Plant disease control composition, formulation and plant disease control method

Abstract

A plant disease control composition that contains tebufloquin and pesticide(s) other than tebufloquin as active ingredients, wherein the pesticide(s) include at least one selected from the group consisting of pyraclostrobin, picoxystrobin, fluoxastrobin, mandestrobin, trifloxystrobin, azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simeconazole, mefentrifluconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, penflufen, inpyrfluxam, fluindapyr, pyraziflumid, penthiopyrad, fluopyram, pyridachlometyl, pyroquilon and ipflufenoquin.

Description

Plant disease control composition, formulation, and plant disease control method

[0001] The present disclosure relates to plant disease control compositions, formulations, and methods for controlling plant diseases.

[0002] Rice blast, caused by the rice blast fungus Pyricularia oryzae, is the most devastating disease in paddy rice cultivation, and many fungicidal compound control agents have been reported to date. Most of these are intended for preventative use, treating before the onset of rice blast. Many strains of rice blast resistant to existing fungicidal compounds have emerged, and an increasing number of fields are unable to achieve sufficient control with a single fungicidal component (Non-Patent Document 1).

[0003] Several technologies have been proposed for the use of fungicides and other fungicide compounds (e.g., Patent Documents 1 and 2). It has also been shown that a mixture of a diamine derivative having an oxycarbonyl group with a halogen-substituted hydrocarbon and another fungicide compound containing tebufloquine is active against plant diseases including rice blast (Patent Document 3). It has also been shown that a mixture of an amide compound and another fungicide compound containing tebufloquine is active against Botrytis cinerea (Patent Document 4). Furthermore, it has been shown that a mixture of tebufloquine and a fungicide compound is active against cucumber powdery mildew (Patent Document 5).

[0004] Patent Document 1: JP 2003-55114 A Patent Document 2: WO 2004 / 039156 A Patent Document 3: WO 2006 / 106811 A Patent Document 4: JP 2011-201858 A Patent Document 5: JP 2007-112760 A

[0005] Non-patent document 1: Latest trends in research on drug-resistant bacteria and strengthening countermeasures, Journal of the Pesticide Science Society of Japan, Vol. 39, No. 1, pp. 53-57, 2014

[0006] In light of the above situation, a technology for controlling plant diseases by mixing fungicides with different modes of action is desired as a measure to prevent the emergence of further fungicide-resistant bacteria.

[0007] The problem to be solved by one embodiment of the present disclosure is to provide a plant disease control composition that exhibits superior plant disease control effect compared to a plant disease control composition containing tebufloquine alone as an active ingredient. The problem to be solved by another embodiment of the present disclosure is to provide a formulation using the plant disease control composition and a plant disease control method.

[0008] The present inventors have discovered that tebufloquine and other specific fungicides exhibit a synergistic plant disease control effect, and have completed the present invention.

[0009] That is, specific means for solving the problems include the following aspects: (1) A fungicide containing tebufloquine and a fungicide other than tebufloquine as an active ingredient, wherein the fungicide is selected from the group consisting of pyraclostrobin, picoxystrobin, fluoxastrobin, mandestrobin, trifloxystrobin, azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, fluthriaf ... a plant disease control composition comprising at least one selected from the group consisting of fluconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simeconazole, mefentrifluconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, penflufen, impilfluxam, fluindapyr, pyraziflumid, penthiopyrad, fluopyram, pyridaclomethyl, pyroquilon, and ipflufenoquin. (2) The plant disease control composition according to (1), wherein the fungicide comprises at least one fungicide selected from the group consisting of pyraclostrobin, picoxystrobin, fluoxastrobin, mandestrobin, trifloxystrobin, prothioconazole, mefentrifluconazole, cyproconazole, difenoconazole, hexaconazole, propiconazole, tebuconazole, penflufen, impirfluxam, pyraziflumid, pyroquilon, and ipflufenoquin. (3) The plant disease control composition according to (1) or (2), wherein the plant disease is rice blast. (4) A formulation comprising the plant disease control composition according to any one of (1) to (3). (5) The formulation according to (4), which is selected from wettable powders, emulsifiable concentrates, flowable formulations, water dispersible granules, dry flowable formulations, dusts, DL dusts, FD dusts, microcapsules, granules, dust granules, jumbo granules, pack formulations, and aerosol formulations. (6) A method for controlling plant diseases, which comprises applying the plant disease control composition according to any one of (1) to (3) to a plant disease. (7) The method for controlling plant diseases according to (6), wherein the plant disease is rice blast.(8) The plant disease control method according to (6) or (7), wherein the application includes at least one treatment of foliage spraying and seedling box treatment.

