CARTOUCHE LED

Abstract

LED CARTRIDGE Cartridge for skin treatment and transdermal delivery, comprising a microneedle plane including one or more microneedles, configured to prepare the skin for treatment, a light source configured to apply light treatment, one or more sensors configured to measure one or more cartridge data points, and a chip configured to collect one or more cartridge data points. In addition, an applicator comprising a cartridge configured to removably couple to the applicator, including a microneedle plane including one or more microneedles, configured to prepare the skin for microneedle treatment, a light source configured to apply light treatment, one or more sensors configured to measure one or more cartridge data points, and a chip configured to collect one or more cartridge data points.Figure for the abridged version: none.

Description

Title of the invention: LED CARTRIDGE SUMMARY

[0001] A cartridge for skin treatment and transdermal delivery, comprising a microneedle plane including one or more microneedles, configured to prepare the skin to provide a treatment, a light source configured to apply a light treatment, one or more sensors configured to measure one or more cartridge data points and a chip configured to collect the one or more cartridge data points, is disclosed herein.

[0002] In some embodiments, the chip is a near-field communication (NFC) tag. In some embodiments, the chip is a microcontroller unit (MCU) tag. In some embodiments, the chip is an optical recognition sensor. In some embodiments, the chip is an optical recognition sensor.

[0003] In some embodiments, the cartridge further includes a cap configured to cover one or more microneedles. In some embodiments, the one or more sensors are a humidity sensor, a pressure sensor, a temperature sensor, an optical sensor, or a combination thereof.

[0004] In some embodiments, one or more cartridge data points are a change in skin moisture, a cartridge pressure level, a change in skin temperature, a change in skin color, or a combination thereof.

[0005] In some embodiments, one or more microneedles are arranged in a grid on the microneedle plane. In some embodiments, the light source is located at the center of the microneedle plane. In some embodiments, the light source is configured to apply blue light, red light, or near-infrared (NIR) light.

[0006] Also disclosed herein is an applicator comprising a cartridge configured to removably couple to the applicator, including a microneedle plane comprising one or more microneedles, configured to prepare the skin to deliver microneedle treatment, a light source configured to apply light treatment, one or more sensors configured to measure one or more cartridge data points, and a chip configured to collect the one or more cartridge data points.

[0007] In some embodiments, the applicator includes a spring disposed inside an interface of the applicator and a cap configured to couple to the cartridge, where the spring and the cap together comprise a torsion push mechanism configured to couple and remove the cartridge from the applicator.

[0008] In some embodiments, the applicator further includes a cap configured to cover one or more microneedles. In some embodiments, the chip is a near-field communication (NFC) tag. In some embodiments, the chip is a microcontroller unit (MCU) tag.

[0009] In some embodiments, one or more sensors are a humidity sensor, a pressure sensor, a temperature sensor, an optical sensor or a combination thereof.

[0010] Also disclosed herein is a method for safely applying a microneedle treatment to the skin, the method comprising bringing the skin into contact with a microneedle plane of an applicator, preparing the skin with one or more microneedles, applying a light treatment with a light source and measuring one or more cartridge data with one or more sensors on the cartridge.

[0011] In some embodiments, the method further includes the application of the light treatment simultaneously with the skin preparation. In some embodiments, the light treatment includes blue light treatment. In some embodiments, the light treatment includes red light treatment. In some embodiments, the light treatment includes near-infrared (NIR) light treatment.

[0012] This summary is intended to present a selection of concepts in a simplified form, which are described in greater detail below in the detailed description. This summary is not intended to identify key features of the claimed subject matter, nor is it intended to be used as an aid in determining the scope of the claimed subject matter. Description of the drawings

[0013] The foregoing aspects and many related advantages of this invention will be more readily appreciated as they are better understood with reference to the following detailed description, when taken in conjunction with the accompanying drawings, in which:

[0014] [Fig.1A] Fig.1A is a perspective view of an example of an applicator in accordance with the present technology;

[0015] [Fig.1B] The [Fig.1B] is an example of a cross-sectional view of the applicator of the [Fig.1A], according to the present technology;

[0016] [Fig 2A-2B] FIGURES 2A-2B are rear views of an example applicator, with and without refill system, in accordance with the present technology;

[0017] [Fig.3] The [Fig.3] is a perspective view of an example of an applicator in accordance with the present technology;

[0018] [Fig.4A] The [Fig.4A] is a perspective view of an example of an applicator in accordance with the present technology;

