X-ray diagnostic apparatus, medical image processing apparatus, and medical image processing program
Patent Information
- Application Number
- JP2023129045
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2023-08-08
- Publication Date
- 2025-02-21
Smart Images
Figure 2025024784000001_ABST
Abstract
Description
[Technical field]
[0001] The embodiments disclosed in this specification and the drawings relate to an X-ray diagnostic apparatus, a medical image processing apparatus, and a medical image processing program. [Background technology]
[0002] When performing tomosynthesis imaging, the X-ray diagnostic apparatus first collects a plurality of projection data while changing the irradiation angle of the X-rays with respect to the subject. Next, the X-ray diagnostic apparatus generates a three-dimensional image (volume data) from the collected plurality of projection data. The plurality of slices included in the volume data are also referred to as tomographic images or tomosynthesis images. Here, a user such as a doctor can sequentially read the plurality of slices included in the volume data to check the presence or absence of a lesion and its condition.
[0003] Furthermore, a technology is known for generating a two-dimensional image that reflects information in a three-dimensional space that is the subject of tomosynthesis imaging. Such a two-dimensional image may be called a synthetic 2D image or a virtual projection image. A user such as a doctor can easily check the overall condition of a subject by interpreting the two-dimensional image. However, in a two-dimensional image, it is difficult to visually identify a lesion compared to when multiple slices are interpreted sequentially, and depending on the conditions for generating the two-dimensional image, some information contained in multiple slices may be missing. [Prior art documents] [Patent documents]
[0004] [Patent Document 1] Special Publication No. 2015-515296 Summary of the Invention [Problem to be solved by the invention]
[0005] One of the problems to be solved by the embodiments disclosed in this specification and the drawings is to support image diagnosis using tomosynthesis imaging. However, the problems to be solved by the embodiments disclosed in this specification and the drawings are not limited to the above problem. Problems corresponding to the effects of each configuration shown in the embodiments described below can also be positioned as other problems. [Means for solving the problem]
[0006] An X-ray diagnostic apparatus according to an embodiment includes an acquisition unit that acquires a plurality of projection data by performing tomosynthesis imaging of a subject, an image generation unit that generates a first plurality of slices based on the plurality of projection data, a display control unit that causes a display unit to display any one of the first plurality of slices as a slice to be displayed, and a reception unit that receives a designation of a position on the slice to be displayed, wherein the image generation unit generates a two-dimensional image based on the first plurality of slices, a second plurality of slices generated from the plurality of projection data under conditions different from those of the first plurality of slices, or the plurality of projection data, and the display control unit causes a portion of the two-dimensional image including a position corresponding to the position for which the designation was accepted to be superimposed near the position for which the designation was accepted on the slice to be displayed. [Brief description of the drawings]
[0007] [Figure 1] FIG. 1 is a block diagram showing an example of the configuration of an X-ray diagnostic apparatus according to the first embodiment. [Figure 2A] FIG. 2A is a diagram for explaining tomosynthesis imaging according to the first embodiment. [Figure 2B] FIG. 2B is a diagram for explaining tomosynthesis imaging according to the first embodiment. [Figure 2C] FIG. 2C is a diagram for explaining tomosynthesis imaging according to the first embodiment. [Diagram 3] FIG. 3 is a diagram for explaining the reconstruction of volume data according to the first embodiment. [Figure 4]FIG. 4 is a diagram showing an example of a plurality of slices and a two-dimensional image according to the first embodiment. [Diagram 5] FIG. 5 is a diagram showing a display example of a two-dimensional image according to the first embodiment. [Figure 6] FIG. 6 is a flowchart for explaining a series of processing steps of the X-ray diagnostic apparatus according to the first embodiment. [Figure 7] FIG. 7 is a block diagram showing an example of the configuration of a medical image processing system according to the second embodiment. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
[0008] Hereinafter, embodiments of an X-ray diagnostic apparatus, a medical image processing apparatus, and a medical image processing program will be described in detail with reference to the accompanying drawings.
[0009] (First embodiment) In the first embodiment, an X-ray diagnostic apparatus 10 shown in Fig. 1 will be described as an example. The X-ray diagnostic apparatus 10 is an apparatus that performs tomosynthesis imaging of a subject to collect projection data. Note that Fig. 1 will describe a case where the X-ray diagnostic apparatus 10 is a mammography apparatus as an example. In this case, the subject that is the subject to be imaged by the X-ray diagnostic apparatus 10 is, for example, a breast P of a patient.
[0010] 1 includes a base 101 and a stand 102. The stand 102 is erected on the base 101 and supports an imaging table 103, a compression plate 104, an X-ray tube 105, an X-ray aperture 106, an X-ray detector 107, and a signal processing circuit 108. Here, the stand 102 supports the imaging table 103, the compression plate 104, the X-ray detector 107, and the signal processing circuit 108 so as to be movable in the vertical direction.
[0011] The imaging table 103 is a table that supports the breast P, and has a support surface on which the breast P is placed. The compression plate 104 is disposed above the imaging table 103, and is provided so as to face the imaging table 103 in parallel. Here, the compression plate 104 is provided so as to be movable in a direction toward and away from the imaging table 103. For example, the compression plate 104 compresses the breast P supported on the imaging table 103 by moving in a direction approaching the imaging table 103. The breast compressed by the compression plate 104 is spread thinly, and the overlap of the mammary glands within the breast is reduced.
[0012] The X-ray tube 105 is a vacuum tube having a cathode (filament) that generates thermoelectrons and an anode (target) that generates X-rays upon impact of the thermoelectrons. The X-ray tube 105 generates X-rays by irradiating thermoelectrons from the cathode to the anode using a high voltage supplied from an X-ray high voltage device 111. Here, the X-ray tube 105 is configured to be movable so as to change the irradiation angle of X-rays to the breast P. The movement of the X-ray tube 105 will be described later.
[0013] The X-ray aperture 106 is disposed between the X-ray tube 105 and the compression plate 104, and controls the X-rays generated by the X-ray tube 105. For example, the X-ray aperture 106 has a collimator that narrows the irradiation range of the X-rays, and a filter that adjusts the X-rays.
[0014] The collimator in the X-ray aperture 106 has, for example, four slidable aperture blades, and by sliding these aperture blades, the X-rays generated by the X-ray tube 105 are narrowed down and irradiated onto the breast P. Here, the aperture blades are plate-shaped members made of lead or the like, and are provided near the X-ray irradiation port of the X-ray tube 105 in order to adjust the irradiation range of the X-rays.
