Long-lasting lubricating composition

Abstract

Disclosed herein is an aqueous lubricating composition. The aqueous lubricating composition may comprise at least one part or extract from okra plant species and / or linseed plant species. Also disclosed herein are articles comprising the aqueous lubricating composition, possible applications and uses of the aqueous lubricating composition, and possible synthesis methods.

Description

[Technical field]

[0001] CROSS-REFERENCE TO RELATED APPLICATIONS This application claims priority from Australian Provisional Patent Application No. 2022 / 901194, filed May 5, 2022, and U.S. Provisional Patent Application No. 63 / 222,883, filed July 16, 2021, the contents of which are incorporated by reference in their entireties herein.

[0002] The present disclosure relates to an aqueous long-lasting lubricating composition.Disclosed herein is a personal aqueous lubricating composition, comprising at least one part or extract from okra plant species and / or linseed plant species.In addition, disclosed herein is an article comprising the aqueous long-lasting lubricating composition, the possible use of the aqueous long-lasting lubricating composition, and a method of synthesis. [Background technology]

[0003] Silicone-based personal lubricants are well known for their lubricating and long-lasting properties compared to water-based lubricants.However, one problem with silicone-based lubricants is that they do not dry and do not react directly with water, which means that they may not be easily washed off, whether they come into contact with sheets or body parts.As such, silicone-based lubricants may cause stains, for example, on bedding.Removal of silicone-based lubricants may also be difficult.The lack of easy removal may require laborious cleaning, the need for soap (to help solubilize the formulation), and / or the need to launder articles such as bedding.

[0004] Additionally, these types of compositions tend to remain in the vagina until the silicone-based lubricant is expelled, which may take a day or more, so individuals prone to frequent yeast infections may want to avoid using silicone-based lubricants.

[0005] Although water-based compositions can be used, these types of compositions have known problems such as drying too quickly compared to silicone-based compositions, providing insufficient lubrication, and potentially causing discomfort to users of the water-based compositions, among other issues.

[0006] Any discussion of documents, acts, materials, devices, articles or the like which has been included in this specification should not be construed as an admission that any or all of such matters form part of the prior art base or were common general knowledge in the art relevant to the present disclosure because they existed prior to the priority date of each claim of this application. Summary of the Invention

[0007] Previously, water-based personal lubricating compositions may dry too quickly after application to surfaces such as skin, especially compared to silicone-based lubricants.In addition, previously known water-based lubricating compositions may not provide the long-lasting lubrication provided by silicone-based lubricants.One objective of the present disclosure is to provide a personal water-based lubricating composition that may have one or more of the following characteristics: likely to be easily washed with water (e.g., from body parts or items); avoid or minimize staining (e.g., on bed sheets); be based on or contain a majority of natural-based ingredients; and / or provide long-lasting lubrication comparable to silicone-based lubricating compositions.

[0008] In addition, because many people prefer the silky feel and moisturizing effect on the skin provided by silicone-based lubricating compositions over water-based lubricating compositions, another possible objective is to provide a personal water-based lubricating composition that at least partially replicates these beneficial attributes of silicone-based compositions.

[0009] Silicone-based lubricants are Newtonian fluids, and viscosity is independent of shear rate. In addition to having low viscosity and low elasticity contribution, silicone-based lubricants can flow without force, and therefore have a tendency to drip (e.g., leak) from tube packaging. On the other hand, the personal aqueous lubricant composition described herein, in one embodiment, is preferably a non-Newtonian fluid, and exhibits shear thinning behavior in which viscosity decreases as shear rate increases, and thus its ability to spread easily on skin when applied (at high shear rate) and not drip (leak) from tube packaging (at very low shear rate). The flow behavior of the personal aqueous lubricant composition can be designed, among other things, by adjusting the type and / or concentration of one or more of the components to at least minimize or reduce leakage problems.

[0010] In some embodiments, potential advantages of the disclosure herein may include, but are not limited to, one or more of the following: The compositions included are water-based (e.g., reducing the number of chemicals that may react with an individual's skin and cause irritation and / or allergic reactions - hypoallergenic) The composition contains natural ingredients Similar to the comparative silicone-based personal lubricant, the composition provides: Silky texture and / or ○Lubricating and long-lasting effects The composition includes a high percentage of ingredients of natural origin (in some instances, greater than about 80%, e.g., greater than about 95% of the ingredients may be of natural origin). ●Non-adhesive Does not promote and / or reduces the growth of mold and / or yeast -Easy to wash off (especially compared to silicone or oil-based lubricants) Safe application and use with toys and / or contraceptive devices Non-hormonal Reduced, substantially no, or no residue after application to items, surfaces, and / or individuals Reduced risk of staining items compared to silicone or oil-based lubricants The generation of non-Newtonian fluids, and / or - Minimal leakage, substantially no leakage or no leakage from any packaging (e.g., tube packaging) containing the compositions described herein.

[0011] Additional advantages from the present disclosure may include one or more of the following: Personal lubricant formulations for penile and / or vaginal application Compositions that are compatible with natural rubber and / or polyisoprene articles such as condoms A pH-balanced, paraben-free composition; and / or Compositions approved for gynecological and / or dermatological use.

[0012] In a first aspect, disclosed herein is a personal aqueous lubricating composition comprising at least one of a portion or extract from an okra plant species, and a portion or extract from a flaxseed plant species.

[0013] In a second aspect, disclosed herein is a massage gel or liquid comprising a personal aqueous lubricating composition according to the first aspect.

[0014] In a third aspect, disclosed herein is a coating comprising the personal aqueous lubricating composition according to the first aspect.

[0015] In a fourth aspect, disclosed herein is an article comprising the personal aqueous lubricating composition according to the first aspect, or the coating of the third aspect.

[0016] In a fifth aspect, disclosed herein is the use of a personal aqueous lubricating composition according to the first aspect as a massage gel or liquid.

[0017] In a sixth aspect, disclosed herein is the use of a personal aqueous lubricating composition according to the first aspect as a coating.

[0018] In a seventh aspect, disclosed herein is the use of a personal aqueous lubricating composition according to the first aspect as a lubricant, wherein the lubricant composition is applied directly to at least a portion of the skin of an individual.

[0019] It will be understood that embodiments of each aspect of the disclosure may be equally applied to each other aspect, mutatis mutandis. [Brief description of the drawings]

[0020] It will be understood that various embodiments disclosed herein may be utilized, some examples of which are described herein with reference to the following drawings:

[0021] [Figure 1] 4. Flow curves for silicone-based lubricants and water-based lubricants as defined herein. [Diagram 2] Measured coefficient of friction for selected lubricants and water (average of 13 replicates). [Diagram 3] Image A) is a comparison plot of the average coefficient of friction for selected lubricants and water, and Image B) is an interval plot of the measured coefficient of friction for selected lubricants and water. [Figure 4] The retraction force of the selected composition. [Diagram 5] Image A) is a comparison of the average determined axial forces (N) for selected lubricants and water, and image B) is an interval plot of the measured axial forces for selected lubricants and water. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0022] General Definitions and Terminology With respect to the definitions provided herein, unless otherwise stated or implied from the context, the defined terms and phrases include the meanings provided. In addition, unless expressly stated otherwise or clear from the context, the following terms and phrases do not exclude the meaning that the term or phrase would have acquired by one of ordinary skill in the relevant art. The definitions are provided to help describe certain embodiments and are not intended to limit the claimed invention, since the scope of the invention is limited only by the claims.

[0023] As used herein, "lubricating composition," "lubricating composition," "personal lubricating composition," "composition," "aqueous lubricating composition," and "personal aqueous lubricating composition" may be used interchangeably unless otherwise indicated or clear from the context.

[0024] Recipients of the recited lubricating compositions are referred to herein by the interchangeable terms "recipient," "individual," and / or "subject." These terms are used interchangeably and refer to human beings of any gender, unless otherwise indicated or clear from the context.

[0025] Unless otherwise stated, all publications discussed and / or referenced herein are incorporated herein in their entirety.

[0026] Unless otherwise required by context, singular terms shall include the plural and plural terms shall include the singular. Throughout this disclosure, unless otherwise specified or the context requires otherwise, reference to a single step, composition of matter, group of steps, or group of compositions of matter shall be construed to include one and more than one (i.e., one or more) of that step, composition of matter, group of steps, or group of compositions of matter. Thus, as used herein, the singular forms "a," "an," and "the" include plural aspects unless the context clearly indicates otherwise. For example, reference to "a" includes two or more as well as the singular, reference to "an" includes two or more as well as the singular, reference to "the" includes two or more as well as the singular, etc.

[0027] Those skilled in the art will understand that the disclosure herein is susceptible to variations and modifications other than those specifically described. It is to be understood that the disclosure includes all such variations and modifications. The disclosure also includes all of the examples, steps, features, methods, compositions, formulations, and processes referred to or shown in this specification, individually or collectively, and any and all combinations, or any two or more of such steps or features.

[0028] The term "and / or," e.g., "X and / or Y," is understood to mean either "X and Y" or "X or Y," and is interpreted as explicitly endorsing both meanings or either meaning.

[0029] Unless otherwise indicated, terms such as "first," "second," and the like are used herein merely as labels, and are not intended to impose any sequential, positional, or hierarchical requirements on the items to which they refer. Moreover, a reference to a "second" item does not require or preclude the presence of a lower-numbered item (e.g., the "first" item) and / or a higher-numbered item (e.g., the "third" item).

[0030] As used herein, the phrases "at least one," "one or more," when used with a list of items, mean that different combinations of one or more of the listed items may be used, or that only one of the items in the list may be required. An item may be a specific object, thing, or category. In other words, "at least one" or "one or more" means that any combination of items or any number of items from the list may be used, but not all items in the list may be required. For example, "at least one of item A, item B, and item C" may mean item A; item A and item B; item B; item A, item B, and item C; or item B and item C. In some cases, "at least one of item A, item B, and item C" may mean, for example, but not limited to, two of item A, one of item B, and ten of item C; four of item B, and seven of item C; or some other suitable combination.

