Synergistic pesticide mixture, its use, method, and seeds

Abstract

The present invention relates to a compound of formula (I) 1 , R 2 , R 3 , R 4 , R 5 , and R 6 is as defined herein], its oxide or salt, and at least one insecticidally active compound (II) or at least one fungicidally active compound (III). [Formula 1] TIFF2023533007000030.tif5653

Description

[Technical Field]

[0001] The present invention relates to a pesticide mixture comprising at least one pesticide thietanyloxy compound of formula (I), an oxide thereof, or a salt thereof as component (1), and at least one insecticide compound (II) or at least one fungicide compound (III) as component (2). Furthermore, the present invention relates to a method for controlling plant invertebrate pests and / or plant pathogenic fungi, the use of the mixture for seed treatment, a method for protecting seeds, and corresponding treated seeds. [Background technology]

[0002] One of the challenges / necessities in pest control is to reduce the application rate of pesticides in order to achieve effective pest control while simultaneously reducing or avoiding environmental or toxicological impacts. The need for pest control agents that are effective against a wide range of pests is another challenge.

[0003] There is also a need for pest control agents that provide rapid action and long-lasting activity in order to reduce the number of applications.

[0004] Another problem associated with the use of a single biological agent is that, in most cases, repeated and exclusive application leads to the development of natural or adaptive resistance to the biologically active compound. Therefore, there is a need for pest control measures that help prevent or overcome resistance.

[0005] Furthermore, there is a demand for pest-killing mixtures that, when applied, improve plant health, increase plant reproductive vitality, or enhance yield.

[0006] Therefore, in addition to addressing one or more of the problems discussed above, it is highly desirable to obtain a pesticidal active mixture that demonstrates a higher control effect while reducing environmental or toxicological impacts.

[0007] WO2019150220 discloses compounds of the following formula.

[0008] [Chemical formula] [In the formula, W 1 and W 2 represent O, B 1 and B 2 represent C, D is fragment D4

[0009] [Chemical formula] (where x is hydrogen, fluorine or chlorine) and Z 1 represents O, E represents a thietanyl group, R 1 is NR 10 R 11 in the formula, R 10 is hydrogen or methyl, R 3 represents cyano, fluorine, chlorine, bromine, methyl and trifluoromethyl, R 4 represents hydrogen, R 5 represents hydrogen, halogen, R 11 represents C1-C6 alkyl, C3-C8 cycloalkyl, and C4-C8 cycloalkyl-C1-C6 alkyl, m represents the integer 2] [Summary of the Invention]

[0010] Surprisingly, the biotoxic mixture according to the present invention has been found to not only provide an additive enhancement of the range of action with respect to the pests / plant pathogens to be controlled (which was expected in principle), but also to achieve a synergistic effect. At such low application rates, even if the individual effects of these two compounds become reduced or disappear, the synergistic effect of the biotoxic mixture of the present invention helps maintain the level of effectiveness, and the application rates of component (1), selected from the thietanyloxy compounds of formula (I), and component (2), which is at least one additional insecticidal compound (II) or at least one fungicidal compound (III), are reduced. This synergistic effect also makes it possible to substantially broaden the range of plant pathogens that can be controlled, while simultaneously increasing safety during use.

[0011] Therefore, the present invention provides a constituent component (1) of formula (I)

[0012] [ka] [In the formula, R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 This is as defined in the specification. We provide a mixture of thietanyloxy compounds, their oxides, or salts that are biotoxic and contain pesticide activity. Component (2) is, (II-1) Acetylcholinesterase (AChE) inhibitors, (II-2) GABAergic chloride ion channel blockers, (II-3) Sodium channel modulator, (II-4) Nicotinic acetylcholine receptor (nAChR) competitive modulators, (II-5) Nicotinic acetylcholine receptor (nAChR) allosteric modulator - site I, (II-6) Glutamate-gated chloride ion channel (GluCl) allosteric modulator (II-7) Juvenile hormone mimetic, (II-8) Other nonspecific (multisite) inhibitors, (II-9) String organ TRPV channel modulator, (II-10) Mite growth inhibitors that act on CHS1, (II-11) Microbial-derived insect midgut endometrium disruptor, (II-12) Mitochondrial ATP synthase inhibitors, (II-13) Oxidative phosphorylation uncoupling agents via disruption of the proton gradient, (II-14) Nicotinic acetylcholine receptor (nAChR) channel blockers, (II-15) Chitin biosynthesis inhibitors that act on CHS1, (II-16) Chitin biosynthesis inhibitor type 1, (II-17) Molting inhibitors, (II-18) Ecdysone receptor agonist, (II-19) Octopamine receptor agonist, (II-20) Mitochondrial electron transport chain complex III inhibitors, (II-21) Mitochondrial electron transport chain complex I inhibitors, (II-22) Voltage-dependent sodium channel blockers, (II-23) Acetyl-CoA carboxylase inhibitors, (II-24) Mitochondrial electron transport chain complex IV inhibitors, (II-25) Mitochondrial electron transport chain complex II inhibitors, (II-26) ryanodine receptor modulator, (II-27) Chord organ modulator - Target site unspecified, (II-28) GABAergic chloride ion channel allosteric modulator, (II-29) Baculovirus, (II-30) Nicotinic acetylcholine receptor (nAChR) allosteric modulator - site II, (II-31) Insecticidal compounds with unknown or unclear mechanisms of action, (II-32) Biological pesticides, and (II-33) Biochemical pesticides having insecticidal, acaricidal, molluscicidal, pheromone, and / or nematicidal activity It is at least one insecticidal compound (II) selected from the group consisting of the following.

[0013] Another aspect of the present invention provides a pesticide-causing biological mixture comprising a thiethanyloxy compound of formula (I), its oxide or salt, as component (1), and component (2) is (A) Ergosterol synthesis inhibitors, (B) Respiratory chain complex I or II inhibitors, (C) Respiratory chain complex III inhibitors, (D) Mitotic and cell division inhibitors, (E) Compounds capable of multi-site activity, (F) Compounds capable of inducing host defense, (G) Amino acid and / or protein biosynthesis inhibitors, (H)ATP production inhibitors, (I) Cell wall synthesis inhibitors, (J) Lipid and membrane synthesis inhibitors, (K) Melanin biosynthesis inhibitor, (L) Nucleic acid synthesis inhibitors, (M) Signal transduction inhibitors, (N) Compounds that can act as uncoupling agents, (O) Other disinfectants, (P)HDAC inhibitors, and (Q) Compounds that can act as toxicity mitigaters It is at least one fungicidal compound (III) selected from the group consisting of the following.

[0014] In yet another embodiment, the present invention provides a method for controlling plant invertebrate pests and / or plant pathogenic fungi, comprising the step of applying a pesticide mixture to the pests and / or microorganisms and / or plants, plant parts, seeds, fruits and their habitats or soil. [Modes for carrying out the invention]

[0015] Definition: In defining the symbols assigned to the above formula, the following general terms were used to represent substituents:

[0016] The term "hydrogen" also includes isotopes of hydrogen, preferably deuterium and tritium, more preferably deuterium.

[0017] The term "halogen" (in combination with, for example, haloalkyl, haloalkoxy, etc.) includes fluorine, chlorine, bromine, and iodine, preferably fluorine, chlorine, and bromine.

[0018] The term "alkyl" (including combinations with alkylthio, alkoxy, etc.) refers to saturated, linear or branched hydrocarbyl groups having 1 to 6 carbon atoms, such as C1-C6 alkyl groups, such as methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1,1-dimethylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, and 1,1-dimethylpropyl. This includes 1,2-dimethylpropyl, 1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4-methylpentyl, 1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl, 2-ethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl, l-ethyl-1-methylpropyl, 1-ethyl-2-methylpropyl, heptyl, and octyl. When the alkyl is at the end of a complex substituent, for example in a cycloalkyl-alkyl, some of the initial complex substituents, e.g., alkyl, may be monosubstituted or polysubstituted with cycloalkyls, either equally or differently, and independently.

[0019] The term "cycloalkyl" refers to alkyl groups that form a closed ring. Non-limiting examples include, but are not limited to, cyclopropyl, cyclopentyl, and cyclohexyl. This definition also applies to cycloalkyl groups as part of a complex substituent, such as cycloalkyl-alkyl, unless otherwise specifically defined.

[0020] Depending on the properties of the substituents, the compounds of formula (I) or their combined partners that form part of the biotoxic mixture of the present invention may exist as mixtures of different possible isomers, particularly stereoisomers, e.g., E and Z, threo and erythro, as well as optical isomers, and, where appropriate, as mixtures of tautomers. Where applicable, the compounds of formula (I) or their combined partners that form part of the biotoxic mixture of the present invention may include both E and Z isomers, as well as threo and erythro, and optical isomers, any mixtures of these isomers, and possible tautomers.

[0021] Any of the compounds of formula (I) or their combination partners that form part of the biocidal mixture may exist in one or more optical, geometric, or chiral isomeric forms, depending on the number of asymmetric centers in the compound. The compounds of formula (I) or their combination partners that form part of the biocidal mixture include all optical isomers and their racemic or scalemic mixtures (the term "scalemic" refers to a mixture of enantiomers in different proportions), as well as mixtures of all possible stereoisomers, in all proportions. Diastereomers and / or optical isomers can themselves be separated according to methods known to those skilled in the art.

[0022] Any of the compounds of formula (I) or their combination partners that form part of the biotoxic mixture may also exist in one or more geometric isomeric forms, depending on the number of double bonds in the compound. The compounds of formula (I) or their combination partners that form part of the biotoxic mixture include all geometric isomers and all possible mixtures in all proportions. Geometric isomers can be separated according to general methods, and these methods are known to those skilled in the art.

[0023] Depending on the properties of the substituents, the compounds of formula (I) may also exist in one or more geometric isomeric forms depending on the relative positions of the substituents on ring B (syn / anti or cis / trans). Thus, the present invention relates to all syn / anti (or cis / trans) isomers and all possible syn / anti (or cis / trans) mixtures in all proportions. Syn / anti (or cis / trans) isomers can be separated according to general methods, and these methods are known to those skilled in the art.

[0024] The compound of formula (I) can be reacted with an acid to obtain a salt.

[0025] Examples of inorganic acids include hydrohalic acids, such as hydrogen fluoride, hydrogen chloride, hydrobromic acid, and hydrogen iodide, sulfuric acid, phosphoric acid, and nitric acid, as well as acidic salts, such as NaHSO4 and KHSO4.

[0026] Suitable organic acids include, for example, formic acid, carbonates and alkanes, such as acetic acid, trifluoroacetic acid, trichloroacetic acid and propionic acid, as well as glycolic acid, thiocyanic acid, lactic acid, succinic acid, citric acid, benzoic acid, cinnamic acid, oxalic acid, alkylsulfonic acids (sulfonic acids having a linear or branched alkyl group having 1 to 20 carbon atoms), arylsulfonic acids or disulfonic acids (having aromatic groups, e.g., phenyl and naphthyl, one or two sulfonic acid groups), alkylphosphonic acids (phosphonic acids having a linear or branched alkyl group having 1 to 20 carbon atoms), arylphosphonic acids or diphosphonic acids (having aromatic groups, e.g., phenyl and naphthyl, one or two phosphonic acid groups), and these alkyl and aryl groups may have further substituents, such as p-toluenesulfonic acid, salicylic acid, p-aminosalicylic acid, 2-phenoxybenzoic acid, 2-acetoxybenzoic acid, etc.

[0027] Taking the above into consideration, the present invention provides a constituent component (1) of formula (I)

[0028] [ka] [In the formula, R 1 This is selected from the group consisting of C1-C6 alkyl, C3-C5 cycloalkyl, C3-C5 cycloalkyl-C1-C6 alkyl, and C1-C6 alkyl-C3-C5 cycloalkyl. R 2 It is selected from the group consisting of hydrogen and methyl, R 3 It is selected from the group consisting of halogens and cyanos, R 4 It is selected from the group consisting of methyl, fluorine, chlorine, bromine, and trifluoromethyl, R 5 It is selected from the group consisting of hydrogen, fluorine, and chlorine. R 6 [Selected from the group consisting of hydrogen, methyl, and trifluoromethyl] At least one pesticide containing a thietanyloxy compound or its agriculturally acceptable salt, isomer / structural isomer, stereoisomer, diastereomer, enantiomer, tautomer, metal complex, polymorph or N-oxide, Component (2): at least one insecticidal compound (II) and / or at least one fungicidal compound (III) A biological mixture containing a mixture of the following, At least one insecticidal compound (II) (II-1) Acetylcholinesterase (AChE) inhibitors, (II-2) GABAergic chloride ion channel blockers, (II-3) Sodium channel modulator, (II-4) Nicotinic acetylcholine receptor (nAChR) competitive modulators, (II-5) Nicotinic acetylcholine receptor (nAChR) allosteric modulator - site I, (II-6) Glutamate-gated chloride ion channel (GluCl) allosteric modulator (II-7) Juvenile hormone mimetic, (II-8) Other nonspecific (multisite) inhibitors, (II-9) String organ TRPV channel modulator, (II-10) Mite growth inhibitors that act on CHS1, (II-11) Microbial-derived insect midgut endometrium disruptor, (II-12) Mitochondrial ATP synthase inhibitors, (II-13) Oxidative phosphorylation uncoupling agents via disruption of the proton gradient, (II-14) Nicotinic acetylcholine receptor (nAChR) channel blockers, (II-15) Chitin biosynthesis inhibitors that act on CHS1, (II-16) Chitin biosynthesis inhibitor, type 1, (II-17) Molting inhibitors, (II-18) Ecdysone receptor agonist, (II-19) Octopamine receptor agonist, (II-20) Mitochondrial electron transport chain complex III inhibitors, (II-21) Mitochondrial electron transport chain complex I inhibitors, (II-22) Voltage-dependent sodium channel blockers, (II-23) Acetyl-CoA carboxylase inhibitors, (II-24) Mitochondrial electron transport chain complex IV inhibitors, (II-25) Mitochondrial electron transport chain complex II inhibitors, (II-26) ryanodine receptor modulator, (II-27) Chord organ modulator - Target site unspecified, (II-28) GABAergic chloride ion channel allosteric modulator, (II-29) Baculovirus, (II-30) Nicotinic acetylcholine receptor (nAChR) allosteric modulator - site II, (II-31) Insecticidal compounds with unknown or unclear mechanisms of action, (II-32) Biological pesticides, and (II-33) Biochemical pesticides having insecticidal, acaricidal, molluscicidal, pheromone, and / or nematicidal activity, Selected from the group consisting of, At least one fungicidal compound (III) (A) Ergosterol synthesis inhibitors, (B) Respiratory chain complex I or II inhibitors, (C) Respiratory chain complex III inhibitors, (D) Mitotic and cell division inhibitors, (E) Compounds capable of multi-site activity, (F) Compounds capable of inducing host defense, (G) Amino acid and / or protein biosynthesis inhibitors, (H)ATP production inhibitors, (I) Cell wall synthesis inhibitors, (J) Lipid and membrane synthesis inhibitors, (K) Melanin biosynthesis inhibitor, (L) Nucleic acid synthesis inhibitors, (M) Signal transduction inhibitors, (N) Compounds that can act as uncoupling agents, (O) Other disinfectants, (P)HDAC inhibitors, and (Q) Compounds that can act as toxicity mitigaters Selected from the group consisting of, We provide a biological mixture that kills pests.

[0029] In one embodiment, the present invention provides a constituent component (1) of formula (I)

[0030] [ka] [In the formula, R 1This is selected from the group consisting of C1-C6 alkyl, C3-C5 cycloalkyl, C3-C5 cycloalkyl-C1-C6 alkyl, and C1-C6 alkyl-C3-C5 cycloalkyl. R 2 It is selected from the group consisting of hydrogen and methyl, R 3 It is selected from the group consisting of halogens and cyanos, R 4 It is selected from the group consisting of methyl, fluorine, chlorine, bromine, and trifluoromethyl, R 5 It is selected from the group consisting of hydrogen, fluorine, and chlorine. R 6 [Selected from the group consisting of hydrogen, methyl, and trifluoromethyl] We provide a mixture of thietanyloxy compounds or agriculturally acceptable salts thereof, isomers / structural isomers, stereoisomers, diastereomers, enantiomers, tautomers, metal complexes, polymorphs, or N-oxides that are biotoxic. Component (2) is, (II-1) Acetylcholinesterase (AChE) inhibitors: Select from the following classes, (II-1A) Carbamates: Alanicarb (Z001), Aldicarb (Z002), Bendiocarb (Z003), Benfuracarb (Z004), Butoxycarboxyle (Z005), Butoxycarboxyle (Z006), Carbaryl (Z007), Carbofuran (Z008), Carbosulfan (Z009), Ethiophenecarb (Z010), Phenobucarb (Z011), Formetanate (Z012), Fura This includes thiocarb (Z013), isoprocarb (Z014), methiocarb (Z015), methomyl (Z016), metholcarb (Z017), oxamyl (Z018), pyrimicarb (Z019), propoxul (Z020), thiodicarb (Z021), thiophanox (Z022), triazamate (Z023), trimetacarb (Z024), XMC (Z025), and xylylcarb (Z026), or (II-1B) Organophosphorus compounds: Acephate (Z027), Azamethiphos (Z028), Adinphos-ethyl (Z029), Adinphos-methyl (Z030), Kazsaphos (Z031), Chloretoxyphos (Z032), Chlorfenbinphos (Z033), Chlormephos (Z034), Chlorpyrifos (Z035), Chlorpyrifos-methyl (Z036), Coumaphos (Z037), Cyanophos (Z038), Demeton-s-methyl (Z039), Diazinon (Z040), Dichlorvos / ddvp (Z041), Di Clotophos (Z042), Dimethoate (Z043), Dimethylvinphos (Z044), Disulfon (Z045), EPN (Z046), Ethion (Z047), Etoprophos (Z048), Fanfar (Z049), Phenamiphos (Z050), Fenitrothion (Z051), Fenthion (Z052), Fosthiazate (Z053), Heptenophos (Z054), Imisiaphos (Z055), Isofenphos (Z056), Isopropyl o-(methoxyaminothio-phosphoryl) salicylate (Z057 ), isoxathion (Z058), malathion (Z059), mecarbam (Z060), methamidophos (Z061), methidathion (Z062), mevinphos (Z063), monoclotophos (Z064), naled (Z065), omethoate (Z066), oxydemeton-methyl (Z067), parathion (Z068), parathion-methyl (Z069), fenthoate (Z070), folate (Z071), fosalon (Z072), fosmet (Z073), phosphamidone (Z074), fox Includes sym (Z075), pyrimiphos-methyl (Z076), profenofos (Z077), propethamfos (Z078), prothiofos (Z079), pyraclofos (Z080), pyridaphenthion (Z081), quinalfos (Z082), sulfotep (Z083), tebupyrimfos (Z084), temefos (Z085), terbufos (Z086), tetrachlorvinfos (Z087), thiometone (Z088), triazofos (Z089), trichlorfon (Z090), and bamidothion (Z091); (II-2) GABAergic chloride ion channel blockers: Select from the following classes, (II-2A) Cyclic diene organochlorine systems: containing chlordane (Z092) and endosulfan (Z093); or (II-2B) Phenylpyrazole derivatives (fiproles): including ethiprole (Z094), fipronil (Z095), flufiprole (Z096), pyrafluprole (Z097), and pyriprole (Z0918); (II-3) Sodium channel modulator: Select from the following classes, (II-3A) Pyrethroids / Pyrethrins: Acrinatrin (Z099), Allethrin (Z100), d-cis-trans Allethrin (Z101), d-trans-Allethrin (Z102), Bifenthrin (Z103), Biorethrin (Z104), Biorethrin-cyclopentenyl isomer (Z105), Violethmetrin (Z106), Cycloprotrin (Z107), Cyfluthrin (Z108), Beta-Cyfluthrin (Z109), Siha Rotrin (Z110), lambda-cyhalotrin (Z111), gamma-cyhalotrin (Z112), cypermethrin (Z113), alpha-cypermethrin (Z114), beta-cypermethrin (Z115), theta-cypermethrin (Z116), zeta-cypermethrin (Z117), cyphenothrin [(1r)-trans-isomer] (Z118), deltamethrin (Z119), empenthrin [(ez)-(1r)-isomer] (Z120), esphenothrin Imbalerate (Z121), etofenprox (Z122), fenpropathrin (Z123), fenvalerate (Z124), flucitrinate (Z125), flumethrin (Z126), tau-fluvalinate (Z127), halfenprox (Z128), imiprothrin (Z129), meperfluthrin (Z130), metofluthrin (Z131), monfluorothrin (Z132), cadetrin (Z133), permethrin (Z134), f This includes enenotrin [(1r)-trans-isomer] (Z134), palethrin (Z135), profluthrin (Z136), pyrethrin (pyretram) (Z137), resmethrin (Z138), silafluofen (Z139), tefluthrin (Z140), tetramethylfluthrin (Z141), tetramethrin (Z142), tetramethrin [(1r)-isomer] (Z143), tralomethrin (Z144), and transfluthrin (Z145); or (II-3B) DDT (Z146) or Methoxychlor (Z147) (II-4) Nicotinic acetylcholine receptor (nAChR) competitive modulators: Select from the following classes, (II-4A) Neonicotinoids: Acetamiprid (Z148), Clothianidin (Z149), Dinotefuran (Z150), Imidaclopride (Z151), Nitenpyram (Z152), Thiaclopride (Z153), Thiamethoxam (Z154), 1-[(6-chloro-3-pyridinyl)methyl]-2,3,5,6,7,8-hexahydro-9-nitro-(5S,8R)-5,8- Includes poxy-H-imidazo[1,2-a]azepine (Z155); 1-[(6-chloro-3-pyridyl)methyl]-2-nitro-1-[(E)-pentylideneamino]guanidine (Z156); and 1-[(6-chloro-3-pyridyl)methyl]-7-methyl-8-nitro-5-propoxy-3,5,6,7-tetrahydro-2H-imidazo[1,2-a]pyridine (Z157); or (II-4B) Nicotine (Z158); or (II-4C) Sulfoximine series: containing sulfoxaflor (Z159); or (II-4D) Butenolide series: Flupyradiflon: (Z160) or (II-4E) Mesoionic system: containing triflumesopyrime (Z161) and dichloromethothiaz (Z162), (II-4F) Flupyrimine (Z163), (II-5) Nicotinic acetylcholine receptor (nAChR) allosteric modulators - Site I: Selected from the spinosin system class: including spinetram (Z164) and spinosad (Z165), (II-6) Glutamate-gated chloride ion channel (GluCl) allosteric modulators: Selected from the avermectin / milbemycin class: Including abamectin (Z166), emamectin benzoate (Z167), lepimectin (Z168), and milbemectin (Z169), (II-7) Juvenile hormone mimetic: Select from the following classes, (II-7A) Juvenile hormone analogs: including hydroprene (Z170), quinoprene (Z171), and methoprene (Z172); or (II-7B) Phenoxybcarb (Z173); or (II-7C) Pyriproxyfen (Z174), (II-8) Other nonspecific (multisite) inhibitors: Select from the following classes: (II-8A) Alkyl halides: including methyl bromide (Z175) and other alkyl halides (Z176); or (II-8B) Chloropicrin (Z177); or (II-8C) Fluoride system: containing cryolite (aluminum sodium fluoride) (Z178) and sulfuryl fluoride (Z179); or (II-8D) Borates: comprising borax (Z180), boric acid (Z181), disodium octaborate (Z182), sodium borate (Z183), and sodium metaborate (Z184); or (II-8E) Tartarite (Z185); or (II-8F) Methyl isothiocyanate generator: containing dazomet (Z186) and metam (Z187), (II-9) String organ TRPV channel modulator: Select from the following classes, (II-9A) Pyridineazomethine derivatives: including pymetrozine (Z188) and pyrifluquinazone (Z189); or (II-9B) Pylopen series: including Afidopilopen (Z190), (II-10) Mite growth inhibitors acting on CHS1: Select from the following classes, (II-10A) Clofentezine (Z191), Hexythiazox (Z192), and Diflovidazine (Z193); or (II-10B) Ethoxazole (Z194) (II-11) Microbial-derived insect midgut endometrial disruptors: Select from the following classes, (II-11A) Bacillus thuringiensis (Z195) and the insecticidal proteins they produce: bacillus thuringiensis or bacillus sphaericus and the insecticidal proteins they produce, for example, bacillus thuringiensis subsp. Israelensis, bacillus thuringiensis subsp. Aizawai, bacillus thuringiensis subsp. kurstaki and bacillus thuringiensis subsp. Tenebrionis, or Bt crop proteins: including Cry1Ab, Cry1Ac, Cry1Fa, Cry1A.105, Cry2Ab, Vip3A, mCry3A, Cry3Ab, Cry3Bb and Cry34 / 35Ab1, (II-12) Mitochondrial ATP synthase inhibitors: Select from the following classes, (II-12A) Diafenthiurone (Z197); or (II-12B) Organotin acaricides: containing azocyclotin (Z198), cyhexatin (Z199), and fenbutatin oxide (Z200), or (II-12C) Propalgit (Z201), or (II-12D) Tetradiphon (Z202), (II-13) Oxidative phosphorylation uncoupling agents via disruption of the proton gradient: Select from the following classes, (II-13A) Pyrrole series: including chlorfenapyr (Z203); or (II-13B) Dinitrophenol series: containing DNOC(Z204); or (II-13C) Sulfuramide (Z205) (II-14) Nicotinic acetylcholine receptor (nAChR) channel blockers: Selected from the class of nereistoxin analogs: including bensultap (Z206), cartap hydrochloride (Z207), thiocyclam (Z208), and thiosultap sodium salt (Z209), (II-15) Chitin biosynthesis inhibitors acting on CHS1: Selected from the class of benzoylureas: including bistriflurone (Z210), chlorfluazurone (Z211), diflubenzuron (Z212), flucycloxurone (Z213), flufenoxurone (Z214), hexaflumurone (Z215), lufenuron (Z216), novaron (Z217), nobiflumuron (Z218), teflubenzuron (Z219), and triflumuron (Z220). (II-16) Chitin biosynthesis inhibitor type 1: Buprofezin (Z221) (II-17) Molting inhibitors, Diptera insects: containing silamazin (Z222), (II-18) Ecdysone receptor agonists: Selected from the diacylhydrazine class: including methoxyfenozide (Z223), tebufenozide (Z224), halofenozide (Z225), fenozide (Z226), and chromafenozide (Z227); (II-19) Octopamine receptor agonists: including amitraz (Z228), (II-20) Mitochondrial electron transport chain complex III inhibitors: Select from the following classes, (II-20A) Hydramethylnon (Z229); or (II-20B) Asekinosyl (Z230); or (II-20C) Full acrylate (Z231); or (II-20D) Bifenazate (Z232), (II-21) Mitochondrial electron transport chain complex I inhibitors: Select from the following classes, (II-21A) METI acaricides and insecticides: including phenazaquin (Z233), fenpyroximate (Z234), pyrimidifen (Z235), pyridaben (Z236), tebufenpyrad (Z237), and tolfenpyrad (Z238); or (II-21B) Rotenon (Z239), (II-22) Voltage-dependent sodium channel blockers: Select from the following classes, (II-22A) Oxadiazine derivatives: including indoxacarb (Z240); or (II-22B) Semicarbazone: including metaflumizone (Z241); or (II-22C)1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(difluoromethoxy)phenyl]urea (Z242), (II-22D)2-[3-(ethanesulfonyl)pyridine-2-yl]-5-[trifluoro(methanesulfonyl)]-1,3-benzoxazole(oxazosulfyl)(Z243), (II-23) Acetyl-CoA carboxylase inhibitors: Selected from the classes of tetronic acid and tetramic acid derivatives: including spirodiclofen (Z244), spiromesifen (Z245), spiropidione (Z246), and spirotetramat (Z247), (II-24) Mitochondrial electron transport chain complex IV inhibitors: Select from the following classes, (II-24A) Phosphine-based: containing aluminum phosphide (Z248), calcium phosphide (Z249), phosphine (Z250), and zinc phosphide (Z251); or (II-24B) Cyanides: containing calcium cyanide (Z252), potassium cyanide (Z253), and sodium cyanide (Z254), (II-25) Mitochondrial electron transport chain complex II inhibitors: Select from the following classes, (II-25A) Beta-ketonitrile derivatives: containing cyenopyrafen (Z255) and cyflumetofen (Z256), or (II-25B) Carboxanilide series: including piflubum (Z257), (II-26) Rianodine receptor modulators: From the diamide class: flubendiamide (Z258), chlorantraniliprole (Rynaxypyr®) (Z259), cyantraniliprole (Cyazypyr®) (Z260), cyclaniliprole (Z260), tetraniliprole (Z261), tetrachlorantraniliprole (Z262), (R)-3-chlor-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-(tetrafluor-)1-(trifluoromethyl(trifluor methyl))ethyl]phenyl}-N2-(1-methyl-2-methylsulfonylethyl)phthalamide (phthalamid) (Z263); (S)-3-chlor-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}-N2-(1-methyl-2-methylsulfonylethyl)phthalamide (Z264); methyl-2-[3,5-dibromo-2-({[3-bromo-1-(3-chlorpyridine-2-yl)-1H-pyrazole-5-yl]carbonyl}aminobenzoyl]-1,2-di Methylhydrazine carboxylate (Z265); N-[2-(5-amino-1,3,4-thiadiazole-2-yl)-4-chloro-6-methyl-phenyl]-5-bromo-2-(3-chloro-2-pyridyl)pyrazole-3-carboxamide (Z266); 5-chloro-2-(3-chloro-2-pyridyl)-N-[2,4-dichloro-6-[(1-cyano-1-methyl-ethyl)carbamoyl]phenyl]pyrazole-3-carboxamide (Z267); 5-bromo-N-[2,4-dichloro-6-(methylcarbamoyl)phenyl]-2-(3, The following are included: 5-dichloro-2-pyridyl)pyrazole-3-carboxamide (Z268); N-[2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl]-2-(3-chloro-2-pyridyl)-5-(fluoromethoxy)pyrazole-3-carboxamide (Z269); N2-(1-cyano-1-methyl-ethyl)-N1-(2,4-dimethylphenyl)-3-iodophthalamide (Z270); and 3-chloro-N2-(1-cyano-1-methyl-ethyl)-N1-(2,4-dimethylphenyl)phthalamide (Z271), (II-27) Chord organ modulator - Target site unspecified: Including flonicamide (Z272), (II-28) GABAergic chloride ion channel allosteric modulator: Select from the following classes, (II-28A) Meta-diamide system: containing brofranilide (Z273); or (II-28B) Isoxazoline derivatives: including fluxamethamide (Z274); isocycloceram (Z275), (II-29) Baculovirus: Select from the following classes, (II-29A) Granulopathy virus (GV): including Cydia pomonella GV (Z276) and Thaumatotibia leucotreta GV (Z277); or (II-29B) Nuclear polyhedron disease viruses (NPV): including anticarsia gemmatalis MNPV (Z278) and helicoverpa armigera NPV (Z279), (II-30) Nicotinic acetylcholine receptor (nAChR) allosteric modulator - Site II: Contains GS omega / kappa HXTX-Hv1a peptide (Z280), (II-31) Insecticidal compounds with unknown or unclear mechanisms of action: including the following, Afidopiropene (Z281), azadirachtin (Z282), amidoflumet (Z283), benzoximate (Z284), benzpyrimoxane (Z285), bifenazate (Z286), bromopropylate (Z287), quinomethionate (Z288), cryolite (Z289), dicofol (Z290), fluphenerim (Z291), flomethquine (Z292), fluhexaphon (Z293), fluensulfone (Z294), flupyradiflon (Z295), Lime sulfur (Z296), mancozeb (Z297), piperonyl butoxide (Z298), pyridaryl (Z299), pyrifluquinazone (Z300), sulfoxaflor (Z301), sulfur (Z302), 4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydro-isoxazole-3-yl]-2-methyl-N-[(2,2,2-trifluoro-ethylcarbamoyl)-methyl]-benzamide (Z303); cyclopropaneacetic acid (Z304); 1,1'-[( 3S,4R,4aR,6S,6aS,12R,12aS,12bS)-4-[[(2-cyclopropylacetyl)oxy]methyl]-1,3,4,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-4,6a,12b-trimethyl-11-oxo-9-(3-pyridinyl)-2H,11H-naphtho[2,1-b]pyrano[3,4-e]pyran-3,6-diyl]ester (Z305);11-(4-chloro-2,6-dimethylphenyl)-12-hydroxy-1,4-di Oxa-9-azadispiro[4.2.4.2]-tetradeca-11-en-10-one (Z306); 3-(4'-fluoro-2,4-dimethylbiphenyl-3-yl)-4-hydroxy-8-oxa-1-azadispiro[4.5]deca-3-en-2-one (Z307); 1-[2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl]-3-(trifluoromethyl)-1H-1,2,4-triazole-5-amine (Z308); or active substances based on Bacillus firmus (Votivo, II-1582) (Z309); (E / Z)-N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoroacetamide (Z310);(E / Z)-N-[1-[(6-chloro-5-fluoro-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoroacetamide(Z311);(E / Z)-2,2,2-trifluoro-N-[1-[(6-fluoro-3-pyridyl)methyl]-2-pyridylidene]acetamide(Z312);(E / Z)-N-[1-[(6-bromo-3-pyridyl)methyl]-2-pyridylidene]-2,2,2-trifluoroacetamide(Z313);(E / Z)-N-[1-[1-(6-chloro-3-pyridyl) Ethyl]-2-pyridylidene]-2,2,2-trifluoroacetamide (Z314); (E / Z)-N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2-difluoroacetamide (Z315); (E / Z)-2-chloro-N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2-difluoroacetamide (Z316); (E / Z)-N-[1-[(2-chloropyrimidine-5-yl)methyl]-2-pyridylidene]-2,2,2-trifluoroacetamide Mido (Z317); (E / Z)-N-[1-[(6-chloro-3-pyridyl)methyl]-2-pyridylidene]-2,2,3,3,3-pentafluoro-propanamide) (Z318); Triflumezopyrim (Z319); 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-4H-isoxazole-3-yl]-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]naphthalene-1-carboxamide (Z312); 3-[3-chloro-5-(trifluoro [(methyl)phenyl]-4-oxo-1-(pyrimidine-5-ylmethyl)pyrido[1,2-a]pyrimidine-1-ium-2-oleate (Z313); 8-chloro-N-[2-chloro-5-methoxyphenyl)sulfonyl]-6-trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxamide (Z314); 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isoxazole-3-yl]-2-methyl-N-(1-oxothietan-3-yl)benzamide (Z315);5-[3-[2,6-dichloro-4-(3,3-dichloroallyloxyl)phenoxy]propoxy]-1H-pyrazole (Z316); dinpropyridaz (Z317); ticlopyrazoflor (Z318) and nicoflurprole (Z319); (II-32) Biological pesticides: Selected from the class of pesticides of microorganisms having insecticidal, acaricidal, molluscicidal and / or nematicidal activity: Bacillus firmus (Z320), Btssp. galleriae, Btssp. kurstaki, Beauveria bassiana (Z321), Burkholderia sp. (Z322), Chromobacterium subtsugae (Z323), Isaria fumosorosea (Z324), Lecanicillium longisporum (Z325), L. muscarium (formerly Verticillium lecanii) (Z326), Metarhizium anisopliae (Z327), M. anisopliae var. acridum (Z328), Paecilomyces fumosoroseus Apopka strain 97(Z329), P.lilacinus(Z330), Paenibacillus poppiliae(Z331), Pasteuria spp.(Z332), P.nishizawae(Z333), P.reneformis(Z334), P.usagae(Z335), Pseudomonas fluorescens(Z336), Steinernema feltiae(Z337), Streptomces galbus(Z338), Wolbachia pipientis(Zap)(Z339), Bacillus amyloliquefaciens(Z373), Bacillus subtilis(Z374), Lecanicillium lecanii(Z375), Purpureocillium lilacinum(Z376) and Burkholderia including rinojenses(Z377), and (II-33) Biochemical pesticides having insecticidal, acaricidal, molluscicidal, pheromone, and / or nematicidal activity: L-Carvone (Z340); Citral (Z341); (E,Z)-7,9-Dodecadiene-1-yl acetate (Z342); Ethyl formate (Z343); (E,Z)-2,4-Decadienoyl (pear ester) (Z344); (Z,Z,E)-7,11,13-Hexadecatrienal (Z345); Heptyl butyrate (Z346); Isopropyl myristate (Z347); Lavanduryl senesioate (lavanulyl (Z348) senecioate; 2-methyl-1-butanol (Z349); methyl eugenol (Z350); methyl jasmonate (Z351); (Z)-2,13-octadecadiene-1-ol (Z352); (Z)-2,13-octadecadiene-1-ol acetate (Z353); (Z)-3,13-octadecadiene-1-ol (Z354), R-1-octen-3-ol (Z355); pentatermanone (Z356); potassium silicate (Z357); sorbitol octanoate actanoate)(Z358); (E,Z,Z)-3,8,11-tetradecatrienylate(Z359); (Z,E)-9,12-tetradecadien-1-ylacetate(Z360); Z-7-tetradecen-2-one(Z361), Z-9-tetradecen-1-ylacetate(Z362); Z-11-tetradecenal(Z363); Z-11-tetradecen-1-ol(Z364); Acacia negra extract(Z365); Grapefruit seed and pulp extract(Z366); Chenopodium Contains extract of ambrosiodae (Z367); fatty acid monoesters having glycerol or propanediol (Z368); catnip oil (Z369); neem oil (Z370); quillaja extract (Z371); and tagetes oil (Z372). It is at least one insecticidal compound (II) selected from the group consisting of the following.

