Personal care composition containing bio-surfactants

Abstract

A sulfate-free personal care composition comprising a rhamnolipid surfactant provides good cleansing and foaming properties. The rhamnolipid surfactant has a single rhamnose head group (i.e., mono-rhamnolipid) and a single lipid tail group (i.e., monolipid). The single lipid tail group has a carbon chain length of 10 to 13. The composition may contain one or more additional surfactants selected from anionic surfactants, amphoteric surfactants, zwitterionic surfactants, nonionic surfactants, cationic surfactants, and combinations thereof, as long as the additional surfactant does not contain sulfate. The composition also contains a dermatologically acceptable carrier.

Description

[Technical Field]

[0001] This disclosure relates to sulfate-free personal care compositions, generally comprising glycolipid surfactants. More specifically, this disclosure relates to sulfate-free personal care compositions comprising surfactants having a single rhamnose head group and a single C10-C13 alkyl tail group. [Background technology]

[0002] Human hair becomes dirty due to contact with the surrounding environment and sebum secreted by the scalp. Dirty hair can have an undesirable feel and / or appearance. As a result, people may wash their hair with shampoo compositions that restore it to a clean and attractive appearance. Many conventional shampoos use sulfated surfactants, such as sodium lauryl sulfate and / or sodium laureth sulfate, to cleanse the hair. While sulfated surfactants are generally very good at removing oil and other contaminants from hair, they also have drawbacks. For example, sulfated surfactants can sometimes lead to a poor quality hair feel after washing, dry hair, and / or dry skin. This is commonly referred to as "harshness," and harsh shampoos are generally unacceptable to consumers.

[0003] Removing the sulfated surfactant provides a less irritating cleansing composition, but particularly has drawbacks for conditioning shampoos (i.e., shampoos that provide cleansing and conditioning effects to the hair). Conditioning shampoos having a surfactant system based on sulfate generally use a cationic conditioning polymer to form a coacervate with the sulfate-based surfactant during use, which provides the foaming / lathering properties desired by consumers. However, non-sulfated surfactants tend to be less effective at forming coacervates with the conditioning polymer as a sulfated surfactant, which can result in non-smooth lathering, washing, and conditioning effects. Also, certain cationic conditioning polymers may introduce instability to products using a surfactant system that does not contain sulfate. In particular, a second phase known as the surfactant-polymer coacervate can form in the composition rather than forming during use as needed (in situ coacervate). The formation of in situ coacervates is typically perceived by consumers as an undesirable cloudy product or a product having a precipitate layer with inferior performance during use.

[0004] There is also a demand by consumers and manufacturers of cleansing compositions for more environmentally friendly compositions. Surfactants used in conventional cleansing compositions are generally recognized as being derived from petrochemical products that are environmentally unfriendly. However, sustainability in the use of cosmetic ingredients has become increasingly important and is being demanded by more consumers and manufacturers of cosmetic cleansing agents. The use of certain sustainable or natural-derived surfactants is well known. Glycolipids are one such example of a natural-derived surfactant.

[0005] Glycolipids are found in the cell membranes of eukaryotes, where they play a structural role and facilitate many other cellular functions. Glycolipid surfactants generally consist of a glycosyl head and a lipid tail, which provides the amphiphilic behavior commonly exhibited by surfactants. However, natural-derived surfactants such as glycolipids may not provide the amount of foaming and cleaning performance desired by consumers. For example, U.S. Patent No. 10,292,924 discloses the need for a cleaning composition containing ramnolipids with good foam properties. According to its description, the cleaning composition of U.S. Patent No. 10,292,924 addresses this problem by providing a high concentration of di-ramnolipids relative to mono-ramnolipids.

[0006] In contrast, European Patent No. 2,410,039 discloses a cleaning composition characterized by a ratio of mono-ramnolipids to di-ramnolipids of 95:5 to 45:55. European Patent No. 2,410,039 also discloses that ramnolipids are anionic surfactants that may be optionally mixed together to provide desirable foaming properties. In particular, European Patent No. 2,410,039 suggests that ramnolipids with two short fatty acids are more effective in reducing surface tension and are more active as emulsifiers, while these rare ramnolipids with a single fatty acid chain are less effective. European Patent No. 2,410,039 indicates that the major mono-ramnolipid and di-ramnolipid components expressed by bacteria generally need to be extracted and re-blended to provide suitable detergency. Therefore, there is still a need for mild cleaning compositions that use natural-derived surfactants to provide desirable foam and cleaning properties.

Prior Art Documents

Patent Documents

[0007]

Patent Document 1

Patent Document 2

Summary of the Invention

[0008] Therefore, it is desirable to provide a personal cleansing composition containing naturally derived surfactants and exhibiting desirable foaming and cleaning properties. It is also desirable to provide such a composition that does not contain sulfated surfactants. It is even more desirable to provide such a composition that exhibits good stability. [Means for solving the problem]

[0009] Rha-C 10 , Rha-C 11 , Rha-C 12 , Rha-C 13 Disclosed herein are personal care compositions comprising a rhamnolipid surfactant selected from and combinations thereof, an additional surfactant selected from anionic surfactants, amphoteric surfactants, bipolar surfactants, nonionic surfactants, cationic surfactants, and combinations thereof, and a carrier. The personal care compositions do not contain sulfated surfactants. [Brief explanation of the drawing]

[0010] [Figure 1] This shows the foaming height characteristics exhibited by various combinations of glycolipid surfactants. [Modes for carrying out the invention]

[0011] Shampoos containing sulfated surfactants are generally recognized as providing desirable cleansing properties, including the removal of sebum and dirt, as well as good lathering. However, sulfated surfactants are generally perceived as harsh. Replacing sulfated surfactants with naturally derived surfactants, such as glycolipid surfactants, may provide a milder clean, but may not provide the desired amount of foam and / or cleansing. Surprisingly, it has now been found that certain types of rhamnolipid surfactants can provide suitable foaming and cleansing. In particular, certain mono-rhamno-monolipid surfactants were found to provide better foaming and cleansing properties than conventional rhamnolipid surfactant homologs having two or more lipid tail groups.

