Water-in-oil emulsion composition

Abstract

To suppress foreign odors from the combined use of a tranexamic acid and D-pantothenyl alcohol, and to provide cosmetics that do not give stickiness and offer a moist and refreshing feeling.SOLUTION: A water-in-oil emulsion composition contains following components (A), (B) and (C), with its aqueous phase having a pH of 4-7: (A) a tranexamic acid or a derivative thereof or salts thereof; (B) D-pantothenyl alcohol; and (C) a poly(oxyethylene oxypropylene) methylpolysiloxane copolymer.SELECTED DRAWING: None

Description

Technical Field

[0001] The present invention relates to a water-in-oil type emulsion composition suitable for cosmetics.

Background Art

[0002] In skin care cosmetics, it is also required to improve the feeling during application and the after-feel on the skin. For example, it has been proposed to use a water-in-oil type emulsifier formulation to suppress stickiness (Patent Documents 1, 2, etc.), or to increase the ethanol content to give a refreshing feeling of use (Patent Document 3). In addition, in water-in-oil type emulsified cosmetics, it has also been proposed to produce a feeling of overflowing water by using a specific silicone (Patent Documents 4, 5).

[0003] Usually, skin care cosmetics are formulated with active ingredients such as whitening agents and anti-wrinkle agents, and multiple combinations of them are also made (for example, Patent Document 6). Tranexamic acid is known as a whitening agent and an anti-inflammatory agent, and D-pantothenyl alcohol is known as a whitening agent and an anti-wrinkle agent, respectively.

Prior Art Documents

Patent Documents

[0004]

Patent Document 1

Patent Document 2

Patent Document 3

Patent Document 4

Patent Document 5

Patent Document 6

Summary of the Invention

Problems to be Solved by the Invention

[0005] The inventors noticed that combining tranexamic acid derivatives and D-pantothenyl alcohol as ingredients in cosmetics can produce an unpleasant solvent-like odor, and focused on the problem that this can cause discomfort when the cosmetic is applied. The present invention aims to suppress the off-odor that occurs when tranexamic acids and D-pantothenyl alcohol are used in combination. It also aims to provide a cosmetic composition that is non-sticky and provides a fresh, clean feeling. [Means for solving the problem]

[0006] The inventors diligently conducted research to solve the above problems and conceived that in a water-in-oil emulsion composition, tranexamic acids and D-pantothenyl alcohol are contained in the aqueous phase, and that by setting the pH of the aqueous phase to a neutral range, off-odors can be suppressed. Furthermore, they conceived that by using polyoxyalkylene-modified silicone when forming the water-in-oil emulsion, a fresh and refreshing feel can be provided, thus completing the present invention.

[0007] In other words, the present invention is as follows: [1] A water-in-oil emulsion composition containing the following components (A), (B), and (C), wherein the pH of the aqueous phase is 4 to 7. (A) Tranexamic acid or its derivatives or salts thereof (B) D-Pantothenyl alcohol (C) Poly(oxyethylene / oxypropylene)methylpolysiloxane copolymer [2] The composition according to [1], wherein the content of component (A) is 0.1 to 10% by weight of the whole composition. [3] The composition according to [1] or [2], wherein the content of component (B) is 0.1 to 10% by weight of the whole composition. [4] Ingredient (C) is PEG / PPG-18 / 18 dimethicone, PEG / PPG-19 / 19 dimethicone, cetyl PEG / PPG-10 / 1 dimethicone, lauryl PEG / PP The composition according to any one of [1] to [3], wherein one or more are selected from G-18 / 18 methicone. [5] The composition according to any one of [1] to [4], wherein the content of component (C) is 0.4 to 10% by weight of the whole composition. [6] The composition according to any one of [1] to [5], wherein the weight ratio ((A+B) / C) of the total content of components (A) and (B) to the content of component (C) is 0.1 to 10. [7] The composition according to any one of [1] to [6], comprising component (D) one or more selected from citric acid, succinic acid, phosphoric acid, and salts thereof. [8] The composition according to any one of [1] to [7], further comprising component (E) a polyhydric alcohol. [9] The composition according to [8], wherein component (E) is diglycerin.

