Sample analysis cartridge and method for manufacturing the same

Abstract

To provide a specimen analysis cartridge and the like with increased liquid leakage durability.SOLUTION: A specimen analysis cartridge includes a first substrate having a microfluidic channel formed on at least one surface thereof, a second substrate arranged opposite the surface on which the microfluidic channel is formed on the first substrate, and a photocurable resin layer by which the first substrate and the second substrate are bonded together. The first and second substrates include at least one of a cyclo-olefin polymer and a cyclo-olefin copolymer.SELECTED DRAWING: Figure 1

Claims

[Claim 1] A first substrate having microchannels formed on at least one side, A second substrate is disposed opposite to the surface of the first substrate on which the microchannels are formed, The invention comprises a photocurable resin layer that adheres the first substrate and the second substrate, The first substrate and the second substrate each contain at least one of a cycloolefin polymer and a cycloolefin copolymer. The 180° peel strength between the first substrate and the second substrate is 20 N / 10 mm or more. Sample analysis cartridge. [Claim 2] The sample analysis cartridge according to claim 1, wherein the thickness of the photocurable resin layer is 1.0 μm or more and 100 μm or less. [Claim 3] The sample analysis cartridge according to claim 1, wherein the minimum channel width of the microchannel is 200 μm or less. [Claim 4] The sample analysis cartridge according to claim 1, wherein the 180° peel strength between the first substrate and the second substrate is 25 N / 10 mm or more. [Claim 5] The sample analysis cartridge according to claim 1, wherein the photocurable resin layer comprises an acrylic resin and / or a methacrylic resin. [Claim 6] The sample analysis cartridge according to claim 1, wherein the photocurable resin layer is a cured product of a photocurable resin composition comprising (a) an acrylic oligomer and / or methacrylic oligomer with a weight-average molecular weight of 2000 or more, (b) an acrylic monomer and / or methacrylic monomer, and (c) a photoradical polymerization initiator. [Claim 7] The sample analysis cartridge according to claim 6, wherein the (a) acrylic oligomer and / or methacrylic oligomer has a polyurethane skeleton. [Claim 8] A method for manufacturing a sample analysis cartridge according to any one of claims 1 to 7, The aforementioned manufacturing method is The process involves applying a photocurable resin composition to the first substrate using an inkjet method, A step of bonding the second substrate to the surface of the first substrate to which the photocurable resin composition has been applied, A manufacturing method comprising the step of irradiating the photocurable resin composition with light to form the photocurable resin layer. [Claim 9] The manufacturing method according to claim 8, wherein the viscosity of the photocurable resin composition is 1.0 mPa·s or more and less than 50 mPa·s.

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