Chemical Injection Unit

Abstract

To provide a medical solution injection unit whose handling property and safety property are improved.SOLUTION: A medical solution injection unit 1 includes a tube 10. The tube 10 comprises: a center lumen 11; at least three puncture catheter ports 12a to 12c which communicate with the center lumen 11 and open at circumferentially different positions in the outer peripheral surface of the tube 10; and support mechanisms 40 which are disposed at positions respectively facing the at least three puncture catheter ports 12a to 12c with respect to the axis X of the tube 10, to support the tube 10.SELECTED DRAWING: Figure 2A

Description

[Technical Field]

[0001] The present invention relates to a chemical liquid injection unit. [Background technology]

[0002] Conventionally, treatments, examinations, and the like have been performed by inserting catheter-shaped medical instruments into tubular organs of the human body, such as blood vessels and the digestive tract. In recent years, treatments have also been performed by injecting medicinal liquids into body tissues (treatment sites) using catheter-shaped medical instruments capable of injecting medicinal liquids. In treatments using a catheter for injecting medicinal liquids, a puncture needle at the tip of the catheter, which is advanced to the outside of the catheter tube through an opening or hole provided on the outer surface of the catheter tube, is inserted into body tissue, and the medicinal liquid is injected through the puncture needle. For example, Patent Document 1 discloses a medicinal liquid injection device in which the needle portion of a needle-shaped tubular body (catheter) protrudes from a protruding hole provided in one direction on the side of the tubular body (catheter tube) and punctures a predetermined tissue inside the body, thereby enabling the medicinal liquid to be injected into the body tissue through the needle-shaped tubular body. [Prior art documents] [Patent documents]

[0003] [Patent Document 1] Patent No. 427905 Summary of the Invention [Problem to be solved by the invention]

[0004] When attempting to inject a medicinal solution into a specific body tissue as a treatment site using a catheter tube with a unilateral hole as shown in Patent Document 1, it is necessary to rotate the catheter within the blood vessel according to the position of the body tissue. In addition, there is a risk that the catheter tube will move away from the blood vessel due to the repulsive force generated when the puncture needle is inserted into the body tissue, raising safety concerns.

[0005] The present invention has been made in consideration of the above problems, and has as its object to provide a chemical liquid injection unit with improved handling properties and safety. [Means for solving the problem]

[0006] In order to achieve the above-mentioned object, the present invention first provides a drug solution injection unit (Invention 1), which includes a long tube, the tube extending in the axial direction of the tube, a center lumen into which a puncture catheter having a puncture needle at its tip can be inserted, at least three puncture catheter ports communicating with the center lumen and opening at different circumferential positions on the outer surface of the tube, and a support mechanism arranged at positions opposite each of the at least three puncture catheter ports with respect to the axis of the tube and used to support the tube.

[0007] According to this invention (Invention 1), by selecting the puncture catheter port closest to the body tissue into which the medicinal liquid needs to be injected from at least three puncture catheter ports and inserting the puncture catheter therein, the medicinal liquid can be injected into the body tissue without rotating the catheter in the blood vessel. Furthermore, by using support mechanisms arranged in positions facing the at least three puncture catheter ports, it is possible to prevent the medicinal liquid injection unit from moving in a direction away from the blood vessel due to the repulsive force generated when the puncture needle is inserted into the body tissue. In other words, according to this invention (Invention 1), it is possible to provide a medicinal liquid injection unit with improved handling and safety.

[0008] In the above invention (Invention 1), the support mechanism may include at least three support wire lumens extending in the axial direction of the tube, each into which at least one support wire can be inserted, and at least three support wire ports that communicate with each of the at least three support wire lumens and open at different circumferential positions on the outer peripheral surface of the tube (Invention 2).

[0009] According to this invention (Invention 2), a support wire port is selected that is positioned opposite the axis of the tube to the puncture catheter port from which the puncture catheter is delivered, and the support wire is delivered from this support wire port, thereby preventing the drug solution injection unit from moving away from the blood vessel due to the repulsive force generated when the puncture needle of the puncture catheter is inserted into the body tissue into which the drug solution needs to be injected.

[0010] In the above inventions (Inventions 1 and 2), the at least three puncture catheter ports may be arranged at equal intervals in the circumferential direction on the outer peripheral surface of the tube (Invention 3).

