Carriers for elements of tumor treatment electric field provisioning systems, and systems and methods using these carriers.

Abstract

A system for applying a tumor-treating electric field to a portion of a subject's body is disclosed. The system includes a carrier having a carrier body defining a receiving space and a coupling device configured to fixedly couple the carrier body to a first location on the subject's body. An electric signal generator is at least partially received within the receiving space of the carrier body. At least one transducer array is in electrical communication with the electric signal generator. Each transducer array of the at least one transducer array is configured to be securely positioned at a respective second location on the subject's body, each second location being different from the first location.

Description

Technical Field

[0001] Cross - reference to Related Applications This application claims the benefit and priority of the filing date of U.S. Provisional Patent Application No. 63 / 168,416, filed Mar. 31, 2021, which is hereby incorporated by reference in its entirety.

[0002] The present disclosure relates to systems and methods for providing tumor treatment fields, and more particularly, to systems and methods for improving the mobility of a subject receiving a tumor treatment field.

Background Art

[0003] Tumor treatment fields (TTF) can be used to treat various types of cancer. For example, TTF can be applied to a portion of a subject's body via one or more transducer arrays. Generally, the transducer array is coupled to a signal generator that generates the TTF via the transducer array. The signal generator is typically carried in a handbag - like travel bag, and one or more cables extend between the transducer array and the signal generator.

[0004] Thus, the subject is tethered to the signal generator by the cable. If the subject accidentally moves too far away from the signal generator, the signal generator may be disconnected from the transducer array, thereby activating an alarm and drawing unnecessary attention to the subject, or the transducer array may be pulled from the desired location on the subject's body. Further, movement between the subject, the signal generator, and the cable can cause strain on the cable (e.g., at cable joints or attachment locations), which can cause the cable to wear out or break entirely. Thus, a system that allows the subject to move freely (e.g., stand, sit, walk, and exercise) without causing significant wear or strain on the cable and without the subject having to lift and carry the signal generator is desirable.

[0005] Furthermore, handbags resembling suitcases are meant to attract attention and draw the eye, minimizing the chance of other passersby tripping over them or accidentally knocking them over. Therefore, handbags can attract unwanted attention and may not look aesthetically pleasing. A more discrete system would be preferable. [Prior art documents] [Patent Documents]

[0006] [Patent Document 1] U.S. Patent No. 7,565,205 [Overview of the project] [Means for solving the problem]

[0007] This specification describes systems for applying a tumor-treating electric field to a portion of a target body in various embodiments. The system may comprise a carrier having a carrier body defining an acceptance space and a coupling device configured to fixate the carrier body to a first position on the target body. An electrical signal generator can be at least partially accepted within the acceptance space of the carrier body. At least one transducer array can be electrically communicated with the electrical signal generator. Each transducer array of the at least one transducer array may be configured to be reliably positioned at a second location on the target body, the second location being different from the first location.

[0008] Additional advantages of the present invention are partially described in the following description, partially evident from the description, or can be learned by practicing the invention. The advantages of the present invention are realized and achieved particularly by the elements and combinations indicated in the appended claims. It should be understood that both the above general description and the following detailed description are illustrative and descriptive only and do not limit the claimed invention.

[0009] These and other features of preferred embodiments of the present invention will become more apparent in a detailed description with reference to the accompanying drawings below. [Brief explanation of the drawing]

[0010] [Figure 1] This is a schematic diagram of an object equipped with the system disclosed herein. [Figure 2] This is a front view of an object in an upright position wearing the system disclosed herein. [Figure 3] This is a partial top view of a subject in a seated position, wearing a system similar to that shown in Figure 2. [Figure 4] This is a front view of an exemplary carrier of the system disclosed herein. [Figure 5A] This is a perspective view of an exemplary electrical junction box. [Figure 5B] This is a schematic side view of another exemplary electrical junction box. [Figure 6] This is a schematic diagram of an object fitted with various carriers at various positions as disclosed herein. [Figure 7] This is a block diagram of an operating environment comprising the computing system disclosed herein. [Figure 8A] This shows a rear view of an object fitted with a carrier according to an embodiment disclosed herein. [Figure 8B] A side view of the subject and carrier, similar to that shown in Figure 8A, is presented. [Figure 9A] This document shows a front view of an object fitted with a carrier according to an embodiment disclosed herein. [Figure 9B] A side view of the subject and carrier, similar to that shown in Figure 9A, is presented. [Figure 10A] This specification shows a front view of the lower body of an object fitted with a carrier according to an embodiment disclosed herein. [Figure 10B] Figure 10A shows a side view of the lower body of the subject and carrier, similar to Figure 10A.

Best Mode for Carrying Out the Invention

[0011] Next, the present invention will be described more fully below, with reference to the accompanying drawings. The drawings do not necessarily show all embodiments of the present invention. In fact, the present invention may be embodied in many different forms and should not be construed as limited to the embodiments described herein. Rather, these embodiments are provided so that this disclosure will satisfy applicable legal requirements. The same numbers refer to the same elements throughout the specification. It is to be understood that the present invention is not limited to the particular methods and protocols described, and thus may be modified. It is also to be understood that the terms used herein are for the purpose of describing particular embodiments only and are not intended to limit the scope of the present invention.

[0012] Those skilled in the art to which the present invention pertains and who have the benefit of the teachings presented in the above description and the related drawings will envision many modifications and other embodiments of the present invention described herein. Accordingly, it is to be understood that the present invention is not limited to the particular embodiments disclosed, and that modifications and other embodiments are intended to be included within the scope of the appended claims. Although specific terms are employed herein, they are used in a generic and descriptive sense only and not for purposes of limitation.

[0013] As used herein, the singular forms "a", "an", and "the" also include plural referents unless the context clearly dictates otherwise. For example, the use of the terms "transducer array" or "strap" can refer to one or more such transducer arrays or straps.

[0014] All technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs, unless specifically defined otherwise.

[0015] A range can be expressed in this specification as from "about" one particular value and / or to "about" another particular value. When such a range is expressed, another aspect includes from one particular value and / or to another particular value. Similarly, when a value is expressed as an approximation, it will be understood that the use of the antecedent "about" forms another aspect of the particular value. It will be further understood that each endpoint of a range is significant both in relation to the other endpoint and independently of the other endpoint. In some cases, in some aspects, when a value is approximated by use of the antecedent "about", it is contemplated that values (greater or lesser) up to 15%, up to 10%, up to 5%, or up to 1% of the particular stated value can be included within the scope of those aspects. Similarly, in some optional aspects, when a value is approximated by use of the terms "substantially" or "generally", it is contemplated that values (greater or lesser) up to 15%, up to 10%, up to 5%, or up to 1% of the particular value can be included within the scope of those aspects. "Substantially" or "generally" can refer to a degree of deviation that is sufficiently small so as not to appreciably worsen the identified characteristic or situation when used in relation to the identified characteristic or situation, and the exact degree of deviation tolerated may in some cases depend on the particular context.

