Insecticide for food pests

Abstract

To provide an insect repellent for food that can be safely used in general households and is sufficiently effective against pests for food such as grains.SOLUTION: An insect repellent for food comprises bicyclo[2.2.1]heptan-2-ol as an active ingredient.SELECTED DRAWING: Figure 1

Description

Technical Field

[0001] The present invention relates to a food insect repellent used when storing foods such as grains like rice and dried foods like bonito flakes, and more particularly, to a food insect repellent that can be easily used even in ordinary households, has a weak odor, and is safe for the human body.

Background Art

[0002] Conventionally, there has been a problem that pests such as rice weevils, cigarette beetles, and angoumois grain moths breed in foods such as grains like rice, wheat, barley, and beans, dried foods such as pasta, dried small fish, bonito flakes, kelp, and gourd shavings (hereinafter referred to as "grains") and damage the grains.

[0003] In recent years, various insect repellents that can easily prevent damage by grain pests have been proposed even for ordinary households. For example, insect repellents for rice using wasabi, mustard, ginger, pepper, garlic, etc. are commercially available.

[0004] Furthermore, the applicant has developed a grain and dry goods insect repellent containing one or more compounds selected from caryophyllene, eugenol, methyl chavicol, methyl cinnamate, and p-cymene as active ingredients (Patent Document 1), a grain and dry goods insect repellent containing one or more terpene compounds as active ingredients (Patent Document 2), a grain and dry goods insect repellent containing one or more essential oils obtained from sage, rosemary, basil, caraway, eucalyptus, citronella, anise, orange, or lavender as active ingredients (Patent Document 3), and charcoal The authors have proposed various insect repellents for grains and dried goods, including one or more alcohols with prime numbers 1 to 10 as active ingredients (Patent Document 4), one or more extracts or essential oils of nutmeg, anise star, cinnamon, lemongrass, or cumin, or cumin aldehyde or 1,8-cineole as active ingredients (Patent Document 5), one or more insect repellents for grains and dried goods containing green chili pepper as an active ingredient (Patent Document 6), and one or more insect repellents for grains and dried goods containing burdock root or processed burdock root as an active ingredient (Patent Document 7). [Prior art documents] [Patent Documents]

[0005] [Patent Document 1] Japanese Patent Publication No. 2005-97165 [Patent Document 2] Japanese Patent Publication No. 2005-82502 [Patent Document 3] Japanese Patent Publication No. 2004-182704 [Patent Document 4] Japanese Patent Publication No. 2004-175745 [Patent Document 5] Japanese Patent Publication No. 2012-31105 [Patent Document 6] Japanese Patent Publication No. 2013-249271 [Patent Document 7] Japanese Patent Publication No. 2016-108311 [Overview of the project] [Problems that the invention aims to solve]

[0006] Therefore, the present invention aims to develop a food pest repellent that can be used in ordinary households, is safe, and has sufficient insecticidal efficacy against food pests such as grains. [Means for solving the problem]

[0007] In order to solve the above problems, the inventors conducted diligent research and discovered that a specific compound has excellent insecticidal efficacy against food pests, leading to the present invention.

[0008] In other words, the present invention provides an insecticide for food pests containing bicyclo[2.2.1]heptan-2-ol as an active ingredient.

[0009] Furthermore, the present invention provides a method for controlling food pests, characterized by applying the above-mentioned food pest repellent to food. [Effects of the Invention]

[0010] According to the present invention, it is possible to prevent insect infestation by having a repellent effect on adult insects that breed in food products such as grains. [Brief explanation of the drawing]

[0011] [Figure 1] This is a schematic diagram of the test apparatus used for the insect control test. [Modes for carrying out the invention]

[0012] The active ingredient of the insect repellent for food pests of the present invention (hereinafter referred to as "the insect repellent of the present invention") is bicyclo[2.2.1]heptan-2-ol. This bicyclo[2.2.1]heptan-2-ol is a compound also called norborneol. As shown by the following formula, there are two kinds of optical isomers, exo-norborneol (1) and endo-norborneol (2), which are solids at normal temperature and white powder crystals. Any of these optical isomers may be used, but exo-norborneol is preferred. Also, bicyclo[2.2.1]heptan-2-ol has a very weak aroma like camphor and camphor.

[0013]

Chemical formula

Chemical formula

[0014] The above bicyclo[2.2.1]heptan-2-ol is contained in, for example, citronella oil (Poaceae Cymbopogon nardus: scientific name Cymbopogon nardus) essential oil, etc. Since citronella oil is commercially available, these essential oils can be used as they are, or essential oils can be obtained from citronella by known methods, or bicyclo[2.2.1]heptan-2-ol can be isolated from the essential oils by known methods and used. Also, since chemically synthesized bicyclo[2.2.1]heptan-2-ol is also commercially available, this can be used, or those chemically synthesized by known methods can be used.