[0011] According to this invention (Invention 3), it is possible to appropriately select the puncture catheter port that is closest to the body tissue into which the medicinal liquid needs to be injected.

[0012] In the above inventions (Inventions 1-3), the at least three puncture catheter ports may be arranged at different positions in the longitudinal direction on the outer peripheral surface of the tube (Invention 4).

[0013] According to this invention (Invention 4), it is possible to more appropriately select the puncture catheter port that is closest to the body tissue to which the medicinal liquid needs to be injected.

[0014] In the above invention (Invention 4), the at least three puncture catheter ports may be arranged at equal intervals in the longitudinal direction on the outer peripheral surface of the tube (Invention 5).

[0015] According to this invention (Invention 4), it is possible to more appropriately select the puncture catheter port that is closest to the body tissue to which the medicinal liquid needs to be injected.

[0016] The above inventions (Inventions 1-5) may comprise a plurality of puncture catheter sets each including at least three puncture catheter ports, and the plurality of puncture catheter sets may be arranged at different positions in the longitudinal direction of the tube (Invention 6).

[0017] According to this invention (Invention 6), it is possible to more easily inject medicinal liquid into multiple locations in body tissues where medicinal liquid injection is required, without having to move the medicinal liquid injection unit back and forth within the blood vessel.

[0018] In the above inventions (Inventions 1-6), a radiopaque marker may be disposed on at least a part of the outer periphery of each of the at least three puncture catheter ports (Invention 7).

[0019] According to this invention (Invention 7), the position of each puncture catheter port can be easily confirmed by X-ray.

[0020] In the above invention (Invention 1), the support mechanism may include a balloon member having a balloon (Invention 8).

[0021] According to this invention (Invention 8), a balloon member is selected as a support mechanism that is positioned opposite the puncture catheter port through which the puncture catheter is delivered and the axis of the tube, and by inflating the balloon of this balloon member, it is possible to prevent the drug solution injection unit from moving in a direction away from the blood vessel due to the repulsive force when the puncture needle of the puncture catheter is inserted into the body tissue into which the drug solution needs to be injected. [Effects of the Invention]

[0022] According to the present invention, the puncture needle can be inserted into multiple target sites without rotating the catheter within the blood vessel, thereby providing a liquid medicine injection unit with improved handling and safety. [Brief explanation of the drawings]

[0023] [Figure 1] 1 is a schematic explanatory diagram showing the structure of a chemical liquid injection unit according to an embodiment of the present invention; [Figure 2A] 2 is a see-through perspective view schematically showing a part of a tube provided in the chemical liquid injection unit of FIG. 1. FIG. [Figure 2B]2B is a diagram showing an example of a state in which a puncture catheter and a support wire are inserted into the tube of FIG. 2A together with a blood vessel. FIG. [Figure 3A] 2B is a vertical projection of the tube of FIG. 2A relative to its axial direction. [Figure 3B] 2C is a vertical projection of the tube of FIG. 2B relative to its axial direction. [Figure 4A] FIG. 2B shows an example of placing a radiopaque marker at the puncture catheter port of the tube of FIG. 2A. [Figure 4B] FIG. 2B shows another example of placing a radiopaque marker at the puncture catheter port of the tube of FIG. 2A. [Figure 5A] 10 is a perspective view schematically showing a tube and a part of a tip end portion of a liquid medicine injection unit according to a first modification. FIG. [Figure 5B] FIG. 5B is a diagram showing an example of a guide wire being inserted into the tube of FIG. 5A. [Figure 6A] 10 is a see-through perspective view schematically showing a part of a tube included in a chemical liquid injection unit of Modification 2. FIG. [Figure 6B] 6B is a diagram showing an example of a state in which a puncture catheter and a support wire are inserted into the tube of FIG. 6A. FIG. [Figure 7A] 6B is a vertical projection of the tube of FIG. 6A relative to its axial direction. [Figure 7B] 6C is a vertical projection of the tube of FIG. 6B relative to its axial direction. [Figure 8] 13 is a see-through perspective view schematically showing a part of a tube included in a chemical liquid injection unit of Modification 3. FIG. [Figure 9] FIG. 10 is a schematic explanatory diagram showing the structure of a chemical liquid injection unit according to a fourth modification. [Figure 10] 10 is a see-through perspective view schematically showing a part of a tube and a balloon member included in the chemical liquid injection unit of FIG. 9. FIG. [Figure 11] 10 is a vertical projection of the tube of FIG. 9 along its axial direction, along with a balloon member. DETAILED DESCRIPTION OF THE INVENTION