[0019] [Fig.4B] The [Fig.4B] is a cross-sectional view of the example applicator of the [Fig.4A], in accordance with the present technology;

[0020] [Fig.5] The [Fig.5] is an example of an applicator, in accordance with the present technology;

[0021] [Fig. 6] Fig. 6 is an example of a dispensing device in accordance with the present technology; and

[0022] [Fig.7] The [Fig.7] is an example of a method 600 of radiotherapy application in accordance with the present technology. Detailed description

[0023] Microneedling is a cosmetic procedure that stimulates collagen production using small, sterilized needles. It can help smooth, firm, and tone the skin and improve the appearance of scars, acne, and wrinkles. In addition, LED (light-emitting diode) light therapy is a non-invasive treatment that penetrates the skin layers to improve the skin. LED light therapy treats various skin conditions and problems, such as acne, fine lines, and psoriasis. It comes in different types, including red LED light therapy, blue LED light therapy, ultraviolet (UV) light therapy, and near-infrared (NIR) light therapy, which are sometimes used in combination.

[0024] Applicators, systems, and methods for microneedle therapy are disclosed herein. In some embodiments, the applicator includes a removable cartridge having a microneedle plane with one or more microneedles. The cartridge may also include a chip configured to collect data from one or more sensors located on the cartridge. In some embodiments, the one or more sensors may include a light source, such as an LED light source, configured to deliver light therapy. In some embodiments, the light therapy may be administered sequentially or simultaneously with the microneedle therapy.

[0025] Figure 1 is a perspective view of an example of applicator 100, according to the present technology. In some embodiments, The applicator 100 includes a body 105, a fastener 120, an applicator surface 110, and a label 115. In some embodiments, the applicator further includes an interface 120 configured to couple to a removable cartridge 125. In some embodiments, the carriage 322 can be removably coupled to the track. In this way, the cartridge 125 can be removed for cleaning or replaced to ensure that the cartridge 125 is hygienic.

[0026] In some embodiments, the body 120 is substantially cylindrical, but the body 120 can have any form factor. In some embodiments, the body 120 is longer than it is wide, to allow a user to hold the body 120 like a writing instrument. In some embodiments, the body 302 is cylindrical, as shown in [Fig. 1A]. In some embodiments, the body 120 has a first end including an electrical port 107, and a second end configured to couple with the removable cartridge 120.

[0027] In some embodiments, the electrical port 107 is electrically coupled to a battery (as illustrated and described in [Fig. 1B]) located inside the applicator 100. In some embodiments, the electrical port 107 is configured to facilitate an electrical connection between the battery and a charging device or outlet. In some embodiments, this can be facilitated by a cable or wire. In some embodiments, the electrical port 107 powers the applicator 100. In some embodiments, the electrical port 107 can charge the battery of the applicator 100, and the device can operate even when not connected to an outlet or charging device.

[0028] In some embodiments, the applicator 100 includes a body 105. In some embodiments, the button 110 is configured to turn the applicator 100 on and / or off. In some embodiments, the button 110 can be used to facilitate a wireless connection (such as Bluetooth™, Wi-Fi, or Zigbee) with another device, such as a smart device (as shown and described in [Fig. 7]). In some embodiments, the button 110 can start or stop therapy, as described herein.

[0029] In some embodiments, the actuator 112 can start or stop the therapy (also referred to herein as microneedle therapy or microneedle treatment), as described herein. In some embodiments, the actuator 112 can increase or decrease the intensity of the therapy. In some embodiments, the actuator 112 may be a button, a touch-sensitive capacitive button, a switch, or similar.

[0030] During operation, the applicator 100 is charged or powered by the electrical port 107. In some embodiments, the button 110 can be pressed or operated to turn on the applicator 100. In some embodiments, a user can The user places a microneedle plane (such as microneedle plane 130, as shown in [Fig. 1B]) on their skin. In some embodiments, the user can then press or otherwise actuate the actuator 112 to begin microneedle therapy while moving the applicator 100 over their skin. In some embodiments, the tip 925 includes one or more grooves as shown in [Fig. 6]. As the user moves the applicator 100 over their skin, the one or more microneedles prepare the user's skin to deliver the microneedle treatment. As used here, the term "prepare" means to penetrate the skin, exfoliate the skin, or otherwise break the skin barrier.

