Medical solution injection unit

Abstract

To provide a medical solution injection unit whose handling property and safety property are improved.SOLUTION: A medical solution injection unit 1 includes a tube 10. The tube 10 comprises: a center lumen 11; at least three puncture catheter ports 12a to 12c which communicate with the center lumen 11 and open at circumferentially different positions in the outer peripheral surface of the tube 10; and support mechanisms 40 which are disposed at positions respectively facing the at least three puncture catheter ports 12a to 12c with respect to the axis X of the tube 10, to support the tube 10.SELECTED DRAWING: Figure 2A

Description

[Technical field]

[0001] The present invention relates to a chemical liquid injection unit. [Background technology]

[0002] Conventionally, treatments, examinations, etc. have been performed by inserting catheter-like medical instruments into tubular organs of the human body, such as blood vessels and the digestive tract. In recent years, treatments have also been performed by injecting medical fluids into body tissues (treatment sites) using catheter-like medical instruments capable of injecting medical fluids. In treatments using catheters for injecting medical fluids, a puncture needle at the tip of a catheter that is delivered to the outside of the catheter tube through an opening or hole provided on the outer circumferential surface of the catheter tube is punctured into body tissues, and medical fluids are injected through the puncture needle. For example, Patent Document 1 discloses a medical fluid injection device in which a needle portion of a needle-like tubular body (catheter) is protruded from a protruding hole provided in one direction on the side of a tubular body (catheter tube) to puncture a specific tissue in the body, thereby injecting the medical fluid into the body tissue through the needle-like tubular body. [Prior art documents] [Patent documents]

[0003] [Patent Document 1] Patent No. 427905 Summary of the Invention [Problem to be solved by the invention]

[0004] When attempting to inject a liquid medicine into a specific body tissue as a treatment site using a catheter tube with a hole in one lateral direction as shown in Patent Document 1, it is necessary to rotate the catheter within the blood vessel according to the position of the body tissue. In addition, there is a risk that the catheter tube will move away from the blood vessel due to the repulsive force generated when the puncture needle is inserted into the body tissue, which raises safety concerns.

[0005] The present invention has been made in consideration of the above problems, and has an object to provide a chemical liquid injection unit with improved handling properties and safety. [Means for solving the problem]

[0006] In order to achieve the above-mentioned object, firstly, the present invention provides a drug solution injection unit including a long tube, the tube extending in the axial direction of the tube, a center lumen into which a puncture catheter having a puncture needle at its tip can be inserted, at least three puncture catheter ports communicating with the center lumen and opening at different circumferential positions on the outer circumferential surface of the tube, and a support mechanism arranged at a position opposite each of the at least three puncture catheter ports with respect to the axis of the tube and used to support the tube (Invention 1).

[0007] According to this invention (Invention 1), by selecting the puncture catheter port closest to the body tissue to which the medicinal liquid needs to be injected from among at least three puncture catheter ports and inserting the puncture catheter there, the medicinal liquid can be injected into the body tissue without rotating the catheter in the blood vessel. In addition, by using support mechanisms arranged at positions facing the at least three puncture catheter ports, it is possible to suppress the movement of the medicinal liquid injection unit in a direction away from the blood vessel due to the repulsive force generated when the puncture needle is inserted into the body tissue. In other words, according to this invention (Invention 1), it is possible to provide a medicinal liquid injection unit with improved handling and safety.

[0008] In the above invention (Invention 1), the support mechanism may include at least three support wire lumens extending in the axial direction of the tube, each into which at least one support wire can be inserted, and at least three support wire ports that communicate with each of the at least three support wire lumens and open at different circumferential positions on the outer circumferential surface of the tube (Invention 2).

[0009] According to this invention (Invention 2), a support wire port is selected that is positioned opposite the axis of the tube to the puncture catheter port from which the puncture catheter is delivered, and the support wire is delivered from this support wire port, thereby preventing the drug solution injection unit from moving away from the blood vessel due to the repulsive force generated when the puncture needle of the puncture catheter is inserted into the body tissue into which the drug solution needs to be injected.

[0010] In the above inventions (Inventions 1 and 2), the at least three puncture catheter ports may be arranged at equal intervals in the circumferential direction on the outer circumferential surface of the tube (Invention 3).