[0015] The insect repellent of the present invention only needs to contain bicyclo[2.2.1]heptan-2-ol as an active ingredient, and the content in the insect repellent is not particularly limited. For example, it is 0.1% by mass (hereinafter simply referred to as "%") or more, preferably 0.5 to 10%, more preferably 1 to 5%.

[0016] For the insect repellent of the present invention, it is preferable from the viewpoint of effectiveness to further incorporate other food pest control components. Examples of such food pest control components include, for example, capsicum extract, wasabi extract, perilla extract, allicin, capsaicin, perillaldehyde, thyme, cardamom, nutmeg, clove, coriander, nutmeg, star anise, cinnamon, lemongrass, cumin, chili pepper, cumin aldehyde, caryophyllene, eugenol, methyl chavicol, methyl cinnamate, p-cymene, sage, rosemary, basil, caraway, eucalyptus, citronella, anise, orange, alcohols having 1 to 10 carbon atoms, geraniol, citronellol, terpineol, nerol, fenchyl alcohol, borneol, linalool, citronellal, cineol, fenchyl acetate, terpinyl acetate, bornyl acetate, linalyl acetate, camphor, α-terpinene, ocimene, camphene, terpinolene, myrcene, limonene, α-pinene, β-pinene, 1,8-cineol and other terpene compounds and other cereal pest control components. These can be incorporated singly or in combination of two or more.

[0017] In addition to other food pest control components, other optional components can be incorporated into the insect repellent of the present invention. Examples of such optional components include, for example, fragrances, deodorants, fungicides, dyes, pigments, antioxidants, ultraviolet absorbers and the like. These optional components can be incorporated singly or in combination of two or more.

[0018] Since bicyclo[2.2.1]heptan-2-ol is commonly used in fragrances, the insect repellent of the present invention can be prepared as an insect repellent for food pests formulated as a blended fragrance in combination with other fragrance components. Further, the insect repellent of the present invention can be prepared by formulating it in a conventional manner in combination with a suitable carrier if necessary. All of the insect repellents of the present invention are highly safe for the human body.

[0019] In preparing the insect repellent of the present invention, bicyclo[2.2.1]heptan-2-ol may be used as is, or it may be used after being dissolved in a solvent or surfactant as appropriate. Furthermore, in preparing the insect repellent of the present invention, bicyclo[2.2.1]heptan-2-ol may be supported on a suitable carrier.

[0020] Solvents used to dissolve bicyclo[2.2.1]heptan-2-ol include, for example, water and organic solvents. Examples of organic solvents include linear hydrocarbon compounds such as hexane, heptane, octane, decane, and paraffin; aromatic hydrocarbon compounds such as benzene, toluene, xylene, ethylbenzene, cumene, cymene, and styrene; terpene hydrocarbon compounds such as limonene, menthane, pinene, and dipentene; methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, 2-butanol, 2-methyl-1-propanol, 2-methyl-2-propanol, pentanol, hexanol, heptanol, and octano Hydrocarbon alcohols such as chloroform, carbon tetrachloride, trichloroethane, tetrachloroethane, trichloroethylene, tetrachloroethylene, chlorobenzene, dichlorobenzene, trichlorobenzene, ethyl bromide, propyl bromide, bromobenzene, dibromobenzene, fluorobenzene, etc. Fluorocarbon compounds, phenols such as phenol, cresol, xylenol, and other phenolic compounds, ether compounds such as diethyl ether, dipropyl ether, dibutyl ether, ethyl vinyl ether, anisole, phenetole, dibenzyl ether, dioxane, trioxane, furan, cineole, diethylene glycol diethyl ether, acetal, and other ether compounds, ketone compounds such as acetone, methyl ethyl ketone, 2-hexanone, cyclohexanone, fatty acid compounds such as formic acid, acetic acid, propionic acid, butyric acid, valeric acid, oleic acid, acetic anhydride, formic acid esters, acetic acid esters, propionic acid esters, butyric acid esters, valeric acid esters, heptyl acid esters, heptene carboxylic acid esters, octenic acid esters, lauric acid esters, myristic acid esters, benzoic acid esters, phenyl acetate esters, cinnamic acid esters, phthalic acid esters, salicylic acid esters, anisic acid esters, anthranilic acid esters, methyl anthranilic acid esters, chrysanthemum acid esters and other ester compounds, nitromethane, nitroethane, nitrobenzene, acetonitrile,Examples of solvents include nitrogen compounds such as methylamine, dimethylamine, allylamine, aniline, N,N-dimethylaniline, toluidine, pyridine, quinoline, ethylenediamine, formamide, pyrrolidone, and ε-caprolactam; sulfur compounds such as carbon disulfide, dimethyl sulfide, and thiophene; glycol compounds such as ethylene glycol and propylene glycol; glycol ether compounds such as 2-methoxyethanol, 2-ethoxyethanol, 2-phenoxyethanol, 3-methyl-3-methoxybutanol, and diethylene glycol monomethyl ether; sesame oil, linoleic oil, and salad oil. These solvents may be used individually or in combination of two or more.