[0031] Figure 1B shows an example of a cross-sectional view of the applicator 100 of Figure 1A, according to the present technology. As explained above, in some embodiments, the applicator 100 includes an electrical port 107, a button 110, a body 105, and an actuator 115. In some embodiments, the applicator 100 further includes a label 115.

[0032] In some embodiments, the power source 170 is a battery, a capacitor, or similar. In some embodiments, the battery 121 is charged with a wired connection via the electrical port 107. The battery 121 can power the applicator 100.

[0033] In some embodiments, the cartridge further includes an interface 120 configured to couple to a removable cartridge 125. In some embodiments, the interface 120 houses a spring 140, a cap 123, and a pin 127. In some embodiments, the applicator 100 includes a body 105. In some embodiments, the cartridge 125 houses a secondary spring 129. In some embodiments, the cartridge includes a microneedle plane 130. In some embodiments, the cartridge 125 contains the secondary spring and the pin 127. In some embodiments, the spring 140 and the secondary spring 129 work in tandem to remove and / or couple the cartridge 125 to the applicator 100, as illustrated and described in more detail in Figures 2A-2B. In some embodiments, the cartridge 125 is coupled to a microneedle plane 130 including one or more microneedles (as shown in [Fig.6]. In some embodiments, the insert 220 is configured to couple to the pot 235. In some embodiments, the spring 140 and the cap 123 together comprise a torsional push mechanism configured to couple and remove the cartridge 125 from the applicator 100. During operation, when the cartridge 125 is pushed towards the cap 123, the secondary spring 129 is compressed. At the same time, the spring 140 is compressed and allows the cartridge 125 to couple and / or interlock with the cap 123 to retain the cartridge 125 in the interface 120.

[0034] [Fig.2A]-2B are close-up views of an example of applicator 100 with a Removable cartridge 125, according to this technology. In some embodiments, the applicator 100 includes an interface 120 configured to couple with the cartridge 125. In some embodiments, the cartridge 125 is configured to couple with the interface 120 by means of a "twist-locking mechanism," which may include a spring (such as spring 140) and a plug (such as plug 123). During operation, a user presses on the cartridge 125 and rotates it to release it from the interface 120. To couple the cartridge 125 with the interface 120, the user can push the cartridge 125 into the interface 120 and rotate it. In such embodiments, the cartridge 125 engages with the plug (such as plug 123), which retains the cartridge 125.

[0035] Figure 1 is a perspective view of an example of an applicator 100, according to the present technology. In some embodiments, the applicator 100 includes a body 105. In some embodiments, the cap 135 is transparent or otherwise clear. In such embodiments, the cap 135 is configured to allow a user to see the microneedle plane 130 through the cap 135. In other embodiments, the cap 135 is opaque. In some embodiments, the cap 135 is cylindrical, but the cap 135 can be any shape or form factor. In some embodiments, the cap 135 is made of plastic, glass, metal, or the like. In some embodiments, the housing is configured to contain a communication device (as shown in [Fig. 6]) on the microneedle plane 130.This can prevent one or more microneedles from bending, being damaged, and / or becoming contaminated. In some embodiments, the cap keeps the microneedles of the microneedle tray 130 clean and hygienic. In some embodiments, the cap 135 is also replaceable. During operation, a user can remove the cap 135 from the cartridge 123 before applying the microneedle treatment to their skin. In some embodiments, the cap 135 and / or the light source (such as the light source 170) are configured to emit light with a peak emission in the ultraviolet (UV) light range. In this way, when the cap 135 is placed on the applicator 100, the UV light is emitted to sterilize the microneedle tray 130.

[0036] Figure 1 is a perspective view of an example of an applicator 100, according to the present technology. In some embodiments, the applicator 100 includes a cartridge 125 with a microneedle plane 130. In some embodiments, the cartridge 125 houses a secondary spring 129 and a pin 127. In some embodiments, the cartridge 125 is coupled to removable way to an interface 120 of the applicator 100. In some embodiments, the interface 120 houses a spring 140 and a cap 123.

[0037] In some embodiments, the applicator 100 further includes a label 115. In some embodiments, the chip 145 is configured to collect and / or transmit one or more data points from the cartridge 120 to an external device or an intelligent device. In some embodiments, the applicator further includes one or more sensors (as shown in Figures 4). In some embodiments, each sensor in the sensor system is configured to transmit data to the chip 145. In some embodiments, the one or more sensors include at least one position sensor and status sensors. In some embodiments, the optical system 310 is a single camera 315.