[0024] Hereinafter, embodiments of the present invention will be described with reference to the drawings. The present invention is not limited to the embodiments described below, and the described embodiments are merely examples for explaining the technical features of the present invention. Furthermore, the shapes and dimensions shown in the drawings are shown merely to facilitate understanding of the contents of the present invention, and do not accurately reflect the actual shapes and dimensions.

[0025] FIG. 1 is a schematic diagram illustrating the structure of a drug solution injection unit 1 according to an embodiment of the present invention. The drug solution injection unit 1 includes a long tube 10. The drug solution injection unit 1 is a drug solution injection catheter used to inject a drug solution into a specific body tissue that is a treatment site. The drug solution injection unit 1 is inserted into a blood vessel of a heart that has suffered a myocardial infarction, for example, and is used when injecting cultured myocardial cells into a specific myocardium.

[0026] In this specification, the term "distal side" refers to the direction along the axial X direction of the tube 10 constituting the liquid medicine injection unit 1, in which the liquid medicine injection unit 1 advances toward a specific internal tissue that is the treatment site. The term "proximal side" refers to the direction along the axial X direction of the tube 10 constituting the liquid medicine injection unit 1, in the opposite direction to the distal side. The term "distal side" refers to the distal end of any member or site, and the term "proximal end" refers to the proximal end of any member or site. In FIG. 1, the left side of the illustration is the "distal side" that is inserted into the body, and the right side is the "proximal side" that is operated by the operator.

[0027] As shown in FIG. 1, the liquid medicine injection unit 1 further includes a tip portion 20 connected to the tip of the tube 10, and a branch socket 30 connected to the base end of the tube 10.

[0028] 2A is a see-through perspective view schematically illustrating a portion of the tube 10 included in the liquid medicine injection unit 1 of FIG. 1. FIG. 2A generally corresponds to the portion designated by the symbol A in FIG. 1. As shown in FIG. 2A, the tube 10 includes a center lumen 11 extending in the axial direction X of the tube 10, at least three puncture catheter ports 12a to 12c opening at different circumferential positions on the outer peripheral surface 10s of the tube 10, and a support mechanism 40 disposed at positions facing the at least three puncture catheter ports 12a to 12c with respect to the axial direction X of the tube 10 and used to support the tube 10. The center lumen 11 is a lumen into which a puncture catheter Cp having a puncture needle at its tip can be inserted. The puncture catheter ports 12a to 12c each communicate with a common center lumen 11.

[0029] In this specification, "support mechanisms 40 arranged at positions facing the at least three puncture catheter ports 12a to 12c with respect to the axis X of the tube 10" means that, in a vertical projection view of the tube 10 with respect to the axis X direction, the support mechanisms 40 are arranged at positions facing the respective puncture catheter ports 12a to 12c with respect to the axis X of the tube 10. "Vertical projection view of the tube 10 with respect to the axis X direction" means a projection view of the tube 10 onto a plane perpendicular to the axis X of the tube 10.

[0030] In this embodiment, the support mechanism 40 includes at least three support wire lumens 13a-13c extending in the axial direction X of the tube 10, and at least three support wire ports 14a-14c opening at different circumferential positions on the outer peripheral surface 10s of the tube 10. The support wire lumens 13a-13c are each a lumen into which at least one support wire Ws can be inserted. The support wire ports 14a-14c are in communication with the support wire lumens 13a-13c, respectively.

[0031] Fig. 3A is a vertical projection view of the tube 10 in Fig. 2A in the axial X direction. As shown in Fig. 3A, in the vertical projection view of the tube 10 in the axial X direction, the center lumen 11 is located in the center so as to include the axis X of the tube 10. The support wire lumens 13a to 13c are arranged outside the center lumen 11 so as to surround the center lumen 11.

[0032] The inner diameter of the center lumen 11 is configured to be larger than the inner diameters of the support wire lumens 13a to 13c.