[0015] The filter in the X-ray aperture 106 changes the radiation quality of the X-rays passing through it depending on its material and thickness, in order to reduce the radiation dose to the subject and improve the image quality of the X-ray image data, thereby reducing soft ray components that are easily absorbed by the subject and high energy components that cause a decrease in image contrast. In addition, the filter changes the X-ray dose and irradiation range depending on its material, thickness, position, etc., and attenuates the X-rays so that the X-rays irradiated to the breast P have a predetermined distribution.
[0016] For example, the X-ray aperture 106 has a driving mechanism such as a motor and an actuator, and controls the irradiation of X-rays by operating the driving mechanism under the control of the processing circuitry 114 described later. For example, the X-ray aperture 106 applies a driving voltage to the driving mechanism in response to a control signal received from the processing circuitry 114, thereby adjusting the opening of the aperture blades of the collimator, and controls the irradiation range of the X-rays irradiated to the breast P. Also, for example, the X-ray aperture 106 applies a driving voltage to the driving mechanism in response to a control signal received from the processing circuitry 114, thereby adjusting the position of the filter, and thereby controlling the distribution of the dose of X-rays irradiated to the breast P.
[0017] The X-ray detector 107 is, for example, an X-ray flat panel detector (FPD) having detection elements arranged in a matrix. The X-ray detector 107 detects X-rays irradiated from the X-ray tube 105 and transmitted through the breast P, and outputs a detection signal corresponding to the detected X-ray amount to a signal processing circuit 108. The X-ray detector 107 may be an indirect conversion type detector having a grid, a scintillator array, and a photosensor array, or may be a direct conversion type detector having a semiconductor element that converts incident X-rays into an electric signal.
[0018] For example, the X-ray detector 107 detects an X-ray pulse irradiated from the X-ray tube 105, and generates a detection signal corresponding to the detected X-ray amount. Here, the X-ray detector 107 holds the generated detection signal. After irradiating the X-ray pulse, the X-ray detector 107 outputs the detection signal to the signal processing circuit 108. Then, the signal processing circuit 108 generates projection data based on the detection signal output from the X-ray detector 107, and stores the projection data in the memory 112.
[0019] As shown in FIG. 1, the X-ray diagnostic apparatus 10 also includes an input interface 109, an elevation drive device 110, an X-ray high voltage device 111, a memory 112, a display 113, and a processing circuit 114.
[0020] The input interface 109 receives various input operations from an operator, converts the received input operations into electrical signals, and outputs the electrical signals to the processing circuitry 114. For example, the input interface 109 is realized by a mouse, a keyboard, a trackball, a switch, a button, a joystick, a touch pad that performs input operations by touching an operation surface, a touch screen in which a display screen and a touch pad are integrated, a non-contact input circuit using an optical sensor, a voice input circuit, or the like. The input interface 109 may be configured as a tablet terminal or the like that can wirelessly communicate with the processing circuitry 114. The input interface 109 is not limited to only those that have physical operation parts such as a mouse and a keyboard. For example, an electrical signal processing circuit that receives an electrical signal corresponding to an input operation from an external input device provided separately from the X-ray diagnostic apparatus 10 body and outputs the electrical signal to the processing circuitry 114 is also included in the examples of the input interface 109.
[0021] The lifting drive device 110 is connected to the imaging table 103 and the compression plate 104. For example, the lifting drive device 110 lifts and lowers the imaging table 103 in the up-down direction. Also, for example, the lifting drive device 110 lifts and lowers the compression plate 104 in the up-down direction (the direction toward and away from the imaging table 103). For example, the lifting drive device 110 has a drive mechanism such as a motor and an actuator, and controls the lifting and lowering of the imaging table 103 and the compression plate 104 by operating the drive mechanism under the control of the processing circuit 114.
[0022] The X-ray high voltage device 111 supplies a high voltage to the X-ray tube 105 under the control of the processing circuit 114. For example, the X-ray high voltage device 111 has electric circuits such as a transformer and a rectifier, and includes a high voltage generating device that generates a high voltage to be applied to the X-ray tube 105, and an X-ray control device that controls the output voltage according to the X-rays irradiated by the X-ray tube 105. The high voltage generating device may be of a transformer type or an inverter type.
[0023] The memory 112 is realized by, for example, a semiconductor memory element such as a RAM or a flash memory, a hard disk, an optical disk, etc. For example, the memory 112 stores projection data generated by the signal processing circuit 108, a three-dimensional image (volume data) generated by the processing circuit 114 based on the projection data, a two-dimensional image reflecting information in a three-dimensional space, etc. Also, for example, the memory 112 stores a program for enabling a circuit included in the X-ray diagnostic apparatus 10 to realize its function. Note that the memory 112 may be realized by a group of servers (cloud) connected to the X-ray diagnostic apparatus 10 via a network NW.
[0024] The display 113 displays various information. For example, the display 113 displays a GUI for receiving various instructions, various settings, and the like from an operator via the input interface 109. The display 113 also displays various image data collected about the breast P. For example, the display 113 sequentially displays a plurality of slices included in the volume data. For example, the display 113 also displays a two-dimensional image reflecting information in a three-dimensional space. For example, the display 113 is a liquid crystal display or a CRT display. The display 113 may be a desktop type, or may be configured as a tablet terminal or the like capable of wireless communication with the main body of the X-ray diagnostic apparatus 10. The display 113 is an example of a display unit.
[0025] 1, the X-ray diagnostic apparatus 10 is described as having the display 113, but the X-ray diagnostic apparatus 10 may have a projector instead of or in addition to the display 113. The projector can project onto a screen, a wall, a floor, the body surface of a patient, etc. under the control of the processing circuitry 114. As an example, the projector can also project onto any plane, object, space, etc. by projection mapping. Such a projector is an example of a display unit.
[0026] The processing circuit 114 controls the operation of the entire X-ray diagnostic apparatus 10 by executing an acquisition function 114a, an image generation function 114b, an output function 114c, and a reception function 114d. The acquisition function 114a is an example of an acquisition unit. The image generation function 114b is an example of an image generation unit. The output function 114c is an example of a display control unit. The reception function 114d is an example of a reception unit.