[0031] In particular, the thiethanyl oxy compound of formula (I) contained as component (1) in the pesticide mixture is

[0032] [ka] [In the formula, R 1 This is selected from the group consisting of methyl, ethyl, isopropyl, tert-butyl, cyclopropyl, methylcyclopropyl, cyclopropylmethyl, and cyclopropylethyl. R 2 It is hydrogen, R 3 It is selected from the group consisting of chlorine and cyano, R 4 It is selected from the group consisting of methyl, chlorine, and bromine. R 5 It is selected from the group consisting of hydrogen, fluorine, and chlorine. R 6 [Selected from the group consisting of hydrogen and methyl] or agriculturally acceptable salts, isomers / structural isomers, stereoisomers, diastereomers, enantiomers, tautomers, metal complexes, polymorphs, or N-oxides thereof.

[0033] More specifically, the thiethanyl oxy compound of formula (I) is (I-1)N-(2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl)-1-(3-chloropyridine-2-yl)-3-((1,1-dioxidethiethane-3-yl)oxy)-1H-pyrazole-5-carboxamide; (I-2)N-(2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl)-1-(3-chloropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-carboxamide; (I-3)N-(2-(tert-butylcarbamoyl)-4-cyano-6-methylphenyl)-1-(3,5-dichloropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-carboxamide; (I-4)N-(4-chloro-2-(isopropylcarbamoyl)-6-methylphenyl)-1-(3-chloropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-carboxamide; (I-5)N-(2-(tert-butylcarbamoyl)-4-cyano-6-methylphenyl)-1-(3-chloropyridine-2-yl)-3-((3-methylthietan-3-yl)oxy)-1H-pyrazole-5-carboxamide; (I-6)N-(2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl)-1-(3,5-dichloropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-carboxamide; (I-7)N-(2-(tert-butylcarbamoyl)-4-cyano-6-methylphenyl)-1-(3-chloropyridine-2-yl)-3-((3-methyl-1,1-dioxidethiethane-3-yl)oxy)-1H-pyrazole-5-carboxamide; (I-8)1-(3-chloropyridine-2-yl)-N-(2,4-dichloro-6-(isopropylcarbamoyl)phenyl)-3-((1,1-dioxidethiethane-3-yl)oxy)-1H-pyrazole-5-carboxamide; (I-9)N-(2-bromo-4-chloro-6-(isopropylcarbamoyl)phenyl)-1-(3-chloropyridine-2-yl)-3-((1,1-dioxidethiethane-3-yl)oxy)-1H-pyrazole-5-carboxamide; (I-10)N-(4-chloro-2-(cyclopropylcarbamoyl)-6-methylphenyl)-1-(3-chloro-5-fluoropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-carboxamide; and (I-11)N-(4-chloro-2-(isopropylcarbamoyl)-6-methylphenyl)-1-(3,5-dichloropyridine-2-yl)-3-((1,1-dioxidethiethane-3-yl)oxy)-1H-pyrazole-5-carboxamide It is selected from the group consisting of the following.

[0034] In a preferred embodiment, the biotoxic mixture according to the present invention comprises component (2), (II-2) GABAergic chloride ion channel blockers; (II-3) Sodium channel modulators (pyrethroid / pyrethrin); (II-4) Competitive modulators of nicotinic acetylcholine receptors (nAChR); (II-5) Nicotinic acetylcholine receptor (nAChR) allosteric modulator - site I; (II-6) Glutamate-gated chloride ion channel (GluCl) allosteric modulator; (II-7) Juvenile hormone mimetic; (II-9) String organ TRPV channel modulator; (II-11) Microbial-derived insect midgut endometrium disruptor; (II-13) Oxidative phosphorylation uncoupling agents via disruption of the proton gradient; (II-22) Voltage-dependent sodium channel blockers; (II-28) GABAergic chloride ion channel allosteric modulator; and (II-31) Insecticidal compounds with unknown or unclear mechanisms of action It contains at least one insecticidal compound (II) selected from the following.

[0035] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from acetylcholinesterase (AChE) inhibitors of group (II-1) defined above, particularly organophosphorus compounds of (II-1B), with acephate (Z027) being particularly preferred.

[0036] In one embodiment, the insecticidal mixture according to the invention contains component (2) as an insecticidal compound of formula (II) selected from the pyropenes of group (II-9B) defined above, with afidopyropene (Z190) being particularly preferred.

[0037] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from the above-defined group (II-2) GABAergic chloride ion channel blockers, particularly group (II-2B)-phenylpyrazoles (fiproles), with fipronil (Z095) being particularly preferred.

[0038] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from the sodium channel modulators of group (II-3) defined above, particularly group (II-3A) (pyrethroid / pyrethrin), with bifenthrin (Z103) and cypermethrin (Z113) being particularly preferred.

[0039] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from glutamate-gated chloride ion channel (GluCl) allosteric modulators of the above-defined group (II-6), particularly avermectin / milbemycin systems, with abamectin (Z166) and emamectin benzoate (Z167) being particularly preferred.

[0040] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from the GABAergic chloride ion channel allosteric modulators of the above-defined group (II-28), particularly the meta-diamide system of (II-28A), with broflanilide (Z273) being particularly preferred.

[0041] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from the GABAergic chloride ion channel allosteric modulators of group (II-28) defined above, particularly the (II-28B) isoxazoline series, with fluxamethamide (Z274) being particularly preferred.

[0042] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from the group of insecticidal compounds whose mechanism of action is unknown or unclear as defined above, of which benzpyrimoxane (Z285), fromethoquin (Z292), pyridaryl (Z299), zinpropyridaz (Z317), ticlopyrazoflor (Z318), isocycloceram (Z275), and fluhexaphon (Z293).

[0043] In one embodiment, the insecticidal bioactive mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from oxidative phosphorylation uncoupling agents via disruption of the proton gradient of the above-defined group (II-13), particularly the pyrrole systems of (II-13A), with chlorfenapyr (Z203) being particularly preferred.

[0044] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from nicotinic acetylcholine receptor (nAChR) competitive modulators of the above-defined group (II-4), particularly neonicotinoids of (II-4A), with clothianidin (Z149), imidacloprid (Z151), and thiamethoxam (Z154) being particularly preferred.

[0045] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from the nicotinic acetylcholine receptor (nAChR) competitive modulators of group (II-4) defined above, with flupyrimine (Z163) of (II-4F) being particularly preferred.

[0046] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from nicotinic acetylcholine receptor (nAChR) competitive modulators of the above-defined group (II-4), particularly mesoionic systems of (II-4E), with triflumezopyrim (Z161) being particularly preferred.

[0047] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from the mitochondrial ATP synthase inhibitors of group (II-12) defined above, particularly (II-12A) diafenthiurone (Z197).

[0048] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from voltage-dependent sodium channel blockers of group (II-22) defined above, particularly the oxadiazine system of (II-22A), with indoxacarb (Z240) being particularly preferred.

[0049] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from voltage-dependent sodium channel blockers of group (II-22) defined above, particularly the semicarbazone system of (II-22B), with metaflumizone (Z241) being particularly preferred.

[0050] In one embodiment, the biocidal mixture according to the invention is an insecticidal compound of formula (II) selected from voltage-dependent sodium channel blockers of the above-defined group (II-22), particularly oxazosulfyl (Z243) of (II-22D).

[0051] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from chordophonic organ TRPV channel modulators of the defined group (II-9), particularly pyridineazomethine derivatives of (II-9A), with pyrometrozine (Z188) being particularly preferred.

[0052] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from the juvenile hormone mimes of group (II-7) defined above, with pyriproxyfen (Z174) of (II-7C) being particularly preferred.

[0053] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from acetyl-CoA carboxylase inhibitors of the above-defined group (II-23), particularly tetronic acid and tetramic acid derivatives, with spirodiclofen (Z244) and spiropidione (Z246) being particularly preferred.

[0054] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from the nicotinic acetylcholine receptor (nAChR) allosteric modulator-site I of the above-defined group (II-5), particularly the spinosin system, with spinetram (Z164) and spinosad (Z165) being particularly preferred.

[0055] In one embodiment, the biotoxic mixture according to the invention comprises component (2) as an insecticidal compound of formula (II) selected from chitin biosynthesis inhibitors, particularly benzoylureas, that act on CHS1 of the above-defined group (II-15), with teflubenzuron (Z219) being particularly preferred.

[0056] In one embodiment, the biotoxic mixture according to the invention comprises a component (2) selected from the insect midgut endometrium disruptors of microorganisms of the above-defined group (II-11), with Bacillus thuringinienses being particularly preferred.

[0057] In preferred embodiments, the biotoxic mixture according to the present invention includes abamectin (Z166), acephate (Z027), acetamiprid (Z148), afidopiropene (Z190), alpha-cypermethrin (Z114), bifenthrin (Z103), broflanilide (Z273), benzpyrimoxane (Z285), buprofezin (Z221), and chlorfe. Napil (Z203), Clothianidin (Z149), Cyhalothrin (Z110), Cypermethrin (Z113), Diafenthiuron (Z197), Zinpropyridaz (Z3170), Dinotefuran (Z150), Emamectin Benzoate (Z167), Flunicamide (Z272), Fluxamethamide (Z274), Flupyrimin (Z163), Fipronil (Z095) Fluhexaphon (Z293), Flomethkin (Z292), Imidaclopride (Z151), Indoxacarb (Z240), Isocycloseram (Z275), Metaflumizone (Z241), Oxazosulfyl (Z243), Pyridaryl (Z299), Pymetrozine (Z188), Pyriproxyfen (Z174), Spirodiclofen (Z244), Spiropizo The compound comprises component (2) as at least one insecticidal compound of formula (II) selected from n (Z246), spinetoram (Z164), spinosad (Z165), spirotetramat (Z247), thiamethoxam (Z154), teflubenzuron (Z219), thiacloprid (Z153), triflumezopyrim (Z161), and ticlopyrazoflor (Z318).

[0058] In a preferred embodiment, the biocidal mixture according to the present invention comprises at least one biological pesticide selected from (2) azadirachtin (Z282), Bacillus firmus (Z320), Bacillus thuringinienses (Z195), Bacillus amyloliquefaciens (Z373), Bacillus subtilis (Z374), Beauveria bassiana (Z321), Lecanicillium lecanii (Z375), Metarhizium anisopliae (Z327), Purpureocillium lilacinum (Z376), and Burkholderia rinojenses (Z377).

[0059] In another embodiment, the present invention provides component (1) of formula (I)

[0060] [ka] [In the formula, R 1 This is selected from the group consisting of C1-C6 alkyl, C3-C5 cycloalkyl, C3-C5 cycloalkyl-C1-C6 alkyl, and C1-C6 alkyl-C3-C5 cycloalkyl. R 2 It is selected from the group consisting of hydrogen and methyl, R 3 It is selected from the group consisting of fluorine, chlorine, bromine, and cyano, R 4 It is selected from the group consisting of methyl, fluorine, chlorine, bromine, and trifluoromethyl, R 5 It is selected from the group consisting of hydrogen, fluorine, and chlorine. R 6 [Selected from the group consisting of hydrogen, methyl, and trifluoromethyl] As thietanyloxy compounds or their agriculturally acceptable salts, isomers / structural isomers, stereoisomers, diastereomers, enantiomers, tautomers, metal complexes, polymorphs, or N-oxides; Furthermore, component (2) (A) Ergosterol biosynthesis inhibitors: (A001) Cyproconazole; (A002) Diphenconazole; (A003) Epoxyconazole; (A004) Fenhexamide; (A005) Fenpropidine; (A006) Fenpropimorph; (A007) Fenpyrazamine; (A008) Fluquinconazole; (A009) Flutriafoll; (A010) Imazalil; (A011) Imazalil sulfate; (A012) Ipconazole; (A013) Metconazole; (A014) Mycrobutanil; (A015) Paclobutrazol; (A01 6) Prochloraz; (A017) Propiconazole; (A018) Prothioconazole; (A019) Pyrisoxazole; (A020) Spiroxamine; (A021) Tebuconazole; (A022) Tetraconazole; (A023) Triadimenol; (A024) Tridemorph; (A025) Triticonazole; (A026) (1R,2S,5S)-5-(4-Chlorobenzyl)-2-(Chloromethyl)-2-methyl-1-(1H-1,2,4-Triazole-1-ylmethyl)cyclopentanol; (A027) (1S,2R,5R)-5-(4 -Chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazole-1-ylmethyl)cyclopentanol, (A028)(2R)-2-(1-chlorocyclopropyl)-4-[(1R)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazole-1-yl)butan-2-ol; (A029)(2R)-2-(1-chlorocyclopropyl)-4-[(1S)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazole-1-yl)butan-2-ol; (A030)(2R )-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazole-1-yl)propan-2-ol; (A031)(2S)-2-(1-chlorocyclopropyl)-4-[(1R)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazole-1-yl)butan-2-ol; (A032)(2S)-2-(1-chlorocyclopropyl)-4-[(1S)-2,2-dichlorocyclopropyl]-1-(1H-1,2,4-triazole-1-yl)butan-2-ol;(A033)(2S)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazole-1-yl)propan-2-ol; (A034)(R)-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl](pyridine-3-yl)methanol; (A035)(S)-[3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl](pyridine-3-yl)methanol (A036) [3-(4-chloro-2-fluorophenyl)-5-(2,4-difluorophenyl)-1,2-oxazol-4-yl](pyridine-3-yl)methanol; (A037) 1-({(2R,4S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl)-1H-1,2,4-triazole; (A038) 1-({(2S,4S)-2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl}methyl )-1H-1,2,4-triazole;(A039)1-{[3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole-5-ylthiocyanate;(A040)1-{[rel(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole-5-ylthiocyanate;(A041)1-{[rel(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluoro (A042)2-[(2R,4R,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thion; (A043)2-[(2R,4R,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thion;(A044)2-[(2R,4S,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thion;(A045)2-[(2R,4S,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thion;(A046)2-[(2S,4R,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2, 6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thion;(A047)2-[(2S,4R,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thion;(A048)2-[(2S,4S,5R)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3- Thione; (A049) 2-[(2S,4S,5S)-1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thion; (A050) 2-[1-(2,4-dichlorophenyl)-5-hydroxy-2,6,6-trimethylheptan-4-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thion; (A051) 2-[2-chloro-4-(2,4-dichlorophenoxy)phenyl]-1-(1H-1,2,4-triazole (A052) 2-[2-chloro-4-(4-chlorophenoxy)phenyl]-1-(1H-1,2,4-triazole-1-yl)butan-2-ol; (A053) 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazole-1-yl)butan-2-ol; (A054) 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazole-1-yl)pentan-2-ol;(A055)2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazole-1-yl)propan-2-ol;(A056)2-{[3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thion;(A057)2-{[rel(2R,3R)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro- 3H-1,2,4-triazole-3-thion; (A058)2-{[rel(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thion; (A059)5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazole-1-ylmethyl)cyclopentanol; (A060)5-(allylsulfanil)-1-{[3-(2-chlorophenyl)-2-(2,4-difluoromethyl]methyl}-2,4-dihydro-3H-1,2,4-triazole-3-thion; (A059)5-(4-chlorobenzyl)-2-(chloromethyl)-2-methyl-1-(1H-1,2,4-triazole-1-ylmethyl)cyclopentanol; (A060)5-(arylsulfanil)-1-{[3-(2-chlorophenyl)-2-(2,4-difluoromethyl]methyl} (A061) 5-(allylsulfanil)-1-{[rel(2R,3R)-3-2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole; (A062) 5-(allylsulfanil)-1-{[rel(2R,3S)-3-(2-chlorophenyl)-2-(2,4-difluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole; (A063) N'- (2,5-dimethyl-4-{[3-(1,1,2,2-tetrafluoroethoxy)phenyl]sulfanyl}phenyl)-N-ethyl-N-methylimidoformamide; (A064)N'-(2,5-dimethyl-4-{[3-(2,2,2-trifluoroethoxy)phenyl]sulfanyl}phenyl)-N-ethyl-N-methylimidoformamide; (A065)N'-(2,5-dimethyl-4-{[3-(2,2,3,3-tetrafluoropropoxy)phenyl]sulfanyl}phenyl)-N-ethyl-N-methylimidoformamide;(A066)N'-(2,5-dimethyl-4-{[3-(pentafluoroethoxy)phenyl]sulfanyl}phenyl)-N-ethyl-N-methylimidoformamide; (A067)N'-(2,5-dimethyl-4-{3-[(1,1,2,2-tetrafluoroethyl)sulfanyl]phenoxy}phenyl)-N-ethyl-N-methylimidoformamide; (A068)N'-(2,5-dimethyl-4-{3-[(2,2,2-trifluoroethyl)sulfanyl]phenoxy}phenyl)-N-ethyl-N-methyl Imidoformamide; (A069)N'-(2,5-dimethyl-4-{3-[(2,2,3,3-tetrafluoropropyl)sulfanyl]phenoxy}phenyl)-N-ethyl-N-methylimidoformamide; (A070)N'-(2,5-dimethyl-4-{3-[(pentafluoroethyl)sulfanyl]phenoxy}phenyl)-N-ethyl-N-methylimidoformamide; (A071)N'-(2,5-dimethyl-4-phenoxyphenyl)-N-ethyl-N-methylimidoformamide; (A072)N'- (4-{[3-(difluoromethoxy)phenyl]sulfanyl}-2,5-dimethylphenyl)-N-ethyl-N-methylimidoformamide; (A073)N'-(4-{3-[(difluoromethyl)sulfanyl]phenoxy}-2,5-dimethylphenyl)-N-ethyl-N-methylimidoformamide; (A074)N'-[5-bromo-6-(2,3-dihydro-1H-inden-2-yloxy)-2-methylpyridine-3-yl]-N-ethyl-N-methylimidoformamide; (A075)N'-{4 -[(4,5-dichloro-1,3-thiazole-2-yl)oxy]-2,5-dimethylphenyl}-N-ethyl-N-methylimidoformamide; (A076)N'-{5-bromo-6-[(1R)-1-(3,5-difluorophenyl)ethoxy]-2-methylpyridine-3-yl}-N-ethyl-N-methylimidoformamide; (A077)N'-{5-bromo-6-[(1S)-1-(3,5-difluorophenyl)ethoxy]-2-methylpyridine-3-yl}-N-ethyl-N-methylimidoformamide;(A078) N'-{5-bromo-6-[(cis-4-isopropylcyclohexyl)oxy]-2-methylpyridine-3-yl}-N-ethyl-N-methylimidoformamide; (A079) N'-{5-bromo-6-[(trans-4-isopropylcyclohexyl)oxy]-2-methylpyridine-3-yl}-N-ethyl-N-methylimidoformamide; (A080) N'-{5-bromo-6-[1-(3,5-difluorophenyl)ethoxy]-2-methylpyridine-3-yl}-N-ethyl-N-methylimidoformamide; (A081) mefentrifluconazole; (A0; 82) Ipfentrifluconazole; (A083) 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazole-1-yl)-1-[1-(2,6-difluoro-4-chlorophenoxy)cyclopropyl]ethanol; and (A084) 1-[2-(1-chlorocyclopropyl)-3-(2-fluorophenyl)-2-hydroxypropyl]-1H-imidazole-5-carbonitride, (B) Respiratory chain complex I or II inhibitors: (B001) Benzovindiflupir; (B002) Bixafen; (B003) Boscalid; (B004) Carboxine; (B005) Fluopyram; (B006) Flutolanil; (B007) Fluxapiroxad; (B008) Flamethopyr; (B009) Isofetamide; (B010) Isopyrazam (anti-epimer enantiomer 1R, 4S, 9S); (B011) Isopyrazam (anti-epimer enantiomer 1S, 4R, 9R); (B012) Isopyrazam (anti-epimer racemic 1R) S,4SR,9SR); (B013) Isopyrazam (mixture of syn-epimarasemiform 1RS,4SR,9RS and anti-epimarasemiform 1RS,4SR,9SR); (B014) Isopyrazam (syn-epimer enantiomer 1R,4S,9R); (B015) Isopyrazam (syn-epimer enantiomer 1S,4R,9S); (B016) Isopyrazam (syn-epimarasemiform 1RS,4SR,9RS); (B017) Penflufen; (B018) Penthiopyrad; (B019) Pidiflumetofen; (B02 0) Pyraziflumid; (B021) Sedaxane; (B022) 1,3-Dimethyl-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1H-pyrazole-4-carboxamide; (B023) 1,3-Dimethyl-N-[(3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1H-pyrazole-4-carboxamide; (B024) 1,3-Dimethyl-N-[(3S)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1H-pyrazole -4-carboxamide; (B025) 1-methyl-3-(trifluoromethyl)-N-[2'-(trifluoromethyl)biphenyl-2-yl]-1H-pyrazole-4-carboxamide; (B026) 2-fluoro-6-(trifluoromethyl)-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)benzamide; (B027) 3-(difluoromethyl)-1-methyl-N-(1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1H-pyrazole-4-carboxamide;(B028) 3-(difluoromethyl)-1-methyl-N-[(3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1H-pyrazole-4-carboxamide; (B029) 3-(difluoromethyl)-1-methyl-N-[(3S)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1H-pyrazole-4-carboxamide; (B030) 3-(difluoromethyl)-N-(7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1 -Methyl-1H-pyrazole-4-carboxamide (fluindapyr); (B031) 3-(difluoromethyl)-N-[(3R)-7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1-methyl-1H-pyrazole-4-carboxamide; (B032) 3-(difluoromethyl)-N-[(3S)-7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl]-1-methyl-1H-pyrazole-4-carboxamide; (B033) 5,8-difluoro-N-[ 2-(2-fluoro-4-{[4-(trifluoromethyl)pyridine-2-yl]oxy}phenyl)ethyl]quinazoline-4-amine; (B034)N-(2-cyclopentyl-5-fluorobenzyl)-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1-H-pyrazole-4-carboxamide; (B035)N-(2-tert-butyl-5-methylbenzyl)-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; (B036 )N-(2-tert-butylbenzyl)-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; (B037)N-(5-chloro-2-ethylbenzyl)-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; (B038)N-(5-chloro-2-isopropylbenzyl)-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide;(B039)N-[(1R,4S)-9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalene-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide;(B040)N-[(1S,4R)-9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalene-5-yl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide;(B041)N-[1-(2,4-dichlorophenyl)-1-methoxypropane-2- [Iyl]-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide; (B042)N-[2-chloro-6-(trifluoromethyl)benzyl]-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; (B043)N-[3-chloro-2-fluoro-6-(trifluoromethyl)benzyl]-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; (B044)N-[5-chloro-2- (Trifluoromethyl)benzyl]-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; (B045)N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-N-[5-methyl-2-(trifluoromethyl)benzyl]-1H-pyrazole-4-carboxamide; (B046)N-cyclopropyl-3-(difluoromethyl)-5-fluoro-N-(2-fluoro-6-isopropylbenzyl)-1-methyl-1H-pyrazole-4-carboxamide Mido; (B047) N-cyclopropyl-3-(difluoromethyl)-5-fluoro-N-(2-isopropyl-5-methylbenzyl)-1-methyl-1H-pyrazole-4-carboxamide; (B048) N-cyclopropyl-3-(difluoromethyl)-5-fluoro-N-(2-isopropylbenzyl)-1-methyl-1H-pyrazole-4-carbothioamide; (B049) N-cyclopropyl-3-(difluoromethyl)-5-fluoro-N-(2-isopropylbenzyl)-1-methyl-1H-pyrazole-4-carboxamide;(B050) N-Cyclopropyl-3-(difluoromethyl)-5-fluoro-N-(5-fluoro-2-isopropylbenzyl)-1-methyl-1H-pyrazole-4-carboxamide; (B051) N-Cyclopropyl-3-(difluoromethyl)-N-(2-ethyl-4,5-dimethylbenzyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; (B052) N-Cyclopropyl-3-(difluoromethyl)-N-(2-ethyl-5-fluorobenzyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; (B053) N-Cyclopropyl-3-(difluoromethyl)-N-(2-ethyl-5-methylbenzyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; (B054) N-Cyclopropyl-N-( (B055) N-cyclopropyl-N-(2-cyclopropyl-5-methylbenzyl)-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; (B056) N-cyclopropyl-N-(2-cyclopropyl-5-methylbenzyl)-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; (B057) 2-(difluoromethyl)-N-(1,1-dimethyl-3-propyl-2,3-dihydro-1H-indene-4-yl)nicotinamide; (B058) pyrapropoine; (B059) impilfluxam; and (B060) isoflucipram; (C) Respiratory chain complex III inhibitors: (C001) Ametoctrazine; (C002) Amisulbrom; (C003) Azoxystrobin; (C004) Cumethoxystrobin; (C005) Cumethoxystrobin; (C006) Cyazofamide; (C007) Dimoxystrobin; (C008) Enoxastrobin; (C009) Famoxadone; (C010) Fenamidon; (C011) Fluphenoxystrobin; (C012) Fluoxastrobin; (C013) Crezoxime-methyl; (C014) Metminostrobin; (C015) Oryzastro Bin; (C016) Picoxystrobin; (C017) Pyraclostrobin; (C018) Pyramethostrobin; (C019) Pyramethostrobin; (C020) Trifloxystrobin; (C021) (2E)-2-{2-[({[(1E)-1-(3-{[(E)-1-fluoro-2phenylvinyl]oxy}phenyl)ethylidene]amino}oxy)methyl]phenyl}-2-(methoxyimino)-N-methylacetamide; (C022) (2E,3Z)-5-{[1-(4-chlorophenyl)-1H-pyrazole-3-yl]oxy}-2-(methyl Toxyimino)-N,3-dimethylpenta-3-enamide; (C023)(2R)-2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide; (C024)(2S)-2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide; (C025)(3S,6S,7R,8R)-8-benzyl-3-[({3-[(isobutyryloxy)methoxy]-4-methoxypyridine-2-yl}carbonyl)amino]-6-methyl-4,9-dioxo-1,5-di Oxonan-7-yl-2-methylpropanoate (fenpicoxamide); (C026) 2-{2-[(2,5-dimethylphenoxy)methyl]phenyl}-2-methoxy-N-methylacetamide (mandestrobin); (C027) N-(3-ethyl-3,5,5-trimethylcyclohexyl)-3-formamide-2-hydroxybenzamide; (C028) (2E,3Z)-5-{[1-(4-chloro-2-fluorophenyl)-1H-pyrazole-3-yl]oxy}-2-(methoxyimino)-N,3-dimethylpenta-3-enamide;(C029) Methyl {5-[3-(2,4-dimethylphenyl)-1H-pyrazole-1-yl]-2-methylbenzyl}carbamate; (C030) 1-(2-{[1-(4-chlorophenyl)pyrazole-3-yl]oxymethyl}-3-methylphenyl)-1,4-dihydro-4-methyl-5H-tetrazole-5-one (methyltetraprole); and (C031) floryl picoxamide; (D) Mitotic and cell division inhibitors: (D001) Carbendazim; (D002) Dietofencarb; (D003) Etaboxam; (D004) Fluopicolide; (D005) Pencyclon; (D006) Thiabendazole; (D007) Thiophanate-methyl; (D008) Zoxamide; (D009) 3-Chloro-4-(2,6-difluorophenyl)-6-methyl-5-phenylpyridazine; (D010) 3-Chloro-5-(4-chlorophenyl)-4-(2,6-difluorophenyl)-6-methylpyridazine; (D011) 3-C Lolo-5-(6-chloropyridine-3-yl)-6-methyl-4-(2,4,6-trifluorophenyl)pyridazine; (D012)4-(2-bromo-4-fluorophenyl)-N-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine; (D013)4-(2-bromo-4-fluorophenyl)-N-(2-bromo-6-fluorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine; (D014)4-(2-bromo-4-fluorophenyl)-N-(2-bromophenyl)-1,3-dimethyl- 1H-pyrazole-5-amine; (D015) 4-(2-bromo-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine; (D016) 4-(2-bromo-4-fluorophenyl)-N-(2-chlorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine; (D017) 4-(2-bromo-4-fluorophenyl)-N-(2-fluorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine; (D018) 4-(2-chloro-4-fluorophenyl)- N-(2,6-difluorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine; (D019)4-(2-chloro-4-fluorophenyl)-N-(2-chloro-6-fluorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine; (D020)4-(2-chloro-4-fluorophenyl)-N-(2-chlorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine; (D021)4-(2-chloro-4-fluorophenyl)-N-(2-fluorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine;(D022) 4-(4-chlorophenyl)-5-(2,6-difluorophenyl)-3,6-dimethylpyridazine; (D023) N-(2-bromo-6-fluorophenyl)-4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine; (D024) N-(2-bromophenyl)-4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine; and (D025) N-(4-chloro-2,6-difluorophenyl)-4-(2-chloro-4-fluorophenyl)-1,3-dimethyl-1H-pyrazole-5-amine; (E) Compounds capable of multi-site activity: (E001) Bordeaux mixture; (E002) Captafo; (E003) Captan; (E004) Chlorothalonyl; (E005) Copper hydroxide; (E006) Copper naphthenate; (E007) Copper oxide; (E008) Copper oxychloride; (E009) Copper(II) sulfate; (E010) Dithianone; (E011) Dozin; (E012) Forpet; (E013) Mancozeb; (E014) Maneb; (E01 5) Methylam; (E016) Zinc methylam; (E017) Oxine-copper; (E018) Propineb; (E019) Sulfur preparations containing sulfur and calcium polysulfide; (E020) Thiram; (E021) Zineb; (E022) Ziram; and (E023) 6-ethyl-5,7-dioxo-6,7-dihydro-5H-pynolo[3',4':5,6][1,4]didithiino[2,3-c][1,2]thiazole-3-carbonitrile (F) Compounds capable of inducing host defense: (F001) Acibenzolar-S-methyl; (F002) Isothianil; (F003) Probenazole; and (F004) Thiazinil, (G) Amino acid and / or protein biosynthesis inhibitors: (G001) Cyprodinil; (G002) Kasugamycin; (G003) Kasugamycin hydrochloride hydrate; (G004) Oxytetracycline; (G005) Pyrimethanil; (G006) Including 3-(5-fluoro-3,3,4,4-tetramethyl-3,4-dihydroisoquinoline-1-yl)quinoline; (H)ATP production inhibitors: (H001) Silthiofame; (I) Cell wall synthesis inhibitors: (I001) Benciavalicarb; (I002) Dimethomorph; (I003) Flumorph; (I004) Iprovalicarb; (I005) Mandipropamide; (I006) Pirimorph; (I007) Valifenarate; (I008) (2E)-3-(4-tert-butylphenyl)-3-(2-chloropyridine-4-yl)-1-(morpholine-4-yl)propa-2-en-1-one; and (I009) (2Z)-3-(4-tert-butylphenyl)-3-(2-chloropyridine-4-yl)-1-(morpholine-4-yl)propa-2-en-1-one, (J) Lipid and membrane synthesis inhibitors: comprising (J001) propamocarb; (J002) propamocarb hydrochloride; and (J003) tolcrophos-methyl (K) Melanin biosynthesis inhibitors: (K001) Tricyclazole; (K002) 2,2,2-trifluoroethyl{3-methyl-1-[(4-methylbenzoyl)amino]butan-2-yl}carbamate; (L) Nucleic acid synthesis inhibitors: (L001) Benalaxyl; (L002) Benalaxyl-M (Kiralaxyl); (L003) Metalaxyl; and (L004) Metalaxyl-M (Mephenoxam), (M) Signal transduction inhibitors: (M001) fludioxonil; (M002) iprodione; (M003) procymidone; (M004) proquinazide; (M005) quinoxifen; and (M006) vinclozoline, (N) Compounds capable of acting as uncoupling agents: (N001) fluazinam; and (N002) meptyldinocup, (O) Further compounds: (O001) Abscisic acid; (O002) Benzothiazole; (O003) Bethoxazine; (O004) Capsimycin; (O005) Carvone; (O006) Quinomethionate; (O007) Cufraneb; (O008) Cyflufenaamide; (O009) Cymoxanil; (O010) Cyprosulfamide; (O011) Fluthianil; (O012) Fosetyl-aluminum; (O013) Fosetyl-calcium; (O014) Fosetyl-sodium; (O015) Methyl isothiocyanate; (O016) Metraphenone; (O017) Millidiomycin; (O018) Natamycin; (O019) Nickel dimethyldithiocarbamate; (O020) Nitrotar-isopropyl; (O021) Oxamocarb; (O022) Oxathiapiproline; (O023) Oxyphentiin; (O024) Pentachlorophenol and salts; (O025) Phosphorous acid and its salts; (O026) Propamocarb focetylate; (O027) Pyriophenone (Clazafenone); (O028) Tebufloquine; (O029) Tecrophthalam; (O030) Torniphanide; (O031) 1 -(4-{4-[(5R)-5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazole-3-yl]-1,3-thiazole-2-yl}piperidine-1-yl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazole-1-yl]ethanone;(O032)1-(4-{4-[(5S)-5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazole-3-yl]-1,3-thiazole-2-yl}piperidine-1-yl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazole -1-yl]ethanone; (O033) 2-(6-benzylpyridine-2-yl)quinazoline; (O034) 2,6-dimethyl-1H,5H-[1,4]dithiino[2,3-c:5,6-c']dipyrrole-1,3,5,7(2H,6H)-tetraone; (O035) 2-[3,5-bis(difluoromethyl)-1H-pyrazole-1-yl]-1-[4-(4-{5-[2-(propa-2-in-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazole-3-yl}-1,3-thiazole-2-yl)piperidine-1-yl]ethanone;(O036)2-[3,5-bis(difluoromethyl)-1H-pyrazole-1-yl]-1-[4-(4-{5-[2-chloro-6-(propa-2-in-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazol-3-yl}-1,3-thiazole-2-yl)piperidine-1-yl]ethanone; (O037)2-[3,5-bis(difluoromethyl)-1H-pyrazole-1-yl]-1-[4-(4-{5-[2-fluoro-6-(propa-2-in-1-yloxy)phenyl]-4,5-dihydro-1,2-oxazo [3-yl]-1,3-thiazole-2-yl)piperidine-1-yl]ethanone; (O038) 2-[6-(3-fluoro-4-methoxyphenyl)-5-methylpyridine-2-yl]quinazoline; (O039) 2-{(5R)-3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazole-1-yl]acetyl}piperidine-4-yl)-1,3-thiazole-4-yl]-4,5-dihydro-1,2-oxazole-5-yl}-3-chlorophenylmethanesulfonate; (O040) 2-{(5S)-3-[2-( 1-{[3,5-bis(difluoromethyl)-1H-pyrazole-1-yl]acetyl}piperidine-4-yl)-1,3-thiazole-4-yl]-4,5-dihydro-1,2-oxazole-5-yl}-3-chlorophenylmethanesulfonate; (O041)2-{2-[(7,8-difluoro-2-methylquinoline-3-yl)oxy]-6-fluorophenyl}propan-2-ol; (O042)2-{2-fluoro-6-[(8-fluoro-2-methylquinoline-3-yl)oxy]phenyl}propan-2-ol; (O043 )2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazole-1-yl]acetyl}piperidine-4-yl)-1,3-thiazole-4-yl]-4,5-dihydro-1,2-oxazole-5-yl}-3-chlorophenylmethanesulfonate; (O044)2-{3-[2-(1-{[3,5-is(difluoromethyl)-1H-pyrazole-1-yl]acetyl}piperidine-4-yl)-1,3-thiazole-4-yl]-4,5-dihydro-1,2-oxazole-5-yl}phenylmethanesulfonate;(O045) 2-phenylphenol and salt; (O046) 3-(4,4,5-trifluoro-3,3-dimethyl-3,4-dihydroisoquinoline-1-yl)quinoline; (O047) 3-(4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline-1-yl)quinoline (quinohumerine); (O048) 4-amino-5-fluoropyrimidine-2-ol (tautomerized form: 4-amino-5-fluoropyrimidine-2(1H)-one); (O049) 4-oxo-4-[(2-phenylethyl) [Amino]butanoic acid; (O050) 5-amino-1,3,4-thiadiazole-2-thiol; (O051) 5-chloro-N'-phenyl-N'-(propa-2-in-1-yl)thiophene-2-sulfonohydrazide; (O052) 5-fluoro-2-[(4-fluorobenzyl)oxy]pyrimidine-4-amine; (O053) 5-fluoro-2-[(4-methylbenzyl)oxy]pyrimidine-4-amine; (O054) 9-fluoro-2,2-dimethyl-5-(quinoline-3-yl)-2,3-dihydro-1 ,4-benzoxazepine; (O055)buta-3-in-1-yl{6-[({[(Z)-(1-methyl-1H-tetrazole-5-yl)(phenyl)methylene]amino}oxy)methyl]pyridine-2-yl}carbamate; (O056)ethyl(2Z)-3-amino-2-cyano-3-phenylacrylate; (O057)phenazine-1-carboxylic acid; (O058)propyl 3,4,5-trihydroxybenzoate; (O059)quinoline-8-ol; (O060)quinoline-8-ol sulfate ( 2:1); (O061) tert-butyl{6-[({[(1-methyl-1H-tetrazole-5-yl)(phenyl)methylene]amino}oxy)methyl]pyridine-2-yl}carbamate; (O062) 5-fluoro-4-imino-3-methyl-1-[(4-methylphenyl)sulfonyl]-3,4-dihydropyrimidine-2(1H)-one; (O063) fluoxapiproline; (O064) pyridaclomethyl; (O065) ibufluphenoquine; and (O066) aminopyriphene, as well as; (P) Histone deacetylase inhibitors: (P001) N-(1-ethylcyclopropyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]benzamide; (P002) N-(2-isopropylcyclopropyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]benzamide; (P003) N-(2-methylcyclopropyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]benzamide; (P004) N-(1-methylcyclopropyl)-4- [5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]benzamide; (P005)N-(2-ethylcyclopropyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]benzamide; (P006)N-(2,4-difluorophenyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]benzamide; (P007)5-(trifluoromethyl)-3-[4-[[3-(trifluoromethyl)-1,2,4-triazole-1-yl]methyl]phenyl]-1, 2,4-Oxadiazole; (P008) 2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]1,2,4-triazole-3-carbonitride; (P009) Ethyl 1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-carboxylate; (P010) N-Cyclopropyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-carboxy Thamide; (P011) N,N-dimethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-carboxamide; (P012) N-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-carboxamide; (P013) N,N,-dimethyl-H[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]1,2,4-triazole-3-amine;(P014)3-[4-[(5-ethylsulfanyl-1,2,4-triazol-1-yl)methyl]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole; (P015)3-[4-(triazolo[4,5-b]pyridine-1-ylmethyl)phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole; (P016)3-[4-(triazolo[4,5-b]pyridine-2-ylmethyl)phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole; (P017) 3-[4-(triazolo[4,5-b]pyridine-3-ylmethyl)phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole; (P018)methyl 1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-carboxylate; (P019)ethyl 1-[[3-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-carboxylate; (P020)N ,N-diethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-carboxamide; (P021)N-methoxy-N-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-carboxamide; (P022)Propyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-carboxy Rate; (P023) N-Methoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-carboxamide; (P024) N-Ethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-carboxamide; (P025) 1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-carboxamide;(P026) N-Methoxy-1-[1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrazole-4-yl]methanymine; (P027) Ethyl 1-[1-[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]ethyl]pyrazole-4-carboxylate; (P028) 1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrrolidine-2-one; (P029) 1-[[ 4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]piperidine-2-one; (P030) 4-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]morpholine-3-one; (P031) 4,4-dimethyl-2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]isoxazolidine-3-one; (P032) 2-[[4-[5-(trifluoromethyl)-1,2,4-oxa Diazole-3-yl]phenyl]methyl]isoxazolidine-3-one; (P033) 5,5-dimethyl-2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]isoxazolidine-3-one; (P034) 3,3-dimethyl-1[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]piperidine-2-one; (P035) 1-[[2-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3 -yl]phenyl]methyl]pyrrolidine-2-one; (P036) 1-[[2-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]piperidine-2-one; (P037) 2-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]oxazinane-3-one; (P038) 1-[[3-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]piperidine-2-one;(P039)3-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]oxazolidine-2-one; (P040)1-methyl-3-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]imidazolidine-2-one; (P041)1-[[3-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]-3,3-dimethyl-piperidine-2-one; (P042)1-[[3-ful Oro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrrolinidine-2-one; (P043) 2-[[3-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]-4,4-dimethyl-isoxazolidine-3-one; (P044) 2-[[2,3-difluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]isoxazolidine-3-one; (P045) 2-[[3-F Luoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]isoxazolidine-3-one; (P046) 1-[[3-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]azepan-2-one; (P047) N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]propanamide; (P048) 2,2-dimethyl-N-[[4-[5-(trifluoromethyl)-1,2, 4-Oxadiazole-3-yl]phenyl]methyl]buta-3-inamide; (P049)N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]butanamide; (P050)3-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]butanamide; (P051)2-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]propa-2-enamide;(P052) 2-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]butanamide; (P053) 2-methoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]; (P054) 3,3,3-trifluoro-N-[[3-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]propanamide; (P055) 3,3,3-trifluoro-N-[ [2-Fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]propanamide; (P056)N-[[2,3-difluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]butanamide; (P057)N-[[2,3-difluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]-3,3,3-trifluoro-propanamide; (P058)2-(difluoromethyl Xy)-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]acetamide; (P059)2-Methoxy-2-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]propanamide; (P060)1-Methyl-3-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea; (P061)1-Ethyl-1-methyl-3-[[4-[5-(trifluoromethyl (P062) 1-Ethoxy-3-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea; (P063) 1-Methoxy-1-methyl-3-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]; (P064) 1,1-Diethyl-3-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea;(P065) N-Methoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]cyclopropanecarboxamide; (P066) N-Methoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]penta-4-inamide; (P067) N-Methoxy-2-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]propaneamide; (P068) N,2-Dimethoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]propanamide; (P069) N-Cycloprop; Lu-3,3,3-trifluoro-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]propanamide; (P070) 2,2-difluoro-N-(2-methoxyethyl)-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]cyclopropanecarboxamide; (P071) N-ethyl-2-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]propanamide (P072) N-[[3-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]-N-methoxy-propanamide; (P073) 2-methoxy-N-(2,2,2-trifluoroethyl)-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]acetamide; (P074) N-[[2,3-difluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]-N-meth Xycyclopropanecarboxamide; (P075) 2-(difluoromethoxy)-N-methyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]acetamide; (P076) N-ethoxy-2-methoxy-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]propanamide; (P077) N-isopropyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl (P078) 1-Methoxy-3-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea; (P079) 3-Cyclopropyl-1-Methoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea; (P080) 3-Ethoxy-1-Methoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea;(P081) 3-allyl-1-methoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea; (P082) 1-cyclopropyl-3-methoxy-3-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea; (P083) 3-isopropyl-1-methoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea; (P084) 1-methyl Toxy-3-propa-2-inyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea; (P085) 1-[[3-fluoro-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]-1-methoxy-3-methylurea; (P086) 3-(cyclopropylmethyl)-1-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea; (P087) 1-E Tyl-3-(2,2,2-trifluoroethyl)-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea; (P088) 1,3-dimethoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea; (P089) 3-ethyl-1-methoxy-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]urea; (P090) N-methyl-4-[5-(trif (Luoromethyl)-1,2,4-Oxadiazole-3-yl]benzamide; (P091)N-[(E)-Methoxyiminomethyl]-4-[5-(Trifluoromethyl)-1,2,4-Oxadiazole-3-yl]benzamide; (P092)N-[(Z)-Methoxyiminomethyl]-4-[5-(Trifluoromethyl)-1,2,4-Oxadiazole-3-yl]benzamide; (P093)N-[4-[5-(Trifluoromethyl)-1,2,4-Oxadiazole-3-yl]phenyl]cyclopropanecarboxamide;(P094) N-(2-fluorophenyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]benzamide; (P095) 2,2-difluoro-N-methyl-2-[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]acetamide; (P096) N-allyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]acetamide; (P097) N-[(E)-N-methoxy-C-methyl-carbonimidoyl]-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]benzamide; (P098) N-[(Z)-N-methoxy-C-methyl-carbonimidoyl]-4- [5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]benzamide; (P100)N-allyl-N-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]propanamide; (P101)4,4-dimethyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrrolidine-2-one; (P102)N-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]benzenecarbothioamide; and (P103)5-methyl-1-[[4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]phenyl]methyl]pyrrolidine-2-one; The fungicidal compound (III) selected from the group consisting of the following is included: We provide a mixture with pest-killing activity.

