System for producing optical radiation to neutralize microorganisms
The system uses narrow wavelength optical radiation to induce resonance in microorganisms, ensuring effective neutralization without harming human tissues or materials, addressing the health and structural risks of traditional UV systems.
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2022-07-11
- Publication Date
- 2026-03-10
AI Technical Summary
Existing systems that use UV light radiation to neutralize microorganisms, such as bacteria and viruses, pose risks to human health due to potential damage to human DNA and RNA, and can cause structural changes in materials, necessitating strict dose limits and limitations on their use.
A system that emits optical radiation with narrow wavelength bands, inducing optical resonance in microorganisms without harming human tissues, using LED light sources or lasers, and optionally including optical devices and filters to focus and select wavelengths, ensuring safe and effective neutralization.
The system effectively neutralizes microorganisms by inducing optical resonance, maintaining high power density within the microorganisms while avoiding harm to human tissues and materials, thus overcoming the limitations of traditional UV radiation.
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Abstract
Description
[Technical Field]
[0001] The present invention relates to a system for producing optical radiation to neutralize microorganisms.
[0002] The term "microorganism" refers to both bacteria and viruses, but also any pathogen such as fungi, algae, spores, toxins, proteins, parasites, etc.
[0003] In particular, the present invention also relates to the construction of a system configured to generate light radiation with technical properties (such as weight length), for example to inhibit microorganisms, such as bacteria and viruses, in particular SARS COV-coronavirus 2, through the modification of the genetic heritage of the microorganisms themselves.
[0004] The expression "modification of the genetic heritage" means the modification of at least one nucleic acid (DNA or RNA).
[0005] In general, the optical radiation produced by the system can be used to transfer an amount of energy to a microorganism that causes optical resonance in the microorganism itself.
[0006] Optical resonance induces irreversible physiological and morphological transformations in the microorganisms.
[0007] If the microorganism is a virus, specifically the SARS COV-2 coronavirus, the light radiation produced by the system causes irreversible damage to the genetic material of the SARS COV-2 coronavirus.
[0008] In the following description, reference is made to a system used to neutralize any microorganism comprising at least one first membrane.
[0009] In reality, a microorganism may have multiple membranes.
[0010] When a microorganism has a first membrane and a second membrane, the first membrane may be an outer membrane and the second membrane may be an inner membrane, i.e., the second membrane is disposed in an interior volume bounded by the first membrane.
[0011] In one example, when the organism is a virus with two membranes, the first membrane may be the pericapsid and the second membrane may be the capsid.
[0012] In a further example, when the organism is a virus having three membranes, the first membrane is the supercapsid, the second membrane is the pericapsid, and the third membrane is the capsid.
[0013] The same system can be used to the same advantage for different purposes.
[0014] In a first example, the system can be used to disinfect or sterilize any public or private environment intended to receive people, such as hospices, hospital wards, operating rooms, laboratories, cinemas, theatres, airplanes, trains, restaurants, bars, discos, gyms, swimming pools, etc.
[0015] In a second example, the system can be used to disinfect or sterilize any object, such as an instrument, product, or any fluid, such as a liquid or gas.
[0016] In a third example, the system can be used to sterilize food and beverages even in industrial production cycles (eg, sterilization of Salmonella, botulinum, etc.).
[0017] In further examples, the system may also be used in the medical field to reduce local viral load (e.g., present in the airways and / or alveoli of the respiratory system and / or in the patient's blood) or to treat dermatological changes or infected wounds. [Background technology]
[0018] Generally, microorganisms are organisms that are invisible to the human eye.
[0019] The microorganism comprises genetic material, in particular at least one nucleic acid, such as DNA and / or RNA.
[0020] Bacteria can be between 0.2 and 10 μm in size, and viruses between 0.015 and 0.25 μm.
[0021] As is known, viruses are microorganisms that can only be seen with an electron microscope.
[0022] Furthermore, viruses cannot sustain autonomous life and require the metabolic machinery of the cell, so they are forced to infect another organism in order to live and replicate.
[0023] It is also known that UV radiation can interact with nucleic acids, DNA and RNA, causing alterations in genetic makeup.
[0024] Thus, systems are known that are capable of emitting UV light radiation in order to modify the genetic heritage of microorganisms.
[0025] On the one hand, if the use of UV light radiation has the advantage of having a bactericidal effect on viruses or bacteria, on the other hand, the disadvantage of using UV light radiation is that UV light radiation also interacts with human DNA and RNA, causing harm to people who are directly affected by the light radiation, even if the intensity of the light radiation is reduced.
[0026] Furthermore, the time of exposure to photoradiation is long enough to result in a significant reduction in the viral / bacterial population.
[0027] Therefore, in the case of viruses such as coronaviruses, especially SARS-CoV-2, emitting UV light radiation against these viruses to human tissue would not only neutralize the virus, but also damage the human tissue with harmful tumor effects.
[0028] For this reason, namely due to the harmful oncogenic effects of UV light radiation on human tissue, the use of UV light radiation is prohibited in the presence of humans, and in particular its direct application to the human body.
[0029] The use of UV light radiation is restricted by strict limits: the maximum dose calculated over an 8-hour time interval is 30 J / m 2 is.
[0030] Furthermore, in the case of cleaning surfaces or objects made of solid or glassy materials, it must be taken into account that long UV irradiation times may be able to cause structural changes in the solid or glassy material.
[0031] Additional systems can generate light radiation to disinfect or sterilize or neutralize viruses / bacteria.
[0032] These systems comprise a light source having a wavelength such as a laser, emitting blue or red light radiation that, as verified experimentally but not theoretically, can cause alterations in the genetic heritage of microorganisms.
[0033] However, in addition to the laser, it is necessary to use photosensitizers or dyes or other substances that are not easy to find and therefore represent a limitation in the use of the system.
[0034] For example, when the laser is a pulsed laser at high frequencies (on the order of femtoseconds), the presence of a photosensitizer is not necessary to emit blue light.
[0035] However, the disadvantage is that such lasers are difficult to find and use.
[0036] Furthermore, the use of wavelengths in the visible or infrared spectrum to inhibit microorganisms is unknown. Summary of the Invention
[0037] The goal of the present invention is to overcome said disadvantages and to provide a system configured to emit optical radiation that, when directed at a person, is capable of neutralizing said microorganisms, in particular bacteria and viruses, more particularly SARS-COV2 coronavirus, on an object or on the tissues of the human body, without said tissues being damaged.
[0038] In particular, the system is designed to emit UV light radiation having wavelengths falling within a narrow band, which allows the UV light radiation to interact with microorganisms, causing an optical resonance that can neutralize the microorganisms.
[0039] On the one hand, the energy transfer from the light radiation to the microorganisms makes it possible to neutralize the microorganisms, and on the other hand, although this light radiation has a high power density inside the microorganisms because it is amplified inside the microorganisms due to the effect of the resonance phenomenon, this light radiation is not harmful to healthy tissues and therefore not harmful to people's health.
[0040] Object of the invention An object of the present invention is therefore a system for generating optical radiation for neutralizing microorganisms as claimed in claim 1.
[0041] Further embodiments are disclosed in the dependent claims.
