodes (210), preferably 29 diodes, more preferably 29 multifunction diodes.
8. Device (1) according to any one of claims 6 or 7, characterized in that it comprises a detector (D) enabling it to automatically activate, upon contact with the skin, the ion therapy and microvibration stages between 700 and 950 Hz.