Scented microneedle sheet and method for manufacturing the same

Abstract

We provide scented microneedle sheets that can continuously release fragrance. [Solution] The scented microneedle sheet (1) comprises an adhesive sheet (2) including a base layer (20) and an adhesive layer (21), and a needle sheet (3) including fine protrusions (30) containing effective skin-beautifying ingredients. The adhesive sheet (2) includes a fragrance region (A1) to which fragrance components are attached and a functional region (A2) to which the needle sheet is attached.

Description

Technical Field

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[0001] The present invention relates to a micro-needle sheet having an aroma and a method for producing the same.

Background Art

[0002] JP-A-2022-74152 (Patent Document 1) discloses a water-soluble cosmetic sheet to which a fragrance can be added as a raw material.

Prior Art Documents

Patent Documents

[0003]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0004] However, even when a fragrance is added to a raw material of a cosmetic such as a micro-needle sheet, it may volatilize during the manufacturing process, making it difficult to impart a scent.

[0005] The present invention has been made to solve the above problems, and an object thereof is to provide a scented micro-needle sheet that can continuously emit an aroma.

Means for Solving the Problems

[0006] The scented micro-needle sheet according to one aspect of the present invention includes an adhesive sheet including a base material layer and an adhesive layer, and a needle sheet including fine protrusions containing an effective skin-beautifying component. The adhesive sheet includes an aromatic region to which a scent component is attached and a functional region to which the needle sheet is attached.

[0007] Preferably, the adhesive sheet and the needle sheet do not contain a fragrance.

[0008] Preferably, the fragrance components include one or more fragrance components selected from the group consisting of linalool, α-pinene, limonene, terpinen-4-ol, α-santalol, geraniol, furanodesma 1,3-diene, linalyl acetate, isobutyl angelicate, patchouli alcohol, benzyl acetate, carotol, α-himacalene, estragol (methyl chavicol), sabinene, and β-phenethyl alcohol.

[0009] Preferably, the needle sheet is further provided with a protective plate that protects the fine protrusions at a position opposite to one side of the needle sheet.

[0010] A method for manufacturing a scented microneedle sheet according to one aspect of the present invention comprises the steps of: preparing a mold having fine recesses; filling the mold with raw materials for the needle sheet; drying the mold filled with raw materials; processing the dried needle sheet into a desired shape; attaching an adhesive sheet to the needle sheet after the processing step; processing the adhesive sheet into a desired shape to obtain an untreated microneedle sheet; and attaching fragrance components of a fragrance to at least the adhesive sheet of the untreated microneedle sheet.

[0011] Another aspect of the present invention relates to a method for manufacturing a scented microneedle sheet, comprising the steps of: preparing an adhesive sheet; attaching fragrance components of a fragrance to the adhesive sheet; preparing a mold having fine recesses; filling the mold with raw materials for the needle sheet; drying the mold filled with raw materials; processing the dried needle sheet into a desired shape; attaching an adhesive sheet with fragrance components attached to the processed needle sheet; and processing the adhesive sheet into a desired shape.

[0012] Preferably, the step of attaching the fragrance components of the fragrance is to hold the fragrance components in a housing filled with the fragrance components for a certain period of time, thereby attaching the fragrance components to at least the adhesive sheet.

[0013] Preferably, the fragrance contains fragrance components that adhere to the adhesive sheet.

[0014] Preferably, the fragrance includes at least one fragrance selected from the group consisting of lavender, geranium, rosemary, sweet orange, sweet marjoram, grapefruit, sandalwood, bergamot, lemon, frankincense, ylang-ylang, Roman chamomile, clary sage, juniper berry, neroli, rose, carrot seed, cypress, cedarwood, jasmine, basil, patchouli, palmarosa, petitgrain, myrrh, and rosewood. [Effects of the Invention]

[0015] The scented microneedle sheet of the present invention can continuously emit fragrance. [Brief explanation of the drawing]