[0027] For example, the processing circuitry 114 reads out from the memory 112 a program corresponding to the collecting function 114a and executes it to capture the breast P by tomosynthesis to collect a plurality of projection data. The processing circuitry 114 also reads out from the memory 112 a program corresponding to the image generating function 114b and executes it to generate a plurality of slices and a two-dimensional image reflecting information on a three-dimensional space from a plurality of projection data. The processing circuitry 114 also reads out from the memory 112 a program corresponding to the output function 114c and executes it to display one of the plurality of slices as a slice to be displayed on the display unit, or to display a two-dimensional image on the display unit. The processing circuitry 114 also reads out from the memory 112 a program corresponding to the receiving function 114d and executes it to receive a designation of a position on a slice to be displayed. Details of the processing by the collecting function 114a, the image generating function 114b, the output function 114c, and the receiving function 114d will be described later.
[0028] 1, each processing function is stored in the memory 112 in the form of a program executable by a computer. The signal processing circuit 108 and the processing circuit 114 are processors that realize the function corresponding to each program by reading and executing the program from the memory 112. In other words, the signal processing circuit 108 and the processing circuit 114 in a state where a program has been read out have the function corresponding to the read out program.
[0029] 1, the collection function 114a, the image generation function 114b, the output function 114c, and the reception function 114d are realized by a single processing circuit 114. However, the processing circuit 114 may be configured by combining a plurality of independent processors, and each processor may execute a program to realize the functions. Furthermore, each processing function of the processing circuit 114 may be realized by being appropriately distributed or integrated into a single or a plurality of processing circuits.
[0030] The processing circuitry 114 may also realize the functions by using a processor of an external device connected via a network NW. For example, the processing circuitry 114 reads out and executes a program corresponding to each function from the memory 112, and realizes each function shown in FIG. 1 by using a server group (cloud) connected to the X-ray diagnostic apparatus 10 via the network NW as a computational resource.
[0031] The above describes an example of the overall configuration of the X-ray diagnostic apparatus 10. With this configuration, the X-ray diagnostic apparatus 10 supports image diagnosis using tomosynthesis imaging through processing by the processing circuitry 34.
[0032] First, tomosynthesis imaging will be described. In the case of a mammography apparatus, first, a breast P, which is an object, is placed on an imaging table 103, and then compressed between the imaging table 103 and a compression plate 104. Then, the acquisition function 114a performs tomosynthesis imaging of the breast P in the compressed state, and acquires a plurality of projection data. That is, the acquisition function 114a acquires a plurality of projection data with different projection angles by irradiating the breast P with X-rays while changing the irradiation angle of the X-rays.
[0033] The collection of multiple projection data will be described below with reference to FIGS. 2A, 2B, and 2C. FIG. 2A shows a case where the X-ray tube 105 is located at position S1. FIG. 2B shows a case where the X-ray tube 105 is located at position S2. FIG. 2C shows a case where the X-ray tube 105 is located at position S3. As shown in FIGS. 2A, 2B, and 2C, the X-ray tube 105 moves on an orbit including positions S1, S2, and S3. Also, the dashed lines in FIGS. 2A, 2B, and 2C indicate a portion of the X-rays emitted from the X-ray tube 105. As shown in FIGS. 2A, 2B, and 2C, the X-ray tube 105 moves so as to change the irradiation angle of the X-rays with respect to the breast P.
[0034] Specifically, the acquisition function 114a first irradiates X-rays from the X-ray tube 105 at position S1 to the breast P as shown in the upper diagram of FIG. 2A. Here, the X-rays that have passed through the breast P are detected by the X-ray detector 107. Furthermore, the signal processing circuit 108 generates projection data A101 shown in the lower diagram of FIG. 2A based on the detection signal output from the X-ray detector 107. In the projection data A101, parts a, b, and c of the breast P are projected at the positions shown in the lower diagram of FIG. 2A, respectively.
[0035] Next, as shown in the upper diagram of FIG. 2B, the collection function 114a changes the X-ray irradiation angle from the state shown in FIG. 2A, and causes the X-ray tube 105 at position S2 to irradiate X-rays onto the breast P. Here, the X-rays that have passed through the breast P are detected by the X-ray detector 107. Furthermore, the signal processing circuit 108 generates projection data A102 shown in the lower diagram of FIG. 2B based on the detection signal output from the X-ray detector 107. In the projection data A102, parts a, b, and c of the breast P are projected so as to be superimposed on the positions shown in the lower diagram of FIG. 2B.
[0036] Furthermore, as shown in the upper diagram of FIG. 2C, the acquisition function 114a changes the X-ray irradiation angle from the state shown in FIG. 2B, and causes the X-ray tube 105 at position S3 to irradiate X-rays onto the breast P. Here, the X-rays that have passed through the breast P are detected by the X-ray detector 107. Furthermore, the signal processing circuit 108 generates projection data A103 shown in the lower diagram of FIG. 2C based on the detection signal output from the X-ray detector 107. In the projection data A103, parts a, b, and c of the breast P are projected at the positions shown in the lower diagram of FIG. 2C, respectively.
[0037] For example, the collecting function 114a continuously changes the position of the X-ray tube 105 and generates X-rays when the X-ray tube 105 reaches position S1, position S2, position S3, etc. Also, for example, the collecting function 114a alternately repeats the movement of the X-ray tube 105 and the irradiation of X-rays, thereby generating X-rays from the X-ray tube 105 stopped at position S1, position S2, position S3, etc. Note that the trajectory of the movement of the X-ray tube 105 may be an arc or a straight line as shown in Figures 2A, 2B, and 2C, or may be another trajectory.
[0038] 2A to 2C, the acquisition function 114a controls the operations of the X-ray tube 105, the X-ray detector 107, the signal processing circuit 108, etc. to perform tomosynthesis imaging of the breast P and acquire a plurality of projection data. The acquisition function 114a may perform various correction processes, such as logarithmic conversion processing, offset correction, sensitivity correction, and beam hardening correction, on the acquired projection data.
[0039] In addition, the angle of tomosynthesis imaging can be changed as appropriate. For example, the acquisition function 114a can perform tomosynthesis imaging by fixing the positions of the imaging table 103 and the compression plate 104 in the MLO (Mediolateral-Oblique) direction or the CC (Cranio-Caudal) direction.
[0040] Next, the image generating function 114b generates a three-dimensional image (volume data) from a plurality of projection data collected by tomosynthesis imaging. An example of a process for generating volume data will be described below with reference to Fig. 3. In Fig. 3, as an example, a case where the volume data is reconstructed by the shift-and-add method will be described.
