Absorbent article having odor control composition

Abstract

Disposable absorbent articles are described that have a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet. The disposable absorbent articles include an odor control composition that has a preservative, a surfactant, methylated beta-cyclodextrin (m-BCD), and a fragrance.

Description

[Technical Field]

[0001] FIELD OF THE INVENTION This application relates generally to absorbent articles containing improved odor control compositions and methods of making the same. [Background technology]

[0002] The use of feminine hygiene pads to absorb body exudates has been known for decades. Improvements over the years have addressed the softness / feel of the pads against the wearer's skin, as well as the fluid acquisition rate, fluid acquisition retention, and / or fluid capacity of these pads. Another area of ​​improvement in feminine hygiene pads is in the area of ​​odor control.

[0003] Odor control compositions for feminine pads are utilized to combat odors generated by the breakdown of menstrual fluid and / or urine. While these odor control compositions have proven effective in combating such odors, unfortunately, their application to feminine hygiene pads can be quite complicated.

[0004] Many odor control compositions are described as being applied via a solvent carrier. The solvent carrier allows the composition to dry easily on the feminine hygiene article. However, these solvents can increase the complexity of feminine hygiene pad manufacturing. For example, evaporated solvents often need to be absorbed / reduced by volatile organic compound abatement systems. These systems can be expensive and overly complicated to operate. In addition, these solvents, especially their vapors, can be flammable. This can increase the risk of fire. Summary of the Invention [Problem to be solved by the invention]

[0005] Based on the above, there is a need for an odor control composition that does not require a solvent carrier and that is easy to apply to feminine hygiene pads. [Means for solving the problem]

[0006] The disposable absorbent articles of the present disclosure can provide protection from odors caused by body exudates absorbed onto the absorbent article. In one particular example, the disposable absorbent article comprises a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet, and the disposable absorbent article further comprises an odor control composition comprising a preservative, a surfactant, methylated β-cyclodextrin (m-BCD), and a fragrance. [Brief explanation of the drawings]

[0007] While this specification concludes with claims particularly pointing out and distinctly claiming the subject matter regarded as the invention, it is believed that the invention will be better understood from the following description read in conjunction with the accompanying drawings. Some of the figures may be simplified by omitting selected elements for the purpose of more clearly showing other elements. The omission of such elements in some of the figures does not necessarily indicate the presence or absence of the particular element in any of the illustrative embodiments, unless expressly depicted in the corresponding written description. None of the drawings are necessarily to scale. [Figure 1] 1 is a graph showing representative chromatograms of hydrolyzed, reduced, and acetylated methyl β-cyclodextrin. [Figure 2] 1 is a schematic diagram of an absorbent article. DETAILED DESCRIPTION OF THE INVENTION

[0008] As used herein, the following terms shall have the meanings specified below. "Absorbent article" refers to a wearable device that absorbs and / or contains liquids, and more particularly, to a device that is placed against or adjacent to the body of a wearer to absorb and contain various bodily exudates. Absorbent articles can include diapers, training pants, adult incontinence undergarments (e.g., liners, pads, and briefs), and / or feminine hygiene products.

[0009] "ClogP" refers to the calculated logP value, which is a measure of the hydrophilicity of a compound, where logP is the octanol / water partition coefficient calculated by the Consensus algorithm implemented in version 14.02 of ACD / Percepta by Advanced Chemistry Development, Inc. (ACD / Labs, Toronto, Canada).

[0010] "Complex" shall mean an "inclusion complex" within the meaning of the IUPAC Compendium of Chemical Terminology, 2nd Edition (1997), in which the complexing agent (in this case, cyclodextrin) is the host and the complexed component is the "guest."

[0011] "Cyclodextrin complex" refers to a complex of cyclodextrin and fragrance.

[0012] "Cyclodextrin complex stability constant" or "complex stability constant" (log K) refers to the ability of a perfume raw material to bind to cyclodextrin. Complex stability constants of numerous materials with various cyclodextrins, as measured by calorimetry, can be found in the literature, for example, Rekharsky and Inoue (1998), Complexation Thermodynamics of Cyclodextrins, Chemical Review, 98, 1875-1917. Additionally, for reference, the following table contains a list of perfume raw materials and their estimated complex stability constants:

[0013] "Molecular weight," unless otherwise specified, refers to the weight average molecular weight, which can be calculated by using the sum of the molecular weights of the elements in the molecule. These can be found, for example, in Atomic Weights of the Elements, Weiser, 2005.

[0014] "Odor detection threshold" refers to the lowest concentration in air of a particular odorous compound that is perceptible to the human sense of smell. The odor detection thresholds for many materials can be found in van Gemert, LJ; Odor Thresholds (Compilations of Odor Threshold Values ​​in Air, Water and Other Media; Oliemans Punter & Partners; The Netherlands, 2011). Odor detection thresholds are in units of -log molar concentration. In this context, the human odor detection threshold (ODT) is expressed as an olfactory power, or p.ol (the negative logarithm of the molar concentration of an odorant in air at which a human first detects its presence). These values ​​can be directly converted to other commonly used units, such as ppm (volume) and ppb (volume), with thresholds of 1 ppm and 1 ppb being equivalent to p.ol = 6 and p.ol = 9, respectively. Odor detection thresholds can be measured, for example, by the method of WO 2006 / 138726.

[0015] The odor control composition of the present disclosure is an aqueous composition containing methylated beta cyclodextrin (mBCD), a cyclodextrin-compatible surfactant, a preservative, and a fragrance. The odor control composition of the present disclosure allows for reduced manufacturing complexity and reduced application risks during manufacturing. Furthermore, the inventors have surprisingly discovered that the odor control composition of the present disclosure provides better stability for disposable absorbent articles. It has been discovered that disposable absorbent articles containing a visual signal (a colorant disposed on a layer of the disposable absorbent article) and a conventional odor control composition are susceptible to changes in appearance of the visual signal due to the odor control composition. However, with the odor control composition of the present disclosure, the visual signal remains intact even over time. Furthermore, it has also been discovered that conventional odor control compositions have a similar adverse effect on inks disposed on packaging materials. For example, inks disposed on the consumer-facing surface of packaging materials may change in appearance due to the presence of a conventional odor control composition on an article within the packaging material.

[0016] Cyclodextrin-compatible surfactants The surfactant compatible with cyclodextrin provides a low surface tension that allows the composition to spread easily and more uniformly on hydrophobic surfaces. It has been found that aqueous solutions without such surfactants do not spread well. Spreading the composition also allows the composition to dry more quickly, so that the treated material is ready for immediate use.

[0017] Surfactants for use in providing the low surface tension required in the compositions of the present invention should be compatible with cyclodextrin. That is, the surfactant should not substantially complex with the cyclodextrin, thereby reducing the performance of the cyclodextrin and / or the surfactant. Complexation reduces both the amount of cyclodextrin available to release fragrance and the surfactant's ability to reduce the surface tension of an aqueous composition. Suitable cyclodextrin-compatible surfactants can be readily identified by the lack of effect of the cyclodextrin on the surface tension provided by the surfactant. This is achieved by measuring the surface tension (in dynes / cm) of an aqueous solution of the surfactant in the presence and absence of approximately 1% of a particular cyclodextrin in the solution. 2 This is achieved by measuring the surface activity of the surfactant (at 0.5%, 0.1%, 0.01%, and 0.005%). The aqueous solutions contain surfactants at concentrations of about 0.5%, 0.1%, 0.01%, and 0.005%. Cyclodextrin can affect the surface activity of surfactants by increasing the surface tension of the surfactant solution. If the surface tension at a given concentration in water differs by more than about 10% from the surface tension of the same surfactant in a 1% solution of cyclodextrin, it is an indication of a strong interaction between the surfactant and cyclodextrin. Preferred surfactants herein should have a (low) surface tension in aqueous solution that differs by less than about 10%, preferably less than about 5%, and more preferably less than about 1% from the surface tension of a solution of the same concentration containing 1% cyclodextrin.

[0018] Non-limiting examples of nonionic surfactants compatible with cyclodextrins include block copolymers of ethylene oxide and propylene oxide. Suitable block polyoxyethylene polyoxypropylene polymer surfactants that are compatible with most cyclodextrins include those based on ethylene glycol, propylene glycol, glycerol, trimethylolpropane, and ethylenediamine as the initial reactive hydrogen compound. Polymeric compounds made by sequential ethoxylation and propoxylation of the initial compound with a single reactive hydrogen atom, such as a C12-18 aliphatic alcohol, are generally not compatible with cyclodextrins.

[0019] Certain block polymer surfactant compounds designated Pluronic® and Tetronic® by BASF-Wyandotte Corp. (Wyandotte, Mich.) are readily available. Non-limiting examples of this type of cyclodextrin-compatible surfactant include Pluronic surfactants having the general formula: H(EO)n(PO)m(EO)nH, where EO is an ethylene oxide group, PO is a propylene oxide group, and n and m are numbers representing the average number of groups in the surfactant.

[0020] Typical examples of Pluronic surfactants compatible with cyclodextrins are listed in Table 1.

[0021] [Table 1] as well as mixtures thereof.

[0022] General formula:

[0023] [ka] (wherein EO, PO, n, and m have the same meanings as above). Typical examples of Tetronic surfactants compatible with cyclodextrins are shown in Table 2.

[0024] [Table 2] as well as mixtures thereof.

[0025] "Reverse" Pluronic and Tetronic surfactants have the following general formula: Reverse Pluronic surfactant: H(PO)m(EO)n(PO)mH, Reverse Tetronic surfactant:

[0026] [ka] (wherein EO, PO, n, and m have the same meanings as above).

