Drug solution administration device

Abstract

To provide a liquid medicine administration instrument capable of preventing the leakage of a liquid medicine and securing liquid tightness between a sealing member and a liquid medicine discharge part when opening a liquid medicine passage by puncturing the sealing member provided in the liquid medicine discharge part with a connection needle.SOLUTION: The drug solution administration device 10 includes a drug solution container 100, a closing body 200, and a connector 300. The closing body 200 has a sealing member 210 and a fixing member 250. An opening 266 is formed in the fixing member 250. The connector 300 has a connecting needle 340. When the connector 300 is attached to the closing body 200, the connecting needle 340 pierces the sealing member 210 through the opening 266. The drug solution administration device 10 includes a first engaging portion 126 provided outside the drug solution discharge portion 104 and a second engaging portion 314 provided in the connector 300. The first engaging portion 126 and the second engaging portion 314 engage with each other when the connector 300 is attached to the closing body 200.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present invention relates to a drug solution administration device including a drug solution container and a connector. [Background technology]

[0002] Conventionally, there are known drug solution administration devices that are attached to a patient's body to administer a drug solution. For example, Patent Document 1 discloses a drug solution administration device that includes a housing and a syringe and a plunger housed inside the housing. This drug solution administration device is provided with a hub luer lock that covers the drug solution discharge portion of the syringe. A cap is attached to the hub luer lock.

[0003] The drug solution outlet of the drug solution discharge part is blocked by a rubber packing. A through hole is formed in the rubber packing. Meanwhile, the cap has a blocking plug part. The blocking plug part is provided with an injection needle that is to be inserted into the patient's body. The blocking plug part is fitted into the through hole. This fitting positions the base end of the injection needle at the drug solution outlet. The tip end of the injection needle is exposed from the blocking plug part and is to be inserted into the patient's body.

[0004] The plunger moves within the syringe toward the injection needle, and the liquid medicine within the syringe is pushed by the moving plunger and administered to the patient through the injection needle. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] Japanese Patent Application Laid-Open No. 2010-131064 Summary of the Invention [Problem to be solved by the invention]

[0006] In a drug administration device, in order to increase the pressure resistance of the drug solution discharge portion of the syringe, it is conceivable to provide an adapter around the outer periphery of the drug solution discharge portion and connect a tube with a connector to the adapter by screwing. However, when using a screw, the threads can gradually loosen while the drug administration device is being used. For this reason, the patient must periodically check the tightness of the connector and adapter. Such periodic checking is cumbersome.

[0007] To avoid this, it is conceivable to provide a sealing member made of an elastic material at the drug solution discharge portion and pierce the sealing member with a connecting needle. When a sealing member is used, it is desirable to ensure sufficient liquid-tightness between the sealing member and the drug solution discharge portion to prevent leakage of the drug solution.

[0008] The present invention aims to solve the above-mentioned problems. [Means for solving the problem]

[0009] (1) According to one embodiment of the present invention, there is provided a drug solution administration device comprising a drug solution container, a closure disposed at the tip of the drug solution container, and a connector attached to the closure, wherein the drug solution container has a drug solution storage section for storing the drug solution, a cylindrical drug solution discharge section provided at the tip of the drug solution container, and a drug solution discharge hole formed in the drug solution discharge section for discharging the drug solution, and the closure has a sealing member made of an elastic body and for liquid-tightly sealing the drug solution discharge hole, a fixing member for positioning and fixing the sealing member to the drug solution container, and an opening formed in the fixing member through which a part of the sealing member is exposed, and the sealing member is attached to the fixing member. a connecting needle that passes through the opening of the fixing member and pierces the sealing member when the connector is attached to the occluder, a needle hub that holds the connecting needle, and a pressing portion that presses the fixing member toward the drug solution discharge portion when the connector is attached to the occluder; and the drug solution administration device has a first engaging portion provided on the outside of the drug solution discharge portion and a second engaging portion provided on the connector, and the first engaging portion and the second engaging portion engage with each other when the connector is attached to the occluder.

[0010] When the connector is attached to the closure, the pressing portion of the connector presses the sealing member of the closure toward the drug solution discharge portion. In this state, a first engagement portion provided on the outside of the drug solution discharge portion engages with a second engagement portion provided on the connector. Based on this engagement, the pressing portion maintains the state in which the sealing member is pressed toward the drug solution discharge portion. This improves the liquid-tightness between the drug solution discharge portion and the sealing member. Furthermore, the liquid-tightness is maintained even when pressure is applied to the drug solution in the drug solution container to administer it to a patient.

[0011] (2) In the above item (1), it is preferable that the drug solution administration device includes a first extension portion that extends in a first direction from the base end of the drug solution discharge portion toward the tip end and includes the first engagement portion, and a second extension portion that extends in a second direction from the tip end of the connector toward the base end and includes the second engagement portion.