[0041] For example, the image generating function 114b adds the projection data A101, A102, and A103 shown in the upper diagram of Fig. 3 so as to align the positions where the region a is projected on each projection data, and generates a slice shown in the lower diagram of Fig. 3. In the slice in the lower diagram of Fig. 3, the portions where the region a is projected in the projection data A101, A102, and A103 are added while aligning their positions, so that the region a is clearly expressed.
[0042] Here, each projection data also includes signals indicating parts b and c, but because they are shifted and overlapped in the slices in the lower diagram of Fig. 3, the signals of parts b and c are diffused and blurred. Therefore, only part a is clearly displayed in the lower diagram of Fig. 3. That is, in Fig. 3, the image generation function 114b can generate slices using a plane including part a in the breast P as the reconstruction plane.
[0043] In FIG. 3, the direction parallel to the reconstruction plane is the X direction. The direction parallel to the reconstruction plane and perpendicular to the X direction is the Y direction. That is, as shown in FIG. 3, the X direction and the Y direction are parallel to the slice. In the following, the direction perpendicular to the X direction and the Y direction is the Z direction. That is, the Z direction is perpendicular to the slice. The Z direction is also referred to as the slice direction.
[0044] Similarly, the image generation function 114b can generate a slice in which the part b is clearly represented, using a plane including the part b in the breast P as a reconstruction plane. Similarly, the image generation function 114b can generate a slice in which the part c is clearly represented, using a plane including the part c in the breast P as a reconstruction plane.
[0045] For example, as shown in Fig. 4, the image generating function 114b can generate "50" slices from slice B101 to slice B150. In other words, the image generating function 114b can generate volume data including "50" slices. Note that the number of slices to be generated is not limited to "50", and the image generating function 114b can generate any number of slices while shifting the reconstruction plane in the slice direction.
[0046] Furthermore, the image generating function 114b generates a two-dimensional image C1 that reflects information in a three-dimensional space based on a plurality of projection data collected by tomosynthesis imaging. For example, the image generating function 114b generates a composite 2D image that combines a plurality of slices as the two-dimensional image C1. The two-dimensional image C1 is an example of a first two-dimensional image. The generating conditions for the two-dimensional image C1 are also referred to as first generating conditions.
[0047] For example, the image generating function 114b generates a two-dimensional image C1 by synthesizing slices B101 to B150 as shown in Fig. 4. For example, the image generating function 114b generates the two-dimensional image C1 by calculating an average value of pixel values of each slice for each pixel. Note that the method of generating the two-dimensional image C1 is not particularly limited. For example, the image generating function 114b can also generate the two-dimensional image C1 by maximum intensity projection (MIP) or minimum intensity projection (MIP), etc.
[0048] The two-dimensional image C1 is generated, for example, by synthesizing a plurality of slices according to preset generation conditions (parameters). As another example, the two-dimensional image C1 is generated based on the analysis results by computer-aided detection (CAD). For example, the image generation function 114b performs CAD analysis on a plurality of slices, sets a large weight for a slice in which a lesion is detected, and performs weighted averaging processing among the plurality of slices to generate the two-dimensional image C1.
[0049] Here, the output function 114c can display the slices B101 to B150 and the two-dimensional image C1 on the display 113. For example, the output function 114c displays any one of the slices B101 to B150 as a slice to be displayed on the display 113 in response to an input operation from a user. For example, a user such as a doctor can observe a slice in which a lesion is depicted to determine its condition and consider the necessity of treatment. However, interpretation of multiple slices takes time, which places a heavy burden on the doctor who interprets the images.
[0050] On the other hand, the two-dimensional image C1 is a summary image that summarizes information in three-dimensional space on a plane, and by using the two-dimensional image C1 as the subject of image interpretation, the burden on the image interpreting doctor is reduced. However, in the two-dimensional image C1, much of the information contained in multiple slices is summarized in one image, which may make it difficult to visualize the lesion. In order to improve the visibility of the lesion, it is possible to generate the two-dimensional image C1 by weighting the information contained in multiple slices, but in this case, there is a possibility that some of the information may be missing.
[0051] Therefore, the X-ray diagnostic apparatus 10 supports image diagnosis using tomosynthesis imaging through processing by the processing circuitry 114, which will be described below. The processing by the processing circuitry 114 will be described below with reference to FIG.
[0052] First, the output function 114c displays slice Bx shown in Fig. 5 on the display 113. Slice Bx is a slice to be displayed selected by the user from slices B101 to B150, for example. For example, the user can switch the slice to be displayed as slice Bx between slices B101 to B150 by operating the wheel of the mouse or the like. That is, the user can advance through the slices by operating the wheel of the mouse or the like.
[0053] Here, the reception function 114d receives a designation of a position on the slice Bx. For example, the user operates a pointer D shown in FIG. 5 by operating a mouse, and clicks and designates an important point L1. The important point L1 is, for example, a position on the slice Bx where a lesion is suspected. Note that the reception function 114d may attach, for example, an annotation or coordinate information to the slice Bx as information indicating the important point L1.
[0054] The method of specifying the position on the slice Bx is not particularly limited, and various modifications are possible. For example, the reception function 114d may accept the position of the pointer D as the specified position regardless of the presence or absence of a click operation. Also, for example, when the display 113 is a touch screen, the reception function 114d may accept the position tapped on the display 113 as the specified position.
[0055] Next, the image generating function 114b generates a two-dimensional image C2 by synthesizing a plurality of slices under a generating condition according to the designated position. The two-dimensional image C2 is a synthesized 2D image generated under a second generating condition different from that of the two-dimensional image C1 shown in FIG. 4, and is an example of a second two-dimensional image.
[0056] Specifically, the image generating function 114b generates the two-dimensional image C2 under conditions in which the weight of the designated position is increased so that the designated position is emphasized. For example, the image generating function 114b generates the two-dimensional image C2 by setting a large weight for the slice whose position is designated and performing weighted average processing among a plurality of slices. Also, for example, the image generating function 114b generates the two-dimensional image C2 by setting a large weight for the pixel at the designated position among the slice whose position is designated and performing weighted average processing among a plurality of slices. Also, for example, the image generating function 114b generates the two-dimensional image C2 by emphasizing the frequency band held by the image at the designated position by multi-resolution analysis or the like.