[0061] In a preferred embodiment, the biotoxic mixture according to the present invention comprises component (2), (A) Ergosterol synthesis inhibitors; (B) Inhibitors of respiratory chain complex I or II; (C) Respiratory chain complex III inhibitors; (D) Mitotic and cell division inhibitors; (E) Compounds capable of multi-site activity; (L) Nucleic acid synthesis inhibitors; (M) Signal transduction inhibitors; (N) Compounds capable of acting as uncoupling agents; and (P) Histone deacetylase inhibitors It includes at least one fungicidal compound (III) selected from the following.

[0062] In another preferred embodiment, the biotoxic mixture according to the present invention comprises compound (II) (A001) cyproconazole, (A002) diphenconazole, (A003) epoxyconazole, (A006) fenpropimorph, (A009) flutriafoll, (A013) metconazole, (A017) propiconazole, (A018) prothioconazole, (A021) tebuconazole, (A022) tetraconazole, (A081) mefentrifluconazole, (B001) benzovindiflupyr, (B002) bixafen, (B0 05) Fluopyram, (B007) Fluxapyroxad, (B019) Pidiflumetofen, (B30) Fluindapir, (B059) Impilfluxam, (C003) Azoxystrobin, (C012) Fluoxastrobin, (C014) Metminostrobin, (C017) Pyraclostrobin, (C016) Picoxystrobin, (C020) Trifloxystrobin, (C025) (3S,6S,7R,8R)-8-benzyl-3-[({3-[(isobutyryloxy)methoxy]-4-methoxypyridine-2-yl}carbonyl)amino ]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl-2-methylpropanoate (fenpicoxamide), (C030)1-(2-{[1-(4-chlorophenyl)pyrazole-3-yl]oxymethyl}3-methylphenyl)-1,4-dihydro-4-methyl-5H-tetrazole-5-one (methyltetraprole), (D001) carbendazim, (D007) thiophanate-methyl, (E004) chlorothalonil, (E010) dithianone, (E013) mancozeb, (E020) thyram, (F002) isothiani (F003) Probenazole, (L003) Metalaxyl, (M001) Fludioxonil, (N001) Fluazinam, (O022) Oxathiapiproline, (O043) 2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazole-1-yl]acetyl}piperidine-4-yl)-1,3-thiazole-4-yl]-4,5-dihydro-1,2-oxazole-5-yl}-3-chlorophenylmethanesulfonate (fluoxapiproline), (O046) 3-(4,4,5-trifluoro-3,3-dimethyl-3,It contains at least one fungicidal compound selected from (4-dihydroisoquinoline-1-yl)quinoline, (O047)3-(4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline-1-yl)quinoline (quinohumerine), (O065)ipflufenokine, and (P094)N-(2-fluorophenyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]benzamide.

[0063] In a more preferred embodiment, the toxic bioactive mixture according to the present invention comprises component (2) as at least one fungicidal compound (III) selected from (C003) azoxystrobin, (C017) pyraclostrobin, (L003) metalaxyl, (D007) thiophanate-methyl, (B007) fluxapyroxad, (M001) fludioxonil, (F003) probenazole, (F002) isothianil, and (B005) fluopyram.

[0064] The following combinations illustrate specific embodiments of the agricultural chemical compositions according to the present invention.

[0065] The following combinations are listed in Table 1, wherein component (1) is a group represented by formula "(I)" including the compound of formula (I), and compounds I-1, I-2, I-3, I-4, I-5, I-6, I-7, I-8, I-9, I-10, and I-11, and component (2) is selected from groups II-1) to II-33) as defined herein. Table-1: (I)+(II-1A), (I)+(II-1B), (I)+(II-2A), (I)+(II-2B), (I)+(II-3A), (I)+(II-3B), (I)+(II-4A), (I)+(II-4B), (I) +(II-4C), (I)+(II-4D), (I)+(II-4E), (I)+(II-5), (I)+(II-6), (I)+(II-7A), (I)+(II-7B), (I)+(II-7C), (I)+(II- 8A), (I)+(II-8B), (I)+(II-8C), (I)+(II-8D), (I)+(II-8E), (I)+(II-8F), (I)+(II-9A), (I)+(II-9B), (I)+(II-10A) ), (I)+(II-10B), (I)+(II-11A), (I)+(II-12A), (I)+(II-12B), (I)+(II-12C), (I)+(II-12D), (I)+(II-13A), (I)+(I I-13B), (I)+(II-13C), (I)+(II-14), (I)+(II-15), (I)+(II-16), (I)+(II-17), (I)+(II-18), (I)+(II-19), (I)+(II -20A), (I)+(II-20B), (I)+(II-20C), (I)+(II-20D), (I)+(II-21A), (I)+(II-21B), (I)+(II-22A), (I)+(II-22B), (I )+(II-22C), (I)+(II-23), (I)+(II-24A), (I)+(II-24B), (I)+(II-25A), (I)+(II-25B), (I)+(II-26), (I)+(II-27), (I)+(II-28A), (I)+(II-28B), (I)+(II-29A), (I)+(II-29B), (I)+(II-30), (I)+(II-31), (I)+(II-32), (I)+(II-33)

[0066] In particular, the combinations listed in Table-1A, wherein component (1) is a group represented by formula "(I)" including the compound of formula (I), compounds I-1, I-2, I-3, I-4, I-5, I-6, I-7, I-8, I-9, I-10 and I-11, and component (2) is selected from compounds Z001) to Z377) as defined herein. Table-1A:(I)+(Z001)、(I)+(Z002)、(I)+(Z003)、(I)+(Z004)、(I)+(Z005)、(I)+(Z006)、(I)+(Z007)、(I)+(Z008)、(I)+(Z009)、(I)+(Z010)、(I)+(Z011)、(I)+(Z012)、(I)+(Z013)、(I)+(Z014)、(I)+(Z015)、(I)+(Z016)、(I)+(Z017)、(I)+(Z018)、(I)+(Z019)、(I)+(Z020)、(I)+(Z021)、(I)+(Z022)、(I)+(Z023)、I)+(Z024)、(I)+(Z025)、(I)+(Z026)、(I)+(Z027)、(I)+(Z028)、(I)+(Z029)、(I)+(Z030)、(I)+(Z031)、(I)+(Z032)、(I)+(Z033)、(I)+(Z034)、(I)+(Z035)、(I)+(Z036)、(I)+(Z037)、(I)+(Z038)、(I)+(Z039)、(I)+(Z040)、(I)+(Z041)、(I)+(Z042)、(I)+(Z043)、(I)+(Z044)、(I)+(Z045)、(I)+(Z046)、(I)+(Z047)、(I)+(Z048)、(I)+(Z049)、(I)+(Z050)、(I)+(Z051)、(I)+(Z052)、(I)+(Z053)、(I)+(Z054)、(I)+(Z055)、(I)+(Z056)、(I)+(Z057)、(I)+(Z058)、(I)+(Z059)、(I)+(Z060)、(I)+(Z061)、(I)+(Z062)、(I)+(Z063)、(I)+(Z064)、(I)+(Z065)、(I)+(Z066)、(I)+(Z067)、(I)+(Z068)、(I)+(Z069)、(I)+(Z070)、(I)+(Z071)、(I)+(Z072)、(I)+(Z073)、(I)+(Z074)、(I)+(Z075)、(I)+(Z076)、(I)+(Z077)、(I)+(Z078)、(I)+(Z079)、(I)+(Z080)、(I)+(Z081)、(I)+(Z082)、(I)+(Z083)、(I)+(Z084)、(I)+(Z085)、(I)+(Z086)、(I)+(Z087)、(I)+(Z088)、(I)+(Z089)、(I)+(Z090)、(I)+(Z091)、(I)+(Z092)、(I)+(Z093)、(I)+(Z094)、(I)+(Z095)、(I)+(Z096)、(I)+(Z097)、(I)+(Z098)、(I)+(Z099)、(I)+(Z100)、(I)+(Z101)、(I)+(Z102)、(I)+(Z103)、(I)+(Z104)、(I)+(Z105)、(I)+(Z106)、(I)+(Z107)、(I)+(Z108)、(I)+(Z109)、(I)+(Z110)、(I)+(Z111)、(I)+(Z112)、(I)+(Z113)、(I)+(Z114)、(I)+(Z115)、(I)+(Z116)、(I)+(Z117)、(I)+(Z118)、(I)+(Z119)、(I)+(Z120)、(I)+(Z121)、(I)+(Z122)、(I)+(Z123)、(I)+(Z124)、(I)+(Z125)、(I)+(Z126)、(I)+(Z127)、(I)+(Z128)、(I)+(Z129)、(I)+(Z130)、(I)+(Z131)、(I)+(Z132)、(I)+(Z133)、(I)+(Z134)、(I)+(Z135)、(I)+(Z136)、(I)+(Z137)、(I)+(Z138)、I)+(Z139)、(I)+(Z140)、(I)+(Z141)、(I)+(Z142)、(I)+(Z143)、(I)+(Z144)、(I)+(Z145)、(I)+(Z146)、(I)+(Z147)、(I)+(Z148)、(I)+(Z149)、(I)+(Z150)、(I)+(Z151)、(I)+(Z152)、(I)+(Z153)、(I)+(Z154)、(I)+(Z155)、(I)+(Z156)、(I)+(Z157)、(I)+(Z158)、(I)+(Z159)、(I)+(Z160)、(I)+(Z161)、(I)+(Z162)、(I)+(Z163)、(I)+(Z164)、(I)+(Z165)、(I)+(Z166)、(I)+(Z167)、(I)+(Z168)、(I)+(Z169)、(I)+(Z170)、(I)+(Z171)、(I)+(Z172)、(I)+(Z173)、(I)+(Z174)、(I)+(Z175)、(I)+(Z176)、(I)+(Z177)、(I)+(Z178)、(I)+(Z179)、(I)+(Z180)、(I)+(Z181)、(I)+(Z182)、(I)+(Z183)、(I)+(Z184)、(I)+(Z185)、(I)+(Z186)、(I)+(Z187)、(I)+(Z188)、(I)+(Z189)、(I)+(Z190)、(I)+(Z191)、(I)+(Z192)、(I)+(Z193)、(I)+(Z194)、(I)+(Z195)、(I)+(Z196)、(I)+(Z197)、(I)+(Z198)、(I)+(Z199)、(I)+(Z200)、(I)+(Z201)、(I)+(Z202)、(I)+(Z203)、(I)+(Z204)、(I)+(Z205)、(I)+(Z206)、(I)+(Z207)、(I)+(Z208)、(I)+(Z209)、(I)+(Z210)、(I)+(Z211)、(I)+(Z212)、(I)+(Z213)、(I)+(Z214)、(I)+(Z215)、(I)+(Z216)、(I)+(Z217)、(I)+(Z218)、(I)+(Z219)、(I)+(Z220)、(I)+(Z221)、(I)+(Z222)、(I)+(Z223)、(I)+(Z224)、(I)+(Z225)、(I)+(Z226)、(I)+(Z227)、(I)+(Z228)、(I)+(Z229)、(I)+(Z230)、(I)+(Z231)、(I)+(Z232)、(I)+(Z233)、(I)+(Z234)、(I)+(Z235)、(I)+(Z236)、(I)+(Z237)、(I)+(Z238)、(I)+(Z239)、(I)+(Z240)、(I)+(Z241)、(I)+(Z242)、(I)+(Z243)、(I)+(Z244)、(I)+(Z245)、(I)+(Z246)、(I)+(Z247)、(I)+(Z248)、(I)+(Z249)、(I)+(Z250)、(I)+(Z251)、(I)+(Z252)、(I)+(Z253)、(I)+(Z254)、(I)+(Z255)、(I)+(Z256)、(I)+(Z257)、(I)+(Z258)、(I)+(Z259)、(I)+(Z260)、(I)+(Z261)、(I)+(Z262)、(I)+(Z263)、(I)+(Z264)、(I)+(Z265)、(I)+(Z266)、(I)+(Z267)、(I)+(Z268)、(I)+(Z269)、(I)+(Z270)、(I)+(Z271)、(I)+(Z272)、(I)+(Z273)、(I)+(Z274)、(I)+(Z275)、(I)+(Z276)、(I)+(Z277)、(I)+(Z278)、(I)+(Z279)、(I)+(Z280)、(I)+(Z281)、(I)+(Z282)、(I)+(Z283)、(I)+(Z284)、(I)+(Z285)、(I)+(Z286)、(I)+(Z287)、(I)+(Z288)、(I)+(Z289)、(I)+(Z290)、(I)+(Z291)、(I)+(Z292)、(I)+(Z293)、(I)+(Z294)、(I)+(Z295)、(I)+(Z296)、(I)+(Z297)、(I)+(Z298)、(I)+(Z299)、(I)+(Z300)、(I)+(Z301)、(I)+(Z302)、(I)+(Z303)、(I)+(Z304)、(I)+(Z305)、(I)+(Z306)、(I)+(Z307)、(I)+(Z308)、(I)+(Z309)、(I)+(Z310)、(I)+(Z311)、(I)+(Z312)、(I)+(Z313)、(I)+(Z314)、(I)+(Z315)、(I)+(Z316)、(I)+(Z317)、(I)+(Z318)、(I)+(Z319)、(I)+(Z320)、(I)+(Z321)、(I)+(Z322)、(I)+(Z323)、(I)+(Z324)、(I)+(Z325)、(I)+(Z326)、(I)+(Z327)、(I)+(Z328)、(I)+(Z329)、(I)+(Z330)、(I)+(Z331)、(I)+(Z332)、(I)+(Z333)、(I)+(Z334)、(I)+(Z335)、(I)+(Z336)、(I)+(Z337)、(I)+(Z338)、(I)+(Z339)、(I)+(Z340)、(I)+(Z341)、(I)+(Z342)、(I)+(Z343)、(I)+(Z344)、(I)+(Z345)、(I)+(Z346)、(I)+(Z347)、(I)+(Z348)、(I)+(Z349)、(I)+(Z350)、(I)+(Z351)、(I)+(Z352)、(I)+(Z353)、(I)+(Z354)、(I)+(Z355)、(I)+(Z356)、(I)+(Z357)、(I)+(Z358)、(I)+(Z359)、(I)+(Z360)、(I)+(Z361)、(I)+(Z362)、(I)+(Z363)、(I)+(Z364)、(I)+(Z365), (I)+(Z366), (I)+(Z367), (I)+(Z368), (I)+(Z369), (I)+(Z370), (I)+(Z371), (I)+(Z372), (I)+(Z373), (I)+(Z374), (I)+(Z375), (I)+(Z376), and (I)+(Z377). (In one embodiment, in the combinations [(I)+(II-1A)~[(I)+(II-33)] or [(I)+(Z001)]~[(I)+(Z377)] in Table 1, the weight ratio of component (1) to component (2) is between 500:1 and 1:500.)

[0067] In one embodiment, in the combinations [(I)+(II-1A)]~[(I)+(II-33)] or [(I)+(Z001)]~[(I)+(Z377)] shown in Table 1, the weight ratio of component (1) to component (2) is between 100:1 and 1:100.

[0068] In one embodiment, in the combinations [(I)+(II-1A)]~[(I)+(II-33)] or [(I)+(Z001)]~[(I)+(Z377)] shown in Table 1, the weight ratio of component (1) to component (2) is between 50:1 and 1:50.

[0069] In one embodiment, in the combinations [(I)+(II-1A)]~[(I)+(II-33)] or [(I)+(Z001)]~[(I)+(Z377)] shown in Table 1, the weight ratio of component (1) to component (2) is between 20:1 and 1:20.

[0070] In one embodiment, in the combinations [(I)+(II-1A)]~[(I)+(II-33)] or [(I)+(Z001)]~[(I)+(Z377)] shown in Table 1, the weight ratio of component (1) to component (2) is between 5:1 and 1:5.

[0071] In one embodiment, in the combinations [(I)+(II-1A)]~[(I)+(II-33)] or [(I)+(Z001)]~[(I)+(Z377)] shown in Table 1, the weight ratio of component (1) to component (2) is between 3:1 and 1:3.

[0072] In one embodiment, in the combinations [(I)+(II-1A)]~[(I)+(II-33)] or [(I)+(Z001)]~[(I)+(Z377)] in Table 1, the weight ratio of component (1) to component (2) is between 2:1 and 1:2.

[0073] In one embodiment, in the combinations [(I)+(II-1A)]~[(I)+(II-33)] or [(I)+(Z001)]~[(I)+(Z377)] shown in Table 1, the weight ratio of component (1) to component (2) is 1:1.

[0074] The following combinations are listed in Table 2, where component (1) is compound (I-1) and component (2) is selected from groups II-1) to II-33) as defined herein. Table-2: (I-1)+(II-1A)、(I-1)+(II-1B)、(I-1)+(II-2A)、(I-1)+(II-2B)、(I-1)+(II-3A)、(I-1)+(II-3B)、(I-1)+(II-4A)、(I-1)+(II-4B)、(I-1) 1)+(II-4C)、(I-1)+(II-4D)、(I-1)+(II-4E)、(I-1)+(II-5)、(I-1)+(II-6)、(I-1)+(II-7A)、(I-1)+(II-7B)、(I-1)+(II-7C)、(I-1)+(I I-8A)、(I-1)+(II-8B)、(I-1)+(II-8C)、(I-1)+(II-8D)、(I-1)+(II-8E)、(I-1)+(II-8F)、(I-1)+(II-9A)、(I-1)+(II-9B)、(I-1)+(II-1) 0A)、(I-1)+(II-10B)、(I-1)+(II-11A)、(I-1)+(II-12A)、(I-1)+(II-12B)、(I-1)+(II-12C)、(I-1)+(II-12D)、(I-1)+(II-13A)、(I-1)+ (II-13B)、(I-1)+(II-13C)、(I-1)+(II-14)、(I-1)+(II-15)、(I-1)+(II-16)、(I-1)+(II-17)、(I-1)+(II-18)、(I-1)+(II-19)、(I-1)+(I-1) II-20A)、(I-1)+(II-20B)、(I-1)+(II-20C)、(I-1)+(II-20D)、(I-1)+(II-21A)、(I-1)+(II-21B)、(I-1)+(II-22A)、(I-1)+(II-22B)、(I-1) -1)+(II-22C)、(I-1)+(II-23)、(I-1)+(II-24A)、(I-1)+(II-24B)、(I-1)+(II-25A)、(I-1)+(II-25B)、(I-1)+(II-26)、(I-1)+(II-27)、 (I-1)+(II-28A)、(I-1)+(II-28B)、(I-1)+(II-29A)、(I-1)+(II-29B)、(I-1)+(II-30)、(I-1)+(II-31)、(I-1)+(II-32)、(I-1)+(II-33)。

[0075] In particular, the combinations listed in Table 2A where component (1) is compound (I-1) and component (2) is selected from the compounds (Z001) to (Z377) defined herein. Table-2A: (I-1)+(Z001)、(I-1)+(Z002)、(I-1)+(Z003)、(I-1)+(Z004)、(I-1)+(Z005)、(I-1)+(Z006)、(I-1)+(Z007)、(I-1)+(Z008)、(I-1)+(Z009)、(I-1)+(Z010)、(I-1)+(Z011)、(I-1)+(Z012)、(I-1)+(Z013)、(I-1)+(Z014)、(I-1)+(Z015)、(I-1)+(Z016)、(I-1)+(Z017)、(I-1)+(Z018)、(I-1)+(Z019)、(I-1)+(Z020)、(I-1)+(Z021)、(I-1)+(Z022)、(I-1)+(Z023)、I-1)+(Z024)、(I-1)+(Z025)、(I-1)+(Z026)、(I-1)+(Z027)、(I-1)+(Z028)、(I-1)+(Z029)、(I-1)+(Z030)、(I-1)+(Z031)、(I-1)+(Z032)、(I-1)+(Z033)、(I-1)+(Z034)、(I-1)+(Z035)、(I-1)+(Z036)、(I-1)+(Z037)、(I-1)+(Z038)、(I-1)+(Z039)、(I-1)+(Z040)、(I-1)+(Z041)、(I-1)+(Z042)、(I-1)+(Z043)、(I-1)+(Z044)、(I-1)+(Z045)、(I-1)+(Z046)、(I-1)+(Z047)、(I-1)+(Z048)、(I-1)+(Z049)、(I-1)+(Z050)、(I-1)+(Z051)、(I-1)+(Z052)、(I-1)+(Z053)、(I-1)+(Z054)、(I-1)+(Z055)、(I-1)+(Z056)、(I-1)+(Z057)、(I-1)+(Z058)、(I-1)+(Z059)、(I-1)+(Z060)、(I-1)+(Z061)、(I-1)+(Z062)、(I-1)+(Z063)、(I-1)+(Z064)、(I-1)+(Z065)、(I-1)+(Z066)、(I-1)+(Z067)、(I-1)+(Z068)、(I-1)+(Z069)、(I-1)+(Z070)、(I-1)+(Z071)、(I-1)+(Z072)、(I-1)+(Z073)、(I-1)+(Z074)、(I-1)+(Z075)、(I-1)+(Z076)、(I-1)+(Z077)、(I-1)+(Z078)、(I-1)+(Z079)、(I-1)+(Z080)、(I-1)+(Z081)、(I-1)+(Z082)、(I-1)+(Z083)、(I-1)+(Z084)、(I-1)+(Z085)、(I-1)+(Z086)、(I-1)+(Z087)、(I-1)+(Z088)、(I-1)+(Z089)、(I-1)+(Z090)、(I-1)+(Z091)、(I-1)+(Z092)、(I-1)+(Z093)、(I-1)+(Z094)、(I-1)+(Z095)、(I-1)+(Z096)、(I-1)+(Z097)、(I-1)+(Z098)、(I-1)+(Z099)、(I-1)+(Z100)、(I-1)+(Z101)、(I-1)+(Z102)、(I-1)+(Z103)、(I-1)+(Z104)、(I-1)+(Z105)、(I-1)+(Z106)、(I-1)+(Z107)、(I-1)+(Z108)、(I-1)+(Z109)、(I-1)+(Z110)、(I-1)+(Z111)、(I-1)+(Z112)、(I-1)+(Z113)、(I-1)+(Z114)、(I-1)+(Z115)、(I-1)+(Z116)、(I-1)+(Z117)、(I-1)+(Z118)、(I-1)+(Z119)、(I-1)+(Z120)、(I-1)+(Z121)、(I-1)+(Z122)、(I-1)+(Z123)、(I-1)+(Z124)、(I-1)+(Z125)、(I-1)+(Z126)、(I-1)+(Z127)、(I-1)+(Z128)、(I-1)+(Z129)、(I-1)+(Z130)、(I-1)+(Z131)、(I-1)+(Z132)、(I-1)+(Z133)、(I-1)+(Z134)、(I-1)+(Z135)、(I-1)+(Z136)、(I-1)+(Z137)、(I-1)+(Z138)、(I-1)+(Z139)、(I-1)+(Z140)、(I-1)+(Z141)、(I-1)+(Z142)、(I-1)+(Z143)、(I-1)+(Z144)、(I-1)+(Z145)、(I-1)+(Z146)、(I-1)+(Z147)、(I-1)+(Z148)、(I-1-1)+(Z149)、(I-1-1)+(Z150)、(I-1-1)+(Z151)、(I-1-1)+(Z152)、(I-1-1)+(Z153)、(I-1)+(Z154)、(I-1)+(Z155)、(I-1)+(Z156)、(I-1)+(Z157)、(I-1)+(Z158)、(I-1)+(Z159)、(I-1)+(Z160)、(I-1)+(Z161)、(I-1)+(Z162)、(I-1)+(Z163)、(I-1)+(Z164)、(I-1)+(Z165)、(I-1)+(Z166)、(I-1)+(Z167)、(I-1)+(Z168)、(I-1)+(Z169)、(I-1)+(Z170)、(I-1)+(Z171)、(I-1)+(Z172)、(I-1)+(Z173)、(I-1)+(Z174)、(I-1)+(Z175)、(I-1)+(Z176)、(I-1)+(Z177)、(I-1)+(Z178)、(I-1)+(Z179)、(I-1)+(Z180)、(I-1)+(Z181)、(I-1)+(Z182)、(I-1)+(Z183)、(I-1)+(Z184)、(I-1)+(Z185)、(I-1)+(Z186)、(I-1)+(Z187)、(I-1)+(Z188)、(I-1)+(Z189)、(I-1)+(Z190)、(I-1)+(Z191)、(I-1)+(Z192)、(I-1)+(Z193)、(I-1)+(Z194)、(I-1)+(Z195)、(I-1)+(Z196)、(I-1)+(Z197)、(I-1)+(Z198)、(I-1)+(Z199)、(I-1)+(Z200)、(I-1)+(Z201)、(I-1)+(Z202)、(I-1)+(Z203)、(I-1)+(Z204)、(I-1)+(Z205)、(I-1)+(Z206)、(I-1)+(Z207)、(I-1)+(Z208)、(I-1)+(Z209)、(I-1)+(Z210)、(I-1)+(Z211)、(I-1)+(Z212)、(I-1)+(Z213)、(I-1)+(Z214)、(I-1)+(Z215)、(I-1)+(Z216)、(I-1)+(Z217)、(I-1)+(Z218)、(I-1)+(Z219)、(I-1)+(Z220)、(I-1)+(Z221)、(I-1)+(Z222)、(I-1)+(Z223)、(I-1)+(Z224)、(I-1)+(Z225)、(I-1)+(Z226)、(I-1)+(Z227)、(I-1)+(Z228)、(I-1)+(Z229)、(I-1)+(Z230)、(I-1)+(Z231)、(I-1)+(Z232)、(I-1)+(Z233)、(I-1)+(Z234)、(I-1)+(Z235)、(I-1)+(Z236)、(I-1)+(Z237)、(I-1)+(Z238)、(I-1)+(Z239)、(I-1)+(Z240)、(I-1)+(Z241)、(I-1)+(Z242)、(I-1)+(Z243)、(I-1)+(Z244)、(I-1)+(Z245)、(I-1)+(Z246)、(I-1)+(Z247)、(I-1)+(Z248)、(I-1)+(Z249)、(I-1)+(Z250)、(I-1)+(Z251)、(I-1)+(Z252)、(I-1)+(Z253)、(I-1)+(Z254)、(I-1)+(Z255)、(I-1)+(Z256)、(I-1)+(Z257)、(I-1)+(Z258)、(I-1)+(Z259)、(I-1)+(Z260)、(I-1)+(Z261)、(I-1)+(Z262)、(I-1)+(Z263)、(I-1)+(Z264)、(I-1)+(Z265)、(I-1)+(Z266)、(I-1)+(Z267)、(I-1)+(Z268)、(I-1)+(Z269)、(I-1)+(Z270)、(I-1)+(Z271)、(I-1)+(Z272)、(I-1)+(Z273)、(I-1)+(Z274)、(I-1)+(Z275)、(I-1)+(Z276)、(I-1)+(Z277)、(I-1)+(Z278)、(I-1)+(Z279)、(I-1)+(Z280)、(I-1)+(Z281)、(I-1)+(Z282)、(I-1)+(Z283)、(I-1)+(Z284)、(I-1)+(Z285)、(I-1)+(Z286)、(I-1)+(Z287)、(I-1)+(Z288)、(I-1)+(Z289)、(I-1)+(Z290)、(I-1)+(Z291)、(I-1)+(Z292)、(I-1)+(Z293)、(I-1)+(Z294)、(I-1)+(Z295)、(I-1)+(Z296)、(I-1)+(Z297)、(I-1)+(Z298)、(I-1)+(Z299)、(I-1)+(Z300)、(I-1)+(Z301)、(I-1)+(Z302)、(I-1)+(Z303)、(I-1)+(Z304)、(I-1)+(Z305)、(I-1)+(Z306)、(I-1)+(Z307)、(I-1)+(Z308), (I-1)+(Z309), (I-1)+(Z310), (I-1)+(Z311), (I-1)+(Z312), (I-1)+(Z313), (I-1)+(Z314), (I-1)+(Z315), (I-1)+(Z316), (I-1)+(Z317), (I-1)+(Z318), (I-1)+(Z319), (I-1)+(Z320), (I-1)+(Z321), (I-1)+(Z322), (I-1)+(Z323), (I-1)+(Z324), (I-1)+(Z325), (I-1)+(Z326), (I-1)+(Z327), (I-1)+(Z328), (I-1)+(Z329), (I-1)+(Z330), (I-1)+(Z331), (I-1)+(Z332), (I-1)+(Z333), (I-1)+(Z334), (I-1)+(Z335), (I-1)+(Z336), (I-1)+(Z337), (I-1)+(Z338), (I-1)+(Z339), (I-1)+(Z340), (I-1)+(Z341), (I-1)+(Z342), (I-1)+(Z343), (I-1)+(Z344), (I-1)+(Z345), (I-1)+(Z346), (I-1)+(Z347), (I-1)+(Z348), (I-1)+(Z349), (I-1)+(Z350), (I-1)+(Z351), (I-1)+(Z352), (I-1)+(Z353), (I-1)+(Z354), (I-1)+(Z355), (I-1)+(Z356), (I-1)+(Z357), (I-1)+(Z358), (I-1)+(Z359), (I-1)+(Z360), (I-1)+(Z361), (I-1)+(Z362), (I-1)+(Z363), (I-1)+(Z364), (I-1)+(Z365), (I-1)+(Z366), (I-1)+(Z367), (I-1)+(Z368), (I-1)+(Z369), (I-1)+(Z370), (I-1)+(Z371), (I-1)+(Z372), (I-1)+(Z373), (I-1)+(Z374), (I-1)+(Z375), (I-1)+(Z376) and (I-1)+(Z377).