[10] The composition according to any one of [1] to [9], wherein the internal phase ratio is 50% by weight or more of the total composition.

[11] A composition according to any one of [1] to

[10] , wherein the hardness at 40℃ is 15 to 50 g.

[12] A composition according to any one of [1] to

[11] , which is a topical skin preparation. [Effects of the Invention]

[0008] The present invention provides a water-in-oil emulsion composition that allows tranexamic acids and D-pantothenyl alcohol to be used in combination while minimizing the generation of off-odors, and that provides a refreshing and invigorating feeling of water overflowing. [Modes for carrying out the invention]

[0009] The water-in-oil emulsion composition of the present invention contains the following components (A), (B), and (C). (A) Tranexamic acid or its derivatives or salts thereof (B) D-Pantothenyl Alcohol (C) Poly(oxyethylene·oxypropylene) methylpolysiloxane copolymer

[0010] (A) Tranexamic acids In the present invention, tranexamic acid or its derivative or its salt is referred to as "tranexamic acids". Tranexamic acid refers to trans-4-aminomethylcyclohexane-1-carboxylic acid. Examples of derivatives of tranexamic acid include ester forms, amide forms, etc. Examples of esters of tranexamic acid include lauryl tranexamate, cetyl tranexamate, etc., and examples of amide forms of tranexamic acid include methylamide of tranexamic acid, etc.

[0011] Also, examples of salts of tranexamic acid or its derivative include alkali metal salts such as sodium salt, potassium salt; alkaline earth metal salts such as calcium salt, magnesium salt; zinc salt; iron salt; ammonium salt; salts with basic amino acids such as arginine, histidine, lysine, ornithine; salts with amines such as monoethanolamine, diethanolamine, triethanolamine, etc.

[0012] The content of tranexamic acids in the composition of the present invention is not particularly limited, but is preferably 0.1% by weight or more, more preferably 0.5% by weight or more, and even more preferably 1.0% by weight or more with respect to the whole composition. Also, it is preferably 10% by weight or less, more preferably 5% by weight or less, and even more preferably 3% by weight or less. Also, it may be within the range of non-contradictory combinations of these upper and lower limits. By containing within such a range, it becomes easier to exhibit the effects such as anti-inflammatory (suppression of rough skin) and whitening (suppression of pigmentation) exerted by tranexamic acids.

[0013] (B) D-Pantothenyl Alcohol D-Pantothenyl alcohol is a compound represented by the following structural formula (1).

Chemical formula

[0014] D-pantothenyl alcohol is used as an ingredient in topical skin preparations such as cosmetics, and is readily available; commercially available products can be used as appropriate.

[0015] The content of D-pantothenyl alcohol in the composition of the present invention is not particularly limited, but is preferably 0.1% by weight or more, more preferably 0.5% by weight or more, and even more preferably 1.0% by weight or more, relative to the total composition. It is also preferably 10% by weight or less, more preferably 5% by weight or less, and even more preferably 3% by weight or less. Furthermore, it may be within a range of non-contradictory combinations of these upper and lower limits. By including it within this range, it becomes easier to exert the effects of D-pantothenyl alcohol, such as whitening (inhibition of pigmentation) and anti-wrinkle.

[0016] (C) Poly(oxyethylene / oxypropylene)methylpolysiloxane copolymer Poly(oxyethylene-oxypropylene)methylpolysiloxane copolymer refers to a copolymer in which some of the methyl groups of a methylpolysiloxane, which may be alkyl-modified, are substituted with polyoxyethylene and polyoxypropylene. The methylpolysiloxane chain may be linear or branched, but linear is preferred. If the methylpolysiloxane is alkyl-modified, it may be modified with a linear or branched alkyl chain having 2 to 20 carbon atoms. The average degree of polymerization of polyoxyethylene is preferably 10 to 30, more preferably 15 to 25, and even more preferably 15 to 20. The average degree of polymerization of polyoxypropylene is preferably 1 to 30, more preferably 10 to 25, and even more preferably 15 to 20. Poly(oxyethylene-oxypropylene)methylpolysiloxane copolymers may be used individually or in combination of two or more types.