[0012] References to “embodiments” in this specification mean that certain materials, features, structures, and / or properties described in relation to that embodiment are included in at least one embodiment, and optionally many embodiments, but not that all embodiments incorporate the described materials, features, structures, and / or properties. Furthermore, materials, features, structures, and / or properties may be combined in any preferred manner across different embodiments, and materials, features, structures, and / or properties may be excluded from or substituted for those described. Accordingly, the embodiments and aspects described herein may include or be combined with elements or components of other embodiments and / or aspects, even if they are not explicitly illustrated in combination, unless otherwise stated or described as incompatible.

[0013] All ingredient percentages described herein are by weight of the cosmetic composition unless otherwise specified and may be expressed as "weight % (wt%)". Unless otherwise specified, all ratios are by weight. All ranges include endpoints and are combinable. Significant digits do not represent limitations on the stated quantity or on the precision of the measurement. Unless otherwise specifically indicated, all quantities are understood to be modified by the word "about". Unless otherwise specified, all measurements are understood to have been made under ambient conditions of approximately 25°C, where "ambient conditions" means conditions of approximately 1 atmosphere and approximately 50% relative humidity. All number ranges encompass narrower ranges, and the upper and lower limits of the specified ranges are interchangeable to create further unspecified ranges.

[0014] The compositions of the present invention may include, may essentially consist of, or may consist of the essential components and optional components described herein. As used herein, "consisting essentially of" means that the composition or component may include additional components, but only if the additional components do not substantially alter the basic and novel properties of the claimed composition or method. As used herein and in the appended claims, the singular forms "a," "an," and "the" are intended to include the plural form unless the context clearly indicates otherwise.

[0015] definition The term "approximately" modifies a specific value by indicating a range of ±20% or less of the stated value (for example, ±15%, ±10%, or ±5%).

[0016] As used in relation to compositions, "apply" or "application" means to apply or spread the composition onto the stratum corneum surface of a human body, such as skin or hair.

[0017] Charge density (CD) refers to the ratio of positive charges to the molecular weight of a polymer.

[0018] A "cleansing composition" refers to a personal care composition or product intended for use in washing the body surface, such as skin or hair. Some non-exclusive examples of cleansing compositions include shampoos, conditioners, conditioning shampoos, shower gels, liquid hand cleansers, and facial cleansers.

[0019] "Cosmetic agent" means any substance, or any component thereof, intended to be rubbed, poured, sprinkled, sprayed, introduced, or otherwise applied to the body or any part thereof of a mammal in order to produce a cosmetic effect. Cosmetic agents may contain substances and food additives that are generally recognized as safe (GRAS) by the U.S. Food and Drug Administration.

[0020] The term "gel network phase" or "dispersed gel network phase" refers to a layered or vesicular solid crystalline phase comprising at least one aliphatic alcohol, at least one gel network surfactant, and a liquid carrier. The layered or vesicular phase may be formed as alternating layers, with one phase comprising the aliphatic alcohol and gel network surfactant and the other phase comprising the liquid carrier.

[0021] "Solid crystalline" refers to the crystalline structure of a layered or vesicular phase at ambient temperature, caused by a phase below its melting transition temperature. For example, the melting transition temperature of a layered or vesicular phase may be about 30°C or higher (i.e., slightly above room temperature). The melting transition temperature can be measured by differential scanning calorimetry, a conventional measurement method well known to those skilled in the art.

[0022] "Suitable for application to human hair" means that the personal care composition or its components are acceptable for use in contact with human hair, scalp, and skin without excessive toxicity, incompatibility, instability, allergic reactions, etc.

[0023] "Substantially free of" means that the composition or component contains less than 3% by weight of the subject material (e.g., less than 2% by weight, less than 1% by weight, or less than 0.5% by weight). "Free of" means that the composition or component contains 0% of the subject material.

[0024] A "sulfated surfactant" refers to a surfactant that contains sulfate components. Some non-specific examples of sulfated surfactants include sodium lauryl sulfate, sodium laureth sulfate, ammonium lauryl sulfate, and ammonium laureth sulfate. A "sulfate-free surfactant" refers to a surfactant that does not contain sulfate components.

[0025] Personal care composition The sulfate-free personal care compositions described herein comprise a mono-rhamno-mono-lipid surfactant and, optionally, one or more additional non-sulfating surfactants and / or other components commonly found in compositions of the type described herein. The personal care compositions described herein may be provided in various product forms, such as solutions, suspensions, shampoos, conditioners, lotions, creams, gels, toners, sticks, sprays, aerosols, ointments, cleansing liquids, solid bars, pastes, foams, mousses, shaving creams, wipes, strips, patches, hydrogels, film-forming products, facials, and skin masks (with and without insoluble sheets). The form of the composition may depend on a selected dermatologically acceptable specific carrier. In some embodiments, the personal care compositions described herein may include a dispersed gel reticular structure phase, in combination with a cleansing glycolipid surfactant, that provides a less irritating but effective cleansing effect on soiled hair.

[0026] For example, the composition may contain less than 1% (e.g., 0% to 0.8%, 0.05% to 0.5%, or 0.1% to 0.3%) of inorganic salts, such as sodium chloride, potassium chloride, sodium sulfate, ammonium chloride, sodium bromide, or combinations thereof. In some conventional cleaning compositions, inorganic salts are added to thicken the product. However, in sulfate-free cleansing compositions, inorganic salts can introduce instability into the composition by assisting in the formation of coacervates between commonly present anionic surfactants and cationic polymers. Coacervates typically have a gel-like viscosity and can affect the rheological and performance properties of the composition, as well as the quality of the product as perceived by consumers.

[0027] Maintaining a desired salt concentration may reduce or eliminate the problem of product instability associated with in situ coacervate formation. Therefore, in some embodiments, it may be important to avoid or minimize the addition of extra inorganic salts as carryover components (i.e., trace components that may be present in other components added to the composition). For example, commercially available sulfate-free surfactants such as glutamate-based, betaine-based, and sultaine-based surfactants generally contain high concentrations of inorganic salts (e.g., 5% or more). Product instability may manifest as a cloudy appearance, phase separation, and / or precipitation. Methods for determining the presence or absence of in situ coacervates are well known in the art, for example, as described in U.S. Patent No. 2023 / 0118201.

[0028] Naturally, it should be recognized that when a cleaning composition is used as intended (i.e., diluted with water), it forms a coacervate and provides the desired cleaning effect.