[0016] [Figure 1] This figure shows a scented microneedle sheet according to one embodiment of the present invention, where (a) is a plan view and (b) is an explanatory diagram showing a cross-section. [Figure 2] This is a flowchart illustrating a method for manufacturing a scented microneedle sheet according to one embodiment of the present invention. [Figure 3] This is a flowchart illustrating a method for manufacturing a scented microneedle sheet according to a modified version of one embodiment of the present invention. [Figure 4] This graph evaluates the psychological state before and after using the microneedle sheet; (a) shows a comparative example, and (b) shows Example 1. [Figure 5] The graphs show the evaluation results of the persistence of fragrance components in scented microneedle sheets, with (a) showing Example 2 and (b) showing Example 3. [Modes for carrying out the invention]

[0017] Embodiments of the present invention will be described in detail with reference to the drawings. In the drawings, the same or corresponding parts are denoted by the same reference numerals, and their descriptions will not be repeated.

[0018] <Regarding the structure> Referring to FIG. 1, a scented micro needle sheet (also referred to as "micro needle sheet" in the following description) 1 according to the present embodiment will be described. The scented micro needle sheet 1 includes an adhesive sheet 2 and a needle sheet 3 including fine convex portions 30 containing an effective skin care ingredient. The adhesive sheet 2 includes an aromatic region A1 to which a scent component adheres and a functional region A2 to which the needle sheet 3 is attached.

[0019] The micro needle sheet 1 is a skin care item that can penetrate into the skin by solidifying an effective skin care ingredient such as hyaluronic acid into a substantially needle shape and adhering it to the skin. The micro needle sheet 1 is used by being attached to the skin for several hours, for example, overnight (about 5 to 8 hours). The micro needle sheet 1 can exhibit various effects according to the contained effective skin care ingredient, and can have effects such as a moisturizing effect, a blood circulation promoting effect, an effect of improving dark circles and dullness, an effect of improving wrinkles and sagging, a toning effect, a whitening effect, etc.

[0020] The adhesive sheet 2 includes a base material layer 20 and an adhesive layer 21. The shape of the adhesive sheet 2 can be appropriately designed according to a desired shape, and for example, a shape along the eye bag (tear trough), a shape covering a stain, a shape along the mouth, a shape along the nasolabial fold, a shape covering the glabella, etc., a shape corresponding to a concerned part may be adopted, or a geometric shape such as a circular shape or a polygonal shape may be adopted. Thereby, an effective skin care ingredient can be locally applied to a part where the user desires skin improvement.

[0021] The base material layer 20 is a film-like base material for facilitating handling of the adhesive layer 2 by the user. The material of the base material layer 20 is preferably, for example, a film, a non-woven fabric, a woven fabric, etc., and the material of the base material layer 20 is appropriately selected from resins or fibers such as urethane, olefin, vinyl chloride, cotton, rayon, cellulose, etc. Thereby, it can easily follow the movement of the skin and the shape of the part.

[0022] The adhesive layer 21 maintains the needle sheet 3 in close contact with the skin for several hours. The material of the adhesive layer 21 is typically an acrylic adhesive, but can be selected from, for example, acrylic adhesives, urethane adhesives, silicone adhesives, or rubber adhesives. This makes it less likely to cause skin irritation even when applied to the skin for several hours.

[0023] The thickness of the adhesive layer 21 is, for example, 10 to 1000 μm, preferably 15 to 100 μm. By making the thickness 15 μm or more, a sufficient amount of fragrance components can be attached to the adhesive layer 21.

[0024] The needle sheet 3 includes one surface 31 on which the fine protrusions 30 are arranged, and the other surface 32 which is attached to the adhesive layer 21. The size of the needle sheet 3 in this embodiment is slightly smaller than the outer dimensions of the adhesive sheet 2, and it is positioned so as to be bordered by the adhesive sheet 2 in a plan view.