[0011] According to this invention (Invention 3), it is possible to appropriately select the puncture catheter port that is closest to the body tissue into which the medicinal liquid needs to be injected.

[0012] In the above inventions (Inventions 1-3), the at least three puncture catheter ports may be arranged at different positions in the longitudinal direction on the outer circumferential surface of the tube (Invention 4).

[0013] According to this invention (Invention 4), it is possible to more appropriately select the puncture catheter port closest to the body tissue to which the medicinal liquid needs to be injected.

[0014] In the above invention (Invention 4), the at least three puncture catheter ports may be arranged at equal intervals in the longitudinal direction on the outer circumferential surface of the tube (Invention 5).

[0015] According to this invention (Invention 4), it is possible to more appropriately select the puncture catheter port closest to the body tissue to which the medicinal liquid needs to be injected.

[0016] The above inventions (Inventions 1-5) may comprise a plurality of puncture catheter sets each including at least three puncture catheter ports, and the multiple puncture catheter sets may be arranged at different positions in the longitudinal direction of the tube (Invention 6).

[0017] According to this invention (Invention 6), it is possible to more easily inject medicinal liquid into multiple locations in body tissues where the medicinal liquid needs to be injected, without moving the medicinal liquid injection unit back and forth within the blood vessel.

[0018] In the above inventions (Inventions 1-6), a radiopaque marker may be disposed on at least a part of the outer periphery of each of the at least three puncture catheter ports (Invention 7).

[0019] According to this invention (Invention 7), the position of each puncture catheter port can be easily confirmed by X-ray.

[0020] In the above invention (Invention 1), the support mechanism may include a balloon member having a balloon (Invention 8).

[0021] According to this invention (Invention 8), a balloon member located opposite the puncture catheter port through which the puncture catheter is delivered and the axis of the tube is selected as a support mechanism, and by inflating the balloon of this balloon member, it is possible to prevent the drug solution injection unit from moving in a direction away from the blood vessel due to the repulsive force generated when the puncture needle of the puncture catheter is inserted into the body tissue into which the drug solution needs to be injected. Effect of the Invention

[0022] According to the present invention, the puncture needle can be inserted into a plurality of target sites without rotating the catheter in the blood vessel, and therefore, according to the present invention, a drug solution injection unit with improved handling properties and safety can be provided. [Brief description of the drawings]

[0023] [Figure 1] 1 is a schematic explanatory diagram showing a structure of a chemical liquid injection unit according to an embodiment of the present invention; [Figure 2A] 2 is a see-through perspective view that illustrates a part of a tube included in the liquid medicine injection unit of FIG. 1. FIG. [Figure 2B]2B is a diagram showing an example of a puncture catheter and a support wire inserted into the tube of FIG. 2A together with a blood vessel. FIG. [Figure 3A] FIG. 2B is a vertical projection of the tube of FIG. 2A relative to its axial direction. [Figure 3B] FIG. 2C is a vertical projection of the tube of FIG. 2B relative to its axial direction. [Figure 4A] FIG. 2B shows an example of placement of a radiopaque marker at the puncture catheter port of the tube of FIG. 2A. [Figure 4B] FIG. 2B shows another example of a radiopaque marker placed at the puncture catheter port of the tube of FIG. 2A. [Figure 5A] 13 is a see-through perspective view that illustrates a tube and a part of a tip portion of a liquid medicine injection unit of Modification 1. FIG. [Figure 5B] FIG. 5B is a diagram showing an example of a guide wire being inserted into the tube of FIG. 5A. [Figure 6A] 13 is a see-through perspective view that typically shows a part of a tube included in a liquid medicine injection unit of Modification 2. FIG. [Figure 6B] 6B is a diagram showing an example of a state where a puncture catheter and a support wire are inserted into the tube of FIG. 6A. FIG. [Figure 7A] FIG. 6B is a vertical projection of the tube of FIG. 6A relative to its axial direction. [Figure 7B] FIG. 6C is a vertical projection of the tube of FIG. 6B relative to its axial direction. [Figure 8] 13 is a see-through perspective view that typically shows a part of a tube included in a chemical liquid injection unit of Modification 3. FIG. [Figure 9] FIG. 13 is a schematic explanatory diagram showing the structure of a liquid medicine injection unit according to a fourth modified example. [Figure 10] 10 is a see-through perspective view that typically shows a part of a tube and a balloon member included in the liquid medicine injection unit of FIG. 9. [Figure 11] FIG. 10 is a vertical projection of the tube of FIG. 9 along its axial direction, along with a balloon member. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0024] Hereinafter, an embodiment of the present invention will be described with reference to the drawings. The present invention is not limited to the embodiment described below, and the described embodiment is merely an example for explaining the technical features of the present invention. Furthermore, the shapes and dimensions shown in each drawing are shown only to facilitate understanding of the contents of the present invention, and do not accurately reflect the actual shapes and dimensions.