[0029] Rhamnolipid surfactants The personal care compositions described herein include one or more rhamnolipid bio-surfactants to provide foaming and cleansing advantages to personal care compositions for cleaning targeted body surfaces such as soiled hair and skin. The rhamnolipid surfactants herein may be produced by microorganisms (e.g., Pseudomonas aeruginosa, Pseudomonas putida, Pseudomonas chlororaphis). Rhamnolipid surfactants facilitate cleaning due to their amphiphilic properties, which allow the surfactant to break down and form micelles around oils and other contaminants in the hair. The "entrapped" contaminants can then be more easily washed away with water. Descriptions of various types of rhamnolipids are disclosed in European Patent No. 2410039. Methods for producing, extracting, and blending naturally occurring rhamnolipids are well known in the art.

[0030] The rhamnolipid surfactants used herein are mono-rhamnose-mono-lipid surfactants, in which case a single lipid tail has a length of 10 to 13 carbon atoms, for example, according to the formula shown below ("Rha-C"). 10~13 )]

[0031] [ka] In the formula, R is an alkyl group having 10 to 13 carbon atoms.

[0032] Conventional knowledge has held that rhamnolipids with a single lipid tail are generally unsuitable for use as surfactants due to their low cleansing power, particularly compared to conventional rhamnolipids with two lipid tails. However, it has now been discovered that mono-rhamnolipids with a single fatty acid tail of 10-13 carbon atoms exhibit surprisingly good foaming and cleansing properties when added to personal cleansing compositions. Therefore, the personal cleansing compositions herein contain 0.1%-10% (e.g., 0.5%, or 1%-5%) of Rha-C 10~13 The compositions may contain surfactants. In some embodiments, the compositions herein may contain additional surfactants. In such embodiments, Rha-C 10~13 Surfactants may constitute 1% to 80% (for example, 3% to 50%) of the total surfactants in the composition.

[0033] Additional surfactants The personal care compositions described herein may optionally further include one or more non-sulfating surfactants. The additional surfactants may be selected from anionic surfactants, such as isethionate, sarcosinate, sulfonate, sulfosuccinate, sulfoacetate, glycinate, glutamate, glucose carboxylate, and phosphate ester surfactants; cationic surfactants such as polyquaternium surfactants; amphoteric / bipolar surfactants, such as surfactants broadly described as derivatives of aliphatic secondary and tertiary amines, where one aliphatic substituent contains 8 to 18 carbon atoms and one aliphatic substituent contains an anionic group such as a carboxyl group, sulfonate group, phosphate group, or phosphonate group; nonionic surfactants such as polyethylene oxide condensates of alkylphenols; and combinations thereof. Some non-limiting examples of any of the above surfactants are disclosed in U.S. Patents 20190105246, 20180098923, 9271908, International Publication No. 2020 / 016097, and McCutcheon's Emulsifiers and Detergents, 2019, MC Publishing Co.

[0034] Some particularly preferred examples of additional surfactants include amphoteric surfactants, e.g., cocoamphoacetate, cocoamphodiaacetate, lauroamphoacetate, lauroamphodiaacetate, amidebetaine, amidesulfobetaine, hydroxysultaine, and mixtures thereof, as well as anionic surfactants, e.g., isethionate, sarcosinate, sulfonate (e.g., alpha-olefin sulfonate), taurate, alaninate, glycinate, glutamate, sulfosuccinate, and mixtures thereof.

[0035] Optional additional surfactants, if present, may be included in the personal care composition to provide the desired cleaning and foaming properties. Any additional surfactants must be physically and chemically compatible with the other components of the personal care composition described herein and must not excessively impair the stability, aesthetics, or performance of the product. In some embodiments, additional surfactants may be present in the personal care composition at concentrations of 5% to 50% (e.g., 8% to 30%, 9% to 25%, or 10% to 17%).

[0036] Dispersed gel reticular structure phase The personal care compositions described herein may include a dispersed gel reticular structure phase in combination with a cleansing surfactant to provide a suitable cleansing effect to the composition. The gel reticular structure phase can impart a cleansing effect to the personal care composition due to its hydrophobicity. Specifically, although not bound by theory, it is thought that the hydrophobic properties of the dispersed gel reticular structure cause the gel reticular structure to dissolve hydrophobic dirt such as oil into the gel reticular structure. Once the dirt is dissolved in the gel reticular structure, the gel reticular structure can be rinsed off from the hair or skin.

[0037] A suitable dispersed gel network structure can be formed by combining an aliphatic alcohol and a gel network structure surfactant in a suitable ratio and heating the dispersion to a temperature above the melting point of the aliphatic alcohol. During this mixing process, the aliphatic alcohol melts, distributing the gel network structure surfactant and allowing water to be incorporated into the aliphatic alcohol. Mixing the gel network structure surfactant and the aliphatic alcohol also transforms droplets of isotropic aliphatic alcohol into droplets of a liquid crystalline phase. Subsequently, when the mixture is cooled to a temperature below the melting transition temperature of the aliphatic alcohol, the liquid crystal phase is converted into a solid crystalline gel network structure. Further details of suitable gel reticular structures are described in GMEccleston, "Functions of Mixed Emulsifiers and Emulsifying Waxes in Dermatological Lotions and Creams," Colloids and Surfaces A: Physiochem. and Eng. Aspects 123-124 (1997) 169-182; and in GM Eccleston, "The Microstructure of Semisolid Creams," Pharmacy International, Vol. 7, 63-70 (1986), each incorporated herein by reference.

[0038] In some embodiments, it may be desirable to pre-form a gel reticular structure phase, meaning that at least 50 percent of the mixture of aliphatic alcohol, gel reticular structure surfactant, and liquid carrier is substantially in a solid crystalline phase before being added to the other components of the personal care composition. When a dispersed gel reticular structure is pre-formed, the gel reticular structure components may be prepared as a separate premix, which, after cooling, can then be incorporated together with the cleansing surfactant and any other components of the personal care composition. While not theoretically bound, it is believed that incorporating pre-formed gel reticular structure components with the cleansing surfactant and other components of the personal care composition will result in the formation of a substantially equilibrium layered dispersion (ELD) in the final composition.

