External composition for skin or hair care
Incorporating trimethoxybenzylidene pentanedione into skin and hair care compositions inhibits NADPH oxidase, effectively reducing ROS production and preventing photoaging.
Patent Information
- Application Number
- JP2024135142
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2024-07-26
- Publication Date
- 2026-02-05
AI Technical Summary
Existing topical skin and hair care compositions have not adequately suppressed UV-induced reactive oxygen species (ROS) production, leading to insufficient prevention of photoaging.
Incorporation of trimethoxybenzylidene pentanedione into skin and hair care compositions to inhibit NADPH oxidase activity, thereby reducing ROS production and preventing photoaging.
Trimethoxybenzylidene pentanedione effectively inhibits NADPH oxidase activation by UVA irradiation, suppressing ROS production and maintaining youthful skin.
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Figure 2026019947000001_ABST
Abstract
Description
[Technical Field]
[0001] The present invention relates to a topical skin or hair care composition containing trimethoxybenzylidene pentanedione. Here, the topical skin or hair care composition refers to skin care cosmetics such as face washes, lotions, creams, and packs; makeup cosmetics such as foundations, lipsticks, and mascaras; hair care cosmetics such as shampoos, conditioners, hair styling agents, hair growth agents, hair colorants, and permanent wave agents; body care cosmetics such as body soaps, slimming agents, UV protection agents, bath agents, and antiperspirants; and fragrance cosmetics such as perfumes and colognes, including legal cosmetics, quasi-drugs, and pharmaceuticals. [Background technology]
[0002] Skin aging occurs due to various factors other than aging, and in recent years, photoaging caused by ultraviolet rays has also become known.
[0003] Among ultraviolet rays, UVB causes inflammation of the epidermis, while UVA not only causes darkening but also penetrates the dermis and produces reactive oxygen species (ROS), which cause DNA damage and contribute to photoaging of the skin. UVA activates NADPH oxygenase in cells, promoting the production of ROS.
[0004] To prevent damage caused by UV rays, it is common to apply sunscreen preparations containing UV protection agents to the skin to block UV rays. It is also thought that ingredients with antioxidant activity can be effective against photoaging caused by UVA rays.
[0005] As a means of preventing the production of ROS that causes DNA damage, Patent Document 1 discloses the effect of a vegetable oil containing an α-linolenic acid derivative as an active ingredient in suppressing the increase in ROS caused by UV irradiation, while Patent Document 2 discloses the effect of a topical composition containing γ-oryzanol in suppressing ROS production caused by UVA. [Prior art documents] [Patent documents]
[0006] [Patent Document 1] Japanese Patent Application Publication No. 2019-202990 [Patent Document 2] Japanese Patent Application Publication No. 2020-180070 DISCLOSURE OF THE INVENTION [Problem to be solved by the invention]
[0007] Against this background, research has been conducted into ingredients that have the effect of suppressing UV-induced ROS production, and topical skin or hair care compositions have been developed, but the effects have not necessarily been satisfactory. [Means for solving the problem]
[0008] The present invention was made under the above circumstances, and provides a novel topical skin or hair care composition that suppresses ROS production by inhibiting NADPH oxidase activity and prevents photoaging by incorporating trimethoxybenzylidene pentanedione.
[0009] The present invention relates to a skin or hair care composition containing trimethoxybenzylidene pentanedione.
[0010] Claim 2 of the present invention is the external preparation composition for skin or hair according to claim 1, wherein the trimethoxybenzylidene pentanedione is contained in an amount of 0.01 to 5.0% by mass. [Effects of the Invention]
[0011] The trimethoxybenzylidene pentanedione of the present invention inhibits the activation of NADPH oxidase by UVA irradiation, thereby suppressing ROS production, thereby preventing photoaging caused by UV rays and maintaining youthful skin. [Brief explanation of the drawings]
[0012] [Figure 1] Figure 1 shows the inhibitory effect of the trimethoxybenzylidene pentanedione of the present invention on intracellular ROS production caused by UVA irradiation. It can be seen that when commercially available trimethoxybenzylidene pentanedione was added, the ROS level was lower than when it was not added. DETAILED DESCRIPTION OF THE INVENTION
[0013] The present invention will be described in detail below. The method for producing trimethoxybenzylidenepentanedione used in the present invention is not particularly limited, but a synthetic product is available as a commercial raw material "Synoxyl HSS" from Sytheon Ltd. in the United States.