[0012] The presence of the first extension portion allows the first engagement portion to be positioned at a desired position, and similarly, the presence of the second extension portion allows the second engagement portion to be positioned at a desired position.

[0013] (3) In the above item (1) or (2), it is preferable that the drug solution administration device has a guiding part and a guided part. In this configuration, the guiding part and the guided part come into contact with each other while the connector is being attached to the closure, and the guided part is guided by the guiding part.

[0014] The guiding portion and the guided portion come into contact with each other, thereby preventing the connecting needle from shifting in position relative to the sealing member. In this state, the connecting needle can be moved toward the sealing member.

[0015] (4) In the above item (1), the drug solution administration device may include a first extending portion that extends in a first direction from the base end toward the tip of the drug solution discharge portion and includes the first engaging portion, and a second extending portion that extends in a second direction from the tip toward the base end of the connector and includes the second engaging portion, wherein the first extending portion includes a guiding portion and the second extending portion includes a guided portion. Also in this configuration, the guiding portion and the guided portion abut against each other during attachment of the connector to the closure, and the guided portion is guided by the guiding portion.

[0016] The guiding portion and the guided portion abut against each other, thereby preventing the connecting needle from shifting in position relative to the sealing member. In this state, the connecting needle can be moved toward the sealing member. Furthermore, with this configuration, the first extending portion includes the guiding portion and the second extending portion includes the guided portion, which simplifies the shapes of the drug solution container and the connector.

[0017] (5) In any one of the above items (2) to (4), it is preferable that the first extension portion or the second extension portion is formed in an annular shape.

[0018] Because the first extension portion or the second extension portion is annular, the first engagement portion included in the first extension portion or the second engagement portion included in the second extension portion is annularly provided. Therefore, the first engagement portion and the second engagement portion can be engaged over a wide range. As a result, the engagement between the first engagement portion and the second engagement portion is stable. This further improves the sealing ability of the closure body with respect to the drug solution discharge hole.

[0019] (6) In any one of the above items (3) to (5), it is preferable that the connecting needle pierces the sealing member while the guided portion is being guided by the guiding portion.

[0020] In this case, the connecting needle pierces the sealing member in a state in which misalignment of the connecting needle with respect to the sealing member is suppressed, thereby making it possible to suppress coring.

[0021] (7) In any one of the above items (1) to (6), the first engagement portion may be provided on the liquid medicine container.

[0022] According to this configuration, when the drug solution administration instrument does not include a housing that accommodates the drug solution container, it is possible to connect the connector to the drug solution container.

[0023] (8) In any one of the above items (1) to (6), when the medicinal solution administration instrument includes a housing that accommodates the medicinal solution container, the first engagement portion may be provided on the housing.

[0024] According to this configuration, in a drug solution administration device having a housing that accommodates a drug solution container, it is possible to connect the connector to the housing.

[0025] (9) In any one of the above items (1) to (8), the connector may have a protrusion that is larger in diameter than the connecting needle and that protrudes from the needle hub toward the sealing member when the connector is attached to the closure. In this case, when the connector is attached to the closure, the protrusion is inserted into the opening of the fixing member and presses the part of the sealing member toward the drug solution discharge portion.

[0026] In this configuration, the pressing portion presses the closure toward the chemical solution discharge portion, and the protruding portion presses the sealing member toward the chemical solution discharge portion, thereby achieving an even more liquid-tight seal between the chemical solution discharge portion and the sealing member. [Effects of the Invention]

[0027] In the present invention, when the connector is attached to the closure, the pressing portion of the connector presses the sealing member of the closure toward the liquid medicine discharge portion of the liquid medicine container. In this state, a first engagement portion provided on the outside of the liquid medicine discharge portion engages with a second engagement portion provided on the connector. Based on this engagement, the pressing portion maintains the state in which the sealing member is pressed toward the liquid medicine discharge portion. This improves the liquid-tightness between the liquid medicine discharge portion and the sealing member. This prevents the liquid medicine from leaking between the liquid medicine discharge portion and the sealing member.