[0017] Poly(oxyethylene-oxypropylene)methylpolysiloxane copolymer acts as a surfactant for forming water-in-oil emulsions. By using this surfactant, the aqueous phase can be stably formed, and the emulsion composition can be stabilized, especially when the aqueous phase ratio is high, i.e., when the aqueous phase is high. A high aqueous phase emulsion provides a more refreshing, non-sticky feel when applied to the skin. It also provides good moisturizing properties.

[0018] Poly(oxyethylene-oxypropylene)methylpolysiloxane copolymers with a low HLB are preferred, specifically those with an HLB of 1 to 4, from the viewpoint of ease of forming a high-internal-phase water-in-oil emulsion. Here, HLB (Hydrophilic-Lypophilic Balance) refers to the value calculated using Griffin's formula.

[0019] As for poly(oxyethylene-oxypropylene)methylpolysiloxane copolymers, commercially available products can be used, specifically PEG / PPG-18 / 18 dimethicone ("5200"; manufactured by Toray Dow Corning), PEG / PPG-19 / 19 dimethicone ("BY11-030"; manufactured by Toray Dow Corning), cetyl PEG / PPG-10 / 1. Dimethicone ("Abil EM-90"; Goldschmidt Chemicals), Lauryl PEG / PPG-18 / 18 Methicone ("5200 Formulation Aid"; manufactured by Toray Dow Corning), PEG / PPG-20 / 20 Dimethicone ("SH3749"; manufactured by Toray Dow Corning Silicone Co., Ltd.), PEG / PPG-30 / 10 Dimethicone ("BY25-339"; manufactured by Dow Corning), PEG / PPG-15 / 15 Dimethicone ("5330 Fluid"; manufactured by Toray Dow Corning Co., Ltd.), PEG / PPG-2 0 / 22 butyl ether dimethicone ("KF-6012"; manufactured by Shin-Etsu Chemical Co., Ltd.) is preferred, but is not limited to this. Among these, PEG / PPG-18 / 18 dimethicone, PEG / PPG-19 / 19 dimethicone, cetyl PEG / PPG-10 / 1 dimethicone, and lauryl PEG / PPG-18 / 18 methicone are particularly preferred. It can be done.

[0020] The total content of poly(oxyethylene-oxypropylene)methylpolysiloxane copolymer in the composition of the present invention is not particularly limited, but is preferably 0.4 to 10% by weight, more preferably 0.6 to 6% by weight, even more preferably 0.8 to 5% by weight, and particularly preferably 1.0 to 4% by weight relative to the total composition. Using within this range makes it easier to obtain a splashing sensation (a feeling as if water is overflowing from the aqueous phase) when applied to the skin. Furthermore, if the content is less than 0.4% by weight, it may be difficult to form a water-in-oil emulsion, and if the content is greater than 10% by weight, stickiness may occur when the composition is applied.

[0021] In the present invention, the weight ratio of the total content of components (A) and (B) to the content of component (C) ((A+B) / C) is preferably 0.1 to 10, more preferably 0.2 to 5, and even more preferably 0.5 to 3. If the area is smaller than the specified range, the composition may not provide a refreshing feeling when applied, and if it is larger, the long-term stability of the composition may be compromised.

[0022] The composition of the present invention has a water-in-oil (W / O) emulsion structure. That is, it has a structure in which the aqueous phase (W phase) is encapsulated within the oil phase (O phase). In the present invention, the aqueous phase is typically composed of water and aqueous components. Here, the aqueous components may be any components that dissolve in water at 25 to 65°C. In the present invention, the oil phase is usually composed of oily components. Here, the oily components are usually oils, but are not limited to these, and may also include components that separate from water after being suspended in water at 25-65°C and allowed to stand for 1 hour. The internal phase ratio (mass ratio of the aqueous phase) in the composition of the present invention is preferably 50% by weight or more, more preferably 60% or more, and even more preferably 70% by weight or more. The upper limit is usually 90% by weight or less. When the emulsified composition has a high internal phase ratio, it is easier to obtain a bursting, disintegrating sensation (splashing sensation) of the internal aqueous phase when used.