[0042] The present invention will now be described, by way of example and not limitation, in accordance with embodiments thereof, with particular reference to the accompanying figures. [Brief explanation of the drawings]
[0043] [Figure 1] FIG. 1 is a schematic diagram of the system that is the subject of the present invention. [Figure 2A] FIG. 2A is a schematic diagram showing a microorganism, represented by a sphere, and light radiation, represented by a sine wave, that is generated by the system of FIG. 1 and is likely to impinge on the microorganism. [Figure 2B] FIG. 2B is a schematic diagram showing a microorganism in which optical radiation is partially trapped by optical resonance, bouncing from one part of the microorganism's inner wall to another part of the same inner wall, resulting in an increase in the intensity of the optical radiation and the transfer of a large amount of energy in the form of heat to the inner wall, while further optical radiation is likely to impinge on the microorganism. [Figure 2C] FIG. 2C is a schematic diagram showing a microorganism where the additional light radiation is partially trapped while additional light radiation is likely to impinge on the microorganism, resulting in an ever-increasing intensity of the light radiation inside the membrane and an increasing amount of energy being transferred in the form of heat to the inner wall of the microorganism. [Figure 3] Figure 3 shows a cross-sectional front view of the SARS-COV2 virus model for numerical simulations. [Figure 4] FIG. 4 shows a graph representing the electric field normalized to the input electric field as a function of wavelength of the optical radiation emitted by the system subject of the present invention, the normalized electric field being calculated by multiple finite element numerical simulations for the SARS-COV2 virus model of FIG. 3. [Figure 5] Figure 5 is a perspective view of a coronavirus family virus model for numerical simulations. [Figure 6] FIG. 6 is a perspective view with transparency of a virus model of rotavirus for numerical simulation. [Figure 7] FIG. 7 is a perspective view with transparency of a Picornaviridae virus model for numerical simulations. [Figure 8] FIG. 8 is a perspective view of a virus model of the Herpesviridae family for numerical simulation. [Figure 9] FIG. 9 is a perspective view with transparency of the HIV virus model for numerical simulations. [Figure 10A] 10A and 10B are perspective views of a first smallpox virus model for numerical simulation and a second smallpox virus model for numerical simulation, respectively, where the second virus model has different dimensions than the first model. [Figure 10B] Figure 10B is a perspective view of a first smallpox virus model for numerical simulation and a perspective view of a second smallpox virus model for numerical simulation, respectively, where the second virus model has different dimensions than the first model. [Figure 11] FIG. 11 is a perspective view of an HBV virus model for numerical simulation. [Figure 12] FIG. 12 is a perspective view with transparency of an Orthomyxoviridae virus model for numerical simulations. [Figure 13] FIG. 13 is a perspective view of an adenovirus virus model for numerical simulation. [Figure 14] FIG. 14 is a perspective view of an HCV virus model for numerical simulation. [Figure 15A] FIG. 1 is a perspective view of a first model variant of respiratory syncytial virus RSV for numerical simulations. [Figure 15B] FIG. 1 is a perspective view of a second model variant of respiratory syncytial virus RSV for numerical simulations. [Figure 15C] FIG. 1 is a perspective view of a third model variant of respiratory syncytial virus RSV for numerical simulations. [Figure 15D] FIG. 1 is a perspective view of a fourth model variant of respiratory syncytial virus RSV for numerical simulations. [Figure 15E] FIG. 1 is a perspective view of a fifth model variant of respiratory syncytial virus RSV for numerical simulations. [Figure 15F]FIG. 1 is a perspective view of a sixth model variant of respiratory syncytial virus RSV for numerical simulations. [Figure 15G] FIG. 1 is a perspective view of a seventh model variant of respiratory syncytial virus RSV for numerical simulations. [Figure 16] FIG. 1 is a perspective view of E. coli for numerical simulation. [Figure 17] FIG. 1 is a perspective view of Salmonella for numerical simulation. [Figure 18] FIG. 1 is a perspective view of a botulinum specimen for numerical simulation. DETAILED DESCRIPTION OF THE INVENTION
[0044] Referring to Figure 1, a system for producing light radiation to neutralize microorganisms, particularly the SARS COV-2 coronavirus.
[0045] The system comprises: a light source 1 for emitting optical radiation; storage means 2 in which the following are stored: one or more unique identification codes, each associated with a respective microorganism; and at least one respective wavelength range associated with said microorganism; a logic control unit 3 connected to said light source 1 and to said storage means 2, selecting a wavelength range based on the microorganism to be neutralized; activating said light source 1 so that the optical radiation emitted by said light source 1 has a wavelength within said selected wavelength range, such that, when the system is in use, said optical radiation induces optical resonance in microorganisms, causing alteration of the genetic properties of said microorganisms; and a logic control unit 3 configured to perform the following.
[0046] Regarding the light source 1, the light source may be a UV lamp or a LED light source or a laser.
[0047] In particular, the wavelength ranges have been previously identified for each microorganism so as to induce optical resonance phenomena within the microorganism, as better disclosed below.
[0048] Multiple wavelength ranges can be associated with one or more microorganisms.
[0049] Wavelength values in this wavelength range are chosen to induce optical resonance within the microorganism.
[0050] When multiple wavelength ranges are associated with one microorganism, the logic control unit 3 may be configured to select a wavelength range from among the multiple wavelength ranges.
[0051] Preferably, the logic control unit is configured to select a wavelength range whose wavelength value is greater than wavelength values belonging to other wavelength ranges of said plurality of wavelengths.
[0052] In fact, light radiation with higher wavelength values may belong to the visible spectrum rather than the ultraviolet spectrum.
[0053] Therefore, the light radiation emitted to the microorganisms is not harmful to human tissue.
[0054] It is preferred that the light source 1 is an LED light source, since an LED light source can emit light radiation with a narrower bandwidth and a more limited angle of emission than the light radiation emitted by a UV lamp.
[0055] Preferably, the bandwidth is 4 nm or less, and more preferably, the bandwidth is between 1 nm and 3 nm.
[0056] Advantageously, the use of narrow bandwidths, particularly between 1 and 3 nm, makes it possible to ensure, on the one hand, that the total dose of optical radiation to which the patient is exposed is below safety limits, and, on the other hand, that the microorganisms are irradiated with optical radiation having a wavelength that induces said optical resonance.
[0057] For light radiation emitted by an LED light source, the bandwidth and limited emission angle are useful for having light radiation that can have greater sterilizing or purifying capabilities.
[0058] In particular, the fact that optical radiation has a limited angle of emission allows it to maintain a high power density even at significant distances from the source.
[0059] Furthermore, LED light sources consume less energy than UV lamps to emit light radiation with the same intensity.
[0060] From the viewpoint of energy, it is more preferable that the light source 1 is a laser.
[0061] Therefore, lasers can be used to efficiently neutralize microorganisms belonging to a genus of viruses called the Coronaviridae family, such as the SARS-Cov-2 coronavirus.
[0062] The system may include at least one optical device 4 for focusing the optical radiation emitted by the light source 1 onto human tissue or onto an object to be sterilized or disinfected.
[0063] The optical device 4 is connected to the light source 1 through at least one first optical fiber.
[0064] The optical device 4 may include one or more lenses.
