Cover
A tubular knitted fabric cover with water and oil repellent treatment addresses both air permeability and stretchability issues, effectively preventing drug migration and promoting absorption in skin disease treatments.
Patent Information
- Application Number
- JP2024004039
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2024-01-15
- Publication Date
- 2025-07-28
AI Technical Summary
Existing treatments for skin diseases, such as wrap films and bandages, either lack air permeability leading to excessive sweating or have poor stretchability inhibiting movement, or allow excessive drug migration reducing efficacy, without addressing both issues simultaneously.
A tubular knitted fabric cover with water and oil repellent treatment, ensuring air permeability and stretchability while preventing drug transfer.
The cover maintains air permeability and stretchability, preventing drug migration and reducing itching, while promoting effective drug absorption.
Smart Images

Figure 2025110226000001_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to a cover, and more particularly to a cover configured to cover an affected area of a patient having a skin disease.
Background Art
[0002] Japanese Patent Application Publication No. 2012-518099 (Patent Document 1) discloses a textile product for patients having a skin disease. This textile product includes at least one textile layer having polytetrafluoroethylene (PTFE) fibers. In this textile product, the PTFE fibers are present on at least one surface of the textile layer for the purpose of contacting the skin of the patient (see Patent Document 1).
Prior Art Documents
Patent Documents
[0003]
Patent Document 1
Summary of the Invention
Problems to be Solved by the Invention
[0004] In the treatment of patients having a skin disease, in order to promote the transdermal absorption of a topical drug, a wrap film may be wound around the affected area of the patient. However, since the wrap film has no air permeability, excessive sweating may occur when the state of winding the wrap film around the affected area of the patient continues for a long time. In addition, since the wrap film has no stretchability, the movement of the site where the wrap film is wound may be inhibited. On the other hand, although a bandage has air permeability and stretchability, when a bandage is wound around the affected area of the patient, much of the topical drug applied to the affected area migrates to the bandage. As a result, a situation may occur in which the effect of the topical drug is not sufficiently exerted. The above Patent Document 1 does not disclose a solution to such problems.
[0005] The present invention has been made to solve such problems, and an object thereof is to provide a cover configured to cover an affected area of a patient having a skin disease, which has air permeability and elasticity and can suppress the transfer of a coating agent applied to the affected area from the affected area to the cover.
Means for Solving the Problems
[0006] The cover according to the present invention is configured to cover an affected area of a patient having a skin disease. This cover is composed of a tubular knitted fabric. The knitted fabric is subjected to water and oil repellent treatment. This cover is configured to cover the affected area with the coating agent applied.
[0007] According to this cover, since the cover is composed of a knitted fabric, air permeability and elasticity can be ensured. Further, according to this cover, since the knitted fabric is subjected to water and oil repellent treatment, it is possible to suppress the transfer of the coating agent applied to the affected area from the affected area to the cover.
[0008] The affected area covered by the above cover may be a part of the upper limb or lower limb of the patient.
[0009] When the cover is laid flat, the width may be 4 cm or more and 27 cm or less.
[0010] In the above cover, the basis weight of the knitted fabric may be 85 g / m 2 or more and 350 g / m 2 or less.
[0011] The above cover may be seamless.
[0012] The sewing part causes itching for a patient having a skin disease. This cover is seamless. Therefore, according to this cover, since there is no sewing part, it is possible to suppress the occurrence of itching in the patient.
[0013] In the above cover, the knitted fabric is composed of heat-sealable elastic yarn and yarn other than heat-sealable elastic yarn, and may have a fraying prevention function.
[0014] According to this cover, since the knitted fabric has a fraying prevention function, it is possible to suppress fraying of the knitted fabric when the cover is cut to a desired length in the length direction.
[0015] In the above cover, the air permeability measured in accordance with JIS L 1096 may be 25 cm 3 / cm 2 ·s or more, and the elongation rate measured in accordance with JIS L 1096 may be 50% or more.
[0016] According to this cover, since the air permeability measured in accordance with JIS L 1096 is 25 cm 3 / cm 2 ·s or more, and the elongation rate measured in accordance with JIS L 1096 is 50% or more, sufficient air permeability and stretchability can be ensured.
Effects of the Invention
[0017] According to the present invention, there is provided a cover configured to cover an affected part of a patient having a skin disease, which has air permeability and stretchability and can suppress the transfer of a coating agent applied to the affected part from the affected part to the cover.