[0027] Typical examples of cyclodextrin compatible Reverse Pluronic and Reverse Tetronic surfactants are: Table 3 Reverse Pluronic Surfactants:

[0028] [Table 3] Table 4 Reverse Tetronic Surfactants:

[0029] [Table 4] as well as mixtures thereof.

[0030] A preferred class of cyclodextrin-compatible nonionic surfactants are the polyalkylene oxide polysiloxanes having a dimethylpolysiloxane hydrophobic portion and one or more hydrophilic polyalkylene side chains, and having the general formula: R1 -(CH3)2SiO-[(CH3)2SiO]a[(CH3)(R 1 )SiO]b-Si(CH3)2-R 1 In the formula, a+b is about 1 to about 50, preferably about 3 to about 30, more preferably about 10 to about 25, each R1 is the same or different, and is selected from methyl and the general formula: -(CH2) n O(C2H4O) c (C3H6O) d R 2 wherein at least one R1 is a poly(ethylene oxide / propylene oxide) copolymer group having the formula: 2 are the same or different and are selected from the group consisting of hydrogen, alkyl having 1 to 4 carbon atoms, and acetyl groups, and are preferably hydrogen and methyl groups.

[0031] Examples of this type of surfactant are Silwet® surfactants available from OSi Specialties, Inc., Danbury, Conn. Representative Silwet surfactants are listed in Table 5.

[0032] [Table 5]

[0033] Polyalkyleneoxy group (R 1The molecular weight of the polyalkyleneoxy group is about 10,000 or less. Preferably, the molecular weight of the polyalkyleneoxy group is about 8,000 or less, and most preferably in the range of about 300 to about 5,000. Therefore, the values ​​of c and d can be numbers that provide a molecular weight within these ranges. However, the molecular weight of the polyether chain (R 1 The number of ethyleneoxy units (—CHO) in the propyleneoxy group should be sufficient to render the polyalkyleneoxide polysiloxane water-dispersible or water-soluble. When propyleneoxy groups are present in the polyalkyleneoxide chain, they may be randomly distributed in the chain or present as blocks. Preferred Silwet surfactants are L-7600, L-7602, L-7604, L-7605, L-7657, and mixtures thereof. In addition to surface activity, polyalkyleneoxide polysiloxane surfactants can also impart other benefits to fabrics, such as antistatic effects, lubricity, and softness. The preparation of polyalkyleneoxide polysiloxanes is well known in the art. The polyalkyleneoxide polysiloxanes of the present invention can be prepared according to the procedure described in U.S. Pat. No. 3,299,112, incorporated herein by reference. Typically, the polyalkylene oxide polysiloxanes of the surfactant blends of the present invention are readily prepared by the addition reaction between a hydrosiloxane (i.e., a siloxane containing silicon-bonded hydrogen) and an alkenyl ether (e.g., vinyl, allyl, or methallyl ether) of an alkoxy or hydroxy endblocked polyalkylene oxide. The reaction conditions used in this type of addition reaction are well known in the art and generally involve heating the reactants (e.g., at a temperature of about 85°C to 110°C) in the presence of a platinum catalyst (e.g., chloroplatinic acid) and a solvent (e.g., toluene).

[0034] Non-limiting examples of cyclodextrin-compatible anionic surfactants include those having the general formula:

[0035] [ka] where R is an alkyl group. An example of this type of surfactant is available from The Dow Chemical Company under the trade name Dowfax®, where R is a linear or branched C6-C16 alkyl group. An example of an anionic surfactant compatible with these cyclodextrins is Dowfax 3B2, where R is approximately a linear C10 group. These anionic surfactants are preferably not used when using cationic antimicrobial actives or preservatives, as this minimizes interaction with the cationic actives, as this reduces the effectiveness of both the surfactant and the active. The above surfactants either interact weakly (less than a 5% increase in surface tension) or do not interact (less than a 1% increase in surface tension) with cyclodextrin. Common surfactants such as sodium dodecyl sulfate and dodecanol poly(6) ethoxylate interact strongly, increasing the surface tension by more than 10% in the presence of typical cyclodextrins such as hydroxypropyl β-cyclodextrin and methylated β-cyclodextrin.

[0036] Typical concentrations of cyclodextrin-compatible surfactant in use compositions are from about 0.01% to about 2%, preferably from about 0.03% to about 0.6%, and more preferably from about 0.05% to about 0.3% by weight of the composition (specifically, all values ​​within these ranges and any ranges created by these values ​​are recited).

[0037] preservatives The odor control composition further comprises a water-soluble antimicrobial preservative. As previously mentioned, cyclodextrin molecules are composed of varying numbers of glucose units, which can make them a prime breeding ground for certain microorganisms, especially when present in aqueous compositions. This drawback can lead to storage stability issues for cyclodextrin solutions over any significant period of time. Contamination by certain microorganisms and subsequent microbial growth can result in an unsightly and / or foul-smelling solution. Because microbial growth in cyclodextrin solutions can be very unpleasant, it is highly preferred to include a solubilized, water-soluble antimicrobial preservative that is effective in inhibiting and / or controlling microbial growth in order to increase the storage stability of a preferably clear, aqueous odor-absorbing solution containing water-soluble cyclodextrin.

[0038] It is preferable to use a broad-spectrum preservative, e.g., one that is effective against both bacteria (both gram-positive and gram-negative) and fungi. Narrow-spectrum preservatives, e.g., preservatives that are effective only against a single group of microorganisms, e.g., fungi, can be used in combination with broad-spectrum preservatives or other narrow-spectrum preservatives with complementary and / or supplementary activity. Mixtures of broad-spectrum preservatives can also be used. In some cases where a specific group of microbial contaminants is a problem (e.g., gram-negative), aminocarboxylate chelating agents may be used as enhancers, alone or in combination with other preservatives. For example, chelating agents including ethylenediaminetetraacetic acids (EDTA), hydroxyethylenediaminetriacetic acid, diethylenetriaminepentaacetic acid, and other aminocarboxylate chelating agents, as well as mixtures thereof, and salts thereof, can enhance preservative effectiveness against gram-negative bacteria, particularly Pseudomonas species. Antimicrobial preservatives useful in the odor compositions of the present disclosure include biocidal compounds, i.e., substances that kill microorganisms, or bacteriostatic compounds, i.e., substances that inhibit and / or regulate the growth of microorganisms. Because organic preservatives can form inclusion complexes with cyclodextrin molecules and compete with fragrance molecules for the cyclodextrin cavity, thereby limiting the amount of cyclodextrin available for fragrance release, preferred antimicrobial preservatives are water-soluble and effective at low levels. Water-soluble preservatives useful in the present invention have a water solubility of at least about 0.3 g per 100 mL of water, i.e., greater than about 0.3% at room temperature, preferably greater than about 0.5% at room temperature. These types of preservatives have a lower affinity for the cyclodextrin cavity, at least in the aqueous phase, and are therefore more available to provide antimicrobial activity. Preservatives with a water solubility of less than about 0.3% and a molecular structure that easily fits into the cyclodextrin cavity have a greater tendency to form inclusion complexes with cyclodextrin molecules, thereby reducing the effectiveness of the preservative for controlling microorganisms in cyclodextrin solutions.Thus, many well-known preservatives, such as short-chain alkyl esters of p-hydroxybenzoic acid, commonly known as parabens; N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)urea, also known as 3,4,4'-trichlorocarbanilide or triclocarban; and 2,4,4'-trichloro-2'-hydroxydiphenyl ether, commonly known as triclosan, are relatively ineffective when used with cyclodextrins and are therefore not preferred in the odor control compositions of the present disclosure.

[0039] The water-soluble preservative in the odor control composition of the present disclosure is present in an effective amount. As defined herein, the term "effective amount" refers to a level sufficient to prevent spoilage or the growth of inadvertently added microorganisms for a specified period of time. In other words, the preservative is not used to kill microorganisms on the surface onto which the composition is deposited in order to mask odors caused by the microorganisms. Rather, the preservative is preferably used to prevent spoilage of the cyclodextrin solution in order to extend the shelf life of the composition.

[0040] A preferred concentration of preservative is about 0.5% to about 1.0% by weight of the use composition, more preferably 0.5% to about 0.9% by weight, and most preferably about 0.5% to about 0.8% by weight (specifically, all values ​​within these ranges and any ranges created by these values ​​are recited). Without being bound by theory, it is believed that below about 0.5% by weight of preservative, unacceptable levels of microbial growth may occur. Furthermore, above about 1.0%, it is believed that the benefit obtained from the added preservative is significantly reduced.

[0041] To preserve the majority of the cyclodextrin for odor control, the molar ratio of cyclodextrin to preservative should be greater than about 5:1, preferably greater than about 10:1, more preferably greater than about 50:1, and even more preferably greater than about 100:1. The preservative can be any organic preservative material that does not cause damage by discoloration, staining, or bleaching to any layer of the absorbent article, such as the topsheet, secondary topsheet, absorbent core, backsheet, etc. Preferred water-soluble preservatives include organic sulfur compounds, halogenated compounds, cyclic organic nitrogen compounds, low molecular weight aldehydes, quaternary ammonium compounds, dehydroacetic acid, phenyl compounds, and phenolic compounds, and mixtures thereof.

[0042] The following are non-limiting examples of water-soluble preservatives that are preferred for use in the odor control compositions of the present disclosure.

[0043] (A).Organic sulfur compounds Preferred water-soluble preservatives for use in the present invention are organosulfur compounds. Some non-limiting examples of organosulfur compounds suitable for use in the present invention are (i) and (ii) below:

[0044] (i) 3-Isothiazolone compounds Preferred preservatives are those of the formula:

[0045] [ka] wherein Y is an unsubstituted alkyl, alkenyl, or alkynyl group of from about 1 to about 18 carbon atoms, an unsubstituted or substituted cycloalkyl group having from about 3 to about 6 carbon rings and up to 12 carbon atoms, an unsubstituted or substituted aralkyl group of up to about 10 carbon atoms, or an unsubstituted or substituted aryl group of up to about 10 carbon atoms; R 1 is hydrogen, halogen, or a (C1-C4) alkyl group; R 2is hydrogen, halogen, or a (C1-C4) alkyl group. Preferably, when Y is methyl or ethyl, R 1 and R 2 cannot both be hydrogen.