[0023] In the present invention, components (A) and (B) are present in the aqueous phase. By setting the pH of this aqueous phase to a neutral range, specifically 4 to 7, preferably 5 to 6.5, and more preferably 5.5 to 6, the off-odor that occurs when components (A) and (B) coexist can be suppressed. To adjust the pH of the aqueous phase, the composition of the present invention preferably contains component (D) a pH adjusting agent. Preferred pH adjusting agents include one or more selected from citric acid, succinic acid, phosphoric acid, and their salts. Examples of salts include sodium salts, potassium salts, and calcium salts. Of these, citric acid and / or sodium citrate are particularly preferred. The content of the pH adjusting agent in the composition of the present invention is not particularly limited, but is preferably 0.05 to 1% by weight, more preferably 0.1 to 0.5% by weight, even more preferably 0.1 to 0.5% by weight, and particularly preferably 1.5 to 4% by weight relative to the total composition.

[0024] The composition of the present invention is preferable if it further contains component (E) a polyhydric alcohol, as this enhances the stability of the emulsified composition. Examples of such polyhydric alcohols include glycerin, diglycerin, sugar alcohols, polyethylene glycol, 1,3-butylene glycol, propylene glycol, dipropylene glycol, isoprene glycol, 1,2-pentanediol, 2,4-hexanediol, 1,2-hexanediol, and 1,2-octanediol. Of these, glycerin, diglycerin, and sugar alcohols are more preferred, with diglycerin being particularly preferred. Examples of sugar alcohols include sorbitol, erythritol, xylitol, and maltitol.

[0025] The polyhydric alcohol content in the present invention is preferably 3 to 40% by mass, more preferably 8 to 30% by mass, and even more preferably 10 to 20% by mass, relative to the total composition. Within this range, the stability of the composition tends to improve.

[0026] The composition of the present invention preferably has an appropriate hardness in order to easily produce a splashing sensation (like water overflowing) when applied to the skin or the like. Specifically, using a digital card meter (Curdmeter MAX ME-500 manufactured by I.techno Engineering), 100 The hardness measured under the conditions of a g load, a diameter of φ20 mm, and a temperature of 40°C is preferably 15 to 50 g, more preferably 20 to 40 g, and even more preferably 25 to 30 g. If the hardness is too low, the splash effect tends to be weak, and if it is too high, the feel during use may be impaired.

[0027] The composition of the present invention creates a feeling of water overflowing when applied to the skin, providing a fresh, moisturizing sensation without stickiness, and leaving the skin feeling refreshed after application. For this reason, it is preferable to use it in the form of a topical skin preparation, and more preferably in the form of a cosmetic (including quasi-drugs).

[0028] In addition to the components described above, the cosmetic composition of the present invention may optionally contain other components commonly used in cosmetics, as long as they do not impair the effects of the present invention. Such ingredients include, for example, oils and waxes such as macadamia nut oil, avocado oil, corn oil, olive oil, rapeseed oil, sesame oil, castor oil, safflower oil, cottonseed oil, jojoba oil, coconut oil, palm oil, liquid lanolin, hydrogenated coconut oil, hydrogenated oil, Japanese wax, hydrogenated castor oil, beeswax, candelilla wax, carnauba wax, privet wax, lanolin, reduced lanolin, hard lanolin, jojoba wax; hydrocarbons such as liquid paraffin, squalane, pristane, ozokerite, paraffin, ceresin, petrolatum, and microcrystalline wax; higher fatty acids such as oleic acid, isostearic acid, lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, and undecylenic acid; cetyl alcohol, stearyl alcohol, isostearyl alcohol, behemolytic acid, and behemolytic acid. Higher alcohols such as yl alcohol, octyldodecanol, myristyl alcohol, cetostearyl alcohol, etc.; cetyl isooctanoate, isopropyl myristate, hexyldecyl isostearate, diisopropyl adipate, di-2-ethylhexyl sebatate, cetyl lactate, diisostearyl malate, ethylene glycol di-2-ethylhexanoate, neopentyl glycol dicaprate, glycerin di-2-heptylundecanoate, glycerin tri-2-ethylhexanoate, trimethylolpropane tri-2-ethylhexanoate, trimethylolpropane triisostearate, pentane erythritol tetra-2-ethylhexanoate, etc.; dimethylpolysiloxane, methylphenylpolysiloxane, diphenylpolysiloxane Oils such as silicone oils, including chain-like polysiloxanes such as san; cyclic polysiloxanes such as octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and dodecamethylcyclohexanesiloxane; modified polysiloxanes such as amino-modified polysiloxanes, polyether-modified polysiloxanes, alkyl-modified polysiloxanes, and fluorine-modified polysiloxanes;

