Automatic analysis device

Abstract

To improve examination throughput by an automatic analyzer.SOLUTION: An automatic analyzer comprises a plurality of reaction tube holders, a plurality of photometry portions, a reaction tank, and a drive portion. The reaction tube holder holds a reaction tube for housing a mixed solution of a specimen and a reagent. The photometry portion is provided with respect to each of the plurality of reaction tube holders and performs photometry on the mixed solution housed in the reaction tube. The reaction tank includes the plurality of reaction tube holders and the plurality of photometry portions and conveys the reaction tube held by each of the plurality of reaction tube holders by repeating rotation and stop. The drive portion rotates the reaction tank.SELECTED DRAWING: Figure 3

Description

Technical Field

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[0001] The embodiments disclosed in this specification and the drawings relate to an automatic analyzer.

Background Art

[0002] An automatic analyzer measures the components in a sample by measuring a mixture with the sample to be measured. For example, when performing a blood coagulation analysis test on a blood sample, a disposable reaction tube is installed in a reaction tank, and the blood sample and reagent are dispensed into the installed reaction tube. Then, measurement is performed on the mixture of the blood sample and reagent dispensed into the reaction tube using a photometric port including a photometric unit. The holding unit for holding the reaction tube and the photometric port are fixed to the reaction tank, and the reaction tank is fixed within the apparatus.

[0003] In such an automatic analyzer for performing a blood coagulation analysis test, in order to improve the throughput of the test, for example, a method of increasing the number of photometric ports can be cited. However, when the number of photometric ports is increased, the mechanism for installing the disposable reaction tube in the reaction tank, the mechanism for removing the reaction tube from the reaction tank, and the mechanism for dispensing the blood sample and reagent become complicated. Also, in order to increase the photometric ports, it is necessary to enlarge the reaction tank or increase the number of reaction tanks, and as a result, the entire apparatus becomes large.

Prior Art Documents

Patent Documents

[0004]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0005] One of the problems that the embodiments disclosed herein and in the drawings aim to solve is to improve the throughput of inspections performed by automated analyzers. However, the problems that the embodiments disclosed herein and in the drawings aim to solve are not limited to the above problem. Problems corresponding to the effects of each configuration shown in the embodiments described later can also be positioned as other problems. [Means for solving the problem]

[0006] The automated analyzer according to this embodiment comprises a plurality of reaction tube holders, a plurality of photometric units, a reaction vessel, and a drive unit. The reaction tube holders hold reaction tubes containing a mixture of a sample and a reagent. A photometric unit is provided for each of the plurality of reaction tube holders and measures the mixture contained in the reaction tubes. The reaction vessel comprises a plurality of reaction tube holders and a plurality of photometric units, and transports the reaction tubes held by each of the plurality of reaction tube holders by repeatedly rotating and stopping. The drive unit rotates the reaction vessel. [Brief explanation of the drawing]

[0007] [Figure 1] Figure 1 shows the configuration of an automated analyzer according to this embodiment. [Figure 2] Figure 2 shows the analytical mechanism configuration of the automated analyzer according to this embodiment. [Figure 3] Figure 3 is a cross-sectional view showing the internal configuration of the coagulation reaction unit of the automated analyzer according to the embodiment. [Figure 4] Figure 4 is a perspective view showing the configuration of the reaction vessel of the automated analyzer according to this embodiment. [Figure 5] Figure 5 is a perspective view showing the reaction vessel shown in Figure 4 with its outer casing removed. [Figure 6] Figure 6 is a perspective view showing the configuration of the photometric port of the automated analyzer according to this embodiment. [Figure 7] Figure 7 is a magnified view of the vicinity of the photometric port in Figure 3. [Figure 8] Figure 8 is a diagram illustrating the airflow inside the reaction vessel shown in Figure 3. [Figure 9] Figure 9 is a cross-sectional view showing the internal configuration of the coagulation reaction unit of the automated analyzer according to the first modified example. [Figure 10] Figure 10 is a cross-sectional view showing the internal configuration of the coagulation reaction unit of the automated analyzer according to the second modified example. [Figure 11] Figure 11 is a cross-sectional view showing the internal configuration of the coagulation reaction unit of an automated analyzer according to the third modified example. [Modes for carrying out the invention]

[0008] The automated analyzer and embodiments of the automated analyzer will be described in detail below with reference to the drawings. In the following description, components having substantially the same function and configuration will be denoted by the same reference numerals, and redundant explanations will be given only when necessary.

[0009] (Embodiment) Figure 1 is a block diagram showing the functional configuration of the automated analyzer according to this embodiment. The automated analyzer 1 shown in Figure 1 comprises an analysis mechanism 2, an analysis circuit 3, a drive mechanism 4, an input interface 5, an output interface 6, a communication interface 7, a memory circuit 8, and a control circuit 9 (control unit). The automated analyzer 1 measures the components in a sample by measuring a mixture of the sample and the analyzer. The automated analyzer 1 of this embodiment can perform blood coagulation analysis on a blood sample using a blood sample as the sample.

[0010] Analytical apparatus 2 mixes the blood sample with the reagents used for each test item. For calibration data preparation, analytical apparatus 2 mixes a standard solution of known concentration with the reagents used for each test item. The mixture of blood sample or standard solution and reagents is kept at a constant temperature of, for example, 37°C, which is optimal for enzymatic reactions in living organisms. This allows the blood sample and reagents to react.

[0011] The analysis mechanism 2 continuously measures the optical properties of a blood sample or a mixture of a standard solution and a reagent. This measurement generates standard data, expressed, for example, transmitted light intensity or absorbance, and scattered light intensity, as well as test data.

[0012] The analysis circuit 3 is a processor that generates calibration data and analysis data regarding the coagulation of a blood sample by analyzing the standard data and the test data generated by the analysis mechanism 2. For example, the analysis circuit 3 reads an analysis program from the memory circuit 8 and analyzes the standard data and the test data according to the read analysis program.

[0013] Specifically, the analysis circuit 3 measures the coagulation process in the mixture by analyzing the test data, for example. For the analysis of a mixture to which a reagent with a strong reaction is added, the analysis circuit 3 analyzes the test data obtained by detecting transmitted light, for example. For the analysis of a mixture to which a reagent with a weak and slow reaction is added, the analysis circuit 3 analyzes the test data obtained by detecting scattered light, for example. The analysis circuit 3 obtains the change in light reception intensity regarding the blood coagulation reaction based on the test data. The analysis circuit 3 calculates information regarding the coagulation of the blood sample, such as the coagulation end point, coagulation point, and coagulation time, from the reaction curve as the change in light reception intensity.

[0014] In addition, depending on the test item, the analysis circuit 3 calculates a concentration value or the like based on the calculated coagulation time and the calibration data of the test item corresponding to the test data. The analysis circuit 3 outputs analysis data including the coagulation end point, coagulation point, coagulation time, concentration value, etc. to the control circuit 9.

[0015] The drive mechanism 4 drives the analysis mechanism 2 according to the control of the control circuit 9. The drive mechanism 4 is realized by, for example, gears, stepping motors, belt conveyors, and lead screws.

[0016] The input interface 5 is connected to the control circuit 9, converts operation instructions and various information input by the operator into electrical signals, and outputs the electrical signals to the control circuit 9. For example, the input interface 5 receives the input of analysis request information including information for identifying a sample to be analyzed and information for designating inspection items of the sample from the operator. The analysis request information may further include analysis parameters of inspection items related to the sample. Also, for example, the input interface 5 receives the input of a shutdown instruction from the operator. The input interface 5 is realized, for example, by a mouse, a keyboard, and a touch pad where instructions are input by touching the operation surface.