[0014] The amount of trimethoxybenzylidene pentanedione of the present invention is 0.01 to 5.0% by mass, preferably 0.1 to 2.5% by mass, based on the total amount of the topical skin composition using the commercially available raw materials. When preparing a typical topical skin or hair care composition, if the amount is less than 0.01% by mass, the effect of suppressing ROS production and preventing photoaging is not achieved. Although it is possible to incorporate more than 2.5% by mass, up to 5.0% by mass, this is not preferred because the effect commensurate with the amount incorporated gradually saturates.
[0015] The effect of the topical skin or hair care composition of the present invention is to suppress UV-induced ROS production and prevent photoaging. Therefore, when the topical skin or hair care composition of the present invention is used in combination with an ingredient with antioxidant and UV protection effects, further photoaging protection effects can be expected. Examples of such ingredients include tocopherol, vitamin C and its derivatives, carotenoids, UV protection agents, and animal, plant, and mineral extracts.
[0016] In addition to the essential ingredients described above, the topical skin or hair care composition of the present invention may contain other ingredients that are typically used in topical skin or hair care compositions, such as cosmetics and pharmaceuticals. Examples of such other ingredients include the following. The topical skin or hair care composition of the present invention is produced by blending one or more of these ingredients with the essential ingredients described above in accordance with a conventional method.
[0017] The oily components include the following: Avocado oil, apricot kernel oil, olive oil, cocoa butter, beef tallow, sesame oil, wheat germ oil, camellia oil, safflower oil, hydrogenated moringa oil, soybean oil, tea seed oil, evening primrose oil, camellia oil, glycolipids, triglyceride (C10-18) glyceryl triphosphate, peppermint leaf oil, palm kernel oil, palm oil, castor oil, sunflower seed oil, boswellia serrata oil, macadamia seed oil, manuka oil, horse fat, melia azadirachta seed oil, cottonseed oil, Japan wax, (moringa oil / hydrogenated moringa oil) esters, coconut oil, lemon fruit oil, phospholipids, horseradish perilla seed oil, etc. Waxes such as carnauba wax, candelilla wax, rice bran wax, hydrogenated jojoba oil, sunflower seed wax, acacia dealbata flower wax, partially hydrogenated jojoba oil, jojoba ester, jojoba seed oil, beeswax, and lanolin. Hydrocarbons such as isoparaffin, hydrogenated polyisobutene, squalane, squalene, ceresin, paraffin, microcrystalline wax, liquid paraffin, and petrolatum. Higher fatty acids such as isostearic acid, oleic acid, stearic acid, palmitic acid, hydroxystearic acid, behenic acid, myristic acid, lauric acid, linoleic acid, and linolenic acid. Higher alcohols such as isostearyl alcohol, 2-octyldodecanol, oleyl alcohol, cholesterol, stearyl alcohol, cetyl alcohol, cetearyl alcohol, soybean sterol, phytosterols, behenyl alcohol, jojoba alcohol, myristyl alcohol, and lanolin alcohol. Alkyl glyceryl ethers such as chimyl alcohol and batyl alcohol. Isostearyl Isostearate, Phytostearyl Isostearate, Propylene Glycol Isostearate, Cetyl 2-Ethylhexanoate, Ethoxydiglycol Behenate, Ethoxydiglycol Oleate, Hydrolyzed Jojoba Esters, Triethyl Citrate, Diethylene Glycol Monoethyl Ether, Isosorbide Dicaprylate, Glycol Distearate, Propylene Glycol Dinonanoate, Cholesteryl Stearate, Stearyl Stearate, Caprylic / Capric Triglyceride, Triheptanoate Esters such as glyceryl tri-2-hexanoate, ethylhexyl palmitate, behenyl / oleic acid esters, pentaerythritol tetraester, isopropyl jojoba oil, jojoba oil / macadamia seed oil esters, ethyl macadamiate, phytosteryl macadamiate, isopropyl myristate, octyldodecyl myristate, butylene glycol coconut oil fatty acid, propylene glycol laurate, and diisostearyl malate. Silicones such as amino-modified silicone, alkyl-modified silicone, cyclic dimethyl silicone oil, silicone rubber, methylhydrogenpolysiloxane, methylphenylpolysiloxane, and methylpolysiloxane.