[0046] Also suitable are salts of these compounds formed by reacting the compounds with acids such as hydrochloric acid, nitric acid, sulfuric acid, etc. Compounds of this class are disclosed in U.S. Patent No. 4,265,899 (Lewis et al., issued May 5, 1981), which is incorporated herein by reference. Examples of such compounds are 5-chloro-2-methyl-4-isothiazolin-3-one, 2-n-butyl-3-isothiazolone, 2-benzyl-3-isothiazolone, 2-phenyl-3-isothiazolone, 2-methyl-4,5-dichloroisothiazolone, 5-chloro-2-methyl-3-isothiazolone, 2-methyl-4-isothiazolin-3-one, and mixtures thereof. A preferred preservative is a water-soluble mixture of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, more preferably a mixture of about 77% 5-chloro-2-methyl-4-isothiazolin-3-one and about 23% 2-methyl-4-isothiazolin-3-one, a broad-spectrum preservative available as a 1.5% aqueous solution under the trade name Kathon® CG from Rohm and Haas Company. Other isothiazolins include 1,2-benzisothiazolin-3-one, available under the trade name Proxel® products, and 2-methyl-4,5-trimethylene-4-isothiazolin-3-one, available under the trade name Promexal®. Both Proxel and Promexal are available from Zeneca. They are stable over a wide pH range (i.e., 4-12). These preservatives do not contain active halogens and do not release formaldehyde.

[0047] (ii) Sodium pyrithione Another preferred organic sulfur preservative is sodium pyrithione, which has a water solubility of about 50%. Mixtures of preferred organic sulfur compounds may also be used as preservatives in the present invention.

[0048] (B) Halogenated compounds Preferred preservatives for use in the present invention are halogenated compounds. Some non-limiting examples of halogenated compounds suitable for use in the odor control compositions of the present disclosure include 5-bromo-5-nitro-1,3-dioxane, available from Henkel under the trade name Bronidox L®. Bronidox L® has a solubility of about 0.46% in water; 2-bromo-2-nitropropane-1,3-diol, available from Inolex under the trade name Bronopol®, has a solubility of about 25% in water; and 1,1'-hexamethylenebis(5-(p-chlorophenyl)biguanide), commonly known as chlorhexidine, and its salts with, for example, acetic acid and gluconic acid, can be used as preservatives in the odor control compositions of the present disclosure. The digluconate salt has a high water solubility of about 70% in water, and the diacetate salt has a solubility of about 1.8% in water. Another suitable preservative is 1,1,1-trichloro-2-methylpropan-2-ol, commonly known as chlorobutanol, which has a water solubility of about 0.8%; 4,4'-(trimethylenedioxy)bis-(3-bromobenzamidine) diisethionate, i.e., dibromopropamidine, which has a water solubility of about 50%; or a mixture thereof.

[0049] (C).Cyclic organic nitrogen compound Preferred water-soluble preservatives for use in the odor control compositions of the present disclosure are cyclic organic nitrogen compounds. Some non-limiting examples of cyclic organic nitrogen compounds suitable for use in the present invention are (i) and (ii) below:

[0050] (i) Imidazolidinedione compounds Preferred preservatives for use in the odor control compositions of the present disclosure are imidazolidinone compounds. Some non-limiting examples of imidazolidinone compounds suitable for use in the present invention include 1,3-bis(hydroxymethyl-1)-5,5-dimethyl-2,4-imidazolidinedione, commonly known as dimethyloldimethylhydantoin, or DMDM ​​hydantoin, available from Lonza under the trade name Glydant®. DMDM ​​hydantoin has a solubility of greater than 50% in water and is primarily effective against bacteria. When DMDM ​​hydantoin is used, it is preferably used in combination with a broad-spectrum preservative, such as Kathon CG®, or formaldehyde. A preferred mixture is a mixture of approximately 95:5 DMDM ​​hydantoin to 3-butyl-2-iodopropynyl carbamate, available from Lonza under the trade name Glydant Plus®. N-[1,3-bis(hydroxymethyl)2,5-dioxo-4-imidazolidinyl]-N,N'-bis(hydroxymethyl)urea, commonly known as diazolidinyl urea, available from Sutton Laboratories, Inc. (Sutton) under the trade name Germall II®, can be used as a preservative in the odor control compositions of the present disclosure. For example, N,N"-methylenebis{N'-[1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]urea}, commonly known as imidazolidinyl urea, available from 3V-Sigma under the trade name Abiol®, from Induchem under the trade name Unicide U-13®, from Sutton under the trade name Germall 115®, or mixtures thereof, can be used as a preservative in the odor control compositions of the present disclosure.

[0051] (ii) Polymethoxybicyclic oxazolidine Another preferred water-soluble cyclic organic nitrogen preservative has the general formula:

[0052] [ka] wherein n has a value of from about 0 to about 5, and is a polymethoxybicyclic oxazolidine available from Huls America under the tradename Nuosept® C. Mixtures of preferred cyclic organic nitrogen compounds may also be used as preservatives in the odor control compositions of the present disclosure.

[0053] (D) Low molecular weight aldehydes (i) Formaldehyde A preferred preservative for use in the odor control compositions of the present disclosure is formaldehyde, a broad spectrum preservative commonly available as formalin, a 37% solution of formaldehyde in water.

[0054] (ii) Glutaraldehyde A preferred preservative for use in the odor control compositions of the present disclosure is glutaraldehyde, a water-soluble, broad-spectrum preservative commonly available as a 25% or 50% aqueous solution.

[0055] (E).Quaternary compounds Preferred preservatives for use in the present invention are cationic and / or quaternary compounds, including polyaminopropyl biguanide, also known as polyhexamethylene biguanide, having the general formula: HCl·NH2-(CH2)3-[-(CH2)3-NH-C(=NH·HC1)-NH-(CH2)3-] x -(CH2)3-NH-C(=NH)-NH CN

[0056] Polyaminopropyl biguanide is a water-soluble, broad-spectrum preservative available as a 20% aqueous solution available from ICI Americas, Inc., under the trade name Cosmocil CQ®, or from Brooks, Inc., under the trade name Mikrokill®. For example, 1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride, available from Dow Chemical under the trade name Dowicil 200, is an effective quaternary ammonium preservative that is readily soluble in water, but is less preferred due to its tendency to discolor (yellowing).

[0057] Mixtures of preferred quaternary ammonium compounds may also be used as preservatives in the odor control compositions of the present disclosure.

[0058] (F) Dehydroacetic acid A preferred preservative for use in the present invention is dehydroacetic acid. Dehydroacetic acid is a broad spectrum preservative, preferably in the form of its sodium or potassium salt, so that it is water soluble. This preservative acts as a bacteriostatic rather than a biocidal preservative.

[0059] (G) Phenyl and phenolic compounds Some non-limiting examples of phenyl and phenolic compounds suitable for use in the odor control compositions of the present disclosure are 4,4'-diamidino-α,ω-diphenoxypropane diisethionate, commonly known as propamidine isethionate, and 4,4'-diamidino-α,ω-diphenoxyhexane diisethionate, commonly known as hexamidine isethionate, which have a water solubility of about 16%. Another example is benzyl alcohol, which has a water solubility of about 4%.

[0060] Additional preservatives suitable for the compositions of the present disclosure have the following structure (I): HO-CH2-CH2-R (I) wherein R is a substituted or unsubstituted phenyl group, or a substituted or unsubstituted phenoxy group. For example, R may be either an unsubstituted phenyl group or an unsubstituted phenoxy group. Mixtures of compounds represented by structure (I) may also be used.

[0061] Thus, either or both of 2-phenoxyethanol, which has a water solubility of about 2.67%, and 2-phenylethanol, which has a water solubility of about 2%, can be used as preservatives in the compositions of the present disclosure. 2-Phenoxyethanol is also known as ethylene glycol phenyl ether, ethylene glycol monophenyl ether, and 1-hydroxy-2-phenoxyethane, and is available from various commercial sources as DOWANOL PhE, DOWANOL EPh, or DOWANOL EP. 2-Phenylethanol is also known as phenylethanol, 2-phenylethan-1-ol, phenethyl alcohol, β-hydroxyethylbenzene, phenylethyl alcohol, β-phenylethanol, and benzyl carbinol, and is available from various commercial sources.

[0062] (H) Mixtures of these The preservatives of the present invention can be used in mixtures to control a wide range of microorganisms. For aqueous compositions, bacteriostatic effects can be achieved by adjusting the composition pH to an acidic pH, e.g., less than about pH 4, preferably less than about pH 3, or to a basic pH, e.g., greater than about 10, preferably greater than about 11. Low pH for microbial control is not a preferred approach in the present invention because low pH can cause chemical degradation of cyclodextrin. High pH for microbial control is also undesirable because at high pH (e.g., greater than about 10, preferably greater than about 11), cyclodextrins can become ionized, reducing their ability to complex with organic materials. Therefore, aqueous compositions of the odor control compositions of the present disclosure should have a pH of about 3 to about 10, preferably 5, about 4 to about 8, and more preferably about 4.5 to about 6. The pH can be adjusted with inorganic molecules to minimize complexation with cyclodextrin.

