Compositions and methods for inhibition of lineage-specific antigens - Patents.com
JP7680384B2Active Publication Date: 2025-05-20THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK
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Patent Information
- Application Number
- JP2022010861
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2015-10-16
- Filing Date
- 2022-01-27
- Publication Date
- 2025-05-20
- Estimated Expiration
- 2036-10-17
Abstract
Methods for treating hematopoietic malignancies are provided. [Solution] The method includes administering to a subject (i) an effective amount of an agent that targets a lineage-specific cell surface antigen, wherein the agent comprises an antigen-binding fragment that binds the lineage-specific cell surface antigen, and (ii) a hematopoietic cell population that lacks the lineage-specific cell surface antigen.
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Citation Information
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