[0025] The fine protrusions 30 are arranged in large numbers on one surface 31 of the needle sheet and contain a water-soluble polymer, which is the main component, and an effective skin-beautifying ingredient. The effective skin-beautifying ingredient is at least one component selected from the group consisting of, for example, hyaluronic acid, niacinamide, retinol, retinal, tranexamic acid, bakuchiol, glycyrrhizic acid, glutathione, collagen, centella asiatica extract, placenta extract, ceramide, retinoic acid tocopheryl, tocopherol, stem cell culture fluid, vitamin C derivatives, and plant and animal extracts. The plant and animal extracts referred to here are not particularly limited as long as they are commonly used in pharmaceuticals, cosmetics, etc. Vitamin C derivatives include, for example, sodium ascorbate and magnesium ascorbyl phosphate.

[0026] The shape of the micro-protrusions 30 can be approximately needle-shaped, and can take shapes such as cone, frustocone, pyramidal, frustocone, conical (volcanic), or cylindrical. Here, "approximately needle-shaped" is preferably a shape that tapers towards the tip. This makes it easier for the protrusions to penetrate the stratum corneum. In this embodiment, the micro-protrusions 30 are arranged as a single component on one surface of the needle sheet 3, but they may be arranged as separate components.

[0027] The height of the micro-protrusions 30 is, for example, 20 μm to 1000 μm, preferably 50 μm to 200 μm. This allows the micro-protrusions 30 to penetrate between the stratum corneum of the skin, enabling effective skin-beautifying ingredients to penetrate into the epidermis.

[0028] In this embodiment, the needle sheet 3 has been described as a single sheet including the micro-protrusions 30, but it may also be composed of only multiple micro-protrusions 30. In this case, the other side 32 of the micro-protrusions 30 is attached to the adhesive layer 21.

[0029] Furthermore, the microneedle sheet 1 of this embodiment further includes a protective plate 4 that protects the fine protrusions 30 at a position facing one surface 31 of the needle sheet 3. The protective plate 4 of this embodiment has substantially the same shape as the adhesive sheet 2, and the surface facing one surface 31 of the needle sheet 3 is provided with a recess that can receive the fine protrusions 30 of the needle sheet 3. In other words, the protective plate 4 can protect the fine protrusions 30 while keeping the adhesive sheet 2 hygienic. Note that the protective plate 4 does not have to be substantially the same shape. For example, the protective plate 4 may be slightly larger than the adhesive sheet 2, or multiple adhesive sheets 2 may be arranged on a single protective plate.

[0030] The thickness of the protective plate 4 is preferably 500 μm to 1500 μm, from the viewpoint of facilitating the peeling of the adhesive sheet 2. If the thickness of the protective plate 4 is less than 500 μm, the adhesive sheet 2 may be difficult to peel off and may be difficult to handle.

[0031] The protective plate 4 is typically made of resin, but it is sufficient if it can suitably peel off the adhesive sheet 2 and the needle sheet 3. The material of the protective plate 4 can be selected from a variety of materials, such as acrylic resin, polyethylene resin, polypropylene resin, vinyl chloride resin, ABS resin, and silicone resin. The protective plate 4 may also be composed of multiple materials, such as a paper or cloth plate with resin coated on one side.

[0032] <About fragrance components> The adhesive sheet 2 of the scented microneedle sheet 1 according to this embodiment includes a fragrance region A1 to which fragrance components are attached and a functional region A2 to which the needle sheet 3 is attached.

[0033] Fragrance components are volatile and gaseous components found in fragrances such as aroma oils, essential oils, and perfumes. While fragrance components can include a variety of components, it is preferable to select them appropriately according to the desired effect, such as relaxation or ease of falling asleep. Fragrance components can include one or more components selected from the group consisting of, for example, linalool, α-pinene, limonene, terpinen-4-ol, α-santalol, geraniol, furanoidesum 1,3-diene, linalyl acetate, isobutyl angelicate, patchouli alcohol, benzyl acetate, carotol, α-himacalene, estragol (methyl chavicol), sabinene, and β-phenethyl alcohol. These fragrance components are known to be components found in natural fragrances that can be extracted from plants.

[0034] Fragrance region A1 is the area of ​​the adhesive layer 21 that surrounds the needle sheet 3 in a plan view. In other words, fragrance region A1 is the area on the surface of the adhesive layer 21 to which fragrance components are attached. Functional region A2 is the area of ​​the adhesive layer 21 to which the needle sheet 3 is attached. Functional region A2 can perform various functions depending on the effective skin-beautifying ingredients contained in the needle sheet 3, such as moisturizing function, whitening function, and dullness improvement function.

