Boron neutron capture therapy device compatible with rotating target and fixed target and target replacement method

Abstract

To provide a boron neutron capture therapy device having compatibility between a rotary target and a fixed target, and a target replacement method.SOLUTION: A beam shaping assembly and a vacuum pipe 6, wherein the beam shaping assembly comprises a base 1, a reflector module 2 and a back reflector 4 are respectively arranged on two sides of the base 1, the base 1 is provided with an interchangeable cavity 3 capable of accommodating a rotary target module 7, when a rotary target is adopted, the rotary target module 7 is mounted in the interchangeable cavity 3, and the vacuum pipe 6 is connected to the rotary target module 7, and when a fixed target is adopted, the fixed target is detachably mounted on the vacuum pipe 6; The boron neutron capture therapy device can meet the configuration requirements of the fixed target and the rotating target at the same time, and facilitate the adjustment and update of the device.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present invention relates to the technical field of nuclear medicine radiotherapy, and more particularly to a boron neutron capture therapy device and target exchange method that are compatible with rotating targets and fixed targets. [Background technology]

[0002] Boron Neutron Capture Therapy (BNCT) is a dual therapy that combines targeted drugs with a neutron beam. Tumor cells enriched with boron drugs are irradiated with a neutron beam of a certain energy, and the cancer cells are destroyed by utilizing nuclear reactions limited to the tumor cells, achieving the effect of precisely destroying cancer cells without harming normal cells.

[0003] Neutron source targets are the components that generate neutrons and are primarily available as fixed or rotating targets. During initial design, the fixed and rotating targets are typically connected to the accelerator and the beam shaping device in different ways, so designers typically choose one of two options, but do not consider compatibility between the two, limiting future equipment upgrades. Next, compatibility between fixed and rotating targets must take into account the on-site layout and the impact on neutron performance and shielding after replacement. However, current equipment only allows for the installation of a single fixed or rotating target, making it impossible to achieve compatibility between the two, resulting in inconvenience during equipment upgrades. Summary of the Invention [Problem to be solved by the invention]

[0004] To overcome the above-mentioned shortcomings, the present invention provides a boron neutron capture therapy device and target replacement method that are compatible with rotating targets and fixed targets, which simultaneously meets the placement needs of fixed targets and rotating targets, does not require replacement or extensive disassembly of the beam shaping device, and is based on the equipment upgrade space while also improving the applicability of the therapy device. [Means for solving the problem]

[0005] In order to solve the above technical problems, the present invention adopts the following technical solutions. A boron neutron capture therapy device compatible with a rotating target and a fixed target, comprising a beam shaper and a vacuum line, wherein the beam shaper comprises a base, with a reflector module and a back reflector respectively mounted on both sides of the base, and a compatible cavity capable of accommodating the rotating target module is mounted on the base, and when a rotating target is employed, the rotating target module is attached to the compatible cavity and the vacuum line is connected to the rotating target module, and when a fixed target is employed, the fixed target is removably attached to the vacuum line.

[0006] The boron neutron capture therapy device is equipped with a base, and an interchangeable cavity is installed on the base to provide sufficient installation space for the rotating target. A modular rotating target module is also adopted, and the modular installation facilitates the replacement of the rotating target or fixed target. During replacement, only the rear reflector needs to be adjusted, eliminating the need to adjust the reflector module and other components, ensuring neutron performance after replacement.

[0007] The boron neutron capture therapy device of the present invention can simultaneously meet the needs of fixed and rotating target configurations, does not require replacement or extensive disassembly of the beam shaping device, and based on the upgrade space of the device, while also improving the applicability of the beam shaping device, can provide more neutron treatment parameters for different cancer cases. Because the rotating target and the fixed target can be interchangeably replaced, the device can meet different neutron flux needs according to developments at different times, and leaves enough space for repeated equipment upgrades and backup emergency situations.

[0008] The fixed target is removably attached to the vacuum line, and the vacuum line penetrates the back reflector to bring the fixed target close to the reflector module. When a rotating target is used, the fixed target is removed, and the rotating target module is installed in a compatible cavity, after which the vacuum line is connected to the rotating target module, and the same back reflector is used to avoid radiation damage caused by neutron recoil.

[0009] Preferably, mounting grooves are provided on the base and the reflector module, and the reflector module is fitted into the mounting groove for connection.

[0010] The reflector module is fitted into the mounting groove on the base, making it easy and secure to install. At the same time, it can shorten the distance between the moderator core and the target in the reflector module, reducing the possibility of proton scattering and helping to improve the flux of the neutron beam. In this case, the base also functions as a reflector.

[0011] Preferably, the base is provided with a through hole for the fixed target to pass through.

[0012] When a fixed target is employed, the vacuum line can be routed through the through-holes closer to the moderator core, helping to reduce the possibility of proton scattering and improve the flux of the neutron beam, with the base simultaneously functioning as a reflector.

[0013] Preferably, a decelerator core is installed in the reflector module, a countersunk groove is installed in the base, the through hole is installed at the bottom of the countersunk groove, and one end of the decelerator core is placed in the countersunk groove.

[0014] The countersunk groove is an optimized design that allows the moderator core to be closer to the target. The countersunk groove allows the moderator core to protrude from the reflector module and be closer to the target, and the base simultaneously functions as a reflector.