Brief Description of the Drawings
[0018]
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Mode for Carrying Out the Invention
[0019] Hereinafter, embodiments according to one aspect of the present invention (hereinafter also referred to as "the present embodiment") will be described in detail with reference to the drawings. In the drawings, the same or corresponding parts are denoted by the same reference numerals and their descriptions will not be repeated. Also, each drawing is schematically drawn with appropriate omissions or exaggerations of the subject for ease of understanding.
[0020] [1. Configuration of the Cover] FIG. 1 is a diagram for explaining the use of the cover 10 according to the present embodiment. Referring to FIG. 1, a patient HU1 having a skin disease such as atopic dermatitis often applies a topical drug to each affected area AF1. The cover 10 is used to promote the transdermal absorption of the topical drug. Specifically, the cover 10 is configured to cover each affected area AF1 to which the topical drug is applied. The cover 10 covers, for example, the affected areas AF1 existing in the upper limb AR1 (for example, the joint part of the upper limb AR1) and the lower limb LE1 (for example, the joint part of the lower limb LE1).
[0021] For example, in the treatment of the patient HU1, in order to promote the transdermal absorption of the topical drug, it may be considered to wrap a wrap film around each affected area AF1 to which the topical drug is applied. However, since the wrap film has no air permeability, excessive sweating can occur when the state of the wrap film being wrapped around each affected area AF1 continues for a long time. As a result, skin swelling, eczema, miliaria, etc. may occur. Also, since the wrap film has no stretchability, the movements of the upper limb AR1 and the lower limb LE1 wrapped with the wrap film may be inhibited. On the other hand, although the bandage has air permeability and stretchability, when the bandage is wrapped around each affected area AF1 of the patient HU1, much of the topical drug applied to each affected area AF1 migrates to the bandage. As a result, a situation may occur where the effect of the topical drug is not fully exerted.
[0022] FIG. 2 is a diagram schematically showing the plan view and cross-section of the cover 10 according to the present embodiment. Referring to FIG. 2, the upper figure shows the plan view of the cover 10, and the lower figure shows the cross-section of the cover 10. The cover 10 is composed of a cylindrical knitted fabric with a through-hole HO1 formed inside. The through-hole HO1 extends in the longitudinal direction of the cover 10. The cover 10 is stored, for example, in a state of being wound in the longitudinal direction. The cover 10 of a necessary length is cut according to the area of the affected part AF1 to be covered by the cover 10. For example, by passing the upper limb AR1 or the lower limb LE1 through the through-hole HO1, the cut cover 10 is attached to the upper limb AR1 or the lower limb LE1. Thereby, the affected part AF1 of the patient HU1 is covered by the cover 10.
[0023] The knitted fabric constituting the cover 10 is subjected to water and oil repellent treatment. Examples of the water and oil repellent treatment include fluorine treatment, silicon treatment, and acrylic treatment. According to the cover 10, since the cover 10 is composed of a knitted fabric, air permeability and stretchability can be ensured. Further, according to the cover 10, since the knitted fabric is subjected to water and oil repellent treatment, it is possible to suppress the transfer of the coating agent applied to each affected part AF1 from each affected part AF1 to the cover 10.
[0024] The knitted fabric constituting the cover 10 is knitted into a thin weft knitted fabric by a circular knitting machine as a milling fabric. Since it is knitted by a circular knitting machine, the cover 10 is seamless. Generally, the sewn part causes itching for the patient HU1 having a skin disease. According to the cover 10, since no sewing part is provided, the occurrence of itching in the patient HU1 can be suppressed.
[0025] In addition, the knitted fabric constituting the cover 10 has a fraying prevention function. This knitted fabric is knitted, for example, by plating knitting a heat-sealable elastic yarn and a yarn other than the heat-sealable elastic yarn. Examples of the heat-sealable elastic yarn include low-melting-point polyurethane elastic yarn. Examples of the yarn other than the heat-sealable elastic yarn include cotton and rayon. In the knitted fabric constituting the cover 10, heat setting is applied to the plating knitted fabric, and the heat-sealable elastic yarn is welded to the yarn other than the heat-sealable elastic yarn, thereby realizing the fraying prevention function. According to the cover 10, since the knitted fabric has a fraying prevention function, it is possible to suppress fraying of the knitted fabric when the cover 10 is cut to a desired length in the length direction.
[0026] In addition, the width of the cover 10 when laid flat is, for example, 4 cm or more and 27 cm or less, preferably 5 cm or more and 20 cm or less.