[0065] The one or more lenses may be converging to reduce the diameter of the optical radiation emitted by the light source 1 or diverging to increase the diameter of the optical radiation emitted by the light source 1 .
[0066] The system may include multiple optical devices, even if different from each other, depending on the type of light source.
[0067] The system may include filtering means 5 for selecting a predetermined bandwidth to obtain an optical resonance in the microorganism.
[0068] The filtering means is necessary when the light source is a UV lamp or an LED light source, but the presence of the filtering means is not necessary when the light source is a laser.
[0069] The filtering means 5 may include a bandpass filter.
[0070] In the disclosed embodiment, the optical device 4 is arranged between the light source 1 and the filtering means 5 .
[0071] However, the filtering means 5 can be located elsewhere.
[0072] For example, the filtering means 5 may be included in the optical device 4 without departing from the scope of the present invention.
[0073] In practice, the light source 1 may be capable of emitting optical radiation having a broadband spectrum comprising a plurality of wavelengths, and the filtering means 5 may comprise or consist of a bandpass filter configured to only allow wavelengths within the wavelength range to pass.
[0074] As already mentioned, the bandwidth of the wavelength range is preferably 4 nm or less, more preferably between 1 nm and 3 nm.
[0075] The system may include an optical probe 6 .
[0076] The optical probe 6 can be connected to the filtering means 5 if the filtering means 5 is included in the system, or to the optical device 4 if the filtering means 5 is not included in the system (e.g. when the light source is a laser).
[0077] In particular, the optical probe 6 can be connected to the filtering means 5 or to the optical device 4 via a second optical cable.
[0078] In a variant, the optical radiation 1 can be included in the optical probe 6 .
[0079] The optical probe may be a bronchoscopic probe, or a laryngeal probe, or a gastroesophageal probe, or an endoscopic probe.
[0080] Regardless of the type of probe described above, the optical probe 6 may be inserted during use in a patient, for example, within the airway, esophagus, hollow organs, and / or blood vessels.
[0081] Regardless of the presence of the optical probe 6 , the system may include a user interface module 7 .
[0082] The user interface module 7 may include a display device 7A for displaying the optical radiation and one or more parameters associated with the optical radiation, such as wavelength, optical power, duration of irradiation, etc.
[0083] The above-described system can be included in a dialysis machine.
[0084] Generally, a hemodialysis machine includes: at least one dialyzer filter, and - A fluid circuit connected to a first vascular access point of a patient and to a second vascular access point different from the first vascular access point (e.g., the two vascular access points may be located in an arteriovenous fistula).
[0085] Through the fluid circuit, a volume of blood is drawn from a first vascular access point and pumped towards the dialyzer filter.
[0086] The dialyzer filter filters the volume of blood before it is returned to the patient through the fluid circuit at a second vascular access point.
[0087] If a dialysis machine includes the system, the light source 1 is installed in the dialyzer filter so that the patient's blood is illuminated before, during or after filtration.
[0088] Below are some examples of genera of microorganisms and wavelengths of optical radiation (expressed in nanometers) that may be used to neutralize such microorganisms:
[0089] The wavelengths were identified through modeling of the microorganism and simulation of the system using numerical simulation software to solve one or more differential equations for the electromagnetic fields associated with the optical radiation received by the microorganism.
[0090] In other words, the numerical simulation simulates the propagation of optical radiation in a 3D model of at least one microorganism belonging to a given genus of microorganisms in an environment.
[0091] Each microorganism was modeled using the mean size.
[0092] The results of the numerical simulation are applicable to microorganisms with dimensions similar to those of the microbial subjects of the numerical simulation.
[0093] In particular, these dimensions may vary by a factor of ±5% relative to the size of the microorganisms being simulated.
[0094] Therefore, the results of the numerical simulations for approximately spherical microorganisms with an outer diameter equal to 100 nm can be applied to microorganisms with dimensions between 95 nm and 105 nm.
[0095] To model the behavior of microorganisms in air or water, the environment was modeled as a volume in which the physical properties of air or water were larger than the size of the associated microorganisms.
[0096] If we model a virus with an outer diameter equal to 100 nm, this environment would be, for example, 800 x 800 x 800 nm 3 It may be a cube with dimensions equal to
[0097] When the microorganism is a virus, it is particularly advantageous to model its behavior in water, since viruses are typically carried in fluids, such as saliva droplets.
[0098] Referring to Figure 5B, for 3D modeling of a virus belonging to the genus known as "Coronavirus family," specifically SARS-COV-2, such a virus was modeled using two concentric spherical elements, a first spherical element having a first diameter and a second spherical element having a second diameter smaller than the first diameter, to define four separate regions of the virus.
[0099] In particular, the shell of said first spherical element represents a first region of the virus associated with the pericapsid, said first diameter being between 95 nm and 105 nm, and in a particular case equal to 100 nm.
[0100] The shell of said second spherical element represents the second region of the virus associated with the capsid and has a diameter between 85.5 nm and 94.5 nm, and in a particular case a diameter equal to 90 nm.
[0101] Indeed, each shell is associated with a membrane of the microorganism and is assumed to have a thickness of 5 nm.
[0102] This assumption was also applied to further simulated viral membrane models, as better shown below.
[0103] The third region of the virus is between the shell of the first spherical element and the shell of the second spherical element, and the fourth region of the virus is inside the second spherical element and is associated with the genetic material, in this case viral RNA.
[0104] Furthermore, the first spherical element contains 100 protrusions, each with a length equal to 20 nm, to model the spikes of SARS-COV2.
[0105] These spikes were modeled as additional regions.
[0106] Other microorganisms can be modeled using 3D models other than those described above, particularly for viruses that contain several membranes, where the 3D models can provide a greater number of regions than those described above.
[0107] As mentioned above, the SARS-COV-2 virus is modeled through multiple concentric elements with spherical shapes.
[0108] However, a microorganism can be modeled with one or more elements having an ellipsoid shape, as explained below.
[0109] Each region of the virus is associated with a certain physical property, in particular a respective refractive index of electromagnetic radiation.
[0110] For SARS-COV2 and all other simulated viruses (explained better below), the refractive indices used are: - Refractive index of each virus membrane: 1.1+j0.001; - Refractive index of genetic material: 1.53+j1.1E-7; - Refractive index of virus matrix: 1.37+j1.1E-7, e; - Refractive index of spike protein: 1.47+j0.00274.
[0111] The differential equations were solved using the software for numerical simulation.
[0112] In the described embodiment, the software is finite element software, in particular Cosmol Multiphysics®, more particularly Cosmol Multiphysics® 5.5.
[0113] The Helmholtz equation for the electromagnetic field was solved in the frequency or time domain starting from closed boundary conditions to simulate the propagation of optical radiation of microorganisms inserted in the environment.
[0114] In particular, since the purpose of the numerical simulation is to observe the frequency behavior of microorganisms exposed to optical radiation having a predetermined wavelength, this equation was solved in the frequency domain to reduce the number of calculations required to process the data obtained from the numerical simulation.
[0115] For each simulation, the presence of an electromagnetic field source with a given wavelength and the fact that the radio waves were plane waves were used as boundary conditions.
[0116] The electromagnetic field source was placed at an infinite distance from the modeled microorganism, such that the wavefront impacting this microorganism was assumed to be locally flat.