[0015] Preferably, the surface of the base is recessed to form a compatible cavity.

[0016] The surface of the base is depressed to form a compatible cavity, allowing the base to be completely separated on both the front and rear sides.

[0017] In another embodiment, the base is a frame-like structure, and the interior space of the frame-like structure base forms the compatible cavity.

[0018] The frame-like structural base allows the reflector module and back reflector to be closer together, shortening the distance between the moderator core and the target within the reflector module, reducing the possibility of proton scattering and helping to improve the flux of the neutron beam.

[0019] Preferably, a fixed seat is installed below the base, an adjustment pad is attached to the bottom of the base, and a plurality of elevating support columns are attached to the fixed seat, and the support columns support the adjustment pad.

[0020] The support posts support the adjustment pads, thereby realizing support for the base, and the support posts can be raised and lowered to adjust the height, facilitating position adjustment during the base installation process.

[0021] In another aspect, a fixed seat is installed below the base, a base pad and a reflector pad are installed on the fixed seat, a back reflector pad is installed on the base pad, a base support and a reflector support that can be raised and lowered are attached to the fixed seat, a back reflector support that can be raised and lowered is attached to the base pad, the base support supports the base pad, the reflector support supports the reflector pad, the back reflector support supports the back reflector pad, the base is attached to the base pad, the reflector module is attached to the reflector pad, and the back reflector is attached to the back reflector pad.

[0022] The height of the base is adjusted by moving the base support up and down, the mounting height of the reflector module is adjusted by moving the reflector support up and down, and the height position of the rear reflector is adjusted by moving the rear reflector support up and down. During the mounting process, the mounting is mounted by adjusting the height position to achieve collimation.

[0023] Preferably, the base is provided with a door curtain that can be moved and set up, and the movement of the door curtain can block the rotating target module or the fixed target in the neutron transmission direction.

[0024] When a boron neutron capture therapy device operates normally, the door curtain is installed offset from the target position, so it does not block the neutron transmission direction and does not block the target and reflector module. The moderator core in the reflector module needs to be replaced periodically. When the moderator core needs to be replaced on the treatment side, the door curtain moves to block the neutron transmission direction, separating the target and the neutron source, followed by the moderator core replacement. At this time, the separation of the door curtain allows workers to replace the moderator core under conditions that do not irradiate the target with gamma rays. After the moderator core replacement is complete, the door curtain returns to its original position, so that the door curtain and the target are no longer offset and no longer block the neutron transmission direction.

[0025] Preferably, a connecting groove is provided on the base, a slide rail is mounted in the connecting groove, a slide base is slidably mounted on the slide rail, the door curtain is fastened to the slide base and connected, and a slot is provided on the side wall of the connecting groove, and the door curtain is inserted into the slot to be connected.

[0026] The connecting groove on the base facilitates installation and mounting of the door curtain. The sliding base connected to the door curtain moves along the sliding rail, allowing the door curtain to slide smoothly and securely into the slot on the base.

[0027] Preferably, vias are placed in the door curtain, and movement of the door curtain separates the vias in and out of alignment with the neutron transmission direction.

[0028] When aligned with the via and the neutron transmission direction, the door curtain can occupy a relatively large space between the moderator core and the target, in which case the door curtain acts as a reflector and reduces the possibility of proton scattering. By moving the door curtain upward, the via is separated from the neutron transmission direction and the movement of the door curtain is blocked in the neutron transmission direction.

[0029] Preferably, the rotating target module includes a mounting housing and a rotating target located within the mounting housing, the rotating target including a target plate and a target, the target plate being connected to a spindle, and multiple targets being circumferentially arranged on the target plate to form an annular structure.

[0030] When the targets are rotated, the target platen and the spindle work together to constantly align several targets with the vacuum line, and the rotational motion increases the sweep size of the beam spot, thereby reducing the thermal power density of the targets and advantageously extending the service life of the targets.

[0031] A method for exchanging a rotating target and a fixed target in a boron neutron capture therapy device, the method realizing a target exchange operation of a boron neutron capture therapy device having interchangeable rotating targets and fixed targets, comprising: replacing the fixed target with a rotating target; and replacing the rotating target with a fixed target, wherein the replacing the fixed target with the rotating target comprises: The method includes step S1 of separating the vacuum line and the back reflector and transferring the back reflector; step S2 of installing the rotating target module in the compatible cavity and removing the fixed target on the vacuum line; step S3 of re-installing the back reflector in the compatible cavity so that the back reflector is close to the rotating target; and step S4 of passing the vacuum line through the back reflector and connecting the vacuum line to the rotating target to realize target replacement; Replacing a rotating target with a fixed target is The method includes step a) of separating the vacuum line from the rotating target and moving the vacuum line outward to retract it out of the back reflector, step b) of transferring the back reflector, step c) of transferring the rotating target module, step d) of reattaching the back reflector to the position of the interchangeable cavity, and step e) of attaching a fixed target to the vacuum line and inserting the vacuum line into the back reflector to achieve target replacement.

[0032] In the process of replacing a fixed target with a rotating target, only the steps of removing and installing the back reflector, removing the fixed target, and installing the rotating target module are required.In the process of replacing a rotating target with a fixed target, only the steps of removing and installing the back reflector, removing the rotating target module, and installing the rotating target are required.