[0031] It should be understood that certain features that are, for clarity, described herein in the context of separate embodiments, may also be provided in combination in a single embodiment. Conversely, various features that are, for brevity, described in the context of a single embodiment, may also be provided separately or in any subcombination.

[0032] Throughout this specification, various aspects and components of the disclosure may be presented in a range format. The range format is included for convenience and should not be construed as an inflexible limitation on the scope of the disclosure. Thus, a description of a range should be considered to have all possible subranges specifically disclosed, as well as individual numerical values ​​within that range, unless specifically indicated otherwise. For example, a description of a range of 1 to 5 should be considered to have specifically disclosed subranges such as 1 to 3, 1 to 4, 1 to 5, 2 to 4, 2 to 5, 3 to 5, etc., as well as individual and partial numbers within the recited range, such as 1, 2, 3, 4, 4.5, and 5, unless an integer is required or is implied by context. This applies regardless of the breadth of the disclosed range. When specific values ​​are required, they are indicated in the specification.

[0033] Throughout this specification the term "comprise" or variations such as "comprises" or "comprising" will be understood to imply the inclusion of a stated element, integer, or step, or group of elements, integers, or steps, and not the exclusion of any other element, integer, or step, or group of elements, integers, or steps.

[0034] Throughout this specification, the term "consisting essentially of" is intended to exclude elements that would materially affect the properties of the claimed composition, method, or process.

[0035] The terms "comprising," "comprise," and "comprises," in all instances, are intended to be optionally interchangeable with the terms "consisting essentially of," "consist essentially of," "consist essentially of," "consisting of," "consist of," and "consists of," respectively.

[0036] As used herein, the term "about" encompasses a tolerance of 10% in any value connected to the term.

[0037] As used herein, "weight percent" may be abbreviated as "wt%" or "wt.%." Weight percent may be w / w or w / v unless specifically indicated otherwise or clear from the context.

[0038] In some embodiments, "lubrication" may be considered as the separation of multiple surfaces (which may include one or more parts of the human body) that are otherwise in contact with one another, by a lubricant such that, when the surfaces are moving relative to one another, frictional resistance is reduced at the interfaces associated with such movement compared to the frictional resistance within the same system in the absence of the lubricant. In some embodiments, lubrication utilizing the compositions defined herein may prevent and / or reduce wear, irritation, heat generation, and / or damage to the surfaces due to such movement.

[0039] As used herein, personal lubricants include specialized lubricants (including massage gels or liquids) that help reduce friction with body tissues. Personal lubricants can be used to provide lubrication or slippage during sexual activity. For example, personal lubricants can be used to increase pleasure and / or reduce pain during sexual intercourse and can help reduce vaginal dryness. In medicine, personal lubricants can be used for gynecological examinations and the like. Personal lubricating compositions as defined herein also include formulations that can be used as massage gels or massage liquids.

[0040] As used herein, "aqueous-based" means that the lubricating composition has water as the primary solvent and / or component.

[0041] As used herein, "natural ingredients" refers to ingredients that occur in nature, including those of natural origin. In a preferred embodiment, the natural ingredients are obtained from renewable resources. As used herein, "natural ingredients", e.g., cosmetic ingredients, are from plants, animals, microorganisms, or minerals, including those obtained from these sources by: Physical processes (e.g. grinding, drying, distillation) Fermentation reactions that occur in nature and result in naturally occurring molecules, and • Other preparation procedures, including conventional ones (e.g. extraction using solvents), without any deliberate chemical modification. Unless otherwise defined, the following materials and materials derived therefrom shall be considered to fall under the general heading of natural origin: a) Plants, including fungi and algae b) Minerals c) Animals, and d) Microorganisms. Ingredients derived from fossil fuels are excluded from this definition. In one or more embodiments, the natural ingredients described herein are plant-based or derived from plants. In another embodiment, the one or more natural ingredients are in accordance with ISO16128-2:2017.

[0042] As used herein, the phrase "transparent, substantially transparent, or translucent" means that the composition appears homogenous, lacks visible precipitated solids, and is not opaque or cloudy. Additionally, as used herein, "colorless" means the lack of any perceptible or visually measurable color or hue, i.e., the substantial absence of all color, as may be determined via suitable means, such as spectrophotometric measurement.

[0043] As used herein, a "non-Newtonian composition" or "non-Newtonian fluid" refers to a composition or fluid whose viscosity is variable based on an applied stress, i.e., the viscosity changes as the flow rate gradient changes.

[0044] As used herein, "non-tacky" means that a composition, such as a lubricant, applied to an article exhibits reduced or negligible adhesive or cohesive properties such that the portion of the article containing the lubricant agglomerates and / or the cohesion between multiple articles is reduced or negligible. Conversely, "tacky" as defined herein means that the composition exhibits enhanced adhesion or tack such that the composition enhances the cohesion of the article or portions thereof.

[0045] lubricating composition Components Disclosed herein are personal aqueous lubricating compositions, such as personal aqueous lubricating compositions comprising at least one of a portion or extract from an okra plant species, and a portion or extract from a flaxseed plant species.

[0046] The aqueous lubricating composition may be in the form of a liquid or a gel. In one embodiment, the aqueous lubricating composition is in the form of a liquid. In one embodiment, the aqueous lubricating composition is in the form of a gel.

[0047] In one embodiment, at least one component of the lubricating composition is a natural ingredient, hi another embodiment, multiple components of the lubricating composition, for example, 2, 3, 4, 5, or more components, are natural ingredients.

[0048] The natural ingredient may be an extract derived from a plant (including fungi and / or algae) or at least a part of a plant. In one embodiment, the plant extract is an extract obtained directly from a plant, rather than a synthetic compound or composition. Unless otherwise defined, the term "plant" refers to a multicellular organism that typically grows in a permanent location, absorbs water and inorganic substances through its roots, and produces nutrients in its leaves by photosynthesis. As used herein, unless otherwise defined, the term "plant extract" or "extract" refers to any extract that can be obtained from a plant or any part thereof. The extract can be taken from any part of the plant, such as leaves, roots, flowers, seeds, fruits, bark, or parts thereof. The plant extract may be prepared from a single part of the plant, or from two or more parts of the plant. As used herein, a "plant extract" or "extract" does not consist of water alone.

[0049] The natural ingredients may be used in any form. For example, natural ingredients in the form of liquid, oil, gel, granules, powder, or mixtures thereof may be used to form the lubricating composition. The natural ingredients may be used directly from the plant or may be modified. For example, the natural ingredients may be processed, e.g., dried to remove at least a portion of the water (e.g., converted to a powder form). As used herein, unless otherwise defined, a "gel" is a non-fluid colloidal network that is expanded throughout its volume by a fluid. In one embodiment, the natural ingredient is a gum.

[0050] A component in the form of a powder may be a "dry" powder, which is substantially free of water, hi one embodiment, the powder has less than, or about, 10.0, 7.5, 5.0, 4.0, 3.0, 2.0, or 1.0% water by weight of the powder.

[0051] The natural ingredient may be mucilage obtained from a plant, or part thereof. As used herein, "mucilage" is a thick, viscous (i.e., "sticky") substance produced by plants that contains glycoproteins and exopolysaccharides.

[0052] The natural ingredients may be obtained by any process known in the art or may be obtained commercially.

[0053] The lubricating composition may include one or more components selected from, but not limited to, natural gums, hemicelluloses (such as xyloglucan, xylan, and mannan), pectins (e.g., from citrus fruits, apple, pear, gooseberry, etc.), glycogen, chrysolaminarin, derivatives thereof, and mixtures thereof.

[0054] As used herein, "gum" or "natural gum" refers to an exudation of a plant, such as a tree or shrub, that hardens when dry but is soluble or partially soluble in water.

[0055] Natural gums include non-cellulosic polysaccharides derived from botanical or plant sources, seaweed, or produced by bacterial fermentation. Non-limiting examples of natural gums derived from plants include, but are not limited to, Sclerotium gel or gum, Albizia gum, Aloe mucilage, beta glucan, chicle gum, dammar gum, fenugreek gum, glucomannan, guar gum, gum arabic (also called acacia gum), copal gum, gum ghatti, tragacanth gum, hakea gum, Hibiscus rosasinensis gum, honey locust gum, hupoo gum, karaya gum, kaya gum, Lepidium sativum gum, locust bean gum, mastic gum, Mimosa scabrella gum, Mimosa pudica gum, Okra gum, psyllium seed husk (also called ispaghula husk), spruce gum, Sterculia foetida gum, tamarind gum, tara gum, and derivatives of any of the above. Examples of natural gums derived from seaweed include, but are not limited to, alginic acid or alginic acid, fucoidan, and laminarin from brown seaweed, and agar and carrageenan from red seaweed.Non-limiting examples of natural gums produced by bacterial fermentation include xanthan gum, gellan gum, dextran, welan gum, diutan gum, pullulan, and derivatives thereof.

[0056] Examples of plant extracts, optionally in the form of a gum, that may be present in the lubricating composition may be one or more compositions selected from, but are not limited to, Abelmoschus esculentus (okra; e.g., as an extract or as a powder; CAS No. 84455-19-6 or CAS No. 91723-07-8); Sclerotium gum (e.g., Ami gum, CAS No. 39464-87-4); Xanthan gum (e.g., Keltrol® CG-T; CAS No. 11138-66-2); Limun Usitaissimum (e.g., flax, such as Limun Usitaissimum L gum; CAS No. 8001-26-1); Aloe (e.g., Glycine soja (soybean) oil, CAS No. 85507-69-3, and / or aloe barbadensis leaf extract, CAS No. 94349-62-8), and mixtures thereof.

[0057] The natural gums may be used in any form. For example, natural gums in the form of liquids, oils, gels, granules, powders, or mixtures thereof may be used to form the lubricating composition. The gums may be used directly from the plant or may be modified. For example, the gums may be processed, e.g., dried to remove at least a portion of the water, or may be diluted, e.g., diluted with water or a solvent containing water.

[0058] In one embodiment, the lubricating composition comprises only 1, 2, 3, 4, or 5 plant extracts.In one embodiment, the lubricating composition comprises at least 1, 2, 3, 4, or 5 plant extracts.