[0016] As used herein, the terms "any" or "in some cases" mean that the event or situation described can or cannot occur substantially, and the description means that the examples where the above event or situation occurs and the examples where it does not occur are included.

[0017] As used herein, the term "at least one of" is intended to be synonymous with "one or more of". For example, "at least one of A, B, and C" explicitly includes only A, only B, only C, and each combination.

[0018] As used herein, the word "or" means any single element in a given list, and also includes any combination of elements in that list.

[0019] Unless otherwise specified, it should be understood that no method described herein is intended to be construed as requiring its steps to be performed in a specific order. Therefore, if a method claim does not actually describe the order in which its steps are followed, and it is not otherwise explicitly stated in the claims or description that the steps should be limited to a specific order, it is not intended to be inferred in any way of order. This applies to all possible implicit grounds for interpretation, including logical matters relating to the structure of the steps or operational flow, the obvious meanings derived from grammatical construction or punctuation, and the number or type of embodiments described herein.

[0020] The following description will include specific details to enable a complete understanding. Nevertheless, those skilled in the art will understand that the apparatus, system, and associated methods of using the apparatus can be implemented and used without using these specific details. In fact, the apparatus, system, and associated methods can be implemented by modifying the illustrated apparatus, system, and associated methods and can be used in conjunction with any other apparatus and techniques conventionally used in industry.

[0021] Tumor Therapeutic Field (TTF) therapy is a proven technique for treating tumors using alternating current (AC) electric fields at frequencies between 50 kHz and 1 MHz. The AC electric field can be induced by transducer arrays (e.g., arrays of capacitively coupled electrodes) placed on either side of the target body. When an AC voltage is applied between opposing transducer arrays, an AC current is coupled through the transducer array into the target body. In some embodiments, the frequency of the AC voltage can be between 50 kHz and 1 MHz or between 100 kHz and 500 kHz.

[0022] This specification discloses a system for applying TTF to a portion of the body 102 of object 100, with reference to Figures 1 to 6 in various embodiments. As described herein, the body 102 of object 100 may include any part of the object, for example, the head 104, torso 106, or limbs (e.g., upper arms 108, thighs 110). The system 10 may comprise a carrier 12 having a carrier body 14 that defines a receiving space 16.

[0023] The electrical signal generator 20 can be at least partially received within the receiving space 16 of the carrier body 14. In some cases, the electrical signal generator 20 can be fully received within the receiving space 16 of the carrier body 14. In further embodiments, the electrical signal generator 20 can be partially received within the receiving space 16 of the carrier body 14. The receiving space 16 can be configured to tightly receive the electrical signal generator 20 so as not to move. For example, the electrical signal generator 20 can be elongated (for example, in some cases, generally cylindrical and elongated along the height of the cylinder), and the receiving space 16 can be elongated longitudinally to receive the electrical signal generator 20. In any further embodiment, the receiving space 16 can have internal retaining straps that secure (in some cases permanently secure) the electrical signal generator 20 within the receiving space.

[0024] The carrier 12 may further include a coupling device 26 configured to fixate the carrier body 14 to a first position on the body 102 of the subject 100. In various embodiments, the first position may be the thigh 110, part of the torso 106 (e.g., the waist 112, chest 114, or armpit 116), or the upper arm 108 of the body 102 of the subject 100. In some arbitrary embodiments, the coupling device may be configured to hold the carrier body 14 in close contact with the subject's body. Thus, in some arbitrary embodiments, the carrier body 14 cannot move relative to the subject's body without the subject intentionally moving the carrier body (e.g., it cannot move more than 5 cm in any direction). In this way, the position of the carrier body 14 can remain substantially fixed to the body during daily activities. This differs from conventional carriers that are held by hand or loosely attached to the body and are designed to be put down or removed during normal activities such as sitting in a chair or otherwise transitioning between sitting and standing.

[0025] In various embodiments, the coupling device 26 may comprise a belt 30, a strap 32, and / or a sleeve 34. In some arbitrary embodiments, the coupling device 26 may comprise a clip, buckle, hook-and-loop fastener, or other fastener 28. The clip, buckle, hook-and-loop fastener material, or other fastener 28 may be configured to allow the coupling device 26 to be selectively fastened in a loop configuration or an open configuration. In further arbitrary embodiments, the coupling device 26 may comprise a strap adjuster configured to adjust the operating length of the coupling device (e.g., the circumference of the belt, strap, or sleeve). In some cases, the clip, buckle, hook-and-loop fastener material, or other fastener 28 may function as the strap adjuster.

[0026] It is conceivable that the coupling device 26 may, in some cases, be elastic (for example, to allow stretching). In a further embodiment, the coupling device 26 may be inelastic.

[0027] In one embodiment, the coupling device 26 may include a belt 30 configured to extend around the torso 106 of the subject. For example, the belt 30 may be configured to extend around the subject's waist 112 (e.g., at a position below the subject's ribs and on the subject's buttocks or at a position above the buttocks). Thus, in some embodiments, the carrier 12 may be positioned at or above the waist 112 of the subject 100. For example, in some arbitrary embodiments, the carrier body 14 may be positioned at the lower back of the subject, on one side of the buttocks, or at the front of the pelvis. In further embodiments, the belt 30 may extend around the subject's chest 114 (e.g., around or across the subject's ribs). When in use, the carrier 12 may be positioned sufficiently high (relative to the waist) so that the carrier (and device) does not come into contact with the subject's legs when the subject transitions from a standing to a sitting position.

[0028] Referring to Figures 2 and 3, in a further embodiment, the coupling device 26 may include a strap 32 configured to extend around the thigh 110 of the subject. Thus, the carrier body 14 may be positioned to the side or front of the thigh 110.