[0029] Anionic surfactants such as fatty acid soaps (sodium laurate, sodium palmitate, etc.), potassium lauryl sulfate, and alkyl sulfate triethanolamine ether; cationic surfactants such as stearyltrimethylammonium chloride, benzalkonium chloride, and laurylamine oxide; amphoteric surfactants such as imidazoline-based surfactants (2-cocoyl-2-imidazolinium hydroxide-1-carboxyethyloxy disodium salt, etc.), betaine-based surfactants (alkyl betaine, amide betaine, sulfobetaine, etc.), and amphoteric surfactants such as acylmethyl taurine; sorbitan fatty acid esters (sorbitan monostearate, sorbitan sesquioleate, etc.), glycerin fatty acids (glyceryl monostearate, etc.), propylene glycol fatty acid esters (propylene glycol monostearate, etc.), hydrogenated castor oil derivatives, and glycerin Nonionic surfactants such as propyl ethers, POE sorbitan fatty acid esters (POE sorbitan monooleate, polyoxyethylene sorbitan monostearate, etc.), POE sorbitol fatty acid esters (POE-sorbitol monolaurate, etc.), POE glycerin fatty acid esters (POE-glycerin monoisostearate, etc.), POE fatty acid esters (polyethylene glycol monooleate, POE distearate, etc.), POE alkyl ethers (POE 2-octyldodecyl ether, etc.), POE alkylphenyl ethers (POE nonylphenyl ether, etc.), pluronic types, POE-POP alkyl ethers (POE-POP 2-decyltetradecyl ether, etc.), tetronic types, POE castor oil and hydrogenated castor oil derivatives (POE castor oil, POE hydrogenated castor oil, etc.), sucrose fatty acid esters, and alkyl glucosides;

[0030] Powders such as mica, talc, kaolin, synthetic mica, calcium carbonate, magnesium carbonate, anhydrous silicic acid (silica), aluminum oxide, and barium sulfate, which may be surface-treated; inorganic pigments such as red iron oxide, yellow iron oxide, black iron oxide, cobalt oxide, ultramarine, Prussian blue, titanium dioxide, and zinc oxide, which may be surface-treated; pearlescent agents such as titanium mica, fish scale foil, and bismuth oxychloride, which may be surface-treated; organic dyes such as Red 202, Red 228, Red 226, Yellow 4, Blue 404, Yellow 5, Red 505, Red 230, Red 223, Orange 201, Red 213, Yellow 204, Yellow 203, Blue 1, Green 201, Violet 201, and Red 204, which may be lake-formed; organic powders such as polyethylene powder, polymethyl methacrylate, nylon powder, and organopolysiloxane elastomers;

[0031] Para-aminobenzoic acid-based UV absorbers; anthranilic acid-based UV absorbers; salicylic acid-based UV absorbers; cinnamic acid-based UV absorbers; benzophenone-based UV absorbers; sugar-based UV absorbers; 2-(2'-hydroxy-5'-t-octylphenyl)benzotriazole, 4-meth UV absorbers such as xy-4'-t-butyldibenzoylmethane;