[0028] Furthermore, even when pressure is applied to the medicinal liquid in the medicinal liquid container to administer it to a patient, the engagement is maintained, thereby maintaining a liquid-tight seal between the medicinal liquid discharge portion and the sealing member. That is, even in this case, leakage of the medicinal liquid from between the medicinal liquid discharge portion and the sealing member is prevented. [Brief explanation of the drawings]

[0029] [Figure 1] FIG. 1 is a schematic cross-sectional view of a main part of a drug solution administration device according to an embodiment of the present invention. [Figure 2] FIG. 2 is a schematic side view of a main part of a liquid medicine container constituting the liquid medicine administration device. [Figure 3]FIG. 3 is a schematic cross-sectional view of the essential parts of the drug solution administration device when attachment of the connector to the closure body begins. [Figure 4] FIG. 4 is a schematic cross-sectional view of the essential parts of the drug solution administration device when the attachment of the connector to the closure has been completed. [Figure 5] FIG. 5 is a schematic cross-sectional view of a main part of a medicinal solution administration apparatus according to a first modified example of the present invention. [Figure 6] FIG. 6 is a schematic cross-sectional view of the essential parts of a liquid medicine container and a closing body provided in a liquid medicine administration apparatus according to a second modified example of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0030] 1 is a schematic cross-sectional view of a main part of a drug solution dispensing device 10 according to this embodiment. The drug solution dispensing device 10 includes a drug solution container 100, a closure 200, and a connector 300.

[0031] The liquid medicine container 100 is, for example, a syringe. The base end of the liquid medicine container 100 is an open end, and a gasket is disposed inside the liquid medicine container 100 near the open end. The gasket is provided at the tip of a plunger. When the liquid medicine M is administered from the liquid medicine container 100 to a patient, the plunger moves toward the tip of the liquid medicine container 100 based on the operation of a user or an actuator. At this time, the gasket moves integrally with the plunger. Due to this movement, the liquid medicine M contained in the liquid medicine container 100 is pressed against the gasket and administered to the patient via the connecting needle 340. Since the above configuration is publicly known, illustrations of the gasket, plunger, actuator, etc. are omitted.

[0032] The liquid medicine container 100 has a liquid medicine storage portion 102 and a liquid medicine discharge portion 104. The liquid medicine storage portion 102 and the liquid medicine discharge portion 104 have a cylindrical shape, for example. When the liquid medicine storage portion 102 and the liquid medicine discharge portion 104 have a cylindrical shape, the inner and outer diameters of the liquid medicine discharge portion 104 are smaller than the inner and outer diameters of the liquid medicine storage portion 102. In addition, a tapered portion 106 is interposed between the liquid medicine storage portion 102 and the liquid medicine discharge portion 104. The diameter of the tapered portion 106 tapers from the liquid medicine storage portion 102 toward the liquid medicine discharge portion 104. The liquid medicine discharge portion 104 extends so as to protrude from the center of the tip of the tapered portion 106.

[0033] The hollow interior of the chemical solution accommodating portion 102 and the hollow interior of the tapered portion 106 form a chemical solution chamber 108. The hollow interior of the chemical solution discharge portion 104 forms a chemical solution discharge hole 112. The chemical solution discharge hole 112 communicates with the chemical solution chamber 108. The chemical solution discharge hole 112 and the chemical solution chamber 108 contain a chemical solution M.

[0034] At the tip of the drug solution discharge portion 104, the diameter gradually decreases as the distance from the drug solution storage portion 102 increases. This forms a diameter changing portion 110 at the tip of the drug solution discharge portion 104. An annular groove 114 is formed in a portion of the drug solution discharge portion 104 closer to the base end than the diameter changing portion 110. The annular groove 114 is recessed inward in the diameter direction of the drug solution discharge portion 104.

[0035] As shown in FIGS. 1 and 2 , the liquid medicine container 100 has a first extension portion 120. In this embodiment, the first extension portion 120 has an annular wall portion 121 protruding from the tip of the liquid medicine storage portion 102. The first extension portion 120 extends in a first direction from the base end of the liquid medicine container 100 toward the tip. The first extension portion 120 surrounds the liquid medicine discharge portion 104. The length from the base end to the tip of the annular wall portion 121 is greater than the length from the base end to the tip of the liquid medicine discharge portion 104. The outer diameter of the annular wall portion 121 is slightly smaller than the outer diameter of the liquid medicine storage portion 102.

[0036] The first extension portion 120 includes a guide portion 122. In this embodiment, the guide portion 122 includes a plurality of ribs 124 (see FIG. 2 ) and a first engagement portion 126. By configuring the first extension portion 120 to include such a guide portion 122, the shape of the drug solution container 100 can be simplified. The plurality of ribs 124 are provided at intervals in the circumferential direction of the annular wall portion 121. Each of the plurality of ribs 124 extends from the base end of the annular wall portion 121 along the first direction. The tip of the rib 124 is located at a predetermined position between the base end and the tip of the annular wall portion 121. In other words, the tip of the rib 124 does not reach the tip of the annular wall portion 121. The guide portion 122 may be located at a position separate from the first extension portion 120.