[0076] Table 3: The combinations [(I-2)+(II-1A)~[(I-2)+(II-33)] or [(I-2)+(Z001)]~[(I-2)+(Z377)] are defined as the combinations [(I-1)+(II-1A)~[(I-1)+(II-33)] or [(I-1)+(Z001)]~[(I-1)+(Z386)] in Table 2, where compound (I-1) in each mixture is replaced by compound (I-2).

[0077] Table 4: The combination [(I-3)+(II-1A)~[(I-3)+(II-33)] or [(I-3)+(Z001)]~[(I-3)+(Z377)] is defined as the combination [(I-1)+(II-1A)~[(I-1)+(II-33)] or [(I-1)+(Z001)]~[(I-1)+(Z377)] in Table 2, where compound (I-1) in each mixture is replaced by compound (I-3).

[0078] Table 5: The combination [(I-4)+(II-1A)~[(I-4)+(II-33)] or [(I-4)+(Z001)]~[(I-4)+(Z377)] is defined as the combination [(I-1)+(II-1A)~[(I-1)+(II-33)] or [(I-1)+(Z001)]~[(I-1)+(Z377)] in Table 2, where compound (I-1) in each mixture is replaced by compound (I-4).

[0079] Table 6: The combination [(I-5)+(II-1A)~[(I-5)+(II-33)] or [(I-5)+(Z001)]~[(I-5)+(Z377)] is defined as the combination [(I-1)+(II-1A)~[(I-1)+(II-33)] or [(I-1)+(Z001)]~[(I-1)+(Z377)] in Table 2, where compound (I-1) in each mixture is replaced by compound (I-5).

[0080] Table 7: The combination [(I-6)+(II-1A)~[(I-6)+(II-33)] or [(I-6)+(Z001)]~[(I-6)+(Z377)] is defined as the combination [(I-1)+(II-1A)~[(I-1)+(II-33)] or [(I-1)+(Z001)]~[(I-1)+(Z377)] in Table 2, where compound (I-1) in each mixture is replaced by compound (I-6).

[0081] Table 8: The combination [(I-7)+(II-1A)~[(I-7)+(II-33)] or [(I-7)+(Z001)]~[(I-7)+(Z377)] is defined as the combination [(I-1)+(II-1A)~[(I-1)+(II-33)] or [(I-1)+(Z001)]~[(I-1)+(Z377)] in Table 2, where compound (I-1) in each mixture is replaced by compound (I-7).

[0082] Table 9: The combination [(I-8)+(II-1A)~[(I-8)+(II-33)] or [(I-8)+(Z001)]~[(I-8)+(Z377)] is defined as the combination [(I-1)+(II-1A)~[(I-1)+(II-33)] or [(I-1)+(Z001)]~[(I-1)+(Z377)] in Table 2, where compound (I-1) in each mixture is replaced by compound (I-8).

[0083] Table 10: The combination [(I-9)+(II-1A)~[(I-9)+(II-33)] or [(I-9)+(Z001)]~[(I-9)+(Z377)] is defined as the combination [(I-1)+(II-1A)~[(I-1)+(II-33)] or [(I-1)+(Z001)]~[(I-1)+(Z377)] in Table 2, where compound (I-1) in each mixture is replaced by compound (I-9).

[0084] Table 11: The combination [(I-10)+(II-1A)~[(I-10)+(II-33)] or [(I-10)+(Z001)]~[(I-10)+(Z377)] is defined as the combination [(I-1)+(II-1A)~[(I-1)+(II-33)] or [(I-1)+(Z001)]~[(I-1)+(Z377)] in Table 2, where compound (I-1) in each mixture is replaced by compound (I-10).

[0085] Table 12: The combination [(I-11)+(II-1A)~[(I-11)+(II-33)] or [(I-11)+(Z001)]~[(I-11)+(Z377)] is defined as the combination [(I-1)+(II-1A)~[(I-1)+(II-33)] or [(I-1)+(Z001)]~[(I-1)+(Z377)] in Table 2, where compound (I-1) in each mixture is replaced by compound (I-11).

[0086] Preferably, the combinations listed in Table 2 below, wherein component (1) is compound (I-1) and component (2) is selected from compounds (Z001) to (Z377) as defined herein.

[0087] (I-1) + Broflanilide (Z273), (I-1) + Bifenthrin (Z103), (I-1) + Emamectin benzoate (Z167), (I-1) + Indoxacarb (Z240), (I-1) + Fluxamethamide (Z274), (I-1) + Spinosad (Z165), (I-1) + Spinetoram (Z164), (I-1) + Imidaclopride (Z151), (I-1) + Thiamethoxam (Z154), (I-1) + Clothianidin (Z149), (I-1) + Afidopiropen (Z190), (I-1) + Triflumezopyrim (Z161), (I-1) + Bacillus thuringiensis (Z195), (I-1) + zinpropyridaz (Z317), (I-1) + ticlopyrazoflor (Z318), (I-1) + isocycloseram (Z275), (I-1) + flomethquin (Z292), (I-1) + fipronil (Z095), (I-1) + pyridaryl (Z299), (I-1) + oxazosulfyl (Z243), (I-1) + chlorfenapir (Z203), (I-1) + metaflumizone (Z241), (I-1) + pyriproxyfen (Z174), (I-1) + abamectin (Z166), (I-1) + pymetrozine (Z188).

[0088] The following combinations are listed in Table 13, wherein component (1) is a group represented by formula "(I)" including the compound of formula (I), compounds I-1, I-2, I-3, I-4, I-5, I-6, I-7, I-8, I-9, I-10, and I-11, and component (2) is selected from groups A) to P) as defined herein.

[0089] Table-13: (I)+(A001)、(I)+(A002)、(I)+(A003)、(I)+(A004)、(I)+(A005)、(I)+(A006)、(I)+(A007)、(I)+(A008)、(I)+(A009)、(I)+(A010)、(I)+(A011)、(I)+(A012)、(I)+(A013)、(I)+(A014)、(I)+(A015)、(I)+(A016)、(I)+(A017)、(I)+(A018)、(I)+(A019)、(I)+(A020)、(I)+(A021)、(I)+(A022)、(I)+(A023)、(I)+(A024)、(I)+(A025)、(I)+(A026)、(I)+(A027)、(I)+(A028)、(I)+(A029)、(I)+(A030)、(I)+(A031)、(I)+(A032)、(I)+(A033)、(I)+(A034)、(I)+(A035)、(I)+(A036)、(I)+(A037)、(I)+(A038)、(I)+(A039)、(I)+(A040)、(I)+(A041)、(I)+(A042)、(I)+(A043)、(I)+(A044)、(I)+(A045)、(I)+(A046)、(I)+(A047)、(I)+(A048)、(I)+(A049)、(I)+(A050)、(I)+(A051)、(I)+(A052)、(I)+(A053)、(I)+(A054)、(I)+(A055)、(I)+(A056)、(I)+(A057)、(I)+(A058)、(I)+(A059)、(I)+(A060)、(I)+(A061)、(I)+(A062)、(I)+(A063)、(I)+(A064)、(I)+(A065)、(I)+(A066)、(I)+(A067)、(I)+(A068)、(I)+(A069)、(I)+(A070)、(I)+(A071)、(I)+(A072)、(I)+(A073)、(I)+(A074)、(I)+(A075)、(I)+(A076)、(I)+(A077)、(I)+(A078)、(I)+(A079)、(I)+(A080)、(I)+(A081)、(I)+(A082)、(I)+(A083)、(I)+(A084)、(I)+(B001)、(I)+(B002)、(I)+(B003)、(I)+(B004)、(I)+(B005)、(I)+(B006)、(I)+(B007)、(I)+(B008)、(I)+(B009)、(I)+(B010)、(I)+(B011)、(I)+(B012)、(I)+(B013)、(I)+(B014)、(I)+(B015)、(I)+(B016)、(I)+(B017)、(I)+(B018)、(I)+(B019)、(I)+(B020)、(I)+(B021)、(I)+(B022)、(I)+(B023)、(I)+(B024)、(I)+(B025)、(I)+(B026)、(I)+(B027)、(I)+(B028)、(I)+(B029)、(I)+(B030)、(I)+(B031)、(I)+(B032)、(I)+(B033)、(I)+(B034)、(I)+(B035)、(I)+(B036)、(I)+(B037)、(I)+(B038)、(I)+(B039)、(I)+(B040)、(I)+(B041)、(I)+(B042)、(I)+(B043)、(I)+(B044)、(I)+(B045)、(I)+(B046)、(I)+(B047)、(I)+(B048)、(I)+(B049)、(I)+(B050)、(I)+(B051)、(I)+(B052)、(I)+(B053)、(I)+(B054)、(I)+(B055)、(I)+(B056)、(I)+(B057)、(I)+(B058)、(I)+(B059)、(I)+(B060)、(I)+(C001)、(I)+(C002)、(I)+(C003)、(I)+(C004)、(I)+(C005)、(I)+(C006)、(I)+(C007)、(I)+(C008)、(I)+(C009)、(I)+(C010)、(I)+(C011)、(I)+(C012)、(I)+(C013)、(I)+(C014)、(I)+(C015)、(I)+(C016)、(I)+(C017)、(I)+(C018)、(I)+(C019)、(I)+(C020)、(I)+(C021)、(I)+(C022)、(I)+(C023)、(I)+(C024)、(I)+(C025)、(I)+(C026)、(I)+(C027)、(I)+(C028)、(I)+(C029)、(I)+(C030)、(I)+(D001)、(I)+(D002)、(I)+(D003)、(I)+(D004)、(I)+(D005)、(I)+(D006)、(I)+(D007)、(I)+(D008)、(I)+(D009)、(I)+(D010)、(I)+(D011)、(I)+(D012)、(I)+(D013)、(I)+(D014)、(I)+(D015)、(I)+(D016)、(I)+(D017)、(I)+(D018)、(I)+(D019)、(I)+(D020)、(I)+(D021)、(I)+(D022)、(I)+(D023)、(I)+(D024)、(I)+(D025)、(I)+(E001)、(I)+(E002)、(I)+(E003)、(I)+(E004)、(I)+(E005)、(I)+(E006)、(I)+(E007)、(I)+(E008)、(I)+(E009)、(I)+(E010)、(I)+(E011)、(I)+(E012)、(I)+(E013)、(I)+(E014)、(I)+(E015)、(I)+(E016)、(I)+(E017)、(I)+(E018)、(I)+(E019)、(I)+(E020)、(I)+(E021)、(I)+(E022)、(I)+(E023)、(I)+(F001)、(I)+(F002)、(I)+(F003)、(I)+(F004)、(I)+(G001)、(I)+(G002)、(I)+(G003)、(I)+(G004)、(I)+(G005)、(I)+(G006)、(I)+(H001)、(I)+(I001)、(I)+(I002)、(I)+(I003)、(I)+(I004)、(I)+(I005)、(I)+(I006)、(I)+(I007)、(I)+(I008)、(I)+(I009)、(I)+(J001)、(I)+(J002)、(I)+(J003)、(I)+(K001)、(I)+(K002)、(I)+(L001)、(I)+(L002)、(I)+(L003)、(I)+(L004)、(I)+(M001)、(I)+(M002)、(I)+(M003)、(I)+(M004)、(I)+(M005)、(I)+(M006)、(I)+(N001)、(I)+(N002)、(I)+(O001)、(I)+(O002)、(I)+(O003)、(I)+(O004)、(I)+(O005)、(I)+(O006)、(I)+(O007)、(I)+(O008)、(I)+(O009)、(I)+(O010)、(I)+(O011)、(I)+(O012)、(I)+(O013)、(I)+(O014)、(I)+(O015)、(I)+(O016)、(I)+(O017)、(I)+(O018)、(I)+(O019)、(I)+(O020)、(I)+(O021)、(I)+(O022)、(I)+(O023)、(I)+(O024)、(I)+(O025)、(I)+(O026)、(I)+(O027)、(I)+(O028)、(I)+(O029)、(I)+(O030)、(I)+(O031)、(I)+(O032)、(I)+(O033)、(I)+(O034)、(I)+(O035)、(I)+(O036)、(I)+(O037)、(I)+(O038)、(I)+(O039)、(I)+(O040)、(I)+(O041)、(I)+(O042)、(I)+(O043)、(I)+(O044)、(I)+(O045)、(I)+(O046)、(I)+(O047)、(I)+(O048)、(I)+(O049)、(I)+(O050)、(I)+(O051)、(I)+(O052)、(I)+(O053)、(I)+(O054)、(I)+(O055)、(I)+(O056)、(I)+(O057)、(I)+(O058)、(I)+(O059)、(I)+(O060)、(I)+(O061)、(I)+(O062)、(I)+(O063)、(I)+(O064)、(I)+(O065)、(I)+(O066)(I)+(P001)、(I)+(P002)、(I)+(P003)、(I)+(P004)、(I)+(P005)、(I)+(P006)、(I)+(P007)、(I)+(P008)、(I)+(P009)、(I)+(P010)、(I)+(P011)、(I)+(P012)、(I)+(P013)、(I)+(P014)、(I)+(P015)、(I)+(P016)、(I)+(P017)、(I)+(P018)、(I)+(P019)、(I)+(P020)、(I)+(P021)、(I)+(P022)、(I)+(P023)、(I)+(P024)、(I)+(P025)、(I)+(P026)、(I)+(P027)、(I)+(P028)、(I)+(P029)、(I)+(P030)、(I)+(P031)、(I)+(P032)、(I)+(P033)、(I)+(P034)、(I)+(P035)、(I)+(P036)、(I)+(P037)、(I)+(P038)、(I)+(P039)、(I)+(P040), (I)+(P041), (I)+(P042), (I)+(P043), (I)+(P044), (I)+(P045), (I)+(P046), (I)+(P047), (I)+(P048), (I)+(P049), (I)+(P050), (I)+(P051), (I)+(P052), (I)+(P053), (I)+(P054), (I)+(P055), (I)+(P056), (I)+(P057), (I)+(P058), (I)+(P059), (I)+(P060), (I)+(P061), (I)+(P062), (I)+(P063), (I)+(P064), (I)+(P065), (I)+(P066), (I)+(P067), (I)+(P068), (I)+(P069), (I)+(P070), (I)+(P071), (I)+(P072), (I)+(P073), (I)+(P074), (I)+(P075), (I)+(P076), (I)+(P077), (I)+(P078), (I)+(P079), (I)+(P080), (I)+(P081), (I)+(P082), (I)+(P083), (I)+(P084), (I)+(P085), (I)+(P086), (I)+(P087), (I)+(P088), (I)+(P089), (I)+(P090), (I)+(P091), (I)+(P092), (I)+(P093), (I)+(P094), (I)+(P095), (I)+(P096), (I)+(P097), (I)+(P098), (I)+(P099), (I)+(P100), (I)+(P101), (I)+(P102), (I)+(P103). ,

[0090] In one embodiment, in the combinations [(I)+(A001)]~[(I)+(P103)] in Table 13, the weight ratio of component (1) to component (2) is between 500:1 and 1:500.

[0091] In one embodiment, in the combinations [(I)+(A001)]~[(I)+(P103)] in Table 13, the weight ratio of component (1) to component (2) is between 100:1 and 1:100.

[0092] In one embodiment, in the combinations [(I)+(A001)]~[(I)+(P103)] shown in Table 13, the weight ratio of component (1) to component (2) is between 50:1 and 1:50.

[0093] In one embodiment, in the combinations [(I)+(A001)]~[(I)+(P103)] shown in Table 13, the weight ratio of component (1) to component (2) is between 20:1 and 1:20.

[0094] In one embodiment, in the combinations [(I)+(A001)]~[(I)+(P103)] shown in Table 13, the weight ratio of component (1) to component (2) is between 5:1 and 1:5.

[0095] In one embodiment, in the combinations [(I)+(A001)]~[(I)+(P103)] shown in Table 13, the weight ratio of component (1) to component (2) is between 3:1 and 1:3.

[0096] In one embodiment, in the combinations [(I)+(A001)]~[(I)+(P103)] shown in Table 13, the weight ratio of component (1) to component (2) is between 2:1 and 1:2.

[0097] In one embodiment, in the combinations [(I)+(A001)]~[(I)+(P103)] shown in Table 13, the weight ratio of component (1) to component (2) is 1:1.

[0098] The following combinations are listed in Table-14, wherein component (1) is compound (I-1) and component (2) is selected from groups A) to P) as defined herein.

[0099] Table 14: (I-1)+(A001)、(I-1)+(A002)、(I-1)+(A003)、(I-1)+(A004)、(I-1)+(A005)、(I-1)+(A006)、(I-1)+(A007)、(I-1)+(A008)、(I-1)+(A009)、(I-1)+(A010)、(I-1)+(A011)、(I-1)+(A012)、(I-1)+(A013)、(I-1)+(A014)、(I-1)+(A015)、(I-1)+(A016)、(I-1)+(A017)、(I-1)+(A018)、(I-1)+(A019)、(I-1)+(A020)、(I-1)+(A021)、(I-1)+(A022)、(I-1)+(A023)、(I-1)+(A024)、(I-1)+(A025)、(I-1)+(A026)、(I-1)+(A027)、(I-1)+(A028)、(I-1)+(A029)、(I-1)+(A030)、(I-1)+(A031)、(I-1)+(A032)、(I-1)+(A033)、(I-1)+(A034)、(I-1)+(A035)、(I-1)+(A036)、(I-1)+(A037)、(I-1)+(A038)、(I-1)+(A039)、(I-1)+(A040)、(I-1)+(A041)、(I-1)+(A042)、(I-1)+(A043)、(I-1)+(A044)、(I-1)+(A045)、(I-1)+(A046)、(I-1)+(A047)、(I-1)+(A048)、(I-1)+(A049)、(I-1)+(A050)、(I-1)+(A051)、(I-1)+(A052)、(I-1)+(A053)、(I-1)+(A054)、(I-1)+(A055)、(I-1)+(A056)、(I-1)+(A057)、(I-1)+(A058)、(I-1)+(A059)、(I-1)+(A060)、(I-1)+(A061)、(I-1)+(A062)、(I-1)+(A063)、(I-1)+(A064)、(I-1)+(A065)、(I-1)+(A066)、(I-1)+(A067)、(I-1)+(A068)、(I-1)+(A069)、(I-1)+(A070)、(I-1)+(A071)、(I-1)+(A072)、(I-1)+(A073)、(I-1)+(A074)、(I-1)+(A075)、(I-1)+(A076)、(I-1)+(A077)、(I-1)+(A078)、(I-1)+(A079)、(I-1)+(A080)、(I-1)+(A081)、(I-1)+(A08 2)、(I-1)+(A083)、(I-1)+(A084)、(I-1)+(B001)、(I-1)+(B002)、(I-1)+(B 003)、(I-1)+(B004)、(I-1)+(B005)、(I-1)+(B006)、(I-1)+(B007)、(I-1) +(B008)、(I-1)+(B009)、(I-1)+(B010)、(I-1)+(B011)、(I-1)+(B012)、(I- 1)+(B013)、(I-1)+(B014)、(I-1)+(B015)、(I-1)+(B016)、(I-1)+(B017)、 (I-1)+(B018)、(I-1)+(B019)、(I-1)+(B020)、(I-1)+(B021)、(I-1)+(B022 )、(I-1)+(B023)、(I-1)+(B024)、(I-1)+(B025)、(I-1)+(B026)、(I-1)+(B 027)、(I-1)+(B028)、(I-1)+(B029)、(I-1)+(B030)、(I-1)+(B031)、(I-1)+ (B032)、(I-1)+(B033)、(I-1)+(B034)、(I-1)+(B035)、(I-1)+(B036)、(I-1)+(B037)、(I-1)+(B038)、(I-1)+(B039)、(I-1)+(B040)、(I-1)+(B041)、( I-1)+(B042)、(I-1)+(B043)、(I-1)+(B044)、(I-1)+(B045)、(I-1)+(B046 )、(I-1)+(B047)、(I-1)+(B048)、(I-1)+(B049)、(I-1)+(B050)、(I-1)+(B0 51)、(I-1)+(B052)、(I-1)+(B053)、(I-1)+(B054)、(I-1)+(B055)、(I-1)+ (B056)、(I-1)+(B057)、(I-1)+(B058)、(I-1)+(B059)、(I-1)+(B060)、(I-1 )+(C001)、(I-1)+(C002)、(I-1)+(C003)、(I-1)+(C004)、(I-1)+(C005)、(I -1)+(C006)、(I-1)+(C007)、(I-1)+(C008)、(I-1)+(C009)、(I-1)+(C010)、(I-1)+(C011)、(I-1)+(C012)、(I-1)+(C013)、(I-1)+(C014)、(I-1)+(C015)、(I-1)+(C016)、(I-1)+(C017)、(I-1)+(C018)、(I-1)+(C019)、(I-1)+(C020)、(I-1)+(C021)、(I-1)+(C022)、(I-1)+(C023)、(I-1)+(C024)、(I-1)+(C025)、(I-1)+(C026)、(I-1)+(C027)、(I-1)+(C028)、(I-1)+(C029)、(I-1)+(C030)、(I-1)+(D001)、(I-1)+(D002)、(I-1)+(D003)、(I-1)+(D004)、(I-1)+(D005)、(I-1)+(D006)、(I-1)+(D007)、(I-1)+(D008)、(I-1)+(D009)、(I-1)+(D010)、(I-1)+(D011)、(I-1)+(D012)、(I-1)+(D013)、(I-1)+(D014)、(I-1)+(D015)、(I-1)+(D016)、(I-1)+(D017)、(I-1)+(D018)、(I-1)+(D019)、(I-1)+(D020)、(I-1)+(D021)、(I-1)+(D022)、(I-1)+(D023)、(I-1)+(D024)、(I-1)+(D025)、(I-1)+(E001)、(I-1)+(E002)、(I-1)+(E003)、(I-1)+(E004)、(I-1)+(E005)、(I-1)+(E006)、(I-1)+(E007)、(I-1)+(E008)、(I-1)+(E009)、(I-1)+(E010)、(I-1)+(E011)、(I-1)+(E012)、(I-1)+(E013)、(I-1)+(E014)、(I-1)+(E015)、(I-1)+(E016)、(I-1)+(E017)、(I-1)+(E018)、(I-1)+(E019)、(I-1)+(E020)、(I-1)+(E021)、(I-1)+(E022)、(I-1)+(E023)、(I-1)+(F001)、(I-1)+(F002)、(I-1)+(F003)、(I-1)+(F004)、(I-1)+(G001)、(I-1)+(G002)、(I-1)+(G003)、(I-1)+(G004)、(I-1)+(G005)、(I-1)+(G006)、(I-1)+(H001)、(I-1)+(I001)、(I-1)+(I002)、(I-1)+(I003)、(I-1)+(I004)、(I-1)+(I005)、(I-1)+(I006)、(I-1)+(I007)、(I-1)+(I008)、(I-1)+(I009)、(I-1)+(J001)、(I-1)+(J002)、(I-1)+(J003)、(I-1)+(K001)、(I-1)+(K002)、(I-1)+(L001)、(I-1)+(L002)、(I-1)+(L003)、(I-1)+(L004)、(I-1)+(M001)、(I-1)+(M002)、(I-1)+(M003)、(I-1)+(M004)、(I-1)+(M005)、(I-1)+(M006)、(I-1)+(N001)、(I-1)+(N002)、(I-1)+(O001)、(I-1)+(O002)、(I-1)+(O003)、(I-1)+(O004)、(I-1)+(O005)、(I-1)+(O006)、(I-1)+(O007)、(I-1)+(O008)、(I-1)+(O009)、(I-1)+(O010)、(I-1)+(O011)、(I-1)+(O012)、(I-1)+(O013)、(I-1)+(O014)、(I-1)+(O015)、(I-1)+(O016)、(I-1)+(O017)、(I-1)+(O018)、(I-1)+(O019)、(I-1)+(O020)、(I-1)+(O021)、(I-1)+(O022)、(I-1)+(O023)、(I-1)+(O024)、(I-1)+(O025)、(I-1)+(O026)、(I-1)+(O027)、(I-1)+(O028)、(I-1)+(O029)、(I-1)+(O030)、(I-1)+(O031)、(I-1)+(O032)、(I-1)+(O033)、(I-1)+(O034)、(I-1)+(O035)、(I-1)+(O036)、(I-1)+(O037)、(I-1)+(O038)、(I-1)+(O039)、(I-1)+(O040)、(I-1)+(O041)、(I-1)+(O042)、(I-1)+(O043)、(I-1)+(O044)、(I-1)+(O045)、(I-1)+(O046)、(I-1)+(O047)、(I-1)+(O048)、(I-1)+(O049)、(I-1)+(O050)、(I-1)+(O051)、(I-1)+(O052)、(I-1)+(O053)、(I-1)+(O054)、(I-1)+(O055)、(I-1)+(O056)、(I-1)+(O057)、(I-1)+(O058)、(I-1)+(O059)、(I-1)+(O060)、(I-1)+(O061)、(I-1)+(O062)、(I-1)+(O063)、(I-1)+(O064)、(I-1)+(O065)、(I-1)+(O066)(I-1)+(P001)、(I-1)+(P002)、(I-1)+(P003)、(I-1)+(P004)、(I-1)+(P005)、(I-1)+(P006)、(I-1)+(P007)、(I-1)+(P008)、(I-1)+(P009)、(I-1)+(P010)、(I-1)+(P011)、(I-1)+(P012)、(I-1)+(P013)、(I-1)+(P014)、(I-1)+(P015)、(I-1)+(P016)、(I-1)+(P017)、(I-1)+(P018)、(I-1)+(P019)、(I-1)+(P020)、(I-1)+(P021)、(I-1)+(P022)、(I-1)+(P023)、(I-1)+(P024)、(I-1)+(P025)、(I-1)+(P026)、(I-1)+(P027)、(I-1)+(P028)、(I-1)+(P029)、(I-1)+(P030)、(I-1)+(P031)、(I-1)+(P032)、(I-1)+(P033)、(I-1)+(P034)、(I-1)+(P035)、(I-1)+(P036)、(I-1)+(P037)、(I-1)+(P038)、(I-1)+(P039)、(I-1)+(P040)、(I-1)+(P041)、(I-1)+(P042)、(I-1)+(P043)、(I-1)+(P044)、(I-1)+(P045)、(I-1)+(P046)、(I-1)+(P047)、(I-1)+(P048)、(I-1)+(P049)、(I-1)+(P050)、(I-1)+(P051)、(I-1)+(P052)、(I-1)+(P053)、(I-1)+(P054)、(I-1)+(P055)、(I-1)+(P056)、(I-1)+(P057)、(I-1)+(P058)、(I-1)+(P059)、(I-1)+(P060)、(I-1)+(P061), (I-1)+(P062), (I-1)+(P063), (I-1)+(P064), (I-1)+(P065), (I-1)+(P066), (I-1)+(P067), (I-1)+(P068), (I-1)+(P069), (I-1)+(P070), (I-1)+(P071), (I-1)+(P072), (I-1)+(P073), (I-1)+(P074), (I-1)+(P075), (I-1)+(P076), (I-1)+(P077), (I-1)+ (P078), (I-1)+(P079), (I-1)+(P080), (I-1)+(P081), (I-1)+(P082), (I-1)+(P083), (I-1)+(P084), (I-1)+(P085), (I-1)+(P086), (I-1)+(P087), (I-1)+(P088), (I-1)+(P089), (I-1)+(P090), (I-1)+(P091), (I-1)+(P092), (I-1)+(P093), (I-1)+(P094), (I-1)+ (P095), (I-1)+(P096), (I-1)+(P097), (I-1)+(P098), (I-1)+(P099), (I-1)+(P100), (I-1)+(P101), (I-1)+(P102), (I-1)+(P103).

[0100] Table 15: The combination [(I-2)+(A001)]~[(I-2)+(P103)] is defined as the combination [(I-1)+(A001)]~[(I-1)+(P103)] in Table 14, where compound (I-1) in each mixture is replaced by compound (I-2).

[0101] Table 16: The combination [(I-3)+(A001)]~[(I-3)+(P103)] is defined as the combination [(I-1)+(A001)]~[(I-1)+(P103)] in Table 14, where compound (I-1) in each mixture is replaced by compound (I-3).

[0102] Table 17: The combination [(I-4)+(A001)]~[(I-4)+(P103)] is defined as the combination [(I-1)+(A001)]~[(I-1)+(P103)] in Table 14, where compound (I-1) in each mixture is replaced by compound (I-4).

[0103] Table 18: The combination [(I-5)+(A001)]~[(I-5)+(P103)] is defined as the combination [(I-1)+(A001)]~[(I-1)+(P103)] in Table 14, where compound (I-1) in each mixture is replaced by compound (I-5).

[0104] Table 19: The combination [(I-6)+(A001)]~[(I-6)+(P103)] is defined as the combination [(I-1)+(A001)]~[(I-1)+(P103)] in Table 14, where compound (I-1) in each mixture is replaced by compound (I-6).

[0105] Table 20: The combination [(I-7)+(A001)]~[(I-7)+(P103)] is defined as the combination [(I-1)+(A001)]~[(I-1)+(P103)] in Table 14, where compound (I-1) in each mixture is replaced by compound (I-7).

[0106] Table 21: The combination [(I-8)+(A001)~[(I-7)+(P103)] is defined as the combination [(I-1)+(A001)~[(I-1)+(P103)] in Table 14, where compound (I-1) in each mixture is replaced by compound (I-8).

[0107] Table 22: The combination [(I-9)+(A001)]~[(I-9)+(P103)] is defined as the combination [(I-1)+(A001)]~[(I-1)+(P103)] in Table 14, where compound (I-1) in each mixture is replaced by compound (I-9).

[0108] Table 23: The combination [(I-10)+(A001)~[(I-10)+(P103)] is defined as the combination [(I-1)+(A001)~[(I-1)+(P103)] in Table 14, where compound (I-1) in each mixture is replaced by compound (I-10).

[0109] Table 24: The combination [(I-11)+(A001)]~[(I-11)+(P103)] is defined as the combination [(I-1)+(A001)]~[(I-1)+(P103)] in Table 14, where compound (I-1) in each mixture is replaced by compound (I-11).

[0110] The following combinations are listed in Table-14, wherein component (1) is compound (I-1) and component (2) is selected from groups A) to P) as defined herein.

[0111] (I-1)+(A001) cyproconazole, (I-1)+(A002) diphenconazole, (I-1)+(A004) tetraconazole, (I-1)+(A006) fenpropimorph, (I-1)+(A009) flutriafoll, (I-1)+(A013) metconazole, (I-1)+(A017) propiconazole, (I-1)+(A018) prothioconazole, (I-1)+(A021) tebuconazole Lu, (I-1)+(A022) Epoxyconazole, (I-1)+(A081) Mefentrifluconazole, (I-1)+(B001) Benzovindiflupir, (I-1)+(B002) Bixafen, (I-1)+(B005) Fluopyram, (I-1)+(B007) Fluxapiroxad, (I-1)+(B019) Pidiflumetofen, (I-1)+(B30) Fluindapir, (I-1)+(B038) Isoflu Cipram (isoflucpyram), (I-1) + (B059) Impilfluxam, (I-1) + (C003) Azoxystrobin, (I-1) + (C012) Fluoxastrobin, (I-1) + (C014) Metminostrobin, (I-1) + (C017) Pyraclostrobin, (I-1) + (C016) Picoxystrobin, (I-1) + (C020) Trifloxystrobin, (I-1) + (C025) (3 S,6S,7R,8R)-8-benzyl-3-[({3-[(isobutyryloxy)methoxy]-4-methoxypyridine-2-yl}carbonyl)amino]-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl-2-methylpropanoate (fenpicoxamide), (I-1)+(C030)1-(2-{[1-(4-chlorophenyl)pyrazole-3-yl]oxymethyl}3-methylphenyl)-1,4-Dihydro-4-methyl-5H-tetrazole-5-one (methyltetraprole), (I-1)+(D001)Carbendazim, (I-1)+(D007)Thiophanate-methyl, (I-1)+(E004)Chlorothalonyl, (I-1)+(E010)Dithianone, (I-1)+(E013)Mancozeb, (I-1)+(E020)Thyram, (I-1 )+(F002)Isothianil, (I-1)+(F003)Probenazole (L003)Metalaxyl, (I-1)+(M001)Fludioxonil, (I-1)+(N001)Fluazinum, (I-1)+(O022)Oxathiapiproline, (I-1)+(O043)2-{3-[2-(1-{[3,5-Bis(difluoromethyl)-1H-pyrazole [-1-yl]acetyl}piperidine-4-yl)-1,3-thiazole-4-yl]-4,5-dihydro-1,2-oxazole-5-yl}-3-chlorophenylmethanesulfonate (fluoxapiproline), (I-1)+(O046)3-(4,4,5-trifluoro-3,3-dimethyl-3,4-dihydroisoquinoline-1-yl)quinoline, (I-1)+(O047)3-(4,4-difluoro-3,3-dimethyl-3,4-dihydroisoquinoline-1-yl)quinoline (quinohumerine), (I-1)+(O065)ipfluphenoquine, and (I-1)+(P094)N-(2-fluorophenyl)-4-[5-(trifluoromethyl)-1,2,4-oxadiazole-3-yl]benzamide.