[0035] It should be noted that, due to the characteristics of the fragrance components, fragrance components may adhere to areas other than the fragrance area A1 (so-called "fragrance transfer"). If fragrance transfer occurs, priority will be given to designating the functional area A2, and the other areas will be designated as the fragrance area A1. In other words, the microneedle sheet 1 of this embodiment may have fragrance adhering to other components such as the needle sheet 3 and the protective plate 4. The microneedle sheet 1 of this embodiment should have the strongest degree of fragrance component adhesion in the fragrance area A1.

[0036] Here, the adhesive layer 21 has two characteristics for adhering to the object to be adhered to. One is that the surface of the adhesive layer 21 has numerous irregularities, and the other is that it generates intermolecular forces between the adhesive layer 21 and the object to be adhered to. Due to these characteristics, the adhesive sheet 2 is difficult to peel off from the skin. As a result of diligent research, the inventors of this application have discovered a scented microneedle sheet 1 to which fragrance components adhere, by utilizing the above two characteristics of the adhesive layer 21. That is, the fragrance components penetrate between the irregularities of the adhesive layer 21, and intermolecular forces act between the fragrance components and the adhesive layer 21, making it possible to provide a scented microneedle sheet 1 that provides a long-lasting fragrance.

[0037] Conventional microneedle sheets include a drying process in their manufacturing process, making it difficult to obtain microneedle sheets with a long-lasting fragrance because the fragrance contained in the raw materials evaporates. Furthermore, even if fragrance is included in the raw materials, there is a risk of skin irritation if the fragrance is in contact with the skin for a long time. In contrast, the microneedle sheet 1 of this embodiment does not contain fragrance. The microneedle sheet 1 can release a long-lasting fragrance while preventing skin irritation caused by fragrance.

[0038] <Regarding the manufacturing method> Next, with further reference to Figure 2, a method for manufacturing the scented microneedle sheet 1 according to this embodiment will be described.

[0039] First, a mold having micro-recesses is prepared (preparation step S1). The shape of the micro-recesses corresponds to the micro-protrusions 30. The mold can be created by various methods, such as injection molding, press molding, laser irradiation, or 3D printing.

[0040] Next, the prepared mold is filled with the raw materials for the needle sheet 3 (filling step S2). The raw materials for the needle sheet 3 in this embodiment include, for example, sodium hyaluronate, glycerin, water, and sodium dilauroyl glutamate lysine. In addition to the effective skin-beautifying ingredients, the raw materials may contain various components such as moisturizers, antibacterial agents, thickeners, emulsifiers, pH adjusters, antioxidants, and solvents, but they do not contain fragrances. This prevents skin irritation caused by fragrances.

[0041] Next, the mold filled with the raw material is dried (drying step S3). Drying step S3 only requires drying the raw material, and various drying methods can be used, such as room temperature drying, forced air drying, or heated drying. In the case of heated drying, care should be taken to prevent the raw material containing effective skin-beautifying ingredients from denature. This solidifies the raw material filled in the mold, and the needle sheet before processing is formed. After drying step S3, the dried needle sheet is processed into the desired shape (processing step S4). Processing step S4 may include, for example, die-cutting to cut the needle sheet into the desired shape, or needle molding to extract only the needle portion from the needle sheet formed in the mold.

[0042] Next, an adhesive sheet is attached to the other side 32 of the needle sheet 3 (attachment step S5). In this embodiment, the adhesive sheet is attached to the mold so as to cover the other side 32 of the needle sheet 3. The adhesive sheet and / or mold in this state are then die-cut into the desired shape to obtain an untreated microneedle sheet (second processing step S6). If the mold is also die-cut at the same time, the mold functions as a "protective plate 4" that protects the fine protrusions 30 of the microneedle sheet. In other words, since the fine protrusions 30 of the microneedle sheet in this embodiment are manufactured without ever being peeled off the mold, the surface that is attached to the skin can be kept hygienic.

