New complexes of iron (III) hydroxide with activated glucose syrups

Abstract

The invention relates to a method for the production of complexes of iron (III) hydroxide with activated glucose syrup and pharmaceutical compositions containing the complexes, wherein the molecular weight of the complex ranges from 115 to 140 kDa, preferably 120 to 130 kDa, as measured by high-performance liquid chromatography (HPLC - GPC) which comprises the following steps: 1) providing an aqueous solution of glucose syrup, having a dextrose equivalent (DE) of at least 30 to at most 50, preferably between 30 and 40, 2) hydrogen peroxide and optionally an oxidation catalyst are added to the solution of step (1), then the solution is cooled, so as to obtain the activated glucose syrup, 3) the aforementioned activated glucose syrup is converted into a complex with iron (III) hydroxide, 4) a complex of iron (III) hydroxide and activated glucose syrup is obtained, having more than two -COOH groups per glucose molecule.