Agricultural components

Abstract

The present disclosure relates to agricultural compositions. In particular, the present disclosure relates to agricultural carrier compositions. More particularly, the present disclosure relates to agricultural carrier compositions that may be loaded with at least one anti-pathogen agent and / or at least one biocontrol agent and / or fertilizer agent and / or biostimulant agent and / or elicitor agent and / or plant growth regulator and / or insect repellent agent. The present disclosure extends to methods of producing the foregoing. The agricultural compositions include (C2-C 26 ) Alkyl lactate and / or its derivatives, (C2-C 22 ) alcohol, a wetting agent; and a nonionic and / or anionic surfactant. The agricultural composition may further comprise a binder to provide an agricultural carrier composition. The agricultural carrier composition may be further loaded with at least one anti-pathogen agent and / or at least one biocontrol agent and / or fertilizer agent and / or biostimulant agent and / or elicitor agent and / or plant growth regulator and / or insect repellent.

Description

[Technical Field]

[0001] Field of the Disclosure The present disclosure relates to agricultural compositions. In particular, the present disclosure relates to agricultural carrier compositions. Even more particularly, the present disclosure relates to agricultural carrier compositions that can be loaded with at least one anti-pathogen agent and / or at least one biocontrol agent and / or fertilizer agent and / or biostimulant agent and / or elicitor agent and / or plant growth regulator and / or insect repellent. The present disclosure extends to methods of making the foregoing. [Background technology]

[0002] background Nematoda are an extremely diverse phylum of animals, ubiquitous in most ecosystems worldwide. In agriculture and horticulture, nematodes can be either beneficial or harmful to plant health, depending on the species. Beneficial nematodes can be predatory, killing pests that negatively affect plant health. Harmful nematodes can directly attack parts of the plant anatomy and, additionally and / or alternatively, can act as vectors to spread plant diseases.

[0003] Harmful nematodes can cause extensive crop damage and are known to be difficult to control and / or eradicate. Harmful nematodes can also be parasitic. Plant-parasitic nematodes are known to contain hollow stylets or spines that are used to puncture plant cells and access food sources. These plant-parasitic nematodes have been noted to secrete metabolites and / or proteins into plant hosts, induce cellular differentiation in those hosts, and provide feeding structures that promote the growth and reproduction of the nematodes, leading to plant invasion and parasitism. Nematodes are known to feed on plant roots, stems, leaves, flowers, and / or seeds. Summary of the Invention [Problem to be solved by the invention]

[0004] With traditional chemical nematicides increasingly being withdrawn from the market due to concerns about environmental and / or ecotoxicological impacts, transgenic approaches are being utilized to deliver defined, specific proteins capable of acting as nematicides and / or nematicidal compositions to crops of transgenic plants. Transgenic approaches are expensive and often not readily available to farmers in developing countries due to their prohibitive cost.

[0005] A wide range of other protocols for controlling and / or killing harmful nematodes are known, including traditional chemical, phytochemical, and / or biocontrol approaches, where biocontrol is to be understood as the use of living organisms to suppress and / or reduce and / or inhibit and / or destroy the population of a particular pest. Single-layer approaches can often have limited success, while multi-layer approaches can result in undesirable side effects.

[0006] For example, in a multi-layered approach, the application of traditional synthetic chemical compounds (or phytosanitary chemical compounds) to plants (or soil) along with biocontrol agents can very well result in the biocontrol agent destroying or harming the synthetic or phytosanitary chemical.

[0007] Organic acids, as well as bacteria and fungi, are known to exhibit nematicidal and / or nematicidal activity. However, it is also known that organic acids can be antibacterial and antifungal. As a result, the selection of active agents in a multi-layer approach is crucial.

[0008] Each component of the multi-layered approach may have a different target and / or mode of action, so that when used together in a treatment program, the overall effect is effective nematode control and / or destruction. In some cases, synergistic effects may occur, but this is not reasonably possible to predict due to the diverse biochemical pathways involved at different target locations and the various modes of action involved. The unpredictability of any success with a multi-layered approach is very high.

[0009] A multi-layer approach can also be used to address resistance, as it is known that nematodes can develop resistance to traditional chemical nematicides.

[0010] Careful selection of the individual components of a multi-layer approach is important to avoid situations where such individual components interfere with or destroy each other. Furthermore, in multi-layer approaches that include multiple active agents for application to plants (or the soil around such plants) in a treatment program, the timing of application is also important to avoid individual components interfering with each other or interfering with the mode of action of the other.

[0011] Typically, multi-layered approach in treatment program may involve applying different components of active agent at different times.This is disadvantageous for farmers because it requires multiple applications, which causes soil compaction caused by agricultural equipment, consumes extra time, and requires extra labor.In addition, it requires high technical understanding of how each component interacts with each other and may interfere with each other, which is disadvantageous in areas with low literacy rate or poor education.

[0012] Simultaneous application of the different components is desirable since separate application of the individual components in the multi-layer approach is disadvantageous.

[0013] When considering the simultaneous application of different components of a multi-layered approach, the optional carrier composition is very important. The chemical composition of such a carrier should not negatively interact with each individual component, yet still ensure the protection of each individual component until it is delivered to its desired target location in the plant (or soil) where its specific mode of action can promote nematode control (and / or destruction). The development of such a carrier composition requires consideration of not only the physicochemical properties of the different components, but also the biochemical and physiological pathways associated with the biocontrol agent, the desired target, and the mode of action. A similar multi-layered approach is also desirable in treatment protocols for controlling and / or destroying other plant pathogens and / or plant pests, including insects, larvae, worms, arachnids, bacteria, fungi, viruses, etc.

[0014] Furthermore, when using a carrier composition, shelf life considerations are important for the simultaneous application of different components of a multi-layer approach. The carrier composition must be stable and have a stable shelf life when combined with a biocontrol agent (chemical or biochemical compound, metabolite, dormant or live biocontrol agent) by itself. The individual components should not negatively interact with each other or with the carrier composition in a way that could shorten the shelf life. The chemical interactions between all individual components must result in a stable composition. It is extremely difficult to predict shelf life based on individual chemical and / or biochemical and / or microbiological factors.

[0015] There is a need in agrochemistry to provide more effective agricultural compositions, particularly those that address pests including nematodes, insects, fungi, and the like, with a multi-layer approach.

[0016] There is also a need to increase the performance of plant protection products and / or reduce the development of resistance thereto by plant pathogens.

[0017] Additionally, there continues to be a need to promote increased agricultural yields and / or improve plant health of agricultural crops.

[0018] The disclosure set forth herein below seeks to ameliorate at least one of the problems set forth above and / or known in the prior art. [Means for solving the problem]

[0019] overview Generally, according to a first aspect of the present disclosure, (C2~C 26 ) alkyl lactate and / or its derivatives; (C2~C 22 )alcohol; Wetting agents; and Nonionic and / or anionic surfactants An agricultural composition is provided, comprising:

[0020] (C2~C 26 ) Alkyl lactate is (C 10 ~C 22 ) alkyl lactate and / or its derivatives.

[0021] (C2~C 26 ) The alkyl lactate and / or derivatives thereof can be at least one selected from the group including, but not limited to, ethyl lactate, propyl lactate, butyl lactate, pentyl lactate, hexyl lactate, heptyl lactate, octyl lactate, nonyl lactate, decyl lactate, undecyl lactate, dodecyl lactate, tridecyl lactate, tetradecyl lactate, pentadecyl lactate, hexadecyl lactate, heptadecyl lactate, octadecyl lactate, nonadecyl lactate, eicosyl lactate, heneicosyl lactate, and docosyl lactate, and / or derivatives of the foregoing.

[0022] Alkyl lactate is (C 10 ~C 22 ) alkyl lactate or any combination and / or derivative of the foregoing and combinations thereof. Preferably, (C 10 ~C22 ) The alkyl lactate and / or its derivatives may be at least one selected from the group including, but not limited to, lauryl lactate (dodecyl lactate), myristyl lactate (tetradecyl lactate), cetyl lactate (hexadecyl lactate), and lactyl lauryl lactate.

[0023] (C2~C 26 ) Alkyl lactate and / or its derivatives are (C2-C 26 ) alkyl lactyl lactate and / or its derivatives.

[0024] (C2~C 26 ) The alkyl lactyl lactate and / or its derivatives may be at least one selected from the group including, but not limited to, ethyl lactyl lactate, propyl lactyl lactate, butyl lactate, pentyl lactyl lactate, hexyl lactyl lactate, heptyl lactate, octyl lactyl lactate, nonyl lactyl lactate, decyl lactate, undecyl lactate, dodecyl lactate, tridecyl lactate, tetradecyl lactate, pentadecyl lactate, hexadecyl lactyl lactate, heptadecyl lactate, octadecyl lactate, nonadecyl lactate, eicosyl lactate and / or derivatives thereof.

[0025] (C2~C 26 ) Lactyl alkyl lactate and / or its derivatives are (C 10 ~C 22 ) alkyl lactylate and / or its derivatives. Preferably, (C 10 ~C 22 ) The lactyl alkyl lactylate can be lauryl lactylate.

[0026] (C2~C 22) The alcohols may include monoalcohols, diols, triols, tetraols, pentaols, hexaols, alkyl alcohols, alkenols, alkynols, primary, secondary, tertiary, aromatic, cyclic, alicyclic, unbranched, branched, saturated, and unsaturated alcohols, and / or any combination and / or derivative of the foregoing.

[0027] (C2~C 22 ) Alcohols include ethanol, propanol, propan-2-ol, butanol, butan-2-ol, pentanol, pentan-2-ol, pentan-3-ol, hexanol, hexane-2-ol, hexane-3-ol, heptanol, heptan-2-ol, heptan-3-ol, heptan-4-ol, octanol, octan-2-ol, Octan-3-ol, Octan-4-ol, 2-ethylhexanol, Nonanol, Nonan-2-ol, Nonan-3-ol, Nonan-4-ol, Nonan-5-ol, Decanol, Decan-2-ol, Decan-3-ol, Decan-4-ol, Decan-5-ol, Undecanol, Undecan-2-ol, Undecan-3-ol, Undecan-4-ol, Undecan-5-ol, Undecan-6-ol, Dodecanol, Dodecan-2-ol, Dodecan-3-ol, Dodecan-4-ol, Dodecan-5-ol, Dodecan-6-ol, Tridecanol nol, tridecan-2-ol, tridecan-3-ol, tridecan-4-ol, tridecan-5-ol, tridecan-6-ol, tridecan-7-ol, tetradecanol, tetradecan-2-ol, tetradecan-3-ol, tetradecan-4-ol, tetradecan-5-ol, tetradecan-6-ol, tetradecan-7-ol, pentadecanol, pentadecane-2-ol, pentadecane-3-ol, pentadecane-4-ol, pentadecane-5-ol, pentadecane-6-ol, pentadecane-7-ol, Pentadecane-8-ol, hexadecanol, hexadecan-2-ol, hexadecan-3-ol, hexadecan-4-ol, hexadecan-5-ol, hexadecan-6-ol, hexadecan-7-ol, hexadecan-8-ol, heptadecanol, heptadecan-2-ol, heptadecan-3-ol, heptadecan-4-ol, heptadecan-5-ol, heptadecan-6-ol, heptadecan-7-ol, heptadecan-8-ol, heptadecan-9-ol, octadecanol, octadecan-2-ol, octadecan- tadecan-3-ol, octadecan-4-ol, octadecan-5-ol, octadecan-6-ol, octadecan-7-ol, octadecan-8-ol, octadecan-9-ol, nonadecanol, nonadecan-2-ol, nonadecan-3-ol, nonadecan-4-ol, nonadecan-5-ol, nonadecan-6-ol, nonadecan-7-ol, nonadecan-8-ol, nonadecan-9-ol, nonadecan-10-ol, eicosanol, eicosan-2-ol, eicosan-3-ol, eicosan-4-ol,Eicosan-5-ol, eicosan-6-ol, eicosan-7-ol, eicosan-8-ol, eicosan-9-ol, eicosan-10-ol, heneicosanol, heneicosan-2-ol, heneicosan-3-ol, heneicosan-4-ol, heneicosan-5-ol, heneicosan-6-ol, heneicosan-7-ol, heneicosan-8-ol, heneicosan-9-ol, heneicosan-10 The hydroxybenzoate may be at least one selected from the group including, but not limited to, heneicosan-11-ol, docosanol, docosan-2-ol, docosan-3-ol, docosan-4-ol, docosan-5-ol, docosan-6-ol, docosan-7-ol, docosan-8-ol, docosan-9-ol, docosan-10-ol and docosan-11-ol, and / or any combination and / or derivative of the foregoing.

[0028] The humectant may be glycerin, glycerol or its alkyl ether, (C2-C 30 ) Alkene glycol, propylene glycol, polypropylene glycol or its alkyl ether, sorbitol, mannitol, dulcitol and / or polyol, alkyl glycoside, linear (C4-C 18 ) Alkyl (poly)glycosides, branched chain (C4-C 18 ) Alkyl (poly)glycosides, linear (C4-C 18 ) Alkyl (poly)glucosides, branched chain (C4-C 18 ) alkyl (poly)glucosides, aryl glycosides, and / or any combinations and / or derivatives of the foregoing.

[0029] Nonionics are natural and / or synthetic (C8-C 22 ) alkoxylated fatty alcohols, (C8-C 22 ) Ethoxylated fatty alcohols, (C8-C 22 ) Propoxylated fatty alcohols, (C8-C 22) Ethoxylated and propoxylated fatty alcohols, (C6-C 22 ) Alkoxylated fatty acids, (C6-C 22 ) Ethoxylated fatty acids, (C6-C 22 ) Propoxylated fatty acids, EO-PO(C6-C 22 ) Ethoxylated and propoxylated fatty acids, linear (C4-C 10 ) Alkyl (poly)glycosides, branched chain (C4-C 10 ) alkyl (poly)glycosides; and at least one selected from the group including, but not limited to, alkoxylated sorbitan fatty acid esters, alkoxylated sorbitol fatty acid esters, ethoxylated sorbitan fatty acid esters, ethoxylated sorbitol fatty acid esters, polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monolaurate, polyoxyethylene glycol sorbitan monolaurate, polyoxyethylene glycol sorbitan monopalmitate, polyoxyethylene glycol sorbitan monostearate, N-substituted fatty acid amides, fatty acid glucamides, fatty acid alkanolamides, amine oxides, polymeric surfactants, copolymers of vinylpyrrolidone, vinyl alcohol, or vinyl acetate, alkoxylated fatty acid esters, glycerol esters or monoglycerides, and / or any combination and / or derivatives of the foregoing.

[0030] The ethoxylated fatty alcohols of fatty acids may have a degree of ethoxylation of 1-60, more preferably 2-40, most preferably 3-10.

[0031] Anionic (C6-C 18 ) Alkylbenzenesulfonate, calcium dodecylbenzenesulfonate, sodium dodecylbenzenesulfonate, amines (C6-C 18 ) Alkylbenzene sulfonate, Triethanolamine dodecylbenzene sulfonate, (C6-C 18 ) Alkyl ether sulfate, (C6-C18 ) Alkyl ethoxylated ether sulfate, (C6-C 18 ) Alkyl sulfate, lauryl ether polyethoxylated sodium sulfate, lignosulfonate, phenyl sulfonate, naphthalene sulfonate, dibutyl naphthalene sulfonate, (C6-C 18 ) Alkyl phosphate ester, (C6-C 18 ) alkoxylated sulfates, xylene sulfonates, cumene sulfonates, lignosulfonates, phenyl sulfonates, naphthalene sulfonates, dibutylnaphthalene sulfonates, alkyl polyglycol ether phosphates, polyarylphenyl ether phosphates, alkyl-sulfosuccinates, olefin sulfonates, condensation products of sulfonated naphthalene with formaldehyde, condensation products of sulfonated naphthalene with formaldehyde and phenol, optionally with urea, and condensation products of phenolsulfonic acid with formaldehyde and urea, (C6-C 18 ) can be at least one selected from the group including, but not limited to, alkoxylated phosphate esters, alkyl phosphates, alkylaryl phosphates such as tristyryl phosphate, and polycarboxylates such as polyacrylates, aryl glycosides, maleic anhydride / olefin copolymers (including alkali metal, alkaline earth, ammonium and amine salts of the foregoing), and / or any combinations and / or derivatives of the foregoing and combinations thereof.

[0032] (C2~C 26 ) alkyl lactate and / or its derivatives, (C2-C 22The various components of agricultural compositions, including alcohols, wetting agents, and nonionic and / or anionic surfactants, can chemically and physically interact to form aggregates or conformations stable enough to define syrups and / or gels as independent molecular species with physicochemical properties distinct from those of their individual components. The chemical interactions experienced between the various components include, but are not limited to, at least one of the following groups of interactions: ionic, ion-dipole, covalent, hydrogen bonding, dipole-dipole, van der Waals, dipole-induced dipole, London dispersion, π-π interactions, cation-π interactions, and anion-π interactions. Because chemical bonds are formed between two atoms or groups of atoms from the various components, the forces acting between them are such that they result in the formation of aggregates or conformations stable enough to define syrups and / or gels as independent molecular species with physicochemical properties distinct from those of their individual components.

[0033] The agricultural composition may further comprise a carboxylic acid and / or a salt thereof. Preferably, the carboxylic acid is (C2-C 22 ) may be a carboxylic acid and / or its salt.

