Treatment system

Abstract

To provide a treatment system of blood and / or coelomic fluid that can easily execute connection check of a pressure measuring part connected to a flow passage whose one end is close to an open end.SOLUTION: A treatment system includes: a filter 11; a pressurizing part having a pump and a valve; a 0th flow passage for connecting a flow passage connection part, a discharge liquid exit of the filter 11, and the valve; a first flow passage for connecting the valve and the flow passage connection part; a second flow passage for connecting the flow passage connection part and a first connection port for first pressure measurement; a third flow passage for connecting the flow passage connection part and a discharge liquid part; a check part for executing connection check of the second flow passage to the first connection port for first pressure measurement; a first pressure measuring part for measuring an in-passage pressure of the second flow passage connected to the first connection port for first pressure measurement; and a control part for controlling the pressurizing part. The pressurizing part is controlled so as to open the valve after pressuring the liquid put in the 0th flow passage in a state that the valve is closed, and the connection check is executed on the basis of the in-passage pressure of the second flow passage pressurized when the valve is opened, measured by the first pressure measuring part.SELECTED DRAWING: Figure 1A

Description

[Technical field]

[0001] The present invention relates to a treatment system for treating blood and / or body cavity fluids. [Background technology]

[0002] Ascites, a type of body cavity fluid, can be treated by removing the fluid from the patient, removing pathogenic substances such as bacteria and cancer cells from it, concentrating it while leaving useful components such as albumin, and then returning the concentrate to the body. This is called cell-free and concentrated ascites reinfusion therapy.

[0003] In such treatments, a body cavity fluid treatment system is generally used (see Patent Document 1). [Prior art documents] [Patent documents]

[0004] [Patent Document 1] JP 2019-13492 A Summary of the Invention [Problem to be solved by the invention]

[0005] In the above-mentioned body cavity fluid processing system and other blood processing systems, the tubes that serve as the flow paths for each liquid, the bags for storing each liquid, the concentrator, and the filter must be replaced every time processing is performed. There are many parts and attachment points that connect to the processing system main body, making the replacement work complicated. In particular, if there is a poor connection of the flow paths to the pressure measurement unit, the processing system main body cannot correctly monitor the pressure inside the tube.

[0006] The present invention has been made in consideration of the above problems, and has an object to provide a processing system capable of checking the connection of a flow path to a pressure measuring unit. [Means for solving the problem]

[0007] That is, the present invention is as follows. [1] 1. A treatment system for treating blood and / or body cavity fluids, comprising: A filter and a pressurizing unit including a pump and a valve; A flow path connection portion; A zeroth flow path connecting the drain outlet of the filter and the valve; A first flow path connecting the valve and the flow path connection portion; a second flow path connecting the flow path connection portion and a first connection port for measuring a first pressure; a third flow path connecting the flow path connection portion and a drainage portion that stores the drainage flowing out from the drainage outlet; a check unit that checks the connection between a first connection port for measuring the first pressure and the second flow path; a first pressure measuring unit that measures a pressure in the second flow path connected to the first connection port for measuring the first pressure; A control unit that controls the pressurizing unit, the control unit controls the pressurizing unit to pressurize the liquid filled in the zeroth flow path with the valve closed and then open the valve; The check unit performs the connection check based on a pressure in the second flow path that is pressurized due to the valve being opened and that is measured by the first pressure measurement unit. Processing system. [2] The first pressure measurement unit measures the pressure in the second flow path based on the timing when the valve changes from a closed state to an open state. The processing system according to [1]. [3] The drainage part of a closed system is connected to the third flow path. The processing system according to [1] or [2]. [4] In the connection check, the checking unit determines that the second flow path is connected to the first connection port for measuring the first pressure when the internal pressure of the second flow path measured by the first pressure measuring unit is equal to or greater than a specified value. The processing system according to any one of [1] to [3]. [5] The check unit performs the connection check based on the internal pressure of the second flow path before and after the pressurization measured by the first pressure measurement unit. The processing system according to any one of [1] to [4]. [6] In the connection check, the checking unit determines that the second flow path is connected to the first connection port for measuring the first pressure when a difference between an internal pressure of the second flow path before and after the pressurization measured by the first pressure measuring unit is equal to or greater than a specified value. The processing system according to any one of [1] to [5]. [7] In the connection check, the checking unit measures the pressure in the second flow path measured by the first pressure measuring unit and / or measures a difference in the pressure in the second flow path before and after the pressurization measured by the first pressure measuring unit a plurality of times, and determines that the second flow path is connected to the first connection port for measuring the first pressure based on the results of the plurality of measurements. The processing system according to any one of [1] to [6]. [8] During the connection check, the checking unit changes the pressurizing pressure applied by the pressurizing unit and checks a plurality of times whether the second flow path is connected to the first connection port for measuring the first pressure, In the connection check, The checking unit determines, based on the multiple confirmation results, that the second flow path is connected to the first connection port for measuring the first pressure. The processing system according to any one of [1] to [7]. [9] At least one of a flow path cross-sectional area, a flow path length, a flow path wall thickness, and a constituent material is different in at least a part of the second flow path and the third flow path. The processing system according to any one of [1] to [8].

[10] A gas is sealed in a portion of the second flow path. The processing system according to any one of [1] to [9].

[11] The pressurizing unit has a second pressure measuring unit that measures the pressurizing pressure. The processing system according to any one of [1] to

[10] .

[12] a concentrator indirectly or directly connected to the filter; a fourth flow path for discharging the effluent removed by the concentrator; a backflow prevention unit provided in the fourth flow path; a branch point provided in the second flow path, The fourth flow path is connected to the branch point. The processing system according to any one of [1] to

[11] .

[13] An output unit that displays a result of the connection check is further provided. The processing system according to any one of [1] to

[12] . Effect of the Invention

[0008] According to the present invention, it is possible to provide a processing system capable of checking the connection of a flow path to a pressure measuring unit. [Brief description of the drawings]

[0009] [Figure 1A] FIG. 1 is a schematic diagram illustrating one aspect of a processing system according to an embodiment of the present invention. [Figure 1B] FIG. 2 is a diagram illustrating an example of a hardware configuration of the information processing apparatus according to the present embodiment. [Figure 1C] FIG. 2 is a diagram illustrating an example of a functional block configuration of the information processing apparatus according to the present embodiment. [Figure 1D]FIG. 11 is a schematic diagram illustrating another aspect of the processing system of the present embodiment. [Figure 2A] FIG. 11 is a schematic diagram showing a change in pressure in the 0th flow path. [Figure 2B] FIG. 6 is a schematic diagram showing a change in pressure in a second flow path. [Figure 3A] 13 shows an example of a flowchart for checking a connection. [Figure 3B] 13 shows another example of a flowchart for checking a connection. [Figure 4A] FIG. 2 is a front view showing one embodiment of a processing bag. [Figure 4B] FIG. 2 is a front view showing one embodiment of a treated bag. [Figure 4C] FIG. 2 is a front view showing one embodiment of a drainage section. [Figure 4D] 1 shows a schematic diagram of one embodiment of an ascites collection line. [Figure 4E] A schematic diagram of one embodiment of flow channel 14 is shown. [Figure 4F] FIG. 2 is a diagram showing an embodiment of a flow channel 45. [Figure 4G] 1B is a diagram showing an example of the configuration of a downstream portion from the 0th flow path in FIG. 1A. FIG. [Figure 4H] FIG. 2 is a diagram showing an example of the configuration of a downstream portion from the 0th flow path in FIG. 1D. [Figure 4I] 1B is a diagram showing a configuration example of a portion downstream from a fourth flow path in FIG. 1A. FIG. [Figure 4J] 1E is a diagram showing a configuration example of a portion downstream from a fourth flow path in FIG. 1D. FIG. [Figure 4K] A partial enlarged view of the flow circuit of the processing system. [Figure 4L] A partial enlarged view of the flow circuit of the processing system. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0010] Hereinafter, an embodiment of the present invention (hereinafter referred to as "the present embodiment") will be described in detail with reference to the drawings as necessary, but the present invention is not limited to this, and various modifications are possible without departing from the gist of the present invention. In the drawings, the same elements are given the same reference numerals, and duplicated explanations will be omitted. Furthermore, positional relationships such as up, down, left, and right are based on the positional relationships shown in the drawings, unless otherwise specified. Furthermore, the dimensional ratios of the drawings are not limited to those shown in the drawings.