[0059] In one embodiment, at least one plant extract (e.g., from okra and / or flaxseed) comprises mucilage. In another embodiment, multiple plant extracts (e.g., from okra and / or flaxseed) comprise mucilage.

[0060] In one embodiment, at least one component of the lubricating composition is a natural gum, hi another embodiment, multiple components of the lubricating composition, for example, 2, 3, 4, 5 or more components, are natural gums.

[0061] One or more components of the lubricating composition (such as a portion of the okra or flaxseed and / or an extract of the okra or flaxseed) may be about, or at least about, 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, 3.0, 3.1, 3.2, 3.3, 3.4, 3.5, 3.6, 3.7, 3.8, 3.9, 3.1, 3.2, 3.3, 3.4, 3.5, 3.6, 3.8, 3.9, 3.1, 3.2, 3.3, 3.4, 3.5, 3.7, 3.8, 3.9, 3.1, 3.2, 3.3, 3.4, 3.5, 3.8, 3.9, 3.1, 3.2, 3.3, 3.4, 3.5, 3.5, 3.6, 3.7, 3.8, 3.9, 3.1, 3.2, 3.3, 3.4, 3.5, 3.8, 3.9, 3.1, 3.2, , 2.6, 2.7, 2.8, 2.9, 3.0, 3.1, 3.2, 3.3, 3.4, 3.5, 3.6, 3.7, 3.8, 3.9, 4.0, 4.1, 4.2, 4.3, 4.4, 4.5, 4.6, 4.7, 4.8, 4.9, or 5.0% w / w, or 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, 3.0, 3.1, 3.2, 3.3, 3.4, 3.5, 3.6, 3.7, 3.8, 3.9, 4.0, 4.1, 4.2, 4.3, 4.4, 4.5, 4.6, 4.7, 4.8, 4.9, or 5.0% w / v, or 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.2, 0.3, The lubricating oil may be present in the lubricating composition in an amount of 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0., 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, 3.0, 3.1, 3.2, 3.3, 3.4, 3.5, 3.6, 3.7, 3.8, 3.9, 4.0, 4.1, 4.2, 4.3, 4.4, 4.5, 4.6, 4.7, 4.8, 4.9, or 5.0% v / v.

[0062] One or more components of the lubricating composition, e.g., natural ingredients (e.g., natural gums), may be about, or at least about, 0.5, 1, 2, 2.5, 5, 7.5, 10, 12.5, 15, 17.5, 20, 22.5, 25, 27.5, 30, 32.5, 35, 37.5, or 40% w / w, or 0.5, 1, 2, 2.5, 5, 7.5, 10, 1 It may be present in the lubricating composition in an amount of 2.5, 15, 17.5, 20, 22.5, 25, 27.5, 30, 32.5, 35, 37.5, or 40% w / v, or 0.5, 1, 2, 2.5, 5, 7.5, 10, 12.5, 15, 17.5, 20, 22.5, 25, 27.5, 30, 32.5, 35, 37.5, or 40% v / v.

[0063] In one embodiment, in the lubricating composition, the non-water components constitute or consist of about or less than 60, 55, 50, 45, 40, 38, 36, 34, 32, 30, 28, 26, 24, 22, 20, 18, 16, 14, 12, 10, 8, 6, 4, or 2% w / w, or 60, 55, 50, 45, 40, 38, 36, 34, 32, 30, 28, 26, 24, 22, 20, 18, 16, 14, 12, 10, 8, 6, 4, or 2% w / v, or 60, 55, 50, 45, 40, 38, 36, 34, 32, 30, 28, 26, 24, 22, 20, 18, 16, 14, 12, 10, 8, 6, 4, or 2% v / v.

[0064] In one embodiment, at least one component of the lubricating composition is an extract from at least one of okra, flaxseed, and / or aloe.

[0065] In one embodiment, at least one component of the lubricating composition is a part of an okra, flax, and / or aloe plant, such as the leaves, roots, flowers, seeds, fruit, bark, or parts thereof, or an extract obtained from the leaves, roots, flowers, seeds, fruit, and / or bark of an okra, flax, and / or aloe plant.

[0066] In one embodiment, at least one component of the lubricating composition is from the okra plant species. In another embodiment, the okra plant species belongs to the Abemoschus genus. The okra plant species can be selected from, but is not limited to: Abelmoschus esculentus (also called Hibiscus esculentus), Abelmoschus caillei (also called West African okra), Abelmoschus manihot, Abelmoschus ficuneus, Abelmoschus moschatus, or any mixture of two or more of these species. In different parts of the world, it is known as Okra, Ochro, Okoro, Quimgombo, Quingumbo, Ladies Fingers, Gombo, Kopi Arab, Kacang Bendi, Bhindi (South Asia), Bendi (Malaysia), Bamia, Bamya, or Bamieh (Middle East), or Gumbo (Southern United States). In one embodiment, the extract is obtained from the okra fruit (pod) and / or okra seeds. In one embodiment, the lubricant composition comprises a component of or derived from the okra plant species, which may be, for example, Abelmoschus esculentus, as a powder, liquid, oil, gel, granules, or mixtures thereof. In another embodiment, the lubricant composition comprises at least a portion of an okra seed or an extract thereof, at least a portion of an okra fruit (pod) or an extract thereof, or a mixture thereof.

[0067] In one embodiment, the extract of okra (eg, from the okra fruit (pod) and / or seeds) includes okra mucilage.

[0068] In one embodiment, at least one component of the lubricating composition is from linseed (also known as linseed or flax), which is the seed of the plant of the genus Linum in the family Linaceae. The term "linseed" includes the seeds of about 150 plants, all of which are within the scope of the present invention. In one embodiment, the linseed is from one or more species selected from the following: Linum usitatissimum, Linum humile, Linum austriacum, Linum bienne, Linum angustifolium, Linum catharticum, Linum flavum, Linum grandiflorum, Adenolinum grandiflorum, Linum lewisii, Linum narbonense, Linum perenne, Linurn perenne var.lewisii, Linum pratense, and Linum trigynum, and mixtures thereof. In one embodiment, all varieties of all species are within the scope of the present invention. As used herein, flaxseed or flaxseed extract may be obtained from whole, crushed flaxseed flour, as well as ground and / or milled flaxseed. The flaxseed extract may be a gum. As used herein, flaxseed extract refers to components and / or parts of whole flaxseed. In one embodiment, the flaxseed extract comprises mucilage. In another embodiment, the flaxseed extract may comprise an oil obtained from flaxseed (or parts thereof). In one embodiment, the lubricant composition comprises components of the flaxseed plant species or components derived from the flaxseed plant species in the form of a powder, liquid, oil, gel, granules, or mixtures thereof, etc.

[0069] In one embodiment, at least one component of the lubricating composition is from an aloe plant species, which may be selected from, but is not limited to, Aloe vera, Aloe arborescens, Aloe aristata, Aloe dichotoma, Aloe nyeriensis, Aloe variegate, Aloe barbadensis, and Aloe wildii, or any mixture of two or more species thereof. In one embodiment, the lubricant composition includes an aloe component or an aloe-derived component, for example, as a powder, liquid, oil, gel, granule, or mixture thereof.

[0070] As used herein, the plant extract (e.g., okra extract and / or flaxseed extract) may include one or more of carbohydrates, proteins, dietary fibers (e.g., soluble and / or insoluble fibers), plant lignans, starches, sugars, fats, fatty acids (e.g., including at least one of myristic acid, pentadecylic acid, margaric acid, stearic acid, nonadecylic acid, behenic acid, elaidic acid, vaccenic acid, linoleylaidic acid, alpha-linolenic acid, palmitic acid, palmitoleic acid, olelic acid, linoleic acid, and mixtures thereof), phytosterols, and mixtures thereof. The plant extract may include another fatty acid that is a saturated fatty acid, a monounsaturated fatty acid, a diunsaturated fatty acid, a triunsaturated fatty acid, a tetraunsaturated fatty acid, a pentaunsaturated fatty acid, a hexaunsaturated fatty acid, or a mixture thereof.

[0071] As used herein, the plant extract (e.g., okra extract and / or flaxseed extract) may contain one or more amino acids selected from, but not limited to, alanine, arginine, aspartic acid, cysteine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, valine, and mixtures thereof.

[0072] The plant extract (e.g., okra extract and / or flaxseed extract) may contain omega-3 fatty acids, omega-6 fatty acids, or mixtures thereof. For example, the plant extract may contain at least one or more of alpha-linolenic acid, eicosapentaenoic acid, and / or docosahexanoic acid.

[0073] The plant extract (e.g., okra extract and / or flaxseed extract) may include one or more monosaccharides, polysaccharides, or mixtures thereof. The okra extract may include one or more of mannose, rhamnose, glucuronic acid, glucose, fucose, arabinose, galacturonic acid, galactose, xylose, and mixtures thereof.

[0074] The plant extract (e.g., okra extract and / or flaxseed extract) may contain protein and / or other minerals. Examples of minerals include, but are not limited to, calcium, potassium, phosphorus, selenium, sodium, magnesium, copper, iron, manganese, zinc, and mixtures thereof. The plant extract (e.g., okra extract and / or flaxseed extract) may contain one or more vitamins, such as, but not limited to, vitamin A, vitamin B1, vitamin B2, vitamin D, vitamin E, and mixtures thereof. The plant extract (e.g., okra extract and / or flaxseed extract) may contain arabinoxylan.

[0075] In one embodiment, the extract (e.g., okra and / or flaxseed extract) comprises, each independently, about, or at least about 0.1% w / w, 0.2% w / w, 0.3% w / w, 0.4% w / w, 0.5% w / w, 0.6% w / w, 0.7% w / w, 0.8% w / w, 0.9% w / w, 1% w / w, 2% w / w, It may be present in an amount of 3% w / w, 4% w / w, 5% w / w, 6% w / w, 7% w / w, 8% w / w, 9% w / w, 10% w / w, 11% w / w, 12% w / w, 13% w / w, 14% w / w, 15% w / w, 16% w / w, 17% w / w, 18% w / w, 19% w / w, 20% w / w, 25% w / w, or 30% w / w. In another embodiment, the extract (e.g., okra and / or flaxseed extract) comprises non-aqueous components, each independently, at about, or at least about, 0.1% w / v, 0.2% w / v, 0.3% w / v, 0.4% w / v, 0.5% w / v, 0.6% w / v, 0.7% w / v, 0.8% w / v, 0.9% w / v, 1% w / v, 2% w / v , 3% w / v, 4% w / v, 5% w / v, 6% w / v, 7% w / v, 8% w / v, 9% w / v, 10% w / v, 11% w / v, 12% w / v, 13% w / v, 14% w / v, 15% w / v, 16% w / v, 17% w / v, 18% w / v, 19% w / v, 20% w / v, 25% w / v, or 30% w / v.