[0010] According to one embodiment of the present disclosure, there is provided a plant disease control composition that exhibits superior plant disease control effect compared to a plant disease control composition containing tebufloquine alone as an active ingredient. According to another embodiment of the present disclosure, there are provided a formulation using the plant disease control composition and a plant disease control method.

[0011] Hereinafter, embodiments of the present disclosure will be described. Note that these descriptions and examples are provided only for the purpose of illustrating embodiments according to the present disclosure and are not intended to limit the scope of the present disclosure.

[0012] In this specification, the term "to" indicating a numerical range is used to mean that the numerical values ​​before and after it are included as the upper and lower limits. In the numerical ranges described in stages in this specification, the upper or lower limit value described in one numerical range may be replaced with the upper or lower limit value of another numerical range described in stages. Furthermore, in the numerical ranges described in this specification, the upper or lower limit value of that numerical range may be replaced with a value shown in the examples.

[0013] In this specification, the amount of each component in a target object means the total content or amount of the multiple substances present in the target object, unless otherwise specified, when multiple substances corresponding to each component are present in the target object.

[0014] One embodiment of the present disclosure relates to a plant disease control composition containing tebufloquine and a specific fungicide other than tebufloquine as an active ingredient.

[0015] The mechanism by which the plant disease control composition according to the present disclosure exerts its effects is not entirely clear, but is presumed to be as follows. The plant disease control composition according to the present disclosure applies tebufloquine, a fungicide that may not be sufficiently effective against plant diseases when used alone, in combination with a specific fungicide having a different mode of action from tebufloquine. Application of the plant disease composition according to the present disclosure produces a synergistic plant disease control effect based on the fungicidal action of tebufloquine and the fungicidal action of the specific fungicide having a different mode of action, thereby enabling efficient control of plant diseases such as rice blast. Furthermore, the plant disease control composition according to the present disclosure can reduce the risk of the emergence of resistant bacteria.

[0016] The plant disease control composition according to the present disclosure can greatly contribute to the stabilization of agricultural production.

[0017] Fungicides other than tebufloquine according to the present disclosure include pyraclostrobin, picoxystrobin, fluoxastrobin, mandestrobin, trifloxystrobin, azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, myclobutanil, and penconazole. The fungicide contains at least one fungicide selected from the group consisting of tetraconazole, propiconazole, prothioconazole, simeconazole, mefentrifluconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, penflufen, impirfluxam, fluindapyr, pyraziflumid, penthiopyrad, fluopyram, pyridaclomethyl, pyroquilon, and ipflufenoquin (hereinafter, these are also collectively referred to as "specific fungicides other than tebufloquine" or "fungicides to be combined with tebufloquine").

[0018] Pyraclostrobin, picoxystrobin, fluoxastrobin, mandestrobin, and trifloxystrobin are classified as strobilurin fungicides.

[0019] Azaconazole, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, penconazole, propiconazole, prothioconazole, simeconazole, mefentrifluconazole, tebuconazole, tetraconazole, triticonazole, myclobutanil, bitertanol, flusilazole, flutriafol, triadimefon, and triadimenol are classified as fungicides with sterol demethylase inhibitory activity.