[0038] Figure 4B is chip 145 of applicator example 100 of Figure 4A, according to the present technology. In some embodiments, chip 145 is a near-field communication (NFC) beacon. In some embodiments, chip 145 is a microcontroller unit (MCU) beacon. Chip 145 can communicate with an external device, such as a smart device (as shown in Figure 7). In some embodiments, chip 145 transmits one or more data points to the external device. In some embodiments, the one or more data points can be used to create a treatment plan, monitor how the treatment is applied, instruct a user to apply a treatment, prevent a treatment, and similar functions.

[0039] Figure 1A is an example of an applicator 100 according to the present technology. In some embodiments, the cartridge 125 includes a sensor system. In some embodiments, the sensor system includes at least one pressure sensor 160, one humidity sensor 150, or one temperature sensor 155. In some embodiments, the sensor system includes a pressure sensor 160, a humidity sensor 150, a temperature sensor 155, or a combination thereof.

[0040] During operation, the user can move the cartridge 125 over the user's skin S, as indicated by the arrow. In some embodiments, the sensor system is configured to collect and monitor data, such as the pressure a user applies to the cartridge, the user's skin temperature, and / or the user's skin moisture. In some embodiments, the moisture sensor 150 and the temperature sensor 155 (and / or the thermal coupler 165) measure skin moisture and skin temperature for feedback control during the microneedling therapy. For example, if the moisture sensor detects high moisture on the user's skin and / or if the temperature sensor detects high skin temperature, The applicator 100 or an external device (such as the smart device 200 in [Fig. 7]) can reduce the intensity of the microneedling treatment or even stop it. In some embodiments, the combination of the moisture sensor 150 and the thermal sensor (and / or the thermal couple 165) is used to measure a user's transepidermal water loss (TEWL).

[0041] In some embodiments, the applicator 100 (or an intelligent device, such as the intelligent device 200) has a pressure threshold. In some embodiments, if the pressure measured by the pressure sensor 160 exceeds the pressure threshold, the applicator 100 or an external device alerts the user to reduce the pressure. In some embodiments, when the pressure exceeds the pressure threshold, the microneedling treatment is stopped. A chip (such as the chip 145) can transmit one or more data points from the humidity sensor 150 and / or the temperature sensor 155 to the external device. In this way, the applicator 100 can prevent a user from injuring themselves by applying microneedling therapy at an increased frequency and / or above the pressure threshold. The external device can use the one or more data points in various ways, as described herein.

[0042] Figure 6 is an example of a flexible substrate 100, in accordance with the present technology. In some embodiments, the microneedle plane 130 includes a plurality of microneedles 175A, 175B, 175C... 175N. In some embodiments, the plurality of nozzles 150A, 150B, 150C are arranged in a grid. In some embodiments, the plurality of microneedles 175A, 175B, 175C... 175N are configured to penetrate to a depth of 3 mm into the skin. In some embodiments, the plurality of microneedles 175A, 175B, 175C... 175N are configured to penetrate to a depth of 10 µm into the skin. In some embodiments, the plurality of microneedles 175A, 175B, 175C... 175N are configured to exfoliate the skin but not penetrate it. As shown in [Fig. 6], in some embodiments, the optical sensor 170 is located at the center of the microneedle plane 130.

[0043] In some embodiments, the microneedle plane 130 further includes a light source 170, such as a light-emitting diode (LED). In some embodiments, the LED 170 is configured to deliver light therapy. In some embodiments, the LED 170 is configured to deliver blue, red, infrared (IR), and / or near-infrared (NIR) light therapy when the cartridge 125 is moved over a user's skin. In some embodiments, the light source 130 is configured to emit light having a peak emission that is in the visible spectrum, the near-infrared spectrum, the infrared spectrum, the UV spectrum, or a combination thereof. In some embodiments In realization, the light source 170 has a peak emission wavelength of 170 to 400 nm, 570-590 nm, 630 to 700 nm, 800 to 1200 nm, or a combination thereof.

[0044] Figure 6 is an example of a method 600 for applying radiotherapy according to the present technology. In some embodiments, the method 700 is carried out by means of a cartridge (such as cartridge 125) and / or an applicator (such as applicator 100). In some embodiments, the cartridge includes a microneedle plane (such as microneedle plane 130) comprising one or more microneedles (such as microneedles 175A, 175B, 175C... 175N). In some embodiments, the cartridge further includes an LED (such as LED 170). In some embodiments, the cartridge and / or applicator includes a chip (such as chip 145) configured to collect data from one or more sensors (such as humidity sensor 150, temperature sensor 155, thermal torque 165 and / or pressure sensor 160).