[0057] Then, the output function 114c displays a portion of the two-dimensional image C2 including a position corresponding to the position specified in the slice Bx in a superimposed manner near the position specified in the slice Bx. Specifically, in FIG. 5, the important point L1 is described as the position specified in the slice Bx. Also, in FIG. 5, the portion including the important point L1 in the slice Bx is shown by a rectangular dashed line. The output function 114c displays a portion of the two-dimensional image C2 including a position corresponding to the position specified in the slice Bx in a superimposed manner near the important point L1. That is, the output function 114c displays a portion of the two-dimensional image C2 corresponding to the dashed line region in FIG. 5 in a small window (magnifying glass) near the important point L1.
[0058] A user can evaluate the two-dimensional image C2 by referring to the display of Fig. 5. That is, the user can evaluate whether the important point L1 specified in the slice Bx appears appropriately in the two-dimensional image C2.
[0059] 5 shows a case where the position of the important point L1 is specified, but the user can change the specified position as appropriate. At this time, the range of the displayed two-dimensional image C2 is also changed as appropriate. That is, the output function 114c displays a portion of the two-dimensional image C2 including a position corresponding to the newly specified position in the slice Bx in a superimposed manner near the newly specified position. That is, the output function 114c can cause a small window (loupe) showing the two-dimensional image C2 to follow the movement of the specified position.
[0060] Here, if the important point L1 does not appear properly in the two-dimensional image C2, the user can request regeneration of the two-dimensional image C2. When the reception function 343 receives an input operation to regenerate the two-dimensional image C2, the image generation function 114b changes parameters related to the generation process, such as changing a weighting value in the weighted average process, and regenerates the two-dimensional image C2. For example, the image generation function 114b regenerates the two-dimensional image C2 when a double-click operation is performed on the displayed two-dimensional image C2 is used as a trigger.
[0061] Furthermore, if the important point L1 does not appear properly in the two-dimensional image C2, the user may treat the two-dimensional image C2 as a failure to be photographed. For example, the output function 114c displays a reject button R near the display frame of the two-dimensional image C2, and the reception function 114d receives the selection of the reject button R as an input operation to treat the two-dimensional image C2 as a failure to be photographed.
[0062] If the two-dimensional image C2 is not determined to be a defective image, the output function 114c transmits the two-dimensional image C2 to, for example, a picture archiving and communication system (PACS) to register it.
[0063] On the other hand, when the two-dimensional image C2 is determined to be a failure, the output function 114c transmits the two-dimensional image C2 to a server for failed images, for example. The image determined to be a failure can be used, for example, for analysis to clarify the cause of the failure and reduce the occurrence rate of the failure. Alternatively, when the two-dimensional image C2 is determined to be a failure, the two-dimensional image C2 may be only stored in the memory 112 and not transmitted to the PACS or other servers. Alternatively, when the two-dimensional image C2 is determined to be a failure, the two-dimensional image C2 may be deleted.
[0064] When the two-dimensional image C2 is determined to be a failure, information regarding the failure may be generated. For example, when the two-dimensional image C2 is determined to be a failure because the important point L1 shown in Fig. 5 does not appear in the two-dimensional image C2, the reason and the position (coordinate information, etc.) of the important point L1 may be logged or reported as information regarding the failure.
[0065] Although an example has been described in which the input operation of whether or not the two-dimensional image C2 is to be rejected is received by the reject button R, the embodiment is not limited to this. For example, after the display of FIG. 5, when the slice to be displayed as slice Bx is switched (when the slice is forwarded) or when an operation of specifying a position on the slice is performed, the reception function 114d may receive the operation as an input operation to the effect that the two-dimensional image C2 is to be rejected. That is, when such an operation is performed, the important point L1 does not appear properly in the two-dimensional image C2, and it can be estimated that a check by the slice Bx has started, so the reception function 114d can determine that the two-dimensional image C2 is to be rejected.
[0066] Next, an example of the procedure of processing by the X-ray diagnostic apparatus 10 will be described with reference to FIG. 6. FIG. 6 is a flowchart for explaining a series of processing flows of the X-ray diagnostic apparatus 10 according to the first embodiment. Step S101 corresponds to the acquisition function 114a. Steps S102 and S105 correspond to the image generation function 114b. Steps S103, S106, S108, and S109 correspond to the output function 114c. Steps S104 and S107 correspond to the reception function 114d.
[0067] First, the processing circuitry 114 executes tomosynthesis imaging to collect a plurality of projection data (step S101). Next, the processing circuitry 114 generates a plurality of slices and a two-dimensional image from the plurality of projection data (step S102). The processing circuitry 114 also causes the display 113 to display one of the plurality of generated slices as a slice to be displayed (step S103). Note that the processing circuitry 114 may appropriately display the two-dimensional image generated in step S102 in response to, for example, a user operation.
[0068] Next, the processing circuit 114 accepts a designation of a position on the slice to be displayed (step S104), and regenerates a two-dimensional image under a condition where the weight of the designated position is increased (step S105). In addition, the processing circuit 114 displays a portion of the regenerated two-dimensional image including the position corresponding to the designation accepted in step S104 in a superimposed manner near the designated position on the slice to be displayed (step S106).
[0069] Here, the processing circuitry 114 accepts an input operation of whether or not to accept the two-dimensional image regenerated in step S105 from the user who has referred to the display in step S106 (step S107). That is, the processing circuitry 114 accepts an input operation of whether or not to reject the two-dimensional image via, for example, the reject button R shown in FIG.
[0070] When an input operation to the effect that the image is permitted is received (Yes in step S107), the processing circuitry 114 registers the two-dimensional image in the PACS or the like (step S108). On the other hand, when an input operation to the effect that the image is not permitted is received (No in step S107), the processing circuitry 114 omits step S108 and registers the slices generated in step S102 in the PACS or the like (step S109). That is, when the two-dimensional image is not to be treated as a failed image, the processing circuitry 114 registers the two-dimensional image and the slices in the PACS or the like, and when the two-dimensional image is to be treated as a failed image, the processing circuitry 114 registers only the slices in the PACS or the like.