[0037] The first engagement portion 126 is provided at the tip of the annular wall portion 121. The first engagement portion 126 is a portion that bulges outward in the diameter direction of the annular wall portion 121 in a generally trapezoidal shape. Based on this bulge, the first engagement portion 126 has a shape like an annular claw that protrudes outward in the diameter direction of the annular wall portion 121 that constitutes the first extension portion 120. As described above, the first extension portion 120 includes the guide portion 122 and the first engagement portion 126. The side wall of the first engagement portion 126 has a first cam surface 128. The first cam surface 128 is an inclined surface that has a large diameter on the base end side and a small diameter on the tip end side.

[0038] As shown in FIG. 1 , the closure 200 includes a sealing member 210 and a fixing member 250. The sealing member 210 includes a cylindrical portion 212, a plug portion 214, and a convex portion 216. The plug portion 214 protrudes from a base end surface 218 of the cylindrical portion 212 in a spherical, conical, or cylindrical shape. The convex portion 216 protrudes from a distal end surface 220 of the cylindrical portion 212 in a spherical, conical, or cylindrical shape. When the sealing member 210 is viewed from the base end or the distal end, the centers of the plug portion 214, the cylindrical portion 212, and the convex portion 216 overlap each other. The maximum diameters of the plug portion 214 and the convex portion 216 are smaller than the diameters of the cylindrical portion 212.

[0039] Stopper portion 214 is inserted into chemical solution discharge hole 112. In this state, base end surface 218 of cylindrical portion 212 abuts against tip surface 130 of chemical solution discharge portion 104. Based on the above, outlet opening 132 of chemical solution discharge hole 112 is closed by stopper portion 214, and chemical solution discharge hole 112 is sealed by sealing member 210.

[0040] The sealing member 210 is made of a resilient material such as a medical rubber material (for example, butyl rubber, isoprene rubber, butadiene rubber, etc.) or various elastomer materials.

[0041] Fixing member 250 is a hollow body having an internal space. Fixing member 250 has a base portion 252 which is a base end portion, an annular portion 254, and a holding portion 256 which is a tip end portion. Annular portion 254 is a portion located between base portion 252 and holding portion 256. The outer diameter of annular portion 254 is smaller than the maximum outer diameter of base portion 252 and the maximum outer diameter of holding portion 256 (not shown).

[0042] The fixing member 250 is made of a synthetic resin material such as polyethylene, polypropylene, polycarbonate, polystyrene, acrylic, etc. Alternatively, the fixing member 250 is made of a metal material such as stainless steel, titanium alloy, aluminum alloy, etc.

[0043] Two engagement claws 260 are provided on the inner wall of the base portion 252. The two engagement claws 260 protrude inward in the diameter direction of the base portion 252 at positions spaced approximately 180° apart from each other. Two openings 262 are formed in the annular portion 254. The two openings 262 are spaced approximately 180° apart from each other.

[0044] The holding portion 256 holds the sealing member 210. The holding portion 256 is disposed inside the annular wall portion 121. The holding portion 256 is formed with an insertion recess 264 recessed from the base end toward the tip, and an opening 266. The internal spaces of the base portion 252 and the annular portion 254 communicate with the opening 266 via the insertion recess 264. The opening 266 is a circular opening. The diameter of the opening 266 is approximately equal to the inner diameter of the chemical solution discharge hole 112 (outlet opening 132). The insertion recess 264 accommodates the cylindrical portion 212 of the sealing member 210. The tip end surface 220 of the cylindrical portion 212 abuts against a ceiling surface 268 of the insertion recess 264. In this manner, the sealing member 210 is sandwiched between the chemical solution discharge portion 104 and the fixing member 250 in the axial direction of the chemical solution discharge portion 104.

[0045] The protrusion 216 of the sealing member 210 is inserted into the opening 266. In other words, the protrusion 216, which is a part of the sealing member 210, is exposed to the opening 266.

[0046] The chemical solution discharge portion 104 is inserted into the internal space of the base portion 252 and the annular portion 254. In other words, in the illustrated embodiment, the fixing member 250 is attached to the chemical solution discharge portion 104 so as to cover the chemical solution discharge portion 104 from the outside. At this time, two engaging claws 260 provided in the base portion 252 are inserted into the annular groove 114 of the chemical solution discharge portion 104. Furthermore, the diameter changing portion 110 of the chemical solution discharge portion 104 is inserted into the two openings 262 of the annular portion 254.

[0047] That is, the two engaging claws 260 engage with the annular groove 114, and the diameter changing portion 110 engages with the two openings 262. Furthermore, the inner wall of the base portion 252 comes into close contact with the outer peripheral wall of the chemical solution discharge portion 104. For the reasons described above, the fixing member 250 is held in the chemical solution discharge portion 104. By holding the fixing member 250 in the chemical solution discharge portion 104 in this manner, the sealing member 210 is positioned and fixed between the chemical solution discharge portion 104 and the fixing member 250.