[0034] (C2~C 22) carboxylic acids and / or salts thereof include ethanoic acid, 2-hydroxyethanoic acid, oxoethanoic acid, ethanedioic acid, propanoic acid, propenoic acid, propynoic acid, 2-hydroxypropanoic acid, 3-hydroxypropanoic acid, 2,3-dihydroxypropanoic acid, 2-oxopropanoic acid, 3-oxopropanoic acid, 2,3-oxopropanoic acid, propanedioic acid, 2-hydroxypropanedioic acid, 2-hydroxy-3-oxopropanoic acid, 2,2-dihydroxypropanedioic acid, oxopropanedioic acid, oxirane-2-carboxylic acid, butanoic acid, 2-methylpropanoic acid, (E)-but-2-enoic acid, (Z)-but-2-enoic acid, 2-methylpropenoic acid, but-3-enoic acid, but-2-enoic acid (yonic acid). acid), 2-hydroxybutanoic acid, 3-hydroxybutanoic acid, 4-hydroxybutanoic acid, 2-oxobutanoic acid, 3-oxobutanoic acid, 4-oxobutanoic acid, butanedioic acid, 2-methylpropanedioic acid, (E)-butenedioic acid, (Z)-butenedioic acid, butynedioic acid, hydroxybutanedioic acid, 2,3-dihydroxybutanedioic acid, oxobutanedioic acid, dioxobutanedioic acid, pentanoic acid, 3-methylbutanoic acid, 2-methylbutanoic acid, 2,2-dimethylpropanoic acid, 3-hydroxypentanoic acid, 4-hydroxypentanoic acid, 3-hydroxy-3-methylbutanoic acid, pentanedioic acid, 2-oxopentanedioic acid, 3-oxopentanedioic acid, furan-2-carboxylic acid, tetrahydrofuran-2-carboxylic acid, hexanoic acid, hexanedioic acid, 2,3-dimethylbutanoic acid, 3,3-dimethyl Butanoic acid, 2-hydroxypropane-1,2,3-tricarboxylic acid, prop-1-ene-1,2,3-tricarboxylic acid, 1-hydroxypropane-1,2-3-tricarboxylic acid, (2E,4E)-hexa-2,4-dienoic acid, heptanoic acid, heptanedioic acid, cyclohexanecarboxylic acid, benzenecarboxylic acid, 2-hydroxybenzoic acid, 2,2-dimethylpentanoic acid, 2,3-dimethylpentanoic acid, 2,4-dimethylpentanoic acid, 3,3-dimethylpentanoic acid, 2-ethylpentanoic acid, 3-ethylpentanoic acid, 2-methylhexanoic acid, 3-methylhexanoic acid, 2,2,3-trimethylbutanoic acid, 2-ethyl-2-methylbutanoic acid, 2-ethyl-3-methylbutanoic acid, octanoic acid, benzene-1,2-dicarboxylic acid, benzene-1,3-dicarboxylic acid, benzene-1,4-Dicarboxylic acid, 2-methylheptanoic acid, 3-methylheptanoic acid, 4-methylheptanoic acid, 5-methylheptanoic acid, 6-methylheptanoic acid, 2,2-dimethylheptanoic acid, 2,3-dimethylheptanoic acid, 2,4-dimethylheptanoic acid, 2,5-dimethylheptanoic acid, 3,3-dimethylheptanoic acid, 3,4-dimethylheptanoic acid, 3,5-dimethylheptanoic acid, 4,4-dimethylheptanoic acid, 4,5-dimethylheptanoic acid, 5,5-dimethylheptanoic acid, 2-ethylhexanoic acid ethanehexanoic acid, 3-ethanehexanoic acid, 4-ethanehexanoic acid, 5-ethanehexanoic acid, 2-octenoic acid, 3-octenoic acid, 4-octenoic acid, 5-octenoic acid, 6-octenoic acid, 7-octenoic acid, benzene-1,3,5-tricarboxylic acid, (E)-3-phenylprop-2-enoic acid, decanoic acid, decanedioic acid, undecanoic acid, dodecanoic acid, benzene-1,2,3,4,5,6-hexacarboxylic acid, tridecanoic acid, tetradecanoic acid, pentadecanoic acid, hexadecane Acid, heptadecanoic acid, octadecanoic acid, (9Z)-octadec-9-enoic acid, (9Z,12Z)-octadeca-9,12-dienoic acid, (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid, (6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid, (6Z,9Z,12Z,15Z)-octadeca-6,9,12,15-tetraenoic acid, nonadecanoic acid, eicosanoic acid, (5Z,8Z,11Z)-eicosa-5,8,11-trienoic acid, The hydroxybenzoate may be at least one selected from the group consisting of, but not limited to, (5Z,8Z,11Z,14Z)-eicosa-5,8,11,14-tetraenoic acid, (5Z,8Z,11Z,14Z,17Z)-eicosa-5,8,11,14,17-pentaenoic acid, heneicosanoic acid, docosanoic acid, (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid, and salts thereof, and / or any combination thereof.

[0035] Additionally and / or alternatively, the agricultural composition may further comprise a plant hormone, typically a stress-related plant hormone, which typically, in use, stimulates the production of defensive secondary plant metabolites in response to biotic and / or abiotic stress.

[0036] The plant hormone can be at least one selected from the group: abscisic acid, auxin, brassinosteroid, cytokinin, ethylene, gibberellin, jasmonate, jasmonic acid, salicylic acid, strigolactone, polyamine, nitrate, triacontanol, and derivatives thereof, but is not limited to these.

[0037] Additionally and / or alternatively, the agricultural composition may further comprise a secondary metabolite. The secondary metabolite may be a secondary plant metabolite, a bacterial metabolite, or a fungal metabolite. Secondary plant metabolites are a group that includes phenolics, alkaloids, saponins, terpenes, lipids, carbohydrates, and glucosinolates. Selected from The secondary plant metabolites may include, but are not limited to, at least one of the following: In certain embodiments of the present disclosure, the secondary plant metabolite is salicylic acid; The secondary bacterial metabolites may be selected from a group including polyketides, nonribosomal peptides, ribosomal peptides, glucosides, and alkaloids. Selected from Secondary fungal metabolites may include, but are not limited to, at least one of the following: itaconic acid, polyketides, nonribosomal peptides, and terpenes. Selected from In certain embodiments of the present disclosure, the secondary metabolite may include, but is not limited to, at least one of salicylic acid and / or itaconic acid.

[0038] The agricultural composition may further comprise a microorganism. In certain embodiments of the present disclosure, the microorganism may be a spore-forming microorganism.

[0039] The agricultural composition may further comprise a pheromone, an amino acid, a peptide, RNA, mRNA, siRNA, DNA, a protozoan, an oomycete and / or a yeast.

[0040] The microorganism may be selected from, but is not limited to, the groups: viruses, bacteria and fungi.

[0041] Typically, the virus may include, but is not limited to, at least one selected from any one in the group of families including baculovirus, cypovirus, and densovirus.

[0042] Typically, the virus may include, but is not limited to, at least one Baculoviridae selected from cydia pomonella granulovirus and cryptophlebia peltastica nuclear polyhedrosis virus.

[0043] Typically, the bacterium may comprise at least one selected from any of the species in the group of genera including, but not limited to, Agrobacterium, Bacillus, Burkholderia, Paenibacillus, Pseudomonas, Rhanella, Rhizobium, Saccharopolyspora, Serratia, and Streptomyces.

[0044] In certain preferred embodiments, the bacteria are Bacillus subtilis sp., Bacillus amyloliquefaciens sp., Bacillus firmus sp., Bacillus popilliae sp., Bacillus lontimorbus sp., Bacillus nakamuri sp., Bacillus pumilus sp., Bacillus sphaericus sp. Bacillus thuringiensis sp., Bacillus simplex sp., Bacillus licheniformis sp., Bacillus fastidiosus sp., Bacillus megaterium sp., Bacillus thuringiensis kurstaki sp., Bacillus thuringiensis israelensis sp., Bacillus thuringiensis aizawai sp., Bacillus thuringiensis aegyptii sp., Bacillus velezensis sp., Pseudomonas chlororaphis sp., Pseudomonas fluorescens sp., Pseudomonas protegeans sp., Streptomyces lydicus sp., Streptomyces sp., Lysobacter sp., and / or any combination thereof.

[0045] Fungi can comprise mycorrhizae.Typically, fungi can comprise but are not limited to at least one selected from any of the species in the following group of genera: Alternaria, Aureobasidium, Ampelomyces, Aschersonia, Aspergillus, Beauveria, Candida, Clonostachys, Coniothyrium, Entomophaga, Fusarium, Glomus, Hirustella, Isaria, Lecanicillium, Metarhizium, Paecilomyces, Penicillium, Pichia, Pseudozyma, Saccharomyces, Talaromyces, Trichoderma and Verticillium.

[0046] In certain embodiments, the fungus is Aureobasidium pullulans sp., Ampelomyces Quisqualis sp., Aschersonia aleyrodis sp., Aspergillus flavus sp., Beauveria bassiana sp., Beauveria brongniartii sp., Candida oleophila sp., Clonostachys rosea sp., Coniothyrium minitans sp., Cordyceps fumosorosea sp., Entomophaga maimaiga sp., Hirustella thompsonii sp., Isaria fumosorosea sp., Metarhizium anisopliae sp., Paecilomyces fumosoroseus sp., Paecilomyces lilacinus sp., Pseudozyma flocculosa sp., Saccharomyces cerevisiae sp., Trichoderma asperellum sp., Trichoderma viride sp., Trichoderma reesei sp., Trichoderma atroviride sp., Trichoderma gamsii sp., Trichoderma harzianum sp., Trichoderma polysporum sp., Trichoderma paucisporum sp., Trichoderma afroharzianu sp., Trichoderma yunnaense sp., Trichoderma evansii sp., Trichoderma hamatum sp., Trichoderma atrobrunneum sp. and Verticillium alboatrum sp., and / or any combination thereof.

[0047] Typically, the oomycete may be an oomycete of the genus Lagenidium and / or Pythium, in particular Lagenidium giganteum sp. and / or Pythium insidiosum.

[0048] The agricultural composition may further comprise a binder. Binders include polysaccharides, sucrose, fructose, saccharose, pectin, amylopectin, glycosides, glucosides (C1-C 30 ) Alkyl glycosides, (C1-C 30 ) Alkyl glucosides, gelatin, starch, modified starch, alginate, modified alginate, natural gum, modified gum, guar gum, rosin, rosin-rich tall oil, (C1-C 30 ) Alkyl cellulose, (C1-C 30 ) Salts of alkyl cellulose, carboxymethyl cellulose, salts of carboxymethyl cellulose, sodium carboxymethyl cellulose, crystalline cellulose, polyvinylpyrrolidone, cross-linked polyvinylpyrrolidone, dimethylaminoethyl-methacrylate copolymer, PVP (polyvinylpyrrolidone) / hexadecene copolymer, (C1-C 30 ) Alkyl acrylate, methyl acrylate, butyl acrylate, ethyl acrylate, 2-ethylhexyl acrylate, polyacrylate, (C1-C 30 ) may be selected from the group including, but not limited to, alkylaryl acrylates, styrene derivatives, and combinations thereof.

[0049] In a preferred embodiment of the present disclosure, the binder may be a styrene acrylic emulsion polymer.

[0050] The agricultural composition may further comprise a diluent, which may be water. The agricultural composition may further comprise an additional diluent, solvent, or co-solvent. The diluent, solvent, or co-solvent may be selected from the group including, but not limited to, alcohols, acids, fatty acids, amines, amides, ethers, esters, diesters, ketones, acetates, terpenes, sulfoxides, phenols, glycols, alkyl glycols, glycol ether esters, paraffins, hydrocarbons, tall oil, tall oil fatty acid esters, heterocyclics, aromatics, naphthenics, nitrogen compounds, sulfur compounds, halogenated hydrocarbons, and combinations thereof. Preferred solvents or co-solvents are alkyl glycols, glycol ether esters, alkyl lactates, propylene carbonate, tall oil fatty acid esters, alkylated seed oils, such as ethylated or butylated seed oils, and combinations thereof.

[0051] The agricultural composition may further comprise additives selected from the group including, but not limited to, preservatives, dispersants, wetting agents, moistening agents, spreading agents, compatibilizers, binders, fillers, adhesives, protective colloids, thickeners, thixotropic agents, penetrating agents, retention aids, sequestrants, clarifying agents, antifreeze agents, anticaking agents, hydrotropes, stabilizers, antioxidants, UV / light protectants, acidifying agents, alkaline agents, chelating agents, complexing agents, dyes, rheology modifiers, antifoaming agents, anti-drift agents, oil, water, solvents or other co-solvents, and combinations thereof.

[0052] In a preferred embodiment of the agricultural composition, the alkyl lactate is (C 10 ~C 22 ) alkyl lactate and / or its derivatives, which may be present in an amount of about 5 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural composition. 10 ~C 22 ) alkyl lactate and / or its derivatives may be present in an amount of about 7 wt.% to about 35 wt.% of the total wt.% of the formulated agricultural composition, and more preferably (C 10 ~C 22The alkyl lactate and / or its derivatives may be present in an amount of about 10 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that the ranges herein include any minimum or maximum value within said range, and all values ​​therebetween. It should be understood that wt.% in this disclosure is a percentage by weight.

[0053] In a preferred embodiment of the agricultural composition, (C2 to C 22 The alcohols may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. Preferably, the alcohols (C2 to C 22 The alcohols may be present in an amount of about 0.5 wt.% to about 10 wt.% of the total wt.% of the formulated agricultural composition, and more preferably, (C2 to C 22 The alcohol may be present in an amount of about 1 wt.% to about 5 wt.% of the total wt.% of the formulated agricultural composition. It is to be understood that the ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0054] In a preferred embodiment of the agricultural composition, the wetting agent may be present in an amount of about 1 wt.% to about 30 wt.% of the total wt.% of the formulated agricultural composition. Preferably, the wetting agent may be present in an amount of about 5 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition, and more preferably, the wetting agent may be present in an amount of about 7 wt.% to about 80 wt.% of the total wt.% of the formulated agricultural composition. Approximately 15wt.% It is to be understood that the ranges herein include any minimum or maximum value within said range, and also include every value therebetween.

[0055] In a preferred embodiment of the agricultural composition, the nonionic and / or anionic surfactants may be present in an amount of about 1 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural composition. Preferably, the nonionic and / or anionic surfactants may be present in an amount of about 5 wt.% to about 30 wt.% of the total wt.% of the formulated agricultural composition, and more preferably, the nonionic and / or anionic surfactants may be present in an amount of about 10 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0056] In a preferred exemplary embodiment, the agricultural composition includes only nonionic surfactants, excluding anionic surfactants, and the nonionic surfactant may be present in an amount of about 1 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural composition. Preferably, the nonionic surfactant may be present in an amount of about 5 wt.% to about 30 wt.% of the total wt.% of the formulated agricultural composition, and more preferably, the nonionic surfactant may be present in an amount of about 10 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within the range, and include all values ​​therebetween.

[0057] In a preferred embodiment of the agricultural composition, the carboxylic acid may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. Preferably, the carboxylic acid may be present in an amount of about 0.5 wt.% to about 10 wt.% of the total wt.% of the formulated agricultural composition, and more preferably, the carboxylic acid may be present in an amount of about 0.5 wt.% to about 5 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0058] In a preferred embodiment of the agricultural composition, the plant hormone may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. Preferably, the plant hormone may be present in an amount of about 0.5 wt.% to about 10 wt.% of the total wt.% of the formulated agricultural composition, and more preferably, the plant hormone may be present in an amount of about 0.5 wt.% to about 5 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0059] In a preferred embodiment of the agricultural composition, the secondary metabolites may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. Preferably, the secondary metabolites may be present in an amount of about 0.5 wt.% to about 10 wt.% of the total wt.% of the formulated agricultural composition, and more preferably, the secondary metabolites may be present in an amount of about 0.5 wt.% to about 5 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0060] In a preferred embodiment of the agricultural composition, the microorganisms may be present in an amount of about 1 wt.% to about 70 wt.% of the total wt.% of the formulated agricultural composition. Preferably, the microorganisms may be present in an amount of about 10 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural composition, and more preferably, the microorganisms may be present in an amount of about 25 wt.% to about 35 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and all values ​​therebetween. It should further be understood that the microorganisms may be formulated in a growth medium, and that percentages may represent dry weight percentages and / or formulated wet weight percentages including the growth medium.

[0061] In a preferred embodiment of the agricultural composition, the binder may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. Preferably, the binder may be present in an amount of about 1 wt.% to about 15 wt.% of the total wt.% of the formulated agricultural composition, and more preferably, the binder may be present in an amount of about 2 wt.% to about 10 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0062] In preferred embodiments of the agricultural composition, the additive may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. Preferably, the additive may be present in an amount of about 0.5 wt.% to about 15 wt.% of the total wt.% of the formulated agricultural composition, and more preferably, the additive may be present in an amount of about 1 wt.% to about 10 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0063] In preferred embodiments of the agricultural composition, the diluent may be present in an amount of about 1 wt.% to about 80 wt.% of the total wt.% of the formulated agricultural composition. Preferably, the diluent may be present in an amount of about 10 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural composition, and more preferably, the diluent may be present in an amount of about 20 wt.% to about 30 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0064] The agricultural compositions of the present disclosure may be provided as at least one of the group including, but not limited to, plant protection products, adjuvants, soil conditioners, biostimulants, seed treatments, fertilizers, insect growth regulators, plant growth regulators, and elicitors.

[0065] The agricultural composition may further comprise at least one of the group including, but not limited to, plant protection products, adjuvants, soil conditioners, biostimulants, seed treatments, fertilizers, insect growth regulators, plant growth regulators, and elicitors.

[0066] In a preferred embodiment of the present disclosure, the agricultural composition of the present disclosure is provided as a plant protection product, which may be an insecticide, pesticide, acaricide, miticide, ovicide, herbicide, fungicide, viricide, nematicide, and nematicide, preferably, the plant protection product may be an insecticide and / or fungicide, more preferably, the plant protection product may be a nematicide and / or nematicide.

[0067] In another preferred embodiment of the present disclosure, the agricultural composition of the present disclosure is provided as an adjuvant, soil conditioner, biostimulant, seed treatment, fertilizer, insect growth regulator, plant regulator and / or elicitor.

[0068] In certain exemplary embodiments of the first aspect of the present disclosure, there is provided an agricultural composition comprising lactyl lauryl lactate and / or lauryl lactate and / or myristyl lactate and / or cetyl lactate and / or combinations of the foregoing; and octan-2-ol; and glycerin; and polyoxyethylene sorbitan monolaurate.

[0069] The agricultural composition may further comprise at least one of a carboxylic acid, a plant hormone, a secondary metabolite, a microorganism, a binder, an anionic surfactant, and a diluent, as described above in accordance with the first aspect of the present disclosure herein above.

[0070] In certain examples of embodiments, the secondary metabolites are salicylic acid and / or itaconic acid.