[0025] FIG. 1 is a schematic explanatory diagram showing the structure of a drug solution injection unit 1 according to an embodiment of the present invention. The drug solution injection unit 1 includes a long tube 10. The drug solution injection unit 1 is a drug solution injection catheter used for injecting a drug solution into a specific body tissue that is a treatment site. The drug solution injection unit 1 is used, for example, to be inserted into a blood vessel of a heart that has developed a myocardial infarction and to inject cultured myocardial cells into a specific myocardium.

[0026] In this specification, the term "distal side" refers to a direction along the axial direction X of the tube 10 constituting the liquid injection unit 1, in which the liquid injection unit 1 advances toward a specific internal tissue that is a treatment site. The term "base end side" refers to a direction along the axial direction X of the tube 10 constituting the liquid injection unit 1, in the opposite direction to the distal side. The term "distal side" refers to a distal end of any member or site, and the term "base end" refers to a proximal end of any member or site. In FIG. 1, the left side of the figure is the "distal side" that is inserted into the body, and the right side of the figure is the "base end" that is operated by the operator.

[0027] As shown in FIG. 1, the liquid medicine injection unit 1 further includes a tip portion 20 connected to the tip end of the tube 10, and a branch socket 30 connected to the base end of the tube 10.

[0028] FIG. 2A is a perspective view showing a schematic view of a part of the tube 10 included in the liquid medicine injection unit 1 of FIG. 1. FIG. 2A generally corresponds to the part indicated by the symbol A in FIG. 1. As shown in FIG. 2A, the tube 10 includes a center lumen 11 extending in the axial direction X of the tube 10, at least three puncture catheter ports 12a to 12c opening at different circumferential positions on the outer peripheral surface 10s of the tube 10, and a support mechanism 40 disposed at positions facing the at least three puncture catheter ports 12a to 12c with respect to the axial direction X of the tube 10 and used to support the tube 10. The center lumen 11 is a lumen into which a puncture catheter Cp having a puncture needle at its tip can be inserted. The puncture catheter ports 12a to 12c are each connected to a common center lumen 11.

[0029] In this specification, "the support mechanism 40 disposed at a position facing each of the at least three puncture catheter ports 12a to 12c with respect to the axis X of the tube 10" means that, in a vertical projection view of the tube 10 with respect to the axis X direction, the support mechanisms 40 are disposed at a position facing each of the puncture catheter ports 12a to 12c with respect to the axis X of the tube 10. "The vertical projection view of the tube 10 with respect to the axis X direction" means a projection view of the tube 10 onto a plane perpendicular to the axis X of the tube 10.

[0030] In this embodiment, the support mechanism 40 includes at least three support wire lumens 13a-13c extending in the axial direction X of the tube 10, and at least three support wire ports 14a-14c opening at different circumferential positions on the outer peripheral surface 10s of the tube 10. The support wire lumens 13a-13c are each a lumen into which at least one support wire Ws can be inserted. The support wire ports 14a-14c are in communication with the support wire lumens 13a-13c, respectively.

[0031] Fig. 3A is a vertical projection view of the tube 10 in Fig. 2A in the axial direction X. As shown in Fig. 3A, in the vertical projection view of the tube 10 in the axial direction X, the center lumen 11 is located in the center so as to include the axis X of the tube 10. The support wire lumens 13a to 13c are disposed outside the center lumen 11 so as to surround the center lumen 11.

[0032] The inner diameter of the center lumen 11 is configured to be larger than the inner diameters of the support wire lumens 13a to 13c.