[0039] ELD is a dispersed, layered, or vesicular phase obtained from a pre-formed gel reticular structure component that is substantially equilibrated with a cleansing surfactant, a carrier, and other optional components of the personal care composition. This equilibration occurs when the pre-formed gel reticular structure component is incorporated into the other components of the personal care composition and can be effectively completed within approximately 24 hours after incorporation. If the component containing the gel reticular structure component (i.e., aliphatic alcohol, gel reticular surfactant, and liquid carrier) is added as individual components together with the other components of the personal care composition in a single mixing step, and not as a separate pre-formed gel reticular structure component, then ELD will not be formed.

[0040] The presence of a gel reticular structure in premixes and personal care compositions can be confirmed by means well known to those skilled in the art. For example, the gel reticular structure can be identified using X-ray analysis, optical microscopy, electron microscopy, and differential scanning calorimetry. Preferred X-ray analysis methods are described in U.S. Patent Application Publication No. 2006 / 0024256, which are incorporated herein by reference.

[0041] In some embodiments, the scale size of the dispersed gel reticular structure in the personal care composition may be in the range of about 10 nm to about 500 nm (e.g., 0.5 μm to 10 μm or 10 μm to about 150 μm).

[0042] The scale size distribution of the dispersed gel reticular structure in the personal care composition can be measured by laser scattering technique using a Horiba Model LA910 laser scattering particle size distribution analyzer (Horiba Instruments, Inc., Irvine, California, USA). The scale size distribution in the personal care composition is measured using 1.75 g of the personal care composition and 30 mL of 3% NH4Cl and 20 mL of 2% Na2HPO4. . The measurement can be performed by forming a mixture of 7H2O and 10 mL of 1% Laureth-7. This mixture is then stirred for 5 minutes. Depending on the individual Horiba instrument used, a sample ranging from 1 to 40 mL is taken and then injected into a Horiba instrument containing 75 mL of 3% NH4Cl, 50 mL of 2% Na2HPO4.7H2O, and 25 mL of 1% Laureth-7 until the index of the Horiba instrument reaches 88-92%T, which is required for scale size measurement. Once this is achieved, after 2 minutes of circulation, the measurement is performed through the Horiba instrument, yielding a scale size measurement. Subsequent measurements are performed using a sample of the personal care composition heated to a temperature above the melting transition temperature of all fatty substances present in the shampoo composition to ensure that the dispersed gel reticular tissue components are melted. Subsequent measurements provide the scale size distribution for all remaining substances in the personal care composition, which can then be compared to the scale size distribution of the initial sample to aid in the analysis.

[0043] Gel reticular tissue aliphatic alcohol The dispersed gel network structure may contain an aliphatic alcohol (e.g., C10 - C40 aliphatic alcohol) at 0.05% by weight or more of the composition (e.g., 0.05% - about 25% by weight, 0.5% - 20% by weight, or 1% - 8% by weight). The aliphatic alcohol may be linear or branched and may be saturated or unsaturated. As can be understood, suitable aliphatic alcohols may be of natural, plant, or synthetic origin. In some embodiments, in order to provide a dispersed gel network structure phase having a melting transition temperature of about 38°C or higher, it may be desirable to mix several aliphatic alcohols, such as a mixture of cetyl alcohol and stearyl alcohol in a ratio of 20:80 - 80:20. Some non - limiting examples of aliphatic alcohols suitable for use herein include cetyl alcohol, stearyl alcohol, arachidyl alcohol, behenyl alcohol, C 21 aliphatic alcohol (1 - heneicosanol), C 23 aliphatic alcohol (1 - tricosanol), C 24 aliphatic alcohol (lignoceryl alcohol, 1 - tetracosanol), C 26 aliphatic alcohol (1 - hexacosanol), C 28 aliphatic alcohol (1 - octacosanol), C 30 aliphatic alcohol (1 - triacontanol), C 20~40 alcohol (e.g., Performacol® 350 Alcohol and 425 Alcohol available from New Phase Technologies), C 30~50 alcohol (e.g., Performacol® 550 Alcohol), C 40~60 alcohol (e.g., Performacol® 700 Alcohol), and mixtures thereof.

[0044] Gel network structure surfactant The gel network phase may be present in an amount of 0.01% to 15% by weight of the composition (e.g., 0.1% to about 10% by weight, 0.2% to about 5% by weight). The gel network surfactant may be combined with an aliphatic alcohol and a liquid carrier to form a gel network premix, which can then be added to the other components of the personal care composition.

[0045] In some embodiments, the total weight of the gel network surfactant and the aliphatic alcohol is 0.5% to about 15% by weight (e.g., 1% to 10% by weight) of the personal care composition. In some embodiments, the gel network surfactant may be included in the gel network in a desired weight ratio relative to the aliphatic alcohol. For example, the ratio of aliphatic alcohol to gel network surfactant may be 1:5 to 100:1 (e.g., 1:1 to 40:1, 2:1 to 20:1, or 3:1 to 10:1).

[0046] The gel network surfactant may be any suitable anionic surfactant, dipolar surfactant, amphoteric surfactant, cationic surfactant, or nonionic surfactant that is substantially sulfate-free. The detergent surfactant and the gel network surfactant may be independently selected and may be the same or different. In some embodiments, the gel network surfactant has hydrophobic end groups having a chain length of 10 to 40 carbon atoms. The hydrophobic end groups may be alkyl, alkenyl (containing up to three double bonds), alkyl aromatic, or branched alkyl. Mixtures of more than one gel network surfactant may also be used. Some non-limiting examples of gel network surfactants are disclosed in U.S. Patent Application Publication No. 2006 / 0024256.

[0047] Liquid carriers for gel reticular tissue phases In some embodiments, the dispersed gel reticular structure phase may contain a suitable liquid carrier in an amount of 0.05% to 95% by weight of the personal care composition. The liquid carrier may be water or another suitable solvent. The carrier and the gel reticular structure surfactant may be selected to act together to swell the aliphatic alcohol, which results in the formation and stability of the gel reticular structure phase. Suitable solvents are any solvent that can be used in place of or in combination with water in the formation of the gel reticular structure phase. In some embodiments, the liquid carrier may be substantially free of solvents other than water. In some embodiments, the liquid carrier for the dispersed gel reticular structure phase may be included in a weight ratio of about 1:1 to the aliphatic alcohol of the dispersed gel reticular structure phase.