[0045] In block 705, the skin is in contact with the microneedle plane of the applicator. In some embodiments, a pressure sensor (which may be part of the sensor system) detects pressure applied to the skin. In some embodiments, the pressure data is transmitted to the applicator chip.

[0046] In block 710, the skin is prepared with one or more microneedles of the applicator. In some embodiments, the skin is penetrated to a depth not exceeding 5.0 mm. In some embodiments, the penetration of the skin with one or more microneedles is considered "microneedle therapy (or treatment)." In some embodiments, exfoliation but not penetration of the skin is considered "microneedle therapy (or treatment)."

[0047] In block 715, light therapy is applied with an LED on the cartridge. In some embodiments, the light therapy includes blue light therapy. In some embodiments, the light therapy includes red light therapy. In some embodiments, the light therapy includes near-infrared (NIR) light therapy. In some embodiments, blocks 710 and 715 occur simultaneously.

[0048] In block 720, one or more data points are measured using the sensor system (or one or more sensors) on the cartridge. In some embodiments, the one or more sensors include a temperature sensor, a pressure sensor, a humidity sensor, an optical sensor, and a combination thereof. In some embodiments, the data from each sensor is collected by the chip.

[0049] It should be understood that process 700 is to be interpreted as purely representative. In certain embodiments, the processing blocks of process 1100 may be carried out simultaneously, sequentially, in a different order, or even omitted, without departing from the scope of this disclosure.

[0050] This application may refer to quantities and numbers. Unless otherwise specified, these quantities and numbers are not to be considered restrictive, but rather representative of the possible quantities or numbers associated with this application. Similarly, in this regard, this application may use the term "plurality" to refer to a quantity or number. In this regard, the term "plurality" is understood to mean any number greater than one, for example, two, three, four, five, etc. The terms "about," "approximately," "near," etc., mean plus or minus 5% of the stated value. For the purposes of this disclosure, the expression "at least one of A, B, and C," for example, means (A), (B), (C), (A and B), (A and C), (B and C), or (A, B, and C), including all other possible permutations when more than three items are listed.

[0051] The embodiments disclosed herein may use circuitry to implement the technologies and methodologies described herein, operationally connect two or more components, generate information, determine operating conditions, control an apparatus, device, or process, and / or the like. Any type of circuitry may be used. In one embodiment, the circuitry includes, among other things, one or more computing devices such as a processor (e.g., a microprocessor), a central processing unit (CPU), a digital signal processor (DSP), an application-specific integrated circuit (ASIC), a field-programmable gate array (FPGA), or the like, or any combination thereof, and may include elements or electronics of separate digital or analog circuits, or combinations thereof.

[0052] An embodiment includes one or more data stores that, for example, store instructions or data. Non-limiting examples of one or more data stores include volatile memory (e.g., random access memory (RAM), dynamic random access memory (DRAM), and the like), non-volatile memory (e.g., read-only memory (ROM), electrically erasable and programmable read-only memory (EEPROM), compact disc with read-only memory (CD-ROM), and the like), persistent memory, or the like. Other non-limiting examples of one or more data stores include erasable and programmable read-only memory (EPROM), flash memory, or the like. One or more data stores may be connected, for example, to one or more computing devices by one or more instructions, data, or power buses.

[0053] In one embodiment, the circuitry includes a computer-readable media player or a memory slot configured to accept a signal-carrying medium (for example, computer-readable memory storage, computer-readable recording storage, or the like). In one embodiment, a program for causing a system to perform any of the disclosed processes may be stored, for example, on computer-readable recording storage (CRMM), a signal-carrying medium, or the like.Non-limiting examples of signal-carrying media include recordable media such as any form of flash memory, magnetic tape, floppy disk, hard disk drive, compact disc (CD), digital video disc (DVD), Blu-Ray disc, digital tape, computer memory, or the like, and transmission media such as digital and / or analog communication media (e.g., fiber optic cable, waveguide, wired communication link, wireless communication link (e.g., transmitter, receiver, transceiver, transmission logic, receiving logic, etc.).Other non-limiting examples of signal carrier media include, but are not limited to, DVD-ROM, DVD-RAM, DVD+RW, DVD-RW, DVD-R, DVD+R, CD-ROM, Super Audio CD, CD-R, CD+R, CD+RW, CD-RW, video compact discs, super video discs, flash memory, magnetic tape, magneto-optical disc, MINIDISC, non-volatile memory card, EEPROM, optical disc, optical storage, RAM, ROM, system memory, web server, or similar.