[0017] Note that in this specification, the input interface 5 is not limited to only those equipped with physical operation components such as a mouse, a keyboard, and a touch pad. For example, an electrical signal processing circuit that receives an electrical signal corresponding to an operation instruction input from an external input device provided separately from the automatic analyzer 1 and outputs this electrical signal to the control circuit 9 is also included in the examples of the input interface 5.

[0018] The output interface 6 is connected to the control circuit 9 and outputs the signal supplied from the control circuit 9. The output interface 6 is realized, for example, by a display circuit, a printing circuit, and an audio device. The display circuit includes, for example, a CRT display, a liquid crystal display, an organic EL display, an LED display, and a plasma display. Also, the display circuit may include a processing circuit that converts data representing the display target into a video signal and outputs the video signal to the outside. The printing circuit includes, for example, a printer. Also, the printing circuit may include an output circuit that outputs data representing the printing target to the outside. The audio device includes, for example, a speaker. Also, the audio device may include an output circuit that outputs an audio signal to the outside.

[0019] Communication interface 7 connects, for example, to the hospital network NW. Communication interface 7 communicates data with the HIS (Hospital Information System) via the hospital network NW. Alternatively, communication interface 7 may communicate data with the HIS via the Laboratory Information System (LIS) connected to the hospital network NW. In addition, communication interface 7 may receive operation instructions and various information from the operator via the hospital network NW instead of input interface 5.

[0020] The memory circuit 8 includes a recording medium readable by the processor, such as a magnetic recording medium, an optical recording medium, or a semiconductor memory. The memory circuit 8 does not necessarily have to be implemented by a single storage device. For example, the memory circuit 8 may be implemented by multiple storage devices.

[0021] Furthermore, the memory circuit 8 stores the analysis program executed by the analysis circuit 3 and the control program for realizing the functions of the control circuit 9. The program used is, for example, one that is pre-installed on a computer from a network or a non-transient computer-readable storage medium, and that enables the computer to implement each function of the control circuit 9. Note that the various types of data dealt with in this specification are typically digital data. The memory circuit 8 is an example of a storage unit.

[0022] The memory circuit 8 stores analysis request information received via the input interface 5 or the communication interface 7, and execution information set and updated by the control circuit 9. The execution information represents the progress of the analysis performed based on the analysis request information. The memory circuit 8 also stores analysis data generated by the analysis circuit 3 for each test item. The memory circuit 8 stores test orders entered by the operator or test orders received by the communication interface 7 via the hospital network NW.

[0023] The control circuit 9 is a processor that functions as the central hub of the automated analyzer 1. The control circuit 9 executes the control program stored in the memory circuit 8, thereby realizing the functions corresponding to the executed control program. The control circuit 9 may also include a memory area that stores at least a portion of the data stored in the memory circuit 8.

[0024] The control circuit 9 executes the system control function 91 by running an operation program. The control circuit 9, through the system control function 91, comprehensively controls each part of the automatic analyzer 1 based on input information, for example, input from the input interface 5. The control circuit 9 is an example of a control unit.

[0025] In this embodiment, the case in which the system control function 91 is realized by a single processor is described, but the embodiment is not limited to this. For example, the system control function 91 may be realized by combining multiple independent processors to form a control circuit, and each processor executing a control program.

[0026] In the above description, the term "processor" refers to circuits such as a CPU (central processing unit), a GPU (Graphics Processing Unit), an Application Specific Integrated Circuit (ASIC), a programmable logic device (e.g., a Simple Programmable Logic Device (SPLD)), a Complex Programmable Logic Device (CPLD), and a Field Programmable Gate Array (FPGA)). When the processor is a CPU, for example, it performs its functions by reading and executing a program stored in a memory circuit. On the other hand, when the processor is an ASIC, for example, instead of the program being stored in a memory circuit, the function is directly incorporated as a logic circuit within the processor's circuit. In this embodiment, each processor is not limited to being configured as a single circuit; multiple independent circuits may be combined to form a single processor and perform its functions. Furthermore, multiple components shown in Figure 1 may be integrated into a single processor to perform its functions. The above description of "processor" is the same in the following embodiments and modifications.

[0027] Next, we will explain the configuration of analysis mechanism 2 in detail. Figure 2 shows the configuration of the analysis mechanism 2. The analysis mechanism 2 comprises a coagulation reaction unit 21, a rack sampler 22, a reagent storage unit 23, and a reaction tube storage unit 24. The analysis mechanism 2 also comprises a sample dispensing arm 25, a first reagent dispensing arm 26, a second reagent dispensing arm 27, and a reaction tube arm 28.

[0028] The analysis mechanism 2 is driven by the drive mechanism 4 and transports the reaction tube 211 held in the annular coagulation reaction unit 21. For each analysis cycle, the analysis mechanism 2 dispenses the sample, such as a blood sample or standard solution, and reagents into the transported reaction tube 211. The coagulation reaction unit 21 may also be called a reaction disk.

[0029] In the coagulation reaction unit 21, blood coagulation is measured. The coagulation reaction unit 21 holds multiple reaction tubes 211 arranged in a ring and transports the held reaction tubes 211 along a predetermined path. The coagulation reaction unit 21 is driven by the drive mechanism 4 to alternately rotate and stop at predetermined time intervals (hereinafter referred to as the analysis cycle).

[0030] The rack sampler 22 movably supports a sample rack 221 capable of holding multiple sample containers containing samples requested for measurement. In the example shown in Figure 2, a sample rack 221 capable of holding five sample containers in parallel is shown. The rack sampler 22 transports the sample rack 221 from the input position where the sample rack 221 is placed to the sample aspiration position where the sample is aspirated by the sample dispensing probe. The sample aspiration position is located, for example, at the intersection of the rotational trajectory of the sample dispensing arm 25 and the movement trajectory of the sample rack 221.

[0031] The reagent storage room 23 cools and stores the first and second reagents. Specifically, the reagent storage room 23 cools multiple reagent containers containing the first reagent, which reacts with predetermined components contained in the standard sample and the test sample, and cools multiple reagent containers containing the second reagent, which reacts with predetermined components contained in the standard sample and the test sample. The second reagent is, for example, a reagent that forms a pair with the first reagent in a two-reagent system. The second reagent may be a reagent with the same components and the same concentration as the first reagent.

[0032] Furthermore, the reagent storage compartment 23 is covered by a removable reagent cover. Inside the reagent storage compartment 23, a reagent rack is rotatably installed. The reagent rack holds multiple reagent containers arranged in a ring shape. The reagent rack is rotated and stopped for each analysis cycle by the drive mechanism 4.

[0033] A first reagent aspiration position and a second reagent aspiration position are set at predetermined locations on the reagent storage unit 23. The first reagent aspiration position is set at a location where, for example, the rotational trajectory of the first reagent dispensing arm 26 intersects with the movement trajectory of the opening of the reagent container that holds the first reagent. The second reagent aspiration position is set at a location where, for example, the rotational trajectory of the second reagent dispensing arm 27 intersects with the movement trajectory of the opening of the reagent container that holds the second reagent.

[0034] The reaction tube storage section 24 houses a plurality of reaction tubes 211. The reaction tubes 211 are made of, for example, glass, polypropylene (PP), or acrylic. The reaction tubes 211 may also be called cuvettes or reaction vessels.

[0035] The sample dispensing arm 25 is located between the coagulation reaction unit 21 and the rack sampler 22. The sample dispensing arm 25 is provided by a drive mechanism 4 so as to be able to move vertically up and down and rotate horizontally. The sample dispensing arm 25 holds a sample dispensing probe at one end.