[0048] Carrier Liquid Carrier The personal care compositions of this specification may contain 20% to 95% (e.g., 60% to about 85%) of a liquid carrier. The liquid carrier can be separated from the liquid carrier of the dispersed gel network phase. The type and amount of liquid carrier should be selected to provide a composition having the desired rheological properties. The liquid carrier may be water, or a miscible mixture of water and an organic solvent. In some embodiments, the liquid carrier may be water containing little or no organic solvent (e.g., 5%, 3%, 1%, 0.5%, or less than 0%). Suitable organic solvents include aqueous solutions of lower alkyl alcohols and polyhydric alcohols. Useful lower alkyl alcohols include monohydric alcohols having 1 to 6 carbon atoms, such as ethanol and isopropanol. Exemplary polyhydric alcohols include propylene glycol, hexylene glycol, glycerin, and propanediol.

[0049] Other optional components The personal care compositions described herein may contain various optional components to adjust the properties and characteristics of the composition to suit the purpose, as needed. The optional components may be well-known materials commonly found in this type of composition. The optional components should be physically and chemically compatible with the essential components of the personal care composition and should not otherwise impair stability, aesthetics, or performance of the composition. The individual concentrations of the optional components may generally range from about 0.001% to about 10% by weight of the personal care composition.

[0050] Non-limiting examples of other optional components that may be included in the personal care compositions herein include: co-surfactants, deposition aids, cationic polymers, conditioning agents (including hydrocarbon oils, fatty esters, and silicones), anti-dandruff agents, antimicrobial agents, suspending agents, viscosity modifiers, dyes, pigments, non-volatile solvents or diluents (water-soluble and insoluble), pearlescent agents, foaming agents, lice killers, pH adjusters, fragrances, preservatives, chelating agents, proteins, vitamins, amino acids, skin surfactants, sunscreens, UV absorbers, stabilizers, and combinations thereof.

[0051] multiphase composition In some embodiments, the personal care composition may be in the form of a multiphase composition. For example, the first phase of the composition may contain conventional personal care ingredients such as structured surfactants, and the second phase may contain a beneficial phase. A method for producing a multiphase personal care composition is disclosed in U.S. Patent No. 8,653,014.

[0052] Method for preparing personal care compositions The personal care compositions described herein may be prepared using conventional methods for producing compositions of a desired type (e.g., shampoo, conditioner, or body wash). In some embodiments, the composition may be prepared by (a) combining an aliphatic alcohol, a gel reticular surfactant, and water at a temperature sufficient to form a premix, where the secondary surfactant and water can be partitioned into the aliphatic alcohol; (b) cooling the premix to below the chain dissolution temperature of the aliphatic alcohol to form a gel reticular structure; and (c) adding the gel reticular structure to one or more cleansing surfactants and a liquid carrier to form a personal care composition comprising a dispersed gel reticular structure phase having a melting transition temperature of at least about 38°C.

[0053] In some embodiments, the gel reticular structure phase can be prepared by heating and mixing an aliphatic alcohol, a gel reticular structure surfactant, and water to a level ranging from about 75°C to about 90°C. This mixture can then be cooled to 27–35°C (for example, by passing the mixture through a heat exchanger). As a result of this cooling step, at least about 50 percent of the mixture of aliphatic alcohol and gel reticular structure surfactant crystallizes to form a crystalline gel reticular structure.

[0054] Another method for preparing the gel reticular structure phase involves reducing the particle size of the dispersed gel reticular structure phase by sonicating and / or grinding the components of an aliphatic alcohol, a gel reticular structure surfactant, and water while heating them. This increases the surface area of ​​the gel reticular structure phase, and the gel reticular structure surfactant and water cause the gel reticular structure phase to swell. Another variation for preparing the gel reticular structure involves first heating and mixing an aliphatic alcohol and a gel reticular structure surfactant, and then adding this mixture to water.

[0055] How to use The personal care compositions described herein may be used in conventional ways for cleansing and conditioning hair or skin. The effective amount of composition for use is generally in the range of 1 g to 50 g (e.g., 1 g to about 20 g). Generally, the method of treating hair or skin may involve applying the personal care composition to the hair or skin. For example, an effective amount of the personal care composition may be applied to water-soaked hair or skin, and then the composition may be rinsed off. Application to hair usually involves moving the composition through the hair so that most or all of the hair is in contact with the composition. The personal care compositions may be used as liquids, solids, semi-solids, flakes, or gels in a pressurized container with added propellants, or in the form of a pump spray. The viscosity of the product may be selected to correspond to the desired form.

[0056] In some embodiments, a method for treating hair or skin may include (a) wetting the hair or skin with water; (b) applying an effective amount of the personal care composition to the hair or skin; and (c) rinsing the applied area of ​​skin or hair with water. These steps may be repeated any number of times as desired to achieve the desired cleansing and conditioning effect.

[0057] method Blender foaming volume method This method can be used to evaluate the foaming properties that consumers associate with the quality of shampoo products. This method is described in detail in Klein, Ken, "Evaluating Shampoo Foam," Cosmetic & Toiletries, Vol. 119, No. 10, pp. 32-35, 2004.

[0058] Add 1 gram of shampoo product to 39 grams of deionized water (DI water) at room temperature. Carefully pour this solution into a Magic Bullet MB1001 blender (or equivalent) at single speed to minimize the introduction of bubbles and mix for 10 seconds. Next, pour the bubbles into a 250 mL graduated cylinder and measure and record the volume of bubbles. Optionally, after 3.5 minutes, the bubbles' stability can be assessed by recording the position of the bubbles / water interface (discharge). In this method, the discharging of bubbles explains the flow of liquid through the bubbles resulting from the weakening of the bubbles. Higher bubbles discharging rates correspond to more unstable bubbles.

[0059] Method for achieving foam height and creaminess The foaming ability of shampoo does not directly affect the physical behavior of hair fibers. However, the foam of shampoo can affect the user's perception or hair characteristics. In some cases, it may be useful to distinguish between lather and foam for shampoo evaluation. In particular, foam can generally refer to a mass of bubbles in a liquid film matrix, while lathering, more specifically, refers to the type of foaming that is formed during shampooing and other processes, where foam consists of small bubbles that are densely packed and therefore resist flow.