[0071] According to a second aspect of the present disclosure, (C2 to C 26 ) alkyl lactate and / or its derivatives; (C2 to C 22 )alcohol; a wetting agent according to the first aspect of the present disclosure; a nonionic and / or anionic surfactant according to the first aspect of the present disclosure; and The binder according to the first aspect of the present disclosure An agricultural composition is provided, which is a carrier composition comprising:

[0072] (C2~C 26 ) Alkyl lactate is (C 10 ~C 22 ) alkyl lactate and / or its derivatives. 10 ~C 22 ) alkyl lactate and / or its derivatives, (C2-C 22 The various components of the carrier composition, including alcohols, humectants, nonionic and / or anionic surfactants, and binders, can chemically and physically interact to form aggregates or conformations stable enough to define syrups and / or gels as independent molecular species with physicochemical properties distinct from their individual components. The chemical interactions experienced between the various components include, but are not limited to, at least one of the following groups of interactions: ionic, ion-dipole, covalent, hydrogen bonding, dipole-dipole, van der Waals, dipole-induced dipole, London dispersion, π-π interactions, cation-π interactions, and anion-π interactions. Because chemical bonds are formed between two atoms or groups of atoms from the various components, the forces acting between them are such that they result in the formation of aggregates or conformations stable enough to define syrups and / or gels as independent molecular species with physicochemical properties distinct from their individual components.

[0073] The carrier composition may further comprise a diluent, which may be water and / or a co-solvent. The carrier composition may further comprise an additive as described in the first aspect of the present disclosure.

[0074] The carrier composition may be provided as a syrup and / or a gel. The carrier composition is, inter alia, an adjuvant for tank mixes in agricultural applications, an adjuvant for seed treatment, an in-can additive for plant protection products, an in-can additive for fertilizers, an in-can additive for soil conditioners, an in-can additive for biostimulants, an in-can additive for seed treatment products. additive , may be provided as a soil conditioner product for in-furrow application.

[0075] The carrier composition may be loaded with an active ingredient and / or a biocontrol agent and / or a fertilizer and / or a biostimulant and / or an elicitor and / or a plant growth regulator and / or an insect repellent to provide a loaded agricultural carrier composition.

[0076] Biocontrol agents may include carboxylic acids, plant hormones, secondary metabolites, and / or microorganisms.

[0077] The active ingredient may be a plant protection product, which may include at least one of the group including, but not limited to, insecticides, pesticides, acaricides, miticides, ovicides, herbicides, fungicides, virucides, nematicides, nematicides, and insect growth regulators.

[0078] The biocontrol agent may comprise a microorganism described in the first aspect of the present disclosure and / or a plant hormone described in the first aspect of the present disclosure and / or a carboxylic acid described in the first aspect of the present disclosure and / or a secondary metabolite described in the first aspect of the present disclosure.

[0079] In a preferred embodiment of the agricultural carrier composition, (C2 to C 26 ) Alkyl lactate is (C 10 ~C 22 ) alkyl lactate and / or its derivatives, which may be present in an amount of about 5 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural carrier composition. Preferably, (C 10 ~C 22) alkyl lactate and / or its derivatives may be present in an amount of about 7 wt.% to about 35 wt.% of the total wt.% of the formulated carrier agricultural composition, and more preferably (C 10 ~C 22 ) The alkyl lactate and / or its derivatives may be present in an amount of about 10 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural carrier composition. It should be understood that the ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0080] In a preferred embodiment of the agricultural carrier composition, (C2 to C 22 The alcohol may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural carrier composition. Preferably, the alcohol is (C2 to C 22 The alcohol may be present in an amount of about 0.5 wt.% to about 10 wt.% of the total wt.% of the formulated agricultural carrier composition, and more preferably, (C2 to C 22 The alcohol may be present in an amount of about 1 wt.% to about 5 wt.% of the total wt.% of the formulated agricultural carrier composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0081] In a preferred embodiment of the agricultural carrier composition, the wetting agent may be present in an amount of about 1 wt.% to about 30 wt.% of the total wt.% of the formulated agricultural carrier composition. Preferably, the wetting agent may be present in an amount of about 5 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural carrier composition, and more preferably, the wetting agent may be present in an amount of about 7 wt.% to about 15 wt.% of the total wt.% of the formulated agricultural carrier composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0082] In a preferred embodiment of the agricultural carrier composition, the nonionic and / or anionic surfactant may be present in an amount of about 1 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural carrier composition. Preferably, the nonionic and / or anionic surfactant may be present in an amount of about 5 wt.% to about 30 wt.% of the total wt.% of the formulated agricultural carrier composition, and more preferably, the nonionic and / or anionic surfactant may be present in an amount of about 10 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural carrier composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0083] In a preferred exemplary embodiment, the agricultural carrier composition includes only nonionic surfactants, excluding anionic surfactants, and the nonionic surfactant may be present in an amount of about 1 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural carrier composition. Preferably, the nonionic surfactant may be present in an amount of about 5 wt.% to about 30 wt.% of the total wt.% of the formulated agricultural carrier composition, and more preferably, the nonionic surfactant may be present in an amount of about 10 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural carrier composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0084] In a preferred embodiment of the agricultural carrier composition, the binder may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural carrier composition. Preferably, the binder may be present in an amount of about 1 wt.% to about 15 wt.% of the total wt.% of the formulated agricultural carrier composition, and more preferably, the binder may be present in an amount of about 2 wt.% to about 10 wt.% of the total wt.% of the formulated agricultural carrier composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0085] In a preferred embodiment of the agricultural carrier composition, the diluent may be present in an amount of about 1 wt.% to about 80 wt.% of the total wt.% of the formulated agricultural carrier composition. Preferably, the diluent may be present in an amount of about 10 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural carrier composition, and more preferably, the diluent may be present in an amount of about 20 wt.% to about 30 wt.% of the total wt.% of the formulated agricultural carrier composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0086] In a preferred embodiment, the agricultural carrier composition is loaded with a carboxylic acid, which may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated, loaded agricultural carrier composition. Preferably, the carboxylic acid may be present in an amount of about 0.5 wt.% to about 10 wt.% of the total wt.% of the formulated, loaded agricultural carrier composition, and more preferably, the carboxylic acid may be present in an amount of about 0.5 wt.% to about 5 wt.% of the total wt.% of the formulated, loaded agricultural carrier composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0087] In a preferred embodiment, the agricultural carrier composition is loaded with a plant hormone, which may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated, loaded agricultural carrier composition. Preferably, the plant hormone may be present in an amount of about 0.5 wt.% to about 10 wt.% of the total wt.% of the formulated, loaded agricultural carrier composition, and more preferably, the plant hormone may be present in an amount of about 0.5 wt.% to about 5 wt.% of the total wt.% of the formulated, loaded agricultural carrier composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0088] In a preferred embodiment, the agricultural carrier composition is loaded with secondary metabolites, which may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated, loaded agricultural carrier composition. Preferably, the secondary metabolites may be present in an amount of about 0.5 wt.% to about 10 wt.% of the total wt.% of the formulated, loaded agricultural carrier composition, and more preferably, the secondary metabolites may be present in an amount of about 0.5 wt.% to about 5 wt.% of the total wt.% of the formulated, loaded agricultural carrier composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0089] In a preferred embodiment, the agricultural carrier composition is loaded with microorganisms, which may be present in an amount of about 1 wt.% to about 70 wt.% of the total wt.% of the formulated, loaded agricultural carrier composition. Preferably, the microorganisms may be present in an amount of about 10 wt.% to about 50 wt.% of the total wt.% of the formulated, loaded agricultural carrier composition, and more preferably, the microorganisms may be present in an amount of about 25 wt.% to about 35 wt.% of the total wt.% of the formulated, loaded agricultural carrier composition. It should be understood that ranges herein include any minimum or maximum value within said range, and all values ​​therebetween. It should further be understood that the microorganisms may be formulated in a growth medium, and percentages may represent dry weight percentages and / or formulated wet weight percentages, including the growth medium.

[0090] In preferred embodiments of the agricultural carrier composition (loaded or unloaded), the additive may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural carrier composition. Preferably, the additive may be present in an amount of about 0.5 wt.% to about 15 wt.% of the total wt.% of the formulated agricultural composition, and more preferably, the additive may be present in an amount of about 1 wt.% to about 10 wt.% of the total wt.% of the formulated agricultural carrier composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0091] Additionally and / or optionally, the agricultural carrier composition (loaded or unloaded) may further comprise at least one of the group including, but not limited to, co-solvents and other additives, which may be included to tailor to the desired use as an in-can additive or final commercial product.

[0092] It should be understood that the carrier composition can be applied in a can mixed with the plant protection product, or can be applied to a tank mix containing the plant protection product, or can be applied adjacent to the plant protection product in an in-furrow application to enhance or improve the performance of the plant protection product, promote the desired outcome of the plant protection product, and increase the plant response to the plant protection product against the pest or disease under control.

[0093] The composition according to the first and / or second aspect of the present disclosure may be provided as at least one of the group including, but not limited to, a plant protection product, an adjuvant, a soil conditioner, a biostimulant, a seed treatment, a fertilizer, an insect growth regulator, a plant growth regulator, and an elicitor.

[0094] In a preferred embodiment, the composition according to the first and / or second aspect of the present disclosure may be a plant protection product, including, but not limited to, insecticides, pesticides, miticides, acaricides, ovicides, herbicides, fungicides, virucides, and nematicides.

[0095] According to a third aspect of the present disclosure, there is provided a method for producing the agricultural composition of the first aspect, comprising the steps of: (C2-C3) to promote chemical-physical interactions that result in aggregates or conformations that are stable enough to define a syrup and / or gel. 26 ) alkyl lactate and / or its derivatives, (C2-C 22 ) providing with an alcohol, a wetting agent; and a nonionic and / or anionic surfactant. A method is provided, comprising:

[0096] Syrups and / or gels are independent molecular species with physicochemical properties distinct from their individual components. Syrups and / or gels are driven by chemical interactions experienced between various factors, including, but not limited to, at least one of the following groups of interactions: ionic, ion-dipole, covalent, hydrogen bonding, dipole-dipole, van der Waals, dipole-induced dipole, London dispersion, π-π interactions, cation-π interactions, and anion-π interactions. Because chemical bonds are formed between two atoms or groups of atoms from various factors, the forces acting between them are such that they result in the formation of aggregates or conformations stable enough to define syrups and / or gels, where the independent molecular species have physicochemical properties distinct from their individual components.

[0097] The method may include the additional step of providing carboxylic acids and / or plant hormones and / or secondary metabolites before and / or after forming the syrup and / or gel.

[0098] The method may include the additional step of providing the microorganisms before and / or after forming the syrup and / or gel.

[0099] The method may include the additional step of providing a plant protection product before and / or after forming the syrup and / or gel.

[0100] The method may include the additional step of providing a binder before and / or after forming the syrup and / or gel.

[0101] The method may include the additional step of providing water and / or a co-solvent before and / or after forming the syrup and / or gel.

[0102] According to a fourth aspect of the present disclosure, there is provided a method of producing the carrier composition of the second aspect, comprising the steps of: (C2-C3) to promote chemical-physical interactions that result in aggregates or conformations that are stable enough to define a syrup and / or gel. 26 ) alkyl lactate and / or its derivatives, (C2-C 22 ) providing with alcohol, wetting agent; nonionic and / or anionic surfactant and binder. A method is provided, comprising:

[0103] Syrups and / or gels are independent molecular species with physicochemical properties distinct from their individual components. Syrups and / or gels are driven by chemical interactions experienced between various factors, including, but not limited to, at least one of the following groups of interactions: ionic, ion-dipole, covalent, hydrogen bonding, dipole-dipole, van der Waals, dipole-induced dipole, London dispersion, π-π interactions, cation-π interactions, and anion-π interactions. Because chemical bonds are formed between two atoms or groups of atoms from various factors, the forces acting between them are such that they result in the formation of aggregates or conformations stable enough to define syrups and / or gels, where the independent molecular species have physicochemical properties distinct from their individual components.

[0104] The method may include the additional step of providing water and / or other co-solvents before and / or after forming the syrup and / or gel.

[0105] The method may include the additional step of providing carboxylic acids and / or plant hormones and / or secondary metabolites and / or microorganisms and / or biocontrol agents and / or plant protection products before and / or after forming the syrup and / or gel to provide a loaded agricultural carrier composition.

[0106] There is further provided an agricultural composition according to the first aspect and / or a carrier composition according to the second aspect and / or a method of producing according to the third aspect and / or a method of producing according to the fourth aspect, all substantially as described, illustrated and / or exemplified herein with reference to any one of the following drawings and / or examples.

[0107] Embodiments of the present disclosure will now be described, by way of example only, with reference to the accompanying drawings, in which: [Brief explanation of the drawings]

[0108] [Figure 1] Figure 1 shows the nematicidal efficacy of selected bacteria when applied alone or mixed with an unloaded carrier composition (UCC) according to the present disclosure. [Figure 2] It is shown that the loading of secondary metabolites within UCC improves the overall efficacy as a nematicide when compared to UCC on its own. [Figure 3] 1 shows a preferred embodiment of a loaded carrier composition (pLCC, also referred to as OR-501) according to the present disclosure, which exhibits superior nematicidal efficacy when compared to commercially available products. [Figure 4] 1 shows the number of nematode eggs and second stage nymph nematodes per gram of root after utilizing a loaded carrier composition according to the present disclosure (pLCC, also known as OR-501) in a potted field trial. [Figure 5] Figure 1 shows a bar graph showing the mean (±SEM) mortality of Pratylenchus penetrans in response to different test compositions - complementary nematicidal laboratory test - Portugal. [Figure 6] Percentage of mites killed 24 hours after treatment application is shown - Complementary insecticidal laboratory test - South Africa. [Figure 7] Percentage of mites killed 48 hours after treatment application is shown - Complementary insecticidal laboratory test - South Africa. [Figure 8]Bar graph showing the severity of root knots visually assessed on a scale of 0 to 10 (0: completely healthy root system, no infection to 10: all heavily nodulated roots, root system and plant usually not killed). Nematicide field trials - Spain. [Figure 9] Bar graph of J2 number / 100cm3 soil for different treatments. Nematicide field trials - Spain. [Figure 10] Bar graph showing yield / plot (tonnes / ha) for the different treatments recorded at the end of the trial. Nematicide field trials - Spain. [Figure 11] Figure 1 shows a bar graph of the average fruit weight (g / fruit) of the different treatments recorded at the end of the trial. Nematicide field trial - Spain. [Figure 12] Figure 1 shows a bar graph of the number of saleable fruits (grams / fruit) for the different treatments recorded at the end of the trial. Nematicide field trial - Spain. [Figure 13] Summary data for healthy and infected melons, healthy and infected roots, and bar graphs of the percentage of healthy and infected melons and roots for different treatments on melons controlling Meloidogyne incognita. Data were recorded at the end of the trial during harvest. Commercial Greenhouse Nematicide Field Trial - Shandong Province - China [Figure 14] Photographs of examples of healthy and infected roots and healthy and infected melons after harvest are shown. Harvested melons and roots refer to treatment with composition ORO-501 [also referred to as OR-501 or B-017-001 (Bacillus amyloliquefaciens 20% + UCCa 80%)], a standard treatment for melons controlling Meloidogyne incognita - commercial greenhouse nematicide field trial - Shandong Province - China. DETAILED DESCRIPTION OF THE INVENTION

[0109] Detailed Description of the Disclosure A summary of the present disclosure, including all aspects thereof, is repeated below by reference only to avoid repetition.Specific, but non-limiting, embodiments of the present disclosure are described below.

[0110] According to a first aspect of the present disclosure, alkyl lactate and / or its derivatives (C2 to C 22 ) An agricultural composition is provided that includes an alcohol, a wetting agent, and a nonionic and / or anionic surfactant.

[0111] Typically, (C2~C 26 ) Alkyl lactate is (C 10 ~C 22 ) alkyl lactate and / or its derivatives.

[0112] (C2~C 26 ) The alkyl lactate and / or derivatives thereof can be at least one selected from the group including, but not limited to, ethyl lactate, propyl lactate, butyl lactate, pentyl lactate, hexyl lactate, heptyl lactate, octyl lactate, nonyl lactate, decyl lactate, undecyl lactate, dodecyl lactate, tridecyl lactate, tetradecyl lactate, pentadecyl lactate, hexadecyl lactate, heptadecyl lactate, octadecyl lactate, nonadecyl lactate, eicosyl lactate, heneicosyl lactate, and docosyl lactate, and / or derivatives of the foregoing.

[0113] Alkyl lactate is (C 10 ~C 22 ) alkyl lactate or any combination and / or derivative of the foregoing and combinations thereof. Preferably, (C 10 ~C 22 ) The alkyl lactate and / or its derivatives may be at least one selected from the group including, but not limited to, lauryl lactate (dodecyl lactate), myristyl lactate (tetradecyl lactate), cetyl lactate (hexadecyl lactate), and lactyl lauryl lactate.

[0114] (C2~C 26 ) Alkyl lactate and / or its derivatives are (C2-C 26) alkyl lactyl lactate and / or its derivatives.

[0115] (C2~C 26 ) The alkyl lactyl lactate and / or its derivatives may be at least one selected from the group including, but not limited to, ethyl lactyl lactate, propyl lactyl lactate, butyl lactate, pentyl lactyl lactate, hexyl lactyl lactate, heptyl lactate, octyl lactyl lactate, nonyl lactyl lactate, decyl lactate, undecyl lactate, dodecyl lactate, tridecyl lactate, tetradecyl lactate, pentadecyl lactate, hexadecyl lactyl lactate, heptadecyl lactate, octadecyl lactate, nonadecyl lactate, eicosyl lactate and / or derivatives thereof.

[0116] (C2~C 26 ) Lactyl alkyl lactate and / or its derivatives are (C 10 ~C 22 ) alkyl lactylate and / or its derivatives. Preferably, (C 10 ~C 20 ) The lactyl alkyl lactylate can be lauryl lactylate.