[0063] fragrance composition The odor control composition of the present disclosure also includes a fragrance composition. The fragrance composition includes a fragrance raw material that can be provided in a carrier. The carrier can be any suitable material, including dipropylene glycol and isopropyl myristate. However, the inventors have surprisingly found that the use of dipropylene glycol as a carrier can adversely affect the visual signal on the absorbent article over time and / or the ink disposed on the consumer-facing surface of the packaging material in which the absorbent article is placed. In contrast, the inventors have surprisingly found that isopropyl myristate does not have the same effect. Therefore, isopropyl myristate can be used as a carrier for the fragrance composition raw material.

[0064] At least a portion of the perfume raw materials may have a complex stability constant of about 3.0 or less, about 2.5 or less, about 2.0 or less, about 1.0 or less, up to about 0, up to about -1, up to about -2, or any combination thereof. A portion of the perfume raw materials may have a ClogP of about 2.5 or less, about 2.0 or less, about 1.5 or less, about 1.0 or less, up to about -3. A portion of the perfume raw materials may have a weight average molecular weight of about 200 Daltons or less, about 180 Daltons or less, about 150 Daltons or less, about 100 Daltons or less, or up to about 50 Daltons. The perfume raw materials have an odor detection threshold. At least a portion of the perfume raw materials in the perfume composition have an odor detection threshold of about 7-log molar or greater, about 8-log molar or greater, about 9-log molar or greater, up to about 11.5-log molar.

[0065] The perfume composition comprises at least about 10% by weight of the perfume of perfume raw materials having a complex stability constant of about 3.0 or less, a ClogP of about 2.5 or less, and a weight-average molecular weight of about 200 Daltons or less. Going further, the perfume composition comprises at least about 20%, at least about 30%, at least about 40%, or at least about 50%, up to 100%, of perfume raw materials having a complex stability constant of about 3.0 or less, a ClogP of about 2.5 or less, and a weight-average molecular weight of about 200 Daltons or less. In addition, the perfume composition may also comprise perfume raw materials having an odor detection threshold of about 7-log molar. A representative, non-limiting list of perfume raw materials having a complex stability constant of about 3.0 or less, a ClogP of about 2.5 or less, and a weight-average molecular weight of about 200 Daltons or less is shown in Table 6 below.

[0066] [Table 6-1]

[0067] [Table 6-2]

[0068] [Table 6-3]

[0069] [Table 6-4]

[0070] [Table 6-5]

[0071] [Table 6-6]

[0072] [Table 6-7]

[0073] One group of perfume raw materials having a complex stability constant of about 3.0 or less, a ClogP of about 2.5 or less, and a weight average molecular weight of about 200 Daltons or less includes βγ hexanol, cis3 hexenyl acetate, ethyl-2-methyl butyrate, amyl acetate (isomer blend), vanillin, anethole, methyl isoeugenol, guaiacol, floralol; ethyl vanillin, 2,6-nonadien-1-ol, coumarin, and combinations thereof.

[0074] Another group of perfume raw materials having a complex stability constant of about 3.0 or less, a ClogP of about 2.5 or less, and a weight average molecular weight of about 200 Daltons or less includes ethyl-2-methyl butyrate, beta-gamma hexanol, isoamyl acetate, amyl acetate, cis-3-hexenyl acetate, gamma-octalactone, ethyl vanillin, vanillin, benzaldehyde, and combinations thereof. A further group of perfume raw materials having a complex stability constant of about 3.0 or less, a ClogP of about 2.5 or less, and a weight average molecular weight of about 200 Daltons or less includes dimethyl anthranilate, isoeugenyl acetate, canthoxal, 3,6-nonadien-1-ol, triplal, and combinations thereof. Examples include ethyl-2-methyl butyrate, βγ-hexanol, isoamyl acetate, amyl acetate, cis-3-hexenyl acetate, γ-oclatactone, ethyl vanillin, vanillin, and benzaldehyde.

[0075] Some examples of perfume ingredients with odor detection thresholds of 7-log ppb or greater can be found in the table above.

[0076] The perfume may be present in the odor control compositions of the present disclosure in an amount of about 3% by weight or greater, or more preferably about 4% by weight or greater (specifically, all values ​​within these ranges and any ranges created by these values ​​are recited). For example, the perfume may be present in an amount of about 3% by weight to about 6% by weight, or more preferably about 4% by weight to about 6% by weight (specifically, all values ​​within these ranges and any ranges created by these values ​​are recited).

[0077] Without being bound by theory, it is believed that perfumes below about 4% by weight may not provide the desired level of odor control in articles during use. Also, it is believed that perfumes described herein above about 6% by weight may not be completely encapsulated by the substituted cyclodextrin. For example, if it is desired to produce very low or no perfume bloom to the user when the absorbent article is first removed from its packaging, a perfume level of about 6% by weight or less may be beneficial. With the weight percentages of the substituted cyclodextrins disclosed herein, it is believed that perfume levels below about 6% may be substantially, if not completely, encapsulated by the substituted cyclodextrin.

[0078] However, perfume levels greater than about 6% by weight may be utilized if it is desired to provide the user with an initial bloom of perfume prior to use of the absorbent article and additional bloom upon activation (wetting) of the substituted cyclodextrin. It is believed that weight percentage levels greater than about 10.4% by weight may be excessively strong, as approximately 40% of the perfume in the aqueous odor control composition may not be encapsulated. It is believed that greater than about 40 percent unencapsulated perfume results in an initial bloom of strong scent in the disposable absorbent article.

[0079] Regiospecifically substituted cyclodextrins The odor control compositions of the present disclosure include cyclodextrin complexes (hereinafter "substituted cyclodextrin complexes"), which are regiospecifically substituted cyclodextrins containing one or more odor control compounds. The regiospecifically substituted cyclodextrins described herein include various degrees of substitution at the 2-, 3-, and 6-positions. As described herein, regiospecifically substituted cyclodextrins having substitutions at the 2- and 6-positions offer advantages over conventional β-cyclodextrins and fully substituted cyclodextrins (i.e., full substitution at the 2-, 3-, and 6-positions). There are many advantages to utilizing regiospecifically substituted cyclodextrins. For example, regiospecifically substituted cyclodextrins have higher solubility than their conventional β-cyclodextrin counterparts. Increased solubility can result in more rapid release of fragrances encapsulated in the regiospecifically substituted cyclodextrins. Increased solubility also means that less water is required to dissipate fragrances encapsulated in the regiospecifically substituted cyclodextrins. This increased solubility may also mean that less of the regiospecifically substituted cyclodextrin can be utilized in absorbent articles than its β-cyclodextrin counterpart.

[0080] Because of the increased solubility of regiospecifically substituted cyclodextrins, there are application methods for regiospecifically substituted cyclodextrins that are not available for their conventional β-cyclodextrin counterparts. Using new application methods, regiospecifically substituted cyclodextrins can be provided in areas of absorbent articles that would not be possible with their conventional β-cyclodextrin counterparts. Furthermore, regiospecifically substituted cyclodextrins can provide greater efficacy than their conventional β-cyclodextrin counterparts.

[0081] As is known, cyclodextrins are a family of compounds (cyclic oligosaccharides) in which several glucose units are linked together in a ring structure. More specifically, cyclodextrins are formed by five or more α-D-glucopyranoside units linked via glycosidic bonds at the 1- and 4-positions on the glucose ring. Typically, the number of glucose units forming each ring is 6 to 12, and the most common forms are those with 6, 7, or 8 glucose units, also known as α-cyclodextrin, β-cyclodextrin, and γ-cyclodextrin, respectively.

[0082] In all cyclodextrins, each glucose unit has three OH groups attached to carbon atoms at positions 2, 3, and 6. As previously mentioned, the present inventors have surprisingly found that the use of regiospecifically substituted cyclodextrins offers advantages over their β-cyclodextrin and fully substituted counterparts.

[0083] As used herein, the term "regiospecifically substituted cyclodextrin" includes any cyclodextrin in which one or more hydrogen atoms of the OH groups at positions 2 and 6 of a glucose unit are replaced by a substituent -R, thereby forming an -OR group. Similarly, as used herein, the term "fully substituted cyclodextrin" includes any cyclodextrin in which each of the OH groups at positions 2, 3, and 6 is replaced by an OR group. The average number of -R substituents for each glucose unit in a given sample represents the "degree of substitution" (DS), which is a number ranging from 0 to 3, with 0 corresponding to no substitution (all OH groups at positions 2, 3, and 6 are present) and 3 corresponding to complete substitution (all OH groups at positions 2, 3, and 6 are replaced by OR groups). The average is calculated on a molar basis.

[0084] The absorbent article of the present invention comprises a substituted cyclodextrin complex of one or more odor-controlling organic compounds, the substituted cyclodextrin complex comprising a regiospecifically substituted cyclodextrin having a degree of substitution (DS) of -R substituents per cyclodextrin molecule of 0.4 or more, with 20% or more substitution at the 2-position and 20% or more substitution at the 6-position.

[0085] In some embodiments of the present invention, the average degree of substitution may be 0.4 to 2.5, 0.9 to 2.4, 1.2 to 2.2, or 1.6 to 2.1 (specifically, all values ​​within these ranges and any ranges created by these values ​​are listed). In some embodiments of the present invention, the substitution at the 2-position may be 20 to 90%, more preferably 45% to 80%. In some embodiments of the present invention, the substitution at the 6-position may be 20 to 90%, more preferably 45% to 80%. In some embodiments, the present invention may include combinations of the above-mentioned preferred embodiments.