[0020] Penflufen, inpirfluxam, fluindapyr, pyraziflumid, penthiopyrad, and fluopyram are classified as fungicides with succinate dehydrogenase inhibitory activity.

[0021] Preferred fungicides other than tebufloquine (i.e., fungicides to be combined with tebufloquine) include pyraclostrobin, picoxystrobin, fluoxastrobin, mandestrobin, trifloxystrobin, cyproconazole, difenoconazole, hexaconazole, propiconazole, prothioconazole, mefentrifluconazole, tebuconazole, penflufen, impirfluxam, pyraziflumid, pyroquilon, and ipflufenoquin.

[0022] In the plant disease control composition according to the present disclosure, when the fungicide to be combined with tebufloquine is a strobilurin fungicide, the mixing ratio by mass of tebufloquine to the fungicide to be combined with tebufloquine is preferably 1:0.0001 to 10. When the fungicide to be combined with tebufloquine is a fungicide with sterol demethylase inhibitory activity, the mixing ratio by mass of tebufloquine to the fungicide to be combined with tebufloquine is preferably 1:0.05 to 2 ... Furthermore, when the fungicide to be combined with tebufloquine is a fungicide with succinate dehydrogenase inhibitory activity, the mixing ratio by mass of tebufloquine to the fungicide to be combined with tebufloquine is preferably 1:0.05 to 20.

[0023] More preferably, the mass ratio of tebufloquine to fungicide to be combined with tebufloquine is 1:0.0005 to 2:0 when the fungicide to be combined with tebufloquine is pyraclostrobin, picoxystrobin, fluoxastrobin, mandestrobin, or trifloxystrobin, or is 0.1 to 20:0 when the fungicide to be combined with tebufloquine is mefentrifluconazole, propiconazole, or difenoconazole, or is tebuconazole, hexaconazole, In the case of cyproconazole and simeconazole, it is 0.1 to 5; when the fungicide to be combined with tebufloquin is penflufen, impirfluxam, penthiopyrad or pyroquilon, it is 0.1 to 4; when the fungicide to be combined with tebufloquin is prothioconazole, it is 0.05 to 10; when the fungicide to be combined with tebufloquin is pyraziflumid, it is 0.1 to 10; and when the fungicide to be combined with tebufloquin is ipflufenoquin, it is 0.0001 to 2.

[0024] In the plant disease control composition according to the present disclosure, the total content of tebufloquine and specific fungicides other than tebufloquine in the plant disease control composition is not limited, but the total content (parts by mass) can be appropriately set within the range of 0.01 to 90 parts by mass per 100 parts by mass of the plant disease control composition, preferably within the range of 0.1 to 50 parts by mass per 100 parts by mass of the plant disease control composition.

[0025] Examples of plant pathogens that can be controlled by the plant disease control composition according to the present disclosure include, but are not limited to, fungi, bacteria, viruses, etc. Examples of fungi include plant pathogenic fungi, examples of bacteria include plant pathogenic bacteria, and examples of viruses include plant pathogenic viruses.

[0026] Examples of plant pathogenic fungi include Alternaria alternata, Alternaria kikutiana, Botrytis cinerea, Cochliobolus miyabeanus, Colletotrichum atramentarium, Colletotrichum lagenarium, Fusarium oxysporum f. sp. cucumerinum, Fusarium oxysporum f. sp. cucumerinum, and Fusarium oxysporum f. sp. lycopersici), Gibberella fujikuroi, Glomerella cingulata, Pyricularia oryzae, Rhizoctonia solani, Sclerotinia minor, Verticillium albo-atrum, Puccinia recondita, Erysiphe graminis, Phytophthora infestans), cucumber downy mildew (Pseudoperonospora cubensis), cucumber powdery mildew (Sphaerotheca fuliginea), rice seedling damping-off (Pythium graminicola), tomato ring spot (Alternaria solani), vegetable sclerotinia sclerotiorum, apple scab (Venturia inaequalis), peach brown rot (Monilinia fructicola), strawberry anthracnose (Colletotrichum gloeosporioides), soybean purple spot (Cercospora kikuchii), sugar beetExamples include brown spot fungus (Cercospora beticola), wheat leaf spot fungus (Leptosphaeria nodorum), wheat powdery mildew fungus (Blumeria graminis), and rice sheath blight fungus (Thanatephorus cucumeris (Frank) Donk).

