Bone graft composition and method for manufacturing the same

Abstract

This invention relates to a bone graft composition comprising mineral trioxide aggregates (MTA) and a porous synthetic bone graft material. By adding MTA, the bone graft composition of this invention can improve the handling properties of the bone graft composition and form a high-strength structure.

Claims

[Claim 1] A bone graft material composition comprising mineral trioxide aggregates (MTA) and porous synthetic bone graft material. [Claim 2] MTA is tricalcium silicate (C 3 S) and / or dicalcium silicate (C) 2 The bone graft material composition according to claim 1, comprising S). [Claim 3] MTA is tricalcium silicate (C 3 Contains only S, or tricalcium silicate (C) in a weight ratio of 8:2 to 2:

8. 3 S) and dicalcium silicate (C 2 The bone graft material composition according to claim 2, comprising a mixture of S). [Claim 4] The bone graft composition according to claim 1, wherein the porous synthetic bone graft material comprises hydroxyapatite (HA) and / or beta-tricalcium phosphate (β-TCP). [Claim 5] The bone graft material composition according to claim 1, wherein the bone graft material composition comprises porous synthetic bone graft material coarse powder and / or porous synthetic bone graft material fine powder. [Claim 6] The bone graft material composition according to claim 5, wherein the average particle size of the porous synthetic bone graft material coarse powder is 0.1 to 1.0 mm. [Claim 7] The bone graft material composition according to claim 5, wherein the average particle size of the porous synthetic bone graft material fine powder is 0.05 to 0.1 mm. [Claim 8] The bone graft material composition according to claim 4, wherein the porous synthetic bone graft material contains hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP) in a weight ratio of 9:1 to 1:

9. [Claim 9] The bone graft material composition according to claim 1, wherein the bone graft material composition contains 20 to 70 parts by weight of MTA per 100 parts by weight of porous synthetic bone graft material. [Claim 10] The bone graft material composition according to claim 5, wherein the bone graft material composition comprises only porous synthetic bone graft material coarse powder, or comprises a mixture of porous synthetic bone graft material coarse powder and porous synthetic bone graft material fine powder in a weight ratio of 9:1 to 5:

5. [Claim 11] A method for producing a bone graft material composition, (a) A step of preparing a porous synthetic bone graft material having holes; (b) the process of preparing MTA; and (c) A process of mixing porous synthetic bone graft material and MTA to produce a bone graft material composition. Methods that include... [Claim 12] The method according to claim 11, wherein in step (a), the porous synthetic bone graft material is pulverized to have different average particle sizes, thereby producing a porous synthetic bone graft material coarse powder and / or porous synthetic bone graft material fine powder.

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