[0033] As shown in Fig. 3A, in a vertical projection view of the tube 10 in the direction of the axis X, the puncture catheter ports 12a-12c and the support wire ports 14a-14c are arranged at positions opposing each other with respect to the axis X of the tube 10. Note that "the puncture catheter ports 12a-12c and the support wire ports 14a-14c are arranged at positions opposing each other with respect to the axis X of the tube 10" means that the puncture catheter ports 12a-12c and the support wire ports 14a-14c may be arranged at positions generally facing each other with respect to the axis X, and is not necessarily intended to limit the arrangement to the puncture catheter ports 12a-12c and the support wire ports 14a-14c being arranged at positions directly opposing each other with respect to the axis X as shown in Fig. 3A. The opening center 14d of the support wire ports 14a to 14c may be located in a range in which the angle β defined by the imaginary straight line L passing through the opening center 12d of the puncture catheter ports 12a to 12c and the axis X and the axis X satisfies -45°≦β≦45°.

[0034] FIG. 2B is a diagram showing an example of the tube 10 of FIG. 2A when the puncture catheter Cp and the support wire Ws are inserted together with the blood vessel BV. FIG. 3B is a vertical projection of the tube 10 of FIG. 2B in the axial direction X. Note that the blood vessel BV is omitted in FIG. 3B. As shown in FIG. 2B and FIG. 3B, the liquid medicine injection unit 1 can select one of at least three puncture catheter ports 12a to 12c that is closest to the body tissue into which the liquid medicine needs to be injected, and insert the puncture catheter Cp thereto. The puncture catheter Cp has a puncture needle at its tip. This allows the liquid medicine to be injected into the body tissue without rotating the liquid medicine injection unit 1 in the blood vessel BV.

[0035] As shown in Figures 2B and 3B, in the drug solution injection unit 1, one of the puncture catheter ports 12a-12c from which the puncture catheter Cp is to be delivered is selected from the support wire ports 14a-14c and positioned opposite the axis X of the tube 10. The support wire Ws is delivered from that port and abutted against the inner wall of the blood vessel BV, thereby preventing the drug solution injection unit 1 from moving in a direction away from the blood vessel BV due to the repulsive force generated when the puncture needle of the puncture catheter Cp is inserted into the body tissue.

[0036] Two or more of the at least three support wire ports 14a to 14c may be selected as the support wire ports 14a to 14c from which the support wire Ws1 is delivered. That is, the support wire Ws may be delivered from each of two or more of the at least three support wire ports 14a to 14c to prevent the liquid injection unit 1 from moving in a direction away from the blood vessel BV. In addition, two or more support wires Ws may be delivered from one of the at least three support wire ports 14a to 14c to prevent the liquid injection unit 1 from moving in a direction away from the blood vessel BV.

[0037] As shown in Fig. 3A, the at least three puncture catheter ports 12a to 12c may be arranged at equal intervals in the circumferential direction on the outer peripheral surface 10s of the tube 10. In the example of Fig. 3A, the three puncture catheter ports 12a to 12c are arranged at equal intervals in the circumferential direction on the outer peripheral surface 10s of the tube 10 so that the angle α defined by the straight line L and the axis X is 120°. This makes it possible to more appropriately select one of the at least three puncture catheters 12a to 12c that is closest to the body tissue into which the medicinal liquid needs to be injected.

[0038] 2A, the at least three puncture catheter ports 12a to 12c may be disposed at different positions in the longitudinal direction on the outer peripheral surface 10s of the tube 10. This allows an appropriate selection of one of the at least three puncture catheter ports 12a to 12c that is closest to the body tissue into which the medicinal liquid needs to be injected.

[0039] The at least three puncture catheter ports 12a to 12c may be disposed at equal intervals in the longitudinal direction on the outer peripheral surface 10s of the tube 10. This makes it possible to more appropriately select one of the at least three puncture catheter ports 12a to 12c that is closest to the body tissue into which the medicinal liquid needs to be injected.