[0021] Examples of surfactants used to dissolve bicyclo[2.2.1]heptan-2-ol include conventionally known surfactants such as cationic surfactants, anionic surfactants, amphoteric surfactants, and nonionic surfactants. These surfactants may be used individually or in combination of two or more.

[0022] The carrier on which bicyclo[2.2.1]heptan-2-ol is supported is not particularly limited, but examples include wood, paper, cloth, nonwoven fabric, silica, talc, activated carbon, gel, zeolite, cellulose beads, ceramic, etc. Among these carriers, gel is preferred.

[0023] A preferred embodiment of the insect repellent of the present invention is one in which bicyclo[2.2.1]heptan-2-ol is gelled using a suitable gelling agent. With an insect repellent using a gelling agent, the effectiveness and the end of the effective period can be determined by visually observing the decrease (shrinkage) of the gel.

[0024] Conventional known gelling agents can be used, such as superabsorbent resins like carrageenan, gellan gum, agar, gelatin, guar gum, pectin, locust bean gum, xanthan gum, sodium alginate, and sodium acrylate; hydroxyalkylated polysaccharides like dibenzylidene-D-sorbitol and hydroxypropylated guar gum; and cellulose derivatives such as hydroxyethylcellulose and hydroxypropyl methylcellulose (HPMC). These gelling agents may be used individually or in combination of two or more, but it is preferable to use hydroxypropylated guar gum and / or hydroxypropyl methylcellulose.

[0025] A more preferred embodiment of the insect repellent of the present invention includes the following compositions. Bicyclo[2.2.1]heptan-2-ol 0.5-10%, preferably 1-5% If necessary, 0.5-10%, preferably 1-5%, of other food pest control ingredients. Gelling agent 0.1-20%, preferably 1-10% Surfactant 0.1-5%, preferably 0.5-3%, as needed. If necessary, 0.0001 to 0.1% of the dye, preferably 0.001 to 0.01%. Solvent 50-99%, preferably 80-95%

[0026] The insect repellent of the present invention, using the gelling agent described above, can be prepared by appropriately mixing each component according to conventional methods. For example, when using water and an organic solvent as solvents, the insect repellent can be prepared by mixing the gelling agent and a portion of the organic solvent, adding bicyclo[2.2.1]heptan-2-ol, water, the remainder of the organic solvent, and other components as needed, mixing, and allowing it to stand.

[0027] The insecticide obtained in this way can be used as is or in a suitable container as an insecticide for food pests. Food pests include, for example, grain and / or dried food pests such as: Coleoptera, Curculionidae: grain weevil, soybean weevil; Lepidoptera, Oriental moth: oak moth; Lepidoptera, Pyralidae: Indian meal moth, Indian meal moth, striped meal moth; Coleoptera, Flat beetle family: small flat beetle, Coleoptera, Tenebrionidae: confused flour beetle, Coleoptera, Flour beetle family: large flour beetle, Coleoptera, Slender flat beetle family: sawtooth flat beetle; and cockroaches, Blattodea genus, Blattodea family: American cockroach, Common cockroach. Examples of pests include cockroaches, Japanese cockroaches, house cockroaches, and German cockroaches, which are pests of root vegetables and processed grains; swallowtail butterflies (Papilioninae subfamily, Lepidoptera), Gifu butterflies (Papilionidae family, Lepidoptera), and Parnassius stubbendorfii, which are pests of leafy vegetables; aphids (Aphiodontoidea superfamily, Hemiptera), planthoppers (Auchenorrhynchophyllae family, Hemiptera), and fruit pests (Drosophilidae family, Drosophila melanogaster, Drosophila japonica, Drosophila japonica, Drosophila nigricans, etc.). Among these food pests, those that infest grains and / or dried goods are preferred.

[0028] In this context, "insect repellent" refers to a product that repels both the larvae and adult insects that breed in food.

[0029] The insect repellent of the present invention can prevent insect infestation by being applied to food. The method of applying the insect repellent of the present invention to food is not particularly limited, but examples include placing it in a warehouse where food is stored, or inside a storage container where food is stored, and allowing it to volatilize or fumigate naturally or forcibly, or kneading, impregnating, or supporting it in the material of a container or bag for storing food. Among these methods, the insect repellent of the present invention is preferably applied to food that is stored in a storage container.