[0076] In one embodiment, the total amount of non-aqueous components in the extract (e.g., okra and / or flaxseed extract) is about, or at least about, 0.1% w / w, 0.2% w / w, 0.3% w / w, 0.4% w / w, 0.5% w / w, 1% w / w, 2% w / w, 3% w / w, 4% w / w, 5% w / w, 6% w / w, 7% w / w, 8% w / w, 9% w / w / w, 10% w / w, 11% w / w, 12% w / w, 13% w / w, 14% w / w, 15% w / w, 16% w / w, 17% w / w, 18% w / w, 19% w / w, 20% w / w, 25% w / w, 30% w / w, 35% w / w, 40% w / w, 45% w / w, 50% w / w, 55% w / w, or 60% w / w. In another embodiment, the total amount of non-aqueous components in the extract (e.g., okra and / or flaxseed extract) is about, or at least about, 0.1% w / v, 0.2% w / v, 0.3% w / v, 0.4% w / v, 0.5% w / v, 1% w / v, 2% w / v, 3% w / v, 4% w / v, 5% w / v, 6% w / v, 7% w / v, 8% w / v, 9% w / v, 10% w / v, 12% w / v, 14% w / v, 16% w / v, 18% w / v, 19% w / v, 20% w / v, 21% w / v, 22% w / v, 23% w / v, 24% w / v, 25% w / v, 26% w / v, 27% w / v, 28% w / v, 29% w / v, 30% w / v, 31% w / v, 32% w / v, 33% w / v, 34% w / v, 35% w / v, 36% w / v, 37% w / v, 38% w / v, 39% w / v, 40% w / v, 40% w / v, 40% w / v, 41% w / v, 42% w / v, 43% w / v, 44% w / v, 45% w / v, 46% w / v, 47% w / v, 48% w / v, 40% w / v, 41% w / v, 42% w / v, 43% w / v, 44% w / v, 45% w / v, 46% w / v, 47% w / v, w / v, 10% w / v, 11% w / v, 12% w / v, 13% w / v, 14% w / v, 15% w / v, 16% w / v, 17% w / v, 18% w / v, 19% w / v, 20% w / v, 25% w / v, 30% w / v, 35% w / v, 40% w / v, 45% w / v, 50% w / v, 55% w / v, or 60% w / v.

[0077] A component of a lubricating composition may have or potentially have a single function or multiple functions in the lubricating composition, for example, a component may function as a humectant and / or preservative, or as a humectant thickener.

[0078] One or more components of the lubricating composition may be an emollient, for example a natural ingredient is an emollient, and in one embodiment provides a moisturizing, soothing, and / or softening sensation to at least a portion of the skin.

[0079] The lubricating composition may include at least one component that is a humectant, emollient, antioxidant, preservative, thickener, flavor / fragrance, pH adjuster, pH buffer, emulsifier, surfactant, emollient, moisturizer, cooling agent, and / or tingling agent, or mixtures thereof.

[0080] Suitable components may be identified by one of ordinary skill in the art with reference to appropriate materials, for example applicable standards, and potentially websites such as CosmeticsInfo.org.

[0081] Examples of humectants include, but are not limited to, 1,3-propanediol (CAS No. 504-63-2), hyaluronic acid or its salts (e.g., sodium hyaluronate, CAS No. 9067-32-7), flax extract (e.g., Limun Usitaissimum L gum, CAS No. 8001-26-1), okra extract (e.g., Abelmoschus Esculentus L. Moench, CAS No. 84455-19-6 or CAS No. 91723-07-8), aloe vera extract (e.g., Glycine Soja (Soybean) Oil, CAS No. 85507-69-3, and / or Aloe Barbadensis Leaf Extract, CAS No. 94349-62-8), and mixtures thereof.

[0082] The one or more wetting agents may be present in the lubricating composition in an amount (% w / w) of about, or at least about, 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, or 3.0. % w / w.

[0083] Examples of preservatives include, but are not limited to, 1,3-propanediol (e.g., CAS No. 504-63-2), lactic acid (e.g., CAS No. 50-21-5), citric acid (e.g., CAS No. 77-29-9), tartaric acid (e.g., CAS No. 87-69-4), gluconic acid (e.g., CAS No. 526-95-4), potassium sorbate (e.g., CAS No. 24634-61-5), sorbic acid (e.g., CAS No. 110-44-1), sodium lactate (e.g., CAS No. 867-56-1), benzoic acid (e.g., CAS No. 65-85-0), and mixtures thereof.

[0084] The one or more preservatives may be present in the lubricating composition in an amount (% w / w) of about, or at least about, 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, or 3.0% w / w.

[0085] Examples of thickening agents include, but are not limited to, sclerotium gum (e.g., CAS No. 39464-87-4), hydroxyethylcellulose (e.g., CAS No. 9005-62-0), xanthan gum (e.g., CAS No. 11138-66-2), flax extract (e.g., Limun Usitaissimum L gum, CAS No. 8001-26-1), okra extract (e.g., Abelmoschus Esculentus L. Moench, CAS No. 84455-19-6, or CAS No. 91723-07-8), aloe vera extract (e.g., Glycine Soja (Soybean) Oil, CAS No. 85507-69-3, and / or Aloe Barbadensis Leaf Extract, CAS No. 94349-62-8), carboxypolymethylene polymers, and mixtures thereof.

[0086] The one or more thickening agents may be present in the lubricating composition in an amount (% w / w) of about, or at least about, 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, or 3.0% w / w.

[0087] Examples of antioxidants include, but are not limited to, benzoic acid (eg, CAS No. 65-85-0).

[0088] water The lubricating compositions disclosed herein are aqueous. The water may be deionized water. The water may be referred to as "aqua". The water may be purified water. In one embodiment, the water is pharmaceutical grade water, e.g., pharma- ceutically acceptable water according to the British Pharmacopoeia.

[0089] Water may be present in the lubricant composition in an amount of about, or at least about, 40, 42, 44, 46, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, or 96% w / w, or 40%, 42, 44, 46, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, or 96% w / w. It may be present in an amount of 6, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, or 96% w / v, or 40, 42, 44, 46, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, or 96% v / v.

[0090] Natural origin calculation In one embodiment, at least one component of the lubricating composition is a natural ingredient, hi another embodiment, at least two, three, or four components of the lubricating composition are natural ingredients.

[0091] In one embodiment, the selection of components of the lubricating composition is made in accordance with the guidelines of ISO 16128-2:2017 Cosmetics - Technical definitions and standards for natural and organic cosmetic ingredients, the contents of which are incorporated by reference.

[0092] In one embodiment, the natural content of the lubricating composition is calculated according to ISO16128-2:2017, the contents of which are incorporated by reference.

[0093] As used herein, unless otherwise defined, "Natural Index" is as defined by clause 4.3.1 of ISO 16128-2:2017, the contents of which are incorporated by reference.

[0094] The natural index is a value indicating the degree to which a cosmetic ingredient meets the definition of a natural ingredient from ISO16128-1:2016, clause 2. Unless otherwise defined, a value is assigned to each ingredient according to the following guidance: Natural Index = 1: The ingredient meets the definition of a natural ingredient. The natural index of the constituent water, reconstituted water, extracted water, and blended water are each considered to be equal to 1. ● Natural index = 0: The ingredient does not meet the definition of a natural ingredient.

[0095] The natural index of the extract was calculated according to formula (1):

number

[0096] In one embodiment, at least one component of the lubricating composition has a Natural Index of 1. In another embodiment, multiple components of the lubricating composition, for example, 2, 3, 4, 5, or more, have a Natural Index of 1.

[0097] As used herein, unless otherwise defined, the Index of Natural Origin is defined in Section 4.3 of ISO 16128-2:2017, the contents of which are incorporated by reference.

[0098] The natural origin index is a value indicating the degree to which a cosmetic ingredient meets the definition of either a natural ingredient in ISO 16128-1:2016, clause 2, a natural ingredient derived from ISO 16128-1:2016, clause 3, or a mineral ingredient derived from ISO 16128-1:2016, clause 4.

[0099] Values ​​are assigned to each component according to the following guidelines: Natural Origin Index = 1: The ingredient meets the definition of a natural ingredient, constituent water, reconstituted water, extracted water, or blended water. Extracts of natural ingredients using ingredient solvents that are natural or derived natural of entirely natural origin (according to ISO16128-1:2016, Table A.1) have a natural origin index of 1. 0.5<Natural Origin Index≦1: The ingredient meets the definition of a derived natural ingredient or a derived mineral ingredient. The value is calculated as the ratio of the natural origin portion to the total molecular composition of the ingredient, as determined by molecular weight, renewable carbon content, or any other relevant method. Natural Origin Index = 0: The ingredient does not meet the definition of a natural ingredient, nor the definition of a derived natural ingredient, nor the definition of a derived mineral ingredient and contains an ingredient that has been calculated to have a Natural Origin Index of 0.5 or less.

[0100] In one embodiment, at least one component of the lubricating composition has a natural origin index of 1. In another embodiment, multiple components of the lubricating composition, for example, 2, 3, 4, 5, or more, have a natural origin index of 1.

[0101] Natural origin content. In one embodiment, the natural origin content of the lubricating composition is about or at least about 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 99.1%, 99.2%, 99.3%, 99.4%, 99.5%, 99.6%, 99.7%, 99.8%, or 99.9%. In another embodiment, the natural origin content of the lubricating composition is in the range of about 95 to about 100%. In yet another embodiment, the natural origin content of the lubricating composition is greater than 99%.