[0071] As described above, according to the first embodiment, the acquisition function 114a acquires a plurality of projection data by performing tomosynthesis imaging of the subject. The image generation function 114b generates a plurality of slices and a two-dimensional image based on the plurality of projection data. The output function 114c displays one of the plurality of slices as a display target slice on the display unit. The reception function 114d receives a designation of a position on the display target slice. Furthermore, the output function 114c displays a portion of the two-dimensional image including a position corresponding to the designated position on the display target slice in a superimposed manner near the designated position on the display target slice. With this configuration, the X-ray diagnostic apparatus 10 according to the first embodiment supports image diagnosis by tomosynthesis imaging.
[0072] Specifically, it is preferable that the two-dimensional image reflecting the information in the three-dimensional space includes the findings that the user considers important, such as the important point L1 in FIG. 5. However, depending on the conditions for generating the two-dimensional image, some information may be missing from the two-dimensional image. In contrast, the X-ray diagnostic apparatus 10 according to the first embodiment displays the two-dimensional image in a nearby small window, making it possible to easily determine whether the findings that the user considers important on the slice to be displayed appear in the two-dimensional image. That is, the user can easily determine whether the two-dimensional image is suitable for diagnosis.
[0073] Although it is possible to simply display the slice to be displayed and the two-dimensional image side by side or to switch between them, what is important in evaluating the two-dimensional image is whether or not it contains findings that the user considers important. According to the X-ray diagnostic device 10, a small window display of a narrow range that may contain findings that the user considers important is performed, so that the two-dimensional image can be evaluated efficiently.
[0074] Furthermore, if it is determined that the generated two-dimensional image is not suitable for diagnosis, it is possible to take appropriate measures. For example, if it is determined that the generated two-dimensional image is not suitable for diagnosis, the two-dimensional image is treated as a failure, and a new two-dimensional image is generated under changed generation conditions, or a diagnosis based on multiple slices is recommended.
[0075] As described above, according to the first embodiment, the X-ray diagnostic apparatus 10 generates a two-dimensional image under the condition that the weight of the position designated on the slice to be displayed is increased. In such a two-dimensional image, the findings that the user considers important, such as the important point L1 in FIG. 5, are emphasized, and the image is often suitable for diagnosis. This allows the X-ray diagnostic apparatus 10 to reduce the rate at which the generated two-dimensional images are treated as failures, and improve diagnostic performance.
[0076] Second Embodiment In addition to the first embodiment described above, various modifications may be made.
[0077] For example, in Fig. 5, an example has been described in which a two-dimensional image C2 is superimposed and displayed near a position on slice Bx for which a designation has been accepted. That is, an example has been described in which a two-dimensional image C2 generated under a generation condition corresponding to a position on slice Bx for which a designation has been accepted is displayed in a small window. However, the two-dimensional image to be displayed in the small window is not limited to the two-dimensional image C2.
[0078] For example, the output function 114c may display a portion of the two-dimensional image C1 including a position corresponding to the position on the slice Bx for which the designation was accepted in a superimposed manner in the vicinity of the position on the slice Bx for which the designation was accepted. That is, the output function 114c may display the two-dimensional image C1 in a small window (magnifying glass) in the same manner as the two-dimensional image C2. It is fully expected that the two-dimensional image C1 may be suitable for diagnosis, and such a display makes it possible to easily determine whether the two-dimensional image C1 is suitable for diagnosis, for example, depending on whether the important point L1 appears in the two-dimensional image C1. When the two-dimensional image C1 is displayed in a small window, the generation process of the two-dimensional image C2 may be omitted.
[0079] 5, an example has been described in which a portion of the two-dimensional image C2 including a position corresponding to a position on the slice Bx for which a designation has been accepted is displayed. That is, an example has been described in which only a portion of the two-dimensional image C2 is displayed in a small window. However, the embodiment is not limited to this, and the entire two-dimensional image C2 may be displayed. For example, the output function 114c may display the two-dimensional image C2 alongside the slice Bx, or may switch between the slice Bx and the two-dimensional image C2 in response to an input operation from the user.
[0080] In the above-described embodiment, the two-dimensional image C1 and the two-dimensional image C2 are generated based on the slices B101 to B150 including the slices to be displayed, but the embodiment is not limited to this.
[0081] For example, the image generating function 114b may generate a plurality of slices different from slices B101-B150 based on a plurality of projection data collected by tomosynthesis imaging of a subject, and generate at least one of a two-dimensional image C1 and a two-dimensional image C2 based on the plurality of slices. Note that a plurality of slices including a slice to be displayed (for example, slices B101-B150 including slice Bx shown in FIG. 5) are also referred to as a first plurality of slices. Also, a plurality of slices generated from a plurality of projection data under conditions different from those of the first plurality of slices are also referred to as a second plurality of slices.
[0082] As an example, the image generating function 114b generates slices B101 to B150 by the shift-and-add method, and the output function 114c displays one of the slices B101 to B150 as a slice to be displayed. Furthermore, the image generating function 114b generates a second plurality of slices by any method other than the shift-and-add method, and generates at least one of the two-dimensional image C1 and the two-dimensional image C2 based on the second plurality of slices.
[0083] As another example, the image generating function 114b generates a first plurality of slices by an arbitrary method such as a shift-and-add method, and the output function 114c displays one of the first plurality of slices as a slice to be displayed. Furthermore, the image generating function 114b generates a second plurality of slices based on the first plurality of slices, and generates at least one of the two-dimensional image C1 and the two-dimensional image C2 based on the second plurality of slices.
[0084] For example, the image generating function 114b generates the second plurality of slices by performing arbitrary image processing such as noise reduction processing and edge enhancement processing on the first plurality of slices. Also, for example, the image generating function 114b performs arbitrary image processing for each frequency band on the first plurality of slices, and generates the second plurality of slices by synthesizing the data of each frequency band after the image processing. Alternatively, the image generating function 114b may generate a plurality of slices different from the first plurality of slices by any of the above-mentioned methods, and generate the second plurality of slices by synthesizing the slices with the first plurality of slices.
[0085] In the above embodiment, an example of generating a two-dimensional image based on a plurality of slices has been described, but the embodiment is not limited to this. That is, the image generating function 114b may generate at least one of the two-dimensional image C1 and the two-dimensional image C2 directly from a plurality of projection data without going through a process of generating a plurality of slices.
[0086] In the above embodiment, the X-ray diagnostic apparatus 10 is a mammography apparatus, but the embodiment is not limited to this. That is, the present invention can be applied to any type of X-ray diagnostic apparatus 10 capable of performing tomosynthesis imaging.