[0048] Connector 300 has a cylindrical portion 302, a needle hub 304, and a pressing portion 306. A peripheral side wall 307 of cylindrical portion 302 constitutes a second extending portion 308. Second extending portion 308 extends in a second direction from the tip end of connector 300 toward the base end.

[0049] Two tongue portions 312 that are elastically deformable in the radial direction of the side peripheral wall 307 are provided on the side peripheral wall 307. The two tongue portions 312 are spaced apart from each other by approximately 180°. A U-shaped slit 310 is formed in the side peripheral wall 307 so as to surround the tongue portions 312. The tongue portions 312 extend in the second direction.

[0050] A claw-shaped second engagement portion 314 is provided on the inner surface of tongue portion 312 facing the hollow interior of tubular portion 302. A side wall of second engagement portion 314 has second cam surface 316. Second cam surface 316 is an inclined surface with a larger inner diameter on the base end side and a smaller inner diameter on the tip end side. When connector 300 is attached to closure 200, first engagement portion 126 and second engagement portion 314 engage with each other (see FIG. 4).

[0051] When the connector 300 is attached to the closure 200, the inner surface at the base end of the peripheral side wall 307 of the tubular portion 302 is guided while abutting against the first engaging portion 126 or the plurality of ribs 124 that constitute the guiding portion 122 (see FIGS. 3 and 4). In this way, the inner surface at the base end of the peripheral side wall 307 is a guided portion 320 that is guided by the guiding portion 122. Therefore, the second extending portion 308 includes the second engaging portion 314 and the guided portion 320. By configuring the second extending portion 308 to include the guided portion 320, the shape of the connector 300 can be simplified. Note that the guided portion 320 may be located at a location separate from the second extending portion 308.

[0052] The needle hub 304 and the pressing portion 306 are cylindrical portions extending in the second direction from the ceiling wall of the tubular portion 302. The needle hub 304 and the pressing portion 306 are positioned concentrically. The length of the needle hub 304 in the second direction is shorter than the length of the pressing portion 306 in the second direction. The length of the pressing portion 306 in the second direction is shorter than the length of the tubular portion 302 in the second direction.

[0053] When the connector 300 is attached to the closure 200, the pressing portion 306 presses the distal end surface 270 of the holding portion 256 of the fixing member 250. The pressing portion 306 is not limited to a cylindrical shape. For example, the pressing portion 306 may be configured to include a plurality of pressing pieces spaced apart in the circumferential direction so as to surround the connecting needle 340.

[0054] A retaining hole 330 extending in the second direction and a drug solution flow path 332 communicating with the retaining hole 330 are formed in the center of the needle hub 304. The tip of the connecting needle 340 is inserted into the retaining hole 330. This causes the connecting needle 340 to be held in the needle hub 304. The retaining hole 330 and the connecting needle 340 are located on the central axis C2 of the connector 300 or the tubular portion 302, as shown in FIG.

[0055] Connecting needle 340 has a lumen 342. Lumen 342 opens on the side of connecting needle 340 near the base end of connecting needle 340. This opening is a drug solution inlet 344. Lumen 342 opens at the tip of connecting needle 340. This opening is a drug solution outlet 346. Drug solution outlet 346 communicates with drug solution flow path 332.

[0056] When connector 300 is attached to closure 200, the base end of connecting needle 340 passes through opening 266 of fixing member 250, penetrates sealing member 210, and is inserted into medicinal solution discharge hole 112. As a result, medicinal solution inlet 344 is immersed in medicinal solution M inside medicinal solution discharge hole 112. In addition, medicinal solution discharge hole 112 and medicinal solution flow path 332 communicate with each other via lumen 342 of connecting needle 340.

[0057] The connecting needle 340 is made of a metal material such as stainless steel, copper alloy, titanium alloy, or aluminum alloy.

[0058] The connector 300 has a cylindrical connecting portion 350 extending in the first direction from the ceiling wall of the cylindrical portion 302. For example, an injection needle (not shown) is connected to the cylindrical connecting portion 350. Alternatively, a liquid supply tube (not shown) may be connected to the cylindrical connecting portion 350, and an injection needle may be attached to the tip of the liquid supply tube.

[0059] Next, preparations for administering the medicinal liquid M to a patient using the medicinal liquid administration device 10 will be described.

[0060] In the initial state before use, the medicinal solution administration device 10 has a closure 200 attached to the medicinal solution container 100 as shown in Fig. 1. Specifically, the closure 200 covers the medicinal solution discharge portion 104. In contrast, the connector 300 is not attached to the closure 200. The medicinal solution container 100 with the closure 200 attached and the connector 300 are separately sterilized.

[0061] When using the drug solution administration device 10, the user connects an injection needle, a liquid delivery tube, or the like to the cylindrical connecting portion 350 of the connector 300, and then attaches the connector 300 to the closure 200. Here, a typical example of the user is a patient, but the user is not limited to patients.