[0086] It is noteworthy that regiospecifically substituted cyclodextrins are synthesized from conventional cyclodextrins. Through this synthesis, a variety of cyclodextrin molecules are produced. For example, some of the cyclodextrin molecules may be completely unsubstituted, i.e., all OH groups at the 2-, 3-, and 6-positions are present. As another example, some of the cyclodextrin molecules may be substituted as desired (i.e., regiospecifically substituted cyclodextrins). And, as another example, some of the cyclodextrins may undergo complete substitution (i.e., all OH groups are replaced by OR groups at the 2-, 3-, and 6-positions). However, as described herein, regiospecifically substituted cyclodextrins having substitution at the 2- and 6-positions offer additional advantages over fully substituted cyclodextrins. Thus, embodiments of the present invention are contemplated in which the degree of substitution at the 3-position is less than the level of substitution at the 2- and / or 6-positions. In some embodiments, the degree of substitution at the 3-position is less than about 50%, less than about 40%, less than about 30%, less than about 20%, or less than about 10% (specifically, all values ​​within these ranges and any ranges created by these values ​​are recited).

[0087] The -R group in the -OR group can be selected from any substituent having a carbon atom at the 1-position (thereby forming an -O-C- bond with the oxygen). Suitable -R substituents can include a carbon atom chain, which can be saturated or unsaturated, straight-chain or branched. For example, suitable -R substituents include saturated and straight-chain C1-6 alkyl, hydroxyalkyl, and mixtures thereof. Particularly suitable -R substituents have a carbon chain of 1 to 6 carbon atoms and are selected from alkyl, hydroxyalkyl, dihydroxyalkyl, carboxy-alkyl, aryl, maltosyl, allyl, benzyl, alkanoyl, and mixtures thereof, where the term "alkyl" encompasses both straight-chain and branched alkyl chains.

[0088] In some embodiments, the -R substituents can include propyl, ethyl, methyl, and hydroxypropyl. Different -R substituents can be present in the same regiospecifically substituted cyclodextrin sample on the same cyclodextrin molecule and even on the same cyclodextrin glucose unit.

[0089] In one particular embodiment, all of the -R substituents may be methyl. In this case, the cyclodextrin is also referred to as a "methylated β-cyclodextrin." For example, a cyclodextrin material particularly suitable for the present invention is a methylated cyclodextrin having a DS of 0.4 or greater, preferably 0.4 to 2.5, more preferably 0.9 to 2, and even more preferably 1.2 to 1.8, in which at least 20%, preferably 20% to 90%, and more preferably 45% to 80% of the -OH groups at positions 2 and 6 are methylated.

[0090] The degree of substitution can be determined by gas chromatography as described below for methyl substituents in β-cyclodextrin.

[0091] Surprisingly, it has been found that the substituted cyclodextrin complexes according to the present invention release odor-controlling organic compounds more rapidly when the absorbent article is contacted with aqueous fluids compared to similar complexes in which the cyclodextrin does not contain a regiospecifically substituted cyclodextrin or in which the substitutions are distributed between the 2-, 3-, and 6-positions.

[0092] Generally, cyclodextrin complexes, including substituted cyclodextrin complexes, can help prevent the evaporation of complexed fragrance compounds. During use, moisture from urine or menstrual fluids contacts the cyclodextrin complex and dissolves the crystalline structure of the cyclodextrin complex, thereby releasing the fragrance material within the cyclodextrin complex. However, problems exist when incorporating cyclodextrin complexes into absorbent hygienic articles. Other components of the absorbent article, such as the absorbent core and / or superabsorbent material, have a strong affinity for bodily fluids, such as menstrual fluids and urine, which contain water. Therefore, when the absorbent article is exposed to bodily fluids, such as menstrual fluids or urine, the cyclodextrin complex may compete with the absorbent core and / or superabsorbent material for the moisture contained in the bodily fluids. The absorbent core and / or superabsorbent material have a strong affinity for water, and when the absorbent core and / or superabsorbent material come into contact with bodily fluids, the absorbent core and / or superabsorbent material effectively "fix" the water from the bodily fluids, thereby reducing the amount of water available to contact the cyclodextrin complexes. As such, the amount of water available to dissolve the cyclodextrin crystal structure and release the fragrance compounds to provide odor control benefits may be limited.

[0093] In conventional cyclodextrin complexes, a larger amount of water may be required to solubilize the cyclodextrin molecules and release the encapsulated fragrance.The same applies to fully substituted cyclodextrins, which are substituted at the 2-, 3-, and 6-positions.However, the present inventors have surprisingly found that by using the position-specifically substituted cyclodextrins described herein, less water may be required to solubilize the position-specifically substituted cyclodextrins.Therefore, more fragrance complex compounds can be released without impairing the absorption capacity or retention capacity of absorbent articles.

[0094] The substituted cyclodextrin may be present in the odor control compositions of the present disclosure in an amount of about 40 percent or greater, or more preferably about 50 percent or greater (specifically, all values ​​within these ranges and any ranges created by these values ​​are recited). For example, the substituted cyclodextrin may be present in the odor control compositions of the present disclosure in an amount of about 40% to about 60% by weight, or more preferably about 50% to about 60% by weight (specifically, all values ​​within this range and any ranges created by this value are recited). Without being bound by theory, it is believed that at concentrations greater than about 60% by weight, the solubility of the substituted cyclodextrin may become an issue.

[0095] Measurement of methyl substituent distribution The methyl substituent distribution in methylated β-cyclodextrin (hereinafter "mBCD") is measured using a gas chromatograph with split / splitless injection and flame ionization detection (a suitable instrument is an Agilent 7890B GC, or equivalent, available from Agilent, Santa Clara, CA). The β-cyclodextrin is hydrolyzed, reduced, and then acetylated for analysis. Further, gas chromatography / mass spectrometry (a suitable unit is a 5777A Mass Selective Detector (MSD), also available from Agilent, or equivalent) can be used to identify the acetylated product and confirm peak identity. Both instruments are calibrated and operated according to the manufacturer's instructions.

[0096] Derivatization reagents, with the exception of borohydride (98%), must be used at 99% purity or greater and may be obtained from Sigma-Aldrich or equivalent. 50 mg of mBCD and 5 mL of 2 M trifluoroacetic acid solution were added to a 50 mL round-bottom flask equipped with a magnetic stir bar. The reaction vessel was fitted with a water-cooled condenser and heated to reflux with stirring for 4 hours. After hydrolysis was complete, the reaction mixture was evaporated to dryness under vacuum. Next, the hydrolysis product, 10 mL of ammonium hydroxide (32% in water), and 101 mg of sodium borohydride (2.67 mmol) were stirred in a 50 mL round-bottom flask at 40 °C for 2 hours. Residual sodium borohydride was quenched by the dropwise addition of glacial acetic acid until the pH of the solution reached a range of 4.5–6. The resulting boric acid was removed by successive additions of methanol (4 × 20 mL) to the reaction mixture, followed by evaporation under vacuum at 40 °C. The reaction product, 10 mL of pyridine, 36 mg of 4-dimethylaminopyridine (0.2947 mmol), and 630 μL of acetic anhydride (630 μL, 6.6794 mmol) were added to a 50 mL round-bottom flask equipped with a magnetic stir bar. The reaction was vigorously stirred at room temperature for 20 hours. The acetylated alditol product was extracted with 10 mL of chloroform using a 60 mL separatory funnel and washed three times with 10 mL of deionized water. The chloroform extract was diluted (1:3) with chloroform and sampled for gas chromatography analysis.

[0097] GC analysis was performed on a 30 m long x 0.250 mm internal diameter column with a 5% phenylarylenemethylpolysiloxane phase with a 1 μm film thickness (a suitable column is the DB5MS available from Agilent, or an equivalent USP G27 phase). The GC inlet was set to 280 °C in split mode (5:1 split, glass wool-packed liner) with a 3 mL septum purge. A column flow rate of 1.5 mL / min of helium was set at a constant flow rate with an oven temperature of 150 °C. The detector was set to 300 °C, and the flow rate was set to the instrument manufacturer's recommended conditions. The GC oven was programmed to start at 150 °C for 1 min, then ramp to 250 °C at 15 °C / min, hold at 250 °C for 4 min, then ramp to 315 °C at 10 °C / min, and hold for 1 min. 1 μL of the chloroform extract was injected for analysis. It will be appreciated that one skilled in the art can slightly modify the chromatographic conditions as needed to achieve the required separation.

[0098] GC-MS analysis was performed under the same chromatographic conditions as for flame ionization detection (FID). The temperatures of the MSD transfer line and detector were set at 280°C and 300°C, respectively. The MSD was configured for electron ionization at -70 eV, scanning from 35 m / z to 400 m / z at a scan rate of 257 ms / scan. The total ion chromatogram was evaluated using the fragmentation data in Table 1 to assign retention orders for the glucitol products. The retention orders were then applied to the GC-FID chromatogram.

[0099] For quantification, each peak measured by GC-FID associated with a glucitol monomer is integrated to obtain the peak area. The areas are then used in Equations 1 and 2 to calculate the mole percent (mol%) of each glucitol monomer and are reported to the nearest 0.1 mol%. Results from the example chromatograms are shown in Table 7.

[0100]

number

[0101]

number

[0102] Furthermore, the mole % of a particular substitution is calculated by adding the individual mole %. For example, the mole % of all glucitols methylated at the 6-position (denoted as X6 in Table 7) is the sum of the mole % of S2,6, S3,6, and S2,3,6.

[0103] The average degree of substitution was calculated according to Equation 3. The mole % for all glucitol monomers sharing the same number of methyl substituents (0, 1, 2, or 3) was summed, multiplied by their respective number of methyl substituents (0, 1, 2, or 3), and divided by 100. Results are reported in increments of 0.1 mole %.

[0104]

number

[0105] Data from gas chromatograms of acetylated D-glucitol derivatives prepared from mBCD using the procedure described above are provided in Table 7. Table 7 shows selected fragments of ionized D-glucitol acetate, and Figure 1 is the FID trace.

[0106] [Table 7]

[0107] Table 8 provides data on the substituent distribution, the average degree of methylation at the O6 and O2 positions, and the average degree of substitution per glucose unit (DS) for mBCD.