[0087] Also, some of the various processes described above can be executed by a device other than the X-ray diagnostic device 10. In the following, as an example, a medical image processing device 30 included in the medical image processing system 1 of Fig. 7 executes the process for supporting the image diagnosis by the tomosynthesis imaging described above. As shown in Fig. 7, the medical image processing system 1 according to the second embodiment includes the X-ray diagnostic device 10, the image storage device 20, and the medical image processing device 30. As shown in Fig. 1, the X-ray diagnostic device 10, the image storage device 20, and the medical image processing device 30 are connected to each other via a network NW.
[0088] As described above, the X-ray diagnostic apparatus 10 performs tomosynthesis imaging of a subject to collect a plurality of projection data. The collected projection data is transmitted to the medical image processing apparatus 30 via the image storage apparatus 20 or directly.
[0089] The image storage device 20 is a device that stores projection data and various image data. For example, the image storage device 20 acquires projection data collected by the X-ray diagnostic device 10 and various image data generated by the medical image processing device 30 via the network NW, and stores them in a memory provided inside or outside the device. The image storage device 20 is, for example, a PACS server.
[0090] The medical image processing device 30 acquires projection data via the network NW, and executes processes similar to the image generation function 114b, the output function 114c, and the reception function 114d described above. For example, the medical image processing device 30 is realized by a computer device such as a workstation.
[0091] In addition, the X-ray diagnostic apparatus 10, the image storage apparatus 20, and the medical image processing apparatus 30 may be installed in any location as long as they can be connected via the network NW. For example, the medical image processing apparatus 30 may be installed in a hospital different from the hospital where the X-ray diagnostic apparatus 10 is installed. In other words, the network NW may be configured as a closed local network within the hospital, or may be a network via the Internet. In addition, although one X-ray diagnostic apparatus 10 is shown in FIG. 1, the medical image processing system 1 may include multiple X-ray diagnostic apparatuses 10.
[0092] 7, the medical image processing device 30 has an input interface 31, a display 32, a memory 33, and a processing circuit 34. The input interface 31, the display 32, and the memory 33 can be realized in the same manner as the above-mentioned input interface 109, the display 113, and the memory 112, and therefore a description thereof will be omitted.
[0093] The processing circuitry 34 controls the operation of the entire medical image processing device 30 by executing an image generation function 341, an output function 342, and a reception function 343. Here, the image generation function 341 is a function similar to the above-mentioned image generation function 114b, and is an example of an image generation unit. The output function 342 is a function similar to the above-mentioned output function 114c, and is an example of a display control unit. The reception function 343 is a function similar to the above-mentioned reception function 114d, and is an example of a reception unit.
[0094] 7, each processing function is stored in the form of a program executable by a computer in a memory 33. The processing circuitry 34 is a processor that realizes a function corresponding to each program by reading and executing the program from the memory 33. In other words, the processing circuitry 34 in a state in which each program has been read has a function corresponding to the read program.
[0095] 7, the image generating function 341, the output function 342, and the reception function 343 are realized by a single processing circuit 34. However, the processing circuit 34 may be configured by combining a plurality of independent processors, and each processor may execute a program to realize the functions. Furthermore, each processing function of the processing circuit 34 may be realized by being appropriately distributed or integrated in a single or a plurality of processing circuits.
[0096] The processing circuitry 34 may also realize the functions by using a processor of an external device connected via a network NW. For example, the processing circuitry 34 reads out and executes a program corresponding to each function from the memory 33, and realizes each function shown in FIG. 7 by using a server group (cloud) connected to the medical image processing device 30 via the network NW as a computational resource.
[0097] For example, the image generating function 341 generates a first plurality of slices based on a plurality of projection data obtained by tomosynthesis imaging. The output function 342 causes the display 32 to display one of the first plurality of slices as a slice to be displayed. The reception function 343 receives a designation of a position on the slice to be displayed. Note that the generation of the slices is performed in the X-ray diagnostic apparatus 10, and the image generating function 341 may obtain the generated slices via the network NW.
[0098] Also, the image generating function 341 generates a two-dimensional image that reflects information on the three-dimensional space. For example, the image generating function 341 generates a two-dimensional image based on a first plurality of slices. For example, the image generating function 341 generates a two-dimensional image based on a second plurality of slices generated under conditions different from the first plurality of slices. For example, the image generating function 341 generates a two-dimensional image directly from a plurality of projection data without going through a process of generating a plurality of slices.
[0099] Furthermore, the output function 342 displays a portion of the two-dimensional image including a position corresponding to the designated position in the vicinity of the designated position on the slice to be displayed, in a superimposed manner. That is, the output function 342 displays the two-dimensional image in a small window. Here, the two-dimensional image displayed in the small window may be the above-mentioned two-dimensional image C1 or may be the two-dimensional image C2. As for the display method, various modifications are possible as described above.
[0100] The term "processor" used in the above description means a circuit such as a CPU (Central Processing Unit), a GPU (Graphics Processing Unit), an Application Specific Integrated Circuit (ASIC), a programmable logic device (e.g., a Simple Programmable Logic Device (SPLD), a Complex Programmable Logic Device (CPLD), and a Field Programmable Gate Array (FPGA)). The processor realizes functions by reading and executing a program stored in the memory 33 or memory 112.
[0101] 1 and 7, a single memory 33 or memory 112 is described as storing a program corresponding to each processing function. However, the embodiment is not limited to this. For example, a configuration may be adopted in which a plurality of memories 33 are distributed and the processing circuit 34 reads out the corresponding program from each memory 33. Similarly, a configuration may be adopted in which a plurality of memories 112 are distributed and the processing circuit 114 reads out the corresponding program from each memory 112. Also, instead of storing the program in the memory 33 and the memory 112, the program may be directly built into the circuit of the processor. In this case, the processor realizes the function by reading and executing the program built into the circuit.
[0102] Each component of each device according to the first and second embodiments is a functional concept, and does not necessarily have to be physically configured as shown in the drawings. In other words, the specific form of distribution and integration of each device is not limited to that shown in the drawings, and all or a part of them can be functionally or physically distributed and integrated in any unit according to various loads, usage conditions, etc. Furthermore, all or any part of the processing functions performed by each device can be realized by a CPU and a program analyzed and executed by the CPU, or can be realized as hardware using wired logic.