[0062] As shown in FIG. 1 , the user positions the connector 300 facing the distal end of the liquid medicine container 100. Next, as shown in FIG. 3 , the user moves the connector 300 toward the liquid medicine container 100. This movement causes the diametric end of the first engaging portion 126 to abut against the inner surface of the base end of the circumferential side wall 307 of the tubular portion 302. This abutment causes the central axis C2 of the tubular portion 302 and the central axis C1 of the liquid medicine discharge portion 104 to precisely align. In other words, so-called centering is achieved. This prevents the connecting needle 340 from becoming misaligned with the central axis C1 of the liquid medicine discharge portion 104. This also prevents the connecting needle 340 from tilting with respect to the central axis C1 of the liquid medicine discharge portion 104. At this point, the connecting needle 340 has not yet pierced the sealing member 210.

[0063] 3 , the user further moves connector 300 toward the base end of liquid medicine container 100. During this movement, the inner surface at the base end of side peripheral wall 307 remains in contact with first engagement portion 126. Therefore, as connector 300 moves toward the base end of liquid medicine container 100, tubular portion 302 is guided by first engagement portion 126.

[0064] As connector 300 moves further toward the base end of liquid medicine container 100, the inner surface of the base end of side peripheral wall 307 leaves first engagement portion 126 and comes into contact with multiple ribs 124. In this state, connector 300 moves toward the base end of liquid medicine container 100. Therefore, tubular portion 302 is guided by multiple ribs 124.

[0065] As described above, when the connector 300 moves toward the base end side of the drug solution container 100, the guided portion 320 provided on the connector 300 is guided by the guiding portion 122 provided outside the drug solution discharge portion 104 in the drug solution container 100.

[0066] As connector 300 moves toward the base end of drug solution container 100, the cutting edge of connecting needle 340 reaches opening 266 of fixing member 250. The cutting edge of connecting needle 340 passes through opening 266 and penetrates convex portion 216 inserted into opening 266 of sealing member 210. As described above, the cutting edge of connecting needle 340 penetrates convex portion 216 of sealing member 210 after the diametric end of first engaging portion 126 abuts against the inner surface of the base end of side peripheral wall 307 of tubular portion 302.

[0067] In other words, after the cylindrical portion 302 (or the connecting needle 340) and the medicinal solution discharge portion 104 (or the sealing member 210) are aligned and tilting of the connecting needle 340 is prevented, the cutting edge of the connecting needle 340 is inserted into the convex portion 216 of the sealing member 210. Therefore, the cutting edge of the connecting needle 340 is inserted into a predetermined position of the convex portion 216 from a direction approximately perpendicular to the diameter direction of the convex portion 216. This prevents coring from occurring due to the cutting edge of the connecting needle 340 being tilted with respect to the central axis C1 of the medicinal solution discharge portion 104.

[0068] Furthermore, as connector 300 moves toward the base end of drug solution container 100, second cam surface 316 of second engagement portion 314 slides against first cam surface 128 of first engagement portion 126. This causes second cam surface 316 to ride up on first cam surface 128. Accompanying this riding up, tongue portion 312 elastically deforms. Specifically, tongue portion 312 bends from the connection portion between tongue portion 312 and peripheral side wall 307 as a starting point, toward the outside in the diameter direction of tubular portion 302. Therefore, second engagement portion 314 easily passes through first engagement portion 126. As can be seen from the above, second engagement portion 314 protruding inward from tubular portion 302 does not interfere with attachment of connector 300 to closure 200.

[0069] Furthermore, the pressing portion 306 provided on the connector 300 comes into contact with the tip surface 270 of the holding portion 256 of the fixing member 250 .

[0070] When connector 300 moves further from the above state toward the base end of drug solution container 100, second engagement portion 314 passes first engagement portion 126, and then tongue portion 312 elastically returns inward in the diameter direction of tubular portion 302. As a result, first engagement portion 126 and second engagement portion 314 engage with each other, as shown in FIG.

[0071] The cutting edge of connecting needle 340 penetrates sealing member 210 and reaches inside medicinal solution discharge hole 112, as shown in Fig. 4. This allows medicinal solution discharge hole 112 and medicinal solution flow path 332 to communicate with each other via medicinal solution inlet 344, lumen 342, and medicinal solution outlet 346 of connecting needle 340. Furthermore, pressing portion 306 presses distal end surface 270 of holding portion 256 of fixing member 250 toward distal end surface 130 of medicinal solution discharge portion 104. In other words, pressing portion 306 applies a pressing force to fixing member 250 toward medicinal solution discharge portion 104.