[0036] The sample dispensing probe rotates along an arc-shaped rotational trajectory as the sample dispensing arm 25 rotates. The opening of the sample container held by the sample rack 221 on the rack sampler 22 is positioned along this rotational trajectory.

[0037] Furthermore, a sample discharge position is provided on the rotational trajectory of the sample dispensing probe for discharging the sample aspirated by the sample dispensing probe into the reaction tube 211. The sample discharge position corresponds to the intersection of the rotational trajectory of the sample dispensing probe and the movement trajectory of the reaction tube 211 held by the coagulation reaction unit 21.

[0038] Furthermore, the sample dispensing probe is driven by the drive mechanism 4 and moves vertically either directly above the opening of the sample container held by the sample rack 221 on the rack sampler 22, or at the sample dispensing position.

[0039] Furthermore, the sample dispensing probe, in accordance with the control circuit 9, aspirates a sample from the sample container located directly below it. The sample dispensing probe also, in accordance with the control circuit 9, discharges the aspirated sample into the reaction tube 211 located directly below the sample discharge position. The sample dispensing probe performs this series of aspiration and discharge operations once, for example, during one analysis cycle.

[0040] The first reagent dispensing arm 26 is provided, for example, between the coagulation reaction unit 21 and the reagent storage unit 23. The first reagent dispensing arm 26 is provided by a drive mechanism 4 so as to be able to move vertically up and down and rotate horizontally. The first reagent dispensing arm 26 holds the first reagent dispensing probe at one end.

[0041] The first reagent dispensing probe rotates along an arc-shaped rotational trajectory as the first reagent dispensing arm 26 rotates. A first reagent aspiration position for aspirating the first reagent is provided on this rotational trajectory. Furthermore, a first reagent discharge position for dispensing the reagent aspirated by the first reagent dispensing probe into the reaction tube 211 is set on the rotational trajectory of the first reagent dispensing probe. The first reagent discharge position corresponds to the intersection of the rotational trajectory of the first reagent dispensing probe and the movement trajectory of the reaction tube 211 held by the coagulation reaction unit 21.

[0042] The first reagent dispensing probe is driven by the drive mechanism 4 and moves vertically on its rotational trajectory at the first reagent aspiration position and the first reagent discharge position. The first reagent dispensing probe also aspirates the first reagent from the reagent container located directly below the first reagent aspiration position, according to the control circuit 9. The first reagent dispensing probe also discharges the aspirated first reagent into the reaction tube 211 located directly below the first reagent discharge position, according to the control circuit 9. The first reagent dispensing probe performs the series of aspiration and discharge operations for the first reagent once, for example, during one analysis cycle.

[0043] The second reagent dispensing arm 27 is provided, for example, between the coagulation reaction unit 21 and the reagent storage unit 23. The second reagent dispensing arm 27 is provided by a drive mechanism 4 so as to be able to move vertically up and down and rotate horizontally. The second reagent dispensing arm 27 holds a second reagent dispensing probe at one end.

[0044] The second reagent dispensing probe rotates along an arc-shaped rotational trajectory as the second reagent dispensing arm 27 rotates. A second reagent aspiration position for aspirating the second reagent is provided on this rotational trajectory. Furthermore, a second reagent discharge position for dispensing the reagent aspirated by the second reagent dispensing probe into the reaction tube 211 is set on the rotational trajectory of the second reagent dispensing probe. The second reagent discharge position corresponds to the intersection of the rotational trajectory of the second reagent dispensing probe and the movement trajectory of the reaction tube 211 held by the coagulation reaction unit 21.

[0045] The second reagent dispensing probe is driven by the drive mechanism 4 and moves vertically at the second reagent aspiration position and second reagent discharge position on its rotational trajectory. The second reagent dispensing probe also aspirates the second reagent from the reagent container located directly below the second reagent aspiration position, according to the control circuit 9. The second reagent dispensing probe also discharges the aspirated second reagent into the reaction tube 211 located directly below the second reagent discharge position, according to the control circuit 9. The second reagent dispensing probe performs the series of aspiration and discharge operations for the second reagent once, for example, during one analysis cycle.

[0046] The reaction tube arm 28 is provided between the solidification reaction unit 21 and the reaction tube storage section 24. The reaction tube arm 28 is provided by a drive mechanism 4 so as to be able to move vertically up and down and rotate horizontally. The reaction tube arm 28 holds a reaction tube holder at one end.

[0047] The reaction tube holder rotates along an arc-shaped rotational trajectory as the reaction tube arm 28 rotates. The reaction tube 211, held in the reaction tube storage unit 24, is positioned along this rotational trajectory. The reaction tube arm 28 holds the reaction tube 211 stored in the reaction tube storage unit 24 and places the held reaction tube 211 into the solidification reaction unit 21. The reaction tube arm 28 also removes the reaction tube 211 after measurement is complete from the solidification reaction unit 21 and transports it to the reaction tube disposal unit 241.

[0048] Furthermore, as shown in Figure 2, the analysis mechanism 2 further includes a biochemical reaction unit 29 that performs measurements related to biochemical tests on the sample. The biochemical reaction unit 29 is optional.

[0049] Next, we will explain in detail the configuration of the coagulation reaction unit 21. Figure 3 shows the internal structure of the solidification reaction unit 21. Figure 3 is a cross-sectional view of the solidification reaction unit 21, passing near the rotation axis of the solidification reaction unit 21 and showing the solidification reaction unit 21 in a cross-section parallel to the vertical direction. The solidification reaction unit 21 comprises a support 212 (see Figure 4), a reaction vessel 213, a cover 214, and a rotating connector 215.

[0050] The support 212 supports the entire coagulation reaction unit 21.

[0051] The reaction vessel 213 is mounted on the upper part of the support 212. The reaction vessel 213 is a rotary reaction vessel that rotates relative to the support 212 by a drive mechanism 4. The drive mechanism 4 that rotates the reaction vessel 213 is, for example, composed of a stepping motor. The drive mechanism 4 that rotates the reaction vessel 213 is an example of a drive unit. The reaction vessel 213 holds a plurality of reaction tubes 211 containing a mixture of sample and reagent, and transports the held reaction tubes 211 by repeatedly rotating and stopping.

[0052] The cover 214 is a cover provided on the top of the reaction vessel 213 to prevent external light from entering the reaction vessel 213. The cover 214 is detachably attached, for example, to the inner wall of the analysis mechanism 2 located near the solidification reaction unit 21. The cover 214 does not rotate together with the reaction vessel 213. The cover 214 may also be detachably attached to the support 212.

[0053] The rotary connector 215 is a connector that supplies power from outside the solidification reaction unit 21 to operate the various devices installed in the reaction vessel 213, and outputs signals and data generated by the various devices installed in the reaction vessel 213 to the outside of the solidification reaction unit 21. Examples of the various devices installed in the reaction vessel 213 include the photometric port 2131 and heater 2136, and temperature sensors, as described later. For example, the rotary connector 215 electrically connects the external units of the analysis mechanism 2, such as the units outside the reaction vessel, the analysis circuit 3, the control circuit 9, and the power supply, to the photometric port 2131, which is installed inside the solidification reaction unit 21, as described later. The rotary connector 215 is a connector that can electrically connect a rotating body to a fixed object. For example, a slip ring can be used as the rotary connector 215. However, other connectors that have a similar function to a slip ring (for example, connectors that make an electrical connection by contact via liquid metal) may also be used as the rotary connector 215. Note that the analysis mechanism 2, analysis circuit 3, control circuit 9, and power supply unit are all examples of the second unit.