[0029] Referring to Figure 6, in a further embodiment, the coupling device 26 may include a strap 32 configured to position the carrier body 14 within the chest or armpit (and above the waist) of the target, extending over the target's shoulder and under the armpit on the opposite side of the target. Also, referring to Figures 8A and 8B, the carrier body 14 can be positioned under the target's armpit and / or at least partially within the armpit. For example, in some embodiments, the coupling device 26 may include a torso strap 32a extending around the target's torso (above the waist) to hold the carrier body 14 in contact with the target's torso. The coupling device 26 may further include at least one shoulder strap 32b extending over at least one shoulder of the target to distribute at least a portion of the weight of the carrier body 14 to the shoulder. In some arbitrary embodiments, the shoulder strap 32b may be coupled to the torso strap 32a at first and second attachment points to the front and rear of the carrier body 14, respectively. In a further embodiment, the shoulder strap 32b may be coupled to the carrier body 14.

[0030] Referring to Figures 9A and 9B, in some arbitrary embodiments, the carrier body 14 can be positioned on the chest of the subject. For example, the coupling device 26 may include a torso strap 32a extending around the torso of the subject (above the waist) and holding the carrier body 14 in contact with the torso of the subject. The coupling device 26 may further include a first shoulder strap 32b extending over the subject's first shoulder and distributing at least a portion of the weight of the carrier body 14 to the first shoulder. The coupling device 26 may further include a second shoulder strap 32b extending over the subject's second shoulder and distributing at least a portion of the weight of the carrier body 14 to the second shoulder. The first ends of the first and second shoulder straps 32b can be coupled to the torso strap 32a, and the second ends of the first and second shoulder straps can optionally be coupled to either the carrier body 14 or the torso strap 32a.

[0031] In some cases, the carrier body 14 may be configured such that, when worn by the subject during use, the entire body is held above the subject's lowest ribs. In some cases, the carrier body may be configured such that, when worn by the subject during use, the entire body is held below the subject's neck.

[0032] Referring to Figure 6, in a further embodiment, the coupling device 26 may include a sleeve 34. In some cases, the sleeve 34 may be configured to extend around the thigh 110 of the subject. In a further embodiment, the sleeve 34 may be configured to extend around the upper arm 108 of the subject.

[0033] In some embodiments, as shown in Figure 2, the carrier 12 may include a belt 30 configured to extend around the waist of the subject's body. In some cases, the carrier housing 14 may hang down from the belt 30 via a suspension strap 94 (Figure 10A). In some cases, the length of the suspension strap 94 may be adjustable. The carrier may further include straps 32 configured to extend around the thighs of the subject's body. For example, at least one strap 32 (e.g., an upper strap and a lower strap as shown) may connect the carrier body to the thigh. In this way, the majority of the carrier's weight can be supported by the subject's waist, and the straps around the thigh can hold the carrier body in contact with the thigh.

[0034] Furthermore, the belt 30, strap 32, or sleeve 34 can surround a body part (e.g., the subject's legs, torso, or arms), and the carrier body 14 can be moved around the body part (without detaching the coupling device from the subject) to adjust the position of the carrier body for different situations and environments. For example, as described, the carrier 12 can be attached around the subject's waist. In some situations (e.g., while walking), it may be advantageous for the carrier body 14 to be in a first position (e.g., positioned on the lower back of the subject), and in further situations (e.g., while sitting), it may be advantageous for the carrier body to be in a second position (e.g., in front of the subject's buttocks or pelvis). Thus, the carrier 12 can allow the subject to change the position of the carrier body 14 between the first and second positions. Similarly, in various embodiments, the carrier body 14 can be positioned in front of, to the side of, behind, or on the inside of the subject's thighs. For example, referring to Figures 10A and 10B, in some embodiments, the carrier body 14 can be attached to a first position 90 on the outside of the subject's thigh. In some embodiments, this position (on the outside of the thigh to avoid contact with the other thigh) may be advantageous for walking, etc. In some embodiments, the carrier body 14 can be moved from the first position 90 to a second position 92 on the front of the subject's thigh. In some embodiments, this position (on the front of the thigh) may be advantageous when sitting in a chair with armrests, which may, in some cases, contact the carrier body 14 at the first position on the outside of the thigh. In some embodiments, both the carrier body 14 and the coupling device 26 (e.g., belt 30 and strap 32) can move together (e.g., rotate together relative to the subject) to move the carrier body 14 to and between the first and second positions 90, 92. In further embodiments, the carrier body 14 can move (e.g., slide) relative to at least a portion of the coupling device 26.For example, in some embodiments, the suspension strap 94 can be attached to the belt 30 via a loop 96, thereby allowing the loop to slide along the length of the belt. In some cases, the carrier body can be made movable around the thigh along the length of the strap 32. In further embodiments, the carrier body and the strap 32 can move around the thigh simultaneously.

[0035] In various arbitrary embodiments, the carrier body 14 can be positioned on one of the following: the chest, underarm, upper arm, or thigh. For example, in some cases, the carrier body 14 can be positioned on the chest so that the carrier body is generally above the rib cage and generally below the neck (see, for example, Figures 9A and 9B). In further embodiments, the carrier body 14 can be positioned on the chest so that when the subject is seated, the carrier body is positioned above the subject's thigh. In some cases, the carrier body can be positioned sufficiently low under the armpit so as not to interfere with arm movement (see, for example, Figures 8A and 8B). For example, the carrier body 14 can be configured to be positioned below the subject's pectoralis major muscle when worn.

[0036] One or more transducer arrays 22 can be positioned on the body 102 of the subject 100. For example, one or more transducer arrays 22 can be positioned on or within the head 104 of the subject. In a further embodiment, the transducer arrays can be positioned on the torso 106 of the subject 100 (for example, for the treatment of lung cancer) or on other parts of the subject's body. One or more transducer arrays 22 can communicate with an electrical signal generator 20 via at least one electrical cable 24. Each of the transducer arrays 22 may comprise one or more transducers configured to emit a TTF in response to a signal provided by the electrical signal generator 20. One or more transducer arrays 22 can be positioned on the body 102 of the subject 100 at a second location different from the first location.

[0037] The second location can be close to the treatment site. For example, without limitation, the second location can be on the head 104 of the subject 100. In exemplary embodiments, the second location can be the top of the head, the front of the head, the back of the head, the sides of the head, or an area including parts thereof. For example, the transducer array can cover at least a portion of the top, front, back, and sides of the subject's head, as shown in Figure 1. In further embodiments, the second location can be on the torso of the subject. For example, the second location can be on the front, back, or sides of the torso. In further embodiments, the transducer array 22 can be at any location on the subject's body.

[0038] In a further embodiment, each transducer array 22 may be in its own second position, each second position being different from the first position. For example, each second position on the body may be on both sides of the head (e.g., the left and right sides, as well as the front and back of the head). In a further embodiment, each second position on the body may be on the torso (e.g., the front and back of the torso). In a further embodiment, the second position of at least one transducer array 22 may be on the torso of the body of the subject, and the second position of at least one additional transducer array 22 may be on the head of the body of the subject.