[0033] In the process of target replacement between a fixed target and a rotating target, only the back reflector needs to be removed and installed, the rotating target module needs to be removed or installed, and the fixed target needs to be installed or removed, without the need to remove or install other modules and parts, making the operation convenient. [Effects of the Invention]

[0034] Compared with the prior art, the beneficial effects of the present invention are as follows: (1) The boron neutron capture therapy device can simultaneously meet the needs of fixed and rotating target configurations, does not require replacement or extensive disassembly of the beam shaping device, and based on the equipment upgrade space, while also improving the applicability of the beam shaping device. (2) A modular rotating target module is adopted, which can meet the installation requirements of both rotating and fixed targets. The modular installation makes it easy to replace the rotating or fixed target. The same back reflector is used, which avoids radiation damage caused by neutron recoil and at the same time improves neutron flux. In the case of replacement, only the back reflector needs to be adjusted, and there is no need to adjust the reflector module and other parts, so the neutron performance can be ensured after replacement. (3) When the moderator core needs to be replaced on the treatment side, the door curtain separates the target, separating the neutron source, allowing the moderator core to be replaced without removing the target.At this time, the gamma rays emitted from the target by separating the door curtain allow workers to replace the moderator core under conditions where the target is not irradiated with radiation. (4) The height of the base can be adjusted during the installation process, making it easy to fit and install. (5) Even though a base is installed in the boron neutron capture therapy device, the installation of the through-hole allows the moderator core to be as close as possible to the target, reducing the possibility of proton scattering and helping to improve the flux of the neutron beam. [Brief explanation of the drawings]

[0035] [Figure 1] 1 is a structural schematic diagram of embodiment 1 of the present invention. [Figure 2] FIG. 1 is a cross-sectional view of a first embodiment of the present invention. [Figure 3] FIG. 1 is a cross-sectional view of a second embodiment of the present invention. [Figure 4] FIG. 1 is a structural schematic diagram of a third embodiment of the present invention. [Figure 5] FIG. 10 is a cross-sectional view of a third embodiment of the present invention. [Figure 6] FIG. 10 is a cross-sectional view of a fourth embodiment of the present invention. [Figure 7] FIG. 10 is a cross-sectional view of a fifth embodiment of the present invention. [Figure 8] FIG. 10 is a cross-sectional view of a sixth embodiment of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0036] The technical solution of the present invention will be further specifically described below using specific embodiments with reference to the drawings. (Embodiment 1) A boron neutron capture therapy device compatible with a rotating target and a fixed target (see attached drawings 1 and 2) includes a beam shaper and a vacuum line 6, the beam shaper includes a base 1, a reflector module 2 and a back reflector 4 are respectively installed on the front and rear sides of the base 1, a moderator core is installed within the reflector module 2, and a compatible cavity 3 for a rotating target module 7 that can be housed in the base 1 is installed. When a rotating target is used, the rotating target module 7 is attached to the compatible cavity 3 and the vacuum line 6 is connected to the rotating target module 7, and when a fixed target is used, the fixed target is detachably attached to the vacuum line 6.

[0037] A reflector module 2 is mounted on the front side of the base 1, and a compatible cavity 3 is installed on the rear side of the base 1, with the width of the rotating target module 7 matching the width of the compatible cavity 3. The width of the back reflector 4 may or may not match the width of the compatible cavity 3. If the width of the back reflector 4 matches the width of the compatible cavity 3, the front side of the back reflector 4 can be fitted and mounted within the compatible cavity. If the width of the back reflector 4 and the width of the compatible cavity 3 cannot match and the beam shaper uses a fixed target, an auxiliary block is mounted within the compatible cavity, with both sides of the auxiliary block abutting against the bottom surface of the compatible cavity 3 and the front side of the back reflector 4, respectively.

[0038] By selecting lead as the main material for the base 1, it is possible to reflect recoil neutrons at the same time as the back reflector 4, improving the neutron flux. Since the generated neutrons are present in all directions, it is necessary to position the back reflector 4 in the opposite direction from the neutron beam exit to reduce the leakage of recoil neutrons and improve the neutron flux. The back reflector 4 is generally made of lead, but it can also be replaced with BeO, polyethylene, etc. The base 1, which is made of lead, can be part of the back reflector 4, and can be used to attach the target body and reflect neutrons.

[0039] A via is installed in the back reflector 4, and a vacuum line 6 is inserted into the via and movable along the via, forming a cavity in the vacuum line 6 to form a proton beam channel 5. When a rotating target is used, a rotating target module 7 is detachably installed in the compatible cavity 3, a separation cavity 8 is installed in the rotating target module 7, and the rotating target is installed in the separation cavity 8. An insertion hole 9 is installed in the rotating target module 7 corresponding to the vacuum line 6, and the end of the vacuum line 6 can be detachably connected to the edge of the insertion hole 9. When a fixed target is used, the fixed target is detachably installed in the vacuum line 6. A mounting groove 10 is installed in the base 1 and the reflector module 2 corresponding to the mounting groove 10, and the reflector module 2 is fitted and connected to the mounting groove 10. A through hole 14 is installed in the base 1 for the fixed target to pass through, and the through hole 14 communicates between the compatible cavity 3 and the mounting groove 10. When the fixed target is attached, the fixed target protrudes into the through hole 14, shortening the distance between the target and the moderator core.

