Methods for producing secreted proteins

Modified cyanobacteria with reduced outer membrane-cell wall binding facilitate efficient protein secretion and reuse, addressing inefficiencies in conventional protein production methods.

JP7766262B2Active Publication Date: 2025-11-10PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO LTD
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Patent Information

Application Number
JP2021558356
Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
Priority Date
2019-11-21
Filing Date
2020-11-16
Publication Date
2025-11-10
Estimated Expiration
2040-11-16

AI Technical Summary

Technical Problem

Conventional methods for producing proteins using cyanobacteria are inefficient due to low protein recovery rates and the need to disrupt bacterial cells, which increases production costs and time.

Method used

Modified cyanobacteria with suppressed or lost function of proteins involved in binding between the outer membrane and the cell wall, allowing partial detachment and extracellular secretion of proteins, eliminating the need for cell disruption.

Benefits of technology

Enhances protein secretion productivity and allows continuous use of modified cyanobacteria for protein production, improving efficiency and reducing production costs.

✦ Generated by Eureka AI based on patent content.

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Patent Text Reader

Abstract

The function of a protein that contributes to binding with an outer membrane (5) and a cell wall (4) in a cyanobacteria is suppressed or lost in this modified cyanobacteria.
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Citation Information

Patent Citations

  • Variable capacity compressor

    JP1988041676A

  • Method for producing useful material such as biofuel by using cyanobacterium having auto-bacteriolytic ability

    JP2015109828A