[0011] 1. Processing System FIG. 1A is a schematic diagram showing one aspect of the processing system of this embodiment. The processing system 1 of this embodiment is a processing system for processing blood and / or body cavity fluid, and includes a filter 11, a pressurizing unit 90, a second connection port 83 to which a drainage unit 82 is connected, a first connection port 84a for measuring a first pressure, a flow path connection unit 19e, a 0th flow path 19a connecting the drainage outlet of the filter 11 and a valve, a first flow path 19b connecting the valve 81 and the flow path connection unit 19e, a second flow path 19c connecting the flow path connection unit 19e and the first connection port 84a for measuring the first pressure, a third flow path 19d connecting the flow path connection unit 19e and the drainage unit 82 and having a second connection port 83, a check unit 85 that checks the connection between the first connection port 84a for measuring the first pressure and the second flow path 19c, a first pressure measuring unit 87 that measures the internal pressure of the second flow path connected to the first connection port 84a for measuring the first pressure, and a control unit 86 that controls the pressurizing unit 90.

[0012] The control unit 86 of the processing system 1 controls the pressurizing unit 90 to increase the pressure on the liquid filled in the 0th flow path 19a with the valve 81 closed and then open the valve 81, the first pressure measuring unit 87 measures the internal pressure of the second flow path 19c via the first connection port 84a, and the checking unit 85 may perform a connection check based on the internal pressure of the second flow path 19c that has been pressurized due to the opening of the valve 81.

[0013] A processing system for processing blood and / or body cavity fluid is used by a user such as a medical professional who replaces all of the flow paths, etc., each time the system is used. Therefore, checking whether the flow path is connected to the pressure measurement unit has been left to the medical professional, etc. In contrast, according to this embodiment, the processing system can reliably check the connection of the flow path to the pressure measurement unit without leaving it to the medical professional, etc. Furthermore, the processing system can reliably check the connection of the flow path to the pressure measurement unit in a relatively short time.

[0014] In addition, a state in which a part of the flow path is connected to a drainage bag or the like is a state that is pseudo-close to an open end. In such a case, if liquid is flowed into a drainage bag or the like and a connection check is performed based on the resulting increase in the pressure inside the path, it takes time for the pressure to increase, so there is a concern that the connection check cannot be performed promptly. In contrast, according to this embodiment, the processing system can reliably perform a connection check of the flow path to the pressure measurement unit.

[0015] 1A, the processing system 1 of this embodiment will be described in detail. First, the processing system 1 may include a processing bag 10 as a storage unit for unprocessed blood and / or body cavity fluid, a filter 11, a concentrator 12, a processed bag 13 as a collection unit for blood and / or body cavity fluid after filtering and concentrating, and an information processing device 100. The information processing device 100 may include various functional units, such as a check unit 85, a control unit 86, a first pressure measurement unit 87, and a second pressure measurement unit 88.

[0016] The configuration of the processing system 1 will be described below using ascites as an example of body cavity fluid, but the processing target of the processing system 1 of this embodiment is not limited to ascites, and the processing system 1 can also be applied to other body cavity fluids and blood.

[0017] The processing bag 10 is, for example, a soft bag, and can contain ascites collected from a patient. During the connection check, the processing bag 10 may contain a liquid such as saline or water, or a gas such as air.

[0018] FIG. 4A shows a front view of the processing bag 10. The processing bag 10 is not particularly limited, and may be, for example, a bag made of soft polyvinyl chloride and having a substantially rectangular shape when laid flat. The capacity may be about 3 L, and the size may be about 350 mm in length and about 250 mm in width. The processing bag 10 may have a capacity memory (not shown) for indicating the volume of the content liquid, and a user identification mark (not shown) for indicating the patient from whom the ascites to be filled in the processing bag 10 was collected. The capacity memory and the user identification mark can be attached to the bag body, printed directly on the bag body, or formed on the bag body by other methods.

[0019] A seal portion of a certain width is provided on each of the four sides of the processing bag 10. The seal portion may be provided with a hook hole 10a. A plurality of hook holes 10a may be provided, for example, at the center of the upper side or at the corners of the lower side of the seal portion.

[0020] A mesh portion 10b may be provided inside the processing bag 10. When the ascites is sent from the processing bag 10 to the filter 11 through the pipeline 10c, the mesh portion 10b can inhibit the coagulation of the ascites or inhibit the coagulated ascites from flowing to the filter 11. This can also prevent the flow path 14 and the like from being blocked.

[0021] The pipeline 10c may be located at the lower side of the seal portion, and may extend to the outside and inside of the processing bag 10, respectively, and may communicate with the outside and inside of the processing bag 10. In the part of the pipeline 10c that extends to the inside of the processing bag 10, an opening by a notch 10e may be provided in addition to the opening at the end 10d. The ascites in the processing bag 10 may flow from the notch 10e and the end 10d through the pipeline 10c to the filter 11. The notch 10e allows the ascites to flow out stably. Therefore, the openings of the notch 10e and the end 10d can be designed to be smaller, thereby suppressing the outflow of the coagulated ascites to the filter 11. In addition, a connector 10f that connects to the flow path 14 during ascites filtration and concentration may be located in the part of the pipeline 10c that extends to the outside.

[0022] In FIG. 4A, the mesh portion 10b is omitted in order to depict the end portion 10d and the notch 10e, but this does not mean that there is no mesh portion 10b around the end portion 10d and the notch 10e of the pipeline 10c.

[0023] Furthermore, the processing bag 10 may have a pipeline 10g that communicates the outside and inside of the processing bag 10. The pipeline 10g may be located at the lower side of the sealed portion. A connector 10h that connects to an ascites collection line when collecting ascites may be located in the part of the pipeline 10g that extends outward. Note that it is preferable that one of the connectors 10f and 10h is male and the other is female to prevent a mistake in connection.

[0024] FIG. 4D shows one embodiment of an ascites collection line 10i. As shown in FIG. 4D, the ascites collection line 10i has a connector 10j connected to a puncture needle or the like for collecting ascites from a patient, and a connector 10k connected to a pipeline 10g. The ascites collection line 10i may also include a regulator 10l (roller clamp) for adjusting the flow rate and a chamber 10m for visually checking the flow rate (velocity of droplets). The connectors 10j and 10k may be capped before connection.

[0025] The processing bag 10 may also have a port 10n for collecting a portion of the original ascites fluid or for injecting a drug or the like.

[0026] The filter 11 has, for example, a cylindrical housing. The filter 11 has liquid passages 11a and 11b at both ends in the longitudinal direction (vertical direction) and two liquid passages 11c and 11d on the side. The filter 11 may remove a predetermined pathogenic substance such as bacteria or cancer cells and allow a predetermined useful component such as albumin to pass through. During a connection check, liquids such as saline or water or gases such as air may pass through each space in the filter 11. In this specification, the up and down of the processing system 1 are based on the posture during normal use.