[0033] 3A, in a vertical projection view of the tube 10 in the direction of the axis X, the puncture catheter ports 12a to 12c and the support wire ports 14a to 14c are arranged in positions that face each other with respect to the axis X of the tube 10. Note that the phrase "the puncture catheter ports 12a to 12c and the support wire ports 14a to 14c are arranged in positions that face each other with respect to the axis X of the tube 10" means that the puncture catheter ports 12a to 12c and the support wire ports 14a to 14c may be arranged in positions that roughly face each other with respect to the axis X, and does not necessarily mean that the puncture catheter ports 12a to 12c and the support wire ports 14a to 14c are arranged in positions that face each other with respect to the axis X, as shown in FIG. The opening center 14d of the support wire ports 14a to 14c may be located in a range where the angle β defined by the imaginary line L passing through the opening center 12d of the puncture catheter ports 12a to 12c and the axis X and the axis X satisfies -45°≦β≦45°.

[0034] FIG. 2B is a diagram showing an example of the tube 10 of FIG. 2A when the puncture catheter Cp and the support wire Ws are inserted, along with the blood vessel BV. FIG. 3B is a vertical projection of the tube 10 of FIG. 2B in the direction of the axis X. Note that the blood vessel BV is omitted in FIG. 3B. As shown in FIGS. 2B and 3B, the liquid medicine injection unit 1 can select one of the at least three puncture catheter ports 12a to 12c that is closest to the body tissue into which the liquid medicine needs to be injected, and insert the puncture catheter Cp therein. The puncture catheter Cp has a puncture needle at its tip. This allows the liquid medicine to be injected into the body tissue without rotating the liquid medicine injection unit 1 within the blood vessel BV.

[0035] As shown in Figures 2B and 3B, in the drug solution injection unit 1, one of the puncture catheter ports 12a to 12c from which the puncture catheter Cp is to be delivered is selected from the support wire ports 14a to 14c and the one positioned opposite the axis X of the tube 10, and the support wire Ws is delivered from there and abutted against the inner wall of the blood vessel BV, thereby preventing the drug solution injection unit 1 from moving in a direction away from the blood vessel BV due to the repulsive force generated when the puncture needle of the puncture catheter Cp is inserted into the body tissue.

[0036] Two or more of the at least three support wire ports 14a-14c may be selected as the support wire ports 14a-14c from which the support wire Ws1 is delivered. That is, by delivering the support wire Ws from each of two or more of the at least three support wire ports 14a-14c, the liquid medicine injection unit 1 may be prevented from moving in a direction away from the blood vessel BV. Alternatively, by delivering two or more support wires Ws from one of the at least three support wire ports 14a-14c, the liquid medicine injection unit 1 may be prevented from moving in a direction away from the blood vessel BV.

[0037] As shown in Fig. 3A, the at least three puncture catheter ports 12a to 12c may be arranged at equal intervals in the circumferential direction on the outer peripheral surface 10s of the tube 10. In the example of Fig. 3A, the three puncture catheter ports 12a to 12c are arranged at equal intervals in the circumferential direction on the outer peripheral surface 10s of the tube 10 so that the angle α defined by the line L and the axis X is 120°. This makes it possible to more appropriately select one of the at least three puncture catheters 12a to 12c that is closest to the body tissue into which the medicinal solution needs to be injected.

[0038] 2A, the at least three puncture catheter ports 12a to 12c may be arranged at different positions in the longitudinal direction on the outer peripheral surface 10s of the tube 10. This allows appropriate selection of one of the at least three puncture catheter ports 12a to 12c that is closest to the body tissue into which the medicinal liquid needs to be injected.

[0039] The at least three puncture catheter ports 12a to 12c may be arranged at equal intervals in the longitudinal direction on the outer peripheral surface 10s of the tube 10. This makes it possible to more appropriately select one of the at least three puncture catheter ports 12a to 12c that is closest to the body tissue into which the medicinal liquid needs to be injected.