[0043] Next, the untreated microneedle sheet is held for a certain period of time inside a housing filled with fragrance components of the fragrance. This causes at least the fragrance components to adhere to the adhesive sheet 2, completing the scented microneedle sheet 1 (fragrance component attachment step S7). The fragrance is a liquid component such as essential oil, aroma oil, perfume, etc., and includes fragrance components, which are volatile gaseous components that adhere to the adhesive sheet 2. In other words, the fragrance components are what remains after the volatile components of the fragrance have evaporated. Thus, according to the manufacturing method of this embodiment, the fragrance (fragrance components) does not undergo a drying process, so it is possible to prevent the disappearance or deterioration of the fragrance components.

[0044] The fragrance contains one or more fragrance components, and various types can be used depending on the user's needs. The fragrance of this embodiment contains at least one fragrance selected from the group consisting of lavender, geranium, rosemary, sweet orange, sweet marjoram, grapefruit, sandalwood, bergamot, lemon, frankincense, ylang-ylang, Roman chamomile, clary sage, juniper berry, neroli, rose, carrot seed, cypress, cedarwood, jasmine, basil, patchouli, palmarosa, petitgrain, myrrh, and rosewood. Table 1 is a table showing the main fragrances and the main fragrance components they contain.

[0045] [Table 1]

[0046] According to the manufacturing method of the microneedle sheet 1 of this embodiment, fragrance components are attached even though no fragrance is present. This prevents skin irritation caused by fragrance, allowing even users with sensitive skin to use the scented microneedle sheet. Furthermore, in the microneedle sheet market, where the inclusion of fragrance has traditionally been avoided, this invention provides a microneedle sheet with new added value. In other words, the microneedle sheet not only provides the skin-beautifying effect of the needle sheet, but also adds effects derived from fragrance components, such as relaxation and refreshment, which were difficult to impart with conventional microneedle sheets.

[0047] (modified version) Next, with reference to Figures 1 and 3, a modified version of the method for manufacturing the scented microneedle sheet 1 of the above embodiment will be described. The modified version of the method for manufacturing the microneedle sheet 1 is basically the same as the method for manufacturing the above embodiment, but differs in that an adhesive sheet with the scent attached is prepared in advance.

[0048] First, an adhesive sheet is prepared (adhesive sheet preparation step S10). The prepared adhesive sheet is then held inside a casing filled with fragrance components for a certain period of time to allow the fragrance components to adhere (fragrance component adhesion step S11).

[0049] Steps S11 onward are substantially the same as the manufacturing method according to the above embodiment. Specifically, a mold having fine recesses is prepared (preparation step S12). The raw material for the needle sheet 3 is filled into the prepared mold (filling step S13). The mold filled with the raw material is dried (drying step S14). After the drying step S14, the dried needle sheet is processed into a desired shape (processing step S15). An adhesive sheet with fragrance components attached is attached to the needle sheet 3 after the processing step S15 (attachment step S16), and the adhesive sheet and / or mold are processed into a desired shape (second processing step S17). This produces a fragranced microneedle sheet 1.

[0050] According to the manufacturing method of this embodiment, since the fragrance component is initially attached only to the adhesive sheet, the fragrance component can be evenly applied to the entire adhesive layer. Modifications of the manufacturing method of the above embodiment can be suitably used, especially when manufacturing in large batches.

[0051] In the fragrance component attachment step S11 of the above embodiment, the fragrance component is attached by holding the adhesive sheet inside a housing filled with fragrance components for a certain period of time. However, the fragrance component attachment step S11 may also be performed by directly spraying or applying the fragrance to the adhesive sheet. In this case, it should be noted that the fragrance must be sufficiently volatile so as not to cause skin irritation. [Examples]

[0052] Next, the present invention will be described in more detail with reference to examples, but the present invention is not limited to these examples.

[0053] <Evaluation test on the effects of scented microneedle sheets on the psychological state of users> In this study, scented needle sheets were applied to the mouth area (nasolabial folds) of users, and the effects of the scented microneedle sheets on users were evaluated.