[0054] Next, we will explain the configuration of the reaction vessel 213 in detail. Figure 4 is a perspective view showing the configuration of the reaction vessel 213. The reaction vessel 213 comprises an outer casing 2130 and a plurality of photometric ports 2131. Figure 5 is a perspective view showing the reaction vessel 213 with the outer casing 2130 removed from the reaction vessel 213 shown in Figure 4. The reaction vessel 213 also comprises a first substrate 2132, a second substrate 2133, and a plurality of third substrates 2135.

[0055] The reaction vessel 213 holds multiple photometric ports 2131 arranged in a ring. The photometric ports 2131 are located inside the reaction vessel 213. The photometric ports 2131 are fixed inside the reaction vessel 213 and rotate together with the reaction vessel 213. In addition, one photometric port 2131 is provided for each of the multiple reaction tubes 211 installed in the reaction vessel 213. When performing measurements, one reaction tube 211 is installed for each photometric port 2131. Each photometric port 2131 optically measures a predetermined component in the mixture of sample and reagent discharged into the reaction tube 211.

[0056] The configuration of the photometric ports 2131 is, for example, all the same. Figure 6 is a perspective view showing the configuration of the photometric port 2131. Figure 6 shows one photometric port 2131 removed from the reaction vessel 213. As shown in Figure 6, the photometric port 2131 has a reaction tube holder 21311, a light source 21312, and a light receiving unit 21313. Note that the configuration of the photometric ports 2131 does not have to be all the same. For example, multiple light sources 21312 may be provided in only some of the photometric ports.

[0057] The reaction tube 211 is installed in the reaction tube holder 21311. For example, the reaction tube holder 21311 has a hole into which the reaction tube 211 is inserted.

[0058] Each photometric port 2131 is provided with, for example, one reaction tube holder 21311, one light source 21312, and one light receiving unit 21313. In this case, one light source 21312 and one light receiving unit 21313 are provided for each reaction tube holder 21311. The light source 21312 and the light receiving unit 21313 are examples of photometric units that measure the mixed liquid contained in the reaction tube 211 installed in the reaction tube holder 21311. The light receiving unit 21313 is, for example, a photodetector including a photodiode. The photometric port 2131 irradiates light from the light source 21312 according to the control of the control circuit 9. The photometric port 2131 detects the scattered light generated when light is irradiated onto the reaction tube 211 inserted into the reaction tube holder 21311 using the light receiving unit 21313. Specifically, the light-receiving unit 21313 detects scattered light from light irradiated onto the mixed liquid in the reaction tube 211. The photometric port 2131 converts the light detected by the light-receiving unit 21313 into a weak electrical signal and outputs the converted electrical signal to the board unit 2134 via the third substrate 2135. The light source 21312 and the light-receiving unit 21313 are examples of photometric units.

[0059] Figure 7 is a magnified view of the vicinity of the photometric port 2131 in Figure 3. Figure 7 shows the reaction tube 211 installed in the photometric port 2131. As shown in Figure 7, the reaction vessel 213 is equipped with a heater 2136. Each photometric port 2131 is kept at a constant temperature by the heater 2136 installed inside the reaction vessel 213.

[0060] The heater 2136 is located below each photometric port 2131. The heater 2136 is, for example, a heating wire. The material of the heating wire is, for example, nichrome wire and iron-chromium wire. In the example shown in Figure 7, the heater 2136 consists of two heating wires arranged in a ring. The heater 2136 heats the photometric port 2131 under the control of the control circuit 9.

[0061] Furthermore, a temperature sensor may be provided near the photometric port 2131. Examples of temperature sensors include thermistors, resistance thermometers, thermocouples, and temperature sensor ICs. The temperature sensor measures the ambient temperature and outputs the measured temperature information to the control circuit 9. The temperature information is used in the control circuit 9 for temperature control to maintain a constant temperature for the mixed liquid contained in the reaction tube 211 installed at the photometric port 2131. For this reason, the heater 2136 may also be called a constant temperature unit.

[0062] The first substrate 2132 and the second substrate 2133 are, for example, rigid substrates. The first substrate 2132 and the second substrate 2133 are fixed inside the reaction vessel 213. Each of the first substrate 2132 and the second substrate 2133 is formed in a disc shape with an open central portion and is fixed near the center of the reaction vessel 213. The first substrate 2132 and the second substrate 2133 are electrically connected by cables (not shown) and function as a single substrate unit 2134.

[0063] Each of the third substrates 2135 extends from the inside to the outside in the reaction vessel 213. The third substrates 2135 are, for example, flexible printed circuits (FPCs). One end of each third substrate 2135 is connected to the substrate unit 2134, and the other end is connected to one of the multiple photometric ports 2131. The third substrates 2135 electrically connect the substrate unit 2134 to each photometric port 2131. The third substrates 2135 may also be connected to the second substrate 2133. Alternatively, cables may be used instead of the third substrates 2135.

[0064] The substrate unit 2134 is fixed inside the reaction vessel 213 and connected to each of the multiple photometric ports 2131. Specifically, the substrate unit 2134 is electrically connected to the rotary connector 215 via a cable (not shown). The cable connecting the rotary connector 215 and the substrate unit 2134 may be connected to the first substrate 2132 or to the second substrate 2133. Power supplied to the reaction vessel 213 from the outside via the rotary connector 215 is supplied to each photometric port 2131 via the substrate unit 2134 and the third substrate 2135, and measurements are taken at each photometric port 2131. The substrate unit 2134 is an example of the first unit.

[0065] The substrate unit 2134 has two functions: one that supplies power obtained from a power source located outside the reaction vessel 213 to each of the photometric ports 2131 (hereinafter referred to as the power supply function), and another that processes signals obtained from the photometric ports 2131, which have a photometric unit (hereinafter referred to as the signal processing function). The power supply function is an example of the first function, and the signal processing function is an example of the second function. The substrate unit 2134 uses the signal processing function to obtain analog signals from the photometric ports 2131 that indicate the photometric measurement results, amplifies the obtained analog signals, converts the amplified analog signals into digital signals, and outputs the converted digital signals to the outside of the solidification reaction unit 21. Specifically, an FPGA (Field-Programmable Gate Array) and circuits having amplifier and A / D converter functions are formed on the substrate of the substrate unit 2134. The board unit 2134 uses an FPGA to acquire analog signals from each photometric port 2131, amplifies the acquired analog signals using an amplifier function, converts the amplified analog signals into digital signals using an A / D converter function, and outputs the converted digital signals to the analysis circuit 3 via a rotary connector 215 using the FPGA. For example, the board unit 2134 acquires electrical signals from all photometric ports 2131 every 0.1 seconds. Circuits with other functions may be mounted on the board of the board unit 2134.

[0066] Since each photometric port 2131 is connected to an external unit via a circuit board unit 2134 connected to each photometric port 2131, the number of wires connecting the external unit to the circuit board unit 2134 is less than the number of wires connecting the circuit board unit 2134 to the photometric ports 2131. In other words, by using the circuit board unit 2134, the number of cables connecting the reaction vessel 213 to the external unit, as well as the number of wires and contacts in the rotary connector 215, can be reduced. Furthermore, digital data can be transmitted from the circuit board unit 2134 to the analysis circuit 3, for example, by serial communication. In this case, the number of cables connecting the reaction vessel 213 to the external unit can be further reduced.

[0067] Furthermore, the solidification reaction unit 21 is provided with a mechanism (hereinafter referred to as the heat suppression unit) that suppresses the transfer of heat generated in the substrate unit 2134 to the photometric port 2131. The heat suppression unit prevents the heat generated in the substrate unit 2134 from affecting the constant temperature function of the photometric port 2131.