[0018] Examples of polyhydric alcohols include ethoxydiglycol, octanediol, polyglycerols such as glycerin, diethylene glycol and diglycerin, dipropylene glycol, 1,3-butylene glycol, propylene glycol, hexanediol, heptanediol, pentanediol, polyethylene glycol, and the like.
[0019] Examples of sugars include xylitol, sucrose, sorbitol, trehalose, lactose, fructose, maltitol, mannitol, and rhamnose.
[0020] Examples of the polymer compound include the following: Natural polymers such as Alcaligenes polysaccharides, alginic acid, casein, curdlan, carrageenan, agar, xanthan gum, chitosan, guar gum, quince seed, collagen, sclerotium gum, gelatin, dextrin, starch, hyaluronic acid, pullulan, pectin, and mannan. Natural polymer derivatives such as acetylated hyaluronic acid, ethyl cellulose, cationized guar gum, cationized cellulose, carboxymethyl cellulose, stearoxyhydroxypropyl methylcellulose, nitrocellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose, polyquaternium-10, polyquaternium-67, and methyl cellulose. Synthetic polymers such as POE-POP copolymer, alkyl acrylate copolymer, acrylic acid-acrylic acid amide-ethyl acrylate copolymer, acrylic resin alkanolamine, alkyl acrylate-vinyl acetate copolymer, acrylates copolymer Na, carboxyvinyl polymer, highly polymerized polyethylene glycol, polymeric silicone, silicone resin, (styrene / acrylates) copolymer, vinyl methyl ether-ethyl maleate copolymer, polyacrylic acid amide, polyacrylic acid sodium, polydimethylpiperidinium chloride, polyoxypropylene butyl ether, polyvinyl acetate, polyvinyl alcohol, and polyvinylpyrrolidone.
[0021] The surfactants include the following: Anionic surfactants such as acyl N-methyl taurine salts, POE alkyl ether carboxylates, POE alkyl ether sulfates, alkyl ether phosphate ester salts, alkylbenzenesulfonates, alkyl sulfate ester salts, N-acyl amino acid salts, α-olefin sulfonates, higher fatty acid soaps, sodium stearoyl glutamate, and sodium stearoyl lactylate. Cationic surfactants such as alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, and benzalkonium chloride. Amphoteric surfactants such as alkylamidopropyldimethylaminoacetic acid betaine, alkylamidobetaine, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, alkyldimethylaminoacetic acid betaine, hydrogenated lecithin, lysolecithin, and lecithin. POE Alkylamine / Fatty Acid Amide, POE Alkyl Ether, POE / POP Alkyl Ether Alkylamine Oxide, Alkyl Glucoside, PEG-6 Isostearate, Polyglyceryl-6 Isostearate, Ethoxydiglycol, PEG-8 Caprylic / Capric Glycerides, (Candelilla / Jojoba / Rice Bran) Polyglyceryl-3 Esters, Glycerin Fatty Acid Esters, POE Glycerin Fatty Acid Esters, Polyglyceryl-3 Diisostearate, Polyglyceryl-3 Dioleate, Polyglyceryl-6 Distearate, Fatty Acid Alkanolamides, PEG Fatty Acid Esters, PEG-40 Hydrogenated Castor Oil, Hydrogenated Sunflower Seed Oil Glyceryl Esters, Hydrogenated Sunflower Seed Oil Polyglyceryl-3 Esters, PEG-6 Stearate, PEG-32 Stearate, PEG Stearate Nonionic surfactants such as -75, glyceryl stearate, polyglyceryl-6 stearate, polyglyceryl-10 stearate, steareth-20, ceteth-20, sorbitan fatty acid esters, POE sorbitan fatty acid esters, POE sorbitan fatty acid esters, triisostearin PEG-6 esters, tribehenin PEG-20 esters, POE castor oil / hydrogenated castor oil, PEG-10 sunflower glycerides, glyceryl behenate, jojoba wax PEG-80 esters, jojoba wax PEG-120 esters, jojoba oil PEG-150 esters, polyoxyethylene beeswax, polyglyceryl-3 beeswax, polysorbate 80, polyglyceryl-6 polyhydroxystearate, polyglyceryl-6 polyricinoleate, PEG-16 macadamia glycerides, and PEG-8 beeswax.