[0054] The detailed description presented above in relation to the accompanying drawings, where similar numbers refer to similar elements, is intended as a description of various embodiments of this disclosure and is not intended to represent the only embodiments. Each embodiment described in this disclosure is offered solely by way of example or illustration and should not be construed as being preferred or advantageous over other embodiments. The illustrative examples provided herein are not intended to be exhaustive or to limit the disclosure to the specific forms disclosed. Similarly, all the steps described herein may be interchangeable with other steps, or combinations of steps, to achieve the same or substantially similar result.In general, the embodiments disclosed here are not limiting, and the inventors contemplate that other embodiments within the scope of this disclosure may include structures and functionalities from more than one specific embodiment illustrated in the Figures and described in the memorandum.

[0055] In the preceding description, specific details are presented to provide a thorough understanding of the examples of embodiments of this disclosure. However, it will be apparent to a person skilled in the art that the embodiments of The implementations disclosed herein may be put into practice without incorporating all the specific details. In some cases, well-known process steps have not been described in detail in order to avoid unnecessarily obscuring various aspects of this disclosure. Furthermore, it should be noted that the implementations of this disclosure may employ any combination of the features described herein.

[0056] This application may include references to directions, such as "vertical", "horizontal", "front", "back", "left", "right", "top" and "bottom", etc. These references, and other similar references in this application, are intended to help describe and understand the particular embodiment (such as when the embodiment is positioned for use) and are not intended to limit this disclosure to those directions or locations.

[0057] This application may also refer to quantities and numbers. Unless otherwise specified, these quantities and numbers are not to be considered restrictive, but rather as examples of the possible quantities or numbers associated with this application. Similarly, in this respect, this application may use the term "plurality" to refer to a quantity or number. In this context, the term "plurality" is understood to mean any number greater than one, for example, two, three, four, five, etc. The terms "about," "approximately," etc., mean to within 5% of the stated value. The term "based on" means "based at least partially on."

[0058] The principles, representative embodiments, and modes of operation of this disclosure have been described in the preceding description. However, aspects of this disclosure that are intended to be protected should not be construed as being limited to the particular embodiments disclosed. Furthermore, the embodiments described herein should be considered illustrative rather than restrictive. It should be understood that variations and changes may be made by other means, and equivalents may be used, without departing from the spirit of this disclosure. Accordingly, it is expressly intended that all such variations, changes, and equivalents fall within the spirit and scope of this disclosure as claimed.

[0059] Although illustrative embodiments have been shown and described, it will be appreciated that various changes can be made to them without departing from the spirit and scope of the invention.

Claims

Demands

1. Skin treatment cartridge (125), comprising: - a microneedle plane (130) comprising one or more microneedles, configured to prepare the skin to provide a treatment; - a light source (170) configured to apply a light treatment; - one or more sensors configured to measure one or more cartridge data points; and - a chip (145) configured to collect the one or more cartridge data points.

2. Cartridge according to claim 1, wherein the chip (145) is a near field communication (NFC) tag.

3. Cartridge according to claim 1, wherein the chip (145) is a microcontroller unit (MCU) label.

4. Cartridge according to any one of claims 1 to 3, wherein the cartridge further comprises a cap (135) configured to cover one or more microneedles.

5. Cartridge (125) according to any one of claims 1 to 4, wherein one or more sensors are a humidity sensor, a pressure sensor, a temperature sensor, an optical sensor or a combination thereof.

6. Cartridge (125) according to any one of claims 1 to 5, wherein one or more cartridge data items are a change in skin moisture, a cartridge pressure level, a change in skin temperature, a change in skin color, or a combination thereof.

7. Cartridge according to any one of claims 1 to 6, wherein one or more microneedles are arranged in a grid on the microneedle plane (130).

8. Cartridge according to any one of claims 1 to 7, wherein the light source (170) is configured to apply blue light, red light or near-infrared (NIR) light.

9. Applicator (100) comprising: - a cartridge (125) configured to be removably coupled to the applicator, comprising: O a microneedle plan (130) comprising one or more microneedles, configured to prepare the skin to provide microneedle treatment; O a light source (170) configured to apply a light treatment; One or more sensors configured to measure one or more cartridge data points; and O a chip (145) configured to collect one or more cartridge data.

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