[0068] In this embodiment, as shown in Figures 3 and 7, an insulating body 2137 is provided inside the reaction vessel 213 as a heat suppression section. The insulating body 2137 is a ring-shaped member that extends in an annular shape and is positioned between the photometric port 2131 and the substrate unit 2134, and is fixed to the upper and lower sides of the third substrate 2135, respectively. The insulating body 2137 is formed of a material with low thermal conductivity, for example. Examples of materials for forming the insulating body 2137 include foamed polyethylene, foamed urethane, foamed phenolic resin, foamed polyethylene, glass wool, cellulose fiber, wool breath, and carbonized cork.

[0069] The heat insulating body 2137 functions as a partition separating the area where the photometric port 2131 is located from the area where the substrate unit 2134 is located. The third substrate 2135 extends from the area where the photometric port 2131 is located to the area where the substrate unit 2134 is located, passing through the gap between the heat insulating bodies 2137. By providing the heat insulating body 2137, heat transfer between the area where the photometric port 2131 is located and the area where the substrate unit 2134 is located is suppressed. Therefore, the transfer of heat generated in the substrate unit 2134 to the photometric port 2131 is suppressed. The heat insulating body 2137 is an example of a suppression part. Alternatively, the heat insulating body 2137 may be constructed by stacking multiple heat insulating materials, with the third substrate 2135 passed between the stacked materials. Alternatively, the heat insulating body 2137 may be constructed from a single heat insulating material having an opening, with the third substrate 2135 passed through the opening.

[0070] Furthermore, the reaction vessel 213 is equipped with a fan 2138 and a vent 2139 as heat suppression parts to cool the substrate unit 2134. The fan 2138 and the vent 2139 are provided in the space where the substrate unit 2134 is placed.

[0071] The fan 2138 is attached to the outer casing 2130 in the portion that forms the upper surface of the reaction vessel 213. The fan 2138 is positioned above the substrate unit 2134, for example, in the central part of the reaction vessel 213.

[0072] Fan 2138 connects the inside and outside of the reaction vessel 213. Fan 2138 comprises a propeller and a motor that rotates the propeller. The motor of fan 2138 is electrically connected to a rotary connector 215 via a cable (not shown). Power is supplied from the outside via the rotary connector 215, which drives the motor and rotates the propeller. As a result, fan 2138 expels air from inside the reaction vessel 213 to the outside of the reaction vessel 213. Fan 2138 is an example of a first fan. Fan 2138 generates an airflow that cools the substrate unit 2134.

[0073] The vent 2139 is provided, for example, at the bottom of the reaction vessel 213. The vent 2139 is a hole that connects the outside and inside of the reaction vessel 213. There may be one vent 2139 or there may be multiple vents.

[0074] Figure 8 is a diagram illustrating the airflow inside the reaction vessel 213 shown in Figure 3. In the area where the substrate unit 2134 is placed, when the air inside the reaction vessel 213 is discharged to the outside of the reaction vessel 213 via the fan 2138, air from the lower side of the reaction vessel 213 flows into the reaction vessel 213 through the vent 2139. The substrate unit 2134 is then cooled by the continuous influx of air from outside the reaction vessel 213 into the reaction vessel 213.

[0075] The control circuit 9 controls, via the system control function 91, the setting and updating of execution information based on analysis request information, the movement of the sample rack 221, the rotation and dispensing of the sample dispensing arm 25, the rotation of the reagent rack, the rotation and dispensing of the first reagent dispensing arm 26, the rotation and dispensing of the second reagent dispensing arm 27, and the rotation and transport of the reaction tube arm 28. In addition, the control circuit 9 controls, via the system control function 91, the rotation of the reaction vessel 213, the measurement operation by the photometric port 2131, the heating state of the heater 2136, and the operating state of the fan 2138.

[0076] The effects of the automated analyzer 1 according to this embodiment will be described below.

[0077] The automated analyzer 1 according to this embodiment comprises a reaction vessel 213, a plurality of photometric ports 2131 fixed to the reaction vessel 213, and a drive mechanism 4. Each photometric port 2131 includes a reaction tube holder 21311 that contains a mixture of a sample and a reagent, and a photometric unit comprising a light source 21312 and a light receiving unit 21313 for measuring the mixture contained in the reaction tube 211. The light source 21312 and light receiving unit 21313 are provided for each reaction tube holder 21311. The reaction vessel 213, equipped with a plurality of photometric ports 2131, transports the reaction tube 211 held by the reaction tube holder 21311 by repeatedly rotating and stopping. The drive mechanism 4 rotates the reaction vessel 213.

[0078] With the above configuration, in the automated analyzer 1 according to this embodiment, the reaction vessel 213 for measuring blood coagulation is formed in a circular shape, and the reaction vessel 213 is rotated by the drive mechanism 4. Multiple photometric units called photometric ports 2131 are fixed inside the reaction vessel 213, and measurements are performed by placing disposable reaction tubes 211 in each photometric port 2131. By performing measurements using multiple photometric ports 2131, the throughput of the test can be improved compared to when there is only one photometric unit. Furthermore, by using a rotating reaction vessel 213, the reaction tubes 211 placed in the photometric ports 2131 can be transported, so that samples and reagents can be dispensed into each reaction tube 211, and each reaction tube 211 can be installed and removed at a specific location. For this reason, the structure and operation of the mechanism for dispensing samples and reagents into the reaction tubes 211, and the mechanism for installing and removing the reaction tubes 211 can be simplified and miniaturized. In other words, the operation of the mechanism for accessing the reaction vessel 213 that performs blood coagulation can be simplified, and the number of units provided in the automated analyzer 1 and the overall size of the automated analyzer 1 can be optimized while improving the throughput of the test.

[0079] Furthermore, the automated analyzer 1 according to this embodiment further comprises a substrate unit 2134. The substrate unit 2134 is installed inside the reaction vessel 213 and is connected to each of the multiple photometric ports 2131. The substrate unit 2134 has a power supply function that supplies power obtained from a power source installed outside the reaction vessel 213 to each photometric port 2131, and a signal processing function that processes the signals obtained from the photometric ports 2131.

[0080] The signal processing function includes, for example, a function to acquire analog signals indicating the photometric results from each photometric port 2131, a function to amplify the acquired analog signals, a function to convert the amplified analog signals into digital signals, and a function to output the converted digital signals to the outside of the reaction vessel 213.

[0081] Since each photometric port 2131 is connected to an external unit using a circuit board unit 2134 connected to each photometric port 2131, the number of wires connecting the external unit to the circuit board unit 2134 is less than the number of wires connecting the circuit board unit 2134 to the photometric port 2131. Therefore, the number of cables connecting each photometric port 2131 to the external unit, as well as the number of wires and contacts in the rotary connector 215, can be reduced.

[0082] Furthermore, the automatic analyzer 1 according to this embodiment further includes a rotary connector 215 that electrically connects the external unit of the reaction vessel 213 and the photometric port 2131. For example, a slip ring can be used as the rotary connector 215. By using the rotary connector 215, it becomes possible to transmit power to operate the photometric port 2131 and electrical signals indicating the measurement results at the photometric port 2131 between the photometric port 2131, which rotates together with the reaction vessel 213, and the external unit.

[0083] Furthermore, the reaction vessel 213 according to this embodiment is further equipped with a heat suppression unit that suppresses the transfer of heat generated in the substrate unit 2134 to the photometric port 2131. This configuration suppresses the effect of heat generated in the substrate unit 2134 on the constant temperature function of the photometric port 2131.

[0084] The reaction vessel 213 according to this embodiment is equipped with an insulating body 2137 as a heat suppression section. The insulating body 2137 is made of a material with low thermal conductivity and functions as a partition provided inside the reaction vessel 213 between each photometric port 2131 and the substrate unit 2134. By providing the insulating body 2137, the space in which the photometric port 2131 is located and the space in which the substrate unit 2134 is located are separated, and the transfer of heat generated in the substrate unit 2134 to the photometric port 2131 is suppressed.