[0117] In other words, the light source is positioned at an infinite distance from the microorganisms and emits light radiation having said predetermined wavelength.
[0118] Furthermore, the "perfectly matched layer" condition was used to model the behavior of the outer surface of the cube, which represents the environment into which the microorganisms are inserted.
[0119] The condition requires complete absorption of optical radiation incident on the outer surface of the cube at any angle of incidence.
[0120] The software for numerical simulations made it possible to carry out a frequency / wavelength scan of the light radiation to identify the frequency / wavelength at which the light intensity inside the microorganism had a relative maximum.
[0121] With reference to Figures 3 and 5 to 18, the results of simulations performed on viruses or bacteria belonging to the most common genera are shown below.
[0122] Figures 3, 5, 6, 7, 8, 9, 10A, 10B, 11, 12, 13, 14, 15A, 15B, 15C, 15D, 15E, 15F, 16, 17, and 18 show models of viruses or bacteria, respectively, that are used to simulate optical radiation incident on such viruses or bacteria.
[0123] Referring to the virus genus called "Coronavirus family", the SARS COV-2 virus shown in Figure 3 was simulated with the properties already described above.
[0124] For the virus, the table below shows the wavelength values obtained in numerical simulations at which it was possible to obtain optical resonances, and the respective values obtained from the ratio of the same wavelength values to the diameter values of the single membrane on which the virus is modeled. [Table 1]
[0125] The possible ranges of wavelengths centered around each wavelength value with a bandwidth equal to 4 nm are as follows: -first wavelength range: 158 nm to 162 nm; - second wavelength range: 111 nm to 115 nm; -Third wavelength range: 96nm~100nm.
[0126] In alternative embodiments, such a range may have a bandwidth between 1 nm and 3 nm.
[0127] A preferred wavelength value in the first wavelength range is 160 nm.
[0128] A preferred wavelength value in the second wavelength range is 113 nm.
[0129] A preferred wavelength value for the third wavelength range is 98 nm.
[0130] More preferably, the preferred wavelength value is 160 nm.
[0131] Each wavelength value corresponds to the peak of the simulated electromagnetic field Es (ie, calculated by numerical simulation) normalized with respect to the electromagnetic input field Ein.
[0132] FIG. 4 shows a portion of the simulated electromagnetic field Es normalized with respect to the input electromagnetic field Ein, in terms of wavelengths in the visible spectrum.
[0133] The normalized simulated electromagnetic field Es in FIG. 4 has multiple peaks, one at each wavelength value shown in the table above.
[0134] Below is a respective table showing, for each simulated virus / bacteria with given properties, one or more values, called wavelengths, at which the optical resonance is obtained, and for each wavelength value, at least one respective first value obtained from the ratio between the same wavelength value and the diameter of the first outer membrane at which the virus is modeled.
[0135] For membrane-bearing microorganisms, d is the diameter of the spherical element representing the membrane.
[0136] In the case of a microorganism having two membranes, d1 is the diameter of the first spherical element representing the first or outer membrane, and d2 is the diameter of the second spherical element representing the second membrane, located in the internal volume defined by the first membrane.
[0137] With further reference to the genus of viruses called "Coronavirus family," the MERS or SARS-COV virus shown in Figure 6 is modeled with the following characteristics: d = diameter of the spherical element representing the membrane = 180 nm; Number of spikes = 98, Spike length = 20 nm. [Table 2]
[0138] The number of possible wavelength ranges centered around each wavelength value with a bandwidth equal to 4 nm is as follows: -first wavelength range: 172 nm to 176 nm; - second wavelength range: 134nm~138nm; -Third wavelength range: 126nm~130nm, -Fourth wavelength range: 100nm~104nm; -fifth wavelength range: 84nm~88nm, -6th wavelength range: 72nm~76nm, -7th wavelength range: 56nm~60nm.
[0139] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0140] A preferred wavelength value in the first wavelength range is 174 nm.
[0141] A preferred wavelength value in the second wavelength range is 136 nm.
[0142] A preferred wavelength value in the third wavelength range is 128 nm.
[0143] The preferred wavelength value in the fourth wavelength range is 102 nm.
[0144] A preferred wavelength value in the fifth wavelength range is 86 nm.
[0145] A preferred wavelength value in the sixth wavelength range is 74 nm.
[0146] The preferred wavelength value in the seventh wavelength range is 58 nm.
[0147] More preferably, the preferred wavelength value is 174 nm.
[0148] With reference to the virus genus called "Reoviridae," the rotavirus shown in Figure 6 is modeled with the following characteristics: d1 = diameter of the spherical element representing the first membrane, called the supercapsid = 90 nm; d2 = diameter of the spherical element representing the second membrane called the pericapsid = 80 nm.
[0149] Furthermore, the virus has a capsid with a diameter of 30 nm.
[0150] However, the results obtained were not altered by omitting the capsid, and therefore the presence of the capsid was considered negligible for virus modeling. [Table 3]
[0151] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: -first wavelength range: 112 nm to 116 nm; - second wavelength range: 66nm~70nm; -Third wavelength range: 52nm~56nm.
[0152] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0153] The preferred wavelength value in the first wavelength range is 114 nm.
[0154] A preferred wavelength value in the second wavelength range is 68 nm.
[0155] A preferred wavelength value in the third wavelength range is 54 nm.
[0156] More preferably, the preferred wavelength value is 114 nm.
[0157] Referring to the virus genus called "Picornaviridae," the rhinovirus or aphthovirus or cardiovirus or hepatovirus or poliovirus shown in Figure 7 is modeled with the following characteristics: d = diameter of the spherical element associated with the membrane = 30 nm. [Table 4]
[0158] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 44 nm to 48 nm, Second wavelength range: 30nm~34nm.
[0159] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0160] A preferred wavelength value in the first wavelength range is 46 nm.
[0161] A preferred wavelength value for the second wavelength range is 32 nm.
[0162] More preferably, the preferred wavelength value is 46 nm.
[0163] Referring to the genus of viruses called "Herpesviridae," the human cytomegalovirus shown in Figure 8 is modeled with the following characteristics: d = diameter of the spherical element representing the membrane = 200 nm; Number of spikes: 200, Length: 20nm. [Table 5]
[0164] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 316 nm to 320 nm, Second wavelength range: 216 nm to 220 nm; Third wavelength range: 190nm~194nm; Fourth wavelength range: 165nm~169nm.
[0165] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0166] A preferred wavelength value in the first wavelength range is 318 nm.
[0167] A preferred wavelength value in the second wavelength range is 218 nm.
[0168] The preferred wavelength value in the third wavelength range is 192 nm.
[0169] The preferred wavelength value in the fourth wavelength range is 167 nm.
[0170] More preferably, the preferred wavelength value is 318 nm.
[0171] With reference to the genus of viruses called "Retroviridae," the HIV virus, shown in Figure 9, is modeled with the following characteristics: d = diameter of the spherical element representing the membrane = 100 nm. [Table 6]
[0172] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 149 nm to 153 nm; Second wavelength range: 103 nm to 107 nm; Third wavelength range: 92nm~96nm; Fourth wavelength range: 71nm~75nm.