[0027] In addition, the basis weight of the knitted fabric constituting the cover 10 is, for example, 85 g / m 2 or more and 350 g / m 2 or less, preferably 100 g / m 2 or more and 300 g / m 2 or less, and more preferably 150 g / m 2 or more and 270 g / m 2 or less.
[0028] In addition, the fineness of the yarn other than the heat-sealable elastic yarn used in the knitted fabric constituting the cover 10 is, for example, 20 Ne or more and 100 Ne or less, preferably 30 Ne or more and 85 Ne or less, and more preferably 38 Ne or more and 60 Ne or less. The fineness of the heat-sealable elastic yarn used in the knitted fabric constituting the cover 10 is, for example, 15 dtex or more and 160 dtex or less, preferably 20 dtex or more and 80 dtex or less, and more preferably 20 dtex or more and 40 dtex or less.
[0029] In addition, the density of the knitted fabric constituting the cover 10 is 30 / inch or more and 50 / inch or less in the wale, preferably 33 / inch or more and 45 / inch or less, more preferably 35 / inch or more and 40 / inch or less, and 40 / inch or more and 80 / inch or less in the course, preferably 45 / inch or more and 75 / inch or less, more preferably 45 / inch or more and 70 / inch or less.
[0030] In addition, the air permeability of the cover 10 is, for example, 25 cm 3 / cm 2 ·s or more, preferably 35 cm 3 / cm 2 ·s or more, more preferably 50 cm 3 / cm 2 ·s or more. The air permeability of the cover 10 is measured in accordance with JIS L 1096.
[0031] In addition, the elongation rate of the cover 10 is, for example, 50% or more, preferably 70% or more, more preferably 85% or more. The elongation rate of the cover 10 is measured in accordance with JIS L 1096.
[0032] [2. Manufacturing method of the cover] As described above, the knitted fabric constituting the cover 10 is knitted into a thin horizontal knitted fabric by a circular knitting machine as a milling fabric. This knitted fabric is knitted, for example, by plating knitting a heat-fusible elastic yarn and a yarn other than the heat-fusible elastic yarn. Heat setting is applied to the knitted plating fabric. Thereby, the cover 10A before the water and oil repellent treatment is manufactured.
[0033] FIG. 3 is a diagram schematically showing a processing apparatus 100 that applies a water and oil repellent treatment to a cover 10A before the water and oil repellent treatment. Referring to FIG. 3, the processing apparatus 100 performs a water and oil repellent treatment on the cover 10A before the water and oil repellent treatment through padding to manufacture a cover 10 after the water and oil repellent treatment. The processing apparatus 100 includes a water tank 20, nip rolls 30A and 30B, and a drying device 40. In the processing apparatus 100, the cover 10A is wound up by a winding roll (not shown), for example. Thereby, the cover 10A is conveyed from an upstream process to a downstream process.
[0034] The water tank 20 is configured to store a processing liquid LI1. The processing liquid LI1 is a solution containing a water and oil repellent. Examples of the water and oil repellent include a fluorine-based water and oil repellent, a silicon-based water and oil repellent, and an acrylic-based water and oil repellent. When the cover 10A is conveyed into the processing liquid LI1, the cover 10A is immersed in the processing liquid LI1.
[0035] The nip rolls 30A and 30B are arranged at positions facing each other. The cover 10A is sandwiched by the nip rolls 30A and 30B. When the cover 10A is sandwiched by the nip rolls 30A and 30B, the cover 10A is squeezed.
[0036] The drying device 40 includes, for example, a heater and is configured to dry the cover 10A. The heating temperature during drying is, for example, 100°C or higher and 200°C or lower. When the cover 10A is dried, the cover 10 after the water and oil repellent treatment is completed.
[0037] [3. Features] As described above, the cover 10 according to the present embodiment is configured to cover the affected area AF1 of the patient HU1 having a skin disease. The cover 10 is composed of a tubular knitted fabric. The knitted fabric is subjected to water and oil repellent treatment. The cover 10 is configured to cover the affected area AF1 with the applied medicine. According to the cover 10, since the cover 10 is composed of a knitted fabric, air permeability and stretchability can be ensured. Further, according to the cover 10, since the knitted fabric is subjected to water and oil repellent treatment, it is possible to suppress the applied medicine applied to the affected area AF1 from migrating from the affected area AF1 to the cover 10.