[0039] In some cases, as shown in several embodiments, referring to Figures 1 and 5A, the system 10 may include an electrical junction box 40. The electrical junction box 40 can enable electrical communication (and physical coupling) between one or more transducer arrays 22 and electrical signal generators 20. For example, in some embodiments, at least one electrical cable 24 may comprise a first electrical cable 42 that extends between the electrical signal generators 20 and the electrical junction box and couples with the electrical signal generators 20 and the electrical junction box. Each second electrical cable (e.g., electrical cables 44a, 44b, 44c) may extend between each transducer array 22 (e.g., transducer arrays 22a, 22b, 22c) and couple with each transducer array 22. In this way, the electrical junction box 40 can act as a junction box that enables each electrical signal generator 20 to supply different electrical signals to each different transducer array 22.

[0040] Referring to Figures 1 and 5A and 5B, in some embodiments, the electrical junction box 40 may have a first side 46 and a second side 48 opposite to it. The first side 46 may define a first port 50 that connects to a first electrical cable 42, and the second side 48 may define at least one second port 52 that connects to a second electrical cable (e.g., electrical cables 44a, 44b, 44c). In some embodiments, at least one electrical cable may be integrated with the electrical junction box 40. For example, the first electrical cable 42 may be integrated with the electrical junction box 40 through the first port 50, or it may be permanently physically coupled to the electrical junction box 40. In further embodiments, both the first port 50 and the second port 52 may be on the same first side 46 of the electrical junction box. In this way, all electrical cables can extend from the electrical junction box in the same direction, thereby allowing the electrical junction box 40 to be inserted into the receiving space so that all electrical cables exit through a single opening in the carrier body 14 without any significant bending (e.g., more than 90°) occurring in any of the electrical cables. In a further embodiment, the electrical junction box 40 can be omitted, and the electrical cables 24 can extend directly from the electrical signal generator 20 to the transducer array 22.

[0041] In some arbitrary embodiments, the electrical junction box 40 can be coupled to the carrier 12. For example, the system 10 may include a clip 53 for coupling the electrical junction box to the carrier 12. In some arbitrary embodiments, the clip 53 can coupling the electrical junction box 40 to a belt 30 or other coupling device 26. In some cases, the clip 53 may include a member that is deflected by a torsion spring 55 by rotating relative to the surface (for example, of the electrical junction box 40). In some embodiments, the coupling device 26 may define a loop 57 (Figure 4) that can receive the clip 53.

[0042] In various further embodiments, the electrical junction box 40 can be received within the carrier 12. For example, in some cases, the electrical junction box 40 can be received within the receiving space 16. In any further embodiment, the receiving space 16 can be a first receiving space, and the carrier 12 can define a second receiving space 51. In some embodiments, the carrier 14 can comprise at least a first carrier body 14a and a second carrier body 14b, where the first carrier body defines a first receiving space 16 and the second carrier body defines a second receiving space 51. In further embodiments, the carrier body 14 can define both the first receiving space 16 and the second receiving space 51. In some cases, the electrical junction box 40 can be received within the second receiving space 51. In further embodiments, the carrier can define at least one pocket 70 (Figure 4). In some cases, the pocket 70 can be separated from the receiving space 16.

[0043] Referring to Figures 10A and 10B, in some embodiments, the carrier body 14 may have an inner surface 60 and an outer surface 62. The inner surface 60 of the carrier body 14 may define a receiving space 16. In some arbitrary embodiments, the carrier body 14 may further define at least one opening 64 extending between the inner surface 60 and the outer surface 62. The opening 64 may communicate with the receiving space of the carrier body and may be configured to allow heat to dissipate from the electrical signal generator 20. In some embodiments, the carrier body may define a single opening 64. In further embodiments, the carrier body may define two, three, four, or five or more openings 64. In various arbitrary embodiments, the openings 64 may be, for example, on the sides of the carrier body 14 and / or on the bottom of the carrier body. In some cases, a permeable cover such as a grid, screen, or perforated material may cover one or more openings 64, while allowing air to pass through.

[0044] Referring to Figures 9A and 9B, in further embodiments, the carrier 12 may include a cover 66 coupled to a carrier body 14 and extending over at least a portion of the receiving space 16 of the carrier body. The cover 66 can prevent liquids or other undesirable elements (e.g., food crumbs, dust, etc.) from entering the receiving space. For example, in some embodiments, the carrier body may define a top opening 68 that allows an electrical signal generator to be inserted into and removed from the carrier, and the cover 66 may extend across the top opening when in the closed position 84. In some cases, the cover 66 may be pivotably coupled to the carrier body 14 (e.g., via a hinge or flexible joint). In further embodiments, the cover may be coupled to the carrier body via any suitable fastener 80 (e.g., a zipper or one or more buttons, clips, etc.) to hold the cover 66 in the closed position 84. In some arbitrary embodiments, the cover 66 may be held in the open position 86. For example, the carrier 12 may include a fastener 82 (e.g., hook-and-loop fastener material, a snap, or one or more magnets) that holds the cover 66 in the open position 86. In any further embodiment, the cover 66 may be spring-biased toward the open position 86 or locked in the open position via a mechanical catch that can be released. In some cases, the cover 66 may include a lip 88 that extends downward from the top opening 68 relative to the vertical axis when the cover 66 is in the closed position 84.

[0045] In various embodiments, the carrier body 14 may define at least one coupling element 72 that can be attached to and detached from there of different coupling devices. The coupling element 72 may comprise, for example, a loop into which a strap 30 or belt 32 can be inserted. In any further embodiment, the coupling element 72 may comprise one hook-and-loop fastener configured to engage with a carabiner, a clip (e.g., a double-sided release buckle) and / or the other hook-and-loop fastener of the coupling device 26.