[0022] Examples of coloring materials, powders, and particles include the following. Coloring materials such as inorganic pigments such as yellow iron oxide, carbon black, black iron oxide, red iron oxide, and ultramarine, pearl pigments, organic pigments, tar dyes, and natural dyes. Inorganic powders such as zinc oxide, alumina, (alumina / iron oxide / titanium oxide / mica) complex, (alumina / titanium oxide / sodium silicate / silica) complex, (alumina / titanium oxide / silica) complex, (alumina / titanium oxide / silica / dimethicone) complex, (alumina / silica) complex, (alumina / silica / talc) complex, mica, titanium mica, kaolin, magnesium aluminum silicate, titanium oxide, (titanium oxide / zirconium oxide / silica) complex, (titanium oxide / silica) complex, (titanium oxide / talc) complex, iron oxide, (iron oxide / titanium oxide / silica / mica) complex, (iron oxide / titanium oxide / mica) complex, (iron oxide / silica) complex, (iron oxide / silica / dimethicone) complex, silica, (silica / polyurethane-15 / mica) complex, (silica / mica) complex, zeolite, talc, hectorite, bentonite, mica, (mica / polyurethane-15) complex, and magnesium sodium silicate. Organic powders such as silk powder, cellulose powder, nylon powder, and polyethylene powder. Granules of fatty acid esters, cellulose, natural products, nylon, polyethylene, wax, etc.
[0023] Ingredients of natural origin include the following: Elastin, hydrolyzed casein, hydrolyzed keratin, hydrolyzed collagen, hydrolyzed silk, hydrolyzed soy protein, hydrolyzed pearl, chitin, chitosan, collagen, sodium chondroitin sulfate, water-soluble collagen, lactose, sodium hyaluronate, whey protein, peptides, and other substances of animal and microbial origin. Acacia Victoria Fruit Extract, Acacia Victoria Seed Extract, Actinidia Deliciosa Fruit Extract, Acronitia Acidula Fruit Extract, Asparagopsis Armata Extract, Acerola Fruit Extract, Anigozanthus Mangresi Flower Extract, Anigozanthus Flavidus Flower / Leaf Extract, Anetrea Anisata Leaf Extract, Alaria Esculenta Extract, Arctium Majus Root Extract, Arnica Montana Flower Extract, Aloe Ferox Leaf Extract, Aloe Vera Leaf Extract, Italian Cypress Leaf / Fruit / Stem Oil, Strawberry Fruit Extract, Ginkgo Biloba Leaf Extract, Iris Root Extract, Witha Nia somnifera root extract, Urtica dioica extract, Uva-ursi leaf extract, Ecklonia radiata extract, Rubus rubra fruit extract, Barley bark extract, Oriental thistle flower / leaf / stem extract, Barley seed extract, Panax ginseng root extract, Lamium extract, Amaranth flower extract, Orange fruit extract, Orange fruit water, Chamomile flower extract, Chamomilla recutita (matricaria) extract, Hydrolyzed wheat protein, Hydrolyzed soy protein, Oat kernel extract, Guarana seed extract, Carrot extract, Beta-carotene, Licorice root extract, Rubus idaeus extract, Rubus idaeus fruit Fruit extract, kiwi fruit extract, kiwi fruit water, Kigelia africana fruit extract, Yellow Amaranth extract, Caviar lime