[0173] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0174] A preferred wavelength value in the first wavelength range is 151 nm.
[0175] A preferred wavelength value in the second wavelength range is 105 nm.
[0176] The preferred wavelength value for the third wavelength range is 94 nm.
[0177] A preferred wavelength value in the fourth wavelength range is 73 nm.
[0178] More preferably, the preferred wavelength value is 151 nm.
[0179] Referring to the genus of viruses called "Poxviridae," the smallpox virus shown in Figure 10A is modeled with the following characteristics: d1 = maximum diameter of the first ellipsoid element representing the first membrane = 350 nm; d2 = maximum diameter of the second ellipsoidal element representing the second membrane, located in the internal volume defined by the first membrane = 270 nm. [Table 7]
[0180] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 515 nm to 519 nm, Second wavelength range: 345nm~349nm, Third wavelength range: 265nm~269nm, Fourth wavelength range: 214nm~218nm.
[0181] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0182] A preferred wavelength value in the first wavelength range is 517 nm.
[0183] A preferred wavelength value in the second wavelength range is 347 nm.
[0184] A preferred wavelength value in the third wavelength range is 267 nm.
[0185] The preferred wavelength value in the fourth wavelength range is 216 nm.
[0186] More preferably, the preferred wavelength value obtained by numerical simulation is 517 nm.
[0187] Referring to the genus of viruses called "Poxviridae," the smallpox virus shown in Figure 10B is modeled with the following additional characteristics: d1 = maximum diameter of the first ellipsoid element representing the first membrane = 320 nm; d2 = maximum diameter of the second ellipsoidal element representing the second membrane, located in the internal volume defined by the first membrane = 240 nm. [Table 8]
[0188] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 506 nm to 510 nm; Second wavelength range: 359nm~363nm, Third wavelength range: 296nm~300nm, Fourth wavelength range: 241nm~245nm, Fifth wavelength range: 215nm~219nm.
[0189] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0190] A preferred wavelength value in the first wavelength range is 508 nm.
[0191] A preferred wavelength value in the second wavelength range is 361 nm.
[0192] A preferred wavelength value in the third wavelength range is 298 nm.
[0193] The preferred wavelength value in the fourth wavelength range is 243 nm.
[0194] The preferred wavelength value in the fourth wavelength range is 217 nm.
[0195] More preferably, the preferred wavelength value is 508 nm.
[0196] Referring to the genus of viruses called "Hepadnaviridae," the HBV virus (also known as Hepatitis B), shown in Figure 11, is modeled with the following additional characteristics: d = diameter of the spherical element representing the membrane = 42 nm; Number of spikes = 80, Spike length = 4 nm. [Table 9]
[0197] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 67 nm to 71 nm; Second wavelength range: 38 nm to 42 nm; Third wavelength range: 29nm~33nm.
[0198] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0199] A preferred wavelength value in the first wavelength range is 69 nm.
[0200] A preferred wavelength value for the second wavelength range is 40 nm.
[0201] The preferred wavelength value for the third wavelength range is 94 nm.
[0202] More preferably, the preferred wavelength value obtained by numerical simulation is 69 nm.
[0203] With reference to the virus genus called "Orthomyxoviridae," the influenza virus shown in Figure 12 is modeled with the following additional characteristics: d = diameter of the spherical element representing the membrane = 110 nm; Number of spikes = 200, Spike length = 15 nm. [Table 10]
[0204] The possible ranges of wavelengths centered around each wavelength value with a bandwidth equal to 4 nm are as follows: First wavelength range: 170 nm to 174 nm; Second wavelength range: 119 nm to 123 nm; Third wavelength range: 104nm~108nm; Fourth wavelength range: 81nm~85nm.
[0205] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0206] A preferred wavelength value in the first wavelength range is 172 nm.
[0207] A preferred wavelength value in the second wavelength range is 121 nm.
[0208] The preferred wavelength value in the third wavelength range is 106 nm.
[0209] The preferred wavelength value in the fourth wavelength range is 83 nm.
[0210] More preferably, the preferred wavelength value is 172 nm.
[0211] With reference to the genus of viruses called "Adenoviridae," the adenovirus shown in Figure 13 is modeled with the following additional characteristics: d = diameter of the spherical element representing the membrane = 80 nm; Number of spikes = 160, Spike length = 20 nm. [Table 11]
[0212] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 120 nm to 126 nm; Second wavelength range: 85 nm to 89 nm; Third wavelength range: 75nm~79nm, Fifth wavelength range: 58nm~62nm.
[0213] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0214] A preferred wavelength value in the first wavelength range is 124 nm.
[0215] A preferred wavelength value in the second wavelength range is 87 nm.
[0216] A preferred wavelength value in the third wavelength range is 77 nm.
[0217] A preferred wavelength value for the fourth wavelength range is 60 nm.
[0218] More preferably, the preferred wavelength value is 124 nm.
[0219] Referring to the genus of viruses called "Flaviviridae," the HCV virus (also known as Hepatitis C), shown in Figure 14, is modeled with the following additional characteristics: d = diameter of the spherical element representing the membrane = 50 nm. [Table 12]
[0220] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 77 nm to 81 nm, Second wavelength range: 49 nm to 53 nm; Third wavelength range: 38nm~42nm, Fourth wavelength range: 34nm~38nm.
[0221] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0222] A preferred wavelength value in the first wavelength range is 79 nm.
[0223] A preferred wavelength value in the second wavelength range is 51 nm.
[0224] A preferred wavelength value for the third wavelength range is 40 nm.
[0225] The preferred wavelength value for the fourth wavelength range is 36 nm.
[0226] More preferably, the preferred wavelength value is 79 nm.
[0227] With reference to the virus genus called "Paramyxoviridae" and the subfamily called "Pneumoviridae," the respiratory syncytial virus shown in Figure 15A is modeled with the following characteristics: d = diameter of the spherical element representing the membrane = 50 nm; Number of spikes: 22. [Table 13]
[0228] The possible ranges of wavelengths centered around each wavelength value with a bandwidth equal to 4 nm are as follows: First wavelength range: 98 nm to 102 nm; Second wavelength range: 68nm~72nm, Third wavelength range: 59nm~63nm, Fourth wavelength range: 52nm~56nm.
[0229] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0230] A preferred wavelength value for the first wavelength range is 100 nm.
[0231] A preferred wavelength value for the second wavelength range is 70 nm.
[0232] A preferred wavelength value in the third wavelength range is 61 nm.
[0233] The preferred wavelength value in the fourth wavelength range is 54 nm.
[0234] More preferably, the preferred wavelength value is 100 nm.
[0235] With reference to the virus genus called "Paramyxoviridae" and the subfamily called "Pneumoviridae," the respiratory syncytial virus shown in Figure 15B is modeled with the following characteristics: d = diameter of the spherical element representing the membrane = 130 nm; Number of spikes: 40. [Table 14]
[0236] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 198 nm to 202 nm; Second wavelength range: 138nm~142nm, Third wavelength range: 120nm~124nm; Fourth wavelength range: 106nm~110nm.
[0237] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0238] A preferred wavelength value for the first wavelength range is 200 nm.
[0239] A preferred wavelength value in the second wavelength range is 140 nm.