[0085] The reaction vessel 213 according to this embodiment includes a fan 2138 that discharges air from inside the reaction vessel 213 to the outside, and a vent 2139 that allows air from outside the reaction vessel 213 to flow into the inside of the reaction vessel 213, as a heat suppression unit. The presence of the fan 2138 and the vent 2139 generates airflow inside the reaction vessel 213, and the generated airflow cools the substrate unit 2134. As a result of the cooling of the substrate unit 2134, the transfer of heat generated in the substrate unit 2134 to the photometric port 2131 is suppressed.

[0086] (First variation) A first modification of the embodiment will now be described. This modification is a modification of the embodiment's configuration as follows. In this modification, in addition to the fan 2138 provided inside the reaction vessel 213 as a mechanism for cooling the substrate unit 2134, a second fan is provided to cool the air outside the reaction vessel 213. The same configuration, operation, and effects as in the embodiment will not be described.

[0087] Figure 9 shows the internal configuration of the solidification reaction unit 21 according to this modified example. Figure 9 is a cross-sectional view showing the solidification reaction unit 21 in a cross-section parallel to the vertical direction, passing near the rotation axis of the solidification reaction unit 21. As shown in Figure 9, the solidification reaction unit 21 further includes a fan 216 and a temperature sensor 217 as a heat suppression unit.

[0088] The fan 216 is located outside the reaction vessel 213 and circulates the air near the vent 2139. For example, the fan 216 is positioned below the reaction vessel 213. The fan 216 is attached, for example, to the inner wall of the analysis mechanism 2 located near the solidification reaction unit 21. The fan 216 may be fixed to the support 212. The fan 216 cools the reaction vessel 213 by circulating the air present in the space below it, according to the control of the control circuit 9. For example, the fan 216 circulates the air present in the space below the reaction vessel 213 by sending it outwards. As the air present in the space below the reaction vessel 213 is cooled, the cooled air flows into the inside of the reaction vessel 213 through the vent 2139. The fan 216 is an example of a second fan.

[0089] The temperature sensor 217 is a sensor that detects the temperature of the surrounding air. For example, the fan 216 is fixed to a support 212, for example, on the underside of the reaction vessel 213. The temperature sensor 217 detects the temperature of the air cooled by the fan 216. Examples of temperature sensors 217 include thermistors, resistance thermometers, thermocouples, and temperature sensor ICs. The temperature sensor 217 outputs the detected temperature information to the control circuit 9.

[0090] The control circuit 9 controls the operating state of the fan 216 according to the detection result of the temperature sensor 217. For example, if the temperature detected by the temperature sensor 217 is below a set value, the control circuit 9 determines that the temperature of the air used to cool the circuit board unit 2134 is sufficiently low and stops the fan 216. On the other hand, if the temperature detected by the temperature sensor 217 exceeds the set value, the control circuit 9 determines that the air used to cool the circuit board unit 2134 is warm and activates the fan 216 to cool the air used to cool the circuit board unit 2134. The control circuit 9 is an example of a control unit.

[0091] The effects of the automated analyzer 1 according to this modified example will be explained below.

[0092] In this modified version, the automatic analyzer 1 uses a vent 2139 to draw in air from the bottom of the reaction vessel 213 and uses the drawn-in air to cool the substrate unit 2134. Therefore, if heat accumulates inside the automatic analyzer 1 and the air used for cooling itself becomes warm, the cooling effect on the substrate unit 2134 will be weakened.

[0093] The modified automatic analyzer 1 further includes a fan 216 located outside the reaction vessel 213, which circulates the air near the vent 2139. The addition of the fan 216 circulates the air used to cool the substrate unit 2134, preventing heat from accumulating inside the automatic analyzer 1. This makes it less likely for the temperature of the air used to cool the substrate unit 2134 to rise, thereby improving the cooling performance of the substrate unit 2134.

[0094] Furthermore, the automated analyzer 1 according to this modified example includes a temperature sensor 217 that detects the temperature of the air near the vent 2139, and a control circuit 9 that controls the operating state of the fan 216 according to the temperature detected by the temperature sensor 217. For example, by monitoring the temperature of the air used to cool the substrate unit 2134 with the temperature sensor 217 and operating the fan 216 only when the air temperature exceeds a set value, the cooling performance of the substrate unit 2134 can be improved in a power-saving and effective manner.

[0095] Alternatively, the fan 216 may be operated continuously while measurements are being taken in the coagulation reaction unit 21, without using the temperature sensor 217 for control. In this case, the temperature sensor 217 may not be provided.

[0096] Alternatively, the temperature sensor 217 may be placed inside the reaction vessel 213. In this case, the temperature sensor 217 detects the temperature of the air flowing into the reaction vessel 213 through the vent 2139 and outputs the detection result to the control circuit 9 via the rotary connector 215. The control circuit 9 controls the operating state of the fan 216 according to the temperature of the air flowing into the reaction vessel 213, thereby preventing the temperature of the air used to cool the substrate unit 2134 from becoming too high.

[0097] (Second variation) A second modification of the embodiment will now be described. This modification is a modification of the configuration of the embodiment as follows. In this modification, in addition to the fan 2138 provided inside the reaction vessel 213 as a mechanism for cooling the substrate unit 2134, an enclosure for storing air in the space below the reaction vessel is installed. The same configuration, operation, and effects as in the embodiment will not be described.

[0098] Figure 10 shows the internal configuration of the solidification reaction unit 21 according to this modified example. Figure 10 is a cross-sectional view showing the solidification reaction unit 21 in a cross-section parallel to the vertical direction, passing near the rotation axis of the solidification reaction unit 21. As shown in Figure 10, the solidification reaction unit 21 includes a storage unit 218, a fan 219, and a temperature sensor 2110 as a heat suppression unit.

[0099] The storage section 218 is located outside the reaction vessel 213. For example, the storage section 218 is fixed to a support 212 (not shown) below the reaction vessel 213. The storage section 218 stores air that flows into the inside of the reaction vessel 213 through the vent 2139. The storage section 218 is formed by an enclosure that surrounds the air flowing into the inside of the reaction vessel 213 through the vent 2139. The enclosure forming the storage section 218 is formed, for example, from a metal plate.

[0100] Fan 219 is attached to the storage section 218. Fan 219 reduces heat buildup inside the storage section 218 by drawing outside air into the storage section 218, thus preventing the temperature of the air used to cool the substrate unit 2134 from becoming too high. The air that flows into the storage section 218 passes through the vent 2139 and flows into the reaction vessel 213, where it is used to cool the substrate unit 2134. Fan 219 is an example of a third type of fan.

[0101] The temperature sensor 2110 is installed inside the storage section 218 and detects the temperature of the air inside the storage section 218. Examples of temperature sensors 2110 include thermistors, resistance thermometers, thermocouples, and temperature sensor ICs. The temperature sensor 2110 outputs the detected temperature information to the control circuit 9.

[0102] The control circuit 9 controls the operating state of the fan 219 according to the detection result of the temperature sensor 2110. For example, if the temperature detected by the temperature sensor 2110 is below a set value, the control circuit 9 determines that the temperature of the air inside the storage unit 218 is sufficiently low and stops the fan 216. On the other hand, if the temperature detected by the temperature sensor 2110 exceeds the set value, the control circuit 9 determines that the air inside the storage unit 218 is warm and activates the fan 219. The control circuit 9 is an example of a control unit.

[0103] The effects of the automated analyzer 1 according to this modified example will be explained below.