[0040] FIG. 4A is a diagram showing an example in which radiopaque markers 15 are arranged on the puncture catheter ports 12a to 12c of the tube 10 of FIG. 2A. FIG. 4B is a diagram showing another example in which radiopaque markers 15a to 15c are arranged on the puncture catheter ports 12a to 12c of the tube 10 of FIG. 2A. In the drug solution infusion unit 1, the radiopaque markers 15a to 15c may be arranged on at least a portion of the outer periphery of each of at least three puncture catheter ports 12a to 12c. This allows the position of each puncture catheter port 12a to 12c to be easily confirmed by X-ray. The radiopaque markers 15a to 15c may be arranged in any manner so long as the position of each puncture catheter port 12a to 12c can be confirmed by X-ray, and there are no particular limitations on the arrangement method. For example, as shown in FIG. 4A, the radiopaque markers 15a to 15c may be arranged to surround the outer periphery of the puncture catheter ports 12a to 12c. As shown in FIG. 4B, the radiopaque markers 15a to 15c may be arranged linearly in the tangential direction of the outer periphery of the puncture catheter ports 12a to 12c.

[0041] The distal end portion 20 has a distal end opening 21. The distal end opening 21 may be in communication with the center lumen 11. With this configuration, the guidewire Wg can be guided to the distal end opening 21 of the distal end portion 20 via the center lumen 11. That is, in the drug solution injection unit 1, the center lumen 11 may also serve as a guidewire lumen into which the guidewire Wg can be inserted.

[0042] The branch socket 30 is configured to allow attachment of three connectors (not shown). For example, the first and second connectors may be connected to the center lumen 11, and the third connector may be connected to the support wire lumens 13a to 13c. In this case, for example, a puncture catheter Cp inserted from the opening of the first connector can be guided to one of the puncture catheter ports 12a to 12c via the center lumen 11, and a guide wire Wg inserted from the opening of the second connector can be guided to the distal end opening 21 via the center lumen 11. A support wire Ws inserted from the opening of the third connector can be guided to one of the support wire ports 14a to 14c via one of the support wire lumens 13a to 13c.

[0043] (Variation 1) FIG. 5A is a see-through perspective view schematically illustrating a tube 101 and a portion of a distal end portion 201 included in a liquid medicine injection unit 100 of Modification 1. FIG. 5A generally corresponds to the portion designated by reference symbol B in FIG. 1. FIG. 5B is a view illustrating an example of a state in which a guidewire Wg is inserted into the tube 101 of FIG. 5A. As shown in FIGS. 5A and 5B, the liquid medicine injection unit 100 may include, in addition to the center lumen 11, a guidewire lumen 16 into which a guidewire Wg can be inserted. The guidewire lumen 16 extends in the axial direction of the tube 101 and communicates with a distal end opening 21 of the distal end portion 201. As shown in FIGS. 5A and 5B, a guidewire port 17 communicating with the guidewire lumen 16 may be disposed on the outer circumferential surface 101s of the tube 101. A plurality of guidewire ports 17 may be present at different circumferential positions of the tube 101. Each of the plurality of guidewire ports 17 may communicate with a single common center lumen 11.

[0044] Regarding the three connectors (not shown) that can be attached to the branch socket 30, in Modification 1, for example, a first connector may be connected to the center lumen 11, a second connector may be connected to the guidewire lumen 16, and a third connector may be connected to the support wire lumens 13a to 13c. In this case, for example, the guidewire Wg inserted from the opening of the second connector can be guided to the distal end opening 21 via the guidewire lumen 16.

[0045] In Modification 1, the inner diameter of the guidewire lumen 16 is configured to be larger than the inner diameters of the support wire lumens 13a to 13c. The inner diameter of the guidewire lumen 16 and the inner diameter of the center lumen 11 may be the same or different. The inner diameter of the guidewire lumen 16 may also be configured to be smaller than the inner diameter of the center lumen 11.

[0046] (Variation 2) 6A is a see-through perspective view schematically illustrating a portion of a tube 102 included in a liquid injection unit 200 of Modification 2. In the liquid injection unit 200, the support mechanism 40 includes at least three first support wire lumens 13a-13c extending in the axial direction X of the tube 102, at least three first support wire ports 14a-14c opening at different circumferential positions on the outer peripheral surface 102s of the tube 102, at least three second support wire lumens 18a-18c extending in the axial direction X of the tube 102, and at least three second support wire ports 19a-19c opening at different circumferential positions on the outer peripheral surface 102s of the tube 102. The first support wire lumens 13a-13c correspond to the support wire lumens 13a-13c described above. The first support wire ports 14a-14c correspond to the support wire ports 14a-14c described above. Each of the second support wire lumens 18a to 18c is a lumen into which at least one support wire Ws can be inserted. The second support wire ports 19a to 19c communicate with each of the second support wire lumens 18a to 18c.