[0038] [4. Other Embodiments] The idea of the above-described embodiment is not limited to the embodiment described above. Hereinafter, examples of other embodiments to which the idea of the above-described embodiment can be applied will be described.
[0039] <4-1> In the above embodiment, the knitted fabric constituting the cover 10 does not necessarily have to be a milling fabric. The knitted fabric constituting the cover 10 may be composed of, for example, a cotton knitted fabric.
[0040] <4-2> Further, in the above embodiment, the knitted fabric constituting the cover 10 does not necessarily have to have a fraying prevention function. That is, the knitted fabric constituting the cover 10 may be knitted only with threads other than, for example, heat-sealed elastic threads.
[0041] <4-3> Further, in the above embodiment, the knitted fabric constituting the cover 10 does not necessarily have to be knitted by a circular knitting machine. That is, the cover 10 does not necessarily have to be seamless.
[0042] <4-4> Further, in the above embodiment, the portion where the cover 10 is worn is not limited to the upper limb AR1 and the lower limb LE1. For example, the cover 10 may be worn on the abdomen of the patient HU1.
[0043] The embodiments of the present invention have been illustratively described above. That is, for illustrative purposes, a detailed description and the accompanying drawings have been disclosed. Therefore, among the components described in the detailed description and the accompanying drawings, there may be components that are not essential for solving the problems. Thus, just because those non-essential components are described in the detailed description and the accompanying drawings, they should not be immediately recognized as essential.
[0044] Also, the above embodiments are merely examples of the present invention in every aspect. Various improvements and modifications are possible within the scope of the present invention. For example, at least a part of the configuration of one of the embodiments may be combined with at least a part of the configuration of any other embodiment. That is, in practicing the present invention, a specific configuration can be appropriately adopted according to the embodiment.
Example
[0045] Hereinafter, examples of the present invention will be described. Note that the present invention is not limited to the following examples.
[0046] [1. Examples and Comparative Examples] Fabrics of Examples 1 and 2 and Comparative Examples 2 and 3, and the wrap film of Comparative Example 1 were prepared. The physical properties of the fabric of Example 1 were as follows. The composition was 100% cotton. The fineness of the cotton was 40 count. The density was 36.3 / inch in the wale and 47.7 / inch in the course. The basis weight was 185.9 g / m 2 . The fabric of Example 1 was subjected to water and oil repellent treatment. The conditions of the water and oil repellent treatment were as follows. As the chemical agent, NK Guard S-05 (fluorine-based water and oil repellent) manufactured by Nihon Kayaku Co., Ltd. was used. The non-volatile content was about 30%. In the water and oil repellent treatment, a fluorine compound treatment solution with a chemical concentration of 10% owf prepared by adding distilled water to NK Guard S-05 was used. The fabric was immersed in the fluorine compound treatment solution, and the pulled-up fabric was squeezed with a padder. Then, a water and oil repellent treated fabric was produced by performing tenter treatment in a 120°C environment for 3 minutes.
[0047] The physical properties of the fabric of Example 2 were as follows. The composition was 49.8% rayon, 40.8% cotton, and 9.4% polyurethane. The fineness of the cotton / rayon blended yarn was 55 count. The fineness of the polyurethane was 22 dtex. The density was 39.0 / inch in the wale and 67.3 / inch in the course. The areal density was 244.6 g / m 2 . The fabric of Example 2 was subjected to water and oil repellent treatment. The conditions of the water and oil repellent treatment were the same as those in Example 1.
[0048] The physical properties of the fabric of Comparative Example 2 were the same as those of Example 1. The fabric of Comparative Example 2 was not subjected to water and oil repellent treatment. The physical properties of the fabric of Comparative Example 3 were the same as those of Example 2. The fabric of Comparative Example 2 was not subjected to water and oil repellent treatment.
[0049] [2. Various Evaluations] <2-1. Evaluation of Drug Migration Rate to Fabric> The drug migration rate to the fabric was evaluated according to the following procedure. The coating drug used was Hil Mild, and the active ingredient was a heparin-like substance. (1) 0.02 g was weighed while spreading the coating drug on a PE (polyethylene) sheet with a 2 cm square coating area. (2) A 3 cm square fabric or wrap film was attached to the part coated with the coating drug, and a weight was placed on it to make the fabric or wrap film and the coating drug adhere closely. (3) It was placed in an in-clothing environment (32 °C × 50% RH) and left standing for 2 hours. (4) After 2 hours, the fabric and the PE sheet were placed in separate screw tubes, 30 ml of hexane was added, and ultrasonic extraction was performed for 2 hours. (5) The liquid after ultrasonic extraction was analyzed by gas chromatography to quantify the drug components in the coating drug. (6) The ratio of the amount of the coating drug detected from the fabric or wrap film to the amount of the coating drug loaded was defined as the drug migration rate to the fabric.