[0027] The filter 11 is equipped with a filtration membrane 30 that removes predetermined pathogenic substances such as bacteria and cancer cells and allows predetermined useful components such as albumin to pass through. The filtration membrane 30 is composed of, for example, a number of hollow fiber membranes. A space 30a on the primary side of the filtration membrane 30 (the internal space of the hollow fiber membrane) communicates with the liquid passage ports 11a and 11b, and a space 30b on the secondary side of the filtration membrane 30 (the external space of the hollow fiber membrane) communicates with the liquid passage ports 11c and 11d.

[0028] A flow path 45 is connected to the liquid passage port 11c of the filter 11. The flow path 45 is connected to the connection port 46. A second pressure measuring unit 88 may be connected to the connection port 46. The second pressure measuring unit 88 may be a pressure measuring device such as a pressure sensor. That is, the flow path 45 may be connected to the pressure sensor via the connection port 46. The connection port 46 may be an air opening portion that can introduce gas into the filter 11 through the flow path 45. The connection of the flow path 45 may be checked by closing the valves 41 and 81 and pressurizing the filter 11 with the pump 51 while the valve 50 is open. The connection port 46 may be configured to be switchable between the second pressure measuring unit 88 and the air opening portion. The connector of the flow path 45 connected to the liquid passage port 11c may be capped before being connected to the air vent 11c.

[0029] 4F shows one embodiment of the flow path 45. Both ends of the flow path 45 may be marked with a color or other mark 45a. This allows the user to easily confirm the connection destination (for example, the liquid passage port 11c or the second pressure measurement unit 88) based on the mark 45a. The flow path 45 may also have a drip chamber 45b.

[0030] The concentrator 12 has, for example, a cylindrical housing. The concentrator 12 has liquid passages 12a and 12b at both ends in the longitudinal direction (vertical direction) and two liquid passages 12c and 12d on the side. The concentrator 12 may, for example, remove water from ascites to concentrate it. During the connection check, liquids such as saline or water or gases such as air may pass through each space in the concentrator 12.

[0031] The concentrator 12 is equipped with a concentration membrane 40 that removes water from, for example, ascites and concentrates the fluid. The concentration membrane 40 is composed of, for example, a number of hollow fiber membranes. A space 40a on the primary side of the concentration membrane 40 (the inner space of the hollow fiber membrane) communicates with the liquid passage ports 12a and 12b, and a space 40b on the secondary side of the concentration membrane 40 (the outer space of the hollow fiber membrane) communicates with the liquid passage ports 12c and 12d.

[0032] The treated bag 13 is, for example, a soft bag, and can contain concentrated ascites concentrated by the concentrator 12. The treated bag 13 may be placed at a lower position than the processing bag 10. During the connection check, the treated bag 13 may contain a liquid such as saline or water, or a gas such as air, that has passed through the concentrator 12.

[0033] FIG. 4B shows a front view of treated bag 13. Treated bag 13 is not particularly limited, and may be, for example, a substantially rectangular bag laid flat made of soft polyvinyl chloride. The volume may be about 1 L, and the size may be about 290 mm in length and about 150 mm in width. Treated bag 13 may have a volume memory (not shown) for indicating the volume of the liquid contained therein, and a user identification mark (not shown) for indicating the patient from whom ascites was collected in treated bag 13. The volume memory and user identification mark may be attached to the bag body, printed directly on the bag body, or formed on the bag body by other methods.

[0034] A seal portion of a fixed width is provided on each of the four sides of the processed bag 13. The seal portion may be provided with a hook hole 13a. A plurality of hook holes 13a may be provided, for example, at the center of the upper side or at the corners of the lower side of the seal portion.

[0035] The treated bag 13 may have a pipeline 13b and a pipeline 13c at the lower side of the seal portion. The pipeline 13b and the pipeline 13c may communicate with the outside and the inside of the treatment bag 10, respectively. Connectors 13d and 13e may be located in the portions of the pipeline 13b and the pipeline 13c that extend outward, respectively. The pipeline 13b is connected to the flow path 16 via the connector 13d. The pipeline 13c is connected to the flow path 18 via the connector 13e. Note that it is preferable that one of the connectors 13d and the connector 13e is a male type and the other is a female type so as to avoid mistakes in connection.

[0036] The treated bag 13 may also have a port 13f for collecting a portion of the concentrated ascites or for injecting medicine or the like, and a port 13g for connecting to a puncture needle when reinjecting the ascites.

[0037] The flow path 14 connects the processing bag 10 and the filter 11. The upstream end of the flow path 14 is connected to the processing bag 10, and the downstream end of the flow path 14 is connected to the liquid passage 11a of the filter 11. During a connection check, a liquid such as physiological saline or water or a gas such as air may flow from the processing bag 10 to the liquid passage 11a of the filter 11 through the flow path 14. During processing, ascites may flow from the processing bag 10 to the liquid passage 11a of the filter 11 through the flow path 14. The flow path 14 may be provided with a valve 41 for opening and closing the flow path 14. In this specification, the term "upstream side" refers to the upstream side during normal ascites processing in which the ascites flows through the filter 11 and the concentrator 12 in this order, and the term "downstream side" refers to the downstream side during normal ascites processing.

[0038] FIG. 4E shows a schematic diagram of the flow path 14. The flow path 14 may have a connector 14a that connects to the processing bag 10 and a connector 14b that connects to the filter 11. The flow path 14 may have a detachable plastic needle 14c at the tip of the connector 14a before being connected to the processing bag 10. The flow path 14 can be applied to both a physiological saline bag that is connected with the plastic needle 14c and a physiological saline bag that is connected with the connector 14g. The plastic needle 14c may be capped with a cap 14d before being connected. The connector 14b may also be capped before being connected.

[0039] For example, the plastic needle 14c may be used to pierce the rubber plug of a saline bag for priming. At this time, the plastic needle 14c can be connected to the saline bag during priming, and the flow path is filled with saline for washing. After priming, the plastic needle 14c is removed from the connector 14a, and the connector 14a is connected to the pipeline 10c of the processing bag 10.

[0040] In this embodiment, "priming" refers to an operation of filling at least a part of the flow path of the treatment system with physiological saline before ascites filtration and concentration, and passing the physiological saline through at least a part of the flow path of the treatment system by driving a pump or utilizing the weight of the physiological saline. A "physiological saline bag" is a bag filled with physiological saline used for priming.

[0041] The flow path 14 may have a mark 14e for clearly indicating the connection point to the on-off valve (valve 41). This makes it easier to install the on-off valve (valve 41) at an appropriate position (between the two marks 14e) of the flow path 14. In addition, a mark 14f of color or the like may be attached to the end side of the flow path 14. This allows the user to easily confirm the connection destination (for example, the processing bag 10 or the filter 11) based on the mark 14f.

[0042] The 0th flow path 19a connects the filter 11 and the valve 81. An upstream end of the 0th flow path 19a is connected to the drain outlet 11b of the filter 11. A downstream end of the 0th flow path 19a is connected to the valve 81. During a connection check, a liquid such as physiological saline or water or a gas such as air may flow from the drain outlet 11b of the filter 11 to the valve 81 through the 0th flow path 19a. Furthermore, the liquid or gas supplied to the valve 81 may be pressurized by a pump or the like capable of pressurizing the liquid or gas filled in the 0th flow path 19a. During processing, the filtered ascites to be discarded may flow from the drain outlet 11b of the filter 11 to the valve 81 through the 0th flow path 19a. The filtered ascites may contain a predetermined pathogenic substance such as bacteria or cancer cells.

[0043] The first flow path 19b connects the valve 81 and the flow path connection part 19e. An upstream end of the first flow path 19b is connected to the valve 81. In addition, a downstream end of the first flow path 19b is connected to the flow path connection part 19e. During a connection check, liquid such as saline or water or gas such as air flows into the first flow path 19b when the valve 81 is opened. In addition, during membrane cleaning of the filter 11, the saline used for membrane cleaning flows from the valve 81 into the first flow path 19b.