[0117] Typically, (C2~C 22 ) Alcohols include monoalcohols, diols, triols, tetraols, pentaols, hexaols, alkyl alcohols, alkenols, alkynols, primary, secondary, tertiary, aromatic, cyclic, alicyclic, unbranched, branched, saturated, and unsaturated alcohols, and / or any combination and / or derivatives of the foregoing. In certain embodiments, (C2-C 22 ) Alcohols include ethanol, propanol, propan-2-ol, butanol, butan-2-ol, pentanol, pentan-2-ol, pentan-3-ol, hexanol, hexane-2-ol, hexane-3-ol, heptanol, heptan-2-ol, heptan-3-ol, heptan-4-ol, octanol, octan-2-ol, Octan-3-ol, Octan-4-ol, 2-ethylhexanol, Nonanol, Nonan-2-ol, Nonan-3-ol, Nonan-4-ol, Nonan-5-ol, Decanol, Decan-2-ol, Decan-3-ol, Decan-4-ol, Decan-5-ol, Undecanol, Undecan-2-ol, Undecan-3-ol, Undecan-4-ol, Undecan-5-ol, Undecan-6-ol, Dodecanol, Dodecan-2-ol, Dodecan-3-ol, Dodecan-4-ol, Dodecan-5-ol, Dodecan-6-ol, Tridecanol nol, tridecan-2-ol, tridecan-3-ol, tridecan-4-ol, tridecan-5-ol, tridecan-6-ol, tridecan-7-ol, tetradecanol, tetradecan-2-ol, tetradecan-3-ol, tetradecan-4-ol, tetradecan-5-ol, tetradecan-6-ol, tetradecan-7-ol, pentadecanol, pentadecane-2-ol, pentadecane-3-ol, pentadecane-4-ol, pentadecane-5-ol, pentadecane-6-ol, pentadecane-7-ol, Pentadecane-8-ol, hexadecanol, hexadecan-2-ol, hexadecan-3-ol, hexadecan-4-ol, hexadecan-5-ol, hexadecan-6-ol, hexadecan-7-ol, hexadecan-8-ol, heptadecanol, heptadecan-2-ol, heptadecan-3-ol, heptadecan-4-ol, heptadecan-5-ol, heptadecan-6-ol, heptadecan-7-ol, heptadecan-8-ol, heptadecan-9-ol, octadecanol, octadecan-2-ol, octadecan- tadecan-3-ol, octadecan-4-ol, octadecan-5-ol, octadecan-6-ol, octadecan-7-ol, octadecan-8-ol, octadecan-9-ol, nonadecanol, nonadecan-2-ol, nonadecan-3-ol, nonadecan-4-ol, nonadecan-5-ol, nonadecan-6-ol, nonadecan-7-ol, nonadecan-8-ol, nonadecan-9-ol, nonadecan-10-ol, eicosanol, eicosan-2-ol, eicosan-3-ol, eicosan-4-ol,Eicosan-5-ol, eicosan-6-ol, eicosan-7-ol, eicosan-8-ol, eicosan-9-ol, eicosan-10-ol, heneicosanol, heneicosan-2-ol, heneicosan-3-ol, heneicosan-4-ol, heneicosan-5-ol, heneicosan-6-ol, heneicosan-7-ol, heneicosan-8-ol, heneicosan-9-ol, heneicosan-10 The hydroxybenzoate may be at least one selected from the group including, but not limited to, heneicosan-11-ol, docosanol, docosan-2-ol, docosan-3-ol, docosan-4-ol, docosan-5-ol, docosan-6-ol, docosan-7-ol, docosan-8-ol, docosan-9-ol, docosan-10-ol and docosan-11-ol, and / or any combination and / or derivative of the foregoing.

[0118] In a preferred exemplary embodiment of the present disclosure, (C2 to C 22 ) The alcohol is octan-2-ol.

[0119] Typically, the humectant is glycerin, glycerol or its alkyl ethers, (C2-C 30 ) Alkene glycol, propylene glycol, polypropylene glycol or its alkyl ether, sorbitol, mannitol, dulcitol and / or polyol, alkyl glycoside, linear (C4-C 18 ) Alkyl (poly)glycosides, branched chain (C4-C 18 ) Alkyl (poly)glycosides, linear (C4-C 18 ) Alkyl (poly)glucosides, branched chain (C4-C 18 ) alkyl (poly)glucosides, aryl glycosides, and / or any combinations and / or derivatives of the foregoing.

[0120] In a preferred exemplary embodiment of the present disclosure, the humectant is glycerin. Typically, nonionics are natural and / or synthetic (C8-C 22 ) alkoxylated fatty alcohols, (C8-C 22 ) Ethoxylated fatty alcohols, (C8-C 22 ) Propoxylated fatty alcohols, (C8-C 22 ) Ethoxylated and propoxylated fatty alcohols, (C6-C 22 ) Alkoxylated fatty acids, (C6-C 22 ) Ethoxylated fatty acids, (C6-C 22 ) Propoxylated fatty acids, EO-PO(C6-C 22 ) Ethoxylated and propoxylated fatty acids, linear (C4-C 10 ) Alkyl (poly)glycosides, branched chain (C4-C 10 ) alkyl (poly)glycosides; and at least one selected from the group including, but not limited to, alkoxylated sorbitan fatty acid esters, alkoxylated sorbitol fatty acid esters, ethoxylated sorbitan fatty acid esters, ethoxylated sorbitol fatty acid esters, polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monolaurate, polyoxyethylene glycol sorbitan monolaurate, polyoxyethylene glycol sorbitan monopalmitate, polyoxyethylene glycol sorbitan monostearate, N-substituted fatty acid amides, fatty acid glucamides, fatty acid alkanolamides, amine oxides, polymeric surfactants, copolymers of vinylpyrrolidone, vinyl alcohol, or vinyl acetate, alkoxylated fatty acid esters, glycerol esters or monoglycerides, and / or any combination and / or derivatives of the foregoing.

[0121] In a preferred exemplary embodiment of the present disclosure, the non-ionic surfactant is polyoxyethylene sorbitan monolaurate.

[0122] Typically, the anionic 18) Alkylbenzenesulfonate, calcium dodecylbenzenesulfonate, sodium dodecylbenzenesulfonate, amines (C6-C 18 ) Alkylbenzene sulfonate, Triethanolamine dodecylbenzene sulfonate, (C6-C 18 ) Alkyl ether sulfate, (C6-C 18 ) Alkyl ethoxylated ether sulfate, (C6-C 18 ) Alkyl sulfate, lauryl ether polyethoxylated sodium sulfate, lignosulfonate, phenyl sulfonate, naphthalene sulfonate, dibutyl naphthalene sulfonate, (C6-C 18 ) Alkyl phosphate ester, (C6-C 18 ) alkoxylated sulfates, xylene sulfonates, cumene sulfonates, lignosulfonates, phenyl sulfonates, naphthalene sulfonates, dibutylnaphthalene sulfonates, alkyl polyglycol ether phosphates, polyarylphenyl ether phosphates, alkyl-sulfosuccinates, olefin sulfonates, condensation products of sulfonated naphthalene with formaldehyde, condensation products of sulfonated naphthalene with formaldehyde and phenol, optionally with urea, and condensation products of phenolsulfonic acid with formaldehyde and urea, (C6-C 18 ) can be at least one selected from the group including, but not limited to, alkoxylated phosphate esters, alkyl phosphates, alkylaryl phosphates such as tristyryl phosphate, and polycarboxylates such as polyacrylates, aryl glycosides, maleic anhydride / olefin copolymers (including alkali metal, alkaline earth, ammonium and amine salts of the foregoing), and / or any combinations and / or derivatives of the foregoing and combinations thereof.

[0123] In a preferred exemplary embodiment of the present disclosure, the anionic surfactant is a lignosulfonate.

[0124] Typically, the agricultural composition further comprises a carboxylic acid and / or a salt thereof. Preferably, the carboxylic acid is a carboxylic acid selected from the group consisting of (C2 to C6) 22 ) may be a carboxylic acid and / or its salt.

[0125] Additionally and / or alternatively, the agricultural composition may further comprise a plant hormone, which may be at least one selected from the group including, but not limited to, abscisic acid, auxin, brassinosteroid, cytokinin, ethylene, gibberellin, jasmonate, jasmonic acid, salicylic acid, strigolactone, polyamine, nitrate, triacontanol, and derivatives thereof.

[0126] In a preferred exemplary embodiment of the present disclosure, the plant hormone is salicylic acid. Additionally and / or alternatively, the agricultural composition may further comprise a secondary metabolite. The secondary metabolite may be a secondary plant, bacterial, or fungal metabolite. The secondary plant metabolite may comprise at least one group including, but not limited to, phenolics, alkaloids, saponins, terpenes, lipids, carbohydrates, and glucosinolates. In certain embodiments of the present disclosure, the secondary plant metabolite is salicylic acid. The secondary bacterial metabolite may comprise at least one group including, but not limited to, polyketides, nonribosomal peptides, ribosomal peptides, glucosides, and alkaloids. The secondary fungal metabolite may comprise at least one group including, but not limited to, itaconic acid, polyketides, nonribosomal peptides, and terpenes. In certain embodiments of the present disclosure, the secondary metabolite is salicylic acid and / or itaconic acid.

[0127] Typically, the agricultural composition further comprises a microorganism. In certain embodiments of the present disclosure, the microorganism may be a spore-forming microorganism.

[0128] The agricultural composition may further comprise a pheromone, an amino acid, a peptide, RNA, mRNA, siRNA, DNA, a protozoan, an oomycete and / or a yeast.

[0129] The microorganism may be selected from, but is not limited to, the groups: viruses, bacteria and fungi.

[0130] Typically, the virus may include, but is not limited to, at least one selected from any one in the group of families including baculovirus, cypovirus, and densovirus.

[0131] Typically, the virus may be at least one selected from, but not limited to, cydia pomonella granulovirus and cryptophlebia peltastica nuclear polyhedrosis virus.

[0132] Typically, the bacterium may comprise at least one selected from any of the species in the group of genera including, but not limited to, Agrobacterium, Bacillus, Burkholderia, Paenibacillus, Pseudomonas, Rhanella, Rhizobium, Saccharopolyspora, Serratia, and Streptomyces.

[0133] In certain preferred embodiments, the bacteria are Bacillus subtilis sp., Bacillus amyloliquefaciens sp., Bacillus firmus sp., Bacillus popilliae sp., Bacillus lontimorbus sp., Bacillus nakamuri sp., Bacillus pumilus sp., Bacillus sphaericus sp., Bacillus thuringiensis sp., Bacillus simplex sp., Bacillus simplex sp. licheniformis sp., Bacillus fastidiosus sp., Bacillus megaterium sp., Bacillus thuringiensis kurstaki sp., Bacillus thuringiensis israelensis sp., Bacillus thuringiensis aizawai sp., Bacillus thuringiensis aegyptii sp., Bacillus velezensis sp., Pseudomonas chlororaphis sp., Pseudomonas fluorescens sp., Pseudomonas protegeans sp., Pseudomonas sp., Streptomyces lydicus sp., Streptomyces sp., Lysobacter sp., and / or any combination thereof.

[0134] Fungi can comprise mycorrhizae.Typically, fungi can comprise at least one selected from the following genera: Alternaria, Aureobasidium, Ampelomyces, Aschersonia, Aspergillus, Beauveria, Candida, Clonostachys, Coniothyrium, Entomophaga, Fusarium, Glomus, Hirustella, Isaria, Lecanicillium, Metarhizium, Paecilomyces, Penicillium, Pichia, Pseudozyma, Saccharomyces, Talaromyces, Trichoderma and Verticillium.

[0135] Aureobasidium pullulans sp., Ampelomyces Quisqualis sp., Aschersia aleyrodis sp., Aspergillus flavus sp., Beauveria bassiana sp brongniartii sp. Candida oleophila sp. Clonostachys rosea sp. Coniothyrium minitans sp. Cordyceps fumosorosea sp. Entomophaga maimaiga sp. Hirustella thompsonii sp. Isaria fumosorosea sp. Metarhizium anisopliae sp. Paecilomyces fumosoroseus sp. Paecilomyces lilacinus sp. Pseudozyma flocculosa sp. Saccharomyces cerevisiae sp. Trichoderma asperellum sp. Trichoderma viride sp. Trichoderma reesei sp sp., Trichoderma gamsii sp., Trichoderma harzianum sp., Trichoderma polysporum sp., Trichoderma paucisporum sp., Trichoderma afroharzianu sp., Trichoderma yunnaense sp., Trichoderma evansii sp., Trichoderma hamatum sp., Trichoderma atrobrunneum sp., Verticillium alboatrum The spをaddition is very strong and 1.0.

[0136] Typically, the oomycete may be an oomycete of the genus Lagenidium and / or Pythium, in particular Lagenidium giganteum sp. and / or Pythium insidiosum.

[0137] In preferred exemplary embodiments of the present disclosure, the microorganism is a bacterium from the genus Bacillus and / or Pseudomonas. In certain preferred embodiments, the bacterium may be Bacillus subtilis sp., Bacillus amyloliquefaciens sp., Bacillus firmus sp., Bacillus thuringiensis sp., Bacillus simplex sp., Bacillus licheniformis sp., Bacillus megaterium sp., Bacillus velezensis sp., and / or Pseudomonas fluorescens sp., Pseudomonas protegeans sp., in isolated form as a single species or a combination of species or strains thereof.

[0138] In certain embodiments, the fungus may be Tricoderma harzianum sp., Tricoderma asperellum sp., Trichoderma viride sp., Trichoderma reesei sp., and / or Paecilomyces lilacinus sp., and the species may be in isolated form alone or in combinations of strains thereof. In certain embodiments of the present disclosure, the agricultural composition further comprises a binder. Binders include polysaccharides, sucrose, fructose, saccharose, pectin, amylopectin, glycosides, glucosides (C1-C 30 ) Alkyl glycosides, (C1-C 30 ) Alkyl glucosides, gelatin, starch, modified starch, alginate, modified alginate, natural gum, modified gum, guar gum, rosin, rosin-rich tall oil, (C1-C 30 ) Alkyl cellulose, (C1-C 30) Salts of alkyl cellulose, carboxymethyl cellulose, salts of carboxymethyl cellulose, sodium carboxymethyl cellulose, crystalline cellulose, polyvinylpyrrolidone, crosslinked polyvinylpyrrolidone, dimethylaminoethyl-methacrylate copolymer, PVP / hexadecene copolymer, (C1-C 30 ) Alkyl acrylate, methyl acrylate, butyl acrylate, ethyl acrylate, 2-ethylhexyl acrylate, polyacrylate, (C1-C 30 ) alkylaryl acrylates, and styrene derivatives, and combinations thereof.

[0139] In a preferred embodiment of the present disclosure, the binder is a styrene acrylic emulsion polymer.

[0140] In certain embodiments of the present disclosure, the agricultural composition further comprises a diluent. The diluent may be water.

[0141] It is indicated that the agricultural composition may further comprise additives selected from the group including, but not limited to, preservatives, clarifying agents, antifreeze agents, hydrotropes, stabilizers, antioxidants, acidifying agents, chelating agents, complexing agents, dyes, rheology modifiers, antifoaming agents, anti-drift agents, oils or other solvents, and combinations thereof.

[0142] In a preferred embodiment of the agricultural composition, (C 10 ~C 20 ) alkyl lactate (C2-C 26 ) The alkyl lactate, and / or derivatives thereof, may be present in an amount of about 5 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural composition. It is to be understood that the ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0143] In a preferred embodiment of the agricultural composition, (C2 to C 22The alcohol may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. It is to be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0144] In preferred embodiments of the agricultural composition, the wetting agent may be present in an amount of about 1 wt.% to about 30 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0145] In preferred embodiments of the agricultural composition, the nonionic and / or anionic surfactants may be present in an amount of about 1 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0146] In a preferred exemplary embodiment, the agricultural composition includes only nonionic surfactants to the exclusion of anionic surfactants, and the nonionic surfactants may be present in an amount of about 1 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0147] In a preferred embodiment of the agricultural composition, the carboxylic acid may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0148] In a preferred embodiment of the agricultural composition, the plant hormone may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0149] In a preferred embodiment, the agricultural carrier composition is loaded with secondary metabolites, which may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated loaded agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0150] In preferred embodiments of the agricultural composition, the microorganisms may be present in an amount of about 1 wt.% to about 70 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween. It should further be understood that the microorganisms may be formulated in a growth medium, and the percentages may represent dry weight percentages and / or formulated wet weight percentages including the growth medium.

[0151] In preferred embodiments of the agricultural composition, the binder may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0152] In preferred embodiments of the agricultural composition, the additive may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0153] In preferred embodiments of the agricultural composition, the diluent may be present in an amount of about 1 wt.% to about 80 wt.% of the total wt.% of the formulated agricultural composition. It should be understood that ranges herein include any minimum or maximum value within said range, and include all values ​​therebetween.

[0154] In a preferred exemplary embodiment, the agricultural composition comprises lactyl lauryl lactylate, octan-2-ol, glycerin, and polyoxyethylene sorbitan monolaurate. The agricultural composition may further comprise at least one of a carboxylic acid, a secondary plant metabolite, a plant hormone, a microorganism, a binder, and a diluent, in accordance with the first aspect of the present disclosure herein above.

[0155] The agricultural composition may further comprise at least one of the group including, but not limited to, plant protection products, adjuvants, soil conditioners, biostimulants, seed treatments and fertilizers.

[0156] In a preferred embodiment of the present disclosure, the plant protection product may be an insecticide, pesticide, acaricide, miticide, ovicide, herbicide, fungicide, viricide, nematicide, or nematicide, more preferably, the plant protection product may be a nematicide and / or nematicide. In a preferred embodiment of the present disclosure, the agricultural composition of the present disclosure is provided as a plant protection product and may be an insecticide, pesticide, acaricide, miticide, ovicide, herbicide, fungicide, viricide, nematicide, or nematicide, preferably, the plant protection product may be an insecticide and / or fungicide. More preferably, the plant protection product may be a nematicide and / or nematicide.

[0157] In another preferred embodiment of the present disclosure, the agricultural composition of the present disclosure is provided as an adjuvant, soil conditioner, biostimulant, seed treatment, fertilizer, insect growth regulator, plant regulator and / or elicitor.

[0158] According to a second aspect of the present disclosure, the alkyl lactate and / or derivative thereof according to the first aspect of the present disclosure, the alkyl lactate and / or derivative thereof according to the first aspect of the present disclosure (C2 to C 22 ) an alcohol, a wetting agent according to the first aspect of the present disclosure, a nonionic and / or anionic surfactant according to the first aspect of the present disclosure, and a binder according to the first aspect of the present disclosure.

[0159] The carrier composition may typically be provided as a syrup and / or a gel. The carrier composition typically further comprises a diluent, which is typically water.

[0160] Optionally and / or in addition, the agricultural composition may further comprise an additional diluent, solvent, or co-solvent. The diluent, solvent, or co-solvent is preferably selected from the group comprising alcohols, ethers, esters, diesters, terpenes, glycols, alkyl glycols, glycol ether esters, tall oil, tall oil fatty acid esters, alkylated seed oils, nitrogen compounds, sulfur compounds, halogenated hydrocarbons, and combinations thereof. Preferred solvents or co-solvents are alkyl glycols, glycol ether esters, alkyl lactates, propylene carbonate, tall oil fatty acid esters, alkylated seed oils, such as ethylated or butylated seed oils, and combinations thereof.