[0112] Preferably, component (1) is compound (I-1), and component (2) is selected from groups A) to P) as defined herein, as listed in Table-14 below.

[0113] (I-1)+(C003), (I-1)+(C017), (I-1)+(L003), (I-1)+(D007), (I-1)+(B007), (I-1)+(M001), (I-1)+(F003), (I-1)+(F002), (I-1)+(B005).

[0114] In another embodiment, the mixture according to the present invention is a mixture of one active compound of formula (I) and at least one active component (2).

[0115] In another embodiment, the mixture according to the present invention is a mixture of one active compound of formula (I) and two active components (2) as compound (II), or a mixture of two active components (2) as compound (III), or a mixture of one active component (2) as compound (II) and a further active component (2) selected, for example, from compound (III) described herein (a three-component mixture).

[0116] In another embodiment, the mixture according to the present invention is a mixture of one active compound of formula (I) and three active components (2), or a mixture of three active compounds selected from group compound (II) and compound (III) (here, at least one compound is selected from compound (II)) (a four-formula mixture).

[0117] Compounds of formula (I) can be obtained by various routes, similar to the processes and examples disclosed in WO2019150220.

[0118] The mixture according to the present invention is particularly suitable for efficiently controlling harmful arthropods, such as arachnids, myriapods, insects, and nematodes.

[0119] Insects, arachnids, and nematodes The mixture according to the present invention is particularly suitable for efficiently controlling the following pests: Agrotis spp.: Acronta major, Adoxophyes orana, Aedia leucomelas, Agrotis spp segetum、Agrotis ipsilon;Alabama argillacea、Anticarsia gemmatalis、Anticarsia spp.、Argyresthia conjugella、Autographa gamma、Barathra brassicae、Bucculatrix thurberiella、Bupalus piniarius、Cacoecia murinana、Cacoecia podana、Capua reticulana、Carpocapsa pomonella、Cheimatobia brumata、Chilo spp.、Chilo suppressalis; spp.. Cydia pomonella chrysorrhoea, Euxoa spp., Evetria bouliana, Feltia spp., Feltia subterranean; armigera、Helicoverpa zea;Heliothis spp., for example, Heliothis armigera, Heliothis virescens, Heliothis zea; Hellula undalis, Hibernia defoliaria, Hofmannophila pseudospretella, Homona magnanima, Hyphantria cunea, Hyponomeuta padella, Hyponomeuta malinellus, Keiferia lycopersicella, Lambdina fiscellaria, Laphygma spp., for example, Laphygma exigua; Leucoptera coffeella, Leucoptera scitella, Lithocolletis blancardella, Lithophane antennata, Lobesia botrana, Loxagrotis albicosta, Loxostege sticticalis, Lymantria spp., for example, Lymantria dispar, Lymantria monacha; Lyonetia clerkella, Malacosoma neustria, Mamestra spp., for example, Mamestra brassicae; Mocis repanda, Mythimna separata, Orgyia pseudotsugata, Oria spp., Ostrinia spp., for example, Ostrinia nubilalis; Oulema oryzae, Panolis flammea, Pectinophora spp., e.g., Pectinophora gossypiella; Peridroma saucia, Phalera bucephala, Phthorimaea spp., e.g., Phthorimaea operculella; Phyllocnistis citrella, Pieris spp., e.g., Pieris brassicae, Pieris rapae; Plathypena scabra, Plutella maculipennis, Plutella xylostella, Prodenia spp., Pseudaletia spp., Pseudoplusia includens, Pyrausta nubilalis, Rhyacionia frustrana, Scrobipalpula absoluta, Sitotroga cerealella, Sparganothis pilleriana, Spodoptera spp., e.g., Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura; Thaumatopoea pityocampa, Thermesia gemmatalis, Tinea pellionella, Tineola bisselliella, Tortrix viridana, Trichoplusia spp., e.g., Trichoplusia ni; Tuta absoluta, and Zeiraphera canadensis, beetles (Cerulea), e.g., Acanthoscehdes obtectus, Adoretus spp., Agelastica alni, Agrilus sinuatus, Agriotes spp., e.g., Agriotes fuscicollis, Agriotes lineatus, Agriotes obscurus; Amphimallus solstitialis, Anisandrus dispar, Anobium punctatum, Anomala rufocuprea, Anoplophora spp., e.g., Anoplophora glabripennis; Anthonomus spp., for example, Anthonomus grandis, Anthonomus pomorum; Anthrenus spp., Aphthona euphoridae, Apogonia spp., Athous haemorrhoidalis, Atomaria spp., for example, Atomaria linearis; Attagenus spp., Aulacophora femoralis, Blastophagus piniperda, Blitophaga undata, Bruchidius obtectus, Bruchus spp., for example, Bruchus lentis, Bruchus pisorum, Bruchus rufimanus; Byctiscus betulae, Callosobruchus chinensis, Cassida nebulosa, Cerotoma trifurcata, Cetonia aurata, Ceuthorhynchus spp., for example, Ceuthorhynchus assimilis, Ceuthorhynchus napi; Chaetocnema tibialis, Cleonus mendicus, Conoderus spp., for example, Conoderus vespertinus; Cosmopolites spp., Costelytra zealandica, Crioceris asparagi, Cryptorhynchus lapathi, Ctenicera ssp., for example, Ctenicera destructor; Curculio spp., Dectes texanus, Dermestes spp., Diabrotica spp., for example, Diabrotica 12-punctata Diabrotica speciosa, Diabrotica Iongicornis, Diabrotica semipunctata, Diabrotica virgifera; Epilachna spp., for example, Epilachna varivestis, Epilachna vigintioctomaculata; Epitrix spp., for example, Epitrix hirtipennis; Eutinobothrus brasiliensis, Faustinus cubae, Gibbium psylloides, Heteronychus arator, Hylamorpha elegans, Hylobius abietis, Hylotrupes bajulus, Hypera brunneipennis, Hypera postica, Hypothenemus spp., Ips typographus, Lachnosterna consanguinea, Lema bilineata, Lema melanopus, Leptinotarsa ​​spp., e.g., Leptinotarsa ​​decemlineata; Limoniuscalifornicus, Lissorhoptrus oryzophilus, Lissorhoptrus oryzophilus, Lixus spp., Lyctus spp., e.g., Lyctus bruneus; Melanotus communis, Meligethes spp., e.g., Meligethes aeneus; Melolontha hippocastani, Melolontha melolontha, Migdolus spp., Monochamus spp., e.g., Monochamus alternatus; Naupactus xanthographus, Niptus hololeucus, Oryctes rhinoceros, Oryzaephilus surinamensis, Otiorrhynchus sulcatus, Otiorrhynchus ovatus, Otiorrhynchus sulcatus, Oulema oryzae, Oxycetonia jucunda, Phaedon cochleariae, Phyllobius pyri, Phyllopertha horticola, Phyllophaga spp., Phyllotreta spp., e.g., Phyllotreta chrysocephala, Phyllotreta nemorum, Phyllotreta striolata; Phyllophaga spp., Phyllopertha horticola, Popillia japonica, Premnotrypes spp., Psylliodes chrysocephala, Ptinus spp., Rhizobius ventralis, Rhizopertha dominica, Sitona lineatus, Sitophilus spp., e.g., Sitophilus granaria, Sitophilus zeamais; Sphenophorus spp., e.g., Sphenophorus levis; Stemechus spp., e.g., Stemechus subsignatus; Symphyletes spp.Tenebrio molitor, Tribolium spp. (e.g., Tribolium castaneum; Trogoderma spp., Tychius spp., Xylotrechus spp., and Zabrus spp. (e.g., Zabrus tenebrioides), flies, mosquitoes (Diptera), (e.g., Aedes spp. (e.g., Aedes aegypti, Aedes albopictus, Aedes vexans; Anastrepha ludens), Anopheles spp. (e.g., Anopheles albimanus, Anopheles crucians, Anopheles freeb.) orni, Anopheles gambiae, Anopheles leucosphyrus, Anopheles maculipennis, Anopheles minimus, Anopheles quadrimaculatus, Anopheles sinensis; Bibio hortulanus, Calliphora erythrocephala, Calliphora vicina, Cerafitis capitata, Ceratitis capitata, Chrysomyia spp., e.g., Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria; Chrysops atlanticus, Chrysops discalis, Chrysops silacea, Cochliomyia spp., e.g., Cochliomyia hominivorax; Contarinia spp., e.g., Contarinia sorghicola; Cordylobia anthropophaga, Culex spp., e.g., Culex nigripalpus, Culex pipiens, Culex quinquefasciatus, Culex tarsalis, Culex tritaeniorhynchus; Culicoides furens, Culiseta inornata, Culiseta melanura, Cuterebra spp., Dacus cucurbitae, Dacus oleae, Dasineura brassicae, Delia spp., for example, Delia antique, Delia coarctata, Delia platura, Delia radicum; Dermatobia hominis, Drosophila spp., Fannia spp., for example, Fannia canicularis; Gastraphilus spp.For example, Gasterophilus intestinalis; Geomyza Tripunctata, Glossina fuscipes, Glossina morsitans, Glossina palpalis, Glossina tachinoides, Haematobia irritans, Haplodiplosis equestris, Hippelates spp., Hylemyia spp. spp., eg. spp., for example, Oscinella frit; Pegomya hysocyami, Phlebotomus argentipes, Phorbia spp., e.g., Phorbia antiqua, Phorbia brassicae, Phorbia coarctata; Prosimulium mixtum, Psila rosae, Psorophora columbiae, Psorophora discolor, Rhagoletis cerasi, Rhagoletis pomonella, Sarcophaga spp., e.g., Sarcophaga haemorrhoidalis; Simulium vittatum, Stomoxys spp., e.g., Stomoxys calcitrans; Tabanus spp., e.g., Tabanus atratus, Tabanus bovinus, Tabanus lineola, Tabanus similis; Tannia, spp., Tipula oleracea, Tipula paludosa, and Wohlfahrtia spp.; Thrips (Homoptera), e.g., Baliothrips biformis, Dichromothrips corbetti, Dichromothrips ssp., Enneothrips flavens, Frankliniella spp., e.g., Frankliniella fusca, Frankliniella occidentalis, Frankliniella tritici; Heliothrips spp., Hercinothrips femoralis, Kakothrips spp., Rhipiphorothrips cruentatus, Scirtothrips spp., e.g., Scirtothrips citri; Taeniothrips cardamoni; Thrips spp., e.g., Thrips oryzae, Thrips palmi, Thrips tabaci; Termites (Isoptera), e.g., Calotermes flavicollis, Coptotermes formosanus, Heterotermes aureus, Heterotermes Iongiceps, Heterotermes tenuis, Leucotermes flavipes, Odontotermes spp., Reticulitermes spp., e.g., Reticulitermes speratus, Reticulitermes flavipes, Reticulitermes grassei, Reticulitermes lucifugus, Reticulitermes santonensis, Reticulitermes virginicus; Termes natalensis, cockroaches (Cockroach order Blattodea), e.g., Acheta domesticus, Blatta orientalis, Blattella asahinae, Blattella germanica, Gryllotalpa spp., Leucophaea maderae, Locusta spp., Melanoplus spp., Periplaneta americana, Periplaneta australasiae, Periplaneta brunnea, Periplaneta fuligginosa, Periplaneta japonica, bugs, aphids, leafhoppers, scale insects, chafers, cicadas (Hemiptera), for example, Acrosternum spp., for example, Acrosternum hilare; Acyrthosipon spp., for example, Acyrthosiphon onobrychis, Acyrthosiphon pisum; Adelges laricis, Aeneolamia spp., Agonoscena spp., Aleurodes spp., Aleurolobus barodensis, Aleurothrixus spp., Amrasca spp., Anasa tristis, Antestiopsis spp., Anuraphis cardui, Aonidiella spp., Aphanostigma piri, Aphidula nasturtii, Aphis spp., for example, Aphis fabae, Aphis forbesi, Aphis gossypii, Aphis grossulariae, Aphis pomi, Aphis sambuci, Aphis schneideri, Aphis spiraecola; Arboridia apicalis, Arilus critatus, Aspidiella spp., Aspidiotus spp., Atanus spp., Aulacorthum solani, Bemisia spp., for example, Bemisia argentifolii, Bemisia tabaci; Blissus spp., for example, Blissus leucopterus; Brachycaudus cardui, Brachycaudus helichrysi, Brachycaudus persicae, Brachycaudus prunicola, Brachycolus spp., Brevicoryne brassicae, Calligypona marginata, Calocoris spp., Campylomma livida, Capitophorus horni, Carneocephala fulgida, Cavelerius spp., Ceraplastes spp., Ceratovacuna lanigera, Cercopidae, Cerosipha gossypii, Chaetosiphon fragaefolii, Chionaspis tegalensis, Chlorita onukii, Chromaphis juglandicola, Chrysomphalus ficus, Cicadulina mbila, Cimex spp., e.g., Cimex hemipterus, Cimex lectularius; Coccomytilus halli, Coccus spp., Creontiades dilutus, Cryptomyzus ribis, Cryptomyzus ribis, Cyrtopeltis notatus, Dalbulus spp., Dasynus piperis, Dialeurades spp., Diaphorina spp., Diaspis spp., Dichelops furcatus, Diconocoris hewetti, Doralis spp., Dreyfusia nordmannianae, Dreyfusia piceae, Drosicha spp., Dysaphis spp., e.g., Dysaphis plantaginea, Dysaphis pyri, Dysaphis radicola; Dysaulacorthum pseudosolani, Dysdercus spp., e.g., Dysdercus cingulatus, Dysdercus intermedius; Dysmicoccus spp., Empoasca spp., e.g., Empoasca fabae, Empoasca solana; Eriosoma spp., Erythroneura spp., Eurygaster spp., for example, Eurygaster integriceps; Euscelis bilobatus, Euschistus spp., for example, Euschistus heros, Euschistus impictiventris, Euschistus servus; Geococcus coffeae, Halyomorpha spp., for example, Halyomorpha halys; Heliopeltis spp., Homalodisca coagulata, Horcias nobilellus, Hyalopterus pruni, Hyperomyzus lactucae, Icerya spp., Idiocerus spp., Idioscopus spp., Laodelphax striatellus, Lecanium spp., Lepidosaphes spp., Lep. tocorisa spp., Leptoglossus phyllopus, Lipaphis erysimi, Lygus spp., e.g., Lygus hesperus, Lygus lineolaris, Lygus pratensis; Macropes excavatus, Macrosiphum spp., e.g., Macrosiphum rosae, Macrosiphum avenae, Macrosiphum euphorbiae; Mahanarva fimbriolata, Megacopta cribraria, Megoura viciae, Melanaphis pyrarius, Melanaphis sacchari, Metcafiella spp., Metopolophium dirhodum, Miridae spp., Monellia costalis, Monelliopsis pecanis, Myzus spp., e.g., Myzus ascalonicus, Myzus cerasi, Myzus persicae, Myzus varians; Nasonovia ribis-nigri, Nephotettix spp., e.g., Nephotettix malayanus, Nephotettix nigropictus, Nephotettix parvus, Nephotettix virescens; Nezara spp., e.g., Nezara viridula; Nilaparvata lugens, Oebalus spp., Oncometopia spp., Orthezia praelonga, Parabemisia myricae, Paratrioza spp., Parlatoria spp., Pemphigus spp., for example, Pemphigus bursarius; Pentomidae, Peregrinus maidis, Perkinsiella saccharicida, Phenacoccus spp., Phloeomyzus passerinii, Phorodon humuli, Phylloxera spp., Piesma quadrata, Piezodorus spp., e.g., Piezodorus guildinii, Pinnaspis aspidistrae, Planococcus spp., Protopulvinaria pyriformis, Psallus seriatus, Pseudacysta persea, Pseudaulacaspis pentagona, Pseudoococcus spp., e.g., Pseudoococcus comstocki; Psylla spp., e.g., Psylla mali, Psylla piri; Pteromalus spp., Pyrilla spp., Quadraspidiotus spp., Quesada gigas, Rastroccus spp., Reduvius senilis, Rhodnius spp., Rhopalomyzus ascalonicus, Rhopalosiphum spp., e.g., Rhopalosiphum pseudobrassicas, Rhopalosiphum insertum, Rhopalosiphum maidis, Rhopalosiphum padi; Sagatodes spp., Sahlbergella singularis, Saissetia spp., Sappaphis mala, Sappaphis mali, Scaphoides titanus, Schizaphis graminum, Schizoneura lanuginosa, Scotinophora spp., Selenaspidus articulatus, Sitobion avenae, Sogata spp., Sogatella furcifera, Solubea insularis, Stephanitis nashi, Stictocephala festina, Tenalaphara malayensis, Thyanta spp., e.g., Thyanta perditor; Tibraca spp., Tinocallis caryaefoliae, Tomaspis spp., Toxopteraspp., e.g., Toxoptera aurantii; Trialeurodes spp., e.g., Trialeurodes vaporariorum; Triatoma spp., Trioza spp., Typhlocyba spp., Unaspis spp., e.g., Unaspis yanonensis; and Viteus vitifolii, ants, wasps, hornets, wasps (Hymenoptera), e.g., Athalia rosae, Atta capiguara, Atta cephalotes, Atta cephalotes, Atta laevigata, Atta robusta, Atta sexdens, Atta texana, Bombus spp., Camponotus floridanus, Crematogaster spp., Dasymutilla occidentalis, Diprion spp., Dolichovespula maculata, Hoplocampa spp., e.g., Hoplocampa minuta, Hoplocampa testudinea; Lasius spp., e.g., Lasius niger, Linepithema humile, Monomorium pharaonis, Paravespula germanica, Paravespula pennsylvanica, Paravespula vulgaris, Pheidole megacephala, Pogonomyrmex barbatus, Pogonomyrmex californicus, Polistes rubiginosa, Solenopsis geminata, Solenopsis invicta, Solenopsis richteri、Solenopsis xyloni、Vespa spp., e.g. Vespa crabro, and Vespulasquamosa, crickets, grasshoppers, locusts (Orthoptera), e.g. Acheta domestica, Calliptamus italicus, Chortoicetes terminifera, Dociostaurus maroccanus, Gryllotalpa africana, Gryllotalpa gryllotalpa, Hieroglyphus daganensis, Kraussaria angulifera, Locusta migratoria, Locustana pardalina, Melanoplus bivittatus, Melanoplus femurrubrum, Melanoplus mexicanus, Melanoplus sanguinipes, Melanoplus spretus, Nomadacris septemfasciata, Oedaleus senegalensis, Schistocerca americana, Schistocerca gregaria, Tachycines asynamorus, and Zonozerus Variegatus, Arachnidae (class Arachnida), for example, dust mites, for example, those of the families Ixodes, Ixodes, and Sarcoptes, for example, Amblyomma spp. (e.g., Amblyomma americanum, Amblyomma variegatum, Amblyomma maculatum), Argas spp. (e.g., Argas persicus), Boophilus spp. (e.g., Boophilus annulatus, Boophilus decoloratus, Boophilus microplus), Dermacentor silvarum, Dermacentor andersoni, Dermacentor variabilis, Hyalomma spp. (e.g., Hyalomma truncatum), Ixodes spp. (e.g., Ixodes ricinus, Ixodes rubicundus, Ixodes scapularis, Ixodes holocyclus, Ixodes pacificus), Ornithodorus spp.(for example, Ornithodorus moubata, Ornithodorus hermsi, Ornithodorus turicata), Ornithonyssus bacoti, Otobius megnini, Dermanyssus gallinae, Psoroptes spp. (for example, Psoroptes ovis), Rhipicephalus spp. scabiei)、and Eriophyidae spp. eg Acaria sheldoni、Aculops spp. spp.; Tenuipalpidae spp., for example, Brevipalpus spp. (e.g., Brevipalpus phoenicis); Tetranychidae spp., e.g., Eotetranychus spp., Eutetranychus spp., Oligonychus spp., Tetranychus cinnabarinus, Tetranychus kanzawai, Tetranychus pacificus, Tetranychus telarius and Tetranychus urticae; Bryobia praetiosa, Panonychus spp. (e.g., Panonychus ulmi, Panonychus citri), Metatetranychus spp. and Oligonychus spp.(e.g., Oligonychus pratensis), Vasates lycopersici; Araneida, e.g., Latrodectus mactans, and Loxosceles reclusa, and Acarus siro, Chorioptes spp., Scorpio maurus, fleas (Cryptoptera), e.g., Ceratophyllus spp., Ctenocephalides felis, Ctenocephalides canis, Xenopsylla cheopis, Pulex irritans, Tunga penetrans, and Nosopsyllus fasciatus, silverfish, spotted silverfish (Lepisma), e.g., Lepisma saccharina and Thermobia domestica, centipedes (Chirolopoda), e.g., Geophilus spp., Scutigera spp., e.g., Scutigera coleoptrata; millipedes (Diplopoda), e.g., Blaniulus guttulatus, Narceus. spp., earwigs (Dermeptoptera), e.g., forficula auricularia; lice (Lyciformes), e.g., Damalinia spp., Pediculus spp., e.g., Pediculus humanus capitis, Pediculus humanus corporis; Pthirus pubis; Haematopinus spp., e.g., Haematopinus eurysternus, Haematopinus suis; Linognathus spp., e.g., Linognathus vituli; Bovicola bovis, Menopon gallinae, Menacanthus stramineus and Solenopotes capillatus; Trichodectes spp., springtails (Collimera), e.g., Onychiurus ssp., e.g., Onychiurus armatus.

[0120] The mixture according to the present invention is also suitable for the efficient control of nematodes: plant parasitic nematodes, e.g., root-knot nematodes, Meloidogyne hapla, Meloidogyne incognita, Meloidogyne javanica, and other Meloidogyne species; cyst-forming nematodes, Globodera rostochiensis and other Globodera species; Heterodera avenae, Heterodera glycines, Heterodera schachtii, Heterodera trifolii, and other Heterodera species; seed gall nematodes, Anguina species; honey nematodes, Aphelenchoides species, e.g., Aphelenchoides besseyi; bristly nematodes, Belonolaimus longicaudatus and other Belonolaimus species; pine nematodes, Bursaphelenchus lignicolus Mamiya et Kiyohara, Bursaphelenchus xylophilus and other Bursaphelenchus species; ring nematodes, Criconema species, Criconemella species, Criconemoides species, Mesocriconema species; stem and ring nematodes, Ditylenchus destructor, Ditylenchus dipsaci and other Ditylenchus species; cone nematodes, Dolichodorus species; spiral nematodes, Heliocotylenchus multicinctus and other Helicotylenchus species; sheath nematodes and sheath nematodes, Hemicycliophora species and Hemicriconemoides species; Hirshmanniella species; spear nematodes, Hoploaimus species; pseudorhizon-noduled nematodes, Nacobbus species; porcupine nematodes, Longidorus elongatus and other Longidorus species;Root-knot nematodes, Pratylenchus brachyurus, Pratylenchus neglectus, Pratylenchus penetrans, Pratylenchus curvitatus, Pratylenchus goodeyi and other Pratylenchus species; root-glue nematodes, Radopholus similis and other Radopholus species; false sedge nematodes, Rotylenchus robustus, Rotylenchus reniformis and other Rotylenchus species; Scutellonema species; ridge nematodes, Trichodorus primitivus and other Trichodorus species, Paratrichodorus species; sedge nematodes, Tylenchorhynchus claytoni, Tylenchorhynchus dubius and other Tylenchorhynchus species; citrus nematodes, Tylenchulus species, e.g., Tylenchulus semipenetrans; the large nematode, Xipinema species; and other plant parasitic nematode species.

[0121] Further examples of pests that can be controlled by the pest-killing mixture of the present invention include: dipoda, e.g., those of the class Dreissena; gastropods, e.g., Arion spp., Biomphalaria spp., Bulinus spp., Deroceras spp., Galba spp., Lymnaea spp., Oncomelania spp., Succinea spp.; parasitic worms, e.g., Ancylostoma duodenale, Ancylostoma ceylanicum, Acylostoma braziliensis, Ancylostoma spp., Ascaris lumbricoides, Ascaris spp., Brugia malayi, Brugia timori, unostomum spp., Chabertia spp., Clonorchis spp., Cooperia spp., Dicrocoelium spp., Dictyocaulus filaria, Diphyllobothrium latum, Dracunculus medinensis, Echinococcus granulosus, Echinococcus multilocularis, Enterobius vermicularis, Faciola spp., Haemonchus spp. For example, Haemonchus contortus; Heterakis spp., Hymenolepis nana, Hyostrongulus spp., Loa Loa, Nematodirus spp., Oesophagostomum spp., Opisthorchis spp., Onchocerca volvulus, Ostertagia spp., Paragonimus spp., Schistosomen spp., Strongyloides fuelleborni, Strongyloides stercora lis, Stronyloides spp.Taenia saginata, Taenia solium, Trichinella spiralis, Trichinella nativa, Trichinella britovi, Trichinella nelsoni, Trichinella pseudopsiralis, Trichostrongulus spp., Trichuris trichiura, Wuchereria bancrofti; those of the order Isopoda, e.g., Armadillidium vulgare, Oniscus asellus, Porcellio scaber; and those of the order Centipedes, e.g., Scutigerella immaculata.

[0122] The snowflakes are smooth and smooth with a smooth surface Some of these are: Anisoplia austriaca, Apamea spp., Austroasca viridigrisea, Baliothrips biformis, Caenorhabditis elegans, Cephus spp., Ceutorhynchus cucumber, Chaetocnema aridula, Chilo auricilius, Chilo indicus, Chilo polychrysus reticulatum 、Diatrea saccharalis 、Dichelops furcatus 、Dicladispa armigera 、Diloboderus spp sulfureus、Gryllotalpidae、Halotydeus destructor、Hypnodes bicolor、Hydrellia philippina、Julus spp.、Laodelphax spp.、Leptocorsia acuta、Leptocorsia oratorius、Leogenys fuscus、Lucillia spp fuscus., Mythemina separata, Neocapritermes opacus, Neocapritermes parvus, Neomegalotomus spp., Neotermes spp., Nymphula depunctalis, Oebalus pugnax, Orseolia spp. e.g., Orseolia oryzae; Oxycaraenus hyalinipennis, Plusia spp., Pomacea canaliculata, Procornitermes ssp., Procornitermes triacifer, Psylloides spp., Rachiplusia spp., Rhodopholus spp., Scaptocoris castanea, Scaptocoris spp., Scirpophaga spp. e.g., Scirpophaga incertulas, Scirpophaga innotata; Scotinophara spp. e.g., Scotinophara coarctata; Sesamia spp. e.g., Sesamia inferens, Sogaella frucifera, Solenapsis geminata, Spissistilus spp., Stalk borer, Stenchaetothrips biformis, Steneotarsonemus spinki, Sylepta derogata, Telehin licus, and Trichostrongylus spp.

[0123] The mixture of the present invention is particularly useful for controlling insects, preferably sap-sucking or burrowing insects, such as insects of the genera Thysanoptera, Diptera, and Hemiptera, as well as chewing-biting pests, such as insects of the genera Lepidoptera and Coleoptera, and is particularly useful for controlling the following species: Thysanoptera: Frankliniella fusca, Frankliniella occidentalis, Frankliniella tritici, Scirtothrips citri, Thrips oryzae, Thrips palmi, and Thrips tabaci; Diptera, such as Aedes aegypti, Aedes albopictus, Aedes vexans, Anastrepha ludens, Anopheles maculipennis, Anopheles crucians, Anopheles albimanus, Anopheles gambiae, Anopheles freeborni, Anopheles leucosphyrus, Anopheles minimus, Anopheles quadrimaculatus, Calliphora vicina, Ceratitis capitata, Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria, Chrysops discalis, Chrysops silacea, Chrysops atlanticus, Cochliomyia hominivorax, Contarinia sorghicola, Cordylobia Culicoides furens, Culex pipiens, Culex nigripalpus, Culex quinquefasciatus, Culex tarsalis, Culiseta inornata, Culiseta melanura, Dacus cucurbitae, Dacus oleae, Dasineura brassicae, Delia antique, Delia coarctata, Delia platura, Delia radicum, Dermatobia hominis, Fanniacanicularis, Geomyza Tripunctata, Gasterophilus intestinalis, Glossina morsitans, Glossina palpalis, Glossina fuscipes, Glossina tachinoides, Haematobia irritans, Haplodiplosis equestris, Hippelates spp., Hylemyia platura, Hypoderma lineata, Leptoconops torrens, Liriomyza sativae, Liriomyza trifolii, Lucilia caprina, Lucilia cuprina, Lucilia sericata, Lycoria pectoralis, Mansonia titillanus, Mayetiola destructor, Musca autumnalis, Musca domestica, Muscina stabulans, Oestrus ovis, Opomyza florum, Oscinella frit, Pegomya hysocyami, Phorbia antiqua, Phorbia brassicae, Phorbia coarctata, Phlebotomus argentipes, Psorophora columbiae, Psila rosae, Psorophora discolor, Prosimulium mixtum, Rhagoletis cerasi, Rhagoletis pomonella, Sarcophaga haemorrhoidalis, Sarcophaga spp., Simulium vittatum, Stomoxys calcitrans, Tabanus bovinus, Tabanus atratus, Tabanus lineola, and Tabanus similis, Tipula oleracea, and Tipula paludosa; Hemiptera, especially aphids: Acyrthosiphon onobrychis, Adelges laricis, Aphidula nasturtii, Aphis fabae, Aphis forbesi, Aphis pomi, Aphisgossypii, Aphis grossulariae, Aphis schneideri, Aphis spiraecola, Aphis sambuci, Acyrthosiphon pisum, Aulacorthum solani, Brachycaudus cardui, Brachycaudus helichrysi, Brachycaudus persicae, Brachycaudus prunicola, Brevicoryne brassicae, Capitophorus horni, Cerosipha gossypii, Chaetosiphon fragaefolii, Cryptomyzus ribis, Dreyfusia nordmannianae, Dreyfusia piceae, Dysaphis radicola, Dysaulacorthum pseudosolani, Dysaphis plantaginea, Dysaphis pyri, Empoasca fabae, Hyalopterus pruni, Hyperomyzus lactucae, Macrosiphum avenae, Macrosiphum euphorbiae, Macrosiphum rosae, Megoura viciae, Melanaphis pyrarius, Metopolophium dirhodum, Myzodes persicae, Myzus ascalonicus, Myzus cerasi, Myzus varians, Nasonovia ribis-nigri, Nilaparvata lugens, Pemphigus bursarius, Perkinsiella saccharicida, Phorodon humuli, Psylla mali, Psylla piri, Rhopalomyzus ascalonicus, Rhopalosiphum maidis, Rhopalosiphum padi, Rhopalosiphum insertum, Sappaphis mala, Sappaphis mali, Schizaphis graminum, Schizoneura lanuginosa, Sitobion avenae, Trialeurodesvaporariorum, Toxoptera aurantiiand, and Viteus vitifolii.

[0124] Lepidoptera, especially: Agrotis ipsilon, Agrotis segetum, Alabama argillacea, Anticarsia gemmatalis, Argyresthia conjugella, Autographa gamma, Bupalus piniarius, Cacoecia murinana, Capua reticulana, Cheimatobia brumata, Choristoneura fumiferana, Choristoneura occidentalis, Cirphis unipuncta, Cydia pomonella, Dendrolimus pini, Diaphania nitidalis, Diatraea grandiosella, Earias insulana, Elasmopalpus lignosellus, Eupoecilia ambiguella, Evetria bouliana, Feltia subterranea, Galleria mellonella, Grapholitha funebrana, Grapholitha molesta, Heliothis armigera, Heliothis virescens, Heliothis zea, Hellula undalis, Hibernia defoliaria, Hyphantria cunea, Hypononomeuta malinellus, Keiferia lycopersicella, Lambdina fiscellaria, Laphygma exigua, Leucoptera coffeella, Leucoptera scitella, Lithocolletis blancardella, Lobesia botrana, Loxostege sticticalis, Lymantria dispar, Lymantria monacha, Lyonetia clerkella, Malacosoma neustria, Mamestra brassicae, Orgyia pseudotsugata, Ostrinia nubilalis, Panolis flammea, Pectinophora gossypiella, Peridroma saucia, Phalerabucephala, Phthorimaea operculella, Phyllocnistis citrella, Pieris brassicae, Plathypena scabra, Plutella xylostella, Pseudoplusia includens, Rhyacionia frustrana, Scrobipalpula absoluta, Sitotroga cerealella, Sparganothis pilleriana, Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Thaumatopoea pityocampa, Tortrix viridana, Trichoplusia ni and Zeiraphera canadensis.

[0125] The mixture of the invention is particularly suitable for insects of the order Lepidoptera, in particular, Agrilus sinuatus, Agriotes lineatus, Agriotes obscurus, Amphimallus solstitialis, Anisandrus dispar, Anthonomus grandis, Anthonomus pomorum, Aphthona euphoridae, Athous haemorrhoidalis, Atomaria linearis, Blastophagus piniperda, Blitophaga undata, Bruchus rufimanus, Bruchus pisorum, Bruchus lentis, Byctiscus betulae, Cassida nebulosa, Cerotoma trifurcata, Cetonia aurata, Ceuthorrhynchus assimilis, Ceuthorrhynchus napi, Chaetocnema tibialis, Conoderus vespertinus, Crioceris asparagi, Ctenicera ssp., Diabrotica longicornis, Diabrotica semipunctata, Diabrotica 12-punctata Diabrotica speciosa, Diabrotica virgifera, Epilachna varivestis, Epitrix hirtipennis, Eutinobothrus brasiliensis, Hylobius abietis, Hypera brunneipennis, Hypera postica, Ips typographus, Lema bilineata, Lema melanopus, Leptinotarsa ​​decemlineata, Limonius californicus, Lissorhoptrus oryzophilus, Melanotus communis, Meligethes aeneus, Melolontha hippocastani, Melolontha melolontha, Oulema oryzae, Otiorrhynchus sulcatus, Otiorrhynchus ovatus, Phaedon cochleariae, Phyllobius pyri, Phyllotreta It is useful for controlling Chrysocephala, Phyllophaga sp., Phyllopertha horticola, Phyllotreta nemorum, Phyllotreta striolata, Popillia japonica, Sitona lineatus, and Sitophilus granaria.

[0126] The mixture of the present invention is particularly useful for controlling insects of the orders Lepidoptera, Coleoptera, Hemiptera, and Thymoptera.

[0127] The mixture of the present invention is particularly suitable for efficiently controlling pests such as lepidoptera (butterflies and moths), beetles (coleoptera), flies and mosquitoes (diptera), thrips (threptoptera), termites (isoptera), bugs, aphids, leafhoppers, whiteflies, scale insects, cicadas (hemiptera), ants, bees, wasps, sawflies (hymenoptera), crickets, grasshoppers, locusts (orthoptera), and even arachnids, such as insects of the order Arachnida (acari).

[0128] The term "mixture," as used herein, includes combinations.