[0104] The automated analyzer 1 according to this modified example further includes a storage unit 218 located outside the reaction vessel 213 that stores air flowing into the reaction vessel 213 through a vent 2139, and a fan 219 provided in the storage unit 218 that brings air from outside the storage unit 218 into the storage unit 218. By providing the fan 219 in the storage unit 218 where air used for cooling the substrate unit 2134 is stored, the air used for cooling the substrate unit 2134 can be efficiently replaced, improving the cooling performance of the substrate unit 2134.

[0105] Furthermore, the automated analyzer 1 according to this modified example includes a temperature sensor 2110 for detecting the temperature of the air inside the storage section 218, and a control circuit 9 for controlling the operating state of the fan 219 according to the temperature detected by the temperature sensor 2110. For example, by monitoring the temperature of the air inside the storage section 218 with the temperature sensor 2110 and operating the fan 219 only when the air temperature exceeds a set value, the cooling performance of the substrate unit 2134 can be improved in a power-saving and effective manner.

[0106] Alternatively, the fan 219 may be operated continuously while measurements are being taken in the coagulation reaction unit 21, without using the temperature sensor 2110 for control. In this case, the temperature sensor 2110 may not be required.

[0107] Alternatively, the temperature sensor 2110 may be placed inside the reaction vessel 213. In this case, the temperature sensor 2110 detects the temperature of the air introduced into the storage section 218 by the fan 219 and flowing into the reaction vessel 213 through the vent 2139, and outputs the detection result to the control circuit 9 via the rotary connector 215. The control circuit 9 controls the operating state of the fan 219 according to the temperature of the air flowing into the reaction vessel 213, thereby preventing the temperature of the air used to cool the substrate unit 2134 from becoming too high.

[0108] (Third variation) A third modification of the embodiment will now be described. This modification is a modification of the embodiment's configuration as follows. In this modification, a region is provided on the substrate where heat-generating elements are concentrated, and a mechanism for cooling the substrate unit 2134 is placed near this region. The same configuration, operation, and effects as in the embodiment will not be described.

[0109] Figure 11 shows the internal configuration of the solidification reaction unit 21 according to this modified example. Figure 11 is a cross-sectional view showing the solidification reaction unit 21 in a cross-section parallel to the vertical direction, passing near the rotation axis of the solidification reaction unit 21.

[0110] As shown in Figure 11, the second substrate 2133 constituting the substrate unit 2134 is provided with a heat-generating concentration area 21331. Elements to be placed on the second substrate 2133 are concentrated in the heat-generating concentration area 21331. Therefore, while measurements are being taken in the solidification reaction unit 21, the amount of heat generated in the heat-generating concentration area 21331 is greater than in other areas on the second substrate 2133.

[0111] The fan 2138 is located near the heat-generating area 21331 and cools the heat-generating area 21331 according to the control of the control circuit 9. The fan 2138 is positioned to concentrate the cooling of the heat-generating area 21331 by blowing air toward it. For example, as shown in Figure 11, the fan 2138 is positioned on the bottom surface of the reaction vessel 213, directly below the heat-generating area 21331. The fan 2138 only needs to be positioned to concentrate the cooling of the heat-generating area 21331, and may be positioned above or to the side of the substrate unit 2134. The fan 2138 also circulates the air inside the reaction vessel 213 by drawing outside air into the reaction vessel 213.

[0112] The effects of the automated analyzer 1 according to this modified example will be explained below.

[0113] In the modified automated analyzer 1, the second substrate 2133 of the substrate unit 2134 is provided with a heat-generating area 21331 where heat-generating elements are concentrated. The fan 2138 is also provided near the heat-generating area 21331. This configuration allows the heat-generating area 21331, where heat-generating elements are concentrated, to be concentratedly cooled by the fan 2138, thereby improving the cooling performance of the substrate unit 2134.

[0114] (Fourth variation) A fourth modification of the embodiment will now be described. This modification is a modification of the configuration of the embodiment as follows. The same configuration, operation, and effects as in the embodiment will not be described. In this modification, one of the power supply function and signal processing function that the board unit 2134 has in the above-described embodiment is provided to the board unit 2134, and the other is provided to an external unit. For example, the power supply function to each photometric port 2131 may be provided to the power supply device instead of the board unit 2134. Alternatively, for example, the signal processing function related to each photometric port 2131 may be provided to the analysis circuit 3 instead of the board unit 2134.

[0115] (Fifth variation) A fourth modification of the embodiment will now be described. This modification is a modification of the configuration of the embodiment as follows. In this modification, instead of the substrate unit 2134 fixed inside the reaction vessel 213, the same configuration, operation, and effects as in the embodiment will not be described. Both the power supply function and the signal processing function that the substrate unit 2134 has in the above embodiment are provided to an external unit. For example, the power supply function to each photometric port 2131 may be provided to the power supply device instead of the substrate unit 2134, and the signal processing function related to each photometric port 2131 may be provided to the analysis circuit 3 instead of the substrate unit 2134. Furthermore, the substrate unit 2134 may not be provided at all. (Sixth variation) A sixth modification of the embodiment will now be described. The same configuration, operation, and effects as in the embodiment will not be described. This modification is a modification of the configuration of the embodiment as follows. In this modification, the fan 2138 rotates in the opposite direction to that of the embodiment, drawing air from outside the reaction vessel 213 into the reaction vessel 213. The air then flows in the opposite direction to the airflow shown in Figure 8. The air inside the reaction vessel 213 is discharged to the outside of the reaction vessel 213 through the vent 2139.

[0116] In this modified version as well, the substrate unit 2134 is cooled by the continuous flow of air from outside the reaction vessel 213 into the vicinity of the substrate unit.

[0117] According to at least one embodiment described above, the throughput of testing by an automated analyzer can be improved.

[0118] While several embodiments have been described, these embodiments are presented as examples only and are not intended to limit the scope of the invention. These embodiments can be implemented in a variety of other forms, and various omissions, substitutions, modifications, and combinations of embodiments are possible without departing from the spirit of the invention. These embodiments and their variations are included in the scope and spirit of the invention, as well as in the claims and their equivalents. With respect to the above embodiments, the following additional notes are disclosed as aspects of the invention and selective features. (Note 1) Multiple reaction tube holders for holding reaction tubes containing a mixture of sample and reagent, A plurality of photometric units are provided for each of the plurality of reaction tube holding units, which measure the mixed liquid contained in the reaction tube, A reaction tank comprising the plurality of reaction tube holding units and the plurality of photometric units, which transports the reaction tubes held by each of the plurality of reaction tube holding units by repeatedly rotating and stopping, A drive unit for rotating the reaction vessel, An automated analyzer equipped with the following features. (Note 2) The reactor further comprises a first unit fixed inside the reactor and connected to each of the plurality of photometric units, The first unit may include at least one of the following functions: a first function that supplies power obtained from a power source to each of the plurality of photometric units, and a second function that processes signals obtained from each of the plurality of photometric units. (Note 3) The reactor may further include a rotary connector that electrically connects the second unit, which is located outside the reactor, to the first unit.