[0032] Lower alcohols such as ethanol and isopropanol; vitamin A or its derivatives, vitamin B6 hydrochloride, vitamin B6 tripalmitate, vitamin B6 dioctanoate, vitamin B2 or its derivatives, vitamin B 12 Vitamin B 15 Vitamin B compounds or their derivatives; vitamin E compounds such as α-tocopherol, β-tocopherol, γ-tocopherol, vitamin E acetate, vitamin D compounds, vitamin H, pantothenic acid, pantethine, pyrroloquinoline quinone, and other vitamins; anti-inflammatory agents such as glycyrrhizic acid derivatives, glycyrrhetinic acid derivatives, salicylic acid derivatives, hinokitiol, zinc oxide, and allantoin; wrinkle-improving agents such as retinol, ascorbic acid, tocopherol, or farnesyl acetate; various extracts (e.g., Phellodendron amurense, Coptis japonica, Lithospermum erythrorhizon, Paeonia lactiflora, Swertia japonica, Birch, Cetonia tetrandra). Examples include: ginger, loquat, carrot, aloe, mallow, iris, grape, coix seed, loofah, lily, saffron, cinnamon, ginger, St. John's wort, ononis, garlic, chili pepper, dried tangerine peel, angelica, seaweed, etc.; activators such as royal jelly, photosensitizer, and cholesterol derivatives; blood circulation promoters such as nonylic acid valenylamide, capsaicin, gingerol, and tannic acid; anti-seborrheic agents such as sulfur and thianthol; anti-inflammatory agents such as thiotaurine and hypotaurine; and water-soluble polymers such as collagen and hyaluronic acid.

[0033] In addition, various active ingredients, moisturizers, preservatives, antibacterial agents, antioxidants, antioxidant aids, etc., may be optionally added to the cosmetic composition of the present invention.

[0034] Other active ingredients besides tranexamic acid derivatives and D-pantothenyl alcohol include whitening ingredients, wrinkle-improving ingredients, anti-inflammatory ingredients, and plant and animal extracts. Whitening ingredients include 4-n-butylresorcinol, ascorbic acid glucoside, 3-O-ethyl ascorbic acid, arbutin, ellagic acid, kojic acid, linoleic acid, nicotinamide, 5,5'-dipropylbiphenyl-2,2'-diol, and 5'-adenyl disodium Examples include potassium 4-methoxysalicylate, hydroquinone, and others.

[0035] As for wrinkle-improving ingredients, there are no particular limitations as long as they are commonly used in cosmetics. Examples include sodium trifluoride isopropyl oxopropylaminocarbonylpyrrolidinecarbonylmethylpropylaminocarbonylbenzoylaminoacetate, nicotinamide, vitamin A or its derivatives (retinol, retinal, retinoic acid, tretinoin, isotretinoin, tocopherol retinoic acid, retinyl palmitate, retinyl acetate, etc.), benzyl ursolate, ursolic acid phosphate, benzyl betulinate, and benzyl acid phosphate.

[0036] Examples of anti-inflammatory components include clarinon, glabridin, glycyrrhizic acid, glycyrrhetinic acid, and pantothenyl alcohol, with glycyrrhizic acid and its salts being preferred, alkyl glycyrrhetinate and its salts, and glycyrrhetinic acid and its salts.