[0040] FIG. 4A is a diagram showing an example in which the X-ray opaque markers 15 are arranged on the puncture catheter ports 12a to 12c of the tube 10 in FIG. 2A. FIG. 4B is a diagram showing another example in which the X-ray opaque markers 15a to 15c are arranged on the puncture catheter ports 12a to 12c of the tube 10 in FIG. 2A. In the drug solution injection unit 1, the X-ray opaque markers 15a to 15c may be arranged on at least a part of the outer periphery of each of at least three puncture catheter ports 12a to 12c. This makes it possible to easily confirm the position of each of the puncture catheter ports 12a to 12c by X-ray. The X-ray opaque markers 15a to 15c may be arranged so that the position of each of the puncture catheter ports 12a to 12c can be confirmed by X-ray, and the arrangement method is not particularly limited. For example, as shown in FIG. 4A, the X-ray opaque markers 15a to 15c may be arranged so as to surround the outer periphery of the puncture catheter ports 12a to 12c. As shown in FIG. 4B, the X-ray impermeable markers 15a to 15c may be arranged linearly in the tangential direction of the outer periphery of the puncture catheter ports 12a to 12c.

[0041] The tip portion 20 has a tip opening 21. The tip opening 21 may be in communication with the center lumen 11. With this configuration, the guidewire Wg can be guided to the tip opening 21 of the tip portion 20 via the center lumen 11. That is, in the drug solution injection unit 1, the center lumen 11 may also serve as a guidewire lumen into which the guidewire Wg can be inserted.

[0042] The branch socket 30 is configured so that three connectors (not shown) can be attached. For example, the first and second connectors may be communicated to correspond to the center lumen 11, and the third connector may be communicated to the support wire lumens 13a to 13c. In this case, for example, the puncture catheter Cp inserted from the opening of the first connector can be guided to one of the puncture catheter ports 12a to 12c via the center lumen 11, and the guide wire Wg inserted from the opening of the second connector can be guided to the distal end opening 21 via the center lumen 11. Then, the support wire Ws inserted from the opening of the third connector can be guided to one of the support wire ports 14a to 14c via one of the support wire lumens 13a to 13c.

[0043] (Variation 1) FIG. 5A is a perspective view showing a schematic view of a tube 101 and a part of a tip portion 201 included in the liquid medicine injection unit 100 of the first modification. FIG. 5A generally corresponds to the part indicated by the symbol B in FIG. 1. FIG. 5B is a view showing an example when a guidewire Wg is inserted into the tube 101 of FIG. 5A. As shown in FIGS. 5A and 5B, the liquid medicine injection unit 100 may have a guidewire lumen 16 into which a guidewire Wg can be inserted, in addition to the center lumen 11. The guidewire lumen 16 extends in the axial direction of the tube 101 and communicates with the tip opening 21 of the tip portion 201. As shown in FIGS. 5A and 5B, a guidewire port 17 communicating with the guidewire lumen 16 may be disposed on the outer circumferential surface 101s of the tube 101. A plurality of guidewire ports 17 may be present at different positions in the circumferential direction of the tube 101. Each of the plurality of guidewire ports 17 may communicate with a common center lumen 11.

[0044] Regarding the three connectors (not shown) that can be attached to the branch socket 30, in the first modification, for example, a first connector may be connected to correspond to the center lumen 11, a second connector may be connected to correspond to the guidewire lumen 16, and a third connector may be connected to the support wire lumens 13a to 13c. In this case, for example, the guidewire Wg inserted from the opening of the second connector can be guided to the distal end opening 21 via the guidewire lumen 16.

[0045] In the first modification, the inner diameter of the guidewire lumen 16 is configured to be larger than the inner diameters of the support wire lumens 13a to 13c. The inner diameter of the guidewire lumen 16 and the inner diameter of the center lumen 11 may be the same or different. The inner diameter of the guidewire lumen 16 may be configured to be smaller than the inner diameter of the center lumen 11.

[0046] (Variation 2) 6A is a perspective view showing a schematic view of a part of the tube 102 included in the liquid injection unit 200 of the second modification. In the liquid injection unit 200, the support mechanism 40 includes at least three first support wire lumens 13a to 13c extending in the axial direction X of the tube 102, at least three first support wire ports 14a to 14c opening at different circumferential positions on the outer peripheral surface 102s of the tube 102, at least three second support wire lumens 18a to 18c extending in the axial direction X of the tube 102, and at least three second support wire ports 19a to 19c opening at different circumferential positions on the outer peripheral surface 102s of the tube 102. The first support wire lumens 13a to 13c correspond to the above-mentioned support wire lumens 13a to 13c. The first support wire ports 14a to 14c correspond to the above-mentioned support wire ports 14a to 14c. Each of the second support wire lumens 18a to 18c is a lumen into which at least one support wire Ws can be inserted. The second support wire ports 19a to 19c communicate with each of the second support wire lumens 18a to 18c.