[0161] The carrier composition may typically be loaded with an active ingredient and / or a biocontrol agent and / or a fertilizer and / or a biostimulant and / or an elicitor and / or a plant growth regulator and / or an insect repellent to provide a loaded agricultural carrier composition.

[0162] It should be understood that the loaded agricultural carrier composition may contain multiple plant protection products so as to provide, in use, intervention with several divergent modes of action in the treatment and / or control of plant pathogens.

[0163] The active ingredient is typically a plant protection product, which may include at least one of the following groups: insecticides, pesticides, acaricides, miticides, ovicides, herbicides, fungicides, virucides, nematicides, and nematicides, but is not limited to these.

[0164] The biocontrol agent may comprise a microorganism described in the first aspect of the present disclosure and / or a plant hormone described in the first aspect of the present disclosure and / or a carboxylic acid described in the first aspect of the present disclosure and / or a secondary metabolite described in the first aspect of the present disclosure.

[0165] When the carrier composition is loaded with an active ingredient and a biocontrol agent, the applicant provides a multi-layered approach to controlling the pests being addressed. As mentioned above, the multi-layered approach of simultaneously delivering an active ingredient and a biocontrol agent to a plant or soil is fraught with difficulties.

[0166] Applicant was surprised that in preferred embodiments of the loaded agricultural carrier composition in which the biocontrol agent comprises a microorganism and a secondary plant metabolite, the microorganism and plant hormone remained intact and / or intact and / or stable when loaded into the carrier composition. This was particularly surprising when the microorganism is a bacterium and the secondary metabolite is salicylic acid and / or itaconic acid, since salicylic acid and / or itaconic acid are known in the art to destroy and / or harm bacteria.

[0167] Without being limited by theory, applicants believe that (C 10 ~C 22 ) We propose that alkyl lactates provide an effective solvent medium for salicylic acid and / or itaconic acid, while at the same time providing an excellent delivery vehicle for microorganisms without affecting the viability of said microorganisms.

[0168] This unexpected and unique protective behavior exhibited by the unloaded agricultural compositions resulted in an unexpected improvement in longevity over the loaded agricultural compositions, even at room temperature, and was primarily associated with a consistent improvement in viability for all microorganisms and composition embodiments tested in this disclosure when compared to benchmarked products.

[0169] Without being limited to theory, the unloaded agricultural carrier composition delays the germination and extends the lifespan of bacterial spores.

[0170] The unloaded agricultural carrier composition stops and / or prevents and / or delays the spore-forming microorganisms from germinating, and the unloaded agricultural carrier composition coats the spore-forming microorganisms such that the spore-forming microorganisms are dispersed within the unloaded agricultural carrier composition.

[0171] The unloaded agricultural carrier composition is typically provided as a gel that disperses the spore-forming microorganisms therein. When the unloaded agricultural carrier composition is loaded with the spore-forming microorganisms, it provides a loaded agricultural carrier composition. Only after application of the loaded agricultural carrier composition to soil, plants, roots, insects, etc., do the spore-forming microorganisms spread from the gel carrier composition to the surrounding environment, whereupon germination of the microbial spores occurs.

[0172] Furthermore, as shown in the examples below, the unloaded agricultural carrier composition itself exhibits some initial antipathogenic activity. This is advantageous in that upon initial application to the soil, there is a dual effect: first, the initial antipathogenic activity of the unloaded agricultural carrier composition, and second, the (subsequent) antipathogenic activity of the microorganisms (especially after the spores have germinated to an active state). Thus, the loaded agricultural carrier composition provides a two-pronged antipathogenic treatment regime over an extended period of time. This improves efficacy while reducing soil compaction, reducing watering volumes, and allowing for shorter application intervals of plant protection products in a multi-layered approach. This was surprising and unexpected.

[0173] Another unexpected and surprising behavior of the unloaded carrier composition was its ability to improve performance when added to a tank mix with a microorganism. This improved performance occurs whether the microorganism is spore-forming (e.g., Bacillus sp.) or a non-spore-forming species (e.g., Pseudomonas sp.). UCC was added to a tank mix with a prior art product, and it was observed in the following examples that the performance of the prior art product and the loaded agricultural carrier composition was consistently better than that of the prior art product alone.

[0174] In a preferred embodiment of the agricultural carrier composition, (C 10 ~C 22) The alkyl lactate and / or its derivatives may be present in an amount of about 5 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural carrier composition.

[0175] In a preferred embodiment of the agricultural carrier composition, (C2 to C 22 ) The alcohol may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural carrier composition.

[0176] In preferred embodiments of the agricultural carrier composition, the wetting agent may be present in an amount of about 1 wt.% to about 30 wt.% of the total wt.% of the formulated agricultural carrier composition.

[0177] In preferred embodiments of the agricultural carrier composition, the nonionic and / or anionic surfactants may be present in an amount of about 1 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural carrier composition.

[0178] In a preferred exemplary embodiment, the agricultural carrier composition comprises only nonionic surfactants to the exclusion of anionic surfactants, and the nonionic surfactants may be present in an amount of about 1 wt.% to about 50 wt.% of the total wt.% of the formulated agricultural carrier composition.

[0179] In preferred embodiments of the agricultural carrier composition, the binder may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural carrier composition.

[0180] In preferred embodiments of the agricultural carrier composition, the diluent may be present in an amount of about 1 wt.% to about 80 wt.% of the total wt.% of the formulated agricultural carrier composition.

[0181] In a preferred embodiment, the agricultural carrier composition is loaded with a carboxylic acid, which may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated loaded agricultural carrier composition.

[0182] In a preferred embodiment, the agricultural carrier composition is loaded with a plant hormone, which may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated loaded agricultural composition.

[0183] In a preferred embodiment, the agricultural carrier composition is loaded with secondary metabolites, which may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated loaded agricultural composition.

[0184] In a preferred embodiment, the agricultural carrier composition is loaded with microorganisms which may be present in an amount of from about 1 wt.% to about 70 wt.% of the total wt.% of the formulated agricultural composition.

[0185] In preferred embodiments of the agricultural carrier composition (loaded or unloaded), the additive may be present in an amount of about 0.1 wt.% to about 20 wt.% of the total wt.% of the formulated agricultural carrier composition.

[0186] In a preferred exemplary embodiment, the agricultural carrier composition comprises lactyl lauryl lactate, octan-2-ol, glycerin, polyoxyethylene sorbitan monolaurate, and a styrene acrylic polymer. The agricultural carrier composition may further comprise water and / or other co-solvents. The agricultural carrier composition is typically loaded with at least one of a carboxylic acid, a plant hormone, a microorganism, a secondary metabolite, a plant protection product, and / or a biocontrol agent, according to the first and / or second aspects of the present specification.

[0187] The composition according to the first and / or second aspect of the present disclosure may be provided as at least one of the group including, but not limited to, a plant protection product, an adjuvant, a soil conditioner, a biostimulant, a seed treatment, a fertilizer, an insect growth regulator, a plant growth regulator, and an elicitor.

[0188] Applicants are investigating various methods of manufacturing the first and second aspects of the present disclosure. Definitions of certain terms used throughout this disclosure:

[0189] The term "adjuvant" as used herein is a broad term and should be given its original and conventional meaning to those skilled in the art (not limited to a specific or conventional meaning), and refers to, but is not limited to, an agent that modifies the effect of other agents, and more specifically is used to improve the effectiveness of pesticides, such as herbicides, insecticides, fungicides, and other agents.

[0190] The term "stable" as used herein is a broad term and, in conjunction with or in connection with the term "accelerated storage stability," means that the formulation retains similar performance in terms of physicochemical properties after storing samples for 15 days at at least three conditions: room temperature (approximately 20°C); low temperature (0°C or 5°C); high temperature (54°C). Storage stability testing was performed according to CIPAC MT46 method.

[0191] The term "stable" as used herein is a broad term and, in conjunction with or in connection with the term "shelf life," means that the formulation retains similar performance in terms of physicochemical properties and microbial activity after samples are stored for a specified period of time at room temperature (approximately 23°C ± 3°C) in a test also referred to as an actual storage stability test or shelf life test.

[0192] The term "stable" as used herein is a broad term and, in conjunction with or in connection with the term "emulsion," should be construed as its original and conventional meaning to those skilled in the art (without being limited to a specific or conventional meaning), and refers, without limitation, to emulsion stability, i.e., the stability of an emulsion in resisting changes in its properties over time, such that the size of the emulsion droplets does not change significantly over time, more specifically during application to a target mixed with water, and thus should be construed as its original meaning, which is conventional to those skilled in the art. Emulsion stability testing can be performed by the CIPAC MT 36 method.

[0193] The term "solvent" or "co-solvent" as used herein is a broad term and should be construed as giving its original and conventional meaning to those skilled in the art (without being limited to a specific or conventional meaning), and refers to a compound that may be polar or non-polar, straight or branched chain, cyclic or aliphatic, aprotic or amphoteric, and has some characteristic of solvency for other compounds or means, including, but not limited to, alcohols, acids, amines, ethers, esters, diesters, ketones, acetates, terpenes, sulfoxides, phenols, glycols, alkyl glycols, glycol ether esters, paraffins, hydrocarbons, heterocyclic, aromatic, naphthenic, nitrogen compounds, sulfur compounds, halogenated hydrocarbons, mixtures or combinations of solvents, among others.

[0194] Whenever a group is described as being "optionally substituted," the group can be unsubstituted or substituted with one or more of the indicated substituents. Similarly, when a group is described as being "unsubstituted or substituted," if substituted, the substituents can be selected from one or more of the indicated substituents. When no substituents are indicated, the indicated "optionally substituted" or "substituted" group can be any of alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, cycloalkynyl, aryl, heteroaryl, heteroalicyclyl, aralkyl, heteroaralkyl, (heteroalicyclyl)alkyl, hydroxy, protected hydroxyl, alkoxy, aryloxy, acyl, mercapto, alkylthio, arylthiol, cyano, halogen, thiocarbonyl, O-carbamyl, N-carbamyl, O-thiocarbamyl, N- It means that each may be substituted with one or more groups independently selected from thiocarbamyl, C-amido, N-amido, S-sulfonamido, N-sulfonamido, C-carboxy, protected C-carboxy, O-carboxy, isocyanato, thiocyanato, isothiocyanato, nitro, silyl, sulfenyl, sulfinyl, sulfonyl, haloalkyl, haloalkoxy, trihalomethanesulfonyl, trihalomethanesulfonamido, amino, monosubstituted amino and disubstituted amino groups, and protected derivatives thereof.

[0195] The term "alkyl," as used herein, is a broad term and should be construed as conferring its original and customary meaning to those of ordinary skill in the art (and is not intended to be limited to a specific or customary meaning), and refers to a straight or branched chain, acyclic or cyclic, unsaturated or saturated aliphatic hydrocarbon containing, but not limited to, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36 or more carbon atoms; the term "lower alkyl" has the same meaning as alkyl but containing 1, 2, 3, 4, 5, or 6 carbon atoms. Representative straight-chain saturated alkyls include methyl, ethyl, n-propyl, n-butyl, n-pentyl, n-hexyl, and the like; branched-chain saturated alkyls include isopropyl, sec-butyl, isobutyl, tert-butyl, isopentyl, and the like. Unsaturated alkyls contain at least one double or triple bond between adjacent carbon atoms (referred to as "alkenyl" or "alkynyl," respectively). Representative straight-chain and branched-chain alkenyls include ethylenyl, propylenyl, 1-butenyl, 2-butenyl, isobutylenyl, 1-pentenyl, 2-pentenyl, 3-methyl-1-butenyl, 2-methyl-2-butenyl, 2,3-dimethyl-2-butenyl, and the like; representative straight-chain and branched-chain alkynyls include acetylenyl, propynyl, 1-butynyl, 2-butynyl, 1-pentynyl, 2-pentynyl, 3-methyl-1 butynyl, and the like. Exemplary alkyl groups include, but are not limited to, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tertiary butyl, pentyl, hexyl, heptyl, octyl, nonyl, decyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, octadecyl, nonadecyl, eicosyl, heneicosyl, docosyl, tricosyl, tetracosyl, pentacosyl, hexacosyl, heptacosyl, octacosyl, nonacosyl, triacontyl, henateriacontyl, dotriacontyl, tritriacontyl, tetratriacontyl, pentatriacontanyl, and hexatriacontanoic acid. The alkyl group may be substituted or unsubstituted.

[0196] The term "alkoxy," as used herein, is a broad term and should be construed as giving its original and conventional meaning to those of ordinary skill in the art (and is not limited to a specific or conventional meaning), and refers to an alkyl moiety attached through an oxygen bridge (i.e., -O-alkyl), such as, but not limited to, methoxy, ethoxy, and the like.

[0197] The term "alcohol," as used herein, is a broad term and should be construed as giving its original and conventional meaning to those of ordinary skill in the art (without being limited to a specific or conventional meaning), and refers to, without limitation, any compound described herein that incorporates one or more hydroxy groups or that is substituted or functionalized to include one or more hydroxy groups.

[0198] The term "ester," as used herein, is a broad term and should be construed as giving its original and conventional meaning to those of ordinary skill in the art (without being limited to a specific or conventional meaning), and refers to any compound described herein that incorporates, or is substituted or functionalized to include, one or more ester groups, e.g., monoesters, diesters, triesters, or polyesters, without limitation. Esters include, but are not limited to, fatty acid esters.

[0199] The term "glycol," as used herein, is a broad term and should be construed as giving its original and conventional meaning to those of ordinary skill in the art (without being limited to a specific or conventional meaning), and may include diols, e.g., polyalkylene glycols, e.g., polyethylene glycol polymers having the formula H(OCHCH)OH (n greater than 3), polypropylene glycol, or glycols incorporating monomers containing long hydrocarbon chains. [Example]

[0200] Non-limiting examples The examples of the present disclosure should not be construed as limiting, as applicants envision extending the scope of agricultural uses.

[0201] The compositions according to the first and second aspects of the present disclosure have been tested as plant protection products, preferably as nematicides and / or nematicides. Preferred embodiments include biocontrol agents.

[0202] [Table 1-1]

[0203] [Table 1-2]

[0204] [Table 2-1]

[0205] [Table 2-2]

[0206] [Table 3]

[0207] Methods for preparing loaded agricultural carrier compositions according to the present disclosure For illustrative purposes, methods for preparing the loaded agricultural carrier compositions (LCCs) used in the non-limiting examples are outlined below.

[0208] The preparation and use of loaded agricultural carrier compositions (LCCs) are provided. Typically, loaded agricultural carrier compositions are prepared as concentrates containing at least an antipathogenic agricultural compound and / or an antipathogenic agricultural microorganism and / or an antipathogenic agricultural mixture of microorganisms dissolved or dispersed in an unloaded agricultural carrier (UCC). The antipathogenic loaded agricultural carrier composition is stable and can be stored for at least one year at room temperature (approximately 20°C) or even under refrigerated conditions (approximately 5°C), and can be diluted before use. Alternatively, the antipathogenic agricultural compound and the unloaded agricultural carrier can be mixed and then diluted. The loaded agricultural carrier composition is typically diluted with water or other means to provide a stable tank mix of the diluted agricultural composition prior to use or application to or adjacent to an agricultural crop or soil of an agricultural crop to control pathogen populations and / or control and / or treat diseases associated with the pathogens. The present disclosure extends to the application of agricultural compositions to or adjacent to soil, substrates, plants, plant parts, animals, buildings, equipment, etc. The loaded agricultural carrier compositions according to the present disclosure are stable before and during use.

[0209] Antipathogenically loaded agricultural carrier compositions according to the present disclosure are typically in the form of a liquid and / or syrup and / or gel having active ingredients and / or biocontrol agents dissolved or dispersed in the agricultural carrier, and are stable as concentrates and stable in tank mixes. Antipathogenically loaded agricultural carrier compositions are provided as compositions containing two or more chemical compounds. Concentrated, stable antipathogenically loaded agricultural carrier compositions include (C2 to C6) in amounts of 5.0 to 50.0 wt.%. 26 ) alkyl lactate and / or its derivatives; (C2 to C6) in an amount of 0.1 to 20.0 wt.% 22 ) alcohol; wetting agent in an amount of 1.0 to 30.0 wt.%; nonionic and / or anionic surfactant in an amount of 1.0 to 50.0 wt.% ;0 Binder in an amount of 1 to 20.0 wt.%; Diluent in an amount of 1.0 to 80.0 wt.% (water), preferably water; and one or more biocontrol agents, preferably one or more species of bacteria or fungi, in an amount of 1.0 to 70.0 wt.%, and the anti-pathogenic loaded agricultural carrier composition is stable in concentrate form and has a shelf life at room temperature (approximately 20°C) of at least one year.

[0210] The anti-pathogenic agricultural compounds and / or anti-pathogenic agricultural microorganisms and / or anti-pathogenic agricultural mixtures of microorganisms referred to herein may be insecticides, pesticides, acaricides, miticides, ovicides, herbicides, fungicides, virucides, nematicides, nematicides, insect growth regulators.

[0211] The unloaded agricultural carrier (UCC) may alternatively and / or additionally be loaded with plant growth regulators, elicitors, biostimulants and / or fertilizers.

[0212] Applicants were surprised by the long shelf life of the compositions according to the present disclosure. Furthermore, the compositions did not exhibit phase separation and remained stable for extended periods of time.

[0213] It should be understood that the antipathogenic agricultural composition and the unloaded agricultural carrier composition (UCC) can be mixed and then diluted. The antipathogenic agricultural composition can be at least an antipathogenic agricultural compound / composition and / or an antipathogenic agricultural microorganism and / or an antipathogenic agricultural mixture of microorganisms. In a preferred embodiment, the unloaded agricultural carrier composition (UCC) is first added to a tank mix resulting in a stable solution of the unloaded agricultural carrier, and in a second step, the antipathogenic agricultural composition (preferably a microorganism) is added to the agricultural carrier solution resulting in the antipathogenic agricultural composition dispersed or diluted in the agricultural carrier solution. This mixed, diluted or dispersed antipathogenic agricultural composition is stable and capable of controlling pathogen populations and / or controlling and / or treating diseases associated with said pathogens upon application to or adjacent to agricultural crops or soil of agricultural crops. The present disclosure extends to application of agricultural compositions to or adjacent to soil, substrates, plants, plant parts, animals, buildings, equipment, etc. Unloaded agricultural carrier compositions (UCCs) according to the present disclosure are stable before and during use.