[0027] Among the above-mentioned plant pathogenic fungi, preferred plant pathogenic fungi that are subject to particularly good control effects by the plant disease control composition according to the present disclosure include Helminthosporium oryzae, Gibberella oryzae, Magnaporthe grisea, Magnaporthe oryzae, Magnaporthe oryzae, and Rice sheath blight, and more preferred plant pathogenic fungi include Magnaporthe grisea.

[0028] Examples of plant pathogenic bacteria include bacteria of the genera Pseudomonas, Erwinia, Pectobacterium, Xanthomonas, Burkholderia, Streptomyces, Ralstonia, Clavibacter, Rhizomonas, Agrobacterium, Bacillus, Clostridium, Curtobacterium, Pantoea, Acidovorax, Arthrobacter, and Rhodococcus.

[0029] Further, examples of plant pathogenic viruses include soil-borne wheat mosaic virus, soybean mosaic virus, alfalfa mosaic virus, potato leaf roll virus, cucumber mosaic virus, and tobacco mosaic virus.

[0030] When the plant disease control composition according to the present disclosure is used as a formulation, the plant disease control composition according to the present disclosure may be used as is.

[0031] Furthermore, formulations containing the plant disease control composition according to the present disclosure can be made into any formulation form according to conventional methods, such as wettable powders, emulsifiable concentrates, flowable formulations, water dispersible granules, dry flowable formulations, dusts, DL dusts, FD dusts, or microcapsules.

[0032] The formulation is preferably an agrochemical formulation for use as a pesticide.

[0033] Here, DL powder refers to a formulation that suppresses scattering, with an average particle size of 20 μm or more and 20% or less of particles with a particle size of 10 μm or less, and FD powder refers to a formulation that utilizes scattering, with an average particle size of 5 μm or less.

[0034] The plant disease control composition according to the present disclosure can be used in all formulations, such as granules, powders, jumbo granules, packs, and aerosols, to be used in rice paddies and in water in seedling boxes.

[0035] These formulations can be manufactured by adding agriculturally and horticulturally acceptable additives as needed. Examples of agriculturally and horticulturally acceptable additives include carriers, surfactants, wetting agents, adhesives, thickeners, binders, antifreeze agents, colorants, and adjuvants. Examples of carriers include solid carriers, liquid carriers, and gaseous carriers. Agricultural chemical formulations can be manufactured using these additives by common manufacturing methods.

[0036] Examples of solid carriers include fine powders or granules of clays (such as clay, karyon, diatomaceous earth, bentonite, and acid clay), synthetic hydrous silicon dioxide, talc, perlite, vermiculite, pumice, and other inorganic minerals (such as sericite, quartz, sulfur, activated carbon, calcium carbonate, hydrated silica, and titanium oxide); starch, lactose, synthetic polymers such as vinyl chloride polymers and polyurethane; and plant-derived materials such as wood flour.

[0037] Examples of liquid carriers include alcohols (methanol, ethanol, isopropanol, polyethylene glycol, propylene glycol, dipropylene glycol, tripropylene glycol, glycerin, etc.), ketones (acetone, methyl ethyl ketone, etc.), aromatic hydrocarbons (benzyl alcohol, benzene, toluene, xylene, ethylbenzene, methylnaphthalene, etc.), aliphatic hydrocarbons (paraffin, n-hexane, cyclohexane, etc.), and the like. hexane, kerosene, kerosene, etc.), ethers (diethylene glycol monoethyl ether, diethylene glycol monomethyl ether, diisopropyl ether, diethyl ether, dioxane, tetrahydrofuran, etc.), esters (propylene carbonate, ethyl acetate, butyl acetate, benzyl benzoate, isopropyl myristate, fatty acid esters of propylene glycol, etc.), nitriles (acetonitrile, isobutyronitrile, etc.), amides (dimethylformamide, dimethylacetamide, N-methylpyrrolidone, etc.), halogenated hydrocarbons (dichloromethane, trichloroethane, carbon tetrachloride, etc.), animal and vegetable oils such as soybean oil and cottonseed oil, dimethyl sulfoxide, silicone oil, higher fatty acids, glycerol formal, and water.