[0044] There are no particular limitations on the 0th flow path 19a and the 1st flow path 19b as long as they are located upstream and downstream of the valve 81, and they may be the same tube or different tubes.

[0045] FIG. 4G shows a configuration example of the downstream portion from the 0th flow path 19a in the embodiment shown in FIG. 1A. The 0th flow path 19a may have a connector 19aa connected to the filter 11. The 0th flow path 19a may have a mark 19ab for clearly indicating a connection point to an on-off valve (valve 81). This makes it easier to install the on-off valve (valve 81) at an appropriate position (between the two marks 19ab) of the 0th flow path 19a. In addition, a mark 19ac of color or the like may be attached to the end side of the 0th flow path 19a. This allows the user to easily confirm the connection destination (for example, the filter 11) based on the mark 19ac. The connector 19aa may be capped before connection.

[0046] As shown in Fig. 4G, the 0th flow path 19a may have a branch flow path 19ad and a branch flow path 19ae between the valve 81 and the flow path connection part 19e. The branch flow path 19ad may have a connector 19af at an end. The branch flow path 19ae may also have a connector 19ag at an end. As shown in Fig. 4G, it is preferable that one of the connectors 19af and 19ag is male and the other is female, and that they are connected to each other during ascites filtration and concentration.

[0047] During priming or connection check, connectors 19af and 19ag may not be connected to each other, and one of connectors 19af, 19ag may be connected directly or indirectly to one of connectors 13d, 13e, and the other of connectors 19af, 19ag may be connected directly or indirectly to the other of connectors 13d, 13e.

[0048] As shown in Fig. 4G, the second flow path 19c may be provided with a drip chamber 19ca. One end of the second flow path 19c may be connected to a pressure measuring device via a first connection port 84a to measure the internal pressure of the second flow path 19c. The third flow path 19d may have a connector 19da that connects to a drainage section 82 that stores the drainage flowing out from the drainage outlet 11b. The connector 19da corresponds to an example of a connection port 83.

[0049] Here, the valve 81 and the pump 51 located in the flow path 15 may constitute a pressurizing unit 90. Specifically, when the pump 51 sends liquid in the direction F1, the liquid is supplied from the liquid passage port 11d of the filter 11 to the secondary side space 30b, and the liquid is supplied to the primary side space 30a via the filtration membrane 30, and the liquid flows into the 0th flow path 19a from the liquid passage port 11b.

[0050] If the valve 81 is closed when the pump 51 sends liquid in the direction F1, the pressure applied to the liquid filling the 0th flow path 19a increases. That is, the pump 51 pressurizes the liquid filling the 0th flow path 19a. Then, after the pressure applied to the liquid filling the 0th flow path 19a is increased, the valve 81 is opened, so that the liquid supplied to the 0th flow path 19a flows into the first flow path 19b. In this manner, the valve 81 and the pump 51 may constitute a pressurizing unit 90 for the first flow path 19b.

[0051] In the above, an embodiment in which the valve 81 and the pump 51 constitute the pressurizing unit 90 has been described, but the embodiment of the pressurizing unit 90 is not limited to this. The pump that constitutes the pressurizing unit 90 is not limited to the pump 51, and may be any pump that is capable of pressurizing the liquid or gas filled in the 0th flow path 19a. For example, the pump that constitutes the pressurizing unit 90 is not limited to the pump 51 installed in the flow path 15, and may be a pump (not shown) provided in the 0th flow path 19a.

[0052] The operation of the pressurizing unit 90, that is, the opening and closing control of the valve 81 and the drive control of the pump 51 or other pumps, may be executed by the control unit 86. The control unit 86 can also control the pressurizing pressure by the pressurizing unit 90. The control unit 86 may open the valve 81 when the pressure applied to the liquid filled in the 0th flow path 19a exceeds a threshold value.

[0053] The processing system 1 may also include a pressure measurement unit that measures the pressurized pressure. The pressurized pressure measurement unit measures the pressure applied to the liquid filled in the 0th flow path 19a. As an example of the pressure measurement unit, the processing system 1 may include a second pressure measurement unit 88 that measures the pressurized pressure. The second pressure measurement unit 88 measures the pressure applied to the liquid filled in the 0th flow path 19a.

[0054] The second flow path 19c connects the flow path connection part 19e and the first connection port 84a for measuring the first pressure. One end of the second flow path 19c is connected to the flow path connection part 19e. The other end (connection port 84b) of the second flow path 19c is connected to the first connection port 84a for measuring the first pressure. The second pressure measurement part 88 may be connected to the connection port 46. The second pressure measurement part 88 is a pressure measurement device such as a pressure sensor. That is, the flow path 45 may be connected to the pressure sensor via the connection port 46. The first connection port 84a for measuring the first pressure may be connected to a first pressure measurement device such as a pressure sensor and closed. In other words, the second flow path 19c may not be one through which liquid or gas passes, but may be one that transmits the inflow pressure of the liquid or gas from the flow path connection part 19e to the first connection port 84a.

[0055] During a connection check, the second flow path 19c may transmit to the first connection port 84a the pressure of a liquid such as physiological saline or water or a gas such as air flowing in at a predetermined pressure from the flow path connection portion 19e toward the first connection port 84a. Similarly, during processing, the second flow path 19c may transmit the inflow pressure from the flow path connection portion 19e to the first connection port 84a.

[0056] A gas may be sealed in a portion of the second flow path 19c, or a drip chamber 19ca may be provided, which can prevent the first pressure measuring device from coming into contact with liquid.

[0057] The third flow path 19d connects the flow path connection part 19e with a second connection port 83 connected to the drainage part 82. An upstream end of the third flow path 19d is connected to the flow path connection part 19e. In addition, a downstream end of the third flow path 19d has a second connection port 83 connected to the drainage part 82. During a connection check or during processing, the second connection port 83 may be connected to the drainage part 82 that accommodates, for example, liquid or gas discharged from the filter 11.

[0058] The drainage part 82 may be a closed system or an open system. From the viewpoint of preventing the drainage from contaminating other places, it is preferable that a closed drainage part 82 is connected to the second connection port 83. The drainage part 82 may be, for example, a soft bag, and can contain the ascites filtered by the filter 11. During the connection check, the drainage part 82 may contain a liquid such as saline or water, or a gas such as air, that has passed through the filter 11.

[0059] 4C shows a front view of the drainage section 82. The drainage section 82 is not particularly limited, and may be, for example, a generally rectangular bag made of soft polyvinyl chloride when laid flat. The capacity may be about 5 L, and the size may be about 390 mm in length and about 280 mm in width. The drainage section 82 may have a capacity mark (not shown) for indicating the volume of the liquid contained therein, and a user identification mark (not shown) for indicating the patient from whom the ascites to be filled in the drainage section 82 was collected. The capacity mark and the user identification mark may be attached to the bag body, printed directly on the bag body, or formed on the bag body by other methods.

[0060] A seal portion of a fixed width is provided on each of the four sides of the drainage portion 82. A hook hole 82a may be provided in the seal portion. A plurality of hook holes 82a may be provided, for example, one or more may be provided on the upper side of the seal portion, and one or more may be provided on the corners of the lower side.

[0061] The drainage section 82 may have a pipeline 82b located on the upper side of the sealed section and a pipeline 82c located on the lower side of the sealed section. The pipelines 82b and 82c may each communicate with the outside and inside of the drainage section 82. A connector 82d that connects to the third flow path 19d may be located in a portion of the pipeline 82b that extends outward. Also, a cock 82e may be located in a portion of the pipeline 82c that extends outward.

[0062] Moreover, a drainage section 91, which will be described later, may be configured similarly to the drainage section 82.