[0119] A rotary connector is a connector that can electrically connect a rotating body to a stationary object. (Note 4) The number of wires connecting the second unit, which is provided outside the reaction vessel, to the first unit may be less than the number of wires connecting the first unit to the photometric unit. (Note 5) The second function may include a function to acquire an analog signal indicating the photometric result from the photometric unit, a function to amplify the acquired analog signal, a function to convert the amplified analog signal into a digital signal, and a function to output the converted digital signal to the second unit. (Note 6) The system may further include a heat suppression unit that prevents heat generated in the first unit from being transferred to the photometric unit. (Note 7) The heat suppression section may be made of a material with low thermal conductivity and may include a partition provided between the photometric section and the first unit inside the reaction vessel. (Note 8) The heat suppression unit may include a first fan that generates an airflow to cool the first unit. (Note 9) The heat suppression unit may be equipped with a vent that allows air from outside the reaction vessel to flow into the reaction vessel, and the first fan may discharge air from inside the reaction vessel to the outside. (Note 10) The heat suppression unit is provided with a vent for discharging air from inside the reaction vessel to the outside of the reaction vessel, and the first fan may bring air from outside the reaction vessel into the inside of the reaction vessel. (Note 11) The reaction vessel may further be provided with a second fan located outside the reaction vessel to circulate the air near the vent. (Note 12) A sensor for detecting the temperature of the air near the vent, A control unit that controls the operating state of the second fan according to the detection result of the sensor, It may also be provided. (Note 13) A storage section provided outside the reaction vessel for storing air that flows into the inside of the reaction vessel through the vent, A third fan is provided in the storage section and causes air from outside the storage section to flow into the storage section. It may also be provided. (Note 14) A sensor for detecting the temperature of the air inside the storage section, A control unit that controls the operating state of the third fan according to the detection result of the sensor, It may also be provided. (Note 15) The first unit includes a heat-generating area where heat-generating elements are concentrated, The fan may be provided near the heat-generating area. (Note 16) The first unit comprises one of the first function and the second function, The second unit may have functions that are different from the functions provided in the first unit, among the first and second functions. (Note 17) The rotary connector may electrically connect the first unit and the second unit through solid-to-solid contact. (Note 18) The rotary connector may electrically connect the first unit and the second unit by contact via liquid metal. (Note 19) The rotary connector may include slip rings that make electrical connections through contact between solids while sliding against each other. (Note 20) The rotary connector may electrically connect the second unit and the first fan. (Note 21) Multiple reaction tube holders for holding reaction tubes containing a mixture of sample and reagent, A plurality of photometric units are provided for each of the reaction tube holding sections, which measure the mixed liquid contained in the reaction tube, A reaction tank comprising the reaction tube holding section and the photometric section, which transports the reaction tube held by the reaction tube holding section by repeatedly rotating and stopping, A drive unit for rotating the reaction vessel, A processing unit is provided outside the reaction tank 213, A rotary connector connecting the photometer and the processing unit, An automated analyzer equipped with the following features. [Explanation of symbols]

[0120] 1…Automatic analyzer 2…Analysis mechanism 3…Analysis circuit 4…Drive mechanism 5…Input Interface 6…Output Interface 7…Communication Interface 8…Memory circuit 9...Control circuit 91... System control function 21... Coagulation reaction unit 22... Rack Sampler 221… Sample rack 23… Reagent storage 24…Reaction tube storage section 25… Sample dispensing arm 26…Reagent dispensing arm 27… Reagent dispensing arm 28…Reaction tube arm 29…Biochemical Reaction Unit 211…Reaction tube 212...Support 213…Reaction vessel 214...cover 215... Rotating connector 2130... Exterior 2131... Photometric port 2132, 2133, 2135… circuit boards 21331... Heat concentration area 2134... Circuit board unit 2136... Heater 2137... Insulator 2138...fan 2139...Ventilation opening 21311... Reaction tube holder 21312…Light source 21313...Light receiving section 216, 219...fan 217, 2110… Temperature sensors 218... Storage section

Claims

1. Multiple reaction tube holders for holding reaction tubes containing a mixture of sample and reagent, A plurality of photometric units are provided for each of the plurality of reaction tube holding units, which measure the mixed liquid contained in the reaction tube, A reaction tank comprising the plurality of reaction tube holding units and the plurality of photometric units, which transports the reaction tubes held by each of the plurality of reaction tube holding units by repeatedly rotating and stopping, A drive unit for rotating the reaction vessel, A first unit fixed inside the reaction vessel and connected to each of the multiple photometric units, A rotary connector electrically connects the second unit and the first unit, which are located outside the reaction vessel. A first fan generates an airflow to cool the first unit, A second fan is provided outside the reaction vessel, Equipped with, The first unit includes at least one of the following functions: a first function that supplies power obtained from a power source to each of the plurality of photometric units, and a second function that processes signals obtained from each of the plurality of photometric units. The reaction vessel is equipped with a vent that allows outside air to flow into the inside of the reaction vessel. The first fan discharges the air inside the reaction vessel to the outside of the reaction vessel. The second fan circulates the air near the vent. Automatic analyzer.

2. A sensor for detecting the temperature of the air near the vent, A control unit that controls the operating state of the second fan according to the detection result of the sensor, The automatic analyzer according to claim 1, further comprising:

3. The vent is provided at the bottom of the reaction vessel, The first fan is installed at the top of the reaction vessel and generates an airflow to draw in air from outside the reaction vessel through the vent into the reaction vessel, and to discharge air from inside the reaction vessel to the outside of the reaction vessel from the top of the reaction vessel. The automated analyzer according to claim 1.

4. The number of wires connecting the second unit, which is located outside the reaction vessel, to the first unit is less than the number of wires connecting the first unit to each of the multiple photometric units. The automated analyzer according to claim 1.

5. The second function includes a function to acquire an analog signal indicating the photometric result from the photometric unit, a function to amplify the acquired analog signal, a function to convert the amplified analog signal into a digital signal, and a function to output the converted digital signal to the second unit. The automated analyzer according to claim 4.

6. The device further includes a heat suppression unit that prevents heat generated in the first unit from being transferred to the photometric unit. The automated analyzer according to claim 4 or 5.

7. The heat suppression section is formed of a material with low thermal conductivity and includes a partition provided between the photometric section and the first unit inside the reaction vessel. The automated analyzer according to claim 6.

8. A plurality of reaction tube holders for holding reaction tubes containing a mixture of a sample and a reagent, A plurality of photometric units are provided for each of the plurality of reaction tube holding units, which measure the mixed liquid contained in the reaction tube, A reaction tank comprising the plurality of reaction tube holding units and the plurality of photometric units, which transports the reaction tubes held by each of the plurality of reaction tube holding units by repeatedly rotating and stopping, A drive unit for rotating the reaction vessel, A first unit fixed inside the reaction vessel and connected to each of the multiple photometric units, A rotary connector electrically connects the second unit and the first unit, which are located outside the reaction vessel. A first fan generates an airflow to cool the first unit, A storage section provided outside the reaction vessel, A third fan is provided in the storage section, Equipped with, The first unit includes at least one of the following functions: a first function that supplies power obtained from a power source to each of the plurality of photometric units, and a second function that processes signals obtained from each of the plurality of photometric units. The reaction vessel is equipped with a vent that allows outside air to flow into the inside of the reaction vessel. The first fan discharges the air inside the reaction vessel to the outside of the reaction vessel. The storage section stores the air that flows into the inside of the reaction vessel through the vent, The third fan brings air from outside the storage section into the storage section. Automatic analyzer.

9. A sensor for detecting the temperature of the air inside the storage section, A control unit that controls the operating state of the third fan according to the detection result of the sensor, The automatic analyzer according to claim 8, further comprising:

10. The first unit includes a heat-generating area where heat-generating elements are concentrated, The first fan is provided near the heat-generating area. An automated analyzer according to any one of claims 1 to 9.

11. The first unit is equipped with one of the first function and the second function, The second unit includes the first function and a function of the second function that is different from the function provided in the first unit. The automated analyzer according to claim 1.

12. The automatic analyzer according to claim 1 or 11, wherein the rotating connector electrically connects the first unit and the second unit by solid-to-solid contact.

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