[0046] Conventional electrical signal generator carriers resemble suitcases and are designed to be removed from a person during general daily activities. Unlike such conventional electrical signal generator carriers, the carrier 12 disclosed herein is configured to remain attached to a person during daily activities such as sitting, standing, walking, and exercising. Thus, the length of the electrical cables can be shortened to the length necessary to allow unrestricted movement of the subject without having extra length that could cause tripping or snagging. For example, the maximum length of the electrical cable 24 can be 20 cm or less, exceeding the distance from the carrier to the electrode array furthest from the carrier, measured along the path to the subject's body. In embodiments with an electrical junction box 40, the length of the electrical cable 24 can be the sum of the length of the first electrical cable 42, the length of the (longest) second electrical cable, and the distance between the first port 50 and the second port 52. By shortening the length of the electrical cables compared to conventional systems, the weight of the electrical cables can be further reduced. In further embodiments, the extra cable length can be accommodated within the carrier 12. For example, in some embodiments, the excess length of the cable can be received in a first receiving space 16. In further embodiments, the excess length of the cable can be received in a second receiving space 52. In further embodiments, the system may include at least one retaining strap (or band or wire tie) configured to secure the excess cable length in a winding configuration, a folded configuration, or a bundled configuration. For example, the excess length of the cable can be folded once or more to define a plurality of adjacent cable segments, and the retaining strap can be wrapped around the plurality of adjacent cable segments. In some embodiments, the retaining strap may include a fastener (e.g., a hook-and-loop fastener material, snap fastener, or clip that holds the retaining strap in a loop configuration). In further embodiments, the retaining strap may include a semi-rigid member (e.g., similar to a twist tie) that allows the retaining strap to remain wrapped around the excess length of the cable.In some cases, the retaining strap can be attached to the carrier 12. In a further embodiment, the retaining strap can be separated from the carrier 12 and is not attached to the carrier 12.

[0047] In some embodiments, the kit may comprise a carrier body 14 as disclosed herein and a plurality of coupling devices 26. In some embodiments, each of the coupling devices 26 can be selectively attached to or detached from the carrier body 14. In this way, the subject can select different coupling devices depending on the desired position of the coupling devices and the carrier body.

[0048] The electrical signal generator 20 is thought to be equipped with a portable power source such as a battery. A spare battery 74 can be placed in one of the carrier's pockets 70. The spare battery 74 can be used to replace the depleted battery of the electrical signal generator 20.

[0049] Embodiments disclosed herein can enable subjects undergoing TTF therapy to move and be active between treatments. For example, unlike conventional suitcase-like carriers, the carrier 12 does not need to be picked up and held. Therefore, the subject is not required to constantly pay attention to the position of the carrier. Furthermore, embodiments disclosed herein can be more practical compared to conventional suitcase-like carriers. For example, the carrier 12 can have a much more discreet appearance that is less conspicuous than conventional carriers. Moreover, in some arbitrary embodiments, the carrier 12 can be worn under clothing, and electrical cables can similarly extend under clothing, thereby making the system 10 little to no visible to bystanders.

[0050] How to use The carrier 12 described herein can be fixedly attached to the body of the object 100 in a first position. For example, a strap can be positioned across at least a portion of the torso of the object's body, across at least the upper arm of the object's body, or around the thigh of the object's body. In a further embodiment, a belt can be positioned around the torso of the object's body. In a further embodiment, a sleeve can be positioned around the upper arm or thigh of the object. The electrical signal generator 20 can be positioned within the receiving space 16 of the carrier body 14 of the carrier 12.

[0051] Each transducer array 22 can be reliably positioned at a second location on the target body, where the first location is different from the second location.

[0052] In some cases, each transducer array of a plurality of transducer arrays can be positioned at its respective second position before the carrier is fixedly coupled to a first position in the body. In some arbitrary embodiments, the second position can be determined by a computing device 1001. For example, the computing device 1001 can instruct the subject or clinician to appropriately position each transducer array. The computing device can receive information about the area to be treated (for example, via clinician input), such as the location of a tumor in the body. Based on the patient's position and biostructure, the computing device can determine the appropriate positioning for each transducer array and provide an output indicating the appropriate positioning for each transducer array.

[0053] In any further embodiment, the computing device 1001 can determine at least one placement location on the subject's body where the carrier can be fixedly coupled to avoid any overlap of any part of the multiple transducer arrays. In some embodiments, based on the placement of the transducer arrays, the computing device can provide locations for positioning the carrier body 14 so that it is separated from the transducer arrays (for example, so that the transducer arrays are not located between the carrier body and the subject). In this way, excessive heat at one location on the subject's body can be minimized. For example, in an embodiment where the placement of the transducer arrays is on the subject's chest, the computing device can recommend the armpit, upper arm, or thigh of the subject's body as a location for positioning the carrier body 14. The computing device can communicate with a display, which can provide the display with an output indicating placement locations on the body where the carrier can be fixedly coupled to avoid any overlap of any part of the multiple transducer arrays. For example, the display can output a list or graphic of locations. The computing device may further provide an output indicating which coupling device can be used to securely attach the carrier to the body at the above-mentioned placement location.

[0054] In some cases, the computing device 1001 can determine at least one placement location on the body of a subject where carriers can be fixedly coupled, avoiding overlap of any part of the multiple transducer arrays, using the determined appropriate positioning of each transducer array. In a further embodiment, the computing device can receive user input of the position of each transducer array to determine at least one placement location on the body of a subject where carriers can be fixedly coupled, avoiding overlap of any part of the multiple transducer arrays. For example, the computing device can provide a prompt (e.g., on a display) for the user to input the position of each transducer array, and the user (e.g., a clinician) can input the position of each transducer array via an input device of the computing device.

[0055] The transducer array 22 can be coupled to the electrical signal generator 20. For example, in some arbitrary embodiments, the second electrical cables of each transducer array (e.g., electrical cables 44a, 44b, 44c) can be coupled to an electrical junction box, and the electrical signal generator 20 can be coupled to the electrical junction box 40 via the first electrical cable 42, thereby enabling electrical communication between the electrical signal generator and the transducer array. In various embodiments, the electrical junction box 40 can be clipped to a carrier (e.g., to a belt 32) or positioned within a carrier (e.g., within a receiving space 16).

[0056] An electrical signal generator 20 can be used to supply an electrical signal to a transducer array 22, which can then generate TTF. U.S. Patent No. 7,565,205, granted July 21, 2009, is incorporated herein by reference in whole and provides further details on generating and using TTF to treat cancer.

[0057] In some embodiments, the supply of electrical signals to the transducer array 22 can be stopped. In some cases, after supplying electrical signals while the carrier is coupled to the object using a first coupling device, the carrier can be coupled to the object using a different coupling device. For example, the coupling device can be detached from the object's body. Initially, the coupling device can be coupled to the object's body using a first coupling device, and the carrier can also be coupled to the object's body using a second coupling device different from the first coupling device. In some cases, the first coupling device can be detached from the carrier body before the second coupling device is coupled to the carrier body (so that the first and second coupling devices are coupled to the carrier body in sequence). In some cases, the second coupling device can be used to position the carrier in a third position different from the first and second positions. In exemplary embodiments, the second coupling device may differ from the first coupling device in terms of fastener type, coupling position, and / or size.