[0063] The check unit 85, the control unit 86, the first pressure measuring unit 87, and the second pressure measuring unit 88 may be functional units included in an information processing device 100 included in the processing system 1. The information processing device 100 is not particularly limited, but examples thereof include computers such as tablets and personal computers.

[0064] 1B is a diagram showing an example of a hardware configuration of the information processing device 100. The information processing device 100 includes a processor 111 such as a CPU (Central Processing Unit) or a GPU (Graphical Processing Unit), a storage device 112 such as a memory, an HDD (Hard Disk Drive) and / or an SSD (Solid State Drive), a communication IF (Interface) 113 for performing wired or wireless communication, an input device 114 for accepting an input operation, and an output device 115 for outputting information. The input device 114 is, for example, a keyboard, a touch panel, a mouse, and / or a microphone. The output device 115 is, for example, a display, a touch panel, and / or a speaker.

[0065] FIG. 1C is a diagram showing an example of a functional block configuration of the information processing device 100. The information processing device 100 may include a check unit 85, a control unit 86, a first pressure measurement unit 87, a second pressure measurement unit 88, and an output unit 89. The storage unit 130 can be realized by using a storage device 112 included in the information processing device 100. The check unit 85, the control unit 86, and the output unit 89 can be realized by the processor 111 of the information processing device 100 executing a program stored in the storage device 112. The program can be stored in a storage medium. The storage medium storing the program may be a non-transitory computer readable storage medium. The non-transitory storage medium is not particularly limited, and may be, for example, a storage medium such as a USB memory or a CD-ROM.

[0066] In this embodiment, the check unit 85, the first pressure measurement unit 87, and the control unit 86 may cooperate to perform the connection check. In addition, during the check, the second pressure measurement unit 88 that measures the pressurized pressure by the pressurizing unit 90 may also cooperate. Specifically, the control unit 86 of the processing system 1 controls the pressurizing unit 90 to pressurize the 0th flow path 19a by the pump 51 or the like with the valve 81 closed, and then to open the valve 81, the first pressure measurement unit 87 measures the channel pressure of the second flow path 19c, and the check unit 85 performs the connection check based on the channel pressure of the second flow path 19c that is pressurized by opening the valve 81. In addition, at this time, the second pressure measurement unit 88 may measure the channel pressure of the 0th flow path 19a pressurized by the pressurizing unit 90, and transmit information on the in-furnace pressure of the 0th flow path 19a to the control unit 86 and / or the check unit 85.

[0067] The check unit 85 checks the connection of the second flow path 19c to the first connection port 84a for measuring the first pressure. In the connection check, the check unit 85 may determine that the second flow path 19c is connected to the first connection port 84a for measuring the first pressure when the pressure in the second flow path 19c measured by the first pressure measurement unit 87 is equal to or greater than a specified value. When the pressure in the path is equal to or greater than the specified value, it can be said that there is no connection failure and the pressure is transmitted to the second flow path 19c. On the other hand, for example, when the pressure in the second flow path 19c measured by the first pressure measurement unit 87 is less than a specified value, it may be considered that there is a connection failure somewhere in the flow path. The check unit 85 may check whether the flow path 45 is connected to the connection port 46. Specifically, the check unit 85 checks whether the flow path 45 is connected to the connection port 46 based on the pressure measured when the pump 51 is driven to pressurize the flow path 45 with the valves 41 and 81 closed and the valve 50 open. The method of checking the connection of the flow path 45 is different from the method of checking the connection of the flow path 19c, which will be described later. That is, the checking unit 85 performs the connection check using a connection check method that corresponds to the connection port.

[0068] In addition, in the connection check, the check unit 85 may perform the connection check based on the line pressure of the second flow path 19c before and after pressurization measured by the first pressure measurement unit 87. In this case, if the difference between the line pressure before and after pressurization is equal to or greater than a specified value, it may be determined that the second flow path 19c is connected to the first connection port 84a for measuring the first pressure. Here, the line pressure before and after pressurization can also be referred to as the line pressure before and after the opening of the valve 81 of the pressurization unit 90. If there is a change in the line pressure before and after pressurization, it can be said that the pressure caused by the opening of the valve 81 is transmitted to the second flow path 19c. Then, if the amount of change, that is, the difference between the line pressure before and after pressurization, is equal to or greater than a specified value, it can be said that there is no connection failure and that the pressure is transmitted to the first pressure measurement unit 87 via the second flow path 19c. On the other hand, for example, if the difference between the line pressure before and after pressurization is less than a specified value, it may be considered that there is a connection failure somewhere in the flow path.

[0069] The control unit 86 controls the pressurizing unit 90. The control unit 86 also controls the operation of each device, such as the pump 51, the pump 60, the valve 50, and the valve 70, and can execute a connection check process and a process of blood and / or body cavity fluid. The control unit 86 can realize each process by, for example, executing a program stored in the memory with the CPU.

[0070] 2A shows one mode of change in the pressure in the 0th flow path 19a when the control unit 86 pressurizes the 0th flow path 19a with the pump 51 or the like while the valve 81 is closed, and then controls the pressurizing unit 90 to open the valve 81. As shown in FIG. 2A, when the valve 81 is opened after the valve 81 is closed and the 0th flow path 19a is pressurized, the pressure in the 0th flow path 19a decreases over time from when the valve 81 is opened. The pressure in the 0th flow path 19a may be measured by the second pressure measuring unit 88.

[0071] 2B shows one mode of change in the pressure in the second flow path 19c when the control unit 86 increases the pressure on the liquid filled in the 0th flow path 19a by the pump 51 or the like with the valve 81 closed, and controls the pressurizing unit 90 to open the valve 81 when the pressure on the liquid filled in the 0th flow path 19a exceeds a threshold value. As shown in FIG. 2B, when the valve 81 is opened after closing the valve 81 to increase the pressure on the liquid filled in the 0th flow path 19a, the pressure in the second flow path 19c temporarily increases over time from when the valve 81 is opened, but then decreases as the pressure from the 0th flow path 19a decreases. Note that the pressure in the second flow path 19c is measured by the first pressure measuring unit 87, but this is not limited thereto, and it may be measured by another method.

[0072] As shown in FIG. 2A and FIG. 2B, by increasing the pressure applied to the liquid filled in the 0th flow path 19a and then opening it, a sufficient change can be caused in the pressure inside the second flow path 19c. When the check unit 85 detects such a change, it may determine that the second flow path 19c is normally connected to the first connection port 84a, and when the first pressure measurement unit 87 cannot detect the pressure change even though the pressurized 0th flow path 19a is opened, it may determine that the second flow path 19c is not connected to the first connection port 84a or that there is a problem with the connection. With such a processing system, it is possible to reliably check that the second flow path 19c is connected to the first connection port 84a by detecting the change in the pressure inside the second flow path 19c. More specifically, since the first flow path 19b branches into the second flow path 19c and the third flow path 19d, the second flow path 19c is less likely to be pressurized than when there is no branch. However, since the pressure applied to the liquid filled in the 0th flow path 19a is high while the valve 81 is closed as described above, the pressure transmitted to the second flow path 19c also increases the moment the valve 81 is opened. Therefore, it is possible to reliably check the connection of the second flow path 19c to the first connection port 84a.

[0073] The first pressure measuring unit 87 measures the pressure in the second flow path 19c connected to the first connection port 84a for measuring the first pressure. At this time, the first pressure measuring unit 87 may measure the pressure in the second flow path 19c based on the timing when the valve changes from a closed state to an open state. For example, the first pressure measuring unit 87 may measure the pressure in the second flow path 19c within a predetermined time from the timing when the valve 81 changes to an open state. In addition, the first pressure measuring unit 87 may perform measurements over time as shown in FIG. 2A and FIG. 2B, and the check unit 85 may check the connection of the second flow path 19c to the first connection port 84a for measuring the first pressure from the pressure difference between the opening timing and the timing after a predetermined time has elapsed based on this opening timing. The first pressure measuring unit 87 is, for example, connected to a drip chamber (not shown) and can measure the pressure in the second flow path 19c. The measurement result of the first pressure measuring unit 87 may be output to, for example, the check unit 85 or the control unit 86.

