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JP2026094226APending Publication Date: 2026-06-09センテッサ ファーマシューティカルズ (ユーケー) リミテッド
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- センテッサ ファーマシューティカルズ (ユーケー) リミテッド
- Filing Date
- 2026-02-20
- Publication Date
- 2026-06-09
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Figure 2026094226000011 
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Abstract
This invention provides an antibody molecule that specifically binds to CD47 (also known as differentiation cluster 47 or integrin-associated protein [IAP]) and its antigen-binding portion. [Solution] In an embodiment of the present invention, the anti-CD47 antibody molecule and its antigen-binding moiety specifically bind to human CD47 and cynomolgus monkey CD47. The medical use of the anti-CD47 antibody molecule and antigen-binding moiety of the present invention is disclosed. The anti-CD47 antibody molecule and antigen-binding moiety of the present invention are modified and optimized binding molecules compared to the VxP037 mouse / humanized anti-CD47 antibody described in International Publication No. 2014 / 093678A2.
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Claims
[Claim 1] The invention described in the specification.