[0060] This method provides a way to simulate the foam produced by surfactants when used on hair under typical shampooing conditions and to quantify specific foam properties. Oil (e.g., sebum) and dirt are two of the most common contaminants found on hair that can undesirably affect the foam properties of shampoo. Therefore, this method can be used to evaluate the effect of oil and dirt on the properties of foam.

[0061] Oil foaming height method and foaming cream method Add 100 mL of water (at 100°F) to a suitable blender (e.g., a KitchenAid KSB560CU1 brand food mixer or equivalent), followed by 2 mL of the test composition and 1 mL of extra virgin olive oil. Mix the mixture while "stirring" for 30 seconds and record the foam height in mm.

[0062] To evaluate creaminess, the foam is poured into a suitable bowl and visually inspected. Based on the visual inspection, the creaminess of the foam is rated on a scale of 0 to 5, where 0 is not creamy at all (poor) and 5 is very creamy (good).

[0063] Dirt foaming height method Pour 300 mL of water (at 100°F) into a suitable blender (e.g., KitchenAid KSB560CU1 brand food mixer or equivalent), then add 3 mL of the test composition and 2 grams of potting soil (e.g., MIRACLE GRO brand potting soil or equivalent). Mix the mixture for 15 seconds while stirring, and record the foam height in mm.

[0064] In-Lab Screening (ILS) method for wet hair This method can be used to determine the cleansing and / or conditioning properties of a hair care composition. In this method, 20 g of Caucasian Low Lift Hair Tresses (International Hair Importers and Products, Inc., Glendale, New York, USA) is moistened with water, treated with the test composition, and placed in an ILS sink. The sink has a salon spray head / hose that is held in place, but can be directed to direct water onto strands of hair hanging from a rod positioned above the sink. The strands can be added to and removed from the water as needed. The water is maintained at a temperature of approximately 38°C and a flow rate of approximately 5.7 liters / minute. The method is as follows: Calibrate the ILS sink to 38°C. • Place the hair bundle / hairpiece on the rod in the sink. • Wet the hair strands completely for 30 seconds. Using your index and middle fingers ("scissor fingers"), squeegee the hair strands once from top to bottom to remove excess water ("squeegeeing" means clamping the strands at the top between your index and middle fingers and stroking them down once to remove the water). Apply a 0.1g / g (product / hair) test composition to the front surface of the hairpiece from top to bottom. After squeezing the hairpiece for 15 seconds, flip the hairpiece over so the bottom is facing upwards and squeeze for another 15 seconds. "Squeezing (milking)" means grasping the top of the bundle and stroking it downwards, creating a lather with alternating hands. • Evaluate the slipperiness during application (within the first 5 strokes). Start from the top of the ponytail, just below where the hair lies flat. Slide your fingers from top to bottom. Your fingers may slow down due to resistance to skipping the hairpiece. Scale: 0 = no slipperiness ~ 10 = very slippery. • Evaluate the creaminess of the foam (appearance and feel, after 30 seconds of whipping). Scale: 0 = not creamy ~ 10 = very creamy. Optionally, compare with blender-generated foam creaminess. • Evaluate the ease of combing (is there still foam in the hairpiece?). Using minimal pressure, comb through the hair from beginning to end (starting from the top), and using minimal force, comb through the entire hairpiece (combing from top to bottom). Scale: 0 = difficult to comb ~ 10 = easy to comb. Rinse for 30 seconds (while gently squeezing the hairpiece). • Evaluate the smoothness during rinsing (average rating during rinsing). Scale: 0 = no slipperiness ~ 10 = very slippery. • Use the fingers of the scissors to squeegee the hairpiece bundle once. • Evaluate the smoothness after rinsing. Wipe once and evaluate the feel. Scale: 0 = No slipperiness ~ 10 = Very slippery. • Evaluate the cleanliness after rinsing. Gently stroke the hair from top to bottom with moderate pressure between your thumb and two fingers. Judge how clean or dirty the hair feels. Scale: 0 = Low (dirty) ~ 10 = High (clean). • Evaluate combability after rinsing. Using the lowest possible pressure, comb from the beginning to the end of the hair (from front to back) with the widest teeth side, and then comb through the entire hairpiece (from top to bottom) with the least amount of force. Scale: 0 = stiff ~ 10 = easy. [Examples]

[0065] Example 1: Example of shampoo formulation and surfactant performance This example provides exemplary formulations of the rhamnolipid surfactants specified herein and demonstrates their ability to provide suitable foaming and cleaning performance. Comparative compositions and compositions of the present invention were tested for their ability to provide good foam volume, height, and creaminess, which are well known as shampoo properties. The shampoo properties, summarized in Table 3, were measured according to the method described above.

[0066] Table 1 provides five examples of comparative shampoo formulations (C1-C5) and six examples of shampoo formulations of the present invention (Inv 1-6). Comparative Example 1 is a conventional sulfate-free shampoo composition that does not contain glycolipid surfactants. Comparative Examples C2-C5 each contain a commercially available di-rhamno-di-lipid surfactant mixture. Examples 1-6 of the present invention contain a mono-rhamno-mono-lipid surfactant (Rha-C 10 , Rha-C 11 , Rha-C 12 , or Rha-C 13 ) includes. Example 4 of the present invention is Rha-C 10 , Rha-C 12 The composition also includes a mixture of di-rhamno-di-lipid surfactants used in C2 and C3. The amounts of rhamnolipid surfactants shown in Table 1 represent the amount of active substance present in the composition.

[0067] The compositions in Table 1 can be prepared by adding deionized water to a mixing vessel and heating to 75°C ± 3°C while stirring. For compositions C1, C2 and Inv 1 containing sodium cocoyl isethionate (SCI) and / or sodium lauroyl sarcosinate (SLS), the anionic surfactant is added to the mixing vessel and mixed until completely dissolved (no visible particles remain and the batch is clear). After the SCI and / or SLS are completely dissolved, the following materials may be added to the mixing vessel: sodium benzoate, tetrasodium EDTA, sodium salicylate, alkylamidopropyl betaine, and rhamnolipids. Mix the contents of the vessel for at least 10 minutes, then cool to below 35°C. Prepare a polyquaternium-10 slurry with water and immediately add it to the mixing vessel and mix for 10 minutes. Fragrances may be added to the mixture and mixed for at least 2 minutes. Titrate the mixture with sodium hydroxide until the desired pH is reached. Add deionized water to bring the final volume to 100%. Mix the mixture for at least 10 minutes until homogeneity is achieved.