[0047] Fig. 7A is a vertical projection view of the tube 102 in Fig. 6A in the axial X direction. In the example shown in Fig. 7A, in the vertical projection view of the tube 102 in the axial X direction, the second support wire lumens 18a-18c are arranged at positions different from the first support wire lumens 13a-13c in the axial X direction, that is, at positions that do not overlap with the first support wire lumens 13a-13c in the axial X direction. The second support wire lumens 18a-18c are arranged outside the center lumen 11 so as to surround the center lumen 11.

[0048] The inner diameter of the center lumen 11 is configured to be larger than the inner diameters of the second support wire lumens 18a to 18c. The inner diameters of the second support wire lumens 18a to 18c may be the same as or different from the inner diameters of the first support wire lumens 13a to 13c.

[0049] 7A, in a vertical projection view of the tube 102 in the direction of the axis X, the puncture catheter ports 12a to 12c and the second support wire ports 19a to 19c are arranged in positions facing each other with respect to the axis X of the tube 102. Note that the phrase "the puncture catheter ports 12a to 12c and the second support wire ports 19a to 19c are arranged in positions facing each other with respect to the axis X of the tube 102" means that the puncture catheter ports 12a to 12c and the second support wire ports 19a to 19c are arranged in positions that roughly face each other with respect to the axis X, and does not necessarily mean that the puncture catheter ports 12a to 12c and the second support wire ports 19a to 19c are arranged in positions that directly face each other with respect to the axis X. The opening centers 19d of the second support wire ports 19a to 19c may be located in a range in which the angle β defined by the imaginary line L and the axis X satisfies -45°≦β≦45°. 7A , the first support wire ports 14a-14c and the second support wire ports 19a-19c that are closest to each other in the direction of the axis X may be disposed such that the midpoint Rc of an imaginary line R connecting the opening center 14d of the first support wire ports 14a-14c and the opening center 19d of the second support wire ports 19a-19c faces the puncture catheter ports 12a-12c with respect to the axis X of the tube 102. The definition of "facing the axis X of the tube 102" is as described above. That is, the midpoint Rc may be located in a range where the angle β defined by the imaginary line L and the axis X satisfies -45°≦β≦45°.

[0050] Fig. 6B is a diagram showing an example of when the puncture catheter Cp and the support wire Ws are inserted into the tube 102 of Fig. 6A. Fig. 7B is a vertical projection view of the tube 102 of Fig. 6B in the direction of the axis X. As shown in Figs. 6B and 7B, in the drug solution injection unit 200 of Modification 2, one of the puncture catheter ports 12a to 12c from which the puncture catheter Cp is to be delivered is selected from the first support wire ports 14a to 14c and the second support wire ports 19a to 19c, and a port positioned opposite the axis X of the tube 10 is selected. The support wire Ws is delivered from each port and brought into contact with the inner wall of the blood vessel BV. This makes it possible to prevent the drug solution injection unit 200 from moving in a direction away from the blood vessel BV due to a repulsive force generated when the puncture needle of the puncture catheter Cp is inserted into a specific body tissue that is a treatment site.

[0051] Two or more of the at least three second support wire ports 19a-19c may be selected as the second support wire ports 19a-19c from which the support wire Ws is delivered. That is, by delivering the support wire Ws from each of two or more of the at least three second support wire ports 19a-19c, the liquid medicine injection unit 200 may be prevented from moving in a direction away from the blood vessel BV. Furthermore, by delivering two or more support wires Ws from one of the at least three second support wire ports 19a-19c, the liquid medicine injection unit 200 may be prevented from moving in a direction away from the blood vessel BV.

[0052] (Variation 3) 8 is a see-through perspective view schematically showing a portion of the tube 103 included in the liquid medicine injection unit 300 of Modification 3. The liquid medicine injection unit 300 of Modification 3 has a plurality of puncture catheter sets Sp (Sp1, Sp2), each of which has at least three puncture catheter ports 12a to 12c, and has the same configuration as the liquid medicine injection unit 1 including the tube 10, except that the plurality of puncture catheter sets Sp are arranged at different positions in the longitudinal direction of the tube 103.