[0038] Examples of gaseous carriers include LPG, air, nitrogen, carbon dioxide, and dimethyl ether.

[0039] The content of the carrier used in the plant disease control composition according to the present disclosure is usually 5% by mass to 99.9% by mass, and preferably 10% by mass to 98% by mass, in the plant disease control composition.

[0040] Surfactants are used for various purposes, such as emulsification, dispersion, penetration, and disintegration. The surfactants that can be used in the plant disease control composition according to the present disclosure are not particularly limited as long as they are used in conventional pesticides, and any surfactant, such as anionic surfactants, nonionic surfactants, cationic surfactants, or zwitterionic surfactants, can be used. Furthermore, these surfactants can be used alone or in combination of two or more.

[0041] Examples of anionic surfactants include alkyl phosphate ester salts, alkyl sulfate ester salts, polyoxyalkylene alkyl ether phosphate ester salts, polyoxyethylene alkyl ether sulfate ester salts, alkylaryl phosphate ester salts, alkylaryl sulfate ester salts, polyoxyalkylene alkylaryl ether phosphate ester salts, polyoxyalkylene alkylaryl ether sulfate ester salts, alkylphenol phosphate salts, alkylphenol sulfate salts, alkylphenol sulfate ester salts, polyoxyalkylene alkylphenol phosphate salts, polyoxyalkylene alkylphenol phosphate salts, polyoxyalkylene alkylphenol sulfate salts, polyoxyalkylene alkylphenol sulfate ester salts, polyoxyalkylene alkylphenol sulfate ester salts, salts, styrylphenol phosphates, styrylphenol phosphate ester salts, styrylphenol sulfates, styrylphenol sulfate ester salts, polyoxyalkylene styrylphenol phosphates, polyoxyalkylene styrylphenol phosphate ester salts, polyoxyalkylene styrylphenol sulfates, polyoxyalkylene styrylphenol sulfate ester salts, distyrylphenol phosphates, distyrylphenol phosphate ester salts, distyrylphenol sulfates, distyrylphenol sulfate ester salts, polyoxyalkylenedistyrylphenol phosphates, polyoxyalkylenedistyrylphenol phosphate ester salts, polyoxyalkylenedistyrylphenol sulfates, polyoxyalkylenedistyrylphenol sulfate ester salts, tristyrylphenol tristyrylphenol phosphate, tristyrylphenol phosphate ester salt, tristyrylphenol sulfate, tristyrylphenol sulfate ester salt, polyoxyalkylene tristyrylphenol phosphate, polyoxyalkylene tristyrylphenol phosphate ester salt, polyoxyalkylene tristyrylphenol sulfate, polyoxyalkylene tristyrylphenol sulfate ester salt, alkyl succinate sulfonate, dialkyl succinate sulfonate, and polyoxyalkylene dialkyl succinate sulfonate.

[0042] Examples of nonionic surfactants include aliphatic alcohol alkylene oxide adducts, polyalkyleneoxy fatty acid esters, sorbitan surfactants or their alkylene oxide adducts, polyglycerin fatty acid esters, alkyl polysaccharide surfactants, sucroglycerides, polyoxyalkylene alkyl ethers, polyoxyethylene alkyl ethers, polyoxyalkylene alkylaryl ethers, polyoxyalkylene alkylphenol ethers, polyoxyalkylene styrylphenol ethers, polyoxyalkylenedistyrylphenol ethers, and polyoxyalkylene tristyrylphenol ethers.