[0068] For the remaining compositions (i.e., C3-C5 and Inv 2-Inv 6), add deionized water to the mixing vessel and heat to 75°C ± 3°C while stirring. Next, add the following materials to the mixing vessel: sodium benzoate, tetrasodium EDTA, sodium salicylate, alkylamidopropyl betaine, and rhamnolipid. Mix the contents of the vessel for at least 10 minutes. Next, cool the batch to below 35°C. Prepare a polyquaternium-10 slurry with water and immediately add it to the mixing vessel and mix for 10 minutes. Next, add the fragrance to the mixture and mix for at least 2 minutes. Titrate the mixture with sodium hydroxide until the desired pH is reached. Add deionized water to bring the final volume to 100%. Mix the mixture for at least 10 minutes until homogeneity is achieved.

[0069] [Table 1] 1 Rhamnolipids (approximately 50% active) from Evonik's Rheance® One brand. 2 Rhamnolipids (approximately 38% active) of the Bio-RL1 (trademark) brand manufactured by Wanhua Carfil. 3 Rhamnolipids (approximately 50% active) of the REnuva® RL-50 brand manufactured by BioReNuva. 4 Manufactured by GlycoSurf, Utah (~100% active) * Significant difference compared to the comparative example using conventional rhamnolipid surfactants.

[0070] As shown in Table 1, the compositions of the present invention performed better than the comparative compositions at both low surfactant levels (0.6%) and high surfactant levels (8.5%). Surprisingly, compared to conventional rhamnolipid surfactants and Rha-C 10 and Rha-C 12 Inv 4, which contained the blend, performed better than the comparative examples and some of the other examples of the present invention.

[0071] Table 2 below provides predictive examples of compositions of the present invention, including other sulfate-free surfactants. The compositions in Table 2 can be prepared using the conventional processes described above.

[0072] [Table 2]

[0073] [Table 3]

[0074] [Table 4]

[0075] [Table 5] 1 RHEANCE ONE brand glycolipid surfactant (approximately 50% active). 2 Rha-C10 (approximately 100% active) manufactured by GlycoSurf, Utah. 3 Rha-C11 (approximately 100% active) manufactured by GlycoSurf, Utah. 4 Rha-C12 (approximately 100% active) manufactured by GlycoSurf, Utah.

[0076] Example 3: Foaming synergistic effect This example is Rha-C 10 Surfactants, Rha-C 12 This study demonstrates the unexpected foam volume synergistic effect exhibited by shampoos containing a mixture of surfactants and conventional rhamnolipid surfactants. 10 and Rha-C 12 Surfactants are generally undesirable for use in conventional shampoos, and therefore tend to be treated as more expensive specialty ingredients than conventional glycolipid surfactants. 10 and Rha-C 12 By mixing surfactants with conventional glycolipid surfactants, it may be possible to reduce the manufacturing cost of shampoo and provide superior foam volume.

[0077] This example demonstrates various levels of Rha-C 10 , Rha-C 12 Three legs (A-C) of compositions containing a conventional glycolipid surfactant (RHEANCE ONE, manufactured by Evonik) were tested. The test compositions were simple solutions of water and the surfactant. The foaming volume was measured according to the foaming volume method described above. The foaming volumes recorded for each data point are summarized in Table 3 and shown in the figure.

[0078] [Table 6]

[0079] As can be seen from Table 3 and the figure, Rha-C in composition A 10 , Rha-C 12 The combination of conventional glycolipid surfactants, and compositions A, provided unexpectedly better foam volume than compositions B and C. In particular, the provided composition A was Rha-C 10 vs Rha-C 12 The ratio is 1:1, and Rha-C 10 +Rha-C 12 vs. conventional rhamnolipids or Rha-C 12 When the ratio of each component was between 1:3 and 1:0, it seemed to provide unexpectedly good foam volume.