[0058] Computing devices Figure 7 shows a system 1000 including an exemplary configuration of a computing device 1001 used with the system 10 disclosed herein. In some embodiments, the computing device 1001 can be integrated with the system 10. In further embodiments, the computing device 1001 may be a separate computing device, such as a tablet, smartphone, laptop, or desktop computer, which may be able to communicate with the system 10 and enable the subject to interface with the system 10.

[0059] The computing device 1001 may include one or more processors 1003, a system memory 1012, and a bus 1013 that connects various components of the computing device 1001, including one or more processors 1003, to the system memory 1012. In the case of multiple processors 1003, the computing device 1001 may utilize parallel computing.

[0060] Bus 1013 may comprise one or more of several possible types of bus structures, such as a memory bus, memory controller, peripheral bus, accelerated graphics port, and processor or local bus, using any of the various bus architectures.

[0061] The computing device 1001 may operate on and / or be equipped with various computer-readable media (e.g., non-temporary). The computer-readable media may be any available media accessible by the computing device 1001, and include non-temporary media, volatile media, and / or non-volatile media, removable media, and non-removable media. The system memory 1012 has computer-readable media in the form of volatile memory, such as random-access memory (RAM), and / or non-volatile memory, such as read-only memory (ROM). The system memory 1012 may store data such as transducer position data 1007 (i.e., data from signals received by electrodes), and / or program modules such as an operating system 1005 and positioning software 1006, which are accessible to and run by one or more processors 1003.

[0062] The computing device 1001 may also include other removable / non-removable, volatile / non-volatile computer storage media. The mass storage device 1004 may provide non-volatile computer code, computer-readable instructions, data structures, program modules, and other data for the computing device 1001. The mass storage device 1004 may be a hard disk, removable magnetic disk, removable optical disk, magnetic cassette or other magnetic storage device, flash memory card, CD-ROM, digital versatile disk (DVD) or other optical storage, random access memory (RAM), read-only memory (ROM), electrically erasable programmable read-only memory (EEPROM), etc.

[0063] Any number of program modules may be stored on the mass storage device 1004. The operating system 1005 and the location software 1006 may be stored on the mass storage device 1004. One or more operating systems 1005 and location software 1006 (or any combination thereof) may comprise the program modules and the location software 1006. The transducer location data 1007 may also be stored on the mass storage device 1004. The transducer location data 1007 may be stored in one or more databases known in the art. The database may be centralized or distributed across multiple locations within the network 1015.

[0064] The user may input commands and information to the computing device 1001 using input devices (not shown). Such input devices include, but are not limited to, keyboards, touchscreen displays, pointing devices (e.g., computer mouse, remote control), microphones, joysticks, scanners, tactile input devices such as gloves, and other body coverings, motion sensors, and voice recognition. These input devices and other input devices may be connected to one or more processors 1003 using a human-machine interface 1002 coupled to bus 1013, or they may be connected by other interfaces and bus structures such as parallel ports, game ports, IEEE 1394 ports (also known as FireWire ports), serial ports, network adapters 1008, and / or general-purpose serial buses (USB).

[0065] The display device 1011 may also be connected to the bus 1013 using an interface such as a display adapter 1009. The computing device 1001 may have multiple display adapters 1009, and the computing device 1001 may have multiple display devices 1011. The display device 1011 may be a monitor, an LCD (liquid crystal display), a light-emitting diode (LED) display, a television, a smart lens, smart glasses, and / or a projector. In addition to the display devices, other output peripheral devices may include components such as a speaker (not shown) and a printer (not shown) that can be connected to the computing device 1001 using an input / output interface 1010. Any step and / or result of the method may be output to (or made to be output to) an output device in any form. Such output may be any form of visual representation, including but not limited to text, graphics, animation, audio, and haptics. The display 1011 and the computing device 1001 may be part of a single device or may be separate devices.

[0066] The computing device 1001 may operate in a networked environment using a logical connection to one or more remote computing devices 1014a, 1014b, 1014c. The remote computing devices 1014a, 1014b, 1014c may be personal computers, computing stations (e.g., workstations), portable computers (e.g., laptops, mobile phones, tablet devices), smart devices (e.g., smartphones, smartwatches, activity trackers, smart apparel, smart accessories), security and / or surveillance devices, servers, routers, network computers, peer devices, edge devices, or other common network nodes. The logical connection between the computing device 1001 and the remote computing devices 1014a, 1014b, 1014c may be formed using a network 1015 such as a local area network (LAN) and / or a general-purpose wide area network (WAN), or a cloud-based network. Such a network connection may be formed via a network adapter 1008. The network adapter 1008 may be implemented in both wired and wireless environments. Such networked environments are conventional and prevalent in homes, offices, enterprise-wide computer networks, intranets, and the internet. Remote computing devices 1014a, 1014b, and 1014c may, in some cases, have some or all of the components disclosed as part of computing device 1001. In various further embodiments, some or all of the data processing described herein may be performed via cloud computing on one or more servers or other remote computing devices. Thus, at least a portion of system 1000 can be configured using internet connectivity.

[0067] Exemplary aspects In view of the products, systems, and methods described herein, as well as variations thereof, some more detailed embodiments of the present invention will be described below. However, these detailed embodiments should not be construed as having a limiting effect on any different claim, each containing different or more general teachings, nor should any “specific” embodiment be construed as being limited in any way other than in the inherent meaning of the language used literally herein.

[0068] Embodiment 1: A system for applying a tumor treatment electric field to a portion of a target body, comprising: a carrier having a carrier body defining an acceptance space; a coupling device configured to fixally connect the carrier body to a first position on the target body, the first position being one of the thigh, chest, upper arm, or armpit of the target body; an electrical signal generator at least partially accepted within the acceptance space of the carrier body; and at least one transducer array electrically in contact with the electrical signal generator, wherein each transducer array of the at least one transducer array is configured to be reliably positioned at a second position on the target body, the second position being at least one transducer array different from the first position.

[0069] Embodiment 2: The coupling device comprises a strap, the system according to Embodiment 1.

[0070] Embodiment 3: The coupling device comprises a belt, the system according to Embodiment 1.

[0071] Embodiment 4: The coupling device comprises a sleeve, the system according to Embodiment 1.

[0072] Embodiment 5: The system according to Embodiment 1, wherein the coupling device comprises a belt and a strap coupled to a carrier body and belt, and extending between the carrier body and the belt.

[0073] Embodiment 6: The system according to any one of embodiments 1 to 5, further comprising an electrical cable enabling electrical communication between an electrical signal generator and at least one transducer array.