[0043] Examples of the cationic surfactant include aliphatic tertiary amines or salts thereof, aliphatic tertiary amine-aliphatic amine alkylene oxide adducts or salts thereof, and aliphatic quaternary amine salts.

[0044] Examples of amphoteric surfactants include amino acid amphoteric surfactants such as sodium laurylaminopropionate, carboxylate amphoteric surfactants such as lauryl dimethyl betaine, stearyl dimethyl betaine, and lauryl dihydroxyethyl betaine, as well as sulfate ester salt amphoteric surfactants, sulfonate salt amphoteric surfactants, and phosphate ester salt amphoteric surfactants.

[0045] The amount of surfactant used in the plant disease control composition according to the present disclosure is usually preferably 0.01% by mass to 30% by mass, and more preferably 0.05% by mass to 20% by mass, in the plant disease control composition.

[0046] Examples of wetting agents include polyoxyethylene alkylphenyl ether, sodium alkylbenzenesulfonate, dioctyl sulfosuccinate, sodium alkylnaphthalenesulfonate, sodium alkyl sulfate, sodium alkylnaphthalenesulfonate, sodium alkylbenzenesulfonate, sodium alkylsulfosuccinate, polyoxyethylene alkylaryl ether, sodium alkylnaphthalenesulfonate, and polyoxyethylene nonylphenyl ether.

[0047] Examples of the adhesive include polyacrylates, polyoxyethylene, wax, polyvinyl alkyl ethers, formalin condensates of alkylphenols, starch phosphate esters, synthetic resin emulsions, starches, resin powders, water-swellable polymeric substances, and paraffin.

[0048] The thickener is not particularly limited as long as it is one that is normally used in pesticide formulations, and examples thereof include minerals such as white carbon, aluminosilicates, bentonite, montmorillonite, hectorite, and attapulgite; and polymer thickeners such as gum arabic, gum tragacanth, xanthan gum, guar gum, roasted bean gum, casein, alginic acid, cellulose-based polysaccharides, ethyl cellulose, polyvinyl alcohol, carboxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, and carboxymethyl cellulose.

[0049] The application amount of the plant disease control composition according to the present disclosure is not limited, but the application amount can be appropriately determined depending on factors such as the weather, environmental conditions, cultivation conditions, growth state, application time, application method, and disease severity in the target area for plant disease control. The application amount of an effective plant disease control composition is preferably 0.01 g to 10 kg per 10 ares, more preferably 1 g to 5 kg per 10 ares.

[0050] The plant disease control composition according to the present disclosure can be used during the cultivation period of all crops for which pesticides are typically used, i.e., at any stage from before sowing to the germination period, seedling raising period, vegetative growth period, and before harvest. A preferred method of using the plant disease control composition according to the present disclosure is during the rice cultivation period, at any stage from after germination to the seedling raising period, field cultivation, and before harvest. A more preferred method of use is from the seedling raising period to before harvest.

[0051] Examples of applications of the plant disease control composition according to the present disclosure include foliage spray treatment on individual plants, seedling box treatment, side-stripe application using a rice transplanter, surface application to paddy field water, soil surface spray treatment, soil incorporation after soil surface spray treatment, soil injection treatment, soil incorporation after soil injection treatment, soil drench treatment, soil incorporation after soil drench treatment, spray treatment on plant seeds, smear treatment on plant seeds, application by immersion treatment of plant seeds, application as a dressing on plant seeds, mixing with plant seeds, fertilizer incorporation, etc. Although plant diseases can be controlled by these applications, more preferred methods of use are foliage spray treatment and seedling box treatment.

[0052] The plant disease control composition according to the present disclosure exhibits sufficient efficacy against plant diseases in any plant disease control method by application.