[0040] A fixed seat 20 is installed below the base 1, an adjustment pad 21 is attached to the bottom of the base 1, and a plurality of support columns 22 that can be raised and lowered are attached to the fixed seat 20, and the support columns 22 support the adjustment pad 21.

[0041] The upper surface of the adjusting pad 21 and the lower surface of the base 1 both have a stepped structure, which facilitates accurate positioning during the process of fitting and connecting the lower surface of the base 1 and the upper surface of the adjusting pad 21. The support post 22 is a support screw, the nut end of which protrudes from the adjusting pad 21 and is threaded into the fixing seat 20, and the support height can be finely adjusted by rotating the support screw.

[0042] The surface of the base 1 is sunken to form a compatible cavity 3, and the base 1 can be completely separated into front and rear sides. The base 1 is completely closed except for the through-hole 14.

[0043] A movable door curtain 11 is attached to the base 1, and movement of the door curtain 11 can block the rotating target module 7 or the fixed target in the direction of neutron transmission. Targets 12 are installed on both the rotating target and the fixed target, and the door curtain 11 moves between the target 12 and the moderator core, in which case the door curtain can block the target 12. Vias 13 are installed in the door curtain 11, and the vias 13 are installed corresponding to the target 12. As the door curtain 11 moves, the vias 13 and the target 12 are aligned and separated. When the vias 13 on the door curtain 11 are aligned and separated from the target 12, the door curtain 11 blocks the target 12. When the door curtain moves upward, the vias 13 move upward and misalign with the through-hole 14, and the lower part of the vias on the door curtain covers the through-hole 14, thereby blocking the target 12.

[0044] The door curtain 11 is attached to the front side of the base 1, a connecting groove 15 is formed in the front side of the base 1, a slide rail 16 is installed in the connecting groove 15, a slide base 17 is slidably attached to the slide rail 16, and the door curtain 11 is fastened to and connected to the slide base 17. A slot 18 is formed in the side wall of the connecting groove 15, and the door curtain 11 is inserted into the slot 18 to be connected. The slide base 17 is driven by a driving mechanism, which can be a piston cylinder or a driving motor. If a piston cylinder is used, the piston cylinder telescopic rod is connected to the slide base 17. If a driving motor is used, the output shaft of the driving motor is connected to a screw, and the slide base 17 is threaded onto the screw. The driving motor rotates the screw to move the slide base 17. A closing block 19 is attached to the open end of the connecting groove 15.

[0045] The rotating target module 7 includes a mounting housing and a rotating target located within the mounting housing, a cavity within the mounting housing forming a separation cavity 8, the rotating target including a target plate 23 and targets 12, the target plate 23 connected to a main shaft 24, and multiple targets 12 circumferentially mounted on the target plate 23 to form an annular structure.

[0046] The boron neutron capture therapy device is installed with a base 1, and an interchangeable cavity 3 is installed in the base 1 to provide sufficient installation space for the rotating target module 7. Furthermore, a modular rotating target module 7 is adopted, and the modular installation makes it easy to replace the rotating target or fixed target. During replacement, only the back reflector 4 needs to be adjusted, and there is no need to adjust the reflector module 2 or other components, ensuring neutron performance after replacement.

[0047] The boron neutron capture therapy device of this patent application simultaneously meets the needs of fixed and rotating target placement, does not require replacement or extensive disassembly of the beam shaping device, and based on the upgrade space of the equipment, also improves the applicability of the beam shaping device. Because the rotating target and the fixed target can be interchangeably replaced, the equipment can meet different neutron flux needs according to the development of different periods, and leaves enough space for repeated equipment upgrades and backup emergency situations.

[0048] The fixed target is removably attached to the vacuum line 6, which penetrates the back reflector 4 to bring the fixed target close to the moderator core. When a rotating target is used, the fixed target is removed and the rotating target module 7 is installed in the compatible cavity 3, after which the vacuum line 6 is connected to the rotating target module 7, and the same back reflector 4 is used to avoid radiation damage caused by neutron recoil.

[0049] When the moderator core needs to be replaced on the treatment side, the door curtain 11 separates the target and the neutron source, allowing the moderator core to be replaced without removing the target 12. At this time, the separation of the door curtain 11 allows workers to replace the moderator core under conditions where the target is not irradiated with gamma rays. The height of the base 1 can be adjusted during the installation process, which also makes installation easier. Although the base 1 is installed in the boron neutron capture therapy device, the installation of the through-hole 14 allows the moderator core to be as close as possible to the target 12, reducing the possibility of proton scattering and helping to improve the neutron beam flux.

[0050] A method for exchanging a rotating target and a fixed target in a boron neutron capture therapy device, the method realizing a target exchange operation of a boron neutron capture therapy device having interchangeable rotating targets and fixed targets, comprising: replacing the fixed target with a rotating target; and replacing the rotating target with a fixed target, wherein the replacing the fixed target with the rotating target comprises: The method includes step S1 of separating the vacuum line 6 installed on the back reflector 4 from the back reflector 4, transporting the back reflector 4, and during operation, directly moving the vacuum line 6 backward to exit the back reflector 4; step S2 of installing the rotating target module 7 in the interchangeable cavity 3 and removing the fixed target on the vacuum line 6; step S3 of re-installing the back reflector 4 in the interchangeable cavity 3 so that the back reflector 4 is close to the rotating target; and step S4 of passing the vacuum line 6 through the back reflector 4 and connecting the vacuum line 6 to the rotating target to realize target replacement. Replacing a rotating target with a fixed target is The method includes step a) of separating the vacuum line 6 installed on the back reflector 4 from the rotating target and moving the vacuum line 6 outward to retract it out of the back reflector 4, step b) of transferring the back reflector 4, step c) of transferring the rotating target module 7, step d) of reattaching the back reflector 4 to the position of the interchangeable cavity 3, and step e) of attaching a fixed target to the vacuum line 6 and inserting the vacuum line into the back reflector 4 until the fixed target enters the through-hole 14 on the base, thereby realizing target replacement.