[0129] The present invention also provides a method for controlling insects, mites, nematodes, or plant pathogenic fungi, comprising contacting the insects, mites, nematodes, or plant pathogenic fungi or their food sources, habitats, breeding sites, or habitats with an effective amount of the present invention that is effective in killing pests.

[0130] Furthermore, the present invention also relates to a method for protecting a plant from attack or parasitism by insects, mites, nematodes, or plant pathogenic fungi, which comprises contacting the plant, or the soil or water in which the plant is growing, with an effective amount of the present invention that is effective in killing pests.

[0131] The present invention also provides a method for protecting plant propagation material, preferably seeds, from soil insects, and seedlings, roots, and shoots from soil and leaf insects or fungi, the method comprising contacting plant propagation material, for example, seeds before sowing and / or after pre-germination treatment, with an effective amount of the mixture of the present invention that is effective in killing pests.

[0132] The present invention also provides seeds containing the mixture of the present invention.

[0133] The present invention also provides pest control compositions comprising a liquid or solid carrier and the pest-killing active mixture of the present invention.

[0134] The present invention also relates to the use of a pesticide mixture for controlling insects, mites, nematodes, or plant pathogenic fungi.

[0135] A mixture of the compound of formula (I) with at least one active compound (II) or at least one active compound (III) is referred to herein as "a mixture according to the present invention."

[0136] In certain embodiments, the mixture according to the present invention is a mixture (a two-component mixture) of one active compound of formula (I) and another active compound (II).

[0137] In certain embodiments, the mixture according to the present invention is a mixture (a two-component mixture) of one active compound of formula (I) and another active compound (III).

[0138] plant pathogenic fungi Non-limiting examples of fungal disease pathogens that can be treated according to the present invention include the following: The following powdery mildew pathogens cause diseases such as Blumeria species (e.g., Blumeria graminis); Podosphaera species (e.g., Podosphaera leucotricha); Sphaerotheca species (e.g., Sphaerotheca fuliginea); Uncinula species (e.g., Uncinulanecator); and Erysiphe species (e.g., Erysiphe cichoracearu). Diseases caused by the following rust pathogens, e.g., Gymnosporangium species, e.g., Gymnosporangium sabinae; Hemileia species, e.g., Hemileia vastatrix; Phakopsora species, e.g., Phakopsora pachyrhizi or Phakopsora meibomiae; Puccinia species, e.g., Puccinia recondita, Puccinia graminis or Puccinia striiformis and Puccinia melanocephala; Uromyces species, e.g., Uromyces appendiculatus; In particular, Cronatium ribicola (Pinus sieboldii rust); Gymnosporangium juniperi-virginianae (Cedar-apple rust); Hemileia vastatrix (Coffee rust); Phakopsora meibomiae and P. pachyrhizi (Soybean rust); Puccinia coronata (Oat and ryegrass crown rust); Puccinia graminis (Wheat and Kentucky bluegrass black rust, or grain black rust); Puccinia hemerocallidis (Licorice rust); Puccinia persistens subsp. triticina (Wheat rust or "brown or red rust"); Puccinia sorghi (Corn rust); Puccinia striiformis (Corn "yellow rust"); Puccinia melanocephala; Uromyces appendiculatus (Bean rust); Uromyces phaseoli (Bean rust); Puccinia Melanocephala (the "brown rust" disease of sugarcane); Puccinia kuehnii (the "orange rust" disease of sugarcane). Diseases caused by pathogens derived from the following groups of oomycetes, e.g., Albugo species, e.g., Albugo candida; Bremia species, e.g., Bremia lactucae; Peronospora species, e.g., Peronospora pisi or P. brassicae; Phytophthora species, e.g., Phytophthora infestans; Plasmopara species, e.g., Plasmopara viticola; Pseudoperonospora species, e.g., Pseudoperonospora humuli or Pseudoperonospora cubensis; Pythium species, e.g., Pythium ultimum; Leaf blight and leaf blight caused by the following: for example, Alternaria species, e.g., Alternaria solani; Cercospora species, e.g., Cercospora beticola; Cladiosporium species, e.g., Cladiosporium cucumerinum; Cochliobolus species, e.g., Cochliobolus sativus (conidial form: drexrella, syn: helmintosporium) or Cochliobolus miyabeanus; Colletotrichum species, e.g., Colletotrichum lindemuthanium; Cycloconium species, e.g., Cycloconium oleaginum; Diaporthe species, e.g., Diaporthe citri; Elsinoe species, e.g., Elsinoe fawcettii; Gloeosporium species, e.g., Gloeosporium laeticolor; Glomerella species, e.g., Glomerella cingulata; Guignardia species, e.g., Guignardia bidwelli; Leptosphaeria species, e.g., Leptosphaeria maculans; Magnaporthe species, e.g., Magnaporthe grisea; Microdochium species, e.g., Microdochium nivale; Mycosphaerella species, e.g., Mycosphaerella graminicola, Mycosphaerella arachidicola, or Mycosphaerella fijiensis; Phaeosphaeria species, e.g., Phaeosphaeria nodorum; Pyrenophora species, e.g., Pyrenophora teres, or Pyrenophora tritici repentis; Ramularia species, e.g., Ramularia collocygni, or Ramularia areola; Rhynchosporium species, e.g., Rhynchosporium secalis; Septoria species, e.g., Septoria apii, or Septoria lycopersici;Stagonospora species, e.g., Stagonospora nodorum; Typhula species, e.g., Typhula incarnata; Venturia species, e.g., Venturia inaequalis; Root and stem diseases caused by the following: for example, Corticium species, e.g., Corticium graminearum; Fusarium species, e.g., Fusarium oxysporum; Gaeumannomyces species, e.g., Gaeumannomyces graminis; Plasmodiophora species, e.g., Plasmodiophora brassicae; Rhizoctonia species, e.g., Rhizoctonia solani; Sarocladium species, e.g., Sarocladium oryzae; Sclerotium species, e.g., Sclerotium oryzae; Tapesia species, e.g., Tapesia acuformis; Thielaviopsis species, e.g., Thielaviopsis basicola; Ganoderma species, e.g., Ganoderma lucidum; Diseases of the ear and young ear (including the corn cob) caused by the following: for example, Alternaria species, e.g., Alternaria spp.; Aspergillus species, e.g., Aspergillus flavus; Cladosporium species, e.g., Cladosporium cladosporioides; Claviceps species, e.g., Claviceps purpurea; Fusarium species, e.g., Fusarium culmorum; Gibberella species, e.g., Gibberella zeae; Monographella species, e.g., Monographella nivalis; Stagnospora species, e.g., Stagnospora nodorum; Diseases caused by the following sooty mold fungi, e.g., Sphacelotheca species, e.g., Sphacelotheca reiliana; Tilletia species, e.g., Tilletia caries or Tilletia controversa; Urocystis species, e.g., Urocystis occulta; Ustilago species, e.g., Ustilago nuda; Fruit rot caused by the following: for example, Aspergillus species, e.g., Aspergillus flavus; Botrytis species, e.g., Botrytis cinerea; Penicillium species, e.g., Penicillium expansum or Penicillium purpurogenum; Rhizopus species, e.g., Rhizopus stolonifer; Sclerotinia species, e.g., Sclerotinia sclerotiorum; Verticilium species, e.g., Verticilium alboatrum; Seed and soil-borne rot and damping-off diseases, as well as seedling diseases, caused by the following species, e.g., Alternaria species, e.g., Alternaria brassicicola; Aphanomyces species, e.g., Aphanomyces euteiches; Ascochyta species, e.g., Ascochyta lentis; Aspergillus species, e.g., Aspergillus flavus; Cladosporium species, e.g., Cladosporium herbarum; Cochliobolus species, e.g., Cochliobolus sativus (conidial form: drexrella, vipolaris Syn: herminthosporium); Colletotrichum species, e.g., Colletotrichum coccodes; Fusarium species, e.g., Fusarium culmorum; Gibberella species, e.g., Gibberella zeae; Macrophonina species, e.g., Macrophonina phaseolina; Microdochium species, e.g., Microdochium nivale; Monographella species, e.g., Monographella nivalis; Penicillium species, e.g., Penicillium expansum; Phoma species, e.g., Phoma lingam; Phopsis species, e.g., Phopsis sojae; Phytophthora species, e.g., Phytophthora cactorum; Pyrenophora species, e.g., Pyrenophora graminea; Pyricularia species, e.g., Pyricularia oryzae; Pythium species, e.g., Pythium ultimum; Rhizoctonia species, e.g., Rhizoctonia solani; Rhizopus species, e.g., Rhizopus oryzae; Sclerotium species, e.g., Sclerotium rolfsii; Septoria species, e.g., Septoria nodorum; Typhula species, e.g., Typhula incarnata; Verticillium species, e.g., Verticillium dahliae; Cancers, bile duct and witches' broom diseases caused by the following, for example, Nectria species, for example, Nectria galligena; Damping-off diseases caused by the following, for example, Monilinia species, for example, Monilinia laxa; Deformations of leaves, flowers, and fruits caused by the following: for example, in the species Exobasidium, e.g., Exobasidium vexans; in the species Taphrina, e.g., Taphrina deformans; Woody plant degeneration diseases caused by the following: for example, Esca species, e.g., Phaeomoniella chlamydospora, Phaeoacremonium aleophilum, or Fomitiporia mediterranea; Ganoderma species, e.g., Ganoderma boninense; Diseases of flowers and seeds caused by the following, for example, Botrytis species, for example, Botrytis cinerea; Diseases of plant tubers caused by the following: for example, Rhizoctonia species, e.g., Rhizoctonia solani; Helminthosporium species, e.g., Helminthosporium solani; Diseases caused by the following bacterial pathogens, for example: Xanthomonas species, e.g., Xanthomonas campestris pv. oryzae; Pseudomonas species, e.g., Pseudomonas syringae pv. lachrymans; Erwinia species, e.g., Erwinia amylovora; Ralstonia species, e.g., Ralstonia solanacearum; Fungal diseases affecting the roots and stem bases caused by the following, for example: black root rot (Calonectria crotalariae), anthracnose (Macrophomina phaseolina), Fusarium wilt or Fusarium wilt, root rot, and pod and basal rot (Fusarium oxysporum, Fusarium orthoceras, Fusarium semitectum, Fusarium equiseti), Mycoleptodiscus root rot (Mycoleptodiscus terrestris), Neocosmospora vasinfecta, pod and leaf blight (Diaporthe phaseolorum), stem blight (Diaporthe phaseolorum var. caulivora), Phytophthora rot (Phytophthora megasperma), brown stem rot (Phialophora gregata), and Pythium rot. Pythium aphanidermatum, Pythium irregulare, Pythium debaryanum, Pythium myriotylum, Pythium ultimum), Rhizoctonia root rot, stem rot, and rot (Rhizoctonia solani), Sclerotinia stem rot (Sclerotinia sclerotiorum), Sclerotinia white mold (Sclerotinia rolfsii), Thielaviopsis root rot (Thielaviopsis basicola).

[0139] The following are examples of plants that can be treated according to the present invention: Rosaceae sp. (e.g., pears, e.g., apples, pears, apricots, cherries, almonds and peaches), Ribesioidae sp., Juglandaceae sp., Betulaceae sp., Anacardiaceae sp., Fagaceae sp., Moraceae sp., Oleaceae sp., Actinidaceae sp., Lauraceae sp., Musaceae sp. (e.g., banana trees and orchards), Rubiaceae sp. (e.g., coffee), Theaceae sp., Sterculiceae sp., Rutaceae sp. (e.g., lemons, oranges and grapefruits); Vitaceae sp. (e.g., grapes); Solanaceae sp. (e.g., tomatoes, peppers), Liliaceae sp., Asteraceae sp. (e.g., lettuce), Umbelliferae sp., Cruciferae sp., Chenopodiaceae sp., Cucurbitaceae sp. (e.g., cucumber), Alliaceae sp. (e.g., leek, onion), Papilionaceae sp. (e.g., legume); major crops, e.g., Poaceae / Gramineae sp. (e.g., maize, grass, grains, e.g., wheat, rye, rice, barley, oats, millet and rye), Asteraceae sp. (e.g., sunflower), Brassicaceae sp. (e.g., white cabbage, purple cabbage, broccoli, cauliflower, Brussels sprouts, bok choy, kohlrabi, radish, and rapeseed, mustard, horseradish and pepper grass), Fabacae sp. (e.g., legume, peanut), Papilionaceae sp. (e.g., soybean), Solanaceae sp. (e.g., potato), Chenopodiaceae sp. (e.g., sugar beet, mangelwart, Swiss chard, table beet); Malvaceae (e.g., cotton); plants useful for gardens and woodlands, and ornamental plants; and genetically modified varieties of each of these plants.

[0140] The pesticide mixtures or compositions containing the same of the present invention can be used for the curative or protective / preventive control of plant pathogenic fungi. Accordingly, the present invention also relates to a curative and protective method for controlling plant pathogenic fungi by using the pesticide mixtures or compositions containing the same of the present invention, wherein the pesticide mixtures or compositions containing the same of the present invention are applied to seeds, plants or plant parts on which plants grow, fruits or soil.

[0141] The present invention's biotoxic mixtures or compositions containing them are sufficiently tolerable by plants at concentrations required to control plant diseases, thus enabling treatment of plants, the above-ground parts of propagating plants and seeds, and soil.

[0142] All plants and plant parts can be processed according to the present invention. "Plants" means all plants and plant populations, e.g., desirable and undesirable wild-type plants, varieties and plant cultivars (whether or not they are protected by plant diversity or plant breeder rights). Varieties and plant species may be plants obtained by one or more biotechnological methods, e.g., by double haploids, plasmofusion, random and directional mutagenesis, by using molecular or genetic markers, or by conventional propagation and breeding methods that may be assisted or supplemented by bioengineering and genetic engineering methods. "Plant parts" means all above-ground and below-ground parts and organs of a plant, e.g., shoots, leaves, flowers and roots, and thus, e.g., leaves, needles, stems, branches, flowers, sporangia, fruits and seeds, as well as roots, cones and rhizomes. Crops and asexual and fertile reproductive materials, e.g., cuttings, cones, rhizomes, stolons and seeds, also belong to plant parts.

[0143] The pest-killing mixtures or compositions containing them of the present invention are suitable for protecting plants and plant organs to enhance yield and improve the quality of harvested material, provided they are well tolerated by plants, possess preferred thermotoxicity, and are well tolerated by the environment. They can preferably be used as crop protection compositions. They are typically active against susceptible and resistant species and at all or some developmental stages.

[0144] The following are some of the major crops that can be processed according to the present invention: corn, soybeans, alfalfa, cotton, sunflower, Brassica oilseeds such as Brassica napus (e.g., rapeseed), Brassica rapa, B. juncea (e.g., (field) mustard), and Brassica carinata, Arecaceae sp. (e.g., oil palm, coconut), rice, wheat, sugar beet, sugarcane, wild oats, rye, barley, grains, and sorghum, rye, flax, nuts, grapes, and climbing plants, as well as various fruits and plants from various plant taxa, such as Rosaceae sp. (e.g., pears, e.g., apples and pears, as well as drupes, e.g., apricots, cherries, almonds, plums and peaches, and berries, e.g., strawberries, raspberries, red and black currants and gooseberries), and Ribesioidae. sp., Juglandaceae sp., Betulaceae sp., Anacardiaceae sp., Fagaceae sp., Aforaceae sp., Oleaceae sp. (e.g., olive tree), Actinidaceae sp., Lauraceae sp. (e.g., avocado, cinnamon, camphor tree), Afusaceae sp. (e.g., banana tree and orchard), Rubiaceae sp. (e.g., coffee), Theaceae sp. (e.g., tea), Sterculiceae sp., Rutaceae sp. (e.g., lemon, orange, mandarin and grapefruit); Solanaceae sp. (e.g., tomato, potato, pepper, chili pepper, eggplant, tobacco), Liliaceae sp., Compositae sp. (e.g., chicory root, lettuce including endive or common chicory, artichoke and chicory), Umbelliferae sp. (e.g., carrots, parsley, celery and celery), Cucurbitaceae sp. (e.g., cucumbers: including gherkins, pumpkins, watermelons, gourds and melons), Alliaceae sp.(e.g., leeks and onions), Cruciferae sp. (e.g., white cabbage, purple cabbage, broccoli, cauliflower, Brussels sprouts, bok choy, kohlrabi, radish, horseradish, pepperwort and Chinese cabbage), Leguminosae sp. (e.g., peanuts, beans, lentils and legumes: e.g., common beans and broad beans), Chenopodiaceae sp. (e.g., Swiss chard, mangelhar, spinach, beet), Linaceae sp. (e.g., cannabis), Cannabeacea sp. (e.g., hemp), Malvaceae sp. (e.g., okra, cocoa), Papaveraceae (e.g., poppy), Asparagaceae (e.g., asparagus); useful and ornamental plants in gardens and forests, including turfgrasses, fungi, grasses and Stevia rebaudiana; as well as genetically modified types of these plants in each case. .

[0145] In particular, the pest-killing mixtures of the present invention or compositions containing them are suitable for controlling the following plant diseases: Albugo spp. (white rust): Occurs in ornamental plants, plants (e.g., A. candida) and sunflowers (e.g., A. tragopogonis); Alternaria spp. (alternaria leaf spot): Occurs in plants, rapeseed (A. brassicola or brassi cae), sugar beets (A. tenuis), fruits, rice, soybeans, potatoes (e.g., A. solani or A. alternata), tomatoes (e.g., A. solani or A. alternata) and wheat; Aphanomyces spp.: Occurs in sugar beets and plants; Ascochyta spp.: Occurs in cereals and plants, e.g., A. tritici (anthracnose): Occurs in wheat and A. hordei: Occurs in barley; Bipolaris and Drechslera spp. (teleomorph: Cochliobolus spp.), for example, Southern Leaf Bright (D. maydis) or Northern Leaf Bright (B. zeicola): maize, for example, leaf spot (B. sorokiniana): cereals, and for example, B. oryzae: rice and turf; Blumeria (formerly Erysiphe) graminis (powdery mildew): cereals (e.g., wheat or barley); Botrytis cinerea (Teleomorph: Botryotinia fuckeliana: gray mold): fruits and berries (e.g., strawberries), plants (e.g., lettuce, carrots, celery and cabbage), rapeseed, flowers, vines, forest plants and wheat; Bremia lactucae (downy mildew): occurs in lettuce; Ceratocystis (syn. Ophiostoma) spp. (rot or damping-off disease): broad-leaved and evergreen trees, e.g., C. ulmi (Ulmus dulcis): occurs on elms; Cercospora spp. (Cercospora leaf spot disease): occurs on corn (e.g., gray leaf spot disease: C. zeaemaydis), rice, sugar beets (e.g., C. beticola), sugarcane, plants, coffee, soybeans (e.g., C. sojina or C. kikuchil) and rice; Cladosporium spp.: tomatoes (e.g., C. fulvum: humus) and grains, e.g., C.herbarum (wheat slug): occurs on wheat; Claviceps purpurea (Ergot): occurs on cereals; Cochliobolus (anamorph: Helmin-thosporium of Bipolaris) spp. (leaf spot disease): occurs on maize (C. carbonum), cereals (e.g., C. sativus, anamorph: B. sorokiniana) and rice (e.g., C. miyabeanus, anamorph: H. oryzae); Colletotrichum (teleomorph: Glomerella) Corticium spp. (Anthracnose): Occurs in cotton (e.g., C. gossypit), corn (e.g., C. graminicola: anthracnose stem rot), fruits, potatoes (e.g., C. coccodes: black spot), plants (e.g., legumes (e.g., C. lindemuthianum) and soybeans (e.g., C. truncatum or C. gleosporioides); Corticium spp., e.g., C. sasakii (sheath blight): Occurs in rice; Corynespora cassiicola (leaf spot): Occurs in soybeans and ornamental plants; Cycloconium spp., e.g., C. oleaginum: Occurs in olive trees; Cyclindrocarpon spp. (e.g., fruit tree ulcer or grapevine weakness, teleomorph: Nectria or Neonectria) spp.): Occurs in fruit trees, climbing plants (e.g., C. liriodendri, teleomorph: Neonectria liriodendri: black foot disease) and ornamental plants; Dematophora (teleomorph: Rosellini) necatrix (root and stem rot): Occurs in soybeans; Diaporthe spp., e.g., D. phaseolorum (rot disease): Occurs in soybeans; Drechslera (syn. Helminthosporium, teleomorph: Pyrenophora) spp.: Occurs in maize, grains, e.g., barley (e.g., D. teres, net-like spot disease) and wheat (e.g., D. tritici-repentis: yellow-brown spot disease), rice and turf; Esca (canker, apoplexi): Occurs in climbing plants, Formitiporia (syn. Phellinus) punctata, F.Caused by mediterranea, Phaeomoniella chlamydospora (formerly Phaeocacremonium chlamydosporum), Phaeocacremonium aleophilum and / or Botryosphaeria obtusa; Elsinoe spp.: Occurs on pears (E. pyn), soft fruits (E. veneta: anthracnose) and climbing plants (E. ampelina: anthracnose); Entyloma oryzae (sooty mold): Occurs on rice; Epicoccum spp. (black mold): Occurs on wheat; Erysiphe spp. (powdery mildew): Occurs on sugar beets (E. betae), plants (e.g., E. pist), e.g., gourds (e.g., E. cichoracearum), cabbage, rapeseed (e.g., E. cruciferarum); Eutypa lata (Euonymus vine blight or canker, anamorph: Cytosporina lata, syn. Libertella blepharis): Occurs in fruit trees, climbing plants and ornamental plants; Exserohilum (syn. Helminthosporium) spp.: Occurs in corn (e.g., E. turcicum); Fusarium (teleomorph: Gibberella) spp. (damping-off, root or stem rot): Occurs in various plants, e.g., F. graminearum or F. culmorum (root rot, red mold or canker): Occurs in grains (e.g., wheat or barley); F. oxysporum: Tomato; F. solani (f. sp. glycines, now syn. F. virguliforme), as well as F. tucumaniae and F. brasiliense: Cause sudden death syndrome in soybeans, respectively; and F. verticillioides: Occurs in corn; Gaeumannomyces Graminis (damping-off disease): Occurs in cereals (e.g., wheat or barley) and maize; Gib berella spp.: Occurs in cereals (e.g., G. zeae) and rice (e.g., G. fujikuroi: bakanae disease); Glomerella cingulata: Occurs in climbing plants, pears and other plants, as well as G.gossypii: occurs on cotton; grain stain complex disease: occurs on rice; Guignardia bidwellii (black rot): occurs on climbing plants; Gymnosporangium spp.: occurs on rose family plants and juniper, e.g., G. sabinae (rust): occurs on pears; Helminthosporium spp. (syn. Drechslera, teleomorph: Cochliobolus): occurs on maize, grains and rice; Hemileia spp., e.g., H. vastatrix (coffee leaf rust): occurs on coffee; lsariopsis clavispora (syn. Cladosporiumvitis): occurs on climbing plants; Macrophonina Phaseolina (syn. phaseoft) (root and stem rot): occurs on soybeans and cotton; Microdochium (syn. Fusarium) nivale (pink snow rot): occurs on cereals (e.g., wheat or barley); Microsphaera diffusa (powdery mildew): occurs on soybeans; Monilinia spp., e.g., M. laxa, M. fructicola and M. fructigena (flower and twig blight, brown rot): occurs on drupes and other Rosaceae plants; Mycosphaerella spp.: occurs on cereals, bananas, soft fruits and ground nuts, e.g., M. graminicola (anamorph: Septoriatritici, Septoria leaf blight): occurs on wheat or M. fijiensis (black sigatoka disease): occurs on bananas; Peronospora spp. (downy mildew): occurs in cabbage (e.g., P. brassicae), rapeseed (e.g., P. parasitica), onions (e.g., P. destructor), tobacco (P. tabacina) and soybeans (e.g., P. manshurica); Phakopsora pachyrhizi and P. meibomiae (soybean rust): occurs in soybeans; Phialophora spp.: for example, climbing plants (e.g., P. tracheiphila and P. tetraspora) and soybeans (e.g., P.P. gregata (stem rot): occurs in rapeseed and cabbage, and P. betae (root rot, leaf spot and rot): occurs in sugar beets; Phomopsis spp.: occurs in sunflowers, climbing plants (e.g., P. viticola: stem and leaf spot) and soybeans (e.g., stem rot: P. phaseoli, teleomorph: Diaporthe phaseolorum); Physoderma maydis (brown spot): occurs in maize; Phytophthora spp. (damping-off, root, leaf, fruit and stem root): Occurs on various plants, e.g., bell peppers and gourds (e.g., P. capsic1), soybeans (e.g., P. megasperma, syn. P. sojae), potatoes and tomatoes (e.g., P. infestans: leaf blight) and broad-leaved trees (e.g., P. ramorum: oak sudden death); Plasmodiophora brassicae (clubroot): Occurs on cabbage, rapeseed, radishes and other plants; Plasmopara spp., e.g., P. viticola (grape downy mildew): Occurs on climbing plants, and P. halstedii: Occurs on sunflowers; Podosphaera spp. (powdery mildew): Occurs on rose family plants, hops, pears and soft fruits, e.g., P. leucotricha: Occurs on apples; Polymyxa spp., for example, occurs in cereals, such as barley and wheat (P. graminis) and sugar beets (P. betae), thereby transmitting viral diseases; Pseudocercosporella herpotrichoides (eye spot disease, teleomorph: Tapesia yallundae): occurs in cereals, for example, transmitted to wheat or barley; Pseudoperonospora (downy mildew): occurs in various plants, for example, P. cubensis: gourd or P. humili: hops; Pseudopezicula tracheiphila (color fireworks disease or Rottbrenner disease, anamorph: Philophora): occurs in climbing plants; Puccinia spp. (rust disease): occurs in various plants, for example, P. triticina (brown or leaf rust), P. striiformis (yellow rust), P.P. hordei (dwarf rust), P. graminis (stem or black rust), or P. recondita (brown or leaf rust): occurs on cereals, e.g., wheat, barley, or rye; P. kuehnii (orange rust): occurs on sugarcane and P. asparagi: occurs on asparagus; Pyrenophora (anamorph: Drechslera) tritici-repentis (yellowish-brown spot): occurs on wheat or P. teres (net spot): occurs on barley; Pyricularia spp.: e.g., P. oryzae (teres). Omorph: Magnaporthe grisea (rice leaf spot): Occurs on rice and P. grisea: Occurs on turf and grains; Pythium spp. (rot): Occurs on turf, rice, maize, wheat, cotton, rapeseed, sunflower, soybean, sugar beet, plants and various other plants (e.g., P. ultimum or P. aphanidermatum); Ramu / aria spp., e.g., R. collocygni (Ramuaria leaf spot, physiological leaf spot): Occurs on barley and R. beticola: Occurs on sugar beet; Rhizoctonia spp.: Cotton, rice, potatoes, grass, corn, rapeseed, potatoes, sugar beets, plants and various other plants, for example, R. solani (root and stem rot): soybeans, R. solani (sheath blight): rice or R. cerealis (Rhizoctonia spring blight): occurs on wheat or barley; Rhizopus stolonifer (black mold, soft rot): occurs on strawberries, carrots, cabbage, vines and tomatoes; Rhynchosporium secalis (burn): occurs on barley, rye and rye; Sarocladium oryzae and S. attenuatum (coat rot): occurs on rice; Sclerotinia spp. (stem rot or white mold): occurs in plants and crops, e.g., rapeseed, sunflower (e.g., S. sclerotiorum) and soybean (e.g., S. rolfsii or S. sclerotiorum); Septoria spp.: occurs in various plants, e.g., S. glycines (brown spot): soybean, S. tritici (septoria leaf blight): wheat and S. (syn. Stagonospora) nodorum (stagonospora leaf blight): occurs in cereals; Uncinula (syn. Erysiphe) necator (powdery mildew, anamorph: Oidium tucken): occurs in climbing plants; Setospaeria spp. (leaf blight): occurs in maize (e.g., S. turcicum, syn. Helminthosporium turcicum) and turf; Sphacelotheca spp. (sooty mold): occurs in maize, (e.g., S.reiliana (sooty mold): occurs on sorghum and sugarcane; Sphaerotheca fuliginea (powdery mildew): occurs on gourds; Spongospora subterranea (skin scabies): occurs on potatoes and is a viral disease transmitted by them; Stagonospora spp.: occurs on cereals, e.g., S. nodorum (Stagonospora leaf blight, teleomorph: Lepto sphaeria [syn. Phaeosphaeria] nodorum): occurs on wheat; Synchytrium endobioticum: occurs on potatoes (potato warts); Taphrina spp., e.g., T. deformans (leaf curl): occurs on peaches and T. pruni (plum pocket): occurs on plums; Thielaviopsis spp. (black root rot): occurs on tobacco, pears, plants, soybeans and cotton, e.g., T. basicola (syn. Chalara Occurs in elegans; Tilletia spp. (common smut or smut): cereals, e.g., T. tritici (syn. T. caries, wheat smut) and T. controversa (dwarf smut): occurs in wheat; Typhula incamata (gray snow mold): occurs in barley or wheat; Urocystis spp.: e.g., U. occulta (sooty mold): occurs in rye; Uromyces spp. (rust): occurs in plants, e.g., legumes (e.g., U. appendiculatus, syn. U. phaseoft) and sugar beets (e.g., U. betae); Ustilago spp. (naked smut): occurs in cereals (e.g., U. nuda and U. avaenae), maize (e.g., U. maydis: maize sooty mold) and sugarcane; Venturia Verticillium spp. (Red mold disease): Occurs on apples (e.g., V. inaequalis) and pears; and Verticillium spp. (Dampness disease): Occurs on various plants, such as fruit and ornamental plants, vines, soft fruits, plants, and crops, such as V. dahliae: Occurs on strawberries, rapeseed, potatoes, and tomatoes.

[0146] formulation The bio-toxic mixture of the present invention can be converted into conventional formulations, such as solutions, emulsions, suspensions, dusts, powders, pastes, and granules. The form of use depends on the specific intended purpose. In each case, the fine and uniform distribution of the compounds in the mixture should be ensured.

[0147] Therefore, the present invention also relates to an auxiliary agent and a pesticide mixture comprising the pesticide mixture of the present invention.

[0148] The agricultural chemical composition contains an effective amount of the pest-killing active mixture of the present invention. The term "effective amount" refers to the amount of composition or mixture that is sufficient to control pests harmful to cultivated plants or to protect materials without causing substantial damage to the treated plants. Such amounts can vary widely and depend on various factors, such as the species of animal pest to be controlled, the cultivated plants or materials being treated, climatic conditions, and the specific mixture used.

[0149] The pest-killing mixture of the present invention can be converted into conventional types of agricultural chemical compositions, such as liquids, emulsions, flowables, powders, pastes, granules, compression molds, capsules, and mixtures thereof. Examples of compositional forms include flowables (SC, suspension concentrate), oil dispersants (OD, oil dispersion), emulsifiable concentrates (e.g., EC&EW), microemulsions (ME), capsules (e.g., CS), pastes, pastels, wettable powders or powders (e.g., WP, SP, WS, DP, DS), compression molds (e.g., BR, TB, DT), granules (e.g., WG, SG, GR, FG, GG, MG), and gels. Other formulations for delivering the mixed active substance are ZC, ZE, and ZW. The delivery of individual or mixed components for seed treatment can be formulated via the FS format. These and further composition types are defined in the "Catalogue of pesticide formulation types and International coding system," Technical Monograph No. 2, 6th edition, May 2008, CropLife International.

[0150] The compositions are prepared by known methods, for example, Mollet and Grubemann, Formulation Technology, Wiley VCH, Weinheim, 2001; or Knowles, New Developments in Crop Protection Product Formulation, Agrow Reports DS243, T&F Informa, London, 2005.

[0151] Examples of suitable auxiliaries or agriculturally acceptable auxiliaries are solvents, liquid carriers, solid carriers or fillers, surfactants, dispersants, emulsifiers, wetting agents, spreading agents, adjuvants, solubilizers, transdermal absorption promoters, protective colloids, adhesives, thickeners, humectants, repellents, attractants, feeding stimulants, compatibilizers, bactericides, antifreezing agents, defoaming agents, colorants, tackifiers and binders.

[0152] Suitable solvents and liquid carriers are water and organic solvents, for example, low molecular weight mineral oil fractions of medium to high boiling point, such as paraffin, oils of vegetable or animal origin; aliphatic, cyclic and aromatic hydrocarbons, such as toluene, paraffin, tetrahydronaphthalene, alkylated d naphthalene; alcohols, such as ethanol, propanol, butanol, benzyl alcohol, cyclohexanol; glycols; DMSO; ketones, such as cyclohexanone; esters, such as lactic acid, carbonate, fatty acid esters, gamma-butyrolactone; fatty acids; phosphonates; amines; amides, such as N-methylpyrrolidone, fatty acid dimethylamide, dimethylformamide (DMF), and mixtures thereof.

[0153] Suitable solid carriers or fillers are mineral earths, such as silicates, silica gel, talc, kaolin, limestone, lime, chalk, clay, dolomite, diatomaceous earth, bentonite, calcium sulfate, magnesium sulfate, magnesium oxide; polysaccharides, such as cellulose, starch; fertilizers, such as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea; products of plant origin, such as cereal meal, bark meal, sawdust, nut shell meal, and mixtures thereof.

[0154] Suitable surfactants include surface-active compounds, such as anionic, cationic, nonionic, and amphoteric surfactants; ethoxylated aliphatic alcohols or their esters; ethoxylated-propoxylated aliphatic alcohols and their esters; aliphatic alcohol methyl esters; aliphatic alcohol methyl ester ethoxylates; EO-PO block copolymers; alkyl polyglucosides; polyelectrolytes; and mixtures thereof. Such surfactants can be used as emulsifiers, adjuvants, dispersants, solubilizers, wetting agents, transdermal absorption enhancers, and protective colloids. Examples of surfactants are listed in McCutcheon's, Vol. 1: Emulsifiers & Detergents, McCutcheon's Directories, Glen Rock, USA, 2008 (International or North American edition).

[0155] Suitable anionic surfactants are alkalis, alkaline earths, or ammonium salts of sulfonates, sulfates, phosphates, carboxylates, and mixtures thereof. Examples of sulfonates include alkylaryl sulfonates, diphenyl sulfonates, alpha-olefin sulfonates, lignosulfonates, sulfonates of fatty acids and oils, sulfonates of ethoxylated alkylphenols, sulfonates of alkoxylated arylphenols, sulfonates of condensed naphthalene, sulfonates of dodecylbenzene and tridecylbenzene, sulfonates of naphthalene and alkylnaphthalene, sulfosuccinates, or sulfosuccinates.

[0156] Suitable nonionic surfactants include alkoxylates, N-substituted fatty acid amides, amine oxides, esters, sugar-based surfactants, polymeric surfactants, and mixtures thereof. Examples of alkoxylates are compounds alkoxylated in amounts from 1 to 50 equivalents, such as alcohols, alkylphenols, amines, amides, arylphenols, fatty acids, or fatty acid esters. Ethylene oxide and / or propylene oxide can be used for alicoxation, preferably ethylene oxide. Examples of N-substituted fatty acid amides are fatty acid glucamides or fatty acid alkanolamides.

[0157] Examples of esters include fatty acid esters, glycerol esters, or monoglycerides. Examples of sugar-based surfactants include sorbitan, ethoxylated sorbitan, sucrose and glucose esters, or alkyl polyglucosides. Examples of polymeric surfactants include homopolymers or copolymers of vinylpyrrolidone, vinyl alcohol, or vinyl acetate.

[0158] Suitable cationic surfactants are quaternary surfactants, such as quaternary ammonium compounds having one or two hydrophobic groups, or salts of long-chain primary amines. Suitable amphoteric surfactants are alkyl betaines and imidazolines. Suitable block polymers are AB-type or ABA-type block polymers containing blocks of polyethylene oxide and polypropylene oxide, or ABC-type block polymers containing alkanols, polyethylene oxide and polypropylene oxide.