[0080] Examples / Combinations 1. Rha-C 10 , Rha-C 11 , Rha-C 12 , Rha-C 13 , and rhamnolipid surfactants selected from combinations thereof, A surfactant system comprising an anionic surfactant, an amphoteric surfactant, a bipolar surfactant, a nonionic surfactant, a cationic surfactant, and additional surfactants selected from combinations thereof, which are sulfate-free. 2. Rha-C 10 Surfactants and Rha-C 12 A surfactant system as described in paragraph 1, comprising a surfactant. 3. Rha-C 10 Surfactants and Rha-C 12 The surfactant is Rha-C in a ratio of 1:10 to 10:1, preferably 1:5 to 5:1, more preferably 1:2 to 2:1, and most preferably 1:1. 12 The surfactant system described in paragraph 2, present in a weight ratio of Rha-C10 to [the specified component]. 4. Rha-C 10 Surfactants and Rha-C 12 The surfactant system according to paragraph 2 or 3, wherein the surfactant constitutes 1% to 80% by weight, preferably 3% to 50% by weight, of the total surfactants in the personal care composition. A surfactant system according to any one of paragraphs 1 to 4, further comprising less than 5.3% of di-rhamnolipid surfactants and mono-rhamno-di-lipid surfactants. 6. a) Surfactant system 25% to 75% by weight, Rha-C 10 , Rha-C 11 , Rha-C 12 , Rha-C 13 , and rhamnolipid surfactants selected from combinations thereof, b) A surfactant system according to any one of paragraphs 1 to 5, comprising 25% to 75% by weight of a di-rhamno-di-lipid surfactant, wherein the surfactant in i) and the surfactant in ii) are di-rhamno-di-lipid surfactants that exhibit a synergistic foaming volume by foam discharge method. 7. The surfactant system according to paragraph 6, wherein the rhamnolipid surfactant in i) and the di-rhamno-di-lipid surfactant in ii) provide a synergistic foam volume by the blender foam volume method. 8. The additional surfactant is selected from cocoamphoacetate, cocoamphodiaacetate, lauroamphoacetate, lauroamphodiaacetate, amidebetaine, amidesulfobetaine, hydroxysultaine, isethionate, sarcosinate, sulfonate, taurate, alaninate, glycinate, glutamate, sulfosuccinate, and mixtures thereof, according to any of paragraphs 1 to 7. 9. a) A surfactant system described in any of paragraphs 1 to 8, b) A personal care composition comprising a dermatologically acceptable carrier. 10. The composition according to paragraph 9, wherein the composition exhibits a foaming height of at least 140 according to the oil foaming height method. 11. The composition according to paragraph 9 or 10, wherein the composition exhibits a foaming height of at least 55 by the dirt foaming height method. The composition according to paragraph 9 or 10, further comprising less than 12.1% inorganic salts. 13. The composition according to any one of paragraphs 9 to 12, further comprising a dispersed gel reticular structure. 14. The composition according to paragraph 13, wherein the gel network comprises an aliphatic alcohol, a gel network surfactant, and a liquid carrier, the aliphatic alcohol being in the form of liquid crystal droplets. 15. The dispersed gel network structure is a composition according to paragraph 13 or 14, comprising 0.05% by weight or more of an aliphatic alcohol and 0.01% by weight or more of a gel network structure surfactant selected from anionic surfactants, cationic surfactants, bipolar surfactants, nonionic surfactants, and mixtures thereof. 16. The composition according to any one of paragraphs 9 to 15, further comprising a cationic polymer. 17. A method for cleaning the surface of a target object, Wetting the surface of the target object with water, Apply 1 to 50 g of the personal care composition described in any one of paragraphs 9 to 16 to a wet body surface, The composition is applied to a wet body surface to generate foam, A method comprising rinsing the composition off the surface of a target object with water. 18. Surfactant-based surfactants include Rha-C 10 Surfactants and Rha-C 12 The method according to paragraph 17, comprising a surfactant. 19. Rha-C 10 Surfactants and Rha-C 12 The surfactant is Rha-C in a ratio of 5:1 to 1:5, preferably 2:1 to 1:2, more preferably 1:1. 12 Rha-C for 10 The method described in paragraph 18, which exists in the weight ratio of the following. 20. Rha-C 10 Surfactants and Rha-C 12 The method according to paragraph 18 or 19, wherein the surfactant constitutes 1% to 80% by weight, preferably 3% to 50% by weight, of the total surfactants in the personal care composition. 21. The method according to any one of paragraphs 17 to 20, wherein the rhamnolipid surfactant(s) have 4 to 15 HLBs.

[0081] The dimensions and values ​​disclosed herein should not be understood as being strictly limited to the exact numerical values ​​listed. Instead, unless otherwise indicated, each such dimension is intended to mean both the listed value and the functionally equivalent range encompassing that value. For example, a dimension disclosed as "40 mm" is intended to mean "approximately 40 mm."

[0082] All documents cited herein, including cross-referenced or related patents or applications, are incorporated herein in their entirety by reference unless expressly excluded or otherwise limited. No citation of any document shall be deemed prior art to any invention disclosed or claimed herein, nor shall it be deemed to teach, suggest or disclose any such invention, either alone or in combination with any other reference(s). Furthermore, in the event of any conflict between the meaning or definition of any term in this document and the meaning or definition of the same term in any document incorporated by reference, the meaning or definition given to the term in this document shall prevail.

[0083] While specific embodiments of the present invention have been illustrated and described, it will be apparent to those skilled in the art that various other changes and modifications can be made without departing from the spirit and scope of the invention. Therefore, it is intended that all such changes and modifications within the scope of the invention be covered in the appended claims.

Claims

1. Rha-C １０ , Rha-C １１ , Rha-C １２ , Rha-C １３ , and rhamnolipid surfactants selected from combinations thereof, A surfactant system comprising an anionic surfactant, an amphoteric surfactant, a bipolar surfactant, a nonionic surfactant, a cationic surfactant, and additional surfactants selected from combinations thereof, which are sulfate-free.

2. Rha-C １０ Surfactants and Rha-C １２ A surfactant system according to claim 1, comprising a surfactant.

3. the aforementioned Rh a-C １０ surfactant and the aforementioned Rh a-C １２ The surfactant is present at a weight ratio of Rh a-C 10 to Rh a-C of 1:10 to 10:

1. The surfactant system according to claim 2 １２ ​

4. The Rha-C １０ Surfactants and Rha-C １２ The surfactant system according to claim 2, wherein the surfactant constitutes 1% to 80% by weight of the total surfactant in the surfactant system.

5. The surfactant system according to claim 1, further comprising less than 3% of a di-rhamnolipid surfactant and a mono-rhamnodi-lipid surfactant.

6. The surfactant system according to claim 1, wherein the additional surfactant is selected from cocoamphoacetate, cocoamphodiaacetate, lauroamphoacetate, lauroamphodiaacetate, amidebetaine, amidesulfobetaine, hydroxysultaine, isethionate, sarcosinate, sulfonate, taurate, alaninate, glycinate, glutamate, sulfosuccinate, and mixtures thereof.

7. The surfactant system described in claim 1, A dermatologically acceptable carrier, A personal care composition containing the following:

8. The composition according to claim 7, further comprising a dispersed gel network structure.

9. The composition according to claim 8, wherein the gel network structure comprises an aliphatic alcohol, a gel network structure surfactant, and a liquid carrier, and the aliphatic alcohol is in the form of liquid crystal droplets.

10. The composition according to claim 8, wherein the dispersed gel network structure comprises 0.05% by weight or more of an aliphatic alcohol and 0.01% by weight or more of a gel network structure surfactant selected from anionic surfactants, cationic surfactants, bipolar surfactants, nonionic surfactants, and mixtures thereof.

11. The composition according to claim 7, further comprising a cationic polymer.

12. The composition according to claim 7, further comprising less than 1% inorganic salt.

13. The composition according to claim 7, wherein the composition exhibits a foaming height of at least 50 by the oil foaming height method.

14. The surfactant system according to claim 7, wherein the composition exhibits a foaming height of at least 150 according to the dirt foaming height method.

15. A method for cleaning the surface of a target object, The surface of the target object is wetted with water, Apply 1 to 50 g of the personal care composition according to claim 7 to the wet body surface, The composition is applied to the wet body surface to generate foam, Rinsing the composition from the surface of the target object with water, Methods that include...

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