[0108] [Table 8]

[0109] The regiospecifically substituted cyclodextrins of the present invention can be prepared by using methods known in the art for selective modification of cyclodextrins. For example, they may be prepared by the method described by Khan et al. (Chem. Rev. 1998, 98, 1977-1996). Alternative synthetic routes for preparing the regiospecifically substituted cyclodextrins of the present invention are known to those skilled in the art and are widely described in the literature. For example, U.S. Patent No. 5,710,268 and the textbooks "Advances in cyclodextrin chemistry" by Werz, Vidal, Guiou, Sollogoub, Matthieu, Wiley-VCH Verlag GmbH ed. 2014 and "Modern Synthetic Methods in Carbohydrate Chemistry: From Monosaccharides to Complex Glycoconjugates", Werz, Daniel B.; Vidal, Sebastian, eds., 2014 Wiley-VHC Verlag GmbH provide further details.

[0110] Once the regiospecifically substituted cyclodextrin is provided, substituted cyclodextrin complexes of odor control organic compounds that are active against malodors can be prepared as known in the art for known cyclodextrin complexes, for example, using the kneading method described in U.S. Pat. Nos. 5,571,782 and 5,543,157, or using the spray drying method described in WO 2008 / 104690(A2).

[0111] Exemplary odor control compositions were made in accordance with the present disclosure, with contents and weight percentages shown in Table 1 below.

[0112] [Table 9]

[0113] Additionally, while weight percentages have been provided above for the components of the odor control compositions, these weight percentages were provided in aqueous form. The weight percentages of the components of the odor control compositions of the present disclosure, excluding water, after the odor control compositions have dried are provided in Table 2.

[0114] [Table 10]

[0115] In dry form, the odor control composition of the present disclosure may comprise a substituted cyclodextrin in a weight percentage of about 80% to about 90%, or more preferably about 85% to about 90% (specifically, all values ​​within these ranges and any ranges created by these values ​​are recited). The fragrance may be present in an amount of about 8% to about 10%, or more preferably about 9% to about 10% (specifically, all values ​​within these ranges and any ranges created by these values ​​are recited). The surfactant may be present in an amount of about 0.3% to about 2.0%, more preferably 0.5% to about 2.0%, or most preferably about 0.8% to about 2.0% (specifically, all values ​​within these ranges and any ranges created by these values ​​are recited). Additionally, the preservative may be present in an amount of 0.5% to 2.0%, more preferably 0.8% to about 2.0%, or most preferably about 1.2% to about 2.0% (specifically, all values ​​within these ranges and any ranges created by these values ​​are recited).

[0116] absorbent articles The odor control composition of the present disclosure may be provided in any suitable location in an absorbent article. For example, an absorbent article of the present disclosure includes a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet. The odor control composition may be provided on the topsheet, on the absorbent core, and / or on the inner surface of the backsheet. When the odor control composition in the absorbent article is wetted by a liquid discharge, the substituted cyclodextrin releases the perfume therein to help mask the odor of the liquid discharge. Therefore, the odor control composition can be placed in a location within the article that is accessible to liquid discharge into the absorbent article.

[0117] With regard to specific components of the absorbent article, the topsheet is preferably compliant, soft-feeling, and non-irritating to the wearer's skin and hair. Furthermore, the topsheet is liquid pervious, permitting liquids (e.g., menses and / or urine) to readily penetrate through its thickness. Suitable topsheets may be manufactured from a wide range of materials, including woven and nonwoven materials (e.g., fibrous nonwoven webs), polymeric materials such as apertured thermoplastic films, apertured plastic films, and hydroformed thermoplastic films, porous foams, reticulated foams, reticulated thermoplastic films, and thermoplastic scrims. Suitable woven and nonwoven materials may be composed of natural fibers (e.g., wood or cotton fibers), synthetic fibers (e.g., polymeric fibers such as polyester, polypropylene, or polyethylene fibers), or a combination of natural and synthetic fibers. When the topsheet comprises a nonwoven web, the web may be manufactured by a number of well-known techniques. For example, the web may be spunbonded, carded, wet-laid, meltblown, hydroentangled, combinations of the above, and the like.

[0118] In some configurations, the topsheet may be a laminate of two or more materials, including, for example, a nonwoven and a film. In such configurations, the nonwoven may form the body-facing surface of the topsheet. Alternatively, the film may form at least a portion of the body-facing surface of the topsheet. Films for use as topsheets are described in U.S. Patent Nos. 4,629,643, 5,460,623, and 6,563,013. Further examples of formed films suitable for use as topsheets or portions thereof are described in U.S. Pat. No. 3,929,135, issued to Thompson on December 30, 1975; U.S. Pat. No. 4,324,246, issued to Mullane et al. on April 13, 1982; U.S. Pat. No. 4,342,314, issued to Radel et al. on August 3, 1982; U.S. Pat. No. 4,463,045, issued to Ahr et al. on July 31, 1984; U.S. Pat. No. 5,006,394, issued to Baird on April 9, 1991; U.S. Pat. No. 4,609,518, issued to Curro et al. on September 2, 1986; and U.S. Pat. No. 4,629,643, issued to Curro et al. on December 16, 1986.

[0119] Non-limiting examples of woven and nonwoven materials suitable for use as a topsheet or portion thereof include fibrous materials made from natural fibers, modified natural fibers, synthetic fibers, or combinations thereof. These fibrous materials can be hydrophilic or hydrophobic, although the topsheet is preferably hydrophobic or rendered hydrophobic. Some suitable nonwoven materials suitable for use as a topsheet are described in U.S. Patent Nos. 5,792,404 and 5,665,452.

[0120] The backsheet can be impervious to liquids (e.g., menses and / or urine) and is preferably made from a thin plastic film, although other flexible materials, such as nonwovens, may also be used. As used herein, the term "flexible" refers to a material that is conformable and easily conforms to the general shape and contours of the human body. The backsheet may prevent articles contacting the absorbent article, such as bed sheets, pants, pajamas, and underwear, from becoming wet due to exudates absorbed and retained in the absorbent core. The backsheet may also be liquid-impervious yet vapor-permeable ("breathable"). The backsheet may comprise a woven or nonwoven material, a polymeric film, such as a thermoplastic film of polyethylene or polypropylene, or a composite material, such as a film-coated nonwoven material.

[0121] The backsheet may include panty fastening means attached to a surface thereof, particularly the surface facing outward from the absorbent article, so that the article will stay in place between the user's crotch and panties when worn. Such panty fastening means may be, for example, a layer of adhesive such as Velcro® or mechanical means, or a combination thereof. If an adhesive is present, a release paper is usually also present to protect the adhesive prior to use.

[0122] The backsheet and topsheet may be positioned adjacent the garment-facing and body-facing surfaces of the absorbent core, respectively. The absorbent core can be joined to the topsheet, the backsheet, or both by any known attachment means, such as methods well known in the art. Embodiments of the invention are contemplated in which portions of the entire absorbent core are not attached to either the topsheet, the backsheet, or both.

[0123] The absorbent core can be formed from any material known to those skilled in the art. Examples of such materials include multi-ply creped cellulose wadding, fluffed cellulose fibers, wood pulp fibers, also known as airfelt, textile fibers, fiber blends, fiber lumps or batts, aeolian webs of fibers, webs of polymeric fibers, and blends of polymeric fibers. Other suitable absorbent core materials include absorbent foams such as polyurethane foams or high internal phase emulsion ("HIPE") foams. Suitable HIPE foams are disclosed in U.S. Patent Nos. 5,550,167, 5,387,207, 5,352,711, and 5,331,015. Other suitable materials for use in the absorbent core include open-cell foams or fragments thereof. The use of foam in absorbent cores is described in further detail in U.S. Patent Nos. 6,410,820, 6,107,356, 6,204,298, 6,207,724, 6,444,716, 8,211,078, and 8,702,668.

[0124] In some embodiments, the absorbent core structure may include a heterogeneous mass layer, or may be a composite of layers as described in U.S. Patent Application No. 14 / 715,984, filed May 19, 2015, U.S. Patent Application No. 14 / 750,399, filed June 25, 2015, U.S. Patent Application No. 14 / 751,969, filed June 26, 2015, U.S. Patent Application No. 15 / 078,132, filed March 23, 2016, U.S. Patent Application No. 14 / 750,596 ... March 25, 2016, U.S. Patent Application No. U.S. Patent Application No. 15 / 084,902 filed on November 30, 2016, U.S. Patent Application No. 15 / 343,989 filed on November 4, 2016, U.S. Patent Application No. 15 / 344,273 filed on November 4, 2016, U.S. Patent Application No. 15 / 344,294 filed on November 4, 2016, U.S. Patent Application No. 14 / 704,110 filed on May 5, 2015, U.S. Patent Application No. 15 / 194,894 filed on June 28, 2016, U.S. Patent Application No. 15 / 194,894 filed on November 4, 2016 No. 15 / 344,050, U.S. Patent Application No. 15 / 344,117 filed November 4, 2016, U.S. Patent Application No. 15 / 344,177 filed November 4, 2016, U.S. Patent Application No. 15 / 344,198 filed November 4, 2016, U.S. Patent Application No. 15 / 344,221 filed November 4, 2016, U.S. Patent Application No. 15 / 344,239 filed November 4, 2016, U.S. Patent Application No. 15 / 344,250 filed November 4, 2016 No. 5, U.S. Patent Application No. 15 / 464,733, filed November 4, 2016, U.S. Provisional Patent Application No. 62 / 437,208, filed December 21, 2016, U.S. Provisional Patent Application No. 62 / 437,225, filed December 21, 2016, U.S. Provisional Patent Application No. 62 / 437,241, filed December 21, 2016, or U.S. Provisional Patent Application No. 62 / 437,259, filed December 21, 2016, may be utilized. The heterogeneous mass layer has a depth, a width, and a height.