[0051] In the process of replacing a fixed target with a rotating target, only the steps of removing and attaching the back reflector 4, removing the fixed target, and attaching the rotating target module 7 are required. In the process of replacing a rotating target with a fixed target, only the steps of removing and attaching the back reflector 4, removing the rotating target module 7, and attaching the fixed target are required. In the process of exchanging a fixed target and a rotating target, only the steps of removing and attaching the back reflector 4, removing or attaching the rotating target module 7, and attaching or removing the fixed target are required, and there is no need to attach or detach other modules and parts, making the operation convenient.

[0052] (Embodiment 2) This embodiment is a boron neutron capture therapy device (see attached drawing 3) compatible with a rotating target and a fixed target. Its structure is similar to that of embodiment 1, with the main difference being that in this embodiment, a door curtain 11 is attached to the rear side of a base 1, and a connecting groove 15 is provided at the bottom of a compatible cavity 3 at the rear of the base 1, with the width of the connecting groove 15 being smaller than that of the compatible cavity 3. A slide rail 16 is attached in the connecting groove 15, and a slide base 17 is slidably attached to the slide rail 16. The door curtain 11 is fastened to and connected to the slide base 17, and a slot 18 is provided in the lower side wall of the connecting groove 15, and the door curtain 11 is inserted into and connected to the slot 18. The slide base 17 is driven by a driving mechanism, which may be a piston cylinder or a driving motor. When a piston cylinder is used, a piston cylinder telescopic rod is connected to the slide base 17. When a drive motor is used, the drive motor output shaft is connected to a screw, the slide base 17 is threaded onto the screw, and the drive motor rotates the screw, thereby realizing the movement of the slide base 17.

[0053] A decelerator core is installed in the reflector module 2, a countersunk groove 52 is installed in the base 1, the countersunk groove 52 is installed in the bottom surface of the mounting groove 10, a through hole 14 is installed in the bottom of the countersunk groove 52, and one end of the decelerator core is placed in the countersunk groove 52. The lower part of the door curtain 11 is placed in the countersunk groove 52. The other structures are the same as those in the first embodiment.

[0054] The countersunk groove is an optimized design that allows the moderator core to be closer to the target 12, and by installing the countersunk groove 52, the moderator core can be protruded from the reflector module 2 and brought closer to the target 12, and the base 1 simultaneously functions as a reflector.

[0055] (Embodiment 3) A boron neutron capture therapy device (see attached drawings 4 and 5) compatible with rotating targets and fixed targets, the structure of which is similar to that of embodiment 1, with the main difference being that in this embodiment, a fixed seat 20 is installed below a base 1, a base pad 53 and a reflector pad 54 are installed on the fixed seat 20, a back reflector pad 55 is installed on the base pad 53, a base support 56 and a reflector support 57 that can be raised and lowered are attached to the fixed seat 20, a back reflector support 58 that can be raised and lowered is attached to the base pad 53, the base support 56 supports the base pad 53, the reflector support 57 supports the reflector pad 54, the back reflector support 58 supports the back reflector pad 55, the base 1 is attached to the base pad 53, the reflector module 2 is attached to the reflector pad 54, and the back reflector 4 is attached to the back reflector pad 55. The base support 56, the reflector support 57 and the rear reflector support 58 are all support screws, and the support screws are threaded to adjust the height, with the nut end of the support screw at the top.

[0056] The height of the base 1 is adjusted by moving the base support 56 up and down, the mounting height of the reflector module 2 is adjusted by moving the reflector support 57 up and down, and the height position of the back reflector 4 is adjusted by moving the back reflector support 58 up and down. During the mounting process, adjusting the height position assists mounting and achieves collimation.

[0057] A connecting groove 15 is formed at the bottom of the compatible cavity 3 at the rear of the base 1, and its width is smaller than that of the compatible cavity 3. A slide rail 16 is installed in the connecting groove 15, a slide base 17 is slidably installed on the slide rail 16, and the door curtain 11 is fastened to and connected to the slide base 17. A slot 18 is formed in the side wall of the connecting groove 15, and the door curtain 11 is inserted into and connected to the slot 18. The slide base 17 is driven by a driving mechanism, which can be a piston cylinder or a driving motor. If a piston cylinder is used, the piston cylinder telescopic rod is connected to the slide base 17. If a driving motor is used, the driving motor output shaft is connected to a screw, and the slide base 17 is screwed onto the screw. The driving motor rotates the screw to move the slide base 17. A decelerator core is installed inside the reflector module 2, a countersunk groove 52 is installed in the base 1, a through hole 14 is installed at the bottom of the countersunk groove 52, and one end of the decelerator core is placed in the countersunk groove 52. The countersunk groove 52 is placed at the bottom of the mounting groove 10. The lower part of the door curtain 11 is placed in the countersunk groove 52. The other structures are the same as those in the first embodiment.