[0030] Furthermore, the types of food are not particularly limited, but examples include grains such as rice, wheat, barley, and beans; processed grain products such as pasta, bread, soba, and udon; dried foods such as dried sardines, dried bonito flakes, wheat gluten, dried gourd strips, agar, hijiki seaweed, dried shiitake mushrooms, dried daikon radish, freeze-dried tofu, nori seaweed, wakame seaweed, dried sardines, and dried shrimp; vegetables; and fruits. Among these foods, grains and / or dried foods are preferred. [Examples]

[0031] The present invention will be described in more detail below with reference to examples, but the present invention is not limited in any way by these examples.

[0032] Example 1 Insect repellent testing of bicyclo[2.2.1]heptan-2-ol: The evaluation was performed using the test apparatus shown in Figure 1. Specifically, the test apparatus consists of a test section (shown as 2 in Figure 1) and a control section (shown as 3 in Figure 1) (both are polypropylene cylindrical containers with an inner diameter of approximately 90 mm x a depth of 110 mm and a capacity of 570 ml), connected by a passage pipe 4 (size: inner diameter 20 mm x length 450 mm, thickness 3 mm), allowing the test insects to move freely between the two sections. In addition, a Petri dish 5 with a diameter of 4.6 cm is placed in test section 2 of the test apparatus, and a Petri dish 5 of the same shape as the one placed in test section 2 is placed in control section 3. Furthermore, an air vent 9 (size 450 mm x 20 mm, covered with nylon mesh and not allowing the test insects to pass through) is formed at the top of the passage pipe 4 of the test apparatus to prevent the volatilized chemicals released in test section 2 from traveling through the passage pipe 4 to control section 3.

[0033] <Insect Repellent Testing Method> In the insect control test using the above-described test apparatus, first, the lids 8 of test section 2 and control section 3 were opened, and 2 g of brown rice 6 was placed at one end of each petri dish 5, and the devices were placed in the positions shown in Figure 1. Next, 0.1 g of bicyclo[2.2.1]heptan-2-ol (exo-norborneol: Tokyo Chemical Industry Co., Ltd.) 7, as product 1 of the present invention, was placed at the end of petri dish 5 in test section 2 opposite to the brown rice 6. Then, 10 adult rice weevils, the target pest, were placed in test section 2 and 3, for a total of 20 individuals.

[0034] Subsequently, the lids 8 of both sections were closed, and the test apparatus was left to stand at 25°C. The number of larvae in test section 2 and control section 3 was counted 60 minutes, 120 minutes, and 180 minutes after setup, and the ratio of larvae present in control section 3 to the total number of larvae introduced (repellency rate) was calculated according to the following formula.

[0035]

number

[0036] [Table 1]

[0037] As a result, it was found that bicyclo[2.2.1]heptan-2-ol repels adult rice weevils.

[0038] Example 2 Gel-type food pest repellent: Using the following formulation and following the manufacturing method, a gel-type insecticide for food pests was obtained, which was designated as Products 2 and 3 of the present invention.

[0039] (Manufacturing method) A gel-type food pest repellent was manufactured by mixing a portion of the solvent (ethanol) with a gelling agent, stirring the mixture, and then adding the remaining insect repellent components, other pest control components, surfactant, dye, water, and solvent to a container and allowing it to stand.

[0040] [Table 2]

[0041] The gel-type food pest repellents 2 and 3 of the present invention were each placed in a cylindrical container with an open top (40 mm in diameter and 80 mm in height), and then placed inside a rice storage container with a capacity of approximately 22 liters (240 mm x 410 mm x 225 mm) containing 20 kg of rice. As a result, the pest repellent remained effective in the cylindrical container for 4 months. In addition, the gel-type food pest repellents shrank over time. [Industrial applicability]

[0042] According to the present invention, a food insecticide can be obtained that can prevent pests from breeding in food by repelling them.

[0043] Furthermore, this product is safe for human use and can be easily used in ordinary households. [Explanation of Symbols]

[0044] 1. Test equipment 2.. Test area 3. Control group 4. Passageway pipes 5. Petri dish 6. Brown rice 7. The present invention 8...Lid 9.. Air vents

Claims

1. A food pest repellent containing bicyclo[2.2.1]heptan-2-ol as the active ingredient.

2. The food pest repellent according to claim 1, wherein the food is grain and / or dried matter.

3. The insect repellent for food pests according to claim 1, which is gelled with a gelling agent.

4. The insecticide for food pests according to claim 3, wherein the gelling agent is hydroxypropylated guar gum and / or hydroxypropyl methylcellulose.

5. The insecticide for food pests according to claim 1, further comprising other food pest control ingredients.

6. A method for controlling food pests, characterized by applying a food pest repellent according to any one of claims 1 to 5 to food.

7. The method for controlling food pests according to claim 6, wherein the food is grain and / or dried matter.

8. The method for controlling food pests according to claim 6, wherein the food is placed in a storage container.

Images