[0047] Fig. 7A is a vertical projection view of the tube 102 in Fig. 6A in the axial direction X. In the example shown in Fig. 7A, in the vertical projection view of the tube 102 in the axial direction X, the second support wire lumens 18a-18c are disposed at positions different from the first support wire lumens 13a-13c in the axial direction X, i.e., positions that do not overlap with the first support wire lumens 13a-13c in the axial direction X. The second support wire lumens 18a-18c are disposed outside the center lumen 11 so as to surround the center lumen 11.

[0048] The inner diameter of the center lumen 11 is configured to be larger than the inner diameters of the second support wire lumens 18a to 18c. The inner diameters of the second support wire lumens 18a to 18c may be the same as or different from the inner diameters of the first support wire lumens 13a to 13c.

[0049] As shown in Fig. 7A, in a vertical projection of the tube 102 in the axial direction X, the puncture catheter ports 12a to 12c and the second support wire ports 19a to 19c are arranged at positions facing each other with respect to the axial direction X of the tube 102. Note that "the puncture catheter ports 12a to 12c and the second support wire ports 19a to 19c are arranged at positions facing each other with respect to the axial direction X of the tube 102" means that the puncture catheter ports 12a to 12c and the second support wire ports 19a to 19c may be arranged at positions substantially facing each other with respect to the axial direction X, and does not necessarily mean that the puncture catheter ports 12a to 12c and the second support wire ports 19a to 19c are arranged at positions directly facing each other with respect to the axial direction X. The opening centers 19d of the second support wire ports 19a to 19c may be located in a range where the angle β defined by the virtual straight line L and the axial direction X satisfies -45°≦β≦45°. 7A, the first support wire ports 14a-14c and the second support wire ports 19a-19c that are closest to each other in the axial direction X may be disposed such that the midpoint Rc of the imaginary line R connecting the opening center 14d of the first support wire ports 14a-14c and the opening center 19d of the second support wire ports 19a-19c faces the puncture catheter ports 12a-12c with respect to the axial direction X of the tube 102. The definition of "facing the axial direction X of the tube 102" is as described above. That is, the midpoint Rc may be disposed in a range where the angle β defined by the imaginary line L and the axial direction X satisfies -45°≦β≦45°.

[0050] Fig. 6B is a diagram showing an example when the puncture catheter Cp and the support wire Ws are inserted into the tube 102 of Fig. 6A. Fig. 7B is a vertical projection of the tube 102 of Fig. 6B in the axial direction X. As shown in Figs. 6B and 7B, in the drug solution injection unit 200 of the second modification, one of the puncture catheter ports 12a-12c from which the puncture catheter Cp is to be delivered and one located opposite to the axial direction X of the tube 10 are selected from the first support wire ports 14a-14c and the second support wire ports 19a-19c, and the support wire Ws is delivered from each of the ports to abut against the inner wall of the blood vessel BV, whereby the drug solution injection unit 200 can be prevented from moving in a direction away from the blood vessel BV due to a repulsive force generated when the puncture needle of the puncture catheter Cp is punctured into a specific internal tissue that is a treatment site.

[0051] Two or more of the at least three second support wire ports 19a-19c may be selected as the second support wire ports 19a-19c from which the support wire Ws is delivered. That is, the support wire Ws may be delivered from each of two or more of the at least three second support wire ports 19a-19c to prevent the liquid injection unit 200 from moving in a direction away from the blood vessel BV. In addition, two or more support wires Ws may be delivered from one of the at least three second support wire ports 19a-19c to prevent the liquid injection unit 200 from moving in a direction away from the blood vessel BV.

[0052] (Variation 3) 8 is a see-through perspective view showing a schematic view of a part of a tube 103 included in a liquid injection unit 300 of Modification 3. The liquid injection unit 300 of Modification 3 has a plurality of puncture catheter sets Sp (Sp1, Sp2) including at least three puncture catheter ports 12a to 12c, and has the same configuration as the liquid injection unit 1 including the tube 10, except that the plurality of puncture catheter sets Sp are arranged at different positions in the longitudinal direction of the tube 103.