[0102] In one embodiment, the lubricating composition is free of silicon or silicone-based compounds.

[0103] Grading of ingredients The components and / or excipients of the lubricating compositions described herein can be food grade (i.e., safe for food use), cosmetic grade, United States Pharmacopeia (USP) grade, British Pharmacopoeia (BP) grade, European Pharmacopoeia (Ph.Eur) grade, National Formulary (NF) grade, Japanese Pharmacopoeia (JP) grade, and / or Japanese Pharmaceutical Excipient (JPE) grade.

[0104] attribute In one embodiment, the lubricant composition is clear, substantially clear, or translucent.

[0105] In one embodiment, the lubricant composition is colorless or substantially colorless.

[0106] In another embodiment, the lubricant composition has at least one of the following attributes: transparent or substantially transparent; free or substantially free of foreign matter; free or substantially free of any contaminating or potentially contaminating materials.

[0107] In one embodiment, the lubricant composition is amenable to gynecological and / or dermatological applications, for example, the lubricant composition may comply with the internationally recognized guidelines of the International Contact Dermatitis Study Group.

[0108] In one or more embodiments, the lubricating composition may be formulated to be odorless or substantially odorless, and / or tasteless or substantially tasteless. Flavorless and / or fragrance-free lubricant compositions may be preferred by certain individuals and may result in a lubricating composition that is less allergenic and / or irritating to subjects with sensitive skin, for example.

[0109] In another embodiment, the lubricant composition is in compliance with the SCCS Notes of Guidance for the Testing of Cosmetic Ingredients and Their Safety Evaluation-11, adopted at its meeting on March 30-31, 2021. th Revision (SCCS / 1628 / 21), the contents of which are incorporated by reference.

[0110] In another embodiment, the lubricating composition is formulated for vaginal and / or penile use. In another embodiment, the lubricating composition is formulated for vaginal use. In yet another embodiment, the lubricating composition is formulated for penile use.

[0111] In one embodiment, the lubricating composition is free or substantially free of silicone-based lubricants or components. In another embodiment, the lubricating composition is free of silicone-based lubricants. In yet another embodiment, the lubricating composition is free of silicon-containing components.

[0112] In one embodiment, the lubricating composition comprises at least about 25.0%, 22.5%, 20.0%, 17.5%, 15.0%, 12.5%, 10.0%, 7.5%, 5.0%, 4.0%, 3.0%, 2.0%, 1.0%, 0.5%, or 0% or less of at least one of parabens (e.g., one or more of ethylparaben, butylparaben, isobutylparaben, isopropylparaben, methylparaben, and propylparaben), chlorophenesin, phenoxyethanol, glycerin, and / or propylene glycol. In another embodiment, the lubricating composition is free or substantially free of parabens. In another embodiment, the lubricating composition comprises less than 10% glycerin, is free or substantially free of glycerin. In yet another embodiment, the lubricating composition comprises less than 25% propylene glycol, is free or substantially free of propylene glycol.

[0113] The lubricating composition can be tailored depending on the desired application.

[0114] In one embodiment, the lubricating composition is formulated such that it can be applied to the skin of an individual, for example, by direct application (e.g., from a suitable container) or by one or more transfers (e.g., from skin-to-skin contact with another individual).

[0115] In one embodiment, the lubricating composition is formulated as a coating, for example, a coating for an article as defined herein.

[0116] In one embodiment, the lubricating composition is formulated to be suitable for application to an article, such as an article that comprises or consists of natural rubber latex or polyisoprene. In one embodiment, the article comprises or consists of natural rubber latex. In one embodiment, the article comprises or consists of polyisoprene.

[0117] pH As used herein, the pH range of the lubricating composition may be in the range of about 3.5 to about 5.5, such as about 3.8 to about 4.5. In one embodiment, the pH is about, at least about 3.5, or 3.6, or 3.7, or 3.8, or 3.9, or 4.0, or 4.1, or 4.2, or 4.3, or 4.4, or 4.5, or 4.6, or 4.7, or 4.8, or 4.9, or 5.0, or 5.1, or 5.2, or 5.3, or 5.4, or 5.5, or less.

[0118] The pH of the lubricating composition may be modified depending on the application and / or the article to which the lubricating composition is applied.

[0119] In some embodiments, the lubricating composition is effective as a vaginal lubricant and has a pH in the range of about 3.5 to about 5.5, e.g., less than about, or at least about, about 3.5, or 3.6, or 3.7, or 3.8, or 3.9, or 4.0, or 4.1, or 4.2, or 4.3, or 4.4, or 4.5, or 4.6, or 4.7, or 4.8, or 4.9, or 5.0, or 5.1, or 5.2, or 5.3, or 5.4, or 5.5.

[0120] In some embodiments, the lubricating composition is effective as a penile lubricant and has a pH in the range of about 3.5 to about 5.5, e.g., less than about, or at least about, about 3.5, or 3.6, or 3.7, or 3.8, or 3.9, or 4.0, or 4.1, or 4.2, or 4.3, or 4.4, or 4.5, or 4.6, or 4.7, or 4.8, or 4.9, or 5.0, or 5.1, or 5.2, or 5.3, or 5.4, or 5.5.

[0121] viscosity As used herein, the viscosity of the lubricating composition may be measured according to ASTM D2196-2020.

[0122] As used herein, viscosity is defined as the viscosity of the United States Pharmacopeia (USP) <912> , may be measured, for example, according to the rotational method using a Brookfield viscometer (DV2T LVT) at a test temperature, for example 25°C.

[0123] In one embodiment, the lubricating composition is a non-Newtonian fluid.

[0124] As used herein, the lubricating composition may have a viscosity in the range of about 10 to about 10,000 cP, such as in the range of about 1000 to about 5000 cps, or about 2200 to about 3500 cps. For example, a viscosity of about, or at least about, 10 cP, or 50 cP, or 100 cP, or 200 cP, or 300 cP, or 400 cP, or 500 cP, or 600 cP, or 700 cP, or 800 cP, or 900 cP, or 1000 cP, or 1500 cP, or 2000 cP, or 2500 cP, or 3000 cP, or 3500 cP, or 4000 cP, or 4500 cP, or 5000 cP, or 5500 cP, or 6000 cP, or 6500 cP, or 7000 cP, or 7500 cP, or 8000 cP, or 8500 cP, or 9000 cP, or 9500 cP, or 10000 cP.

[0125] The viscosity of the lubricating composition at 25° C. can be from about 1000 cps to about 10,000 cps, for example, a viscosity of about, or at least about: 1000 cP, or 1500 cP, or 2000 cP, or 2500 cP, or 3000 cP, or 3500 cP, or 4000 cP, or 4500 cP, or 5000 cP, or 5500 cP, or 6000 cP, or 6500 cP, or 7000 cP, or 7500 cP, or 8000 cP, or 8500 cP, or 9000 cP, or 9500 cP, or 10000 cP.

[0126] In the case of a vaginal lubricant, the viscosity of the lubricating composition may range from about 1000 cps to less than about 10,000 cps, such as from about 1000 to about 5000 cps, or from about 2200 to about 3500 cps, e.g., about, at least about 1000 cP, or 1500 cP, or 2000 cP, or 2500 cP, or 3000 cP, or 3500 cP, or 4000 cP, or 4500 cP, or 5000 cP, or 5500 cP, or 6000 cP, or 6500 cP, or 7000 cP, or 7500 cP, or 8000 cP, or 8500 cP, or 9000 cP, or 9500 cP, or 10000 cP, or less.

[0127] In one embodiment, the lubricating composition has a viscosity, e.g., a dynamic viscosity, of about, or less than about 250 cP, 500 cP, 750 cP, 1000 cP, 1250 cP, 1500 cP, 1750 cP, 2000 cP, 2500 cP, 3000 cP, 3500 cP, 4000 cP, 4500 cP, 5000 cP, 5500 cP, 6000 cP, 6500 cP, 7000 cP, 7500 cP, 8000 cP, 8500 cP, 9000 cP, 9500 cP, or 10000 cP.

[0128] Lubricity In one embodiment, the lubricating composition is characterized by its lubricity, which can be measured by the coefficient of friction.

[0129] In another embodiment, the lubricating composition is characterized by its long-lasting lubricity, where the composition provides adequate lubrication for an acceptable period of time, e.g., in relation to a particular application or use, e.g., while stored in a container and / or after exposure to the atmosphere (e.g., after being removed from a container or dispersed). The "long-lasting" attribute may allow for a longer duration of action of the lubricating composition and / or may allow for less frequent application of the lubricating composition (e.g., when used as a massage oil or during sexual intercourse).

[0130] In another embodiment, after exposure to the atmosphere and application to an article or body part, the lubricity of the lubricating composition is consistent or substantially consistent after at least 5 minutes, 10 minutes, 20 minutes, 30 minutes, 40 minutes, 50 minutes, 1 hour, 2 hours, 3 hours, 4 hours, or 5 hours after application to the surface of the article or body part.

[0131] In another embodiment, the lubricating composition can provide adequate lubricity after being stored for a period of, for example, about or at least about 1 week, 2 weeks, 3 weeks, 4 weeks, 1 month, 2 months, 3 months, 6 months, 12 months, 18 months, 24 months, 30 months, 36 months, 42 months, or 48 months for a particular use or application. The lubricating composition can be stored at a range of temperatures including about or at least about 0°C, 15°C, 20°C, 25°C, 30°C, or 40°C. In some embodiments, the lubricating composition can be shelf stable and will not physically degrade / spoil at room temperature for a period of about or at least about 1 month, 2 months, 3 months, 4 months, 5 months, 6 months, 7 months, 8 months, 9 months, 10 months, 11 months, 1 year, 1.5 years, 2 years, 2.5 years, or 3 years. In yet another embodiment, the lubricating composition can be shelf stable for at least 3 years. In one embodiment, the lubricating composition has sufficient stability over a period of time to resist changes in its physicochemical properties. Such changes may include changes in color, clarity, and / or odor over a given time. In other embodiments, the lubricating composition has sufficient stability over a period of time to be free or substantially free of unacceptable changes in parameters such as pH, viscosity, performance, and / or other measurable product specifications.