extract, Cucumber fruit extract, Leptospermum officinalis branch / leaf extract, Quillaja bark extract, Guava fruit extract, Wolfberry fruit extract, Sophora flavescens root extract, Cranberry fruit water, Grevillea speciosa flower extract, Grapefruit fruit water, Kunzea pomifera fruit extract, Caper fruit extract, Coconut water, Yeast extract, Rice bran water, Viola tricolor extract, Zanthoxylum piperitum seed extract, Santalum acuminatum fruit extract, Lithospermum root extract Ingredients: Syzygium reumanii fruit extract, Citrus glauca fruit extract, Ginger water, Birch extract, Horsetail extract, Japanese cedar bud extract, Black cherry fruit water, Spirulina platensis extract, Ivy leaf / stem extract, Horse chestnut seed extract, Ash bark extract, Sambucus nigra flower extract, Yarrow extract, Peppermint extract, Sage leaf extract, Mallow flower / leaf / stem extract, Rosa centifolia flower extract, Jasminum officinale flower / leaf extract, Tasmannia lanceolata fruit extract, Tasmannia lanceolata fruit / leaf extract,Davidsonia pruriens fruit extract, dulse extract, tea leaf extract, passionflower flower extract, centella asiatica extract, tea tree leaf extract, tea tree leaf oil, terminalia ferdinandiana fruit extract, angelica extract, calendula officinalis flower extract, carrot extract, tomato fruit / leaf / stem extract, kaede root extract, carrot root extract, garlic root extract, pineapple fruit extract, hibiscus flower extract, bakuchiol, bakuhousia anisa Leaf extract, Backhousia citriodora leaf extract, Lotus root water, Lotus flower extract, Papaya fruit extract, Hamamelis virginiana extract, Hamamelis virginiana bark / leaf / branch extract, Chayote fruit extract, Banksia serrata flower extract, Bambusa arundinacea stem, Daisy flower extract, Hinokitiol, Fucus extract, Hippophae rhamnoides extract, Himantaria elongata extract, Loquat leaf extract, Grape fruit water, Grape leaf extract, Beech tree seedling extract, Plumeria flower extract , Pleioginium timolense fruit extract, Luffa extract, Safflower extract, Cucurbita pepo fruit extract, Persian Walnut seed extract, Henna flower / fruit / leaf extract, Podocarpus elatus fruit extract, Madake extract, Mangifera indica fruit extract, Microcitrus australasica fruit extract, Microcitrus austris fruit extract, Mimosa tenuiflora bark extract, Pufferfish bamboo shoot water, Peach leaf extract, Cornflower flower extract, Vegetable oil, Willow herb flower Plant-based ingredients such as: / leaf / stem extract, eucalyptus extract, European birch bark extract, European beech bud extract, Ranunculus ficaria extract, Laventula hybrida oil, Labdanum oil, lavender flower / leaf / stem extract, apple fruit extract, apple fruit water, Rumex occidentalis extract, lemon fruit extract, lemon fruit water, lemon myrtle leaf, rose water, rosemary leaf extract, lowbush blueberry fruit extract, wine extract, etc. Mineral origins such as extracts of olivine, malachite, hematite, smithsonite, rhodochrosite, etc.