[0240] A preferred wavelength value in the third wavelength range is 122 nm.
[0241] The preferred wavelength value in the fourth wavelength range is 108 nm.
[0242] More preferably, the preferred wavelength value is 200 nm.
[0243] With reference to the virus genus called "Paramyxoviridae" and the subfamily called "Pneumoviridae," the respiratory syncytial virus shown in Figure 15C is modeled with the following characteristics: d = diameter of the spherical element representing the membrane = 260 nm; Number of spikes: 80. [Table 15]
[0244] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 404 nm to 408 nm; Second wavelength range: 285nm~290nm, Third wavelength range: 242nm~247nm, Fourth wavelength range: 220nm~224nm.
[0245] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0246] A preferred wavelength value in the first wavelength range is 406 nm.
[0247] A preferred wavelength value in the second wavelength range is 287 nm.
[0248] A preferred wavelength value in the third wavelength range is 245 nm.
[0249] The preferred wavelength value in the fourth wavelength range is 222 nm.
[0250] More preferably, the preferred wavelength value is 406 nm.
[0251] With reference to the virus genus called "Paramyxoviridae" and the subfamily called "Pneumoviridae," the respiratory syncytial virus shown in Figure 15D is modeled with the following characteristics: d = diameter of the spherical element representing the membrane = 390 nm; Number of spikes: 120. [Table 16]
[0252] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 606 nm to 610 nm; Second wavelength range: 427nm~431nm, Third wavelength range: 361nm~365nm, Fourth wavelength range: 276nm~280nm.
[0253] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0254] A preferred wavelength value in the first wavelength range is 608 nm.
[0255] A preferred wavelength value in the second wavelength range is 429 nm.
[0256] A preferred wavelength value in the third wavelength range is 363 nm.
[0257] The preferred wavelength value in the fourth wavelength range is 278 nm.
[0258] More preferably, the preferred wavelength value obtained by numerical simulation is 608 nm.
[0259] With reference to the virus genus called "Paramyxoviridae" and the subfamily called "Pneumoviridae," the respiratory syncytial virus shown in Figure 15E is modeled with the following characteristics: d = diameter of the spherical element representing the membrane = 520 nm; Number of spikes: 190. [Table 17]
[0260] The possible ranges of wavelengths centered around each wavelength value with a bandwidth equal to 4 nm are as follows: First wavelength range: 814 nm to 818 nm; Second wavelength range: 576nm~580nm, Third wavelength range: 490nm~494nm, The fourth wavelength range: 448 nm to 452 nm; Fifth wavelength range: 378nm~382nm.
[0261] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0262] A preferred wavelength value in the first wavelength range is 816 nm.
[0263] A preferred wavelength value in the second wavelength range is 578 nm.
[0264] A preferred wavelength value in the third wavelength range is 492 nm.
[0265] A preferred wavelength value in the fourth wavelength range is 450 nm.
[0266] A preferred wavelength value in the fifth wavelength range is 380 nm.
[0267] More preferably, the preferred wavelength value is 816 nm.
[0268] With reference to the virus genus called "Paramyxoviridae" and the subfamily called "Pneumoviridae," the respiratory syncytial virus shown in Figure 15F is modeled with the following characteristics: d = diameter of the spherical element representing the membrane = 650 nm; Number of spikes: 240. [Table 18]
[0269] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 1017 nm to 1021 nm; Second wavelength range: 721 nm to 725 nm; Third wavelength range: 614nm~618nm; The fourth wavelength range: 560 nm to 564 nm; Fifth wavelength range: 474nm~478nm.
[0270] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0271] A preferred wavelength value in the first wavelength range is 1019 nm.
[0272] A preferred wavelength value in the second wavelength range is 723 nm.
[0273] A preferred wavelength value in the third wavelength range is 616 nm.
[0274] A preferred wavelength value in the fourth wavelength range is 562 nm.
[0275] A preferred wavelength value in the fifth wavelength range is 476 nm.
[0276] More preferably, the preferred wavelength value obtained by numerical simulation is 1019 nm.
[0277] With reference to the virus genus called "Paramyxoviridae" and the subfamily called "Pneumoviridae," the respiratory syncytial virus shown in Figure 15F is modeled with the following characteristics: d = diameter of the spherical element representing the membrane = 780 nm; Number of spikes: 280. [Table 19]
[0278] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 1222 nm to 1026 nm; Second wavelength range: 866nm~870nm, Third wavelength range: 740nm~744nm, The fourth wavelength range: 568 nm to 572 nm; Fifth wavelength range: 528nm~532nm.
[0279] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0280] A preferred wavelength value in the first wavelength range is 1224 nm.
[0281] A preferred wavelength value in the second wavelength range is 868 nm.
[0282] A preferred wavelength value in the third wavelength range is 742 nm.
[0283] A preferred wavelength value in the fourth wavelength range is 570 nm.
[0284] A preferred wavelength value in the fifth wavelength range is 530 nm.
[0285] More preferably, the preferred wavelength value obtained by numerical simulation is 1224 nm.
[0286] Referring to the genus of bacteria called "E. coli," the "E. coli" bacterium shown in FIG. 16 was modeled with the following properties: d1 = maximum diameter of the first ellipsoid element representing the first membrane = 3 μm, d2 = maximum diameter of the second ellipsoidal element representing the second membrane, located in the internal volume defined by the first membrane = 1 μm; Number of flagella: 6, Flagellum length: 3μm. [Table 20]
[0287] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 1679 nm to 1683 nm; Second wavelength range: 1153nm~1157nm, First wavelength range: 1120 nm to 1124 nm; Fourth wavelength range: 1081nm~1090nm, Fifth wavelength range: 1066nm~1070nm, The sixth wavelength range: 870 nm to 874 nm, Seventh wavelength range: 810nm~814nm, Eighth wavelength range: 779nm~783nm, 9th wavelength range: 745nm~749nm.
[0288] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0289] A preferred wavelength value in the first wavelength range is 1681 nm.
[0290] A preferred wavelength value in the second wavelength range is 1155 nm.
[0291] A preferred wavelength value in the third wavelength range is 1122 nm.
[0292] The preferred wavelength value in the fourth wavelength range is 1088 nm.
[0293] A preferred wavelength value in the fifth wavelength range is 1068 nm.
[0294] A preferred wavelength value in the sixth wavelength range is 872 nm.
[0295] The preferred wavelength value in the seventh wavelength range is 812 nm.
[0296] The preferred wavelength value in the eighth wavelength range is 781 nm.
[0297] The preferred wavelength value in the ninth wavelength range is 747 nm.
[0298] More preferably, the preferred wavelength value is 1681 nm.
[0299] Data for the simulated bacterial model are shown below: In particular, it was assumed that all bacteria have an outer membrane 50 nm thick and an inner membrane 30 nm thick, that the refractive index of the bacterial membrane is equal to 1.365 + j0.001, and that the refractive index of the cytoplasm is equal to 1.37 + j1,1E-7.