[0125] In some configurations, a combination of absorbent core materials may be utilized. For example, configurations are contemplated in which a first layer of the absorbent core comprises a foam material or fragments thereof, as described above, and a second layer of the absorbent core comprises an airlaid material. Such combinations are described in U.S. Patent Application Publication No. 2014 / 0336606 and U.S. Patent No. 9,649,228.

[0126] In some absorbent articles, the absorbent core may be relatively thin, having a thickness of less than about 5 mm, or less than about 3 mm, or less than about 1 mm. Thickness can be determined by any means known in the art, such as measuring the thickness at the midpoint along the longitudinal centerline of the pad while under a uniform pressure of 1.72 kPa.

[0127] The absorbent core can comprise a superabsorbent material, such as an absorbent gelling material (AGM) comprising AGM fibers, as is well known in the art. Thus, the absorbent core can comprise a layer comprising the superabsorbent material.

[0128] The absorbent article may include other additional components, such as a secondary topsheet or acquisition layer, between the topsheet and the absorbent core. The secondary topsheet or acquisition layer may include a tissue layer or a nonwoven, such as a carded resin-bonded nonwoven, an embossed carded resin-bonded nonwoven, a high-bulk carded resin-bonded nonwoven, a carded air-through bonded nonwoven, a carded heat-sealed nonwoven, or a spunbonded nonwoven. Various fibers can be used in the secondary topsheet or acquisition layer, including natural fibers such as wood pulp, cotton, and wool, as well as biodegradable fibers such as polylactic acid fibers, and synthetic fibers such as polyolefins (e.g., polyethylene and polypropylene), polyesters, polyamides, synthetic cellulose derivatives (e.g., RAYON®, Lyocell), cellulose acetate, bicomponent fibers, and blends thereof. The basis weight of the secondary topsheet or acquisition layer may vary depending on the desired application. In some embodiments, the secondary topsheet or acquisition layer may include a superabsorbent polymer, such as AGM, deposited thereon. In such configurations, the secondary topsheet or acquisition layer may comprise a first AGM and the absorbent core may comprise a second AGM. In some configurations, the first AGM may be different from the second AGM.

[0129] The absorbent article may also include additional components such as side cuffs, which are typically found in diapers, or side wings or side flaps, which are typically found in sanitary napkins.

[0130] Absorbent catamenial tampons are absorbent articles for use within the vagina, usually made from a pledget containing absorbent fibers compressed into a cylindrical shape. Tampons can be "digital tampons," which are freestanding and can be inserted with a finger, or "applicator tampons," i.e., tampons introduced using an applicator. Tampons may also include a withdrawal string to facilitate removal from the vagina.

[0131] The absorbent sanitary articles herein are often commercialized in packages containing multiple units, often in plastic film or cardboard boxes. The single units contained in the commercial package may or may not be individually wrapped.

[0132] In some configurations, the absorbent articles of the present disclosure may include additional layers disposed between the topsheet and the absorbent core and / or between the absorbent core and the backsheet. Some examples include a secondary topsheet, acquisition layer, and / or distribution layer, which may be exposed between the topsheet and the absorbent core. Other examples include a distribution layer or a liquid-impermeable layer disposed between the absorbent core and the backsheet.

[0133] In some embodiments, the substituted cyclodextrin complex, e.g., mBCD, may be delivered within a target zone of an absorbent article. As shown in Figure 2, the target zone 330 of the absorbent article 300 represents the area of ​​the absorbent article where fluid release is expected. The absorbent article 300 is shown having an overall longitudinal length generally parallel to the Y axis and an overall lateral width generally parallel to the X axis. The absorbent article 300 further includes a thickness in the Z direction (not shown), which is perpendicular to the XY plane formed by the X and Y axes.

[0134] As shown, the target zone 330 may be disposed between two outer zones 335. In some forms, the target zone 330 may comprise approximately 60% of the total longitudinal length (along the Y-axis) of the absorbent article 300, with each of the outer zones comprising up to approximately 30 percent of the total length of the absorbent article 300. In some forms, the target zone 330 may comprise approximately 50% of the total length of the absorbent article, with the outer zone 335 comprising up to approximately 40% of the total length of the absorbent article. In some forms, the target zone 330 may extend from greater than about 20% to less than about 80%, greater than about 30% to less than about 70%, or greater than about 40% to less than about 60% of the total length of the absorbent article 300 (specifically, all values ​​within these ranges and any ranges created by these values ​​are recited).

[0135] Configurations are contemplated in which the target zone 330 extends along only a portion of the overall lateral width (along the X-axis) of the absorbent article 300. For example, in some configurations, the target zone 330 may extend across less than about 90% of the overall width of the absorbent article 300. As another example, the target zone 330 may extend across less than about 75% of the overall width of the absorbent article 300. In yet other configurations, the target zone 330 may extend across less than about 50% of the overall width of the absorbent article 300. As yet other examples, the target zone 330 may extend across more than about 10% to less than about 90%, more than about 20% to less than about 80%, or more than about 30% to less than about 70% of the overall width (specifically, all values ​​within these ranges and any ranges created by these values ​​are recited). In such configurations, the region of the article outside the target zone 330 may be free of the substituted cyclodextrin complex. Or, in other embodiments, target zone 330 may contain more substituted cyclodextrin complexes than either of outer zones 335 .

[0136] In the case of catamenial tampons, the substituted cyclodextrin complex can be present on or in any component of the tampon, including the absorbent compressed pledget that forms the tampon body, the overwrap, and the withdrawal cord. For example, it can be contained in the tampon body, on the surface of the tampon, or on any surface of the overwrap, if present. If a secondary mass of absorbent material is present along an extension cord proximal to the withdrawal end of the tampon, the substituted cyclodextrin complex may be contained in this secondary mass.

[0137] In all cases, the substituted cyclodextrin complexes of the present invention can be applied in powder form to one of the layers constituting the absorbent article, or can be incorporated into a liquid or semi-solid carrier and applied as a lotion. In this case, the substituted cyclodextrin complex is dispersed in the carrier to form a dispersion, which can then be applied to the absorbent article. The carrier can be selected from the group consisting of, for example, polysiloxane oil, mineral oil, petrolatum, polyethylene glycol, glycerin, etc., and mixtures thereof. The carrier is preferably a polysiloxane oil, such as a silicone glycol copolymer (commercially available from Dow Corning as Dow Corning 190 Fluid).

[0138] As mentioned above, the odor control composition of the present disclosure can be applied to any suitable location on a disposable absorbent article.However, it is believed that a process involving spraying an odor control complex onto one or more layers of a disposable absorbent article may cause contamination when the odor control complex is applied to several layers.For example, because a topsheet is designed for rapid fluid acquisition, it may be permeable to such an extent that when spraying the odor control composition onto the topsheet, a portion of the odor control composition passes through the topsheet and reaches the manufacturing equipment, thereby causing contamination in the manufacturing line.Similarly, a secondary topsheet may be designed to be permeable to such an extent that a portion of the sprayed odor control composition can blow through the secondary topsheet.

[0139] In contrast, the absorbent core is often the densest layer of a disposable absorbent article. Therefore, when the odor control composition is sprayed onto the absorbent core, it is much less likely that a portion of the odor control composition will blow through the layer. Therefore, in some embodiments, the odor control composition of the present disclosure may be provided on the absorbent core.

[0140] It should be noted that additional optional layers may be provided between the topsheet and the absorbent core and / or between the backsheet and the absorbent core, and thus the aqueous odor control composition of the present disclosure may be applied to one or more layers comprising a disposable absorbent article.

[0141] Other mechanisms for applying the odor control composition are contemplated. In addition, the odor control composition of the present disclosure may be applied to the AGM in the absorbent core, as disclosed in U.S. Patent Application Publication No. 2018 / 033515. In addition, if the absorbent article manufacturer obtains a web of material from a supplier, the provision of the odor control composition may be provided by the material supplier. For example, the absorbent core supplier may apply the odor control composition to the absorbent core raw material, which may then be converted by the absorbent article manufacturer. Independently or in conjunction therewith, a topsheet supplier, a secondary topsheet supplier, or other raw material supplier may apply the odor control composition of the present disclosure to the raw material, which is then converted into an absorbent article.

[0142] The odor control compositions of the present disclosure are aqueous-based during application to disposable absorbent articles and / or the layers that make up the disposable absorbent articles. Manufacturers of disposable absorbent articles may obtain aqueous odor control compositions from suppliers, or they may manufacture the odor control compositions themselves.

[0143] Extraction of mBCD from absorbent articles mBCD can be collected from whole articles or components by Soxhlet extraction with water followed by removal of the solvent (water) using a rotary evaporator. Enough articles should be extracted to collect 50 mg of mBCD for further analysis of methyl substitution.

[0144] Dimensions and values ​​disclosed herein should not be understood as being strictly limited to the exact numerical values ​​recited. Instead, unless otherwise indicated, each such dimension is intended to mean both the recited value and a functionally equivalent range surrounding that value. For example, a dimension disclosed as "40 mm" is intended to mean "about 40 mm."

[0145] All documents cited herein, including cross-referenced documents or related patents or applications, are incorporated herein by reference in their entirety unless expressly excluded or otherwise limited. The citation of any document shall not be deemed to be prior art to any invention disclosed or claimed herein, or to teach, suggest, or disclose any such invention, either alone or in combination with any other reference(s). Furthermore, to the extent that any meaning or definition of a term in this document conflicts with any meaning or definition of the same term in a document incorporated by reference, the meaning or definition assigned to that term in this document shall govern.

[0146] While particular embodiments of the present invention have been illustrated and described, it would be obvious to those skilled in the art that various other changes and modifications can be made without departing from the spirit and scope of the invention. It is therefore intended to cover in the appended claims all such changes and modifications that are within the scope of this invention.