[0037] There are no particular limitations on the use of plant and animal-derived extracts, as long as they are commonly used in pharmaceuticals, cosmetics, food products, etc. For example, Akebia extract, Thujopsis dolabrata extract, Asparagus extract, Avocado extract, Hydrangea serrata extract, Almond extract, Arnica extract, Aloe extract, Aronia extract, Apricot extract, Ginkgo extract, Indian kino extract, Fennel extract, Aralia cordata extract, Rosehip extract, Eleutherococcus senticosus extract, Enmeisou extract, Scutellaria baicalensis extract, Phellodendron amurense extract, Coptis japonica extract, Panax ginseng extract, Hypericum perforatum extract, Lamium album extract, Orange extract, Arctium moniliforme extract, Pueraria lobata extract, Chamomile extract, Carrot extract, Artemisia capillaris extract, Licorice extract, Kiwi extract, Cucumber extract, Guava extract, Sophora flavescens extract, Gardenia extract, Sasa veitchii extract, Sophora flavescens extract, Walnut extract, Grapefruit extract, Black rice extract, Chlorella extract, Mulberry extract, Ligusticum sieboldii extract, Alpinia speciosa extract, Gentian extract, Geranium thunbergii extract, Black tea extract Su, burdock extract, rice extract, fermented rice extract, fermented rice bran extract, rice germ oil, lingonberry extract, salvia extract, soapwort extract, bamboo extract, hawthorn extract, sunflower extract, sansho pepper extract, shiitake mushroom extract, rehmannia extract, lithospermum extract, perilla extract, linden extract, meadowsweet extract, peony extract, ginger extract, calamus root extract, birch extract, horsetail extract, stevia extract, stevia extract Fermented product, Hedera helix extract, Hawthorn extract, Elderflower extract, Yarrow extract, Peppermint extract, Sage extract, Mallow extract, Cnidium officinale extract, Swertia japonica extract, Morus alba bark extract, Rhubarb extract, Soybean extract, Jujube extract, Thyme extract, Dandelion extract, Tea extract, Clove extract, Citrus unshiu peel extract, Sweet tea extract, Capsicum extract, Angelica acutiloba extract, Calendula extract, Sea urchin extract, spruce extract, Houttuynia cordata extract, tomato extract, natto extract, carrot extract, garlic extract, wild rose extract, hibiscus extract, Ophiopogon japonicus extract, lotus extract, parsley extract, birch extract, witch hazel extract, Isodon japonicus extract, cypress extract, loquat extract, coltsfoot extract, butterbur extract, Poria cocos extract, butcher's broom extract, grape extract, grape seed extract, loofah extract, safflower extract, peppermint extract, linden extract, peony extract, hop extract, pine extract, marjoram Extracts such as horse chestnut extract, skunk cabbage extract, soapberry extract, lemon balm extract, seaweed extract, peach extract, cornflower extract, eucalyptus extract, saxifrage extract, yuzu extract, lily extract, coix seed extract, mugwort extract, lavender extract, green tea extract, apple extract, rooibos tea extract, reishi mushroom extract, lettuce extract, lemon extract, forsythia extract, astragalus extract, rose extract, rosemary extract, Roman chamomile extract, royal jelly extract, and burnet extract are among the preferred extracts.

[0038] Examples of humectants include polyethylene glycol, propylene glycol, glycerin, 1,3-butylene glycol, xylitol, sorbitol, maltitol, chondroitin sulfate, hyaluronic acid, mucoitin sulfate, carotenoid acid, atelocollagen, cholesteryl-12-hydroxystearate, lactic acid, sodium lactate, bile salts, dl-pyrrolidone carboxylate, short-chain soluble collagen, diglycerin (EO)PO adduct, Rosa rugosa extract, Achillea millefolium extract, and Melilotus extract. Examples of pH adjusting agents include buffering agents such as lactate-sodium lactate, citrate-sodium citrate, and succinate-sodium succinate. Examples of preservatives include methylparaben, ethylparaben, butylparaben, and phenoxyethanol. As antibacterial agents, synthetic agents such as 1,3-butylene glycol and parahydroxybenzoic acid esters are preferred, as are natural antibacterial substances such as caprylyl glycol, glyceryl caprylate, ethylhexylglycerin, and caprylhydroxamic acid. Examples of antioxidants include tocopherols, dibutylhydroxytoluene, butylhydroxyanisole, and gallic acid esters. Examples of antioxidant auxiliary agents include phosphoric acid, citric acid, ascorbic acid, maleic acid, malonic acid, succinic acid, fumaric acid, kephalin, hexametaphosphorate, phytic acid, and ethylenediaminetetraacetic acid. [Examples]

[0039] The present invention will be described in more detail below with reference to examples, but the present invention is not limited to the following examples unless it exceeds the essence of the invention.