[0058] (Embodiment 4) A boron neutron capture therapy device (see attached drawing 6) compatible with rotating targets and fixed targets, its structure is similar to that of embodiment 1, with the main difference being that in this embodiment, a fixed seat 20 is installed below a base 1, a base pad 53 and a reflector pad 54 are installed on the fixed seat 20, a back reflector pad 55 is installed on the base pad 53, a base support 56 and a reflector support 57 that can be raised and lowered are attached to the fixed seat 20, a back reflector support 58 that can be raised and lowered is attached to the base pad 53, the base support 56 supports the base pad 53, the reflector support 57 supports the reflector pad 54, the back reflector support 58 supports the back reflector pad 55, the base 1 is attached to the base pad 53, the reflector module 2 is attached to the reflector pad 54, and the back reflector 4 is attached to the back reflector pad 55. The base support 56, the reflector support 57 and the rear reflector support 58 are all support screws, and the support screws are threaded to adjust the height, with the nut end of the support screw at the top.

[0059] The height of the base 1 is adjusted by moving the base support 56 up and down, the mounting height of the reflector module 2 is adjusted by moving the reflector support 57 up and down, and the height position of the back reflector 4 is adjusted by moving the back reflector support 58 up and down. During the mounting process, adjusting the height position assists mounting and achieves collimation. The other structures are the same as those in the first embodiment.

[0060] (Embodiment 5) This boron neutron capture therapy device (see attached drawing 7) is compatible with both rotating and fixed targets. Its structure is similar to that of embodiment 1 and embodiment 3, with the main difference being that in this embodiment, the base 1 has a frame-like structure, and the internal space of the frame-like structure base 1 forms an interchangeable cavity 3. A shield block is attached above the reflector module 2 in the interchangeable cavity 3. When a fixed target is used, the reflector module 2 and the back reflector 4 are directly bonded together, with the fixed target being close to the moderator core and the base being placed around the reflector module 2 and the back reflector 4. When a rotating target is used, the front and rear sides of the rotating target module 7 are bonded to the reflector module 2 and the back reflector 4, respectively. In this embodiment, the door curtain 11 is not installed, and the mounting groove 10, countersunk groove 52, and through-hole 14 are not installed in the base 1. The other structures are the same as those of embodiment 1 or embodiment 3.

[0061] A method for exchanging a rotating target and a fixed target in a boron neutron capture therapy device, the method realizing a target exchange operation of a boron neutron capture therapy device having interchangeable rotating targets and fixed targets, comprising: replacing the fixed target with a rotating target; and replacing the rotating target with a fixed target, wherein the replacing the fixed target with the rotating target comprises: The method includes the following steps: step S1: separating the vacuum line 6 installed on the back reflector 4 from the back reflector 4, transporting the back reflector 4, and during operation, directly moving the vacuum line 6 backward to exit the back reflector 4; step S2: installing the rotating target module 7 in the interchangeable cavity 3 and removing the fixed target on the vacuum line 6; step S3: re-installing the back reflector 4 in the interchangeable cavity 3 so that the back reflector 4 is close to the rotating target, and joining and connecting the reflector module 2, the rotating target module 7 and the back reflector 4; step S4: inserting the vacuum line 6 into the back reflector 4 and connecting the vacuum line 6 to the rotating target to realize target replacement. Replacing a rotating target with a fixed target is The method includes step a) of separating the vacuum line 6 installed on the back reflector 4 from the rotating target and moving the vacuum line 6 outward to retract it out of the back reflector 4; step b) of transporting the back reflector 4; step c) of transporting the rotating target module 7; step d) of reattaching the back reflector 4 to the interchangeable cavity 3 and joining and connecting the reflector module 2 and the back reflector 4; and step e) of attaching a fixed target to the vacuum line 6 and inserting the vacuum line into the back reflector 4 until the fixed target protrudes into the rear side of the reflector module, thereby realizing target replacement.

[0062] (Embodiment 6) A boron neutron capture therapy device (see attached drawing 8) compatible with rotating targets and fixed targets, the structure of which is similar to that of embodiment 1 or embodiment 4, with the main difference being that in this embodiment, a moderator core is installed in a reflector module 2, a countersunk groove is installed in a base 1, a through hole 14 is installed at the bottom of the countersunk groove 52, and one end of the moderator core is placed in the countersunk groove 52. The countersunk groove 52 is placed at the bottom of a mounting groove 10. The lower part of a door curtain 11 is placed in the countersunk groove 52. The other structures are the same as those of embodiment 1 or embodiment 4.

[0063] The countersunk groove is an optimized design that allows the moderator core to be closer to the target 12, and by installing the countersunk groove 52, the moderator core can be protruded from the reflector module 2 and brought closer to the target 12, and the base 1 simultaneously functions as a reflector.

[0064] The above-described embodiments are merely preferred aspects of the present invention, and do not impose any formal limitations on the present invention. There may be other modifications and variations within the scope of the technical solutions set forth in the claims.

