Use of mangosteen peel extract in the preparation of compositions for maintaining bone health

A two-stage extraction process for mangosteen peel extract addresses the limitations of current osteoporosis and osteoarthritis treatments by enhancing bone density and joint health through inhibition of osteoclast differentiation and inflammation suppression.

JP2026518056APending Publication Date: 2026-06-03TCI CO LTD(CN)
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
TCI CO LTD(CN)
Filing Date
2024-05-22
Publication Date
2026-06-03

AI Technical Summary

Technical Problem

Current treatments for osteoporosis and osteoarthritis primarily focus on slowing bone loss and reducing joint pain, with limited ability to restore bone structure and joint function, and there is a need for functional foods that can strengthen bones and improve joint health.

Method used

A two-stage extraction process using enzyme solutions at different temperatures to produce mangosteen peel extract, which is then formulated into compositions for maintaining bone health, including functions such as inhibiting osteoclast differentiation, promoting calcium absorption, and suppressing inflammation.

Benefits of technology

The mangosteen peel extract effectively strengthens bones, prevents joint wear, increases bone density, and reduces inflammation, thereby improving bone health and joint function.

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Abstract

The objective is to provide information on the use of mangosteen peel extract in the preparation of compositions for maintaining bone health. [Solution] Mangosteen peel extract is obtained by sequentially extracting the fruit peel of mangosteen (Garcinia mangostana) in two stages using an enzyme solution at different extraction temperatures. This two-stage extraction completely releases and retains the active ingredients in the mangosteen peel, increasing the active ingredient content in the extract. As a result, a variety of functions related to bone health can be expected, such as bone strengthening, prevention of joint wear, suppression of bone loss, improvement of bone density, promotion of calcium absorption, alleviation of inflammation in the body, and prevention of inflammation caused by joint wear.
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