[0053] The liquid medicine injection unit 300 includes a plurality of puncture catheter sets Sp (Sp1, Sp2) arranged at different positions in the longitudinal direction of the tube 103. This increases the number of options for the puncture catheter ports 12a to 12c from which the puncture catheters Cp are delivered, making it easier to inject liquid medicine into a plurality of locations in a specific body tissue that is the treatment site, without having to move the liquid medicine injection unit 300 back and forth within the blood vessel BV.

[0054] Here, a set including at least three support wire ports 14a-14c is defined as a support set Ss. As shown in Fig. 8, in the liquid injection unit 300 of Modification 3, the support set Ss may be disposed between the puncture catheter set Sp1 and the puncture catheter set Sp2 in the direction of axis X. With this configuration, the support set Ss can prevent the liquid injection unit 300 from moving away from the blood vessel BV, whether the puncture wire ports 12a-12c of the distal puncture catheter set Sp1 or the proximal puncture wire set Sp2 are used.

[0055] The drug solution injection unit 300 may include multiple support sets Ss. For example, from the distal end to the proximal end, the following may be arranged in this order: puncture catheter set Sp, support set Ss, puncture catheter set Sp, support set Ss, ... When multiple support sets Ss are included, the support wire ports 14a to 14c of the multiple support sets Ss may each communicate with a common support wire lumens 13a to 13c.

[0056] The embodiment of Modification 2 can also be applied to the liquid medicine injection unit 300 of Modification 3. That is, the liquid medicine injection unit 300 may include a first support set Ss1 including at least three first support wire ports 14a-14c, and a second support set Ss2 including at least three second support wire ports 19a-19c. The liquid medicine injection unit 300 may include a plurality of second support sets Ss2.

[0057] (Variation 4) 9 is a schematic diagram illustrating the structure of a liquid medicine injection unit 400 of Modification 4. In the liquid medicine injection unit 400, the support mechanism 40 includes a balloon member 50 having a balloon 51. That is, the liquid medicine injection unit 400 of Modification 4 has the same configuration as the liquid medicine injection unit 1, except that the puncture catheter ports 12a to 12c and the balloon member 50 are positioned opposite each other with respect to the axis X of the tube 10.

[0058] FIG. 10 is a see-through perspective view schematically showing a portion of the tube 10 and balloon member 50 included in the drug solution injection unit 400. FIG. 10 generally corresponds to the portion designated by the symbol A' in FIG. 9. In addition to the balloon 51, the balloon member 50 further includes a long tube 52 and a distal tip 53 attached to the distal end of the tube 52. The balloon 51 is provided between the distal tip 53 and the tube 52. The balloon member 50 may be integrated with the tube 10 at its proximal end, or may be separate from the tube 10. When the balloon member 50 is separate from the tube 10, the balloon member 50 may further include a connector (not shown) connected to the proximal end of the tube 52.

[0059] The balloon member 50 can supply fluid to the internal space of the balloon 51 via the tube 52. This causes the balloon 51 to expand.

[0060] 11 is a diagram showing a vertical projection of the tube 10 in FIG. 9 with respect to the axis X direction, together with the balloon member 50. As shown in FIG. 11, in the vertical projection of the tube 10 with respect to the axis X direction, the puncture catheter ports 12a to 12c and the balloon member 50 are disposed in positions facing each other with respect to the axis X of the tube 10. Note that the phrase "the puncture catheter ports 12a to 12c and the balloon member 50 are disposed in positions facing each other with respect to the axis X of the tube 10" means that the puncture catheter ports 12a to 12c and the balloon member 50 are disposed in positions that roughly face each other with respect to the axis X, and does not necessarily mean that the puncture catheter ports 12a to 12c and the balloon member 50 are disposed in positions that directly face each other with respect to the axis X, as shown in FIG. 11. For example, the center 50a of the balloon member 50 may be located in a range in which the angle β defined by the imaginary line L and the axis X satisfies -45°≦β≦45°.

[0061] In the drug solution injection unit 400, the support mechanism 40 includes a balloon member 50 having a balloon 51, so that the drug solution injection unit 400 can be prevented from moving in a direction away from the blood vessel BV due to the repulsive force generated when the puncture needle is inserted into a specific body tissue that is the treatment site.