[0159] Suitable polyelectrolytes are polyacids or polybases. Examples of polyacids are polyacrylic acid or alkali salts of polyacid comb polymers. Examples of polybases are polyvinylamine or polyethyleneamine. Suitable adjuvants are compounds that have negligible biocidal activity or no biocidal activity at all, and that improve the biological performance of compound I or the mixture according to the present invention against a target. Examples include surfactants, minerals or vegetable oils, and other additives. Further examples are listed in Knowles, Adjuvants and Additives, Agrow Reports DS256, T&F Informa UK, 2006, Chapter 5.

[0160] Suitable thickeners include polysaccharides (e.g., xanthan gum, carboxymethylcellulose), clay, kaolin (organically modified or unmodified), polycarboxylates, and silicates.

[0161] Appropriate isothiazolinone derivatives of fungicides, such as alkylisothiazolinone and benzoisothiazolinone, are included to inhibit the growth of bacteria and fungi.

[0162] Suitable antifreeze agents include ethylene glycol, propylene glycol, and glycerin.

[0163] Suitable defoaming agents include silicones, long-chain alcohols, and fatty acid salts.

[0164] Appropriate colorants, namely low water-soluble dyes and pigments as well as water-soluble dyes, are used for identification and signaling to consumers. Examples include inorganic colorants (e.g., iron oxide, titanium dioxide, iron hexacyanoferrate) and organic colorants (e.g., alizarin-, azo-, and phthalocyanine colorants).

[0165] In many cases, thickeners and rheological modifiers used for acceptable consumer-favorable properties include polyvinylpyrrolidone, polyvinyl acetate, polyvinyl alcohol, polyacrylates, biological or synthetic waxes, carboxymethylcellulose and cellulose ethers or guar gum, or derivatives thereof, which are used as thickeners and rheological modifiers.

[0166] Examples of the types of compositions and their preparations are as follows: i) Water-soluble concentrates (SL, LS) Dissolve 10-60% by weight of the biotoxic mixture of the present invention and 5-15% by weight of a wetting agent (e.g., alcohol alkoxylate) in up to 100% by weight of water and / or a water-soluble solvent. The active substance dissolves upon dilution with water.

[0167] ii) Emulsion (EC) Dissolve 15-70% by weight of the biotoxic mixture of the present invention and 5-10% by weight of an emulsifier (e.g., calcium dodecylbenzenesulfonate and castor oil ethoxylate) in up to 100% by weight of a water-insoluble organic solvent (e.g., aromatic hydrocarbon). Dilute with water to obtain an emulsion.

[0168] iii) Emulsion formulation (EW) Mix 5-40% by weight of the biotoxic mixture of the present invention and 1-10% by weight of the emulsifier MW5000-1000 EO-PO copolymer with an organic solvent (5-75%) (e.g., dilute paraffin) and water (10-80%) to produce a translucent or light-shielding mixture. Add water to this mixture to produce an emulsion of the active substance in water. Dissolve this in 20-40% by weight of a water-insoluble organic solvent (e.g., aromatic hydrocarbon). Using an emulsifier, introduce this mixture into water up to 100% by weight to make a homogeneous emulsion. Dilution with water yields the emulsion.

[0169] iv) Flowable formulations (SC) In a stirred ball mill, 20 to 60% by weight of the pesticidal active mixture of the present invention is finely ground by adding 2 to 10% by weight of a dispersant and wetting agent (for example, sodium lignosulfonate and alcohol ethoxylate), 0.1 to 2% by weight of a thickener (for example, xanthan gum) and up to 100% by weight of water to obtain a fine active substance suspension. By dilution with water, a stable suspension of the active substance is obtained. For FS-type compositions, up to 40% by weight of a binder (for example, polyvinyl alcohol) is added.

[0170] v) Water-dispersible granules and water-soluble granules (WG, SG) By adding up to 100% by weight of a dispersant and wetting agent (for example, sodium lignosulfonate and alcohol ethoxylate), 50 to 80% by weight of the pesticidal active mixture of the present invention is finely ground and prepared as water-dispersible or water-soluble granules using an industrial apparatus (for example, extrusion, spray tower, fluid bed). By dilution with water, a stable dispersion or solution of the active substance is obtained.

[0171] vi) Water-dispersible powders and water-soluble powders (WP, SP, WS) By adding 1 to 5% by weight of a dispersant (for example, sodium lignosulfonate), 1 to 3% by weight of a wetting agent (for example, alcohol ethoxylate) and up to 100% by weight of a solid carrier, for example silica gel, 50 to 80% by weight of the pesticidal active mixture of the present invention is ground in a rotor-stator mill. By dilution with water, a stable dispersion or solution of the active substance is obtained.

[0172] vii) Gel formulations (GW, GF) In a stirred ball mill, 5 to 25% by weight of the pesticidal active mixture of the present invention is finely ground by adding 3 to 10% by weight of a dispersant (for example, sodium lignosulfonate), 1 to 5% by weight of a thickener (for example, carboxymethyl cellulose) and up to 100% by weight of water to obtain a fine suspension of the active substance. By dilution with water, a stable suspension of the active substance is obtained.

[0173] viii) Microemulsion (ME) Add 5-20% by weight of the toxic bioactive mixture of the present invention to 5-30% by weight of an organic solvent blend (e.g., fatty acid dimethylamide and cyclohexanone), 10-25% by weight of a surfactant blend (e.g., alcohol ethoxylate and arylphenol ethoxylate), and an auxiliary surfactant (1-10%) (e.g., aliphatic alcohol or long-chain alkyl ester) and up to 100% water. Stir this mixture for 1 hour to spontaneously generate a thermodynamically stable microemulsion.

[0174] ix) Microcapsules (CS) An oil phase containing 5-50% by weight of the biocidal mixture of the present invention, 0-40% by weight of a water-insoluble organic solvent (e.g., aromatic hydrocarbon), and 2-15% by weight of an acrylic monomer (e.g., methyl methacrylate, methacrylic acid, and diacrylate or triacrylate) is dispersed in an aqueous solution of a protective colloid (e.g., polyvinyl alcohol). Radical polymerization initiated by a radical initiator results in the formation of poly(meth)acrylate microcapsules. Alternatively, an oil phase containing 5-50% by weight of Compound I according to the present invention, 0-40% by weight of a water-insoluble organic solvent (e.g., aromatic hydrocarbon), and an isocyanate monomer (e.g., diphenylmethene-4,4'-diisocyanate) is dispersed in an aqueous solution of a protective colloid (e.g., polyvinyl alcohol). The addition of a polyamine (e.g., hexamethylenediamine) results in the formation of polyurea microcapsules. The monomer reaches 1-10% by weight. The weight percentages are relative to the total CS composition.

[0175] x) Dustable powder (DP, DS) The pest-killing biological activity mixture of the present invention is finely ground in an amount of 1 to 10% by weight and densely mixed with a solid carrier of up to 100% by weight, such as finely divided kaolin.

[0176] xi) Granules (GR, FG) A 0.5-30% by weight mixture of the pest-killing active ingredient of the present invention is finely ground and combined with up to 100% by weight of a solid carrier (e.g., silicate). Granules are produced by extrusion, spray drying, or fluidized bed drying.

[0177] xii) Ultra low volume liquid (UL) Dissolve 1 to 50% by weight of the biotoxic mixture of the present invention in up to 100% by weight of an organic solvent, such as an aromatic hydrocarbon.

[0178] The pest-killing composition generally contains between 0.01 and 95% of the active substance, preferably between 0.1 and 90%, and particularly between 0.5 and 75% by weight. The active substance is used with a purity of 90% to 100%, preferably between 95% and 100% (according to the NMR range).

[0179] In one embodiment, the saspo formulation (SC) is preferred for application in crop protection. In one lower embodiment, the SC agricultural chemical composition comprises 50 to 500 g / L (grams per liter), or 100 to 250 g / L, or 100 g / L, 150 g / L, 200 g / L, or 250 g / L.

[0180] Water-soluble concentrates (LS), suspend emulsions (SE), fluid concentrates (FS), powders for drying (DS), water-dispersible powders for slurry treatment (WS), water-soluble powders (SS), emulsions (ES), emulsions (EC), and gels (GF) are commonly used for the treatment of plant propagation materials, particularly seeds. The compositions in question yield ready-to-use preparations with active substance concentrations of 0.01 to 60% by weight, preferably 0.1 to 40% by weight, after 2 to 10-fold dilution.

[0181] Application can be carried out before or during sowing. Methods for applying the pesticide-active mixture and its compositions of the present invention to plant propagation materials, particularly seeds, include powdering, coating, pelletizing, scattering, dipping, and inter-row application of the propagation material. Preferably, the pesticide-active mixture or its compositions of the present invention are applied to plant propagation materials in a manner that does not induce germination, such as by seed powdering, pelletizing, coating, and scattering.

[0182] When used for plant protection, the amount of active substance applied is 0.001 to 5 kg per hectare, preferably 0.001 to 2 kg per hectare, more preferably 0.005 to 1 kg per hectare, and particularly 0.005 to 0.5 kg per hectare, depending on the type of effect desired.

[0183] For example, in the treatment of plant propagation materials, such as seeds, by dusting, coating, or drenching the seeds, an amount of active substance of 0.1 to 1000 g, preferably 0.1 to 300 g, more preferably 0.1 to 100 g, and most preferably 0.25 to 100 g per 100 kilograms of plant propagation material (preferably seeds) is generally required.

[0184] When used for protecting materials or stored products, the amount of active substance applied depends on the type of application area and the desired effect. In protecting materials, the amount typically applied is 0.001 g to 2 kg, preferably 0.005 g to 1 kg, of the active substance per cubic meter of material being treated.

[0185] Various types of oils, wetting agents, adjuvants, fertilizers, or micronutrients, and other pesticides (e.g., herbicides, insecticides, fungicides, growth regulators, toxicity mitigators, biological pesticides) can be added to the active substance or a composition containing them as a premix, or, if appropriate, immediately before use (tank mix). These agents can be mixed with the composition according to the present invention in a weight ratio of 1:100 to 100:1, preferably 1:10 to 10:1.

[0186] Biological pesticides are typically produced by growing and concentrating naturally occurring organisms and / or their metabolites, including bacteria and other microorganisms, fungi, viruses, nematodes, and proteins. They are often considered essential components of integrated pest management (IPM) programs and have garnered considerable practical attention as alternatives to synthetic chemical plant protection products (PPPs).

[0187] Another aspect of the present invention is that when preparing the mixture, it is preferable to use a mixture according to the present invention in which, for example, further active compounds that are effective against harmful fungi or have herbicidal activity, or growth regulators or fertilizers can be added.

[0188] The compositions of the present invention may further contain active ingredients other than those listed above. For example, fungicides, herbicides, fertilizers, such as ammonium nitrate, urea, potassium carbonate, and superphosphates, plant toxins, plant growth regulators, and toxicity mitigators. These additional ingredients may be used sequentially or in combination with the compositions described above, and may even be added only immediately before use (tank mix), if appropriate. For example, plants may be sprayed with the compositions of the present invention before or after treatment with other active ingredients.

[0189] Applicable Due to their excellent activity, the pest-killing mixture or composition containing the mixture according to the present invention can be used to control invertebrate pests and / or plant pathogenic fungi.

[0190] The pesticide mixture according to the present invention, comprising the compound of formula (I) and an insecticidal compound (II) or a fungicidal compound (III), can be applied simultaneously, i.e., together or separately, or sequentially, i.e., one immediately after the other, thereby creating an "in-situ" mixture at the desired location (e.g., plants) and in the desired order (in the case of separate applications) without affecting the overall outcome of the control measures.

[0191] In two-component mixtures, the pesticide mixture and compositions according to the present invention, comprising the compound of formula (I) and an insecticidal compound (II) or a fungicidal compound (III), are typically applied in weight ratios of 5000:1 to 1:5000, preferably 1000:1 to 1:1000, more preferably 500:1 to 1:500 and 125:1 to 1:125, particularly preferably 25:1 to 1:25, and especially preferably 10:1 to 1:10, 5:1 to 1:5, 3:1 to 1:3 or 2:1 to 1:2. In such two-component mixtures, compounds (I) and (II) or (III) may be used in equal amounts, or an excess of compound (I) or an excess of compound (II) or (III) may be used.

[0192] Depending on the desired effect, the application rate of the mixture according to the present invention is 5 g / ha to 5000 g / ha, preferably 0.5 g / ha to 1000 g / ha, more preferably 1 g / ha to 750 g / ha, and particularly 5 g / ha to 500 g / ha and 5 g / ha to 200 g / ha.

[0193] The present invention provides for a composition containing a bio-toxic mixture or mixture that is effective through both contact and ingestion.

[0194] The pest-killing active mixture or composition containing the mixture according to the present invention can be applied to any and all developmental stages, such as egg, larva, pupa, and adult stages. Pests can be controlled by bringing the target pest, its food source, habitat, breeding ground, or habitat into contact with a pest-killing effective amount of the pest-killing active mixture or composition containing the mixture according to the present invention.

[0195] According to a preferred embodiment, the present invention provides for the protection of crops, particularly living plants, by using a combination of pest-killing biologically active mixtures or compositions comprising such mixtures.

[0196] According to another specific embodiment of the present invention, the pest-killing bioactive mixture according to the present invention is utilized by application to soil. Application to soil is particularly preferred for use against ants, termites, crickets, or cockroaches.

[0197] According to another embodiment of the present invention, for use against non-crop pests, such as ants, termites, wasps, flies, mosquitoes, crickets, grasshoppers, or cockroaches, the pest-killing mixture according to the present invention is prepared in a bait preparation.

[0198] The bait can be a liquid, solid, or semi-solid preparation (e.g., a gel).

[0199] Animal pests (also called “invertebrate pests”), i.e., insects, arachnids and nematodes, plants in which plants grow, soil or water, can be brought into contact with the biocidal mixture or composition according to the present invention, which includes the mixture, by any application method known in the art. Thus, “contact” includes both direct contact (applying the compound / composition directly to animal pests or plants, usually to the leaves, stems or roots of plants) and indirect contact (applying the compound / mixture / composition to the habitat of animal pests or plants).

[0200] The pest-killing mixture or pest control composition containing the mixture according to the present invention can be used to protect growing plants and crops from attacks or parasitism by animal pests, particularly insects, mites, or arachnids, by contacting the plants / crops with an effective amount of the mixture according to the present invention. The term "crops" refers to both growing crops and harvested crops.

[0201] The present invention relates to a pest-killing mixture and a composition containing the mixture, which can be used to kill various cultivated plants, such as grains, root vegetables, oil crops, plants, spices, ornamental plants, such as durum wheat and other wheat seeds, barley, oats, rye, corn (feed corn and sugar corn / sweet and field corn), soybeans, oil crops, cruciferous plants, cotton, sunflowers, bananas, rice, rapeseed, rapeseed, sugar beets, and more. It is particularly important for controlling numerous insects on plants such as basil, eggplant, potato, grasses, mycelium, turf, fodder grasses, tomato, leek, pumpkin / squash, cabbage, iceberg lettuce, pepper, cucumber, melon, rapeseed, legumes, garlic, onion, carrot, tuberous plants, such as potato, sugarcane, tobacco, grape, petunia, geranium / baby grass, pansy, and impatiens.

[0202] The insecticidal bioactive mixture according to the present invention is used either as is or in composition form by treating insects or plants, plant propagation materials, such as seeds, soil, surfaces, materials, or rooms that should be protected from insecticidal attacks, with an insecticidal effective amount of the active compound. Application can be carried out both before and after the plants, plant propagation materials, such as seeds, soil, surfaces, materials, or rooms, are infected by insects.

[0203] The present invention also includes a method for controlling animal pests, comprising contacting animal pests, their habitats, breeding grounds, food sources, cultivated plants, seeds, soil, areas, materials or environments (where animal pests grow or can grow), or materials, plants, seeds, soil, surfaces or spaces that should be protected from animal attacks or parasitism, with a mixture of at least one active compound I and at least one active compound II in an effective amount for killing pests.

[0204] Furthermore, animal pests can be controlled by bringing the target pest, its food source, habitat, breeding ground, or habitat into contact with a biokilling amount of the mixture according to the present invention. Therefore, application may be carried out before or after habitats, growing crops, or harvested crops are infected by pests.

[0205] The pest-killing active mixture or composition comprising the mixture according to the present invention can also be applied preventively to locations where pest outbreaks are expected.

[0206] The pest-killing active mixture or composition comprising the mixture according to the present invention may also be used to protect growing plants from attacks or parasitism by pests by exposing the plants to a pest-killing effective amount of the mixture according to the present invention. Thus, “exposure” includes both direct contact (applying the compound / composition directly to pests and / or plants, usually to the leaves, stems, or roots of the plant) and indirect contact (applying the mixture / composition according to the present invention to the habitat of pests and / or plants).

[0207] "Habitat" means a habitat, breeding ground, plant, seed, soil, area, material, or environment in which a harmful or parasitic organism grows or can grow.

[0208] The term “plant propagation material” shall be considered to represent all reproductive parts of a plant that can be used for plant propagation, e.g., seeds and asexual plant materials, e.g., cuttings and tubers (e.g., potatoes). This includes plant seeds, roots, fruits, tubers, bulbs, rhizomes, shoots, buds and other parts. Seedlings and saplings, which are to be transplanted after germination or emergence from the soil, may also be included. These plant propagation materials may be prophylactically treated with plant protection compounds at the time of planting or transplanting or at any time prior to that.

[0209] The term "cultivated plants" shall be understood to include plants that have been modified through breeding, mutation, or genetic engineering. Genetically modified plants are plants that have genetic material that has been modified in such a way as not to be readily obtained in the natural environment through crossbreeding, mutation, or natural recombination, by the use of recombinant DNA techniques. Typically, one or more genes are integrated into the genetic material of a genetically modified plant to improve a particular trait of the plant. Such genetic modifications also include, but are not limited to, targeted post-translational modifications of proteins (oligopeptides or polypeptides), such as glycosylation or polymerization, such as prenylation, acetylation, or farnesylation or PEG moieties (e.g., Biotechnol Prog. July-August 2001; Vol. 17 (No. 4): pp. 720-728; Protein Eng Des Sel. January 2004; Vol. 17 (No. 1): pp. 57-66; Nat Protoc. 2007; Vol. 2 (No. 5): pp. 1225-1235; Curr Opin Chem Biol., October 2006; Vol. 10 (No. 5): pp. 487-491; Epub August 28, 2006; Biomaterials. March 2001; Vol. 22 (No. 5): pp. 405-417; Bioconjug As disclosed in Chem. January-February 2005; Vol. 16 (No. 1): pp. 113-1121).

[0210] The term “cultivated plants” is understood to include plants that have been conferred resistance to the application of certain classes of herbicides, e.g., hydroxyphenylpyrubate dioxygenase (HPPD) inhibitors; acetolactic acid synthase (ALS) inhibitors, e.g., plants conferred resistance to the application of sulfonylurea as a result of conventional breeding or genetic engineering (e.g., U.S. Patent Nos. 6,222,100, WO01 / 82685, WO00 / 26390, WO97 / 41218, WO98 / 02526, WO98 / 02527, WO04 / 106529, WO05 / 20673, WO03 / 14357, WO03 / 13225, WO03 / 14356, WO04 / 16073) or imidazolinone (e.g., U.S. Patent No. 6,222 See No. 100, WO01 / 82685, WO00 / 26390, WO97 / 41218, WO98 / 02526, WO98 / 02527, WO04 / 106529, WO05 / 20673, WO03 / 14357, WO03 / 13225, WO03 / 14356, WO04 / 16073); Enolpyruvicishikimic acid-3-phosphate EPSPS inhibitors, e.g., glyphosate (see, e.g., WO92 / 00377); glutamine synthetase (GS) inhibitors, e.g., glufosinate (see, e.g., EP-A-0242236, EP-A-242246); or oxynyl herbicides (see, e.g., U.S. Patent No. 5,559,024). Some cultivated plants have been conferred to tolerate herbicides through conventional breeding (mutation); for example, Clearfield® summer rapeseed (Brassica napus) is tolerant to imidazolinone, e.g., imazamox. Using genetic engineering techniques, cultivated plants such as soybeans, cotton, corn, beets, and rapeseed have been given tolerance to herbicides such as glyphosate and glufosinate, some of which are marketed under the trademark names RoundupReady® (glyphosate) and LibertyLink® (glufosinate).

[0211] The term "cultivated plants" refers to those known by the use of recombinant DNA techniques, particularly from the bacterial genus Bacillus, especially from Bacillus thuringiensis, e.g., α-endotoxins, e.g., CryIA(b), CryIA(c), CryIF, CryIF(a2), CryIIA(b), CryIIIA, CryIIIB(b1) or Cry9c; vegetative long-term secretory insecticidal proteins (VIPs), e.g., VIP1, VIP2, VIP3 or VIP3A; insecticidal proteins of bacterial colony-forming nematodes, e.g., Photorhabdus spp. or Xenorhabdus spp.; Toxins produced by animals, e.g., scorpion venom, arachnid venom, wasp venom, or other insect-specific neurotoxins; Toxins produced by fungi, e.g., streptomicetes toxin; Plant lectins, e.g., bean or barley lectin; Agglutinin; Protease inhibitors, e.g., trypsin inhibitors, serine protease inhibitors, patatin, cystatin, or papain inhibitors; Ribosome-inactivating proteins (RIPs), e.g., lysine, maize-RIP, abrin, rufin, saporin, or briodin; Steroid metabolic enzymes It is understood that the invention includes plants capable of synthesizing one or more insecticidal proteins from elements such as 3-hydroxysteroid oxidase, ecdysteroid-IDP-glycosyl-transferase, cholesterol oxidase, ecdysone inhibitor, or HMG-CoA-reductase; ion channel blockers, such as sodium or calcium channel blockers; juvenile hormone esterase; diuretic hormone receptor (helicokinin receptor); stilbene synthase, vibenzyl synthase, chitinase, or glucanase. In the context of the invention, these insecticidal proteins or toxins are also understood explicitly as pretoxins, hybrid proteins, terminally cleaved, or otherwise modified proteins. Hybrid proteins are characterized by novel combinations of protein domains (see, for example, WO02 / 015701).Further examples of such toxins or genetically modified plants capable of synthesizing such toxins are disclosed, for example, in EP-A374753, WO93 / 007278, WO95 / 34656, EP-A427529, EP-A451878, WO03 / 018810 and WO03 / 052073.

[0212] Methods for producing such genetically modified plants are generally known to those skilled in the art and are described, for example, in the publications mentioned above. These insecticidal proteins are contained in genetically modified plants and provide the plants that produce these proteins with protection from harmful pests of certain taxonomic groups of arthropods, particularly beetles (Coleoptera), flies (Diptera), butterflies and moths (Lepidoptera), and plant parasitic nematodes (Nematodae).

[0213] The term “cultivated plants” is understood to include plants that, by the use of recombinant DNA techniques, are capable of synthesizing one or more proteins that increase their resistance or tolerance to bacterial, viral, or fungal pathogens. Examples of such proteins include so-called “pathogenicity-associated proteins” (PR proteins, see, e.g., EP-A0392225), plant disease resistance genes (e.g., potato varieties expressing resistance genes that act against Phytophthora infestans derived from the Mexican wild potato Solanum bulbocastanum), or T4-lysozym (e.g., potato varieties capable of synthesizing these proteins that have higher resistance to bacteria, e.g., Erwinia amylvora). Methods for producing such genetically modified plants are generally known to those skilled in the art and are described, for example, in the publications mentioned above.

[0214] The term “cultivated plants” shall be understood to include plants that, by the use of recombinant DNA techniques, are capable of synthesizing one or more proteins that increase productivity (e.g., biomass production, grain yield, starch content, oil content, or protein content), tolerance to drought, salinity, or other environmental growth limiting factors, or tolerance to pests and fungi, bacterial or viral pathogens.

[0215] The term “cultivated plants” is understood to include plants that contain modified or novel substances through the use of recombinant DNA techniques, specifically oil crops (e.g., Nexera® rapeseed) that produce health-promoting long-chain omega-3 fatty acids or unsaturated omega-9 fatty acids for improving the nutrition of humans or animals.

[0216] The term “cultivated plants” shall be understood to include plants that contain modified or novel substances through the use of recombinant DNA techniques, specifically, potatoes that produce greater amounts of amylopectin (e.g., Amflora® potatoes) to improve raw material production.

[0217] Generally, "effective pest-killing amount" refers to the amount of the active ingredient or mixture according to the present invention required to achieve an observable effect on growth, which includes effects such as necrosis, death, delay, prevention, and removal, destruction, or otherwise reduction of the occurrence and activity of the target organism. The effective pest-killing amount may vary for the various mixtures / compositions used in the present invention. The composition of the effective pest-killing amount will also vary according to general conditions, such as the desired pest-killing effect and duration, weather, target species, habitat, mode of application, etc.

[0218] For foliar treatment, the amount of active ingredient is in the range of 0.01 to 5000 g per hectare, for example, 0.1 g to 2000 g or 1 g to 500 g per hectare, preferably 10 g to 200 g per hectare, preferably 15 to 100 g per hectare, or 20 to 80 g per hectare, or 10 to 60 g per hectare, or 20 to 50 g per hectare, or 30 to 50 g per hectare, or 40 to 50 g per hectare.

[0219] For soil treatment or application to the habitat or nests of pests, the amount of active ingredient is 100m 2 0.0001 to 500g per serving, preferably 100ml 2 The range is 0.001 to 20g per serving.

[0220] A typical application rate for protecting materials is, for example, 1 m of treated material. 2 0.01g to 1000g of the active compound per unit, preferably 1m 2 Each serving contains between 0.1g and 50g.

[0221] Insecticide compositions for use in impregnation of materials typically contain 0.001 to 95% by weight, preferably 0.1 to 45% by weight, and more preferably 1 to 25% by weight of at least one repellent and / or insecticide.

[0222] The biologically active mixture or composition containing the mixture according to the present invention is effective both by contact (via soil, glass, walls, mosquito nets, carpets, plant parts or animal parts) and by ingestion (bait or plant parts).

[0223] The pest-killing mixture or composition comprising the present invention may also be applied against non-crop insect pests, such as ants, termites, wasps, flies, mosquitoes, crickets, or cockroaches. For use against said non-crop pests, the pest-killing mixture or composition comprising the present invention may be used in bait compositions.

[0224] The bait used in the composition is a product that has sufficient attractiveness to induce insects, such as ants, termites, wasps, flies, mosquitoes, crickets, or cockroaches, to eat it.

[0225] Attractiveness can be manipulated by using feeding stimulants or sex pheromones. Food stimulants include, but are not limited to, animal and / or plant proteins (meat meal, fish meal or blood meal, insect parts, egg yolks), animal and / or plant-derived fats and oils, or monosaccharides, oligosaccharides or polyorganic sugars, particularly sucrose, lactose, fructose, glucose, starch, pectin, or even molasses or honey. Fresh or decaying parts of fruits, crops, plants, animals, insects or specific parts thereof can also function as feeding stimulants.

[0226] Sex pheromones are known to be more insect-specific. Certain pheromones are documented in the literature and are known to those skilled in the art.

[0227] The typical content of the active ingredient for use in bait compositions is 0.001% to 15% by weight of the active compound, preferably 0.001% to 5% by weight.

[0228] Formulations of the biocitriactive mixture according to the present invention, as aerosols (e.g., in spray cans), oil sprays, or pump sprays, are highly suitable for non-professional users for controlling pests such as flies, fleas, ticks, mosquitoes, or cockroaches. The aerosol formulation preferably comprises an active compound, a solvent, such as a lower alcohol (e.g., methanol, ethanol, propanol, butanol), a ketone (e.g., acetone, methyl ethyl ketone), a paraffinic hydrocarbon (e.g., kerosene) having a boiling range of approximately 50-250°C, dimethylformamide, N-methylpyrrolidone, dimethyl sulfoxide, an aromatic hydrocarbon, such as toluene, xylene, water, and further auxiliary agents, such as an emulsifier, such as sorbitol monooleate, oleyl ethoxylate, aliphatic alcohol ethoxylate, having 3-7 moles of ethylene oxide, an oil, such as ether oil, an ester of an intermediate fatty acid with a lower alcohol, an aromatic carbonyl compound, a stabilizer, if appropriate, such as sodium benzoate, an amphoteric surfactant, a lower epoxide, triethyl orthoformate, and, if required, a spraying agent, such as propane, butane, nitrogen, compressed air, dimethyl ether, carbon dioxide, nitrous oxide, or a mixture of these gases.

[0229] Oil spray formulations differ from aerosol formulations in that they do not use any spraying agents.

[0230] The content of the active ingredient for use in the spray composition is 0.001 to 80% by weight, preferably 0.01 to 50% by weight, and most preferably 0.01 to 15% by weight.

[0231] The pest-killing biological mixtures and compositions comprising the mixture according to the present invention can also be used in mosquito and fumigation coils, smoke cartridges, vaporizer plates or long-term vaporizers, as well as moss paper, moss pads or other non-heat-dependent vaporizer systems.

[0232] Methods of controlling insects that cause infectious diseases (e.g., malaria, dengue fever and yellow fever, lymph node filariasis, and leishmaniasis) using the biotoxic mixtures and their respective compositions according to the present invention also include surface treatment of sheds and companies, air spraying, and impregnation of curtains, tents, clothing, mosquito nets, tsetse fly traps, etc. Insecticidal compositions for application to textiles, woven fabrics, knitted products, nonwovens, netting materials, or foils and waterproof fabrics preferably comprise a mixture containing an insecticide, optionally a repellent, and at least one binder. Suitable repellents include, for example, N,N-diethyl-meth-toluamide (DEET), N,N-diethylphenylacetamide (DEPA), 1-(3-cyclohexane-1-yl-carbonyl)-2-methylpiperine, (2-hydroxymethylcyclohexyl)acetate lactone, 2-ethyl-1,3-hexanediol, indalone, methylneodecanamide (MNDA), pyrethroids not used for insect control, such as {(+ / -)-3-allyl-2-methyl-4-oxocyclopenta-2-(+)-enyl-(+)-trans-chrysanthemate (Esbiothrin), repellents derived from or identical to plant extracts, such as limonene, eugenol, (+)-eucamarol(1), (-)-1-epi-eucamarol, or crude plant extracts derived from plants, such as Eucalyptus maculata, Vitex These are rotundifolia, Cymbopogan martinii, Cymbopogan citratus (lemongrass), and Cymbopogan nartdus (citronella).

[0233] Suitable binders are selected from, for example, polymers and copolymers of aliphatic acid vinyl esters (e.g., vinyl acetate and vinyl versatate), acrylic acid and methacrylic acid esters of alcohols, e.g., butyl acrylate, 2-ethylhexyl acrylate, and methyl acrylate, monoethylene unsaturated and diethylene unsaturated hydrocarbons, e.g., styrene, and aliphatic dienes, e.g., butadiene.

[0234] The biotoxic mixture and compositions containing the same according to the present invention can be used to protect woody materials, such as wood, wooden fences, railway ties, etc., and buildings, such as companies, barns, factories, and also construction materials, furniture, leather, textiles, vinyl products, electric wires and cables, etc., from ants and / or termites, and to prevent ants and termites from damaging crops or people (for example, when pests invade companies and public facilities). The biotoxic mixture or compositions containing the mixture according to the present invention can be applied not only to the soil surface or underfloor soil to protect woody materials, but also to the surfaces of lumber, such as underfloor concrete, floor pillars, beams, plywood, furniture, etc., wood products, such as particleboard, halfboard, etc., and vinyl products, such as coated electric wires, vinyl sheets, insulation materials, such as styrene foaming agents, etc. In the case of application to ants that damage crops or people, the ant control agent of the present invention is applied to the crop or surrounding soil, or directly to ant nests, etc.

[0235] Seed treatment The pest-killing mixture or composition containing the mixture according to the present invention is also suitable for seed treatment to protect seeds from insect pests, particularly soil-dwelling insect pests, and to protect the resulting plant roots and shoots from soil pests and leaf insects.

[0236] The pest-killing mixture or composition containing the mixture according to the present invention is particularly useful for protecting seeds from soil pests, and for protecting the roots and shoots of the resulting plants from soil pests and leaf insects.

[0237] Protection of the resulting plant roots and shoots is desirable. More preferably, the resulting plant shoots are protected from burrowing and sap-sucking insects.

[0238] Accordingly, the present invention includes methods for protecting seeds from insects, particularly soil insects, and for protecting the roots and shoots of seedlings from insects, particularly soil and leaf insects, the methods comprising contacting seeds with a mixture according to the present invention before sowing and / or after pre-germination treatment. Methods for protecting plant roots and shoots are particularly preferred, methods for protecting plant shoots from burrowing and sap-sucking insects are more preferred, and methods for protecting plant shoots from aphids are most preferred. Methods for protecting plant roots and shoots from chewing and biting insects are also preferred, methods for protecting plant shoots and roots from lepidopterans and / or beetles are most preferred, and methods for protecting plant shoots and roots from rice leaf beetles are most preferred.

[0239] The term "seed" encompasses all types of seeds and plant vegetative propagates, including but not limited to true seeds, seed fragments, suckers, corms, bulbs, fruits, tubers, grains, cuttings, and severed twigs, and in preferred embodiments, it refers to true seeds.

[0240] The term "seed treatment" includes all suitable seed treatment techniques known in the art, such as seed coating, seed dusting, seed dipping, and seed pelletizing.

[0241] The present invention also includes seeds coated with or containing the pest-killing mixture according to the present invention.

[0242] The term "coated and / or containing" generally means that, while the majority of the active ingredient is on the surface of the growth product at the time of application, depending on the method of application, some of the ingredient may more or less penetrate into the growth product. If the growth product is (re)planted, it may absorb the active ingredient.

[0243] Suitable seeds include seeds of cereals, root crops, oil crops, plants, spices, and ornamental plants, such as durum wheat and other wheats, barley, oats, rye, maize (forage maize and sugar maize / sweet and field maize), soybeans, oil crops, cruciferous plants, cotton, sunflowers, bananas, rice, rapeseed, rapeseed, sugar beets, mangelwarsel, eggplant, potatoes, grasses, mycelium, turfgrasses, forage grasses, tomatoes, leeks, pumpkins / squash, cabbage, iceberg lettuce, peppers, cucumbers, melons, rapeseed seeds, melons, beans, peas, garlic, onions, carrots, and tuberous plants, such as potatoes, sugarcane, tobacco, grapes, petunias, geraniums / baby ginger, pansies, and impatiens.

[0244] In addition, the present invention may also be used to treat seeds from plants that have been resistant to the action of herbicides, fungicides, or insecticides through breeding, including genetic engineering methods.

[0245] For example, the pesticide-active mixture or composition comprising the mixture according to the present invention can be used in the treatment of plant seeds resistant to herbicides from the group consisting of sulfonylurea, imidazolinone, glufosinate-ammonium or glyphosate-isopropylammonium and similar active substances (see, for example, EP-A242236, EP-A242246) (WO92 / 00377) (EP-A257993, U.S. Patent No. 5,013,659), or in the treatment of genetically modified crops, such as cotton having the ability to produce Bacillus thuringiensis toxin (Bt toxin) that confers resistance to specific pests present in the plant (EP-A142924, EP-A193259).

[0246] Furthermore, the pesticide-causing mixtures or compositions comprising such mixtures according to the present invention may also be used to treat seeds from plants that have modified characteristics compared to existing plants and can be produced, for example, by conventional breeding methods and / or by the generation of mutants or by recombinant procedures. For example, several examples are described of recombinant crop modifications (e.g., WO92 / 11376, WO92 / 14827, WO91 / 19806) or genetically modified crops having modified fatty acid compositions (WO91 / 13972) for the purpose of modifying the starch synthesized within the plant.

[0247] The application of the active compound to the seeds is carried out by spraying or dusting the seeds before sowing and before the plants emerge.