Claims

1. 1. A disposable absorbent article comprising a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet, wherein the disposable absorbent article comprises an odor control composition, the odor control composition comprising a preservative, a cyclodextrin-compatible surfactant, a substituted cyclodextrin, and a fragrance; the odor control composition comprising, based on the total weight of the odor control composition, 0.5% to 1.0% by weight of a preservative, and 0.01% to 2.0% by weight of a surfactant; A disposable absorbent article, wherein the cyclodextrin is a substituted cyclodextrin having a degree of substitution (DS) of 0.4 to 2.5 -R substituents per glucose unit of the cyclodextrin, in which H atoms of OH groups at the 2-, 3-, and 6-positions of the substituted cyclodextrin are partially or completely replaced by the substituent -R, the substitution at the 2-position is 20% or more, the substitution at the 6-position is 20% or more, and the substitution at the 3-position is less than the degree of substitution at the 2- and / or 6-positions.

2. The preservative has the following structure I: HO-CH ２ -CH ２ -R(I) 10. The disposable absorbent article of claim 1, comprising a compound represented by the formula: wherein R is a substituted or unsubstituted phenyl group, or a substituted or unsubstituted phenoxy group.

3. 3. The disposable absorbent article of claim 1 or 2, wherein the substitution at the 3-position is less than 50%.

4. 3. The disposable absorbent article of claim 1 or 2, wherein the substitution at the 3-position is less than 40%.

5. 3. The disposable absorbent article of claim 1 or 2, wherein the substitution at the 3-position is less than 30%.

6. The absorbent article according to any one of claims 1 to 5, wherein said substituted cyclodextrin has a degree of substitution of from 0.9 to 2.

4.

7. The disposable absorbent article according to any one of claims 1 to 6, wherein said substituted cyclodextrin has a degree of substitution of from 1.2 to 2.

2.

8. The disposable absorbent article according to any one of claims 1 to 7, wherein said substituted cyclodextrin has a degree of substitution of from 1.6 to 2.

1.

9. The disposable absorbent article of any one of claims 1 to 8, wherein the substitution at the 2-position is between 20% and 90%.

10. The disposable absorbent article of any one of claims 1 to 9, wherein the substitution at the 2-position is between 45% and 80%.

11. The disposable absorbent article of any one of claims 1 to 10, wherein the substitution at the 6-position is between 20% and 90%.

12. The absorbent article of any one of claims 1 to 11, wherein the substitution at the 6-position is between 40% and 80%.

13. The disposable absorbent article according to any one of claims 1 to 12, wherein said -R substituents are selected from linear or branched C1 to C5 saturated chains.

14. The disposable absorbent article of any one of claims 1 to 12, wherein said -R substituents are selected from methyl and hydroxymethyl.

15. The disposable absorbent article of any one of claims 1 to 14, wherein the odor control composition is provided on the absorbent core.

16. The disposable absorbent article of any one of claims 1 to 15, wherein said perfume comprises a carrier, said carrier comprising isopropyl myristate.

17. The disposable absorbent article of any one of claims 1 to 16, wherein said perfume comprises a carrier, said carrier consisting of isopropyl myristate.

18. The cyclodextrin-compatible surfactant has the general formula: (CH ３ , ３ SiO-[Si(CH ３ , ２ O]a-[Si(CH) ３ )(R １ )O]bSi(CH ３ , ３ wherein a+b is from 1 to 50; and R １ are the same or different and are methyl and a group of the general formula: -(CH ２ ) ｎ O(C ２ H ４ O) ｃ (C ３ H ６ O) ｄ R ２ and at least one R １ is a poly(ethylene oxide / propylene oxide) copolymer group, n is 3 or 4, the sum of c for all polyalkyleneoxy side groups has a value of 1 to 100, d is 0 to 14, and c+d has a value of 9 to 100; and each R ２ The disposable absorbent article of any one of claims 1 to 17, wherein are the same or different and are selected from the group consisting of hydrogen, alkyl having 1 to 4 carbon atoms, and acetyl groups.

19. The surfactant in the odor control composition has the general formula: 【Chemistry 1】 The disposable absorbent article according to any one of claims 1 to 17, wherein the anionic surfactant has the formula: [wherein R is an alkyl group].

20. 18. The disposable absorbent article of any one of claims 1 to 17, wherein the surfactant in the odor control composition is a block copolymer of poly(ethylene oxide) and / or poly(propylene oxide) with hydrophilic poly(ethylene oxide) moieties in terminal positions.

21. The disposable absorbent article of any one of claims 1 to 17, wherein the surfactant of the odor control composition is a polyalkylene oxide polysiloxane.

22. The disposable absorbent article of any one of claims 1 to 21, wherein the perfume is present in an amount of 8% to 10% by weight based on the total weight of the odor control composition.

23. The disposable absorbent article of any one of claims 1 to 22, wherein the substituted cyclodextrin is present in an amount of 80% to 90% by weight based on the total weight of the odor control composition.

24. 1. A method for making a disposable absorbent article having an odor control composition, comprising: obtaining a topsheet material; Obtaining a backsheet material; Obtaining an absorbent core material; disposing the absorbent core material between the topsheet material and the backsheet material; obtaining an aqueous odor control composition comprising a substituted cyclodextrin, a preservative, a cyclodextrin-compatible surfactant, and a fragrance; applying or causing the aqueous odor control composition to be applied to at least one of the topsheet, the backsheet, or the absorbent core; the odor control composition comprising, based on the total weight of the odor control composition, 0.5% to 1.0% by weight of a preservative, and 0.01% to 2.0% by weight of a surfactant; the cyclodextrin is a substituted cyclodextrin having a degree of substitution (DS) of 0.4 to 2.5 -R substituents per glucose unit of the cyclodextrin, in which H atoms of OH groups at positions 2, 3, and 6 of the substituted cyclodextrin are partially or completely replaced by substituents -R, the substitution at position 2 is 20% or more, the substitution at position 6 is 20% or more, and the substitution at position 3 is less than the degree of substitution at positions 2 and / or 6; method.

25. The preservative has the following structure I: HO-CH ２ -CH ２ -R (I) 25. The method of claim 24, comprising a compound represented by the formula: wherein R is a substituted or unsubstituted phenyl group, or a substituted or unsubstituted phenoxy group.

26. 25. The method of claim 24, wherein the substitution at position 3 is less than 50%.

27. 25. The method of claim 24, wherein the substitution at position 3 is less than 40%.

28. 25. The method of claim 24, wherein the substitution at position 3 is less than 30%.

29. 29. The method according to any one of claims 24 to 28, wherein the substituted cyclodextrin has a degree of substitution of from 0.9 to 2.

4.

30. 30. The method of any one of claims 24 to 29, wherein the substituted cyclodextrin has a degree of substitution of 1.2 to 2.

2.

31. 31. The method of any one of claims 24 to 30, wherein the substituted cyclodextrin has a degree of substitution of 1.6 to 2.

1.

32. 32. The method of any one of claims 24 to 31, wherein the substitution at position 2 is between 20% and 90%.

33. 33. The method of any one of claims 24 to 32, wherein the substitution at position 2 is between 45% and 80%.

34. 34. The method of any one of claims 24 to 33, wherein the substitution at position 6 is between 20% and 90%.

35. 35. The method of any one of claims 24 to 34, wherein the substitution at position 6 is between 40% and 80%.

36. 36. The method of any one of claims 24 to 35, wherein the -R substituent is selected from a straight or branched C1 to C5 saturated chain.

37. The disposable absorbent article of any one of claims 24 to 35, wherein said -R substituents are selected from methyl and hydroxymethyl.

38. The method of any one of claims 24 to 37, wherein the odor control composition is provided on the absorbent core.

39. 39. The method of any one of claims 24 to 38, wherein the flavoring agent comprises a carrier, and the carrier comprises isopropyl myristate.

40. 39. The method of any one of claims 24 to 38, wherein the perfume comprises a carrier, and the carrier comprises isopropyl myristate.

41. The cyclodextrin-compatible surfactant has the general formula: (CH ３ , ３ SiO-[Si(CH ３ , ２ O]a-[Si(CH) ３ )(R １ )O]bSi(CH ３ , ３ wherein a+b is from 1 to 50; and R １ may be the same or different, methyl and the general formula: -(CH ２ ) ｎ O(C ２ H ４ O) ｃ (C ３ H ６ O) ｄ R ２ and at least one R １ is a poly(ethylene oxide / propylene oxide) copolymer group, n is 3 or 4, the sum of c for all polyalkyleneoxy side groups has a value of 1 to 100, d is 0 to 14, c+d has a value of 9 to 100, and each R ２ The method of any one of claims 24 to 40, wherein are the same or different and are selected from the group consisting of hydrogen, alkyl having 1 to 4 carbon atoms, and an acetyl group.

42. The surfactant in the odor control composition has the general formula: 【Chemistry 2】 The method according to any one of claims 24 to 40, wherein the anionic surfactant has the formula: [wherein R is an alkyl group].

43. 41. The method of any one of claims 24 to 40, wherein the surfactant in the odor control composition is a block copolymer of poly(ethylene oxide) and / or poly(propylene oxide) in which hydrophilic poly(ethylene oxide) moieties are in terminal positions.

44. The method of any one of claims 24 to 40, wherein the surfactant of the odor control composition is a polyalkylene oxide polysiloxane.

45. 45. The method of any one of claims 24 to 44, wherein the perfume is present in an amount of 8% to 10% by weight based on the total weight of the odor control composition.

46. 46. ​​The method of any one of claims 24 to 45, wherein the substituted cyclodextrin is present in an amount of 80% to 90% by weight, based on the total weight of the odor control composition.

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