[0074] The second pressure measuring unit 88 may measure the pressure applied to the liquid filled in the 0th flow path 19a that has been pressurized by the control unit 86 controlling the pressurizing unit 90. The second pressure measuring unit 88 is connected to, for example, the flow path 45, and can measure the pressure applied to the liquid filled in the 0th flow path 19a. The measurement result of the second pressure measuring unit 88 may be output to, for example, the check unit 85 or the control unit 86.

[0075] The output unit 89 may display the result of the connection check. If the output device 115 has a display, the output unit 89 may control the display of the result of the connection check. If the output device 115 has a speaker, the output unit 89 may output the result of the connection check, for example, an alert of a poor connection, by voice.

[0076] The memory unit 130 may have various data used for connection checks, and may record, for example, data measured by the first pressure measuring unit 87 and the second pressure measuring unit 88, various specified values ​​for determining that a connection is established, and the like.

[0077] The flow path 15 connects the filter 11 and the concentrator 12. The upstream end of the flow path 15 is connected to the liquid passage 11d of the filter 11, and the downstream end of the flow path 15 is connected to the liquid passage 12a at the upper end of the concentrator 12. That is, the liquid passage 11d of the filter 11 is the outlet of the filter 11, and the liquid passage 12a of the concentrator 12 is the inlet of the concentrator 12. During the connection check, physiological saline may flow from the physiological saline bag 24 toward the filter 11 side through the flow path 15 in the direction F1. During the treatment, filtered ascites may flow from the filter 11 side toward the concentrator 12 side through the flow path 15. The filtered ascites may contain a predetermined useful component such as albumin.

[0078] In the flow path 15, for example, a valve 50, a pump 51, a drip chamber 52, and an introduction part 53 may be provided in this order from the upstream side to the downstream side. In addition, a valve 25d may be provided in the flow path 15 between the drip chamber 52 and the concentrator 12. The valves 50 and 25d are configured to be able to open and close the flow path 15.

[0079] The pump 51 may constitute a pump in the pressurizing unit 90. The pump 51 is not particularly limited, and may be, for example, a tube pump that pumps liquid or gas in predetermined directions F1 and F2 by manipulating a tube of the flow path 15, and may have a function as a blocking means for blocking the tube when the pump is stopped.

[0080] The introduction portion 53 may be a portion that introduces a gas such as air into the flow path 15 during a connection check.

[0081] The flow path 16 connects the concentrator 12 and the treated bag 13. The upstream end of the flow path 16 is connected to the liquid passage 12b at the lower end of the concentrator 12, and the downstream end of the flow path 16 is connected to the treated bag 13. In other words, the liquid passage 12b of the concentrator 12 serves as a first outlet of the concentrator 12.

[0082] A pump 60 may be provided in the flow path 16. The pump 60 may be a tube pump that pumps liquid through a tube in the flow path 16. The pump 60 may also function as a blocking means for blocking the tube when the pump is stopped.

[0083] An upstream end of the fourth flow path 17 is connected to, for example, the liquid passage ports 12c and 12d of the concentrator 12. That is, the liquid passage ports 12c and 12d of the concentrator 12 serve as second outlets of the concentrator 12. The upstream end of the fourth flow path 17 may be connected to only one of the liquid passage ports 12c and 12d. A downstream end of the fourth flow path 17 may be connected to a drainage section 91 that accommodates the drainage liquid removed from the ascites by the concentrator 12.

[0084] 4I shows an example of the configuration of the fourth flow path 17 in the embodiment shown in FIG. 1A. The fourth flow path 17 may have connectors 17a and 17b connected to the liquid passage ports 12c and 12d of the concentrator 12. The fourth flow path 17 may also be provided with a backflow prevention unit 65. The backflow prevention unit 65 can prevent the liquid discharged from the concentrator 12 from flowing back through the fourth flow path 17. Furthermore, the fourth flow path 17 may have a connector 17c connected to the drainage unit 91. The connectors 17a, 17b, and 17c may be capped before being connected.

[0085] Further, a mark 17d such as a color may be provided on the end side of the fourth flow path 17. This allows the user to easily confirm the connection destination (for example, the concentrator 12 or the drainage part 91) based on the mark 17d.

[0086] The drainage part 91 may be a closed system or an open system. A closed drainage part 91 is preferable from the viewpoint of preventing the drainage from contaminating other places. The drainage part 91 may be, for example, a soft bag, and can contain the liquid discharged in the process of concentrating the ascites in the concentrator 12. During the connection check, the drainage part 91 may contain a liquid such as saline or water, or a gas such as air, that has passed through the concentrator 12.

[0087] The flow path 18 connects the treated bag 13 and the flow path 15. One end of the flow path 18 is connected to the treated bag 13. The other end of the flow path 18 may be connected to the flow path 15 between the valve 50 and the pump 51. The flow path 18 may be provided with a valve 70 that opens and closes the flow path 18.

[0088] In addition, for example, a flexible tube may be used for the 0th flow path 19a, the 1st flow path 19b, the 2nd flow path 19c, the 3rd flow path 19d, and the flow paths 14 to 18. The flexible tube may differ in at least one of the flow path cross-sectional area, the flow path length, the flow path wall thickness, and the constituent material for each flow path. This difference may change the flow path resistance for each flow path. For example, at least one of the flow path cross-sectional area, the flow path length, the flow path wall thickness, and the constituent material may be different in at least a part of the second flow path 19c and the third flow path 19d. This makes it possible to adjust the distribution ratio of the flow rate from the flow path connecting portion 19e to the second flow path 19c and the flow rate from the flow path connecting portion 19e to the third flow path 19d. Specifically, in order to make the flow path resistance of the second flow path 19c smaller than that of the flow path 19d, for example, the flow path length of the second flow path 19c may be shorter than the flow path length of the flow path 19d. Also, the flow path wall thickness of the second flow path 19c may be larger than the flow path wall thickness of the flow path 19d.

[0089] 1A, the filter 11 and the concentrator 12 may share a single drainage part 82. For example, as shown in FIG. 1D, the second flow path 19c may have a branch point 19f, and the fourth flow path 17 may be connected to the branch point. The fourth flow path 17 may have a backflow prevention part 65.

[0090] Fig. 4H shows an example of the configuration of the portion below the 0th flow path 19a in the embodiment shown in Fig. 1D. The embodiment shown in Fig. 4H differs from the embodiment shown in Fig. 4G in that the second flow path 19c has a branch point 19f. The other configurations are the same as those described in Fig. 4G, so descriptions of overlapping parts will be omitted.

[0091] Fig. 4J shows an example of the configuration of the fourth flow path 17 in the embodiment shown in Fig. 1D. The embodiment shown in Fig. 4J differs from the embodiment shown in Fig. 4I in that the fourth flow path 17 is connected to a branch point 19f of the second flow path 19c instead of being connected to the drainage portion 91.

[0092] In the example shown in Figures 4H and 4J, the fourth flow path 17 through which the waste liquid from the concentrator passes is connected to the branch point 19f. This allows the waste liquid from the concentrator 12 to flow to the waste liquid section 82 via the flow path connection section 19. The connection port 84b, which is the end of the second flow path 19c, is open to air before being connected to the first connection port 84a. The first connection port 84a is connected to a pressure gauge to measure the internal pressure of the second flow path.