[0300] Referring to the genus of bacteria called "Salmonella," the Salmonella bacterium shown in Figure 17 is modeled with the following properties: d1 = diameter larger than the first ellipsoid element representing the first membrane = 2 μm, d2 = maximum diameter of the second ellipsoidal element representing the second membrane, located in the interior volume defined by the first membrane = 0.5 μm; Number of flagella: 10, Flagellum length: 2μm. [Table 21]
[0301] The range of possible wavelengths, centered on each wavelength value with a bandwidth equal to 4 nm, is as follows: First wavelength range: 1147 nm to 1151 nm; Second wavelength range: 1065nm~1069nm, Third wavelength range: 969nm~972nm, The fourth wavelength range: 863 nm to 867 nm; Fifth wavelength range: 773nm~777nm, The sixth wavelength range: 690 nm to 694 nm, Seventh wavelength range: 543nm~547nm.
[0302] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0303] A preferred wavelength value in the first wavelength range is 1149 nm.
[0304] A preferred wavelength value in the second wavelength range is 1067 nm.
[0305] A preferred wavelength value in the third wavelength range is 971 nm.
[0306] A preferred wavelength value in the fourth wavelength range is 865 nm.
[0307] A preferred wavelength value in the fifth wavelength range is 775 nm.
[0308] A preferred wavelength value in the sixth wavelength range is 692 nm.
[0309] The preferred wavelength value in the seventh wavelength range is 544 nm.
[0310] More preferably, the preferred wavelength value obtained by numerical simulation is 1149 nm.
[0311] Referring to the genus of bacteria called "Clothrinus botulinum," shown in FIG. 18, "Clothrinus botulinum" was modeled with the following characteristics: d1 = maximum diameter of the first ellipsoid element representing the first membrane = 5 μm; d2 = maximum diameter of the second ellipsoidal element representing the second membrane, located within the interior volume of the first membrane = 1 μm. [Table 22]
[0312] The possible ranges of wavelengths centered around each wavelength value with a bandwidth equal to 4 nm are as follows: First wavelength range: 1726 nm to 1730 nm; Second wavelength range: 1548nm~1552nm, Third wavelength range: 1418nm~1422nm; The fourth wavelength range: 1253 nm to 1257 nm; Fifth wavelength range: 1177nm~1181nm.
[0313] In alternative embodiments, such ranges may have bandwidths in the range of 1 nm and 3 nm.
[0314] A preferred wavelength value in the second wavelength range is 1728 nm.
[0315] A preferred wavelength value in the third wavelength range is 1550 nm.
[0316] A preferred wavelength value in the fourth wavelength range is 1420 nm.
[0317] A preferred wavelength value in the fifth wavelength range is 1179 nm.
[0318] More preferably, the preferred wavelength value is 1728 nm.
[0319] advantage Advantageously, as already mentioned, through the system object of the invention, in use it is possible to neutralize microorganisms using the light radiation emitted by the system.
[0320] A second advantage is given by the fact that when the system is used to neutralize microorganisms present in the human body, the light radiation emitted by this system is not harmful to the health of healthy tissue.
[0321] A further advantage is given by the fact that the system can be used to disinfect any environment or product or food or drink.
[0322] While the present invention has been described for illustrative purposes and not for limitation purposes in accordance with preferred embodiments thereof, it will be understood that those skilled in the art may make variations and / or modifications without departing from the scope thereof, as defined by the appended claims.
Claims
1. 1. A system for producing light radiation to neutralize microorganisms, comprising: a light source (1) for emitting optical radiation, one or more unique identification codes, each associated with a respective microorganism; and at least one respective wavelength range associated with the microorganism. storage means (2), a logic control unit (3) connected to said light source (1) and to said storage means (2), selecting a wavelength range based on the microorganism to be neutralized; activating the light source (1) so that the optical radiation emitted by the light source (1) has a wavelength within the selected wavelength range, such that, when the system is in use, the optical radiation induces optical resonance in the microorganisms, causing alteration of the genetic properties of the microorganisms; and the logic control unit (3) configured to perform When multiple wavelength ranges are associated with the same microorganism, the logic control unit (3) is configured to select, among the wavelength ranges from the multiple wavelength ranges, a wavelength range having a wavelength value that is greater than wavelength values belonging to other wavelength ranges from the multiple wavelength ranges.
2. The system of claim 1 , wherein the system comprises an optical probe (6).
3. the microorganism is the SARS-COV2 virus, the wavelength falls within the wavelength range between 158 nm and 162 nm; or the wavelength falls within the wavelength range between 111 nm and 115 nm; or The system of claim 1 , wherein the wavelength falls within a wavelength range between 96 nm and 100 nm.
4. the microorganism is a Mers or SARS-Cov virus, the wavelength falls within the wavelength range between 172 nm and 176 nm; or the wavelength falls within the wavelength range between 134 nm and 138 nm; or the wavelength falls within the wavelength range between 126 nm and 130 nm; or the wavelength falls within the wavelength range between 100 nm and 104 nm; or the wavelength falls within the wavelength range between 84 nm and 88 nm; or the wavelength falls within the wavelength range between 72 nm and 76 nm; or The system of claim 1 , wherein the wavelength falls within a wavelength range between 56 nm and 60 nm.
5. the microorganism is a rotavirus, the wavelength falls within the wavelength range between 112 nm and 116 nm; or the wavelength falls within the wavelength range between 66 nm and 70 nm; or The system of claim 1 , wherein the wavelength falls within a wavelength range between 52 nm and 56 nm.
6. the microorganism is a rhinovirus, aphthovirus, cardiovirus, hepatovirus, or poliovirus, the wavelength falls within the wavelength range between 44 nm and 48 nm; or The system of claim 1 , wherein the wavelength falls within a wavelength range between 30 nm and 34 nm.
7. the microorganism is human cytomegalovirus, the wavelength falls within the wavelength range between 316 nm and 320 nm; or the wavelength falls within the wavelength range between 216 nm and 220 nm; or the wavelength falls within the wavelength range between 190 nm and 194 nm; or The system of claim 1 , wherein the wavelength falls within the wavelength range of 165 nm and 169 nm.
8. the microorganism is an HIV virus, the wavelength falls within the wavelength range between 149 nm and 153 nm; or the wavelength falls within the wavelength range between 103 nm and 107 nm; or the wavelength falls within the wavelength range between 92 nm and 96 nm; or The system of claim 1 , wherein the wavelength falls within a wavelength range between 71 nm and 75 nm.
9. the microorganism is the smallpox virus, the logic control unit (3) is configured to store one or more dimensions of the smallpox virus in the storage means (2); Based on a first dimension of the smallpox virus between 332.5 nm and 367.5 nm, the wavelength falls within the wavelength range between 515 nm and 519 nm; or, the wavelength falls within the wavelength range between 345 nm and 349 nm; or, the wavelength is in the wavelength range of 265 nm and 269 nm; or, the wavelength falls within the wavelength range between 214 nm and 218 nm, or Based on the second dimension of the smallpox virus between 304 nm and 336 nm, the wavelength falls within the wavelength range between 506 nm and 510 nm; or, the wavelength falls within the wavelength range between 359 nm and 363 nm; or, the wavelength falls within the wavelength range between 296 nm and 300 nm; or, the wavelength falls within the wavelength range between 241 nm and 245 nm; or, The system of claim 1 , wherein the wavelength falls within a wavelength range between 215 nm and 219 nm.