[0053] The liquid injection unit 300 includes a plurality of puncture catheter sets Sp (Sp1, Sp2) arranged at different positions in the longitudinal direction of the tube 103. This increases the options for the puncture catheter ports 12a to 12c from which the puncture catheters Cp are delivered, making it easier to inject liquid into a plurality of locations in a specific body tissue that is a treatment site without moving the liquid injection unit 300 back and forth within the blood vessel BV.

[0054] Here, a set including at least three support wire ports 14a-14c is defined as the support set Ss. As shown in Fig. 8, in the liquid injection unit 300 of the third modification, the support set Ss may be disposed between the puncture catheter set Sp1 and the puncture catheter set Sp2 in the axial direction X. With this configuration, the support set Ss can prevent the liquid injection unit 300 from moving in a direction away from the blood vessel BV, both when the puncture wire ports 12a-12c of the distal end puncture catheter set Sp1 are used and when the puncture wire ports 12a-12c of the proximal end puncture wire set Sp2 are used.

[0055] The liquid injection unit 300 may include a plurality of support sets Ss. For example, from the distal end to the proximal end, the puncture catheter set Sp, the support set Ss, the puncture catheter set Sp, the support set Ss, ... may be arranged in this order. When a plurality of support sets Ss are provided, the support wire ports 14a to 14c of the plurality of support sets Ss may each communicate with a common support wire lumen 13a to 13c.

[0056] The embodiment of Modification 2 can also be applied to the liquid injection unit 300 of Modification 3. That is, the liquid injection unit 300 may include a second support set Ss2 including at least three second support wire ports 19a-19c in addition to a first support set Ss1 including at least three first support wire ports 14a-14c. The liquid injection unit 300 may include a plurality of second support sets Ss2.

[0057] (Variation 4) 9 is a schematic diagram showing the structure of a liquid medicine injection unit 400 of Modification 4. In the liquid medicine injection unit 400, the support mechanism 40 includes a balloon member 50 having a balloon 51. That is, the liquid medicine injection unit 400 of Modification 4 has the same configuration as the liquid medicine injection unit 1, except that the puncture catheter ports 12a to 12c and the balloon member 50 are arranged at positions facing each other with respect to the axis X of the tube 10.

[0058] FIG. 10 is a see-through perspective view showing a schematic view of a part of the tube 10 and the balloon member 50 included in the drug solution injection unit 400. FIG. 10 generally corresponds to the part indicated by the symbol A' in FIG. 9. In addition to the balloon 51, the balloon member 50 further includes a long tube 52 and a distal tip 53 attached to the distal end side of the tube 52. The balloon 51 is provided between the distal tip 53 and the tube 52. The balloon member 50 may be integrated with the tube 10 at the proximal end side, or may be separate from the tube 10. When the balloon member 50 is separate from the tube 10, the balloon member 50 may further include a connector (not shown) connected to the proximal end of the tube 52.

[0059] The balloon member 50 can supply fluid to the internal space of the balloon 51 via the tube 52. This causes the balloon 5 to expand.

[0060] 11 is a diagram showing a vertical projection of the tube 10 in FIG. 9 with respect to the axis X direction together with the balloon member 50. As shown in FIG. 11, in the vertical projection of the tube 10 with respect to the axis X direction, the puncture catheter ports 12a to 12c and the balloon member 50 are arranged at positions facing each other with respect to the axis X of the tube 10. Note that "the puncture catheter ports 12a to 12c and the balloon member 50 are arranged at positions facing each other with respect to the axis X of the tube 10" means that the puncture catheter ports 12a to 12c and the balloon member 50 may be arranged at positions substantially facing each other with respect to the axis X, and does not necessarily mean that the puncture catheter ports 12a to 12c and the balloon member 50 are arranged at positions directly facing each other with respect to the axis X as shown in FIG. 11. For example, the center 50a of the balloon member 50 may be located in a range where the angle β defined by the virtual straight line L and the axis X satisfies -45°≦β≦45°.

[0061] In the drug solution injection unit 400, the support mechanism 40 includes a balloon member 50 having a balloon 51, so that the drug solution injection unit 400 can be prevented from moving in a direction away from the blood vessel BV due to the repulsive force generated when the puncture needle is inserted into a specific body tissue that is the treatment site.