[0132] In one embodiment, the lubricating composition has long lasting lubricity for about, or at least about, 100 rounds, 200 rounds, 300 rounds, 400 rounds, 500 rounds, 600 rounds, 700 rounds, 800 rounds, 900 rounds, 1000 rounds, 1100 rounds, 1200 rounds, 1300 rounds, 1400 rounds, 1500 rounds, or 1600 rounds.

[0133] In one embodiment, lubricity is measured via a method including: a) measuring an amount of a sample of the lubricant composition, e.g., 0.1 g, and spreading the same amount on the back of the subject's hand (in one embodiment, all measured amounts are applied to the same hand); b) spreading the lubricant composition on one's hand and measuring the number of times and the time it takes for the lubricant composition to dry; c) Once all the lubricant has dried, wash your hands (e.g., with soap) and dry them. d) Repeat the test, for example, two more times.

[0134] Osmolality concentration As used herein, the osmolality of the lubricating composition is determined according to the United States Pharmacopoeia (USP) Osmolality. <785> It can be measured according to

[0135] In one embodiment, the osmolality of the lubricating composition can be in the range of about 2500 mOsm / kg to about 4500 mOsm / kg, for example, in the range of about 3100 to about 4100 mOsm / kg. For example, the osmolality can be 4500 mOsm / kg, or 4400 mOsm / kg, or 4300 mOsm / kg, or 4200 mOsm / kg, or 4100 mOsm / kg, or 4000 mOsm / kg, or 3900 mOsm / kg, or 3800 mOsm / kg, or 3700 mOsm / kg, or 3600 mOsm / kg, or 3500 mOsm / kg, or 3400 mOsm / kg. The blood glucose level may be, about, greater than, or less than 3300 mOsm / kg, or 3200 mOsm / kg, or 3100 mOsm / kg, or 3000 mOsm / kg, or 2900 mOsm / kg, or 2800 mOsm / kg, or 2700 mOsm / kg, or 2600 mOsm / kg, or 2500 mOsm / kg.

[0136] Microbiological Testing As used herein, the lubricant composition may be formulated such that it complies with relevant microbial testing. For example, the lubricant composition may be formulated to comply with the United States Pharmacopoeia (USP) <51> , <61> and <62> The measurement may be performed according to at least one of the following:

[0137] In one embodiment, the lubricant composition does not allow or reduces the growth of at least one of microorganisms, molds, and / or yeasts.

[0138] In one embodiment, the U.S.P. <61> The total aerobic microbial count (TAMC) according to is about 100, or 90, or 80, or 70, or 60, or 50 cfu / g.

[0139] In another embodiment, the U.S.P. <61> The total yeast / mold count (TYMC) by ELISA is approximately 10 cfu / g.

[0140] In another embodiment, the Antimicrobial Effectiveness Test (AET) is used to determine the USP <51> and for bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus, there is a 2.0 log or greater reduction from the initial count on day 14, and no increase from the count on day 14 on day 28, and for yeasts and molds such as Aspergillus brasiliensis and Candida albicans, there is no increase from the initial calculated count on days 14 and 28.

[0141] In yet another embodiment, the U.S.P. <62> According to the present invention, one or more of the following microorganisms are not present or absent in the lubricating composition: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Salmonella spp, Clostridium spp, and / or Candida albicans. In yet another embodiment, none of the following microorganisms are present in the lubricating composition: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Salmonella spp, Clostridium spp, and Candida albicans.

[0142] Articles and uses Disclosed herein are articles comprising the personal aqueous lubricating compositions defined herein.

[0143] Also referred to herein is a coating comprising the personal aqueous lubricating composition as defined herein.

[0144] Also disclosed is the use of the lubricating composition as defined herein. In one embodiment, the lubricating composition is used as a coating. In another embodiment, the lubricating composition is used as a lubricant, and the lubricant composition is optionally applied directly to at least a portion of the skin of an individual.

[0145] In one embodiment, the lubricating composition is formulated and / or used as a massage gel or liquid.

[0146] The lubricating composition may be used in one or more intimate care applications, for example as a personal lubricant involving one or more body parts, for example, private body parts where such compositions are placed and / or used during sexual activity. In one embodiment, the lubricant composition is effective as a lubricant and useful in intimate care applications. In another embodiment, the lubricating composition is substantially non-irritating to body parts, for example, private human body parts, such as the skin and at least one of the oral, anal, penile, and vaginal mucosa, particularly during sexual activity.

[0147] In one embodiment, the lubricating composition is disposed on a portion, substantially all, or all of at least one surface of the article. Reference to "at least one surface" may be the exterior and / or interior surface of the article.

[0148] The lubricating composition may be disposed on at least a portion of the article in a process including or consisting of one or more of spraying, dipping, sponging, rolling in the lubricant composition, dosing, or mixtures thereof.

[0149] The lubricating composition may be in the form of a coating on at least a portion of the article. For example, the lubricating composition may be applied to at least about 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, or 95% of the article. Further, the lubricating composition may be applied to at least about 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, or 95% of at least one surface of the article. In one embodiment, at least a portion of at least one exterior surface comprises a lubricating composition as defined herein.

[0150] The article may be in the form of, or part of, a contraceptive device.

[0151] The article may be in the form of, or part of, a sex toy.

[0152] In one embodiment, the article may be selected from a condom, a cervical cap, a coil, a contraceptive diaphragm, a diaphragm, an intrauterine device (IUD), a sex toy, or a spermicide.

[0153] The article may be in the form of a condom, for example, with the lubricating composition covering a portion of it or covering substantially the entire length of the condom, packaged or unpackaged. In one embodiment, the lubricating composition is disposed on a portion, substantially, or all of one or all of the outer surfaces of the condom. The condom may comprise, consist essentially of, or consist of an elastomeric material (such as natural latex rubber), a synthetic material (such as a polyisoprene material, a polymer blend, or a similar polymeric material). In another embodiment, the condom comprises or consists of a material selected from, but not limited to, natural rubber latex or polyisoprene. In one embodiment, the condom comprises, consists essentially of, or consists of natural rubber latex. In one embodiment, the condom comprises, consists essentially of, or consists of polyisoprene.

[0154] As used herein, compatibility of a lubricating composition with a condom can be measured by ASTM D7661-18 Standard Test Method for Determining Personal Lubricants with Natural Rubber Latex Condoms, and / or ISO19671:2018 Additional lubricants for male natural rubber latex condoms-Effect on condom strength.

[0155] As used herein, the term "natural rubber latex" encompasses cured elastomeric materials sourced from Hevea brasiliensis (the traditional rubber tree), non-Hevea rubbers such as Parthenium argentatum (guayule), sunflower, goldenrod, and genetically modified variations of these or other biological sources. In some embodiments of the invention, condoms comprise pre-vulcanized and post-vulcanized latex compositions.

[0156] In one embodiment, the article is a condom. In addition to the lubricating composition, the condom may further comprise one or more additional components, such as, but not limited to, flavors, fragrances, active ingredients, and / or mixtures thereof. Examples of active ingredients include one or more of the following: pharmaceuticals (such as one or more of antiviral, antibacterial, and / or antifungal agents), vasodilators (such as niacin, sildenafil citrate, and / or nitroglycerin), male desensitizers (such as benzocaine), warming or cooling liquids (such as caffeine or menthol), and spermicides (such as nonoxynol-9).

[0157] The articles may comprise the lubricating composition in an amount of at least about 50 mg, 100 mg, 150 mg, 200 mg, 250 mg, 300 mg, 350 mg, 400 mg, 450 mg, 500 mg, 550 mg, 600 mg, 650 mg, 700 mg, 750 mg, 800 mg, 850 mg, 900 mg, 950 mg, or 1000 mg per article.

[0158] Synthesis method Disclosed herein is a method for preparing a lubricating composition as defined herein.

[0159] In one exemplary, non-limiting method, the lubricating composition was synthesized using one or more of the following steps: a) Weigh or measure deionized water (DI water) into a first container, optionally under stirring. b) Sodium lactate and / or benzoic acid and / or sorbic acid and / or potassium sorbate are added to the DI water and stirred for a period of time, for example about 5 minutes. c) In a second container, pre-disperse flaxseed gum and hydroxyethylcellulose and / or xanthan gum and / or hyaluronic acid and / or sclerotium gum in 1,3-propanediol. Stir for a period of time, for example about 5 minutes, or until the contents are well dispersed. d) The dispersion from the second container is added to the first container and stirring is continued for a period of time, for example about 10 minutes. e) Add okra gel and / or aloe vera extract to the first container and stir for a period of time, for example 5 minutes.