[0214] The unloaded agricultural carrier composition (UCC) is provided as a liquid and / or syrup and / or gel composition containing two or more chemical compounds. The concentrated, stable unloaded agricultural carrier composition (UCC) comprises 5.0 to 50.0 wt.% of (C2 to C3). 26 ) alkyl lactyl lactate and / or its derivatives; (C2-C6) in an amount of 0.1-20.0 wt.% 22 ) alcohol; a wetting agent in an amount of 1.0 to 30.0 wt.%; a nonionic and / or anionic surfactant in an amount of 1.0 to 50.0 wt.%, preferably one nonionic surfactant. ;0 Binder in an amount of 1 to 20.0 wt.%; and diluent in an amount of 1.0 to 80.0 wt.%. (water) , preferably may contain water and / or other co-solvents, and the unloaded agricultural carrier composition (UCC) is stable and has a shelf life of at least 2 years at room temperature (approximately 20° C.).

[0215] The anti-pathogenic agricultural compounds and / or anti-pathogenic agricultural microorganisms and / or anti-pathogenic agricultural mixtures of microorganisms referred to herein may be insecticides, pesticides, acaricides, miticides, ovicides, herbicides, fungicides, virucides, nematicides, nematicides, insect growth regulators.

[0216] Testing of a Loaded Agricultural Carrier Composition (OR-501) According to the Present Disclosure as a Nematicide and / or Nematicide Applicants tested a series of compositions according to the present disclosure, including an unloaded carrier composition (UCC), a preferred embodiment of a loaded carrier composition (pLCC, also referred to as OR-501), OR-501 further loaded with other active agents and / or biocontrol agents, a composition with a bacterial biocontrol agent alone, a commercially available composition, water, and a control. All compositions were tested for activity in killing and / or immobilizing nematodes.

[0217] In broad terms, compositions according to the present disclosure have demonstrated nematicidal and / or nematicidal properties superior to those of the chemical standard, oxamyl, which has been systematically phased out due to potentially harmful uses in the environment. There is a need for more environmentally friendly nematicides that exhibit similar or better efficacy than conventional chemical standards such as oxamyl.

[0218] In particular, Applicant was surprised that in a preferred embodiment of the loaded agricultural carrier composition (also referred to as OR-501) in which the biocontrol agent comprises a microorganism and a plant hormone, the microorganism and plant hormone remained intact and / or intact and / or stable when loaded into the carrier composition. This was particularly surprising when the microorganism is a bacterium and the plant hormone is salicylic acid, since salicylic acid is known in the art to destroy and / or harm bacteria.

[0219] Example 1 Nematicide Laboratory Testing - Various compositions were prepared and tested in vitro as nematicides and / or nematicides as described in Table 2.

[0220] The unloaded carrier composition (UCC) is a mixture of alkyl lactates and / or derivatives (e.g., alkyl lactyl lactates), (C2-C 22 ) alcohol (octan-2-ol), wetting agent (glycerin), non-ionic surfactant (polyoxyethylene sorbitan monolaurate), and binder (styrene acrylic polymer) and water It was made up of:

[0221] The preferred loading carrier composition (pLCC, also called OR-501) is (C 10 ~C 22 ) Alkyl lactate and / or derivatives (lactyl lauryl lactate), C2-C 22 Alcohol (octan-2-ol), humectant (glycerin), non-ionic surfactant (polyoxyethylene sorbitan monolaurate) , conclusion Mixture (styrene acrylic polymer), water, It consisted of microorganisms (Bacillus amyloliquefaciens spp., especially CM5; ATCC PTA-12138) as well as secondary metabolites (salicylic acid).

[0222] [Table 4]

[0223] Experimental setup and bioassay methodology: The bioassay was designed to determine the efficacy of the tested formulations and included the following steps: 1. Extract nematodes from carrot discs using mesh extraction method; 2. Count the extracted nematodes in 100 μL water samples; 3. Preferably, the number of nematodes in such a sample is between 40 and 80 nematodes; 4. Determine potency on ELISA plates; 5. Prepare stock solutions that are at least 10 times more diluted than the primary formulation for all treatments; 6. For treatments tested at 5% or 1.5%, 50 μL or 15 μL aliquots of the corresponding stock solution were introduced into the wells, respectively. The volume was filled up with 50 μL of nematode extract, and an additional 35 μL of distilled water was introduced to reach a total volume of 100 μL, except for the treatment tested at 1.5%. The contents of the wells were mixed thoroughly with a pipette to ensure proper distribution of both nematodes and treatment components; 7. Each treatment was replicated at least six times. The flasks containing the nematode colonies were mixed by manual shaking each time before introducing the nematodes into the wells. This ensured some uniformity in the number of nematodes and avoided the nematodes settling to the bottom of the flask; 8. Keep the entire ELISA plate in the dark for 24 hours after introducing the treatment; 9. Nematode mortality was assessed under a stereoscope 24 hours after treatment. Moving nematodes were considered alive. Non-moving nematodes were poked with a fine brush and were considered alive if they moved slightly in response to the poking. If they did not move, they were considered dead. The only validity criterion was that nematode mortality in the negative control must not exceed 10%.

[0224] Statistical analysis: Raw mortality data were analyzed using RStudio (version 1.4.1717). Data sets were subjected to a Shapiro-Wilk test for normality (α = 0.05). Data were not normally distributed, therefore, a Kruskal-Wallis test was applied. Where significant, a Wilcoxon rank sum t-test was performed for pairwise comparisons between treatment groups.

[0225] result [Table 5-1]

[0226] [Table 5-2]

[0227] [Table 5-3]

[0228] [Table 5-4]

[0229] Figure 1 shows the nematicidal efficacy of selected bacteria when applied alone or mixed with an unloaded carrier composition (UCC). Nematode mortality is significantly increased when Bacillus subtilis, Bacillus amyloliquefaciens, and Pseudomonas fluorescens are applied in mixtures with the unloaded carrier composition. The study also showed that OR-501 / pLCC exhibited the highest nematicidal efficacy of the exemplified treatments, interestingly resulting in significantly higher mortality compared to the synthetic standard, oxamyl.

[0230] Figure 1 shows box plots with the interquartile range including the horizontal line as the median. Whiskers indicate SEM. Points represent outliers. Asterisks indicate statistically significant differences between treatments.

[0231] Figure 2 shows box plots with the interquartile range including the horizontal line as the median. Whiskers indicate SEM. Points represent outliers. Asterisks indicate statistically significant differences between treatments.

[0232] From Figure 2, it can be seen that including plant secondary metabolites in the formulation improved the overall efficacy when compared to UCC. Furthermore, the addition of maltodextrin to UCC did not have any significant effect on nematode mortality.

[0233] A microbial nematicide from Koppert® (brand name Veraneio® in Brazil) was also tested to compare efficacy with pLLC. The results are shown in Figure 3. Figure 3 shows a box plot showing the interquartile range with the horizontal line as the median. The whiskers indicate the SEM. The points represent outliers. The asterisks indicate statistically significant differences between treatments.

[0234] pLLC clearly performed significantly better than the competitor's product, achieving nearly 90% nematode mortality compared to Koppert® microbial nematicide at 5.6%.

[0235] The unloaded agricultural carrier composition (UCC) itself exhibits some initial antipathogenic activity (see Figure 2). This is advantageous in that upon initial application to the soil, there is a dual effect: first, the initial antipathogenic activity of the unloaded agricultural carrier composition, and second, the (subsequent) antipathogenic activity of the microorganisms (especially after the spores have germinated to an active state). Thus, the loaded agricultural carrier composition provides a two-pronged antipathogenic treatment regime over an extended period of time. This improves efficacy while reducing soil compaction, reducing watering volumes, and allowing for shorter application intervals of plant protection products within a multi-layered approach. This was surprising and unexpected.

[0236] Complementary nematicidal laboratory tests The purpose of this test was to evaluate the nematicidal effect of the composition prepared by this application (C2 to C 26 ) to better understand the effects of alkyl lactate derivatives. All tested compositions are summarized in Table 4.

[0237] (I C 10 ~C 22 ) alkyl lactates [lactyl lauryl lactate (UCCa), lauryl lactate (UCCb), cetyl lactate (UCCc) and a mixture of lauryl lactate, myristyl lactate and cetyl lactate (UCCd)]; (ii) (C2-C 22 Four unloaded carrier compositions (UCCa, UCCb, UCCc, UCCd) were prepared containing: (i) an alcohol (octan-2-ol); (ii) a humectant (glycerin); (iii) a nonionic surfactant (polyoxyethylene sorbitan monolaurate); (v) a binder (styrene acrylic polymer), and (vi) a secondary metabolite (salicylic acid).

[0238] (I C 10 ~C22 ) Alkyl lactate (lactyl lauryl lactate); (ii) (C2-C 22 A fifth unloaded carrier composition (UCCe) was prepared, comprising: (i) an alcohol (octan-2-ol); (ii) a humectant (glycerin); (iii) a nonionic surfactant (polyoxyethylene sorbitan monolaurate); (v) a binder (styrene acrylic polymer); and (vi) a secondary metabolite (itaconic acid).

[0239] [Table 6]

[0240] Experimental setup and bioassay methodology The nematicide efficacy protocol consists of the following steps: 1- Extraction of nematodes from carrot discs using mesh extraction method. 2- Count the extracted nematodes in a 100 μL water sample. 3- The number of nematodes in such a sample is preferably between 60 and 80 nematodes. 4- Potency was tested in ELISA plates. 5- The entire ELISA plate was kept in dark conditions for 24 hours after the introduction of treatments. 6- The mortality of nematodes was assessed under a stereoscope 24 hours after treatment. Moving nematodes were considered alive. Non-moving nematodes were poked with a fine brush and slight movement in response to the poking was considered alive. No movement was considered dead. 7- The only validity criterion was that nematode mortality in untreated controls must not exceed 10%.

[0241] result Figure 5 shows the nematicidal efficacy of the various tested compositions. Mortality of Pratylenchus penetrans peaked at 73.9% in response to B-017-03, which contained UCCb formulated with lauryl lactate. B-017-04, which contained UCCc formulated with cetyl lactate, and B-017-05, which contained UCCd (formulated with a mixture of lauryl, cetyl, and myristyl lactates), caused mortality of 60.1% and 58.5%, respectively. Reducing the concentration of B-017-05 to 1% and 0.5% resulted in significantly lower nematode mortality, characterizing a dose-response effect, as shown in Figure 5.

[0242] B-017-06 contains a bacterial agent, Bacillus subtilis BS03 (GAT), which is different from the microorganism (Bacillus amyloliquefaciens) used in the other compositions. The efficacy of B-017-06 (48.9%) was significantly lower than all B. amyloliquefaciens compositions. Other strains and species of Bacillus subtilis will be included in future nematicidal testing.

[0243] When salicylic acid was replaced with itaconic acid, efficacy was compromised in nematicide control, with nematode mortality for B-017-07 at 23.4%. Even though 23.4% control may be considered promising considering the dosage used, it is clear that reducing the dosage from 5% to 2% affected the nematicide control of composition B-017-07. Another set of tests is underway, including similar dosages of itaconic acid and salicylic acid, to evaluate both metabolites at the same percentages and dosages.

[0244] The test is considered valid as the mortality of nematodes with untreated control did not exceed 10%.

[0245] Conclusion - All tested (C 10 ~C 22) The alkyl lactates exhibit unique interactions with other components to form very well-structured gels that retain viable microorganisms even at room temperature, which is surprising and shows promising ability to improve the shelf life and performance of agronomic compositions, such as insecticides, miticides, acaricides, ovicides, herbicides, fungicides, virucides, nematicides, nematicides, insect growth regulators, plant growth regulators, elicitors or biostimulants, when the agronomic compositions contain biological species or alone as an adjuvant.

[0246] Complementary Fungicide Laboratory Testing Screening of fungicides for pest efficacy Studies were conducted to evaluate the efficacy of compositions of the present disclosure as fungicides by testing their ability to inhibit the growth of selected fungi, namely Botrytis cinerea, Alternaria alternata, Monolinia fructicula, and Fusarium graminearum. In a first set of tests, efficacy was evaluated using different types of alkyl lactates, as well as fungicides of different compositions made according to the present disclosure, using comparative prior art products and negative controls. Different fungi were selected based on their prevalence and ability to induce disease in crops.

[0247] Study description: Different dilutions of different variants of the compositions according to the present disclosure (specifically UCCa and UCCb loaded with microbial agents) were prepared, inoculated into appropriate culture media (potato dextrose agar) and exposed to different fungi in their exponential growth phase in sterile Petri dishes. After an incubation period, the effect of each substance / concentration combination on the growth of the fungi was evaluated.

[0248] Equipment: Scale - Compositions, culture media and required dilutions were prepared using a calibrated scale, trade name Sartorius, model Quintix 3102-1S.

[0249] Autoclave - All culture media before use, and the biological waste generated, were sterilized in an autoclave, trade name AJCosta, model UNICLVE 88.

[0250] Biological safety cabinet - All studies requiring sterile conditions were performed in a biological safety cabinet, trade name Euroclone, model Safemate EZ 1.2.

[0251] Incubator - All plates were incubated at 25°C in an incubator, Raypa brand, model DOD-90.

[0252] Samples tested: Different compositions made according to the present disclosure using different types of alkyl lactates, prior art products and negative controls, as set forth in the table below.

[0253] [Table 7]

[0254] The above compositions were diluted with water to 0.5% (w / w), 1% (w / w) and 5% (w / w).

[0255] Discs were impregnated with each dilution of each composition and inserted in triplicate into Petri dishes containing potato dextrose agar (PDA).

[0256] PDA was the medium of choice, a rich culture medium that promoted overall growth of the fungus so that the fungus did not experience any other limitations in growth other than exposure to the compositions in the test.

[0257] Once dry, a cube of each of the fungi selected for this study (Botrytis cinerea, Alternaria alternata, Monolinia fructicula, and Fusarium graminearum) in their exponential growth phase was inserted into the center of the plate. The plate was incubated at 25°C for 7 days.

[0258] After the incubation period, the diameter of the growth inhibition was measured per plate in millimeters.

[0259] result The results obtained for diameter of growth inhibition in millimeters of Alternaria alternata after incubation are given in Table 6 below.

[0260] [Table 8]

[0261] The results obtained for diameter of growth inhibition in millimeters of Botrytis cinerea after incubation are given in Table 7 below.

[0262] [Table 9]

[0263] The results obtained for diameter of growth inhibition in millimeters of Monolinia fructicula after incubation are given in Table 8 below.

[0264] [Table 10] The results obtained for diameter of growth inhibition in millimeters of Fusarium graminearum after incubation are given in Table 9 below.

[0265] [Table 11]

[0266] Interpretation of results The negative control (composition identified as 0) showed no growth inhibition for all fungi tested, as there was no impairment to fungal growth after incubation.

[0267] For all fungi tested, all compositions exhibited significant inhibition of fungal growth when compared to the negative control.

[0268] Table 10 presents the percentage efficacy of each composition relative to a registered biological product (composition identified as 4) derived from a prior art product based on Bacillus subtilis. Dosage grades were applied to each fungus in the evaluation, starting with a low dosage of 0.5% up to a higher concentration of 5% for each composition.

[0269] The mean values ​​obtained for growth inhibition relative to the standard standard of the higher tested dosage (at 5% w / w) of the prior art were inferred as a relative control (efficacy) of 100%, and the means of all other compositions were considered using a reference percentage of 100% from the standard standard applied at 5% w / w.

[0270] The average results for the remaining compositions tested at different dosages and species are shown in Table 10.

[0271] [Table 12]

[0272] Consideration Under the conditions used in this experiment, all tested compositions (1-4), except for the negative control, showed similar efficacy in inhibiting the growth of the fungi Alternaria alternata, Botrytis cinerea, Fusarium graminearum, and Monolinia fructicula. Also, even though low dosages, ten times lower than the high dosages, were used, it was difficult to establish a clear dose response against the tested fungi.

[0273] Despite the different species used in compositions 1 and 2 based on Bacillus amyloliquefaciens and the different alkyl lactates used in each of the three compositions, the screening tests clearly showed that compositions 1 and 2 based on Bacillus amyloliquefaciens performed slightly better or equally well to the commercial fungicides based on Bacillus subtilis.

[0274] For the control of Monolinia fructiculata, compositions 3 and 4 are relatively more effective than compositions 1 and 2. Bacillus subtilis appears to be more effective than Bacillus amyloliquefaciens in controlling Monolinia fructiculata.

[0275] Conclusion: Under the conditions used in this in-vitro screening test, at all tested concentrations, all compositions exhibited inhibition of fungal growth when compared to the negative control.

[0276] Against the fungi Alternaria alternata, Botrytis cinerea and Fusarium graminearum, the results observed were statistically similar for all four compositions tested, with composition 1 performing slightly better.

[0277] Against the fungus Monolinia fructicula, the observed results may suggest that Bacillus subtilis controls Monolinia fructicula better than Bacillus amyloliquefaciens. Compositions 3 and 4 performed statistically better than Compositions 1 and 2. Composition 3 performed slightly better than Composition 4 in controlling Monolinia fructicula.

[0278] Complementary insecticide laboratory testing Evaluation of the contact toxicity of some Bacillus amyloliquefaciens compositions against the red spider mite, Tetranychus urticae (order Trombidiformes)

[0279] Location: Strand (South Africa) Pests: Red spider mite, Tetranychus urticae Life stage: Adult female Application method: Potter spray tower Number of applications: 1 time Objective: To test the efficacy of several Bacillus amyloliquefaciens compositions as contact insecticides.

[0280] [Table 13]

[0281] Test animals and maintenance Adult females of T. urticae (order Trombidiformes: family Tetranychidae) were obtained from a laboratory colony maintained at Oro Agri SA, Strand, South Africa. The colony was grown on runner beans and maintained at a constant temperature of 25°C and a 12:12 L:D photoperiod.

[0282] Laboratory bioassays Petri dishes with modified lids were used to contain the mites during application and for the duration of the test. The lids were modified to include square mesh to reduce the relative humidity in the Petri dishes. One cotton pad was placed in each Petri dish and moistened with 10 mL of water. Leaf discs (2.2 cm in diameter) were cut from bean plants using a cork borer and placed on the moist cotton pads to moisten them. Two leaf discs were placed on each cotton pad to serve as a food source for the mites. The discs were placed with the underside facing up, as mites feed primarily on the underside of the leaves. Five adult female mites were placed on each leaf disc, and five Petri dishes were used per treatment (i.e., 50 mites per treatment). After treatment application, individuals were left in each Petri dish for evaluation of mortality and disease rates over the test period.