[0065] (Addendum) (Appendix 1) A boron neutron capture therapy device compatible with a rotating target and a fixed target, comprising a beam shaper and a vacuum line, the beam shaper comprising a base, a reflector module and a back reflector respectively installed on both sides of the base, a compatible cavity capable of accommodating the rotating target module installed on the base, when the rotating target is adopted, the rotating target module is attached to the compatible cavity and the vacuum line is connected to the rotating target module, and when the fixed target is adopted, the fixed target is detachably attached to the vacuum line; A boron neutron capture therapy device having compatibility between a rotating target and a fixed target, characterized in that:

[0066] (Appendix 2) The mounting grooves are correspondingly installed on the base and the reflector module, and the reflector module is fitted into the mounting groove and connected; 2. A boron neutron capture therapy device having compatibility between a rotating target and a fixed target as described in appendix 1.

[0067] (Appendix 3) The base is provided with a through hole through which the fixed target passes. 2. A boron neutron capture therapy device having compatibility between a rotating target and a fixed target as described in appendix 1.

[0068] (Appendix 4) a decelerator core is installed in the reflector module, a counterbore groove is installed in the base, a through hole is installed at the bottom of the counterbore groove, and one end of the decelerator core is placed in the counterbore groove; 4. A boron neutron capture therapy device having compatibility between a rotating target and a fixed target as described in appendix 3.

[0069] (Appendix 5) The surface of the base is depressed to form a compatible cavity; 2. A boron neutron capture therapy device having compatibility between a rotating target and a fixed target as described in appendix 1.

[0070] (Appendix 6) The base has a frame-like structure, and the internal space of the frame-like structure base forms an interchangeable cavity; 2. A boron neutron capture therapy device having compatibility between a rotating target and a fixed target as described in appendix 1.

[0071] (Appendix 7) A fixed seat is installed under the base, an adjustment pad is attached to the bottom of the base, and a plurality of elevating support columns are attached to the fixed seat, and the support columns support the adjustment pad; 7. A boron neutron capture therapy device having compatibility between a rotating target and a fixed target according to any one of appendices 1 to 6.

[0072] (Appendix 8) a fixed seat is installed below the base, a base pad and a reflector pad are installed on the fixed seat, a rear reflector pad is installed on the base pad, a base support and a reflector support that can be raised and lowered are attached to the fixed seat, a rear reflector support that can be raised and lowered is attached to the base pad, the base support supports the base pad, the reflector support supports the reflector pad, the rear reflector support supports the rear reflector pad, the base is attached to the base pad, the reflector module is attached to the reflector pad, and the rear reflector is attached to the rear reflector pad; 7. A boron neutron capture therapy device having compatibility between a rotating target and a fixed target according to any one of appendices 1 to 6.

[0073] (Appendix 9) A movable door curtain is attached to the base, and the door curtain can block the rotating target module or the fixed target in the neutron transmission direction by moving. 6. A boron neutron capture therapy device having compatibility between a rotating target and a fixed target according to any one of appendices 1 to 5.

[0074] (Appendix 10) A connecting groove is provided on the base, a slide rail is installed in the connecting groove, a slide base is slidably installed on the slide rail, the door curtain is fastened and connected to the slide base, and a slot is provided on the side wall of the connecting groove, and the door curtain is inserted into the slot to be connected. 10. A boron neutron capture therapy device having compatibility between a rotating target and a fixed target as described in appendix 9.

[0075] (Appendix 11) Vias are installed in the door curtain, and movement of the door curtain aligns or dealigns the direction of neutron transmission with the vias. 10. A boron neutron capture therapy device having compatibility between a rotating target and a fixed target as described in appendix 9.

[0076] (Appendix 12) The rotating target module includes a mounting housing and a rotating target located within the mounting housing, the rotating target including a target platen and targets, the target platen being connected to the spindle, and a plurality of targets being circumferentially arranged on the target platen to form an annular structure; 2. A boron neutron capture therapy device having compatibility between a rotating target and a fixed target as described in appendix 1.

[0077] (Appendix 13) A target exchange method for a rotating target and a fixed target of a boron neutron capture therapy device, the method including: realizing a target exchange operation of a boron neutron capture therapy device having compatibility between a rotating target and a fixed target according to any one of Supplementary Notes 1 to 12; and replacing the fixed target with a rotating target; and replacing the rotating target with a fixed target, wherein the replacing the fixed target with the rotating target is: The method includes step S1 of separating the vacuum line and the back reflector and transferring the back reflector; step S2 of installing the rotating target module in the compatible cavity and removing the fixed target on the vacuum line; step S3 of re-installing the back reflector in the compatible cavity so that the back reflector is close to the rotating target; and step S4 of passing the vacuum line through the back reflector and connecting the vacuum line to the rotating target to realize target replacement; Replacing a rotating target with a fixed target is The method includes: step a) separating the vacuum line from the rotating target and moving the vacuum line outward to retract outside the back reflector; step b) transferring the back reflector; step c) transferring the rotating target module; step d) reattaching the back reflector to the interchangeable cavity; and step e) attaching a fixed target to the vacuum line and inserting the vacuum line into the back reflector to achieve target replacement. A method for exchanging a rotating target with a fixed target. [Explanation of symbols]