[0093] 4K and 4L are partial enlarged views of the flow path circuit 20 of the processing system 1. Fig. 4K shows a state in which the concentrator 12, the treated bag 13, the physiological saline bag 24, etc. are not connected to the flow path circuit 20, and the connectors 21 connected to these components are connected to each other. Fig. 4L shows a state in which the concentrator 12, the treated bag 13, etc. are connected to the flow path circuit 20.

[0094] 4K is a diagram showing a schematic configuration of the flow path circuit 20, whereas Fig. 4L is a diagram showing a state in which the flow path circuit 20 is installed on a guide panel 151. By installing the flow path 20 along the guide panel 151, the user can easily configure the flow path without making a mistake.

[0095] The flow paths constituting the flow path circuit 20 may have connectors 21 at each end. The flow paths constituting the flow path circuit 20 may have marks 22 for clearly indicating the connection points to the on-off valves (valves). This makes it easier to install the on-off valves (valves) in appropriate positions. In addition, the flow paths constituting the flow path circuit may have marks 23, such as colors, for indicating the connection destinations to each device, filter, concentrator, etc. This allows the user to easily confirm the connection destinations based on the marks 23.

[0096] In addition, the physiological saline bag 24 may be of a type that is connected by a needle or a type that is connected by a connector. In Fig. 4K, the flow path 25 may be provided with both a needle 25a and a connector 25b at the tip so that either type can be connected. The configuration that includes both the needle 25a and the connector 25b may be similar to that shown in Fig. 4E. The flow path 25 may be provided with a valve 25c.

[0097] The physiological saline bag 24 is connected to the flow path 25, and by driving the pump 51, the physiological saline can be supplied to the filter 11 through the flow paths 25 and 15. This makes it possible to wash the filter 11.

[0098] The flow path circuit 20 shown in FIG. 4L has a tube 150 and a panel 151 that holds a portion of the tube 150.

[0099] The tube 150 of the flow path circuit 20 is soft and flexible, and is made of, for example, transparent polyvinyl chloride.

[0100] The panel 151 is made of a hard resin or the like. The material of the panel 151 includes a resin containing any one of ABS, PC (polycarbonate), PVC (polyvinyl chloride), PS (polystyrene), PP (polypropylene), POM (polyacetal), PE (polyethylene), PMMA (polymethyl methacrylate), SAN (styrene-acrylonitrile), and PA (polyamide). The panel 151 is formed into a thin, substantially rectangular plate shape by, for example, injection molding. The panel 151 is, for example, 500 cm 2 Less than 400cm, preferably 2 It has the following floor area:

[0101] The tubes 150 of the flow path circuit 20 are arranged along the panel surface of the panel 151. For example, some of the tubes 150, such as the flow paths 15, 16, 18, and 25, are arranged on the panel 151. The tubes 150 protrude outward from the outer periphery R of multiple sides of the panel 151. In this embodiment, the outer periphery R is a portion within 10 cm from the outer edge of the panel 151. The tubes 150 protrude outward from multiple points of the panel 151, for example, 10 or more points. The tubes 150 protrude outward from the panel 151 by 25 cm or more, preferably 35 cm or more. When the flow path circuit 20 is transferred, the portions of the tubes 150 protruding outward from the panel 151 may be bundled together.

[0102] The tube 150 of the flow path circuit 20 is held at a plurality of points on the panel 151. The outer peripheral portion R1 of the panel 151 is provided with a locking portion 160 that fits and locks the tube 150 from one direction along the panel surface and presses the front side surface of the tube 150 in the fitting direction, a pressing portion 161 that presses the rear side surface of the tube 150 locked to the locking portion 160 in the fitting direction, and a groove portion 162 that houses and holds the tube 150 locked to the locking portion 160 along the extension direction of the tube 150.

[0103] Since tube 150 of flow path circuit 20 protrudes from outer periphery R of panel 151 in multiple directions to the outside of panel 151, it is possible to reduce the possibility of erroneous installation of each tube 150 to the body fluid treatment device 2. When tube 150 of flow path circuit 20 protrudes from panel 151 in multiple directions, tube 150 is more likely to be subjected to external force; however, by holding tube 150 with locking portion 160, holding portion 161, and groove portion 162 in such a case, it is possible to prevent tube 150 from coming off.

[0104] The tubes 150 of the flow path circuit 20 extend outside from the panel 151 by more than 25 cm, and the proportion of the tubes 150 that are not fixed to the panel 151 becomes relatively large, making the tubes 150 susceptible to external forces. In such a case, however, it is very effective to provide the locking portion 160, the retaining portion 161 and the groove portion 162 on the outer periphery R1 of the panel 151.

[0105] Panel 151 has a surface area of ​​500 cm 2 Since the panel 151 is small, the amount of material used for the panel 151 can be reduced while the panel 151 can be attached to a small device and the packaging form can be made small. Here, even in the case of the panel 151 which has a small planar area and which is inherently prone to detachment of the tube 150 of the flow path circuit 20 due to an external force, by holding the tube 150 with the locking portion 160, the holding portion 161, and the groove portion 162, the tube 150 can be effectively prevented from coming off the panel 151 without increasing the portion for holding the tube 150.

[0106] Although the preferred embodiment of the present invention has been described above with reference to the accompanying drawings, the present invention is not limited to such an example. It is clear that a person skilled in the art can come up with various modified or altered examples within the scope of the ideas described in the claims, and it is understood that such examples also naturally belong to the technical scope of the present invention.

[0107] 2. Connection check Next, a flow chart of the connection check using the change in the line pressure will be described below. An example of the flow chart of the connection check is shown in FIG.

[0108] In step S11, the control unit 86 increases the pressure applied to the liquid filled in the 0th flow path 19a by the pump 51 or the like while keeping the valve 81 closed. At this time, the second pressure measurement unit 88 may detect the pressure applied to the liquid filled in the 0th flow path 19a.

[0109] In step S12, the control unit 86 transmits pressure to the second flow path 19c by controlling the pressurizing unit 90 to open the valve 81. The control unit 86 may control the pressurizing unit 90 to open the valve 81 when the pressure applied to the liquid filled in the 0th flow path 19a measured by the second pressure measuring unit 88 exceeds a threshold value. At this time, the second pressure measuring unit 88 may detect a decrease in the internal pressure of the 0th flow path 19a.

[0110] In step S13, the checking unit 85 measures the change in the pressure in the second flow path 19c from the time when the valve 81 is opened by the first pressure measuring unit 87. Then, in step S14, the checking unit 85 performs a connection check based on the change in the pressure in the second flow path 19c. For example, the checking unit 85 may detect that the second flow path 19c is connected when a pressure increase and decrease of at least a certain level is recognized in the pressure in the second flow path 19c, or may detect that the second flow path 19c is connected when the maximum pressure in the pressure in the second flow path 19c is at least a certain level.

[0111] Fig. 3A shows a connection check in which the pressure in the second flow path 19c is measured once, but in the connection check, the pressure in the second flow path 19c may be measured multiple times. Fig. 3B shows an example of a flowchart of a connection check in which the pressure in the second flow path 19c is measured multiple times.

[0112] For example, in a connection check, the checking unit 85 may measure the internal pressure of the second flow path 19c measured by the first pressure measuring unit 87 and / or measure the difference in the internal pressure of the second flow path 19c before and after pressurization measured by the first pressure measuring unit 87 multiple times in response to the pressurization unit 90 pressurizing the first flow path 19b, and may determine that the second flow path 19c is connected to the first connection port 84a for measuring the first pressure based on the results of the multiple measurements.