[0160] Exemplary embodiments 1. A personal aqueous lubricating composition comprising at least one of a part or extract from an okra plant species and a part or extract from a flaxseed plant species, wherein the extract from the flaxseed plant species is optionally a gum. 2. The composition of exemplary embodiment 1, wherein the composition comprises at least one part or extract from an Okra plant species. 3. The composition of any one of the preceding exemplary embodiments, wherein the composition comprises at least one part or extract from a flaxseed plant species. 4. The composition of any one of the preceding exemplary embodiments, wherein the composition comprises at least one part or extract from an okra plant species and a flaxseed plant species. 5. The composition of any one of the preceding exemplary embodiments, wherein the okra plant species belongs to the genus Abemoschus. 6. The composition of any one of the preceding exemplary embodiments, wherein the okra plant species is selected from one or more of Abelmoschus esculentus, Abelmoschus caillei, Abelmoschus manihot, Abelmoschus ficuneus, Abelmoschus moschatus, or any mixture of two or more species thereof. 7. The composition of any one of the preceding exemplary embodiments, wherein the flaxseed plant species belongs to the genus Linum. 8. The composition of any one of the preceding exemplary embodiments, wherein the flaxseed plant species is selected from one or more of Linum usitatissimum, Linum humile, Linum austriacum, Linum bienne, Linum angustifolium, Linum catharticum, Linum flavum, Linum grandiflorum, Adenolinum grandiflorum, Linum lewisii, Linum narbonense, Linum perenne, Linurn perenne var. lewisii, Linum pratense, and Linum trigynum, or any mixture of two or more species thereof. 9. Each extract or portion thereof independently has a concentration of about, or at least about, 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2 ... The composition of any one of the preceding exemplary embodiments, wherein the composition is present in an amount of 1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, 3.0, 3.1, 3.2, 3.3, 3.4, 3.5, 3.6, 3.7, 3.8, 3.9, 4.0, 4.1, 4.2, 4.3, 4.4, 4.5, 4.6, 4.7, 4.8, 4.9, or 5.0% w / w. 10. The composition of any one of the preceding exemplary embodiments, wherein the extract or a portion thereof is provided in the form of a liquid, oil, gel, powder, granules, or a mixture thereof. 11. The composition of any one of the preceding exemplary embodiments, wherein the composition further comprises at least one additional component or excipient that is a natural ingredient. 12. The composition of any one of the preceding exemplary embodiments, wherein the composition further comprises at least one additional component or excipient which is a natural ingredient that is an extract from a plant or a portion thereof. 13. The composition of any one of the preceding exemplary embodiments, wherein the composition optionally further comprises at least one additional component or excipient which is a natural ingredient selected from a botanical or plant source, a seaweed source, and / or a natural gum produced by bacterial fermentation. 14. The composition of any one of exemplary embodiments 11-13, wherein at least one natural ingredient is provided in the form of a liquid, oil, gel, powder, or granules. 15. At least one natural ingredient is at least about 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, 0.08, 0.09, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, 3.0, 3.1, 3.2, 3.3, 3.4, 3.5, 3.6, 3.7, 3.8, 3.9 ...7, 3.8, 3.9, 3.1, 3.2, 3.3, 3.4, 3.5, 3.8, 3.9, 3.1, 3.1, 3.2, 3.3, 3.4, 3.5, 3.1, 3.2, 3.3, 3.4, 3.5, 3.6, 3.7, 3.8, 3.9, 3.1, 3.2, 3.3, 3.4, 3.5, 3.8, 3.9, 3.1, 3.1, 3.2, 3.3 15. The composition of any one of exemplary embodiments 11-14, wherein the soluble ... 16. The composition of any one of the preceding exemplary embodiments, wherein the composition is a non-Newtonian fluid. 17. The composition of any one of the preceding exemplary embodiments, comprising at least one component which is a humectant, emollient, preservative, thickener, perfume / fragrance, pH adjuster, pH buffer, emulsifier, surfactant, emollient, cooling agent and / or tingling agent, or a mixture thereof. 18. The composition comprises about, or at least about, 40, 42, 44, 46, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, or 96% w / w, or 40%, 42, 44, 46, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, The composition of any one of the preceding exemplary embodiments, comprising or consisting of 80, 82, 84, 86, 88, 90, 92, 94, or 96% w / v, or 40%, 42, 44, 46, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, or 96% v / v water. 19. The composition of any one of the preceding exemplary embodiments, wherein the lubricating composition is optionally free or substantially free of parabens selected from ethylparaben, butylparaben, isobutylparaben, isopropylparaben, methylparaben, and / or propylparaben. 20. The composition of any one of the preceding exemplary embodiments, wherein the composition comprises or consists of about, or at least about, 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, 99.1%, 99.2%, 99.3%, 99.4%, 99.5%, 99.6%, 99.7%, 99.8%, or 99.9% natural origin content as measured according to ISO 16128-2:2017. 21. The composition of any one of the preceding exemplary embodiments, wherein the composition is transparent, substantially transparent, or translucent. 22. The composition of any one of the preceding exemplary embodiments, wherein the lubricating composition has one or more of the following characteristics, optionally measured at 25° C.: a pH in the range of about 3.5 to about 5.5, or about 3.8 to about 4.5; an osmolality in the range of about 2500 mOsm / kg to about 4500 mOsm / kg, or about 3100 to about 4100 mOsm / kg; and / or a viscosity in the range of about 1000 to about 5000 cps, or about 2200 to about 3500 cps. 23. The composition of any one of the preceding exemplary embodiments, wherein the composition is formulated for application to the penis and / or vagina. 24. The composition of any one of the preceding exemplary embodiments, wherein the composition is formulated for vaginal use. 25. The composition of any one of the preceding exemplary embodiments, wherein the composition is formulated for application to the skin of an individual. 26. The composition of any one of the preceding exemplary embodiments, wherein the composition is compatible with an article comprising or consisting of natural rubber latex. 27. The composition of any one of exemplary embodiments 1-25, wherein the composition is compatible with an article comprising or consisting of polyisoprene. 28. The composition of any one of the preceding exemplary embodiments, wherein the article is a contraceptive device, optionally a condom. 29. The composition of any one of the preceding exemplary embodiments, wherein the lubricity of the composition is consistent or substantially consistent after about, or at least about, 10 minutes, 15 minutes, 20 minutes, 25 minutes, 30 minutes, 35 minutes, 40 minutes, 45 minutes, 50 minutes, 55 minutes, 1 hour, 2 hours, 3 hours, 4 hours, or 5 hours after application to the surface of the article or body part. 30. The composition of any one of the preceding exemplary embodiments, wherein the lubricating properties of the lubricating composition are consistent or substantially consistent with a silicone-based lubricating composition comprising siloxane and / or cyclomethicone. 31. A massage gel or liquid comprising a personal aqueous lubricating composition according to any one of exemplary embodiments 1-30. 32. A coating comprising a personal aqueous lubricating composition according to any one of exemplary embodiments 1-30. 33. An article comprising the personal aqueous lubricating composition of any one of exemplary embodiments 1-30 or the coating of exemplary embodiment 32. 34. The article of exemplary embodiment 33, wherein the article is a contraceptive device. 35. The article of exemplary embodiment 33 or 34, wherein the article is selected from a condom, a cervical cap, a coil, a contraceptive diaphragm, a pessary, an intrauterine device (IUD), a sex toy, or a spermicide. 36. The article of any one of exemplary embodiments 33-35, wherein the article is a condom. 37. Use of a personal aqueous lubricating composition according to any one of exemplary embodiments 1 to 30 as a massage gel or liquid. 38. Use of a personal aqueous lubricating composition according to any one of exemplary embodiments 1 to 30 as a coating. 39. The use of exemplary embodiment 38, wherein the coating is for an article of any one of exemplary embodiments 33 to 35. 40. Use of a personal aqueous lubricating composition according to any one of exemplary embodiments 1 to 30 as a lubricant, wherein the lubricant composition is optionally applied directly to at least a portion of an individual's skin. EXAMPLES

[0161] The present disclosure will now be described with reference to the following non-limiting examples, and with reference to the accompanying drawings (where applicable).

[0162] Example 1 - Example Composition A series of exemplary compositions were prepared using the general approach described in paragraph

[0142] and shown in Table 1. These example compositions likely provide similar lubricity compared to commercially available silicone-based personal lubricants available on the market. [Table 1]

[0163] For the compositions in Table 1, the material selection was made according to the guidelines of ISO16128:2016 Cosmetics - Technical definitions and standards for natural and organic cosmetic ingredients (both the natural index and the natural origin index can be calculated according to ISO16128-2:2017. For example, two different compositions of Formula H can result in a natural origin content of 99.53 and 100.

[0164] The lubricity properties of the composition of Formula H were tested. The results are shown in Table 2. Additional characteristics of this exemplary formula are also disclosed in Table 2.

[0165] The following method was used to test the lubricity. a. Measure out 0.1 g of lubricant and spread the same amount on the back of your left hand. Ensure that the entire measured amount is applied to your hand. b. The lubricant is spread on the left hand and the number of rounds and time it takes for the lubricant to dry are measured. c. Once all the lubricant has dried, wash your hands with soap and towel dry. d. Repeat the test two more times. [Table 2]

[0166] A sample of Formula H was also examined after aging for one month at 50°C. Initial appearance, viscosity, and pH were compared to the same characteristics after aging. The results are shown in Table 3. The viscosity characterization of two different variations of Formula H (Formula 1 and Formula 2) is shown in Figure 1. [Table 3]

[0167] Furthermore, the compositions in Table 1 are also <51> , <61> , and <62> The exemplary lubricants above passed microbial testing according to the following specifications: Total aerobic microbial count <100cfu / g Total mold and yeast <10 cfu / g (Category 2 products) <51> (Measured according to Absence of the following microorganisms: -Staphylococcus aureus -Pseudomonas aeruginosa -Escherichia coli -Salmonella sp. -Clostridium sp. -Candida albicans

[0168] Example 2 - Coefficient of friction (COF) test Tribological testing of three lubricants (silicone gel, natural personal lubricant (NPL), and OFNat) and water was performed to compare their ability to maintain COF during a 45-minute test (to simulate sexual activity) and to examine changes in this characteristic over time.

[0169] Lubricant NPL contains xanthan gum, sodium hyaluronate, glycerin, sodium chloride, sorbic acid, potassium sorbate and water. Lubricant OFNat is within the composition H of Table 1.

[0170] method The method used was R&D.TM.10: Determination of the Coefficient of Friction. During the tribological test, the slope of the increased COF is determined, which is calculated from the start to the end of the 45 minute (maximum intercourse duration) tribological test. Three balls on a plate geometry move in a circular motion on a silicone gel pad substrate lubricated with a lubricant sample. The increase in COF over time represents the rate at which lubrication is lost.

[0171] result The four tested samples (water, NPL, silicone gel, and OFNat) were applied to a silicone pad to determine the lubricity of a 45 minute tribological test. All samples except water were able to maintain a COF of 0.2 for the entire test period of about 45 minutes.

[0172] The COF of OFNat was lower than NPL during the test, indicating better lubricity. The COF of NPL started to fluctuate at about 1500 seconds, meaning that the lubricant started to lose its lubricity, while the COF of OFNat started to fluctuate at about 2300 seconds, indicating that it can maintain lubricity for a longer period than NPL. Furthermore, the COF of OFNat was close to the silicone gel benchmark (see Figure 2) due to its well-known lubricity.