[0074] Embodiment 7: The system according to any one of embodiments 1 to 5, further comprising an electrical junction box, a first electrical cable enabling electrical communication between an electrical signal generator and the electrical junction box, and at least a second electrical cable enabling electrical communication between the electrical junction box and at least one transducer array.

[0075] Embodiment 8: The system according to Embodiment 7, wherein the coupling device comprises a belt and a strap coupled to a carrier body and the belt, and extending between the carrier body and the belt.

[0076] Embodiment 9: The system according to Embodiment 8, further comprising a clip for attaching an electrical junction box to a belt.

[0077] Embodiment 10: The system according to Embodiment 8, wherein the electrical junction box is at least partially received within the receiving space of the carrier body.

[0078] Embodiment 11: The system according to Embodiment 7, wherein the carrier further comprises a second receiving space, the second receiving space at least partially receiving an electrical junction box.

[0079] Embodiment 12: The system according to Embodiment 2, wherein the strap is configured to be positioned across at least a portion of the torso of the subject's body.

[0080] Embodiment 13: The system according to Embodiment 2, wherein the strap is configured to be positioned around the upper arm of the subject's body.

[0081] Embodiment 14: The system according to Embodiment 2, wherein the strap is configured to be positioned around the thigh of the subject's body.

[0082] Embodiment 15: The system according to Embodiment 3, wherein the belt is configured to be positioned around a portion of the torso of the subject's body.

[0083] Embodiment 16: The system according to Embodiment 4, wherein the sleeve is configured to be positioned around the upper arm of the subject's body.

[0084] Embodiment 17: The system according to Embodiment 4, wherein the sleeve is configured to be positioned around the thigh of the subject's body.

[0085] Embodiment 18: The system according to Embodiment 7, wherein the electrical junction box has opposing first and second sides, the first side of the electrical junction box defines a first electrical port and a second electrical port, the first electrical cable is coupled to the first electrical port, and the second electrical cable is coupled to the second electrical port.

[0086] Embodiment 19: The system according to any one of Embodiments 1 to 18, wherein the carrier body has an inner surface and an outer surface, the inner surface of the carrier body defines a receiving space, the carrier body further defines an opening extending between the inner surface and the outer surface, the opening communicating with the receiving space of the carrier body and configured to allow heat from an electrical signal generator to dissipate.

[0087] Embodiment 20: The system according to any one of Embodiments 1 to 19, wherein the carrier further comprises a cover coupled to a carrier body and extending over at least a portion of the receiving space of the carrier body.

[0088] Embodiment 21: The system according to any one of Embodiments 1 to 20, wherein the carrier body further defines at least one pocket separated from the receiving space of the carrier body.

[0089] Embodiment 22: A kit comprising a carrier having a carrier body defining a receiving space, a plurality of coupling elements configured to be selectively and detachably coupled to the carrier body, and an electrical signal generator at least partially received within the receiving space of the carrier body, and at least one transducer array electrically communicating with the electrical signal generator, wherein the at least one transducer array is configured to be reliably positioned at a second location on the body of a subject, the second location being different from a first location, and each coupling element of the plurality of coupling elements is configured to allow coupling of the carrier body to different locations on the body of a subject.

[0090] Embodiment 23: The kit according to Embodiment 22, wherein the multiple connecting elements comprise at least one of a strap, a belt, or a sleeve.

[0091] Embodiment 24: A method comprising the steps of: fixing a carrier to a first location on a body of a target, wherein the carrier comprises a carrier body defining an acceptance space, wherein an electrical signal generator is at least partially accepted within the acceptance space; and a coupling device fixing the carrier body to a first location on a body of a target; reliably positioning each transducer array of at least one transducer array at a respective second location on a body of a target, wherein the second location is different from the first location, and at least one transducer array is electrically in contact with an electrical signal generator; supplying an electrical signal to at least one transducer array using the electrical signal generator; and generating a tumor therapeutic electric field using at least one transducer array.

[0092] Embodiment 25: The method according to Embodiment 24, wherein the coupling device comprises a strap.

[0093] Embodiment 26: The method according to Embodiment 24, wherein the coupling device comprises a belt.

[0094] Embodiment 27: The method according to Embodiment 24, wherein the coupling device comprises a sleeve.

[0095] Embodiment 28: The method according to Embodiment 24, wherein the coupling device comprises a belt and a strap coupled to a carrier body and the belt and extending between the carrier body and the belt, and the method further includes the step of positioning the belt of the coupling device around the user's waist.

[0096] Embodiment 29: The method according to Embodiment 24, wherein an electrical cable enables electrical communication between an electrical signal generator and at least one transducer array.

[0097] Embodiment 30: The method according to Embodiment 24, wherein an electrical signal generator is electrically coupled to an electrical junction box using a first electrical cable, and at least one transducer array is electrically coupled to an electrical junction box using at least a second electrical cable, thereby enabling electrical communication between the electrical signal generator and at least one transducer array.

[0098] Embodiment 31: The method according to Embodiment 30, wherein the coupling device comprises a belt and a strap coupled to a carrier body and the belt and extending between the carrier body and the belt, and the method further includes the step of positioning the belt of the coupling device around the user's waist.

[0099] Embodiment 32: The method according to Embodiment 31, further comprising the step of attaching an electrical junction box to a belt using a clip.

[0100] Embodiment 33: The method according to Embodiment 31, wherein the electrical junction box is at least partially received within the receiving space of the carrier body.

[0101] Embodiment 34: The method according to Embodiment 30, further comprising the steps of coupling a secondary carrier to a carrier body and positioning at least a portion of an electrical junction box within the secondary carrier receiving space.

[0102] Embodiment 35: The method according to Embodiment 25, further comprising the step of positioning the strap across at least a portion of the torso of the subject's body.

[0103] Embodiment 36: The method according to Embodiment 25, further comprising the step of positioning the strap around the upper arm of the subject's body.

[0104] Embodiment 37: The method according to Embodiment 25, further comprising the step of positioning the strap around the thigh of the subject's body.

[0105] Embodiment 38: The method according to Embodiment 26, further comprising the step of positioning the belt around a portion of the torso of the subject's body.

[0106] Embodiment 39: The method of Embodiment 27, further comprising the step of positioning the sleeve around the upper arm of the body of the subject.

[0107] Embodiment 40: The method according to Embodiment 27, further comprising the step of positioning the sleeve around the thigh of the body of the subject.

