Consumables data integration management system and platform
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- MESO SCALE TECH LLC
- Filing Date
- 2026-01-08
- Publication Date
- 2026-06-23
AI Technical Summary
【0056】 追加の自動アッセイシステムは、 (a)ほぼ矩形表面に前端、第1の側端、第2の側端、及び後端縁を提供するアッセイ構成要素を保持するための処理デッキであって、 (i)96ウェルアッセイプレートの幅及び長さについてANSI-SLAS仕様を満たす消耗品を保持するサイズに作られた複数の消耗品長穴を有するデッキの前端上でほぼ中心に置かれ、片持ちにされたアッセイ消耗品ホテルと、 (ii)デッキの第1の側に位置するピペット先端容器を保持するための複数のピペット先端場所と、 (iii)デッキの後端縁に沿って位置する複数のプレートシェーカ場所と、 (iv)ホテルと、ANSI-SLASに準拠する寸法を有する消耗品を保持するように構成されるシェーカとの間でデッキのほぼ中心に位置する処理場所のセットと、 (v)ピペット先端場所の後方でデッキの第1の側に位置するバーコードスキャナであって、ANSI-SLASに準拠する寸法を有する消耗品の底面を走査するほど十分に大きい走査表面を有するバーコードスキャナと を支持する該デッキと、 (b)デッキの下に位置し、ピペット場所とアッセイプレート処理場所との間のデッキの開口を通してアクセス可能なプレート洗浄機と、 (c)グリッパが場所(i)から(v)にアクセスするために移動できるようにロボットプレートグリッパを可動で支持し、ピペッタが場所(ii)及び(iv)にアクセスできるようにロボット8チャネルピペッタを可動で支持するデッキ上方に位置するガントリと、 (d)デッキよりもより低い垂直高所であるプラットフォーム上のデッキの第1の側面の隣に位置するアッセイ読取装置であって、読取装置上の最も高い点は、ロボットグラバが移動できる最も低い点よりもより低い、アッセイ読取装置と、 (e)温度制御下で構成要素を維持するための温度コントローラを有し、ユーザにデッキの正面及びその上に位置する消耗品ホテルへのアクセスを提供するドアを有する、構成要素(a)~(d)を取り囲むエンクロージャと、 を含む、自動アッセイシステムに関する。
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Abstract
Claims
1. An assay reading device, The photodetection subsystem and A plate handling subsystem having a light-shielding enclosure is provided, The light-shielding enclosure comprises a housing having an upper housing, a lower housing, a front housing, and a rear housing. The housing further comprises a plurality of alignment features, The housing is adapted to accommodate a removable drawer, The assay reading device is configured to read each well of a plate in a row-to-row reading pattern.
2. The assay reading device according to claim 1, wherein the upper part of the housing comprises one or more plate introduction openings and one or more plate discharge openings, and a plate is lowered onto or removed from a plate translation stage through the plate introduction openings and the plate discharge openings.
3. The assay reading device according to claim 2, further comprising a sliding light-shielding door configured to seal one or more plate introduction openings from ambient light.
4. The assay reading device according to claim 1, wherein the upper part of the housing comprises an identifier controller configured to read and process data associated with an identifier placed on the plate.
5. The assay reading device according to claim 4, wherein the identifier controller is a barcode reader mounted on an opening in the upper part of the housing via a light-shielding seal.
6. The assay reading device according to claim 4, wherein the identifier controller is provided separately from the assay reading device.
7. The assay reader according to claim 4, wherein the identifier controller comprises an electrical connector that enables the transfer of information between the identifier controller and an integrated circuit card configured for insertion into the assay reader.
8. The assay reader according to claim 7, further comprising a contact pad configured to contact the electrical connector of the identifier controller, wherein the integrated circuit card is further a contact pad configured to contact the electrical connector of the identifier controller.
9. The assay reader according to claim 4, wherein the identifier controller is configured to interface with a radio frequency identification (RFID) system.
10. The assay reading device according to claim 1, further comprising one or more photodetectors.
11. The assay reading device according to claim 1, further comprising one or more electrical energy sources for inducing luminescence.
12. The assay reading device according to claim 1, further comprising a thermoelectric cooling device for an optical sensor.
13. The assay reading device according to claim 12, wherein the optical sensor is a charge-coupled element.
14. The assay reading device according to claim 12, wherein the optical sensor is a complementary metal-oxide-semiconductor device.
15. An automated assay system, Robot gripper arm and Plate carrier and Multiple optional heatable shakers, Processing deck and An air cooling processing system comprising one or more thermoelectric cooling devices, An automated assay system comprising one or more thermoelectric cooling devices configured to receive warm air from the processing deck and return cooled air to the processing deck.
16. A method for performing an assay on a multiwell assay plate, The steps include receiving the multiwell assay plate with an assay reader, The steps include reading the consumable identifier associated with the multiwell assay plate, A step of obtaining available consumable data associated with the consumable identifier, including at least an assay protocol, A method comprising the step of initiating one or more manual or automated steps of the assay protocol.
17. A method for performing an assay on an 8x12 multiwell assay plate, The procedure involves using a pipette with eight tips to pipette the reading buffer into the wells of the multi-well assay plate, one row at a time. The steps include inserting the multiwell assay plate into the assay reader, The assay reading device reads the multiwell assay plate in blocks of four wells, and the following steps are included: Each block of the four wells spans two rows and two columns. The reading pattern of the assay reader is a method comprising reading all the wells of a first pair of columns in a first direction, and then reading all the wells of a second pair of columns in a second direction.