Method for testing tertiary lymphoid tissue, and kit for testing tertiary lymphoid tissue

HK40135200APending Publication Date: 2026-07-17KYOTO UNIV

Patent Information

Authority / Receiving Office
HK · HK
Patent Type
Applications
Current Assignee / Owner
KYOTO UNIV
Filing Date
2026-06-08
Publication Date
2026-07-17

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Abstract

One purpose of the present disclosure is to provide a technique for testing the presence or absence of a tertiary lymphoid tissue in a subject without conducting biopsy. The method for testing the presence or absence of a tertiary lymphoid tissue in a subject comprises a step for measuring the concentration of glutathione in a bodily fluid sample collected from the subject.
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Description

Abstract One of the purposes of this disclosure is to provide a technique for examining the presence or absence of tertiary lymphoid tissue in a subject without biopsy. The method for examining the presence or absence of tertiary lymphoid tissue in a subject includes the step of measuring the glutathione concentration in a body fluid sample collected from the subject.

Claims

1. A testing method for determining presence or absence of a tertiary lymphoid tissue in a subject, the testing method comprising a step of measuring a glutathione concentration in a body fluid sample collected from the subject.

2. The testing method according to claim 1, wherein the body fluid sample is a urine sample.

3. The testing method according to claim 1 or 2, wherein the glutathione concentration is a reduced glutathione concentration.

4. The testing method according to claim 2, further comprising a step of measuring a creatinine concentration in the urine sample.

5. The testing method according to claim 1 or 2, wherein the subject is a kidney disease patient, a person in need of testing for presence or absence of kidney disease infection, or a person who has undergone kidney transplantation, the testing method being performed for testing presence or absence of a tertiary lymphoid tissue in a kidney.

6. A test kit for testing presence or absence of a tertiary lymphoid tissue in vivo, the test kit comprising a reagent for measuring a glutathione concentration.

7. Use of a reagent for measuring a glutathione concentration in manufacture of a test kit for testing presence or absence of a tertiary lymphoid tissue in a body.