[0108] Embodiment 41: The method according to Embodiment 30, wherein the electrical junction box has opposing first and second sides, the first side of the electrical junction box defines a first electrical port and a second electrical port, a first electrical cable is coupled to the first electrical port, and a second electrical cable is coupled to the second electrical port.

[0109] Embodiment 42: The method according to any one of Embodiments 24 to 41, wherein the carrier body has an inner surface and an outer surface, the inner surface of the carrier body defines a receiving space, the carrier body further defines an opening extending between the inner surface and the outer surface, the opening communicating with the receiving space of the carrier body and dissipating heat from the electrical signal generator.

[0110] Embodiment 43: The method according to any one of Embodiments 24 to 42, further comprising the step of positioning a cover over at least a portion of the receiving space of a carrier body, wherein the cover is coupled to the carrier body.

[0111] Embodiment 44: The method according to any one of Embodiments 24 to 43, further comprising the step of positioning a spare battery in a pocket of the carrier body.

[0112] Embodiment 45: The method according to any one of Embodiments 24 to 44, further comprising the steps of: stopping the supply of electrical signals to at least one transducer array; detaching a coupling device from the body of object; and coupling a second coupling device to the carrier body and the body of object, wherein the second coupling device is different from the coupling device.

[0113] Embodiment 46: The method according to Embodiment 45, wherein the second coupling device is coupled to the body of the object at a position different from the first position.

[0114] Embodiment 47: The method according to Embodiment 46, wherein each of the coupling device and the second coupling device comprises a strap, belt, sleeve, or a combination thereof.

[0115] Embodiment 48: The method according to Embodiment 45, further comprising the step of detaching the coupling device from the carrier body.

[0116] Embodiment 49: The method according to any one of Embodiments 24 to 48, wherein at least one transducer array comprises a plurality of transducer arrays, each transducer array of the plurality of transducer arrays is positioned at a second position before a carrier is fixedly coupled to a first position on a body, and the method further comprises the steps of: using a computing device to determine the second position; using a computing device to determine at least one placement position on a body of target to which the carrier can be fixedly coupled so as to avoid any overlap of any part of the plurality of transducer arrays; and using a computing device or a display associated with a computing device to provide an output indicating the at least one placement position.

[0117] Embodiment 50: A carrier used in conjunction with an electrical signal generator disclosed herein.

[0118] Although the above invention has been described in some detail through illustrations and embodiments for the purpose of clarity of understanding, some changes and modifications may be made within the scope of the appended claims. [Explanation of symbols]

[0119] 10 Systems 12 carriers 14. Carrier body 14a The main carrier of the first carrier 14b The second carrier 16 Acceptance Space 20 Electrical signal generator 22, 22a, 22b, 22c transducer arrays 24 Electrical Cables 26 Coupling device 28 Fastener 30 belts 32 straps 32a Torso strap 32b Shoulder strap 34 sleeves 40 Electrical junction box 42 First electrical cable 44a, 44b, 44c electrical cables 46 First side 48. The second side 50 First port 51. The second acceptance space 52 Second port 53 clips 55 Torsion spring 57 loops 60 Inner self 62 Exterior 64 openings 66 Cover 68 Top opening 70 pockets 72 connecting elements 74 Spare batteries 80 Fastener 82 Fastener 84 Closed position 86 Open position 88 Lip 90 First position 92 Second position 94 Suspension Straps 96 loops 100 targets 102 Body 104 Head 106 Torso 108 Upper arm 110 Thigh 112 Waist 114 Chest 116 Underarm 1000 System 1001 Computing Devices 1002 Human-Machine Interface 1003 Processor 1004 Mass storage devices 1005 Operating Systems 1006 Position determination software 1007 Transducer position data 1008 Network Adapter 1009 Display Adapter 1010 Input / Output Interface 1011 Display Devices 1012 System Memory 1013 Bus 1014a, 1014b, 1014c Remote Computing Devices 1015 Network

Claims

1. A system for applying a tumor treatment electric field to a part of the target body, The carrier body defines the receiving space, A carrier having a coupling device configured to fix the carrier body to a first position on the body of the target, wherein the first position is one of the thigh, chest, upper arm, or armpit of the body of the target, An electrical signal generator, at least partially received within the receiving space of the carrier body, At least one transducer array that is electrically in contact with the electrical signal generator, Each transducer array of the at least one transducer array is configured to be reliably positioned at each second location on the body of the subject, and each second location is different from the first location and comprises at least one transducer array, Electrical junction box and A first electrical cable that enables electrical communication between the electrical signal generator and the electrical junction box, A second electrical cable enabling electrical communication between the electrical junction box and the at least one transducer array, Equipped with, The carrier further comprises a second receiving space, the second receiving space at least partially receiving the electrical junction box, in a system.

2. The coupling device comprises a strap, and the strap is Crossing at least a portion of the torso of the body of the subject, or Around the upper arm of the body of the aforementioned object The system according to claim 1, configured to be positioned.

3. The coupling device comprises a belt, according to claim 1.

4. The coupling device comprises a sleeve, and the sleeve is Around the upper arm of the body of the subject, or Around the thigh of the body of the subject The system according to claim 1, configured to be positioned.

5. The coupling device is belt and, The system according to claim 1, comprising a carrier body and a belt, and a strap extending between the carrier body and the belt.

6. The system according to claim 1, further comprising an electrical cable enabling electrical communication between the electrical signal generator and the at least one transducer array.

7. The coupling device is belt and, A strap is connected to the carrier body and the belt, and extends between the carrier body and the belt, The electrical connection box is connected to the belt by a clip, The system according to claim 1, comprising:

8. The system according to claim 7, wherein the electrical junction box is at least partially received within the receiving space of the carrier body.

9. The system according to claim 3, wherein the belt is configured to be positioned around a portion of the torso of the body of the target.

10. The system according to claim 1, wherein the electrical junction box has opposing first and second sides, the first side of the electrical junction box defines a first electrical port and a second electrical port, the first electrical cable is coupled to the first electrical port, and the second electrical cable is coupled to the second electrical port.

11. The system according to claim 1, wherein the carrier body has an inner surface and an outer surface, the inner surface of the carrier body defines the receiving space, the carrier body further defines an opening extending between the inner surface and the outer surface, the opening communicates with the receiving space of the carrier body and is configured to allow heat from the electrical signal generator to dissipate.

12. The system according to any one of claims 1 to 11, A kit comprising at least a second coupling device configured to be selectively and detachably coupled to the carrier body, wherein each coupling device and the second coupling device comprises a second coupling element configured to allow coupling of the carrier body to different positions on the body of the object.

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