[0054] (Test method) Referring to Table 2, the psychological state (mood) of seven users before and after using the microneedle sheets was evaluated on a 5-point scale from A to I. First, the mood before using the product was evaluated, and then two microneedle sheets were applied to each side of the nasolabial folds for each evaluation test. After application, the users rested for 10 minutes, and then their mood after use was evaluated again on a scale from A to H. This allowed us to evaluate the change in the users' mood before and after using the microneedle sheets for both Example 1 and the Comparative Example. The Example and Comparative Example are as follows. Example 1: Scented microneedle sheet made using lavender fragrance (manufactured by Yamamoto Fragrance Co., Ltd.) Comparative example: Conventional microneedle sheet (without fragrance components)

[0055] [Table 2]

[0056] (Test results) The evaluation results are shown in Figure 4. Figure 4(a) shows the results of evaluating the psychological state of the comparative example before and after using the microneedle sheet for evaluation items A to I. Figure 4(b) shows the results of evaluating the psychological state of Example 1 before and after using the microneedle sheet for evaluation items A to I. Note that each value is the average value of the results from 7 users.

[0057] The evaluation results showed that in Example 1, all users tended to select positive moods for each evaluation item. In particular, the results for evaluation items D, F, and H indicated that the use of the scented microneedle sheet led to a greater tendency for users to feel relaxed, soothed, and calm. Furthermore, evaluation items A, B, C, and E, which did not show much improvement in the comparative example, all showed improvement in mood in Example 1. In other words, it was found that the sheet had the effect of making users feel relaxed, at ease, refreshed, and clear-headed. In addition, for evaluation items G and I, few users tended to select positive moods before use, but after use, the number of users selecting positive moods increased significantly. In other words, it was found that the use of the microneedle sheet in Example 1 had the effect of making users feel refreshed and invigorated.

[0058] Based on the above, it was found that the microneedle sheet according to this embodiment has the effect of enhancing relaxation during sleep and calming the mind, compared to conventional microneedle sheets.

[0059] <Evaluation test on the fragrance persistence of scented microneedle sheets> In this study, the persistence of fragrance was evaluated by storing scented microneedle sheets, removed from a sealed container, at room temperature.

[0060] (Test method) Scented microneedle sheets, which had been kept in a sealed container filled with fragrance components for 5 days, were removed and placed on a desk at room temperature (23°C). After standing for predetermined periods (0 hours, 1 hour, 3 hours, 5 hours, 8 hours, and 24 hours), four users confirmed the intensity of the fragrance of the scented microneedle sheets. The example and evaluation criteria are as follows. Example 2: Scented microneedle sheet made using lavender fragrance (manufactured by Yamamoto Fragrance Co., Ltd.) Example 3: Scented microneedle sheet made using geranium fragrance (manufactured by Yamamoto Fragrance Co., Ltd.)

[0061] Evaluation Criteria 5: I can really smell the fragrance. 4: The fragrance is pleasantly noticeable. 3: Smells pleasant 2: I don't really smell it. 1: I can't smell any fragrance at all.

[0062] (Test results) Figure 5 is a graph showing the evaluation results regarding the fragrance persistence of the microneedle sheet. Figure 5(a) shows the results of the fragrance persistence evaluation for Example 2. Figure 5(b) shows the results of the fragrance persistence evaluation for Example 3. Note that each value is the average of the results from four users.

[0063] The evaluation results showed that both Examples 2 and 3 exhibited good fragrance persistence for at least 5 hours. Furthermore, at 8 hours, the fragrance persisted, although not to the same level as immediately after the start of the evaluation. In addition, a slight fragrance persisted even at 24 hours.

[0064] Here, due to the nature of microneedle sheets being applied to the face, it is common practice to apply them after bathing or washing the face, leave them on while sleeping, allow the active skin-beautifying ingredients of the needle sheet to penetrate into the stratum corneum during sleep, and then remove them upon waking. In other words, it is sufficient for the fragrance to last throughout the night. Considering the results of Examples 1-3 together, the microneedle sheets in this example allow users to feel a pleasant fragrance after 3 hours, enabling them to relax and fall asleep. Furthermore, since the fragrance persists after 8 hours, a more refreshing and invigorating awakening can be expected. This shows that not only can the microneedle sheets provide the skin-beautifying effect they are known for, but they can also be expected to improve the quality of sleep.