[0050] <2-2. Evaluation of Air Permeability and Elongation Rate> The air permeability and elongation rate of each fabric and wrap film were measured in accordance with JIS L 1096.
[0051] <2-3. Evaluation of Drug Action Changes> The changes in drug action associated with the transfer of the drug to the fabric were evaluated according to the following procedure. The coating agent used was Hirumild, and the active ingredient was a heparin-like substance. (1) A 2 cm square coating agent application area was provided on the forearm, and each test fabric of 3 cm square was prepared. (2) The coating agent was applied to the application area between after bathing and before going to bed, and the test fabric was pasted on it and fixed with surgical tape. (3) Go to bed in that state and remove the fabric when getting up the next day (8-hour attachment). This was continued for one week. (4) On the 3rd and 7th days, the stratum corneum moisture content of each test site was measured using a stratum corneum moisture meter, and it was evaluated how much it had increased from the stratum corneum moisture content before the test.
[0052] [3. Evaluation Results] Figure 4 is a diagram showing the results of the evaluation of the drug-fabric transfer rate. As shown in Figure 4, the drug-fabric transfer rates of the fabrics of Examples 1 and 2 were equivalent to the drug-fabric transfer rate of the wrap film (Comparative Example 1), and were much lower than the drug-fabric transfer rates of the fabrics of Comparative Examples 2 and 3.
[0053] Figure 5 is a diagram showing the results of the air permeability evaluation. Referring to Figure 5, for the wrap film (Comparative Example 1), since there was no air permeability at all, the air permeability could not be measured. The air permeabilities of the fabrics of Examples 1 and 2 were much higher compared to the wrap film (Comparative Example 1).
[0054] Figure 6 is a diagram showing the results of the elongation and contraction rate evaluation. As shown in Figure 6, the elongation and contraction rates of the fabrics of Examples 1 and 2 were much higher compared to the wrap film (Comparative Example 1).
[0055] Figure 7 is a diagram showing the results of the evaluation of the change in drug action. Referring to Figure 7, the horizontal axis indicates the number of days elapsed since the start of the evaluation, and the vertical axis indicates the change rate of the stratum corneum moisture content. Transition L1 shows the transition of the change rate of the stratum corneum moisture content related to Example 1, and transition L2 shows the transition of the change rate of the stratum corneum moisture content related to Comparative Example 2. Transition L3 shows the transition of the change rate of the stratum corneum moisture content at the site where the applied drug is not applied. As shown in Figure 7, when the fabric of Example 1 was used, it was confirmed that the effect of the applied drug was sufficiently exhibited as compared with the case where the fabric of Comparative Example 2 was used.
Description of Signs
[0056] 10 Cover, 20 Water tank, 30 Nip roll, 40 Drying device, 100 Processing device, AF1 Affected part, AR1 Upper limb, HO1 Through hole, HU1 Patient, L1, L2, L3 Transition, LE1 Lower limb, LI1 Processing liquid.
Claims
1. A cover configured to cover an affected area of a patient having a skin disease, which is composed of a tubular knitted fabric, wherein the knitted fabric is subjected to water and oil repellent treatment, and the cover is configured to cover the affected area with a coating agent applied thereto.
2. The cover according to claim 1, wherein the affected area is a part of the upper or lower limb of the patient.
3. The cover according to claim 2, having a width of 4 cm or more and 27 cm or less when laid flat.
4. The basis weight of the woven fabric is 85 g / m 2 or more and 350 g / m 2 or less. The cover according to claim 3
5. The cover according to claim 4, which is seamless.
6. The cover according to claim 5, wherein the knitted fabric is composed of a heat-sealing elastic yarn and a yarn other than the heat-sealing elastic yarn and has a fraying prevention function.
7. The air permeability measured in accordance with JIS L 1096 is 25 cm 3 / cm 2 ·s or more, The cover according to any one of claims 1 to 6, having an elongation rate measured in accordance with JIS L 1096 of 50% or more.
Citation Information
Patent Citations
Textile products for patients with skin diseases
JP2012518099A