[0040] <Manufacturing example> The emulsified compositions for the examples and comparative examples were prepared according to the formulations shown in Table 1 below. Specifically, components A, B, and E were uniformly mixed and the pH was adjusted to 5.7 at 25°C (however, in Comparative Example 3, the pH was set to 3.09). This was heated to 75°C and gradually added to a mixture of components C and D, which had been separately heated to 75°C and uniformly mixed. The mixture was stirred to emulsify, and then cooled to room temperature to obtain a W / O type emulsified composition.

[0041] <Example Test> The following items were evaluated for each emulsified composition. (1) Splash sensation: Experienced evaluators evaluated the sensation of the internal aqueous phase bursting when an appropriate amount was applied to the arm, using the following four-point scale. The results are shown in Table 1. ◎: Feels very satisfied ○: Slightly noticeable △: I don't really feel it. ×: I don't feel it at all.

[0042] (2) Refreshing feeling: After applying an appropriate amount to the arm, experienced evaluators evaluated the refreshing feeling on the skin on the following four-point scale. The results are shown in Table 1. ◎: Feels very satisfied ○: Slightly noticeable △: I don't really feel it. ×: I don't feel it at all.

[0043] (3) Stability over time: The emulsified composition was placed in standard glass bottles and stored at 50°C for one month. After storage, the appearance was visually observed by a skilled evaluator to check for any changes from immediately after manufacture, and evaluated on the following four-point scale. The results are shown in Table 1. ◎: No change ○: Slightly changed △: Changes have occurred ×: There is a clear change.

[0044] (4) Hardness: The hardness of the emulsion composition the day after preparation was measured using a digital card meter (Curdmeter MAX ME-500, manufactured by I.techno Engineering) under the conditions of 100g load, φ20mm, and 40℃. The measurements were taken using [specified method]. The results are shown in Table 1.

[0045] (5) Odor: Experienced evaluators directly smelled the emulsified composition to assess the presence or absence of odor. An off-odor, similar to a solvent smell, was detected only in Comparative Example 3.

[0046] [Table 1] [Industrial applicability]

[0047] The present invention provides a water-in-oil emulsion composition that allows for the combined use of tranexamic acids and D-pantothenyl alcohol while minimizing the generation of off-odors, and that provides a refreshing and invigorating feel, making it highly useful in industry.

Claims

1. A water-in-oil emulsion composition containing the following components (A), (B), and (C), wherein the pH of the aqueous phase is 4 to 7. (A) Tranexamic acid or its derivatives or salts thereof (B) D-Pantothenyl alcohol (C) Poly(oxyethylene / oxypropylene)methylpolysiloxane copolymer

2. The composition according to claim 1, wherein the content of component (A) is 0.1 to 10% by weight of the entire composition.

3. The composition according to claim 1, wherein the content of component (B) is 0.1 to 10% by weight of the entire composition.

4. Ingredient (C) is PEG / PPG-18 / 18 dimethicone, PEG / PPG-19 / 19 dimethicone, cetyl PEG / PPG-10 / 1 dimethicone, lauryl PEG / PPG- The composition according to claim 1, wherein the composition is one or more selected from 18 / 18 methicone.

5. The composition according to claim 1, wherein the content of component (C) is 0.4 to 10% by weight of the entire composition.

6. The composition according to claim 1, wherein the weight ratio of the total content of components (A) and (B) to the content of component (C) ((A + B) / C) is 0.1 to 10.

7. The composition according to any one of claims 1 to 6, comprising component (D) one or more selected from citric acid, succinic acid, phosphoric acid, and salts thereof.

8. The composition according to any one of claims 1 to 6, further comprising component (E) a polyhydric alcohol.

9. The composition according to claim 8, wherein component (E) is diglycerin.

10. The composition according to any one of claims 1 to 6, wherein the internal phase ratio is 50% by weight or more of the total composition.

11. The composition according to any one of claims 1 to 6, wherein the hardness at 40°C is 15 to 50 g.

12. A composition according to any one of claims 1 to 6, which is a topical skin preparation.

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