[0024] Examples of disinfectants and preservatives include: Benzoic acid and its salts, benzalkonium chloride, isopropylmethylphenol, chlorhexidine, salicylic acid and its salts, zinc pyrithione, sorbic acid and its salts, dehydroacetic acid and its salts, triclosan, 4-terpineol, trichlorocarbanilide, parahydroxybenzoic acid esters (methylparaben, ethylparaben, butylparaben, etc.), piroctone olamine, phenoxyethanol, hexachlorophene, hexylresorcinol, methylisothiazolinone, methylchloroisothiazolinone, etc.
[0025] Antioxidants include the following: Sodium bisulfite, vitamin C and its derivatives, vitamin E (tocopherols), butylhydroxyanisole, butylhydroxytoluene, gallic acid esters, etc. Antioxidant aids such as ascorbic acid, citric acid, cephalin, succinic acid, phytic acid, malonic acid, maleic acid, phosphoric acid, etc.
[0026] Examples of sequestering agents include: edetate, citrate, hydroxyethanediphosphonate, phytic acid, malate, etc.
[0027] Examples of UV protection agents include the following: Examples of suitable antiperspirants include urocanic acid, ethylhexyl triazone, octocrylene, ethylhexyl salicylate, diethylaminohydroxybenzoylhexyl benzoate, para-aminobenzoic acid, octyl paradimethylaminobenzoate, bisethylhexyloxyphenol methoxyphenyl triazine, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, phenylbenzimidazole sulfonic acid, t-butyl methoxydibenzoylmethane, homosalate, polysilicone-15, methylenebisbenzotriazolyltetramethylbutylphenol, ethylhexyl methoxycinnamate, and 2-methylphenyl 4-methoxycinnamate.
[0028] Examples of pH adjusters include the following: Organic and inorganic alkaline agents such as aminomethylpropanol, aminomethylpropanediol, ammonia water, potassium hydroxide, sodium hydroxide, sodium carbonate, triethanolamine, tromethamine, monoethanolamine, and arginine. Organic and inorganic acids such as citric acid, lactic acid, phosphoric acid, malic acid, and HCl.
[0029] The various physiologically active ingredients include the following: To prevent rough skin, it contains polyhydric alcohols such as glycerin and POE methyl glucoside, and sugars such as trehalose and pullulan. Biopolymers such as elastin, chitin / chitosan, sodium chondroitin sulfate, and sodium hyaluronate. Moisturizers such as amino acids, sodium lactate, urea, betaine, and PCA-Na. Lipid components such as cholesterol, sphingolipids, ceramides, and phospholipids. Anti-inflammatory agents such as ε-aminocaproic acid, allantoin, lysozyme chloride, guaiazulene, glycyrrhizinic acid derivatives, β-glycyrrhetinic acid, and hydrocortisone. Other ingredients include allantoin and antihistamines. Various UV protection agents for anti-aging purposes. Antioxidants such as acetylcysteine, acetylzingerone, oxothiazolidine, ethylbisiminomethylguaiacol manganese chloride, caffeic acid derivatives, carotenoids, glutathione, tannins, vitamins (B2, C, E), hydroxyethylmethylthiopropenamide, flavonoids, ubiquinone, lignans, and lycopene. Cell activators such as alpha-hydroxy acids. Blood flow promoters such as gamma-oryzanol and vitamin E and its derivatives. For the purpose of whitening, derivatives of vitamin C, sodium ascorbate, magnesium ascorbyl phosphate, ascorbic acid glucoside, etc. Melanin inhibitors such as arbutin, ellagic acid, kojic acid, linoleic acid, linolenic acid, lactic acid, tranexamic acid, etc. Other ingredients include aminoethylphosphinic acids, sulfur, glutathione, placenta extract, etc. Alpha-hydroxy acids such as citric acid, glycolic acid, tartaric acid, lactic acid, and malic acid, and retinoids (vitamin A derivatives) for the purpose of preventing wrinkles. For hair growth, vasodilators such as capronium chloride and nicotinic acid benzyl ester, local stimulants such as capsicum tincture and ginger tincture, female hormones such as estradiol and ethinylestradiol, and sebum secretion inhibitors such