[0065] Furthermore, the microneedle sheet of this embodiment allows for appropriate modification of the content or type of fragrance components and effective skin-beautifying components depending on the application. This enables its use in desired applications such as pharmaceuticals, quasi-drugs, medicated cosmetics, and cosmetics.

[0066] The embodiments disclosed herein should be considered in all respects to be illustrative and not restrictive. The scope of the present invention is indicated by the claims rather than by the foregoing description, and all modifications within the meaning and scope equivalent to the claims are intended to be included. [Explanation of symbols]

[0067] 1. Scented microneedle sheet, 2. Adhesive sheet, 3. Needle sheet, 4. Protective plate, 20. Base layer, 21. Adhesive layer, 30. Fine protrusions, A1. Fragrance area, A2. Functional area.

Claims

1. An adhesive sheet comprising a base layer and an adhesive layer, It comprises a needle sheet containing fine protrusions that contain effective skin-beautifying ingredients, The adhesive sheet is a scented microneedle sheet, comprising an aromatic region to which fragrance components are attached and a functional region to which the needle sheet is attached.

2. The scented microneedle sheet according to claim 1, wherein the adhesive sheet and the needle sheet do not contain fragrance.

3. The fragrance component comprises one or more fragrance components selected from the group consisting of linalool, α-pinene, limonene, terpinen-4-ol, α-santalol, geraniol, furanoidesum 1,3-diene, linalyl acetate, isobutyl angelicate, patchouli alcohol, benzyl acetate, carotol, α-himacalene, estragol (methyl chavicol), sabinene, and β-phenethyl alcohol, as described in claim 1 or 2.

4. The scented microneedle sheet according to claim 1 or 2, further comprising a protective plate that protects the fine protrusions at a position opposite one surface of the needle sheet.

5. A step of preparing a mold having fine recesses, The process of filling the mold with the raw material for the needle sheet, A step of drying the mold filled with the aforementioned raw materials, A processing step of processing the dried needle sheet made from the raw material into a desired shape, The process of attaching an adhesive sheet to the needle sheet after the processing step, The process involves processing the adhesive sheet into a desired shape to obtain an untreated microneedle sheet. A method for producing a scented microneedle sheet, comprising the step of attaching fragrance components of a fragrance to at least the adhesive sheet of the untreated microneedle sheet.

6. The process of preparing the adhesive sheet, The process involves attaching fragrance components of the fragrance to the adhesive sheet, A step of preparing a mold having fine recesses, The process of filling the mold with the raw material for the needle sheet, A step of drying the mold filled with the aforementioned raw materials, A processing step of processing the dried needle sheet made from the raw material into a desired shape, The process involves attaching an adhesive sheet to which fragrance components are attached to the needle sheet after the processing step, A method for manufacturing a scented microneedle sheet, comprising the step of processing the adhesive sheet into a desired shape.

7. The method for manufacturing a scented microneedle sheet according to claim 5 or 6, wherein the step of attaching the fragrance components of the fragrance is a step of attaching at least the fragrance components to the adhesive sheet by holding it in a housing filled with the fragrance components of the fragrance for a certain period of time.

8. The method for producing a scented microneedle sheet according to claim 5 or 6, wherein the fragrance includes a fragrance component that adheres to the adhesive sheet.

9. The method for producing a scented microneedle sheet according to claim 5 or 6, wherein the fragrance comprises at least one fragrance selected from the group consisting of lavender, geranium, rosemary, sweet orange, sweet marjoram, grapefruit, sandalwood, bergamot, lemon, frankincense, ylang-ylang, Roman chamomile, clary sage, juniper berry, neroli, rose, carrot seed, cypress, cedarwood, jasmine, basil, patchouli, palmarosa, petitgrain, myrrh, and rosewood.

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