[0103] The medical image processing method described in the first and second embodiments can be realized by executing a prepared medical image processing program on a computer such as a personal computer or a workstation. This medical image processing program can be distributed via a network such as the Internet. This medical image processing program can also be recorded on a non-transitory computer-readable recording medium such as a hard disk, a flexible disk (FD), a CD-ROM, an MO, or a DVD, and executed by being read out from the recording medium by a computer.
[0104] According to at least one of the embodiments described above, image diagnosis using tomosynthesis imaging can be supported.
[0105] Although some embodiments of the present invention have been described, these embodiments are presented as examples and are not intended to limit the scope of the invention. These embodiments can be implemented in various other forms, and various omissions, substitutions, and modifications can be made without departing from the spirit of the invention. These embodiments and their modifications are included in the scope of the invention and its equivalents described in the claims, as well as in the scope and spirit of the invention. [Explanation of symbols]
[0106] 1: Medical image processing system 10: X-ray diagnostic equipment 114: Processing circuit 114a: Collection function 114b: Image generation function 114c: Output function 114d: Reception function 30: Medical image processing device 34: Processing circuit 341: Image generation function 342: Output function 343: Reception function
Claims
1. an acquisition unit that acquires a plurality of projection data by performing tomosynthesis imaging of a subject; an image generator configured to generate a first plurality of slices based on the plurality of projection data; a display control unit that causes a display unit to display any one of the first plurality of slices as a slice to be displayed; a reception unit that receives a designation of a position on the display target slice, The image generating unit generates a two-dimensional image based on the first slices, a second slice generated from the projection data under a condition different from that of the first slices, or the projection data; The display control unit superimposes and displays a portion of the two-dimensional image including a position corresponding to the position for which the designation was accepted on the slice to be displayed in the vicinity of the position for which the designation was accepted.
2. the image generating unit generates a first two-dimensional image under a first generation condition based on the first plurality of slices, the second plurality of slices, or the plurality of projection data, and further generates a second two-dimensional image under a second generation condition different from the first generation condition according to a position for which the designation is accepted; 2. The X-ray diagnostic apparatus according to claim 1, wherein the display control unit causes a portion of the second two-dimensional image including a position corresponding to the position for which the designation was accepted to be superimposed on the slice to be displayed in the vicinity of the position for which the designation was accepted.
3. 3. The X-ray diagnostic apparatus according to claim 2, wherein the image generating unit generates the second two-dimensional image under a condition in which a weight is increased for a position for which the designation is accepted among the first plurality of slices, the second plurality of slices, or the plurality of projection data.
4. 4. The X-ray diagnostic apparatus according to claim 3, wherein the image generator generates the second two-dimensional image by setting a large weight for a slice for which the designation has been accepted and performing weighted averaging processing among the first plurality of slices or the second plurality of slices.
5. 4. The X-ray diagnostic apparatus according to claim 3, wherein the image generating unit generates the second two-dimensional image by setting a large weight for a pixel at a specified position among the slices for which the designation has been accepted, and performing weighted averaging processing among the first plurality of slices or the second plurality of slices.
6. The X-ray diagnostic apparatus according to claim 3 , wherein the image generating unit generates the second two-dimensional image by emphasizing a frequency band contained in an image at a specified position.
7. The X-ray diagnostic apparatus according to claim 2 , wherein the reception unit further receives an input operation of whether or not the second two-dimensional image is to be determined as a defective image.
8. The X-ray diagnostic apparatus according to claim 2 , wherein the accepting unit further accepts an input operation to regenerate the second two-dimensional image.
9. an acquisition unit that acquires a plurality of projection data by performing tomosynthesis imaging of a subject; an image generator configured to generate a first plurality of slices based on the plurality of projection data; a display control unit that causes a display unit to display any one of the first plurality of slices as a slice to be displayed; a reception unit that receives a designation of a position on the display target slice, The image generation unit generates a first two-dimensional image under first generation conditions based on the first plurality of slices, a second plurality of slices generated from the plurality of projection data under conditions different from those of the first plurality of slices, or the plurality of projection data, and further generates a second two-dimensional image under second generation conditions different from the first generation conditions according to a position where the designation is accepted.
10. an image generating unit that generates a first plurality of slices based on a plurality of projection data acquired by performing tomosynthesis imaging on a subject; a display control unit that causes a display unit to display any one of the first plurality of slices as a slice to be displayed; a reception unit that receives a designation of a position on the display target slice, The image generating unit generates a two-dimensional image based on the first slices, a second slice generated from the projection data under a condition different from that of the first slices, or the projection data; The display control unit is a medical image processing device that superimposes a portion of the two-dimensional image including a position corresponding to the position where the specification was accepted, near the position where the specification was accepted on the slice to be displayed.
11. an image generating unit that generates a first plurality of slices based on a plurality of projection data acquired by performing tomosynthesis imaging on a subject; a display control unit that causes a display unit to display any one of the first plurality of slices as a slice to be displayed; a reception unit that receives a designation of a position on the display target slice, The image generation unit generates a first two-dimensional image under first generation conditions based on the first plurality of slices, a second plurality of slices generated from the plurality of projection data under conditions different from those of the first plurality of slices, or the plurality of projection data, and further generates a second two-dimensional image under second generation conditions different from the first generation conditions according to the position where the designation is accepted.
12. generating a first plurality of slices based on a plurality of slices based on a plurality of projection data acquired by tomosynthesis imaging of the subject; displaying any one of the first plurality of slices as a slice to be displayed on a display unit; Accepting a designation of a position on the slice to be displayed; generating a two-dimensional image based on the first slices, a second slice generated from the projection data under a condition different from that of the first slices, or the projection data; A portion of the two-dimensional image including a position corresponding to the position for which the designation has been accepted is superimposed and displayed in the vicinity of the position for which the designation has been accepted on the slice to be displayed. A medical image processing program that causes a computer to carry out processing.
13. generating a first plurality of slices based on a plurality of projection data acquired by tomosynthesis imaging of the object; displaying any one of the first plurality of slices as a slice to be displayed on a display unit; Accepting a designation of a position on the slice to be displayed; A first two-dimensional image is generated under a first generation condition based on the first plurality of slices, a second plurality of slices generated from the plurality of projection data under a condition different from that of the first plurality of slices, or the plurality of projection data, and a second two-dimensional image is generated under a second generation condition different from the first generation condition according to the position for which the designation is accepted. A medical image processing program that causes a computer to carry out processing.
Citation Information
Patent Citations
Providing image information of the object
JP2015515296A