[0248] Compositions particularly useful for seed treatment include, for example: Liquid formulation (water-coated) (SL, LS) Emulsion formulations (EW, EO, ES) Flowable formulations (SC, OD, FS) Water-dispersible granules and water-soluble granules (WG, SG) Water-dispersible powders and water-soluble powders (WP, SP, WS) Gel formulation (GF) Powder (DP, DS)

[0249] Conventional seed treatment formulations include, for example, fluid concentrates FS, liquid formulations LS, dry-treatment powders DS, water-dispersible powders WS for slurry treatment, water-soluble powders SS and emulsions ES and EC, and gel formulations GF. These formulations can be applied to seeds with or without dilution. Application to seeds is carried out before sowing, either directly to the seeds or after pre-germination treatment of the seeds.

[0250] In preferred embodiments, the FS formulation is used for seed treatment. Typically, the FS formulation may contain 1 to 800 g / l of active ingredient, 1 to 200 g / l of surfactant, 0 to 200 g / l of antifreeze, 0 to 400 g / l of binder, 0 to 200 g / l of pigment, and up to 1 liter of solvent, preferably water.

[0251] A particularly preferred FS formulation for seed treatment, comprising a compound of formula (I), compound (II), or a mixture of pesticide-active compounds according to the present invention, typically contains 0.1 to 80% by weight (1 to 800 g / l) of the active ingredient, 0.1 to 20% by weight (1 to 200 g / l) of at least one surfactant, for example, 0.05 to 5% by weight of a wetting agent and 0.5 to 15% by weight of a dispersant, and up to 20% by weight, for example, 5 to 20% of an antifreeze. The mixture contains 0-15% by weight, for example, 1-15% by weight of pigments and / or dyes; 0-40% by weight, for example, 1-40% by weight of binders (fixatives / adherents); optionally up to 5% by weight, for example, 0.1-5% by weight of thickeners; optionally 0.1-2% of defoaming agents; optionally preservatives, for example, biocides, antioxidants, etc., in amounts of, for example, 0.01-1% by weight; and up to 100% by weight of fillers / vehicles.

[0252] The seed treatment formulation also further comprises a binder and optionally further comprises a colorant. The binder can be added to improve the adhesion of the active substance to the seeds after treatment. Suitable binders are alkylene oxides, e.g., ethylene oxide or propylene oxide, polyvinyl acetate, polyvinyl alcohol, polyvinylpyrrolidone-derived homopolymers and copolymers, as well as their copolymers, ethylene-vinyl acetate copolymers, acrylic acid homopolymers and copolymers, polyethyleneamines, polyethyleneamides and polyethyleneimines, polysaccharides, e.g., cellulose, tyroses and starches, polyolefin homopolymers and copolymers, e.g., olefin / maleic anhydride copolymers, polyurethanes, polyesters, polystyrene homopolymers and copolymers.

[0253] Colorants can be optionally included in the formulation. Suitable colorants or dyes for seed treatment formulations are Rhodamin B, CIPigment Red 112, CISolvent Red 1, Pigment Blue 15:4, Pigment Blue 15:3, Pigment Blue 15:2, Pigment Blue 15:1, Pigment Blue 80, Pigment Yellow 1, Pigment Yellow 13, Pigment Red 112, Pigment Red 48:2, Pigment Red 48:1, Pigment Red 57:1, Pigment Red 53:1, Pigment Orange 43, Pigment Orange 34, Pigment Orange 5, Pigment Green 36, Pigment Green 7, Pigment White 6, Pigment Brown 25, Basic Violet 10, Basic Violet 49, Acid Red 51, Acid Red 52, Acid Red 14, Acid Blue 9, Acid Yellow 23, Basic Red 10, and Basic Red 108.

[0254] An example of a gelling agent is carrageenan (Satiagel®).

[0255] In seed treatment, the application rate of compound I is generally 0.1 g to 10 kg per 100 kg of seeds, preferably 1 g to 5 kg per 100 kg of seeds, more preferably 1 g to 1000 g per 100 kg of seeds, and particularly 1 g to 200 g per 100 kg of seeds.

[0256] Therefore, the present invention also relates to seeds containing the compound of formula (I), or a salt of the compound of formula (I) as defined herein, which is useful for agricultural purposes.

[0257] The amount of compound (I) or its salt useful for agricultural purposes generally varies from 0.1 g to 10 kg per 100 kg of seeds, preferably from 1 g to 5 kg per 100 kg of seeds, and especially from 1 g to 1000 g per 100 kg of seeds. For certain crops, such as lettuce, the rate may be higher.

[0258] Without further explanation, it is reasonable to assume that any person skilled in the art using the prior art descriptions can utilize the present invention to the fullest extent. Accordingly, the following examples should be construed as merely illustrative and not to limit the present disclosure. [Examples]

[0259] Chemical examples: Preparation of thietan-3-ol: A solution of potassium hydroxide (42.8 g, 648 mmol) in water (200 mL) was saturated with freshly prepared hydrogen sulfide gas. Hydrogen sulfide gas was prepared by adding hydrochloric acid (56.3 mL, 648 mmol) to a solution of sodium sulfide 9-hydrate (156 g, 648 mmol). Simultaneously, 2-(chloromethyl)oxirane (25.4 mL, 324 mmol) was added dropwise for 2 hours while purging the hydrogen sulfide. The reaction mixture was stirred for 16 hours with the temperature gradually raised to 60°C. After the reaction was complete, the reaction mixture was extracted three times with 200 mL of ethyl acetate. The ethyl acetate layer was concentrated under reduced pressure. The crude product was distilled under high vacuum to obtain thietan-3-ol (15 g, 166 mmol, 51% yield), which was confirmed by GC-MS and NMR. 1 H NMR(400MHz,CDCl3)δ4.87(td,J=15.3,7.6Hz,1H),3.33-3.37(m,2H),3.24-3.29(m,2H),2.64-2.67(m,1H).GC-MS-90(M).

[0260] Step 1: Preparation of ethyl 3-bromo-1-(3-chloropyridine-2-yl)-4,5-dihydro-1H-pyrazole-5-carboxylate: To a solution of acetonitrile (250 mL) and ethyl 2-(3-chloropyridine-2-yl)-5-oxopyrazolidine-3-carboxylate (25 g, 93 mmol), phosphoryl tribromide (31.9 g, 111 mmol) was added at room temperature. The reaction mixture was refluxed for 5 hours. After the reaction was complete, it was cooled to 25°C and the solvent was removed under reduced pressure. The reaction mixture was diluted with water (400 mL) and quenched with a saturated sodium bicarbonate solution. The reaction mixture was extracted twice with dichloromethane (700 mL). The combined dichloromethane layers were washed with brine and dried over anhydrous sodium sulfate. Dichloromethane was removed to obtain the crude product, which was purified by combiflash chromatography using 15% ethyl acetate in hexane. Ethyl 3-bromo-1-(3-chloropyridine-2-yl)-4,5-dihydro-1H-pyrazole-5-carboxylate was obtained in good yield (29 g, 87 mmol, yield 94%). 1 H-NMR(400MHz,DMSO-d6)δ8.13(dd,J=4.6,1.5Hz,1H),7.79-7.90(m,1H),7.00(dd,J=7.8,4.6Hz,1H),5.20(dd,J=12.0,8. 8Hz,1H),4.30(d,J=6.8Hz,0H),4.12(q,J=7.1Hz,2H),3.60(dd,J=17.6,12.0Hz,1H),3.26-3.38(m,1H),0.85-1.34(m,3H).

[0261] Step 2: Preparation of ethyl 1-(3-chloropyridine-2-yl)-3-(thietan-3-yloxy)-4,5-dihydro-1H-pyrazole-5-carboxylate: To a stirred solution of ethyl 3-bromo-1-(3-chloropyridine-2-yl)-4,5-dihydro-1H-pyrazole-5-carboxylate (32 g, 96 mmol) in toluene (320 mL), cuprous iodide (9.16 g, 48.1 mmol), 1,10-phenanthroline (12.14 g, 67.4 mmol), potassium carbonate (39.9 g, 289 mmol), and thietan-3-ol (13.01 g, 144 mmol) were added. The reaction mixture was heated under reflux temperature for 16 hours. After the reaction was complete, the resulting mixture was filtered. The filtrate was diluted with water and extracted with ethyl acetate (250 ml). The organic layer was dried over sodium sulfate and evaporated. The crude product obtained was purified by column chromatography to produce ethyl 1-(3-chloropyridine-2-yl)-3-(thiethane-3-yloxy)-4,5-dihydro-1H-pyrazole-5-carboxylate (18 g, 52.7 mmol, yield 54.7%), which was confirmed by LC-MS. LC-MS: m / z = 342.1 [M+H].

[0262] Step 3: Preparation of ethyl 1-(3-chloropyridine-2-yl)-3-(thiethane-3-yloxy)-1H-pyrazole-5-carboxylate: 16 g, 46.8 mmol of ethyl 1-(3-chloropyridine-2-yl)-3-(thiethane-3-yloxy)-4,5-dihydro-1H-pyrazole-5-carboxylate (16 g, 46.8 mmol) was stirred in dioxane (160 mL), to which DDQ (12.75 g, 56.2 mmol) was added. The reaction mixture was heated under reflux temperature for 16 hours. After the reaction was complete, the resulting mixture was filtered. The obtained filtrate was diluted with water and extracted with ethyl acetate (150 mL). The ethyl acetate layer was dried over sodium sulfate and evaporated. The obtained crude product was purified by column chromatography to obtain ethyl 1-(3-chloropyridine-2-yl)-3-(thiethane-3-yloxy)-1H-pyrazole-5-carboxylate (9 g, 26.5 mmol, yield 56.6%). 1H NMR(400MHz,DMSO-d6)δ8.51-8.53(m,1H),8.21(td,J=4.1,1.5Hz,1H),7.63(dd,J=8.1,4.7Hz,1H),6.65(t,J=2.5Hz,1H),5.42- 5.50(m,1H),4.09-4.14(m,2H),3.48(td,J=8.0,1.7Hz,2H),3.39(td,J=7.6,1.9Hz,2H),1.03-1.07(m,3H).LCMS:m / z=340[M+H].

[0263] Step 4: Preparation of 1-(3-chloropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-carboxylic acid: Ethyl 1-(3-chloropyridine-2-yl)-3-(thiethane-3-yloxy)-1H-pyrazole-5-carboxylate (1.5 g, 4.4 mmol) was stirred in tetrahydrofuran (7 mL), methanol (1 mL), and water (4 mL). Lithium hydroxide hydrate (0.4 g, 8.8 mmol) was added, and the mixture was stirred at 25°C for 2 hours. After the reaction was complete, the reaction mixture was concentrated under reduced pressure. The reaction mixture was diluted with water (5 mL) and acidified with 10% hydrochloric acid at 0°C. The precipitated solid was filtered off, washed with pentane, and dried under vacuum to obtain 1-(3-chloropyridine-2-yl)-3-(thiethane-3-yloxy)-1H-pyrazole-5-carboxylic acid (1 g, 3.2 mmol, yield 74%). 1 H-NMR(400MHz,DMSO-d6)δ13.88-13.24(1H),8.50(d,J=3.7Hz,1H),8.17(d,J=7.9Hz,1H),7.60(dd,J =7.7,4.7Hz,1H),6.56(d,J=14.1Hz,1H),5.41-5.48(m,1H),3.48(t,J=8.5Hz,2H),3.36-3.40(m,2H).

[0264] Step 5: Preparation of 6-chloro-2-(1-(3-chloropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-yl)-8-methyl-4H-benzo[d][1,3]oxazin-4-one: Ms-Cl (4.87 mL, 62.6 mmol) was dissolved in acetonitrile (50 mL), and the resulting mixture was cooled to 0°C. 1-(3-chloropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-carboxylic acid (15 g, 48.1 mmol) and pyridine (6.62 mL, 82 mmol) in acetonitrile (75 mL) were added dropwise over 5 minutes at the same temperature. A slurry was formed during the addition. The mixture was stirred at this temperature for 10 minutes. Then, 2-amino-5-chloro-3-methylbenzoic acid (8.93 g, 48.1 mmol) and pyridine (6.62 mL, 82 mmol) in acetonitrile (75 mL) were added to the reaction mixture. The reaction mixture was stirred at the same temperature for 15 minutes, and Ms-Cl (4.87 mL, 62.6 mmol) in acetonitrile (50 ml) was added dropwise over 5 minutes at the same temperature. The reaction mixture was then stirred at the same temperature for 15 minutes and at 25°C for 16 hours. After the reaction was complete, the reaction mixture was diluted with water, the precipitated solid was filtered, washed with water, and dried under vacuum to obtain 6-chloro-2-(1-(3-chloropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-yl)-8-methyl-4H-benzo[d][1,3]oxazin-4-one (17 g, 36.9 mmol, yield 77%). 1 H-NMR(400MHz,DMSO-d6)δ8.57(dd,J=4.7,1.4Hz,1H),8.27(dd,J=8.1,1.5Hz,1H),7.88(d,J=2.3Hz,1H),7.76(d,J=1.7Hz,1H),7.69(dd ,J=8.1,4.7Hz,1H),6.84(s,1H),5.48-5.56(m,1H),3.52(dd,J=9.8,7.9Hz,2H),3.40-3.45(m,2H),1.71(s,3H).LCMS:m / z=460.90[M+H]

[0265] Step 6: Preparation of N-(2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl)-1-(3-chloropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-carboxamide: A stirred solution of 6-chloro-2-(1-(3-chloropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-yl)-8-methyl-4H-benzo[d][1,3]oxazin-4-one (22 g, 47.7 mmol) in tetrahydrofuran (220 mL) was cooled to 0°C, and 2-methylpropan-2-amine (15.03 mL, 143 mmol) was added dropwise. The resulting reaction mixture was stirred at 0°C for 2 hours. After the reaction was complete, the reaction mixture was concentrated. The crude product was purified by column chromatography using 4-5% methanol / dichloromethane to produce N-(2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl)-1-(3-chloropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-carboxamide (17 g, 31.8 mmol, yield 66.7%). 1 H-NMR(400MHz,DMSO-d6)δ10.05(s,1H),8.44(dd,J=4.6,1.5Hz,1H),8.11(d d,J=8.1,1.5Hz,1H),7.61(s,1H),7.54(dd,J=8.1,4.6Hz,1H),7.43(d,J=2.0 Hz,1H),7.26(d,J=2.0Hz,1H),6.72(s,1H),5.44-5.51(m,1H),3.51-3.55(m, 2H),3.38-3.43(m,2H),2.15(s,3H),1.23-1.26(m,9H).LCMS:m / z=534[M+H].

[0266] Step 7: N-(2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl)-1-(3-chloropyridine-2-yl)-3-((1,1-dioxidethiethane-3-yl)oxy)-1H-pyrazole-5-carboxamide: A stirred solution of N-(2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl)-1-(3-chloropyridine-2-yl)-3-(thietan-3-yloxy)-1H-pyrazole-5-carboxamide (35 g, 65.5 mmol) in acetic acid (300 mL) was slowly added to the reaction mixture with hydrogen peroxide (H2O2) (20.07 mL, 196 mmol). The reaction mixture was heated to 100 °C and stirred for 3 hours. After the reaction was complete, the reaction mixture was alkalized with 15% NaOH aqueous solution. The reaction mixture was diluted with 150 mL of water, extracted with dichloromethane (2 × 250 mL), and dried over sodium sulfate. The dichloromethane layer was concentrated under reduced pressure, and the crude product was purified by combi-flash chromatography to obtain N-(2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl)-1-(3-chloropyridine-2-yl)-3-((1,1-dioxidethiethane-3-yl)oxy)-1H-pyrazole-5-carboxamide (23.05 g, 40.7 mmol, yield 62.1%). 1 H-NMR(400MHz,DMSO-d6)δ10.11(s,1H),8.45(dd,J=4.6,1.5Hz,1H),8.12(dd, J=7.9,1.6Hz,1H),7.62(s,1H),7.56(dd,J=7.9,4.8Hz,1H),7.43-7.44(m,1H) ,7.27(d,J=2.0Hz,1H),6.80(s,1H),5.29-5.34(m,1H),4.71-4.77(m,2H),4.2 9(dd,J=15.9,2.4Hz,2H),2.16-2.34(m,3H),1.25(s,9H).LCMS:m / z=566[M+H].

[0267] biology As described herein, the compounds of formula (I) and their compositions exhibit synergistic insecticidal / fungicidal activity against many pests / plant pathogenic fungi that attack important crops.

[0268] Synergistic effects can be described as interactions where the combined effect of two or more compounds is greater than the sum of the individual effects of each compound. The presence of a synergistic effect between two mixed partners (X and Y) can be calculated as a control percentage using Colby's equation (Colby, SR, 1967, *Calculating Synergistic and Antagonistic Responses in Herbicide Combinations*, Weeds, Vol. 15, pp. 20-22): Colby's formula: The expected activity for a given combination of two active compounds (a two-component composition) can be calculated as follows: E = X + Y - (XY / 100) [In the formula, E represents the expected percentage of pest inhibition for a combination of two insecticides or one insecticide and one fungicide at defined doses (e.g., x and y are equal), x is the percentage of inhibition observed against pests / diseases by compound (1) at a given dose (equal to x), and y is the percentage of inhibition observed against pests / diseases by compound (2) or (3) at a defined dose (equal to y)]. A synergistic effect exists if the observed percentage of inhibition for a combination is greater than E.

[0269] The expected activity for a given combination of three active compounds (three-component composition) can be calculated as follows: E=X+Y+Z-(XY+XZ+YZ) / 100+(XYZ) / 10000 X: Efficacy, expressed as the percentage of untreated control when active compound (1) is used at concentration a. Y: Efficacy, expressed as the percentage of the untreated control when the active compound (2) is used at concentration b. Z: Efficacy, expressed as the percentage of the untreated control when the active compound (3) is used at concentration c.

[0270] E is the efficacy when the active compounds (1), (2), and (3) are applied at doses a, b, and c.

[0271] The following biological tests demonstrate the pesticidal efficacy of the compounds, mixtures, or compositions of the present invention against important pests. However, the pest control protection provided by the compounds, mixtures, or compositions is not limited to these species. In certain cases, combinations of the compounds of the present invention with other invertebrate pest control compounds or agents have been found to exhibit similar synergistic effects against further invertebrate pests.

[0272] Biological examples: The compounds of formula (I-1) in two-component mixtures with other insecticides or fungicides of the present invention were evaluated for their insecticidal activity, as described in the following tests:

[0273] <Example A> Compounds (I-1) and mixtures thereof for Helicoverpa armigera The feed mixing method was used. In this method, when the temperature in the bioassay container was approximately 50°C, the semi-synthetic feed was mixed into the test solution, which consisted of either a single compound or a combination of each compound, and then stirred thoroughly until properly mixed, and allowed to cool for 30 minutes. The solidified feed was cut into equal pieces, and each piece was then transferred to one cell in a bioassay tray. One starved third-instar larva was released into each of these cells in the bioassay tray, and the tray was covered. The bioassay tray was maintained under laboratory conditions, at a temperature of 25°C and a relative humidity of 70%. Observations of dead, dying, and living larvae were recorded 96 hours after larval release. The percentage mortality rate was calculated by combining the dead and dying larvae and comparing the results to one of the untreated controls. The results for the compound of formula (I-1) are shown in Table A.

[0274] Surprisingly, the following combinations, as shown in the table below, reveal unexpected synergistic effects:

[0275] [Table 1] [Table 2] [Table 3] [Table 4]

[0276] <Example B> Evaluation of compounds (I-1), insecticides selected from [(II-1A)~(II-33)] or [(Z001)~(Z377)], or fungicides selected from groups A)~P), and mixtures thereof, against Spodoptera litura. The feed mixing method was used. In this method, when the temperature in the bioassay container was approximately 50°C, the semi-synthetic feed was mixed into the test solution, which consisted of either a single compound or a combination of each compound, and then stirred thoroughly until properly mixed, and allowed to cool for 30 minutes. The solidified feed was cut into equal pieces, and each piece was then transferred to one cell in a bioassay tray. One starved third-instar larva was released into each of these cells in the bioassay tray, and the tray was covered. The bioassay tray was maintained under laboratory conditions, at a temperature of 25°C and a relative humidity of 70%. Observations of dead, dying, and living larvae were recorded 96 hours after release. The percentage mortality rate was calculated by combining the dead and dying larvae and comparing the results to one of the untreated controls. The results for the compound of formula (I-1) are shown in Table B.

[0277] Surprisingly, the following combinations, as shown in the table below, reveal unexpected synergistic effects:

[0278] [Table 5] [Table 6] [Table 7] [Table 8] [Table 9]

[0279] <Example C> Compounds of formula (I-1) and fungicides selected from the insecticides [(II-1A)~(II-33)] or [(Z001)~(Z377)] or groups A)~P) against Plutella xylostella, as well as mixtures thereof. The leaf immersion method was used. In this method, the required amount of compound or combination of compounds was weighed and dissolved in the prepared test solution in a tube. The tube was vortexed to ensure proper mixing, and then diluted to the desired test concentration with 0.01% Triton-X solution. Cabbage leaves were immersed in the solution for 10 seconds, dried in the shade for 20 minutes, and then transferred to single cells in a bioassay tray. One second-instar larva was released into each cell, and the tray was covered. The bioassay tray was maintained under laboratory conditions at a temperature of 25°C and a relative humidity of 70%. Observations of dead, dying, and living larvae were recorded 72 hours after release. The percentage mortality rate was calculated by combining the dead and dying larvae and comparing the results to one of the untreated controls. The results for the compound of formula (I-1) are shown in Table C.

[0280] Surprisingly, the following combinations, shown in the table below, reveal unexpected synergistic effects:

[0281] [Table 10] [Table 11] [Table 12]

[0282] As described in the following study, the compound of formula (I-1) mixed with a biologically active compound (Bacillus thiringiensis, as an example for a biological agent) was also evaluated for its activity:

[0283] <Example D> Biological testing method for evaluating Bacillus thuringiensis against Helicoverpa armigera The leaf immersion method was used. In this method, the required amount of compound was weighed and dissolved in the prepared test solution in a tube. The tube was vortexed to ensure proper mixing, and then, for single compounds, it was diluted with 0.01% Triton-X solution, and for combinations, it was diluted with 0.01% Triton-X solution containing formulated Bt to obtain the desired test concentration. Tomato leaves were immersed in the solution for 10 seconds, dried in the shade for 20 minutes, and then transferred to single cells in a bioassay tray. One third-instar larva was released into each cell, and the tray was covered. The bioassay tray was maintained under laboratory conditions at a temperature of 25°C and a relative humidity of 70%. Observations of dead, dying, and living larvae were recorded 72 hours after release. The percentage mortality rate was calculated by combining the dead and dying larvae and comparing the results to one of the untreated controls. The results for the compound of formula (I-1) are listed in Table D.

[0284] [Table 13]

[0285] <Example E> Biological test method for evaluating Bacillus thuringiensis against Spodoptera litura The leaf immersion method was used. In this method, the required amount of compound was weighed and dissolved in the prepared test solution in a tube. The tube was vortexed to ensure proper mixing, and then, for single compounds, it was diluted with 0.01% Triton-X solution, and for combinations, it was diluted with 0.01% Triton-X solution containing formulated Bt to obtain the desired test concentration. Tomato leaves were immersed in the solution for 10 seconds, dried in the shade for 20 minutes, and then transferred to single cells in a bioassay tray. One third-instar larva was released into each cell, and the tray was covered. The bioassay tray was maintained under laboratory conditions at a temperature of 25°C and a relative humidity of 70%. Observations of dead, dying, and living larvae were recorded 72 hours after release. Percent mortality was calculated by combining dead and dying larvae and comparing the results to one of the untreated controls. The results for the compound of formula (I-1) are listed in Table E.

[0286] [Table 14]

[0287] <Example F> Biological test method for evaluating Bacillus thuringiensis against Plutella xylostella The leaf immersion method was used. The required amount of compound was weighed and dissolved in the prepared test solution in a tube. The tube was vortexed to ensure proper mixing, and then, for single compounds, it was diluted with 0.01% Triton-X solution, and for combinations, it was diluted with 0.01% Triton-X solution containing formulated Bt to obtain the desired test concentration. Cabbage leaves were immersed in the solution for 10 seconds, dried in the shade for 20 minutes, and then transferred to single cells in a bioassay tray. One second-instar larva was released into each cell, and the tray was covered. The bioassay tray was maintained under laboratory conditions at a temperature of 25°C and a relative humidity of 70%. Observations of dead, dying, and living larvae were recorded 72 hours after release. The percentage mortality rate was calculated by combining the dead and dying larvae and comparing the results to one of the untreated controls. The results for the compound of formula (I-1) are listed in Table F.

[0288] [Table 15]

[0289] As demonstrated in the table above, the mixture of compound (I-1) and Bacillus thurigiensis showed stable and unexpected synergistic insecticidal effects against the most important lepidopteran pests, as an example of a biological formulation.

[0290] The compounds of formula (I-1) in mixtures with fungicides were evaluated for their bactericidal activity as described in the following tests:

[0291] Examples of in vivo biological tests on plants (precautionary) Compounds were selected for greenhouse tests to evaluate the bactericidal activity of the following combinations against pathogens under preventive conditions:

[0292] <Example G> Compounds of formula (I-1) and mixtures thereof in relation to Alternaria solani in tomatoes A single compound or a combination of each compound was dissolved in 2% dimethyl sulfoxide / acetone, and then mixed with water containing an emulsifier up to a calibrated spray volume of 50 mL. The test solution was poured into a spray bottle for further application.

[0293] To test the preventative activity, the active compound preparation was sprayed at the stated application rate onto healthy young tomato plants grown in a greenhouse using a hollow cone nozzle inside a spray cabinet. One day after treatment, the plants showed 0.24 × 10⁻¹⁴ 6 The plants were inoculated with a spore suspension containing Alternaria solani spawn and 2% malt. The inoculated plants were then kept in a greenhouse chamber at a temperature of 22-24°C and a relative humidity of 90-95% to induce disease development.

[0294] Visual evaluation of the performance of single compounds or combinations of compounds was performed by assessing the disease severity (on a 0-100% scale) of treated plants 3, 7, 10, and 15 days after application. The effectiveness (%) of single compounds and mixtures was calculated by comparing the disease assessment in the treatment with that of one of the untreated controls. The suitability of the compounds for these plants was also evaluated by recording symptoms such as necrosis, bleaching, and growth inhibition. The results for the compound of formula (I-1) are shown in Table G.

[0295] [Table 16]

[0296] <Example H> Compounds of formula (I-1), fungicides selected from groups A) to P) and mixtures thereof against Phakopsora pachyrhizi in soybeans. A single compound or a combination of each compound was dissolved in 2% dimethyl sulfoxide / acetone, and then mixed with water containing an emulsifier up to a calibrated spray volume of 50 mL. The test solution was poured into a spray bottle for further application.

[0297] To test the prophylactic activity of the compound, the active compound preparation was sprayed at the stated application rate onto healthy young soybean plants grown in a greenhouse, using a hollow cone nozzle inside a spray cabinet. One day after treatment, the plants had 2 × 10 5 A suspension containing conidia of Phakopsora pachyrhizi was inoculated into the plants. The inoculated plants were then kept in a greenhouse chamber at a temperature of 22-24°C and a relative humidity of 80-90% to induce disease development.

[0298] Visual evaluation of the performance of individual compounds and combinations of compounds was performed by assessing the disease severity (on a 0-100% scale) of treated plants 3, 7, 10, and 15 days after application. The efficacy of each compound (percentage of control) was calculated by comparing the disease assessment in the treated plants with that of one of the untreated controls. The suitability of each compound for these plants was also evaluated by recording symptoms such as necrosis, bleaching, and growth inhibition. The results for the compound of formula (I-1) are shown in Table H.

[0299] [Table 17]

[0300] <Example I> Compounds of formula (I-1) and mixtures thereof against Pyricularia oryzae in rice. A single compound or a combination of each compound was dissolved in 2% dimethyl sulfoxide / acetone, and then mixed with water containing an emulsifier up to a calibrated spray volume of 50 mL. The test solution was poured into a spray bottle for further application.

[0301] To test the prophylactic activity of the compound, the active compound preparation was sprayed at the stated application rate onto healthy young tomato plants grown in a greenhouse, using a hollow cone nozzle inside a spray cabinet. One day after treatment, the plants had 1.4 × 10⁻⁶ 6A spore suspension containing Pyricularia oryzae spawn (in sterile water) was inoculated into the plants. The inoculated plants were then kept in a greenhouse chamber at a temperature of 22-24°C and a relative humidity of 90-95% to induce disease development.

[0302] The performance of the compound or combination of compounds was visually evaluated by assessing the disease severity (on a 0-100% scale) of the treated plants 3, 7, 10, and 15 days after application. The effectiveness (%) of single compounds and mixtures was calculated by comparing the disease assessment in the treatment with one of the untreated controls. The suitability of the compounds for these plants was also evaluated by recording symptoms such as necrosis, bleaching, and growth inhibition. The results for the compound of formula (I-1) are listed in Table I.

[0303] [Table 18]

[0304] <Example J> Compounds of formula (I-1) and mixtures thereof against Parastagonospora nodorum / Septoria nodorum / Stagnospora nodorum in wheat. A single compound or a combination of each compound was dissolved in 2% dimethyl sulfoxide / acetone, and then mixed with water containing an emulsifier up to a calibrated spray volume of 50 mL. The test solution was poured into a spray bottle for further application.

[0305] To test the prophylactic activity of the compound, the active compound preparation was sprayed at the stated application rate onto healthy young tomato plants grown in a greenhouse, using a hollow cone nozzle inside a spray cabinet. One day after treatment, the plants had 2.8 × 10⁻⁶ 6 A spore suspension containing the Stagnospora nodorum fungus was inoculated.

[0306] Next, the inoculated plants were kept in a greenhouse chamber at a temperature of 22-25°C and a relative humidity of 90-100% to induce disease development.

[0307] Visual evaluation of the performance of single compounds or combinations of compounds was performed by assessing the disease severity (on a 0-100% scale) of treated plants 3, 7, 10, and 15 days after application. The effectiveness (%) of single compounds and mixtures was calculated by comparing the disease assessment in the treatment with that of one of the untreated controls. The suitability of the compounds for these plants was also evaluated by recording symptoms such as necrosis, bleaching, and growth inhibition. The results for the compound of formula (I-1) are shown in Table J.

[0308] [Table 19]

[0309] <Example K> Compounds of formula (I-1) and mixtures thereof in relation to Erysiphe cichoracearum in cucumbers. A single compound or a combination of each compound was dissolved in 2% dimethyl sulfoxide / acetone, and then mixed with water containing an emulsifier up to a calibrated spray volume of 50 mL. The test solution was poured into a spray bottle for further application.

[0310] To test the prophylactic activity of the compound, the active compound preparation was sprayed at the stated application rate onto healthy young cucumber plants grown in a greenhouse, using a hollow cone nozzle inside a spray cabinet. One day after treatment, the plants had 2 × 10 5 A conidial suspension containing Erysiphe cichoracearum spawn was inoculated into the plants. The inoculated plants were then kept in a greenhouse chamber at a temperature of 22-24°C and a relative humidity of 50-60% to induce disease development.

[0311] The performance of each compound and each combination of compounds was visually evaluated by assessing the disease severity (on a 0-100% scale) of treated plants 3, 7, 10, and 15 days after application. The effectiveness of a single compound or combination of compounds (percentage of control) was calculated by comparing the disease assessment in the treatment with that of one of the untreated controls. The suitability of each compound for these plants was also evaluated by recording symptoms such as necrosis, bleaching, and growth inhibition. The results for the compound of formula (I-1) are shown in Table K.

[0312] [Table 20]

[0313] As demonstrated in the table above, mixtures of the compound of formula I-1 with different insecticides and fungicides not only showed surprising and unexpected synergistic insecticidal effects, but also fungicidal effects against a range of different important diseases.

[0314] While the present invention has been described with reference to certain preferred embodiments, other embodiments will become apparent to those skilled in the art by considering this specification. It will be apparent to those skilled in the art that many modifications can be made to both materials and methods without departing from the scope of the present invention.

Claims

1. A synergistic pesticide mixture comprising the following: The constituent component (1) is the toxic biological compound (I-1)N-(2-(tert-butylcarbamoyl)-4-chloro-6-methylphenyl)-1-(3-chloropyridine-2-yl)-3-((1,1-dioxidethiethane-3-yl)oxy)-1H-pyrazole-5-carboxamide, and The constituent component (2) is an insecticidal compound (II) or a fungicidal compound (III), Here, the insecticidal compound (II) is selected from the group consisting of the following: Acephate (Z027), Fipronil (Z095), Bifenthrin (Z103), Lambda-Cyhalotrin (Z111), Cypermethrin (Z113), Deltamethrin (Z119), Clothianidin (Z149), Dinotefuran (Z150), Imidaclopride (Z151), Thiamethoxam (Z154), Triflumezopyrim (Z161), Dichloromethothiaz (Z162), Flupyrim (Z163), Spinetoram (Z164), Spinosad (Z165), Abamectin (Z166), Emamectin Benzoate (Z167), Pyriproxyfen (Z174), Pymetrozine (Z188), Afidopiropen (Z190), Bacillus thuringiensis (Z195), diafenthiuron (Z197), chlorfenapir (Z203), cartap hydrochloride (Z207), tolfenpyrad (Z238), indoxacarb (Z240), metaflumizone (Z241), 2-[3-(ethanesulfonyl)pyridine-2-yl]-5-[trifluoro(methanesulfonyl)]-1,3-benzoxazole (oxazosulfyl) (Z243), spirotetramato (Z247), flonicamide (Z272), broflanilide (Z273), fluxamethamide (Z274), isocycloseram (Z275), flometoquin (Z292), pyridaryl (Z299), zimphropyridaz (Z317), and ticlopyrazoflor (Z318), The fungicidal compound (III) is selected from the group consisting of the following: (B005) Fluopyram, (B007) Fluxapyroxad, (C003) Azoxystrobin, (C017) Pyraclostrobin, (D007) Thiophanate-methyl, (F002) Isothianil, (F003) Probenazole, (L003) Metalaxyl, and (M001) Fludioxonil A synergistic mixture of harmful organisms.

2. The synergistic pest-killing mixture further comprises agriculturally acceptable auxiliaries, solvents, carriers, surfactants, or fillers. The synergistic pesticide mixture according to claim 1.

3. The weight ratio of component (1) and component (2) is between 1000:1 and 1:1000. The synergistic pesticide mixture according to claim 1.

4. The weight ratio of component (1) and component (2) is between 100:1 and 1:

100. The synergistic pesticide mixture according to claim 1.

5. A method for controlling insects, mites, nematodes, and plant pathogenic fungi, comprising contacting the insects, mites, nematodes, plant pathogenic fungi, or their food sources, habitats, breeding grounds, or habitats with an effective amount of the synergistic pesticide active mixture described in claim 1, method.

6. A method for protecting plants from attack or parasitism by insects, mites, nematodes, or plant pathogenic fungi, comprising contacting the plant, or the soil or water in which the plant is growing, with an effective amount of the synergistic pesticide mixture described in claim 1, method.

7. The synergistic pest-killing mixture described in claim 1 is contained in an amount of 0.1 g to 10 kg per 100 kg of seeds. seed.

8. A method for protecting plant propagation material, comprising contacting the plant propagation material with a synergistic pesticide active mixture according to claim 1 in an effective amount for killing pests, method.

9. A synergistic pest-killing mixture according to claim 1 for protecting agricultural and / or horticultural crops from pests selected from lepidopteran insects, beetles, flies and mosquitoes, thrips, termites, bugs, aphids, leafhoppers, whiteflies, scale insects, cicadas, ants, bees, wasps, sawflies, crickets, grasshoppers, locusts, and arachnids, use.

10. A synergistic pesticide mixture according to claim 1 for protecting crops and / or horticultural crops from diseases caused by insects, mites, nematodes, or plant pathogenic fungi, use.

11. A synergistic pesticide mixture according to claim 1 for treating seeds, seeds of transgenic plants and transgenic plants, use.

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