[0078] 1 base 2 Reflector Module 3 Compatible Cavities 4 Back reflector 5. Proton Beam Channel 6 Vacuum line 7 Rotating Target Module 8 Separation Cavity 9 Insertion hole 10 Mounting groove 11 Door Curtain 12 Target 13 Beer 14 Through holes 15 Connection groove 16 Slide rail 17 Slide Base 18 slots 19 Closed Block 20 Fixed seat 21 Adjustment Pad 22 Posts 23 Target Board 24 Spindle 52 Counterbore 53 Base pad 54 Reflector Pad 55 Rear reflector pad 56 Base support 57 Reflector strut 58 Rear reflector strut 59 Shield Block

Claims

1. A boron neutron capture therapy device compatible with a rotating target and a fixed target, comprising a beam shaper and a vacuum line, the beam shaper comprising a base, a reflector module and a back reflector respectively installed on both sides of the base, a compatible cavity capable of accommodating the rotating target module installed on the base, when the rotating target is adopted, the rotating target module is attached to the compatible cavity and the vacuum line is connected to the rotating target module, and when the fixed target is adopted, the fixed target is detachably attached to the vacuum line; A boron neutron capture therapy device having compatibility between a rotating target and a fixed target, characterized in that:

2. The mounting grooves are correspondingly installed on the base and the reflector module, and the reflector module is fitted into the mounting groove and connected; 2. The boron neutron capture therapy device according to claim 1, wherein the boron neutron capture therapy device is compatible with both rotating and fixed targets.

3. The base is provided with a through hole through which the fixed target passes.

2. The boron neutron capture therapy device according to claim 1, wherein the boron neutron capture therapy device is compatible with both rotating and fixed targets.

4. a decelerator core is installed in the reflector module, a counterbore groove is installed in the base, a through hole is installed at the bottom of the counterbore groove, and one end of the decelerator core is placed in the counterbore groove; 4. The boron neutron capture therapy device according to claim 3, wherein the boron neutron capture therapy device is compatible with both rotating targets and fixed targets.

5. The surface of the base is depressed to form a compatible cavity; 2. The boron neutron capture therapy device according to claim 1, wherein the boron neutron capture therapy device is compatible with both rotating and fixed targets.

6. The base has a frame-like structure, and the internal space of the frame-like structure base forms an interchangeable cavity; 2. The boron neutron capture therapy device according to claim 1, wherein the boron neutron capture therapy device is compatible with both rotating and fixed targets.

7. A fixed seat is installed under the base, an adjustment pad is attached to the bottom of the base, and a plurality of elevating support columns are attached to the fixed seat, and the support columns support the adjustment pad; 7. A boron neutron capture therapy device having compatibility between the rotating target and the fixed target according to claim 1.

8. a fixed seat is installed below the base, a base pad and a reflector pad are installed on the fixed seat, a rear reflector pad is installed on the base pad, a base support and a reflector support that can be raised and lowered are attached to the fixed seat, a rear reflector support that can be raised and lowered is attached to the base pad, the base support supports the base pad, the reflector support supports the reflector pad, the rear reflector support supports the rear reflector pad, the base is attached to the base pad, the reflector module is attached to the reflector pad, and the rear reflector is attached to the rear reflector pad; 7. A boron neutron capture therapy device having compatibility between the rotating target and the fixed target according to claim 1.

9. A movable door curtain is attached to the base, and the door curtain can block the rotating target module or the fixed target in the neutron transmission direction by moving.

6. A boron neutron capture therapy device having compatibility between the rotating target and the fixed target according to claim 1.

10. A connecting groove is provided on the base, a slide rail is installed in the connecting groove, a slide base is slidably installed on the slide rail, the door curtain is fastened and connected to the slide base, and a slot is provided on the side wall of the connecting groove, and the door curtain is inserted into the slot to be connected.

10. The rotating target / fixed target compatible boron neutron capture therapy device of claim 9.

11. Vias are installed in the door curtain, and movement of the door curtain aligns or dealigns the direction of neutron transmission with the vias.

10. The rotating target / fixed target compatible boron neutron capture therapy device of claim 9.

12. The rotating target module includes a mounting housing and a rotating target located within the mounting housing, the rotating target including a target platen and targets, the target platen being connected to the spindle, and a plurality of targets being circumferentially arranged on the target platen to form an annular structure; 2. The boron neutron capture therapy device according to claim 1, wherein the boron neutron capture therapy device is compatible with both rotating and fixed targets.

13. A method for exchanging a rotating target and a fixed target in a boron neutron capture therapy device, the method realizing a target exchange operation of a boron neutron capture therapy device having compatibility between the rotating target and the fixed target according to any one of claims 1 to 12, and including replacing the fixed target with the rotating target, and replacing the rotating target with the fixed target, wherein the replacing the fixed target with the rotating target is: The method includes: step S1 of separating the vacuum line and the back reflector and transferring the back reflector; step S2 of attaching the rotating target module to the compatible cavity and removing the fixed target on the vacuum line; step S3 of reattaching the back reflector to the compatible cavity so that the back reflector is close to the rotating target; and step S4 of passing the vacuum line through the back reflector and connecting the vacuum line to the rotating target to realize target exchange; Replacing a rotating target with a fixed target is The method includes: step a) separating the vacuum line from the rotating target and moving the vacuum line outward to retract it out of the back reflector; step b) transferring the back reflector; step c) transferring the rotating target module; step d) reattaching the back reflector to the interchangeable cavity; and step e) attaching a fixed target to the vacuum line and inserting the vacuum line into the back reflector to achieve target exchange. A method for exchanging a rotating target with a fixed target.

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