10. the microorganism is the HBV virus, the wavelength is in the wavelength range of 67 nm and 71 nm; or the wavelength falls within the wavelength range between 38 nm and 42 nm; or The system of claim 1 , wherein the wavelength falls within a wavelength range between 29 nm and 32 nm.
11. the microorganism is an influenza virus, the wavelength falls within the wavelength range between 170 nm and 174 nm; or the wavelength falls within the wavelength range between 119 nm and 123 nm; or the wavelength falls within the wavelength range between 104 nm and 108 nm; or The system of claim 1 , wherein the wavelength falls within a wavelength range between 81 nm and 85 nm.
12. the microorganism is an adenovirus, the wavelength falls within the wavelength range between 122 nm and 126 nm; or the wavelength falls within the wavelength range between 85 nm and 89 nm; or the wavelength falls within the wavelength range between 75 nm and 79 nm; or The system of claim 1 , wherein the wavelength falls within a wavelength range between 58 nm and 62 nm.
13. the microorganism is the HCV virus, the wavelength falls within the wavelength range between 77 nm and 81 nm; or the wavelength falls within the wavelength range between 49 nm and 53 nm; or the wavelength falls within the wavelength range between 38 nm and 42 nm; or The system of claim 1 , wherein the wavelength falls within a wavelength range between 34 nm and 38 nm.
14. the microorganism is a respiratory syncytial virus, and the logic control unit (3) is configured to store one or more dimensions of the respiratory syncytial virus in the memory means (2); Based on a first dimension of the respiratory syncytial virus between 47.5 nm and 52.5 nm, the wavelength falls within the wavelength range between 98 nm and 102 nm; or, the wavelength falls within the wavelength range between 68 nm and 72 nm; or, the wavelength falls within the wavelength range between 59 nm and 63 nm; or, the wavelength falls within the wavelength range between 52 nm and 56 nm, or Based on the second dimension of the respiratory syncytial virus being between 123.5 nm and 136.5 nm, the wavelength falls within the wavelength range between 198 nm and 202 nm; or, the wavelength falls within the wavelength range between 138 nm and 142 nm; or, the wavelength falls within the wavelength range between 120 nm and 124 nm; or, the wavelength falls within the wavelength range between 106 nm and 110 nm, or Based on a third dimension of the respiratory syncytial virus between 247 nm and 273 nm, the wavelength falls within the wavelength range between 404 nm and 408 nm; or, the wavelength falls within the wavelength range between 285 nm and 289 nm; or, the wavelength falls within the wavelength range between 243 nm and 247 nm; or, the wavelength falls within the wavelength range between 220 nm and 224 nm, or Based on the fourth dimension of the respiratory syncytial virus between 370.5 nm and 409.5 nm, the wavelength falls within the wavelength range between 606 nm and 610 nm; or, the wavelength falls within the wavelength range between 427 nm and 431 nm; or, the wavelength falls within the wavelength range between 361 nm and 365 nm; or, the wavelength falls within the wavelength range between 276 nm and 280 nm, or Based on a fifth dimension of the respiratory syncytial virus between 494 nm and 546 nm, the wavelength falls within the wavelength range between 814 nm and 818 nm; or, the wavelength falls within the wavelength range between 576 nm and 580 nm; or, the wavelength falls within the wavelength range between 490 nm and 494 nm; or, the wavelength falls within the wavelength range between 448 nm and 452 nm; or, the wavelength falls within the wavelength range between 378 nm and 382 nm; Based on a sixth dimension of the respiratory syncytial virus between 617.5 nm and 682.5 nm, the wavelength falls within the wavelength range between 1017 nm and 1021 nm; or, the wavelength falls within the wavelength range between 721 nm and 725 nm; or, the wavelength falls within the wavelength range between 614 nm and 618 nm; or, the wavelength falls within the wavelength range between 560 nm and 564 nm; or, the wavelength falls within the wavelength range between 474 nm and 478 nm, or Based on a seventh dimension between 741 nm and 819 nm of the respiratory syncytial virus, the wavelength falls within the wavelength range between 1222 nm and 1226 nm; or, the wavelength falls within the wavelength range between 866 nm and 870 nm; or, the wavelength falls within the wavelength range between 740 nm and 744 nm; or, the wavelength falls within the wavelength range between 568 nm and 572 nm; or, The system of claim 1 , wherein the wavelength falls within a wavelength range between 528 nm and 532 nm.
15. the microorganism is Escherichia coli, the wavelength falls within the wavelength range between 1679 nm and 1683 nm; or the wavelength falls within the wavelength range between 1153 nm and 1157 nm; or the wavelength falls within the wavelength range between 1120 nm and 1124 nm; or the wavelength falls within the wavelength range between 1086 nm and 1090 nm; or the wavelength falls within the wavelength range between 1066 nm and 1070 nm; or the wavelength falls within the wavelength range between 870 nm and 874 nm; or the wavelength falls within the wavelength range between 810 nm and 814 nm; or the wavelength falls within the wavelength range between 779 nm and 783 nm; or The system of claim 1 , wherein the wavelength falls within a wavelength range between 745 nm and 749 nm.
16. the microorganism is Salmonella; the wavelength falls within the wavelength range between 1147 nm and 1151 nm; or the wavelength falls within the wavelength range between 1065 nm and 1069 nm; or the wavelength is in the wavelength range of 969 nm and 973 nm; or the wavelength falls within the wavelength range between 863 nm and 867 nm; or the wavelength falls within the wavelength range between 773 nm and 777 nm; or the wavelength falls within the wavelength range between 690 nm and 694 nm; or The system of claim 1 , wherein the wavelength falls within a wavelength range between 542 nm and 546 nm.
17. the microorganism is Clostridium botulinum, the wavelength falls within the wavelength range between 1726 nm and 1730 nm; or the wavelength falls within the wavelength range between 1548 nm and 1552 nm; or the wavelength falls within the wavelength range between 1418 nm and 1422 nm; or the wavelength falls within the wavelength range between 1253 nm and 1257 nm; or The system of claim 1 , wherein the wavelength falls within a wavelength range between 1177 nm and 1181 nm.
18. the light source is a UV lamp or an LED light source; 2. The system of claim 1, wherein the system comprises filtering means (5) for filtering the optical radiation, the filtering means comprising a bandpass filter for filtering the optical radiation so that the optical radiation has a predetermined bandwidth.
19. 19. The system according to claim 18, wherein the system comprises an optical device (4) arranged between the light source (1) and the filtering means (5).
20. 19. The system according to claim 18, wherein the system comprises an optical device (4), and the filtering means (5) are arranged inside the optical device (4).
21. 21. The system according to claim 19 or 20, wherein the optical device (4) comprises at least one lens for reducing the diameter of the optical radiation emitted by the light source (1) or at least one diverging lens for increasing the diameter of the optical radiation emitted by the light source (1).
22. 3. The system according to claim 2, wherein the optical probe (6) is a bronchoscopic probe, or a laryngeal probe, or a gastroesophageal probe, or an endoscopic probe.
23. 2. A hemodialysis machine comprising a dialyzer filter, a fluid circuit for drawing a volume of blood from a first vascular access point and for pumping said volume of blood through said filter, and the system according to claim 1, wherein said light source (1) is positioned corresponding to said dialyzer filter.
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