[0113] In addition, during the connection check, the checking unit 85 may change the pressurizing pressure applied by the pressurizing unit 90 and perform multiple checks to see whether the second flow path 19c is connected to the first connection port 84a for measuring the first pressure, and during the connection check, the checking unit 85 may determine that the second flow path 19c is connected to the first connection port 84a for measuring the first pressure based on the results of the multiple checks.

[0114] Steps S21, S22, and S23 may be the same as steps S11, S12, and S13. In the flowchart shown in Fig. 3B, in step S24, the check unit 85 performs a connection check based on a change in the pressure in the second flow path 19c, and ends the process if it is determined that the second flow path 19c is connected.

[0115] On the other hand, if it is determined in step S24 that the check unit 85 is not connected, in step S25, the check unit 85 performs a connection determination based on the pressurized pressure in step S21. Specifically, when the pressurized pressure in step S21 is equal to or greater than a predetermined value, the check unit 85 may determine that there is no connection. Even though the pressurized pressure in step S21 is equal to or greater than a predetermined value, a predetermined pressure change is not observed in the pressure inside the second flow path 19c, so that it can be determined that there is no connection.

[0116] Furthermore, when the pressurizing pressure in step S21 by the check unit 85 is less than a predetermined value, the control unit 86 may control the pressurizing unit 90 to further increase the pressure in the 0th flow path 19a and repeat steps S21, S22, S23, and S24. In this manner, by increasing the pressure in the 0th flow path 19a and repeating the connection check, the accuracy of the connection check tends to be further improved.

[0117] In addition, the check unit 85 may detect that the second flow path 19c is connected when an increase and decrease in the pressure inside the second flow path 19c is observed to be greater than or equal to a certain level, or may detect that the second flow path 19c is connected when the maximum value of the pressure inside the second flow path 19c is greater than or equal to a certain level.

[0118] With the above-described processing system, it is possible to easily check whether the pressure measuring unit is connected by detecting a change in the pressure inside the second flow path 19c. [Industrial Applicability]

[0119] The treatment system of the present invention has industrial applicability as a treatment system for treating blood and / or body cavity fluid. [Explanation of symbols]

[0120] 1... processing system, 2... body fluid processing device, 10... processing bag, 10a... hook hole, 10b... mesh part, 10c... pipeline, 10d... end, 10e... notch, 10f... connector, 10g... pipeline, 10h... connector, 10i... ascites collection line, 10j... connector, 10k... connector, 10l... regulator, 10m... chamber, 10n... port, 11... filter, 11a... fluid passage, 11b... fluid passage, 11c... fluid passage, 11d... fluid passage, 12... concentrator, 12a... fluid passage, 12b... fluid passage, 12c... fluid passage, 12d... fluid passage, 13... processed bag, 13a... Hook hole, 13b...pipeline, 13c...pipeline, 13d...connector, 13e...connector, 13f...port, 13g...port, 14...flow path, 14a...connector, 14b...connector, 14c...plastic needle, 14d...cap, 14e...mark, 14f...mark, 14g...connector, 15...flow path, 16...flow path, 17...fth flow path, 17a...connector, 17b...connector, 17c...connector, 17d...mark, 18...flow path, 19...flow path connection, 19a...0th flow path, 19aa...connector, 19ab...mark, 19ac...mark, 19ad...branch flow path, 19ae...branch flow path, 1 9af...connector, 19ag...connector, 19b...first flow path, 19c...second flow path, 19ca...drip chamber, 19d...third flow path, 19da...connector, 19e...flow path connection part, 19f...branch point, 20...flow path circuit, 21...connector, 22...mark, 23...mark, 24...physiological saline bag, 25...flow path, 25a...needle, 25b...connector, 30...filtration membrane, 30a...space (internal space of hollow fiber membrane), 30b...space (external space of hollow fiber membrane), 40...concentration membrane, 40a...space (inner space of hollow fiber membrane), 40b...space (outer space of hollow fiber membrane), 41...valve, 45...flow path, 45 a...mark, 45b...drip chamber, 46...connection port, 50...valve, 51...pump, 52...drip chamber, 53...introduction section, 60...pump, 65...backflow prevention section, 70...valve, 81...valve, 82...drainage section, 82a...hook hole, 82b...pipeline, 82c...pipeline, 82d...connector, 82e...cock, 83...second connection port, 84a...first connection port, 84b...connection port, 85...check section, 86...control section, 87...first pressure measurement section, 88...second pressure measurement section, 89...output section, 90...pressurization section, 91...drainage section, 100...information processing device, 111...processor,112: storage device, 114: input device, 115: output device, 130: storage section, 150: tube, 151: guide panel, 160: engagement section, 161: holding section, 162: groove section,

Claims

1. 1. A treatment system for treating blood and / or body cavity fluids, comprising: A filter and A pressurizing unit including a pump and a valve; A flow path connection portion; A zeroth flow path connecting the drain outlet of the filter and the valve; A first flow path connecting the valve and the flow path connection portion; a second flow path connecting the flow path connection portion and a first connection port for measuring a first pressure; a third flow path connecting the flow path connection portion and a drainage portion that stores the drainage flowing out from the drainage outlet; a check unit that checks the connection between the first connection port for measuring the first pressure and the second flow path; a first pressure measuring unit configured to measure a pressure in the second flow path connected to the first connection port for measuring the first pressure; A control unit that controls the pressurizing unit, the control unit controls the pressurizing unit to pressurize the liquid filled in the zeroth flow path with the valve closed and then open the valve; The check unit performs the connection check based on a pressure in the second flow path that is pressurized due to the valve being opened and that is measured by the first pressure measurement unit. Processing system.

2. The first pressure measurement unit measures the pressure in the second flow path based on the timing when the valve changes from a closed state to an open state. The processing system of claim 1 .

3. The drainage part of a closed system is connected to the third flow path. The processing system of claim 1 .

4. In the connection check, the checking unit determines that the second flow path is connected to the first connection port for measuring the first pressure when the internal pressure of the second flow path measured by the first pressure measuring unit is equal to or greater than a specified value. The processing system of claim 1 .

5. The check unit performs the connection check based on the internal pressure of the second flow path before and after the pressurization measured by the first pressure measurement unit. The processing system of claim 1 .

6. In the connection check, the checking unit determines that the second flow path is connected to the first connection port for measuring the first pressure when a difference between an internal pressure of the second flow path before and after the pressurization measured by the first pressure measuring unit is equal to or greater than a specified value. The processing system of claim 1 .

7. In the connection check, the checking unit measures the pressure in the second flow path measured by the first pressure measuring unit and / or measures a difference in the pressure in the second flow path before and after the pressurization measured by the first pressure measuring unit a plurality of times, and determines that the second flow path is connected to the first connection port for measuring the first pressure based on the results of the plurality of measurements. The processing system of claim 1 .

8. During the connection check, the checking unit changes the pressurizing pressure applied by the pressurizing unit and checks a plurality of times whether the second flow path is connected to the first connection port for measuring the first pressure, In the connection check, The checking unit determines, based on the multiple confirmation results, that the second flow path is connected to the first connection port for measuring the first pressure. The processing system of claim 1 .

9. At least one of a flow path cross-sectional area, a flow path length, a flow path wall thickness, and a constituent material is different in at least a part of the second flow path and the third flow path. The processing system of claim 1 .

10. A gas is sealed in a portion of the second flow path. The processing system of claim 1 .

11. The pressurizing unit has a second pressure measuring unit that measures the pressurizing pressure. The processing system of claim 1 .

12. a concentrator indirectly or directly connected to the filter; a fourth flow path for discharging the effluent removed by the concentrator; a backflow prevention portion provided in the fourth flow path; A branch point is provided in the second flow path, The fourth flow path is connected to the branch point. The processing system of claim 1 .

13. An output unit that displays a result of the connection check is further provided. The processing system of claim 1 .

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