[0173] The area under the curve for each tribological test sample was calculated by Rheology Trios software. The results are shown in Table 4 and a comparison is shown in Figure 3, images A) and B). For Figure 3, image A), equal variances were assumed for the analysis. For Figure 3, image B), the pooled standard deviation is used to calculate the intervals. Figure 3: The null hypothesis is that all means are equal, the alternative hypothesis is that all means are not equal, the significance level is α = 0.05. The analysis of variance is shown in Table 5. [Table 4] [Table 5]

[0174] The overall COF as well as the area under the curve (371.617-499.391) of OFNat lubricant is close to the results of the silicone gel and is significantly lower than the NPL lubricant during the COF test. Therefore, it can be concluded that OFNat lubricant provides better lubrication than the NPL lubricant and therefore provides a long-lasting lubricating composition.

[0175] Example 3 - Adhesion Test the purpose Adhesion tests of four lubricants and water were conducted to compare the retraction force between the two plates at a temperature of 37° C. to simulate a suitable environment and emulate the human body.

[0176] method The method used is R&D.TM.11: Determination of Stickiness. The stickiness of a composition (e.g. lubricant) was determined by the retraction force between two plates lubricated with the composition. The higher the retraction force (absolute value), the higher the stickiness.

[0177] result Five different samples (water, aqueous lubricant A-control, silicone gel, NPL, and OFNat) were applied between the two plates and then pulled to determine the retraction force. All samples show consistent results over 13 replicates. An overlay of the averages from the 13 replicates for each sample is shown in FIG. 4.

[0178] Water-based lubricant A was used as a benchmark and positive control based on consumer feedback related to stickiness. The results show that water-based lubricant A required the most force to pull up the top plate, as can be seen from the high absolute value of the axial force at the beginning of the retraction step shown in Figure 4. Silicone gel showed very low retraction force, as did water (negative control). OFNat and NPL water-based lubricants showed similar retraction force values ​​and much lower retraction force as water-based lubricant A (Table 6 and Figures 4 and 5). In Figure 5, the null hypothesis is that all means are equal, the alternative hypothesis is that all means are not equal, and the significance level is α=0.05. The analysis of variance is shown in Table 7. [Table 6] [Table 7]

[0179] The retraction force of OFNat was lower and significantly different than that of water-based lubricant A. It can be concluded that the OFNat water-based lubricant offers a means of circumventing the problems associated with adhesive properties and was found to be less adhesive compared to the water-based lubricant A tested.

[0180] Example 4 - Fabric dyeing and cleaning test the purpose To carry out fabric dyeing studies of OFNat lubricants using in-house adapted methods.

[0181] method The method used was R&D001-21-P6. The main part of the test was to carry out a fabric dye test on selected fabrics, where a certain amount of OFNat lubricant was applied, and then the fabric was washed. The test results were compared to the same fabrics (control) without OFNat lubricant applied. In addition, a non-water-based lubricant (silicone gel lubricant) was also tested to evaluate the ease and effectiveness of washing compared to OFNat lubricant.

[0182] result: The results showed that OFNat lubricant left no visible traces on polyester, cotton, satin, and synthetic silk fabrics after hanging to dry. The washing conditions are listed in Table 8 and the results are shown in Table 9. After washing and drying, the fabrics (polyester, cotton, satin, synthetic silk) retained a stained trace of the silicone gel lubricant. These results highlight that OFNat lubricant does not stain and washes off easily from a variety of different fabrics. [Table 8] [Table 9]

[0183] Example 5 - Condom compatibility test the purpose OFNat lubricants are tested for condom compatibility with three different commercial brands of natural rubber latex (NRL) condoms (A, B, C) and three different commercial lots of synthetic polyisoprene (PI) condoms (D1, D2, D3) (Table 10).

[0184] method Testing was performed in accordance with ASTM D7661-18.

[0185] The essence of the study was to perform standard strength tests (tensile and burst strength tests) on selected condoms that had been treated with OFNat lubricant. These test results were compared to those generated with condoms from the same population (control samples) that had not been treated with OFNat lubricant. [Table 10]

[0186] All samples were tested at the Research, Development and Innovation Center in Surat Thani, Thailand.

[0187] result: From the results in Table 11, the percent change in airburst volume, airburst pressure, breaking force, and elongation of treated and untreated condoms is within ±20%. Therefore, OFNat lubricant is compatible with NRL condoms.

[0188] From the results in Table 12, the percent change in airburst volume, airburst pressure, breaking force, and elongation of treated and untreated condoms is within ±20%. Therefore, OFNat lubricant is compatible with PI SKYN condoms.

[0189] Therefore, it can be concluded that OFNat lubricant is compatible with both natural rubber latex and polyisoprene condoms. [Table 11] [Table 12]

[0190] It will be understood by those skilled in the art that numerous variations and / or modifications may be made to the above-described embodiments without departing from the broad general scope of the present disclosure, and the present embodiments are therefore to be considered in all respects as illustrative and not restrictive.

Claims

1. A personal aqueous lubricating composition comprising at least a part or an extract from an okra plant species.

2. The composition according to claim 1, wherein the composition is a non-Newtonian fluid.

3. The composition according to claim 1, further comprising at least one part or an extract from a flaxseed plant species.

4. The composition according to claim 1, wherein the okra plant species is selected from one or more of Abelmoschus esculentus, Abelmoschus caillei, Abelmoschus manihot, Abelmoschus ficuneus, Abelmoschus moschatus, or a mixture of any two or more of these species.

5. The composition according to claim 3, wherein the flaxseed plant species is selected from one or more of Linum usitatissimum, Linum humile, Linum austriacum, Linum bienne, Linum angustifolium, Linum catharticum, Linum flavum, Linum grandiflorum, Adenolinum grandiflorum, Linum lewisii, Linum narbonense, Linum perenne, Linurn perenne var. lewisii, Linum pratense, and Linum trigynum, or a mixture of any two or more of these species.

6. The composition according to claim 3, wherein the flaxseed plant species is Linum usitatissimum.

7. The composition according to claim 1, wherein the extract or a part thereof is present in an amount of at least about 0.1% w / w.

8. The composition according to claim 1, wherein the extract or a part thereof is provided in the form of a liquid, oil, gel, powder, or granule, or a mixture thereof.

9. The composition according to claim 1, further comprising at least one additional constituent or excipient that is a natural ingredient.

10. The composition according to claim 1, further comprising at least one additional constituent or excipient that is a natural ingredient which is an extract from a plant or a part thereof. **Claim 11**: The composition according to claim 10, wherein the at least one further constituent or the natural constituent of the excipient is a natural gum selected from botanical or plant sources, or seaweed sources, or a natural gum produced by bacterial fermentation. **Claim 12** The composition according to claim 9, wherein at least one natural constituent is provided in the form of a liquid, an oil, a gel, a powder, granules, or a mixture thereof. **Claim 13** The composition according to claim 9, wherein the at least one natural constituent is present in an amount of at least about 0.1% w / w. **Claim 14** The composition according to claim 1, comprising at least one constituent that is a humectant, a skin softener, a preservative, a thickener, a fragrance / flavor, a pH adjuster, a pH buffer, an emulsifier, a surfactant, a softener, a cooling agent, a tingling agent, or a mixture thereof. **Claim 15** The composition according to claim 1, wherein the composition comprises or consists of at least about 40% w / w water. **Claim 16** The composition according to claim 1, wherein the lubricating composition does not contain or is substantially free of parabens selected from ethylparaben, butylparaben, isobutylparaben, isopropylparaben, methylparaben, propylparaben, or mixtures thereof. **Claim 17** The composition according to claim 1, wherein the composition comprises or consists of a natural origin content of at least about 95% when measured according to ISO 16128-2:2017. **Claim 18** The composition according to claim 1, wherein the composition is colorless, substantially transparent, and / or translucent. **Claim 19** The composition according to claim 1, wherein the lubricating composition has a pH in the range of about 3.5 to about 5.5, or about 3.8 to about 4.

5. **Claim 20** The composition according to any one of claims 1 to 19, wherein the lubricating composition has an osmotic concentration in the range of about 2500 mOsm / kg to about 4500 mOsm / kg, or about 3100 to about 4100 mOsm / kg. **Claim 21** The composition according to any one of claims 1 to 20, wherein the lubricating composition has a viscosity in the range of about 1000 to about 5000 cps, or about 2200 to about 3500 cps when measured at 25°C. **Claim 22** The composition according to claim 1, wherein the composition is formulated for application to the penis, vagina, or a combination thereof. **Claim 23** The composition according to claim 1, formulated for vaginal use.

24. The composition according to claim 1, formulated for application to an individual's skin.

25. The composition according to claim 1, which is compatible with articles containing natural rubber latex or polyisoprene.

26. The composition according to claim 1, wherein the article is a contraceptive device or a condom.

27. The lubricity of the lubricating composition is consistent or substantially consistent at least about 10 minutes, 20 minutes, 30 minutes, 40 minutes, 50 minutes, 1 hour, 2 hours, 3 hours, 4 hours, or 5 hours after application to the surface of an article or body part, the composition according to claim 1.

28. The composition according to claim 1, wherein the area of the coefficient of friction of the lubricant over a period of about 45 minutes results in an average area in the range of about 350 to about 500.

29. The lubricity of the lubricating composition is consistent or substantially consistent with a silicone-based lubricating composition containing a siloxane, cyclomethicone, or a mixture thereof, the composition according to claim 1.

30. A massage gel or liquid comprising the personal aqueous lubricating composition according to claim 1.

31. A coating comprising the personal aqueous lubricating composition according to claim 1.

32. An article comprising the personal aqueous lubricating composition according to claim 1, or A coating comprising the personal aqueous lubricating composition according to claim 1.

33. The article according to claim 32, wherein the article is a contraceptive device.

34. The article according to claim 32, wherein the article is selected from a condom, a cervical cap, a coil, a contraceptive diaphragm, a pessary, an intrauterine device (IUD), a sex toy, or a spermicide.

35. The article according to claim 32, wherein the article is a condom.

36. Use of the personal aqueous lubricating composition according to claim 1 as a massage gel or liquid.

37. Use of the personal aqueous lubricating composition according to claim 1 as a coating.

38. Use of the personal aqueous lubricating composition according to claim 1 as a lubricant, wherein the lubricant composition is directly adhered to at least a portion of an individual's skin.

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