[0062] Two or more balloon members 50 may be used as the balloon member 50. That is, two or more balloons 51 may function as the support mechanism 40. In this case, the stability of the drug solution injection unit 400 is further improved. FIG. 11 shows an example in which three balloon members 50 are used as the balloon member 50.

[0063] The above-described center lumen 11, the support wire lumen (first support wire lumen) 13a-13c, the second support wire lumen 18a-18c, and the guidewire lumen 16 are tube bodies formed of resin. The resin material forming the tube bodies of these lumens is not particularly limited, but a resin having good sliding properties with other members is preferable, and examples thereof include fluorine-based resins such as PTFE (polytetrafluoroethylene), PVDF (polyvinylidene fluoride), PFA (perfluoroalkoxyalkane), FEP (perfluoroethylene propene), and ETFE (ethylene tetrafluoroethylene), PE (polyethylene), and PP (polypropylene). The tube bodies forming the center lumen 11, the support wire lumen (first support wire lumen) 13a-13c, the second support wire lumen 18a-18c, and the guidewire lumen 16 may be formed of the same resin material, or may be formed of different resin materials.

[0064] A reinforcing member (not shown) may be disposed on the outer periphery of the tube body. The reinforcing member may be, for example, a braided body (metal braid layer) formed by weaving a plurality of wires into a mesh shape. The reinforcing member may cover the entire outer periphery of the tube body, or may cover a part of the outer periphery of the tube body. Also, a resin outer layer tube (not shown) in which the reinforcing member is embedded may be disposed on the outer periphery of the tube body.

[0065] The tubes 10, 101, 102, and 103 are formed of resin. For example, the tube 10 covers the tube body constituting the center lumen 11 and the tube body constituting the support wire lumen (first support wire lumen) 13a to 13c. The resin material forming the tubes 10, 101, 102, and 103 is not particularly limited, and examples thereof include polyamide, polyamide elastomer, polyester, polyurethane, and polyurethane elastomer. The tubes 10, 101, 102, and 103 may be formed of a single resin material, or may be formed of a plurality of regions using a plurality of resin materials each having different characteristics. In addition, the resin forming the tubes 10, 101, 102, and 103 may contain tungsten powder, and the hardness of the resin may be changed depending on the content of the powder. By incorporating tungsten powder, which is an X-ray opaque powder, into the resin that forms tubes 10, 101, 102, and 103, a technician such as a doctor can accurately determine the position of medical solution injection unit 1 during treatment.

[0066] Although the liquid medicine injection unit according to the present invention has been described above with reference to the drawings, the present invention is not limited to the above-described embodiment, and various modifications are possible. For example, in the above-described embodiment, the liquid medicine injection unit is described as a catheter used to inject a liquid medicine into a specific body tissue that is a treatment site, but the catheter to which the liquid medicine injection unit of the present invention is applied is not limited to applications for liquid medicine injection, and may be applied to, for example, an endoscope, etc. [Explanation of symbols]

[0067] 1,100,200,300,400 Chemical injection unit 10,101,102,103 Tube 11 Center Lumen 12a~12c Puncture Catheter Port 13a to 13c Support wire lumen (first support wire lumen) 14a to 14c Support wire port (first support wire port) 15a~15c Radiopaque markers 16 Guidewire lumen 17 Guidewire port 18a~18c Second support wire lumen 19a-19c Second support wire port 20,201 Tip 21 Tip opening 30 Branch Socket 40 Support mechanism 50 Balloon member 51 Balloon 52 tubes 53 Tip Sp Puncture Catheter Set Ss Support Set Cp puncture catheter Ws Support wire Wg Guidewire

Claims

【Claim 1】 comprising a long tube, the tube has, a central lumen extending in the axial direction of the tube and into which a puncture catheter having a puncture needle at its tip can be inserted, at least three puncture catheter ports that communicate with the central lumen and open at different circumferential positions on the outer peripheral surface of the tube, and a support mechanism that is disposed at positions respectively facing the at least three puncture catheter ports with respect to the axis of the tube and is used to support the tube. The support mechanism includes, at least three support wire lumens that extend in the axial direction of the tube and into each of which at least one support wire can be inserted, and at least three support wire ports that communicate with each of the at least three support wire lumens and open at different circumferential positions on the outer peripheral surface of the tube, a chemical solution injection unit.

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