as pyridoxine hydrochloride. Climbazole, zinc pyrithione, piroctone olamine, etc. are used to prevent dandruff and itching. For the purpose of preventing acne, keratolytic and exfoliating agents such as sulfur, salicylic acid, and resorcinol, and disinfectants such as benzalkonium chloride and halocarban. Antiperspirants such as aluminum chloride, aluminum chlorohydrate, and zinc oxide are used to prevent underarm odor. For the purpose of various other physiological activities, vitamins such as pantothenic acid, pantethine, vitamin A and its derivatives, nicotinamide, vitamin B2 and its derivatives, vitamin B6 hydrochloride, vitamin B6 dioctanoate, vitamin B6 tripalmitate, vitamin B12, vitamin B15 and its derivatives, vitamin C such as ascorbic acid, ascorbic acid dipalmitate, ascorbic acid phosphate ester (salt), vitamin D, vitamin E such as α-tocopherol, β-tocopherol, γ-tocopherol, vitamin E acetate, vitamin E nicotinate, and vitamin H are also included. Amino acids and their derivatives, such as asparagine, aspartic acid, acetylcitrullamidoarginine, alanine, arginine, carboxyethylaminobutyric acid, glycine, glutamylamidoethylimidazole, glutamylamidoethylindole, glutamine, serine, taurine, tyrosine, decarboxycarnosine HCl, threonine, valine, histidine, hydroxyproline, pyroglutamylamidoethylindole, phenylalanine, prolinamidoethylindole, methylpropylamidoacetylmethionine, and leucine. Protein-related substances, such as acetyl tetrapeptide-2, acetyl hexapeptide-1, trifluoroacetyl tripeptide-2, tripeptide-1, nanopeptide-1, and palmitoylpeptide-1. Silanol derivatives such as ascorbyl methylsilanol pectin, aspartic acid methylsilanol hydroxyproline, alginic acid siloxanetriol, glutamic acid silanediol, salicylic acid silanediol, dioleyl tocopheryl methylsilanol, dimethyl oxobenzodioxasilane, silanetriol, silanetriol alginate, silanetriol trehalose ether, hyaluronic acid dimethylsilanol, polysilicone-3, methylsilanol acetyl tyrosine, methylsilanol sodium lactate, mannuronate acefylline methylsilanol, mannuronate methylsilanol, lysine silanetriol, PCA copper methylsilanol, and slimming-related ingredients such as caffeine and dulse extract.
[0030] The formulation of the topical skin or hair care composition of the present invention may be in the form typically used for topical skin or hair care compositions, such as a liquid, emulsion, cream, gel, mist, aerosol foam, solid, or powder dispersion. [Example]
[0031] The present invention will now be described in more detail with reference to examples. However, the present invention is not limited to these examples. The blending amounts are expressed in mass % unless otherwise specified.
[0032] Example 1 Table 1 shows an example of a sun care mist formulation. [Table 1]
[0033] Example 2 Table 2 shows an example of a skin care cream (W / O) formulation. [Table 2]
[0034] Example 3 Table 3 shows an example of the formulation of an oil beauty serum. [Table 3]
[0035] Example 4 Table 4 shows an example of a skin care cream (O / W) formulation. [Table 4]
[0036] Example 5 Table 5 illustrates a skin care gel formulation. [Table 5]
[0037] Example 6 Table 6 shows an example of a hair cream formulation. [Table 6] [Industrial Applicability]
[0038] The present invention can be widely used in the industries of producing and selling external preparation compositions such as cosmetics, quasi-drugs, and pharmaceuticals.
Claims
1. A skin or hair care composition for external use, characterized by containing trimethoxybenzylidene pentanedione.
2. 2. The external skin or hair care composition according to claim 1, wherein the trimethoxybenzylidene pentanedione is present in an amount of 0.01 to 5.0% by mass.
Citation Information
Patent Citations
Skin photoaging preventive agent and functional cosmetic containing the same
JP2019202990A
Anti-skin aging composition for external use
JP2020180070A