[0072] This pressing force causes the fixing member 250 to move slightly along the chemical solution discharge portion 104 to a movement end position on the proximal side of the chemical solution discharge portion 104. During this movement, the engaging claw 260 provided on the fixing member 250 moves along the annular groove 114, and the diameter changing portion 110 of the chemical solution discharge portion 104 moves relatively along the opening 262 formed in the fixing member 250.

[0073] The sealing member 210 is sandwiched between the distal end surface 130 of the chemical solution discharge portion 104 and the ceiling surface 268 of the insertion recess 264 in the fixing member 250. Therefore, after the fixing member 250 has moved to the movement end position, a pressing force is applied from the pressing portion 306, causing the proximal end surface 218 of the cylindrical portion 212 of the sealing member 210 to come into close contact with the distal end surface 130 of the chemical solution discharge portion 104 with great pressure. Moreover, a stopper portion 214 is inserted into the outlet opening 132 of the chemical solution discharge portion 104. For the reasons described above, the outlet opening 132 of the chemical solution discharge hole 112 is liquid-tightly sealed by the sealing member 210. Therefore, leakage of the chemical solution M from between the outlet opening 132 and the sealing member 210 can be prevented.

[0074] After the connector 300 is attached to the closure 200 as described above, the injection needle is inserted into the patient. Next, the plunger is operated by the user or an actuator. The plunger and the gasket move together within the liquid medicine chamber 108 toward the tip of the liquid medicine container 100. This causes the liquid medicine M in the liquid medicine discharge hole 112 to move into the lumen 342 via the liquid medicine inlet 344 of the connecting needle 340. The liquid medicine M then travels through the lumen 342, the liquid medicine outlet 346, and the liquid medicine flow path 332 to be administered from the injection needle to the patient. The liquid medicine M in the liquid medicine chamber 108 is also pushed by the gasket, and the liquid medicine M is replenished into the liquid medicine discharge hole 112.

[0075] While the medicinal liquid M is being administered to the patient, the engagement between the first engagement portion 126 and the second engagement portion 314 is maintained. This maintains the state in which the sealing member 210 is pressed against the medicinal liquid discharge portion 104. Therefore, even while the medicinal liquid M in the medicinal liquid chamber 108 is pressed by the gasket, leakage of the medicinal liquid M from between the outlet opening 132 and the sealing member 210 is prevented.

[0076] Next, a medicinal solution dispensing apparatus 20 according to a first modified example will be described with reference to Fig. 5. Note that, with respect to the medicinal solution dispensing apparatus 20, the same components as those in the medicinal solution dispensing apparatus 10 are designated by the same reference numerals, and detailed description thereof will be omitted.

[0077] The drug solution administration device 20 includes a connector 360. The connector 360 has a protrusion 362 protruding from the needle hub 304. The retaining hole 330 extends from the needle hub 304 to the protrusion 362. The outer diameter of the protrusion 362 is smaller than the diameter of the opening 266. Therefore, the protrusion 362 can be inserted into the opening 266.

[0078] 5, when the connector 360 is attached to the closure 200, the protrusion 362 is inserted into the opening 266 and presses the convex portion 216. That is, in this case, the pressing portion 306 presses the fixing member 250 toward the medicinal solution discharge portion 104, and the protrusion 362 presses the sealing member 210 toward the medicinal solution discharge portion 104. This further improves the liquid-tightness between the distal end surface 130 of the medicinal solution discharge portion 104 and the proximal end surface 218 of the sealing member 210.

[0079] Next, a medicinal solution dispensing apparatus 30 according to a second modification will be described with reference to Fig. 6. Note that, with respect to the medicinal solution dispensing apparatus 30, components that are the same as those in the medicinal solution dispensing apparatuses 10 and 20 are given the same names, and detailed descriptions thereof may be omitted.

[0080] The medicinal solution dispensing instrument 30 constitutes, for example, a medicinal solution administration device. In this case, the medicinal solution dispensing instrument 30 includes a medicinal solution container 150 and a housing 158. The medicinal solution container 150 is accommodated inside the housing 158. In this configuration, the housing 158 is provided with an annular wall portion 161. The annular wall portion 161 constitutes a first extending portion 160. The annular wall portion 161 is provided with a plurality of ribs 164 and a first engaging portion 166. The first engaging portion 166 and the plurality of ribs 164 constitute a first guide portion 162. Therefore, the first extending portion 160 includes the first guide portion 162. The first engaging portion 166 has, for example, the same shape as the first engaging portion 126 and has a first cam surface 168. Each of the ribs 164 has, for example, the same shape as each of the ribs 124.

[0081] The medical solution administration apparatus 30 further includes, for example, a connector 300. The connector 300 may be replaced with a connector 360 shown in FIG.