[0062] Two or more balloon members 50 may be used as the balloon member 50. That is, two or more balloons 51 may function as the support mechanism 40. In this case, the stability of the drug solution injection unit 400 is further improved. FIG. 11 shows an example in which three balloon members 50 are used as the balloon member 50.

[0063] The center lumen 11, the support wire lumens (first support wire lumens) 13a-13c, the second support wire lumens 18a-18c, and the guidewire lumen 16 described above are tubular bodies formed from resin. The resin material from which these lumen tubular bodies are formed is not particularly limited, but a resin with good sliding properties with other members is preferred. Examples of suitable resins include fluorine-based resins such as PTFE (polytetrafluoroethylene), PVDF (polyvinylidene fluoride), PFA (perfluoroalkoxyalkane), FEP (perfluoroethylene propene), and ETFE (ethylene tetrafluoroethylene), as well as PE (polyethylene) and PP (polypropylene). The tubular bodies forming the center lumen 11, the support wire lumens (first support wire lumens) 13a-13c, the second support wire lumens 18a-18c, and the guidewire lumen 16 may be formed from the same resin material or different resin materials.

[0064] A reinforcing member (not shown) may be disposed on the outer periphery of the tube body. The reinforcing member may be, for example, a braided body (metal braid layer) formed by weaving a plurality of wires into a mesh. The reinforcing member may cover the entire outer periphery of the tube body, or may cover only a portion of the outer periphery of the tube body. Alternatively, a resin outer layer tube (not shown) in which the reinforcing member is embedded may be disposed on the outer periphery of the tube body.

[0065] The tubes 10, 101, 102, and 103 are formed from resin. For example, the tube 10 covers the tube body constituting the center lumen 11 and the tube bodies constituting the support wire lumens (first support wire lumens) 13a to 13c. The resin material forming the tubes 10, 101, 102, and 103 is not particularly limited, and examples thereof include polyamide, polyamide elastomer, polyester, polyurethane, and polyurethane elastomer. The tubes 10, 101, 102, and 103 may be formed from a single resin material, or may be divided into multiple regions and formed using multiple resin materials with different properties. Furthermore, the resin forming the tubes 10, 101, 102, and 103 may contain tungsten powder, and the hardness of the resin may be changed depending on the content of tungsten powder. By including tungsten powder, which is an X-ray opaque powder, in the resin forming tubes 10, 101, 102, and 103, a technician such as a doctor can accurately determine the position of medical solution injection unit 1 during treatment.

[0066] While the liquid medicine injection unit according to the present invention has been described above with reference to the drawings, the present invention is not limited to the above-described embodiment and various modifications are possible. For example, in the above-described embodiment, the liquid medicine injection unit is described as a catheter used to inject a liquid medicine into a specific body tissue that is a treatment site. However, the catheter to which the liquid medicine injection unit of the present invention is applied is not limited to applications for liquid medicine injection and may be applied to, for example, an endoscope. [Explanation of symbols]

[0067] 1,100,200,300,400 Chemical injection unit 10,101,102,103 Tube 11 Center Lumen 12a~12c Puncture catheter port 13a to 13c Support wire lumen (first support wire lumen) 14a to 14c Support wire port (first support wire port) 15a~15c Radiopaque markers 16 Guidewire lumen 17 Guidewire port 18a~18c Second support wire lumen 19a-19c Second support wire port 20,201 Tip 21 Tip opening 30-branch socket 40 Support mechanism 50 Balloon member 51 Balloon 52 tubes 53 Tip Sp Puncture Catheter Set Ss Support Set Cp puncture catheter Ws Support wire Wg Guidewire

Claims

[Claim 1] Including long tubes, The tube a central lumen extending in the axial direction of the tube and into which a puncture catheter having a puncture needle at its tip can be inserted; At least three puncture catheter ports communicating with the central lumen and opening at different circumferential positions on the outer circumferential surface of the tube; a support mechanism disposed at a position opposite each of the at least three puncture catheter ports with respect to the axis of the tube, the support mechanism being used to support the tube; The support mechanism includes: at least three support wire lumens extending in the axial direction of the tube, each of which can receive at least one support wire; and at least three support wire ports that communicate with the at least three support wire lumens, respectively, and that open at different circumferential positions on the outer peripheral surface of the tube.

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