[0283] [Table 14]

[0284] Treatment application A Potter spray tower (Potter Precision Laboratory Spray Tower, Burkard Scientific) was used for all treatment applications. The Potter tower was calibrated with 5 mL of solution, equivalent to 415 L / ha (see ZA 2015 Potter Tower Spray Volume). To apply treatments, Petri dishes containing mites were placed on the Potter tower platform and sprayed once with 5 mL of the desired treatment (at 0.6 bar pressure). After application, Petri dishes were stored in a temperature-controlled room at a constant temperature of 25°C.

[0285] Mortality and disease rate assessment Mortality and disease rates were assessed 24 and 48 hours after application. Mites were considered dead if they had not moved their legs within 10 seconds of being poked with a fine paintbrush. Disease rate was defined as when individuals were found to be no longer healthy but not dead (i.e., leg movements were still visible).

[0286] Figure 6 shows the percentage of mites killed 24 hours after treatment application. Statistical analysis – Mortality 24 hours after treatment application The statistical package PAST was used for all statistical analyses.

[0287] A Shapiro-Wilk test was performed and showed that the data were not normally distributed (p<0.05). Therefore, rather than analyzing the data using ANOVA, a Kruskal-Wallis test was performed, which showed that there was a significant difference between the treatments (p<0.0001).

[0288] Post-hoc Mann-Whitney comparisons were then performed to distinguish which treatments were significantly different from each other. The tests showed that all treatments were significantly better (i.e., produced significantly higher mortality) than the control group (see Table 13 and Figure 6). The following treatments were also significantly better than the chemical standard, producing higher mortality: B-017-003, B-017-004, and B-017-005 (see Table 13 and Figure 6).

[0289] [Table 15]

[0290] Figure 7 shows the percentage of mites killed 48 hours after treatment application. Statistical analysis - Mortality 48 hours after treatment application The statistical package PAST was used for all statistical analyses.

[0291] A Shapiro-Wilk test was performed and showed that the data were not normally distributed (p<0.05). Therefore, rather than analyzing the data using ANOVA, a Kruskal-Wallis test was performed, which showed that there was a significant difference between the treatments (p<0.001).

[0292] Post-hoc Mann-Whitney comparisons were then performed to distinguish which treatments were significantly different from each other. The tests showed that all treatments were significantly better than the control group (i.e., produced significantly higher mortality rates) ( Table 14 (See

[0293] [Table 16]

[0294] Discussion and Conclusions The results showed that all four different compositions tested for efficacy against red spider mites (see Table 14: B-017-001; B-017-003; B-017-004; B-017-005) resulted in significantly higher mortality when compared to the control group 24 and 48 hours after treatment application (see Tables 13 and 14 and Figures 6 and 7).

[0295] It can be concluded that all four compositions tested (B-017-001, B-017-003, B-017-004, and B-017-005) have significant efficacy against mites when applied as contact insecticides / acaricides. All four compositions were effective against red spider mites, resulting in significantly higher mortality rates compared to the control.

[0296] The use of the agricultural carrier composition of the present disclosure with other species of bacteria to provide a loaded agricultural carrier composition that acts as an insecticide and / or acaricide is warranted. The use of entomopathogenic fungi in different gel bases (UCC and / or UCCa and / or UCCb and / or UCCc and / or UCCd and / or UCCe) tailored to improve efficacy will be tested in a series of tests on various insects. The pests used as model organisms for efficacy screening will also be used at the Oro Agri facility in South Africa and Portugal. The selected pests will be at least a) Tetranychus urticae (order Trombidiformes) - red spider mite; b) Planococcus ficus - grape mealybug; and c) Bathycoelia distincta (order Hemiptera) - two-spotted stinkbug. For each target, at least one test is performed against each of the entomopathogenic fungi: Beauvaria bassiana and Metarhizium anisopilae. Chemical and biological standards are used as efficacy comparisons and controls.

[0297] Example 2 Nematicide Field Testing The pot trials were carried out under controlled conditions in a growth chamber at the Oro Agri South Africa facility in Strand, South Africa. All growth chamber trials were equipped with artificial lighting, air conditioning and irrigation systems suitable for plant growth.

[0298] [Table 17]

[0299] material and method Description of experimental design and test layout The test consisted of six treatments with five replicates each. All pots were filled with the same soil mixture and planted with tomato plants, one plant per pot. Nematodes for inoculating the soil were obtained from ARC in Stellenbosch. The nematodes were Meloidogyne javanica and were applied as a drench (100 mL) to each pot around the base of the plants at 3555 eggs / J2 per pot. Product treatments were also applied four days later as a soil drench treatment.

[0300] Pruning tomatoes Plants are pruned according to laboratory method M059. Tomato plants are pruned when the plants are at least 15 cm tall. Pruning shears are used to cut the main stem 1 cm above the second or third true leaf of each plant to stimulate the growth of lateral buds.

[0301] Microbial inoculation Since the products applied in this test as treatments are primarily nematicides, the soil needs to have a microbial population to simulate microbe-nematode interactions.

[0302] Therefore, a microbial inoculum application was applied to all treatments to simulate this effect. The microbial inoculum was a consortium of 21 microbial species, including some species with multiple strains, making a total of 31 strains. This is a commercially available product with a field application rate of 2 L / ha. The microbial inoculum was applied 4 days before inoculation with nematodes.

[0303] Nematode inoculation Nematode inoculation was performed 4 days before product treatment at 3555 eggs / J2 per pot. This is a slightly lower inoculation rate than desired due to the suboptimal nematode population. Three holes, 5 mm in diameter and 3.5 cm deep, were made around the plants and 5 mL of inoculation solution was applied. The holes were immediately sealed. The soil was thoroughly moistened before inoculation.

[0304] Measured parameters [Table 18]

[0305] [Table 19]

[0306] result Figure 4, Root Extraction Counts - Number of eggs and second stage juveniles per gram of root

[0307] Discussion and Conclusions The results for root extraction are shown in Figure 4. The data show that OR-501x and OR-501y at 0.1% were significantly lower than the untreated (+); nematode infestation in the roots was significantly lower as a result of the treatment. OR-501x and OR-501y at the low rate of 0.01% were less effective than the 0.1% concentration. All other treatments were numerically lower than the untreated. (-) Very low levels of contamination were observed in the untreated.

[0308] These results are encouraging, as they represent a significant reduction in nematode numbers, considering that the product is only an antagonist and not a direct nematicide. More trials are needed to establish efficacy and to experiment with ideal application rates.

[0309] Examples 1 and 2 demonstrate compositions according to the present disclosure that are effective nematicides, insecticides, and fungicides. Applicant envisions conducting further detailed experiments to demonstrate that the compositions are generally effective plant protection products.

[0310] Applicant proposes that the agricultural composition and / or agricultural carrier composition (loaded / unloaded) ameliorate at least one disadvantage known in the prior art.

[0311] Example 3 Direct Method for Bacterial Quantification - Shelf Life Test equipment Scale - Compositions, culture media, and necessary dilutions should be prepared using a calibrated scale. The trade name for the one used in Palmela facilities is Sartorius, Model Quintix 3102-1S.

[0312] Autoclave - All culture media and generated biological waste should be sterilized in an autoclave before use. The trade name for the one used at the Palmela facilities is AJCosta, model UNICLVE 88.

[0313] Biological Safety Cabinets - All research requiring sterile conditions should be performed in a biological safety cabinet. The trade name for the one used at the Palmela facilities is AJCosta EuroClone, model Safemate EZ 1.2.

[0314] Incubator - All plates should be incubated at the appropriate temperature based on the microorganism of interest for quantification. As a general rule, 35°C is the temperature of choice for the most common bacteria. The trade name for the incubator used at the Palmela facilities is Raypa, model DOD-90.

[0315] method The direct method of bacterial quantification by plating a predetermined amount of sample has the advantage of its high sensitivity. The method is based on the principle that every viable microorganism will reproduce and produce a visible colony. Each single bacterial cell in the sample, once infested, is considered to give rise to one visible colony.

[0316] Serial dilutions of the sample of interest should be performed based on the expected CFU of the original sample to have 30-300 colonies per plate.

[0317] 2×10 9For samples with theoretical values ​​of CFU / mL, serial dilutions should be performed up to 10-7, and 100 μL of the relevant dilution should be spread onto Petri dishes containing a non-selective agar medium such as tryptic soy agar (TSA).

[0318] At least two independent serial dilutions should be performed. Each independent preparation should be spread onto Petri dishes of each relevant dilution in triplicate.

[0319] Based on the expected number of CFU / mL of the original undiluted sample, the relevant dilutions (triplicates) to be spread on Petri dishes are ideally those that will yield between 30 and 300 colonies per plate, as well as those above and below that to allow for variability in the actual number relative to the theoretical one.

[0320] 2×10 9 Considering the CFU / mL and the fact that 100 μL of the relevant dilution is actually spread onto Petri dishes, the ideal dilution to spread onto Petri dishes is 10-6, which would theoretically result in 200 CFU / plate after the incubation period. The other two dilutions to spread onto Petri dishes should be 100 μL of dilution 10-5 (triplicate) and 100 μL of dilution 10-7.

[0321] After plating, the Petri dishes should be incubated for a more suitable incubation period of 24 hours and the number of colonies on each plate should be counted.

[0322] Sample Identification: [Table 20]

[0323] Shelf-life testing is ongoing in several of the company's laboratories in Palmela (Portugal), Valencia (Spain), Strand (South Africa), São Paulo (Brazil) and Fresno (USA), including third-party laboratories, using alkyl lactate-based gels as carriers for biologics and other products.

[0324] result [Table 21]

[0325] comment Batch 50120210709 is already 19 months old and as can be observed from the results, the bacterial CFU / mL remained stable over time at room temperature (23°C ± 3°C). Other batches, although more recent, also show stable bacterial or colony counts over time at room temperature.

[0326] The desired time for stable bacterial or colony counts is at least 30 months, although testing is performed up to 36 months as a good goal if counts remain within ±20% of the initial number of bacteria or colonies.

[0327] Other batches of compositions made according to this application were also subjected to shelf life testing at room temperature, with compositions made with isolated species and mixtures with at least the following microorganisms: Bacillus subtilis sp., Bacillus amyloliquefaciens sp., Bacillus firmus sp., Bacillus thuringiensis sp., Bacillus simplex sp., Bacillus licheniformis sp., Bacillus velezensis sp., Pseudomonas fluorescens sp., Pseudomonas protegeans sp., Tricoderma harzianum sp., Tricoderma asperellum sp., Paecilomyces lilacinus sp., and Beauveria bassiana sp.

[0328] Current plant protection products and / or biocontrol agents containing microorganisms are known to often have a limited shelf life. Applicant was surprised to find that compositions according to the present disclosure exhibited an extended shelf life such that the microorganisms were not killed or spoiled within the typical time periods known in the art.

[0329] Applicants were also surprised by the long shelf life of the compositions according to the present disclosure. Furthermore, the compositions did not exhibit phase separation and remained stable for extended periods of time.

[0330] Example 4 An embodiment of the present disclosure for use as a nematicidal and / or nematicidal pesticide product. OR-501 (also known as pLCC or OR-N-6) was applied through a drip irrigation system to the rhizosphere of greenhouse-grown tomato plants. Tests were conducted on tomato plants grown in soil artificially inoculated with Meloidogyne incognita eggs and J2 to ensure uniform target nematode populations and reliable results.

[0331] The treatments under test are outlined in Table 20, and the timing, dates and methods of application are outlined in Table 21.

[0332] [Table 22]

[0333] [Table 23]

[0334] Experimental configuration and test methodology The test consisted of four replicates and 12 m with 24 plants (two rows). 2 It was conducted using a randomized complete block design with individual plot sizes of (6m x 2m).

[0335] The day before transplanting the tomato plants, the soil was artificially inoculated with 42,163 eggs + J2 of Meloidogyne incognita per plant.

[0336] The application of all products under test was carried out through a drip irrigation system at the planting rows (products were applied directly to the root zone). The total volume of irrigation water used to carry out the applications was 20,000 L / ha, and in practice the applications were carried out according to the following sequence: 1. 8000L / ha of water was applied to moisten the soil and ensure proper placement of the product through the area of ​​the future root system. 2. The product was diluted in 10000 L / ha of water to ensure uniform distribution in the future rhizosphere. 3. 8000L / ha of water was applied, the irrigation lines were cleared and the irrigation valves were sealed.

[0337] The following assessments were performed throughout the study: - Assessment of the severity of root nodules by visual assessment of the plant root system using the modified root-nodule index of Bridge and Page, 1980 (0-10): [Table 24]

[0338] Nematode numbers in soil: Number of Meloidogyne incognita J2 per 100cc of soil Yield was measured over several successive harvests and total fruit production (from all harvests) was calculated and expressed as: a Total yield (T / ha) b Total number of fruits / ha c Average fruit weight (g / fruit) d Phytotoxicity was assessed visually by % severity

[0339] result The results obtained for each of the main variables recorded in the study are presented below.

[0340] Severity of root club: Figure 8 shows the severity of root knots as assessed visually across the trial (47, 89 and 131 days after transplanting) in the different treatments.

[0341] Untreated plants exhibited moderate nodule severity, ranging from 4.43 (89 DAT) to 5.1 (47 DAT) in the evaluation data. The standard reference OLREDY significantly reduced nodule severity compared to the control in all three evaluation data. OR-501 achieved a numerical reduction in nodule severity compared to the control.

[0342] Nematode populations in soil: Figure 9 shows the nematode populations (number of J2 / 100cm of soil) counted in soil samples collected throughout the study. 3 ) are shown. Soil samples were collected at three different times: - 0DAT: Ensure sufficient and uniform nematode population before first application - 89 and 131 DAT: Evaluate changes in soil nematode populations following product application

[0343] At the start of the trial, before the first application, all treatments showed statistically equivalent nematode populations in the soil, with values ​​ranging from 431 to 454 J2 / 100 cm3 of soil depending on the treatment.

[0344] Both the standard references OLREDY and OR-501 significantly reduced nematode populations compared to the control at both evaluation dates (89 and 131 DAT). OLREDY and OR-501 presented statistically and numerically comparable results.

[0345] Fruit production: At the end of the trial, total tomato production was recorded for each treatment.

[0346] Figures 10, 11 and 12 show the different parameters recorded to evaluate tomato production: - Figure 10 presents the total production (yield) in tonnes / ha for the different treatments - Figure 11 presents the total number of saleable fruits harvested in the different treatments (expressed as saleable fruits / ha). - Figure 12 presents the average weight of the fruits (g / fruit) of the different treatments

[0347] Regarding yield, OLREDY and OR-501 presented numerically higher fruit production (tons / ha) compared to the untreated control. Although not significant, significant increases in yield of 33 and 25 points over the control treatment (forced 100%) were recorded for OLREDY and OR-501, respectively.

[0348] In terms of total number of saleable fruits, OLREDY and OR-501 provided numerically higher numbers of saleable fruits compared to the untreated control. Although not significant, significant increases of 32 and 23 points in number of saleable fruits were recorded for OLREDY and OR-501, respectively, over the control treatment (forced 100%).

[0349] Regarding the average fruit weight (g / fruit), all treatments presented very similar values. This result confirms the positive effect of OLREDY and OR-501 on total fruit production, since the number of saleable fruits and yield recorded in the treated subjects with respect to the control were significantly higher, but no reduction in the average fruit weight was observed.

[0350] conclusion This study, conducted under commercial conditions of tomato production, confirmed the nematicidal activity of ORO-501 against Meloidogyne incognita and its associated benefits for tomato production.

[0351] Three applications of ORO-501 through a drip irrigation system at the beginning of the crop cycle resulted in: - A numerical decrease in root nodule strength compared to the control - Significant reduction in nematode populations (J2 numbers) compared to controls throughout the study - A numerical increase in total tomato production in quantity (tons of tomatoes / ha) and number of saleable fruits, without changing the average weight of the fruits.

[0352] Application of ORO-501 at 10 L / ha was safe to crops, did not induce any kind of phytotoxicity, and also reduced the use of traditional pesticides, reducing the levels of pesticide residues in soil and crops (food or non-food crops).

[0353] Another important feature praised by OR-501 researchers and common to all formulations created by this invention is that it easily stores at room temperature for at least two years. A three- or six-month shelf life and / or storage at 5°C to -18°C (refrigerated or frozen) is much more practical for farmers and end users than biologics.

[0354] The high stability and long shelf life of compositions made according to the present invention gives the end user confidence that they will get the same rate and performance as a biologic over the shelf life of the commercial biologic.

[0355] The applicant was surprised that a carrier composition comprising an alkyl lactate (and / or its derivatives) and a carboxylic acid, when loaded with a microbial biocontrol agent, did not damage and / or destroy said microbial biocontrol agent, since it is well known in the prior art that alkyl lactates and carboxylic acids are antimicrobial as taught in EP 1 898 900 B1. This is particularly true for OR-501 (also pLCC and OR-N-6).

[0356] Example 5 Field efficacy of ORO-501 [Bacillus amyloliquefaciens (20%) + UCCa (80%)], also known as B-017-001, on melon controlling Meloidogyne incognita. Shandong Province, China (September 2022)

[0357] [Table 25]

[0358] Testing and Processing Details 1. Root drench on the day of transplanting with 1% rate (10ml / 1L) + Metalaxyl-M + Hymexazol and watering 23 days after transplanting with a dosage of 9L / ha. 2. Root dipping on the day of transplanting with 1% rate (10ml / 1L) + Metalaxyl-M + Hymexazol and irrigation with 15L / ha of CS with abamectin 3% 23 days after transplanting. 3. Root dipping with metalaxyl-M + hymexazol on the day of transplanting and irrigation with abamectin 3% CS + 3 billion / g Bacillus amyloliquefaciens (ORO-501 (also known as B-017-001 - Bacillus amyloliquefaciens + UCCa)). Reference - Commercial Paecilomyces lilacinus at a dosage of 15 kg / ha + 15 kg / ha, irrigated with 15 L / ha of CS with 3% Abamectin 23 days after transplanting.

[0359] result Field trials were conducted in a greenhouse farm at a third-party facility. After harvest, melons were collected and evaluated. Roots from plants irrigated with the ORO-501 drip + irrigation treatment were hand-pulled by farmers, while roots from other treatments (roots more affected by nematodes) were collected with a spade.