[0082] In the medicinal solution dispensing apparatus 30, when the connector 300 is attached to the closure 200, the guided portion 320 of the connector 300 is guided by the first guiding portion 162 provided on the housing 158. Then, the second engaging portion 314 of the connector 300 engages with the first engaging portion 166 provided on the housing 158. This allows the medicinal solution dispensing apparatus 30 to achieve the same effects as the medicinal solution dispensing apparatus 10 or 20.

[0083] In the medical solution administration devices 10, 20, and 30, the annular wall portions 121 and 161 are covered with the connectors 300 and 360. That is, the connectors 300 and 360 are located outside the annular wall portions 121 and 161. Conversely, the annular wall portions 121 and 161 may cover the connectors 300 and 360. In this case, the connectors 300 and 360 are located inside the annular wall portions 121 and 161.

[0084] The present invention is not limited to the above disclosure, and various configurations can be adopted without departing from the gist of the present invention. [Explanation of symbols]

[0085] 10, 20, 30...Medicine administration device 100, 150...Medicine container 102: Liquid medicine storage section 104: Liquid medicine discharge section 108... Chemical solution chamber 110... Diameter change portion 112...chemical solution discharge hole 114...annular groove 120, 160...first extension part 121, 161...annular wall part 122, 162... Guide portion 124, 164... Rib 126, 166...First engaging part 200...Occluded body 210: Sealing member 250: Fixing member 256...holding portion 260...engaging claw 262...Opening 264...Insertion recess 266...Opening 300, 360...Connector 302...Cylindrical portion 304...Needle hub 306: Pressing portion 308: Second extending portion 310...Slit 312...Tongue portion 314...Second engaging part 320...Guided part 330...holding hole 340...connecting needle 342... Lumen 346... Drug solution outlet 350: Cylindrical connecting portion 362: Protrusion M: Chemical solution

Claims

1. A drug solution administration device comprising: a drug solution container; a closure body disposed at a tip of the drug solution container; and a connector attached to the closure body, the liquid medicine container includes a liquid medicine storage portion that stores the liquid medicine, a cylindrical liquid medicine discharge portion provided at a tip of the liquid medicine storage portion, and a liquid medicine discharge hole formed in the liquid medicine discharge portion that discharges the liquid medicine, the closing body has a sealing member made of an elastic body and liquid-tightly sealing the chemical solution discharge hole, a fixing member that positions and fixes the sealing member to the chemical solution container, and an opening formed in the fixing member through which a part of the sealing member is exposed, and the sealing member is sandwiched between the fixing member and the chemical solution discharge hole, the connector includes a connecting needle that passes through the opening of the fixing member and pierces the sealing member when the connector is attached to the closure, a needle hub that holds the connecting needle, and a pressing portion that presses the fixing member toward the drug solution discharge portion when the connector is attached to the closure, The drug solution administration device has a first engagement portion provided outside the drug solution discharge portion and a second engagement portion provided on the connector, and the first engagement portion and the second engagement portion engage with each other when the connector is attached to the closure.

2. 2. The drug solution administration device according to claim 1, comprising: a first extension portion extending in a first direction from the base end of the drug solution discharge portion toward the tip end and including the first engagement portion; and a second extension portion extending in a second direction from the tip end of the connector toward the base end and including the second engagement portion.

3. 2. The drug solution administration device according to claim 1, further comprising a guide portion and a guided portion, wherein the guide portion and the guided portion come into contact with each other while the connector is being attached to the closure, and the guided portion is guided by the guide portion.

4. 2. The drug solution administration device according to claim 1, further comprising: a first extending portion extending in a first direction from a base end toward a tip end of the drug solution discharge portion and including the first engaging portion; and a second extending portion extending in a second direction from the tip end toward the base end of the connector and including the second engaging portion, A drug solution administration device wherein the first extension portion includes a guiding portion and the second extension portion includes a guided portion, and when the connector is being attached to the closure, the guiding portion and the guided portion abut against each other, and the guided portion is guided by the guiding portion.

5. 5. The drug solution administration device according to claim 2, wherein the first extension portion or the second extension portion is formed in an annular shape.

6. 5. The drug solution administration device according to claim 3, wherein the connecting needle pierces the sealing member while the guided portion is being guided by the guiding portion.

7. The drug solution administration device according to claim 1 , wherein the first engagement portion is provided on the drug solution container.

8. The drug solution administration device according to claim 1 , further comprising a housing that accommodates the drug solution container, and the first engagement portion is provided on the housing.

9. 2. The drug solution administration device according to claim 1, wherein the connector has a diameter larger than that of the connecting needle and has a protrusion that protrudes from the needle hub toward the sealing member when the connector is attached to the obturator, When the connector is attached to the closure, the protrusion is inserted into the opening of the fixing member to press the part of the sealing member toward the drug solution discharge portion.

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