[0360] The number of healthy and infected roots, the number of healthy and infected melons, and all the ratings and statistics are included in Table 24 below.

[0361] It is noted that even the abamectin treated roots were pulled out with a spade as they were affected by nematodes, but were still shorter than the roots treated with ORO-501 dip + abamectin.

[0362] [Table 26]

[0363] 13 shows a data summary of healthy and infected melons, healthy and infected roots, and bar graphs of the percentage of healthy and infected melons and roots by treatment for melons controlling Meloidogyne incognita. Data was recorded at the end of the trial during harvest.

[0364] Figure 14 shows photographs of examples of healthy and infected roots and healthy and infected melons after harvest. The harvested melons and roots refer to treatments using composition ORO-501 (Bacillus amyloliquefaciens 20% + UCCa 80%), also known as B-017-001, a standard treatment for melons controlling Meloidogyne incognita.

[0365] Conclusion: 1. ORO-501 has good efficacy against nematodes when applied at a rate of 1% on the day of transplanting and irrigated 23 days later at a dosage of 9 L / ha, and its efficacy is estimated to last for approximately 15-20 days at this dosage. 2. ORO-501 can be mixed with fungicides in a dip. 3. The percentage of melons infected with nematodes in ORO-501 was 10.7%, which is much lower than that of Abamectin + Paecilomyces, whose percentage of melons infected with nematodes was 38.3%. 4. ORO-501 can be used to prevent nematodes in melons by irrigation on the day of transplanting and again 15-20 days later, as infection rates in melons treated with ORO-501 were 10.7%; therefore, changing the application method from dipping to irrigation on the day of transplanting is also evaluated. 5. It was clear from all included studies that composition ORO-501 provided more than just nematode control. Evaluations of fruit size, health, time of harvest, and plant and fruit architecture revealed that ORO-501 possesses the characteristics of a biostimulant and / or plant growth regulator. Its mode of action will be investigated over the next season in field trials, laboratory phenotyping systems, and greenhouse trials. 6. Other field and laboratory trials for registration are ongoing in China and elsewhere to obtain data and knowledge for future reference.

[0366] Ongoing Research and Trials Bio-Efficacy Screening - Fungicides Samples of certain embodiment agricultural compositions are under evaluation for bio-efficacy and are being evaluated in vitro against the most common or applicable plant pathogens to assess viability, shelf life, synergistic and antagonistic effects, and efficacy against other products and samples.

[0367] Growth inhibition was measured using potato dextrose agar (PDA) amended with the test compounds and compared to the growth of colonies of several fungi, with plain (unamended) PDA plates serving as controls: Aspergillus niger, Botrytis cinerea, Colletotrichum fioriniae, Fusarium moniliforme, F. oxysporum, Macrophomina phaseolina, Verticillium dahliae, and Xanthomonas arboricola pv. Juglandis, Botrytis cinerea, Fusarium graminearum, Macrophomina phaseolina, Alternaria alternata, Monolinia fructigena, Phytophthora infestans strain EU_6_A1, Phytophthora infestans strain EU_13_A2, Phytophthora infestans strain EU_36_A2, Phytophthora infestans strain EU_37_A2, and Xanthomonas arboricola pv. Cultures of the T. infestans strain EU_41_A2, particularly agriculturally viable species, are grown or adapted to grow on acidified potato dextrose agar and / or by specific means other than PDA. The improved and control plates are inoculated with mycelial plugs (5 mm diameter) and then incubated at 25°C until the control colonies approach the edge of the plates for each species. The colony radius is measured, and percent inhibition is calculated for each test compound relative to the radius of the control plate.

[0368] Greenhouse and plot trials Samples of certain embodiment agricultural compositions are undergoing evaluation in pest efficacy screening protocols and are being evaluated against other products and samples to assess performance, survival, shelf life, synergistic and antagonistic effects, and efficacy against the most common or applicable plant pathogens in greenhouse and plot trials.

[0369] Field trials are designed to test the most practical agricultural compositions against commercially available benchmark products in several countries and regions such as Europe, Brazil, the United States, South Africa, Australia, China and India.

[0370] Bio-Efficacy Screening - Insecticidal, Pesticidal, Acaricidal, Miticidal, Ovicidal, Herbicidal, Fungicidal, Virucidal, Nematicidal Tests: Samples of certain embodiments of agricultural compositions are being evaluated for bioefficacy and compared with other products and samples to evaluate viability, shelf life, synergistic and antagonistic effects, and efficacy against the most common or applicable plant pathogens in vitro. Mode of action is also being investigated. Applicant contemplates that the compositions according to the first and second aspects of the present disclosure and / or provided herein can provide an effective solution to plant pathogens and / or plant biostimulation.

[0371] In conclusion, applicants believe that the disclosure according to the first to fourth aspects of the present disclosure will at least partially ameliorate one of the known disadvantages of the prior art.

[0372] While the present invention has been described in detail with respect to specific embodiments and / or examples thereof, it will be understood that those skilled in the art, upon understanding the foregoing, will be able to readily envision modifications, variations, and equivalents to these embodiments. Accordingly, the scope of the present invention should be assessed as that of the claims, and any equivalents thereto, which are hereby appended.

Claims

1. A compound in which the OH of one C10-C22 alkyl alcohol and the COOH of one lactic acid are bonded via an ester bond, or lactyl lauryl lactylate; at least one selected from the group consisting of butanol, pentanol, hexanol, octanol, octan-2-ol, 2-ethylhexanol, nonanol, decanol, and undecanol; ２ ~C ２２ )alcohol; Glycerin or its alkyl ether, (C ２ ~C ３０ ) a humectant, which is at least one selected from the group consisting of alkylene glycol, propylene glycol, polypropylene glycol or alkyl ethers thereof, sorbitol, mannitol, dulcitol and / or polyols, and / or any combination of the foregoing; a nonionic surfactant, which is at least one selected from the group consisting of alkoxylated sorbitan fatty acid esters, alkoxylated sorbitol fatty acid esters, polyoxyethylene sorbitan monolaurate, and combinations thereof; and a diluent which is water; and microorganisms 1. An agricultural composition comprising:

2. The agricultural composition of claim 1, wherein the compound is at least one selected from the group consisting of decyl lactate, undecyl lactate, dodecyl lactate, tridecyl lactate, tetradecyl lactate, pentadecyl lactate, hexadecyl lactate, heptadecyl lactate, octadecyl lactate, nonadecyl lactate, eicosyl lactate, heneicosyl lactate, and docosyl lactate.

3. The agricultural composition described in claim 1, wherein the compound is at least one selected from the group consisting of lauryl lactate, myristyl lactate, and cetyl lactate.

4. Ethanoic acid, 2-hydroxyethanoic acid, oxoethanoic acid, ethanedioic acid, propanoic acid, propenoic acid, propynoic acid, 2-hydroxypropanoic acid, 3-hydroxypropanoic acid, 2,3-dihydroxypropanoic acid, 2-oxopropanoic acid, 3-oxopropanoic acid, 2,3-oxopropanoic acid, propanedioic acid, 2-hydroxypropanedioic acid, 2-hydroxy-3-oxopropanoic acid, 2,2-dihydroxypropanedioic acid, oxopropanedioic acid, oxirane-2-carboxylic acid, butanoic acid, 2-methylpropanoic acid, (E)-but-2-enoic acid, (Z) -but-2-enoic acid, 2-methylpropenoic acid, but-3-enoic acid, but-2-enoic acid, 2-hydroxybutanoic acid, 3-hydroxybutanoic acid, 4-hydroxybutanoic acid, 2-oxobutanoic acid, 3-oxobutanoic acid, 4-oxobutanoic acid, butanedioic acid, 2-methylpropanedioic acid, (E)-butenedioic acid, (Z)-butenedioic acid, butynedioic acid, hydroxybutanedioic acid, 2,3-dihydroxybutanedioic acid, oxobutanedioic acid, dioxobutanedioic acid, pentanoic acid, 3-methylbutanoic acid, 2-methylbutanoic acid, 2,2-dimethylpropanoic acid, 3-hydroxybutanoic acid hydroxypentanoic acid, 4-hydroxypentanoic acid, 3-hydroxy-3-methylbutanoic acid, pentanedioic acid, 2-oxopentanedioic acid, 3-oxopentanedioic acid, furan-2-carboxylic acid, tetrahydrofuran-2-carboxylic acid, hexanoic acid, hexanedioic acid, 2,3-dimethylbutanoic acid, 3,3-dimethylbutanoic acid, 2-hydroxypropane-1,2,3-tricarboxylic acid, prop-1-ene-1,2,3-tricarboxylic acid, 1-hydroxypropane-1,2-3-tricarboxylic acid, (2E,4E)-hexa-2,4-dienoic acid, hep hexanoic acid, heptanedioic acid, cyclohexanecarboxylic acid, benzenecarboxylic acid, 2-hydroxybenzoic acid, 2,2-dimethylpentanoic acid, 2,3-dimethylpentanoic acid, 2,4-dimethylpentanoic acid, 3,3-dimethylpentanoic acid, 2-ethylpentanoic acid, 3-ethylpentanoic acid, 2-methylhexanoic acid, 3-methylhexanoic acid, 2,2,3-trimethylbutanoic acid, 2-ethyl-2-methylbutanoic acid, 2-ethyl-3-methylbutanoic acid, octanoic acid, benzene-1,2-dicarboxylic acid, benzene-1,3-dicarboxylic acid, benzene-1,4-Dicarboxylic acid, 2-methylheptanoic acid, 3-methylheptanoic acid, 4-methylheptanoic acid, 5-methylheptanoic acid, 6-methylheptanoic acid, 2,2-dimethylheptanoic acid, 2,3-dimethylheptanoic acid, 2,4-dimethylheptanoic acid, 2,5-dimethylheptanoic acid, 3,3-dimethylheptanoic acid, 3,4-dimethylheptanoic acid, 3,5-dimethylheptanoic acid, 4,4-dimethylheptanoic acid, 4,5-dimethylheptanoic acid, 5,5-dimethylheptanoic acid butanoic acid, 2-ethanehexanoic acid, 3-ethanehexanoic acid, 4-ethanehexanoic acid, 5-ethanehexanoic acid, 2-octenoic acid, 3-octenoic acid, 4-octenoic acid, 5-octenoic acid, 6-octenoic acid, 7-octenoic acid, benzene-1,3,5-tricarboxylic acid, (E)-3-phenylprop-2-enoic acid, decanoic acid, decanedioic acid, undecanoic acid, dodecanoic acid, benzene-1,2,3,4,5,6-hexacarboxylic acid, tridecanoic acid, tetradecanoic acid , pentadecanoic acid, hexadecanoic acid, heptadecanoic acid, octadecanoic acid, (9Z)-octadec-9-enoic acid, (9Z,12Z)-octadeca-9,12-dienoic acid, (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid, (6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid, (6Z,9Z,12Z,15Z)-octadeca-6,9,12,15-tetraenoic acid, nonadecanoic acid, eicosanoic acid, (5Z,8Z, at least one C selected from the group consisting of (5Z,8Z,11Z,14Z)-eicosa-5,8,11-trienoic acid, (5Z,8Z,11Z,14Z)-eicosa-5,8,11,14-tetraenoic acid, (5Z,8Z,11Z,14Z,17Z)-eicosa-5,8,11,14,17-pentaenoic acid, heneicosanoic acid, docosanoic acid, (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid, and salts thereof; ２ ~C ２２ 4. The agricultural composition according to claim 1, further comprising a carboxylic acid and / or a salt thereof.

5. 4. The agricultural composition of claim 1, further comprising at least one plant hormone selected from the group consisting of abscisic acid, auxin, brassinosteroid, cytokinin, ethylene, gibberellin, jasmonate, jasmonic acid, salicylic acid, strigolactone, polyamine, nitrate, and triacontanol.

6. 4. The agricultural composition according to claim 1, further comprising a secondary metabolite.

7. 7. The agricultural composition according to claim 6, wherein the secondary metabolite is salicylic acid and / or itaconic acid.

8. An agricultural composition described in any one of claims 1 to 3, wherein the microorganism is selected from the group consisting of viruses, bacteria and fungi.

9. 4. The agricultural composition according to claim 1, further comprising a binder.

10. The binder may be selected from the group consisting of polysaccharides, sucrose, fructose, saccharose, pectin, amylopectin, gelatin, starch, modified starch, alginate, modified alginate, natural gum, modified gum, guar gum, rosin, rosin-rich tall oil, (C １ ~C ３０ ) alkyl cellulose, (C １ ~C ３０ 10. The agricultural composition of claim 9, wherein the cellulose acetate copolymer is selected from the group consisting of salts of alkylcelluloses, carboxymethylcellulose, salts of carboxymethylcellulose, sodium carboxymethylcellulose, microcrystalline cellulose, polyvinylpyrrolidone, crosslinked polyvinylpyrrolidone, dimethylaminoethyl-methacrylate copolymer, PVP / hexadecene copolymer, polyacrylates, and combinations thereof.

11. 4. The agricultural composition of any one of claims 1 to 3, further comprising an additive selected from the group consisting of preservatives, clarifying agents, antifreeze agents, hydrotropes, stabilizers, antioxidants, acidifying agents, chelating agents, complexing agents, dyes, rheology modifiers, antifoam agents, anti-drift agents, oils or other solvents, and combinations thereof.

12. The composition further comprises an anionic surfactant, wherein the anionic surfactant is: ６ ~C １８ ) alkylbenzene sulfonate, calcium dodecylbenzene sulfonate, sodium dodecylbenzene sulfonate, amine (C ６ ~C １８ ) alkylbenzene sulfonate, triethanolamine dodecylbenzene sulfonate, (C ６ ~C １８ ) alkyl ether sulfate, (C ６ ~C １８ ) alkyl ethoxylated ether sulfate, (C ６ ~C １８ ) alkyl sulfate, lauryl ether polyethoxylated sodium sulfate, lignosulfonate, phenyl sulfonate, naphthalene sulfonate, dibutyl naphthalene sulfonate, (C ６ ~C １８ ) alkyl phosphate ester, (C ６ ~C １８ ) alkoxylated sulfates, xylene sulfonates, cumene sulfonates, lignosulfonates, phenyl sulfonates, naphthalene sulfonates, dibutylnaphthalene sulfonates, alkyl polyglycol ether phosphates, polyarylphenyl ether phosphates, alkyl-sulfosuccinates, olefin sulfonates, condensation products of sulfonated naphthalene with formaldehyde, condensation products of sulfonated naphthalene with formaldehyde and phenol, optionally with urea, and condensation products of phenolsulfonic acid with formaldehyde and urea, (C ６ ~C １８ 4. The agricultural composition according to claim 1, wherein the at least one hydroxyl group is at least one selected from the group consisting of alkoxylated phosphate esters, alkyl phosphates, alkylaryl phosphates, such as tristyryl phosphate, and polycarboxylates, such as polyacrylates, maleic anhydride / olefin copolymers (including alkali metal, alkaline earth, ammonium and amine salts of the foregoing), and / or combinations thereof.

13. 2. The agricultural composition of claim 1, wherein the compound or the lactyl lactylate lauryl is present in an amount of 5 wt. % to 50 wt. % of the total wt. % of the formulated agricultural composition, the octan-2-ol is present in an amount of 0.1 wt. % to 20 wt. % of the total wt. % of the formulated agricultural composition, the glycerin is present in an amount of 1 wt. % to 30 wt. % of the total wt. % of the formulated agricultural composition, the polyoxyethylene sorbitan monolaurate is present in an amount of 1 wt. % to 50 wt. % of the total wt. % of the formulated agricultural composition, and the water is present in an amount of 1 wt. % to 80 wt. % of the total wt. % of the formulated agricultural composition.

14. 14. The agricultural composition of claim 13, further comprising a carboxylic acid present in an amount of 0.1 wt. % to 20 wt. % of the total wt. % of the formulated agricultural composition.

15. 15. The agricultural composition according to claim 13 or 14, further comprising a plant hormone present in an amount of 0.1 wt. % to 20 wt. % of the total wt. % of the formulated agricultural composition.

16. 15. The agricultural composition according to claim 13 or 14, further comprising a secondary metabolite present in an amount of 0.1 wt. % to 20 wt. % of the total wt. % of the formulated agricultural composition.

17. The agricultural composition according to claim 13 or 14, wherein the microorganisms are present in an amount of 1 wt. % to 70 wt. % of the total wt. % of the formulated agricultural composition.

18. 15. The agricultural composition of claim 13 or 14, further comprising a binder present in an amount of 0.1 wt. % to 20 wt. % of the total wt. % of the formulated agricultural composition.

19. 15. The agricultural composition of claim 13 or 14, further comprising an additive present in an amount of 0.1 wt. % to 20 wt. % of the total wt. % of the formulated agricultural composition.

20. At least one lactyl lactate selected from the group consisting of lactyl lauryl lactate, lauryl lactate, myristyl lactate, and cetyl lactate (C １０ ~C ２２ ) alkyl lactate; Octan-2-ol; Glycerin; Polyoxyethylene sorbitan monolaurate; secondary metabolites, which are salicylic acid and / or itaconic acid; Microorganisms; a binder; and water 1. An agricultural composition comprising:

21. The microorganism is selected from the group consisting of the genus Agrobacterium, the genus Bacillus, the genus Burkholderia, the genus Paenibacillus, the genus Pseudomonas, the genus Rhanella, the genus Rhizobium, the genus Saccharopolyspora, the genus Serratia, the genus Streptomyces, the genus Alternaria, the genus Aureobasidium, the genus Ampelomyces, the genus Aschersonia, the genus Aspergillus, the genus Beauveria, the genus Candida, the genus Clonostachys, the genus Coniothyrium, the genus Entomogen, the genus 21. The agricultural composition of claim 20, wherein the fungus is at least one of any species in the group of genera consisting of Phagga, Fusarium, Glomus, Hirustella, Isaria, Lecanicillium, Metarhizium, Paecilomyces, Penicillium, Pichia, Pseudozyma, Saccharomyces, Talaromyces, Trichoderma, Verticillium, Lagenidium and Baculoviridae.

22. At least one lactyl lactate selected from the group consisting of lactyl lauryl lactate, lauryl lactate, myristyl lactate, and cetyl lactate (C １０ ~C ２２ ) alkyl lactate; Octan-2-ol; Glycerin; Polyoxyethylene sorbitan monolaurate; a binder; and Water; and microorganisms 1. An agricultural composition comprising:

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