[0053] The plant disease control composition according to the present disclosure can also be applied in combination with a pest control agent such as an insecticide, acaricide, or herbicide. The plant disease control composition according to the present disclosure and the pest control agent can also be applied separately with a time lag.

[0054] Examples of the above insecticides include acephate, dichlorvos, EPN, fenitrothion, fenamifos, prothiofos, profenofos, pyraclofos, chlorpyrifos-methyl, chlorfenvinphos, and the like. hos), demeton, ethion, malathion, coumaphos, isoxathion, fenthion, diazinon, thiodicarb, aldicarb, oxamyl, propoxur, carbaryl, fenobucarb ( fenobucarb, ethiofencarb, fenothiocarb, pirimicarb, carbofuran, carbosulfan, furathiocarb, hyquincarb, alanycarb, methomyl, benfuracarb rb), cartap, thiocyclam, bensultap, dicofol, tetradifon, acrinathrin, bifenthrin, cycloprothrin, cyfluthrin, dimefluthrin, empenthrin rin), fenfluthrin, fenpropathrin, imiprothrin, metofluthrin, permethrin, phenothrin, resmethrin,Tefluthrin, tetramethrin, tralomethrin, transfluthrin, cypermethrin, deltamethrin, cyhalothrin, fenvalerate, fluvalinate, etofenprox, flufenprox, half Halfenprox, silafluofen, cyromazine, diflubenzuron, teflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, penfluron, triflumuron lumuron, chlorfluazuron, diafenthiuron, methoprene, fenoxycarb, pyriproxyfen, halofenozide, tebufenozide, methoxyfenozide, chromafenozide, dicyclanil, buprofezin (buprofezin), hexythiazox (hexythiazox), amitraz (amitraz), chlordimeform (chlordimeform), pyridaben (pyridaben), fenpyroximate (fenpyroximate), flufenerim (flufenerim), pyrimidifen (pyrimidifen), tebufenpyrad (tebufenpyrad), tolfenpyrad (tolfenpyrad), fluacrypyrim (fluacrypyrim), acequinocyl (acequinocyl),Cyflumetofen, flubendiamide, ethiprole, fipronil, etoxazole, imidacloprid, nitenpyram, clothianidin, acetamiprid, dinotefuran uran), thiacloprid, thiamethoxam, pymetrozine, bifenazate, spirodiclofen, spiromesifen, flonicamid, chlorfenapyr, pyriproxyfen ), indoxacarb, pyridalyl, spinosad, avermectin, milbemycin, azadirachtin, nicotine, rotenone, BT bacteria, BT protein, insect pathogenic virus, emamectin benzoate, spinetoram, pyrifluquinazon quinazon), chlorantraniliprole, cyantraniliprole, cyenopyrafen, spirotetramat, lepimectin, metaflumizone, pyrafluprole, pyriprole, dimefluthrin, fenazaflor (fenazaflor), hydramethylnon, triazamate, afidopyropene, and flupyrimin.

[0055] Examples of the acaricides include bromopropylate, tetradifon, propargite, amitraz, fenothiocarb, hexythiazox, and fenbutatin oxide. oxide), dienochlor, fenpyroximate, tebufenpyrad, pyridaben, pyrimidifen, clofentezine, etoxazole, halfenprox, milbemectin, and ashes Examples of antihistamines include acequinocyl, bifenazate, fluacrypyrim, spirodiclofen, spiromesifen, chlorfenapyr, avermectin, cyenopyrafen, and cyflumetofen.

[0056] Examples of the herbicides include phenoxy acid compounds such as cyhalofop-butyl and 2,4-D; carbamate compounds such as esprocarb and desmedipham; acid amide compounds such as alachlor and metolachlor; urea compounds such as diuron and tebuthiuron; Examples of the compound include sulfonylurea compounds such as halosulfuron-methyl and flazasulfuron; pyrimidyloxybenzoic acid compounds such as pyriminobac-methyl; and amino acid compounds such as glyphosate, bialaphos, glufosinate, and glufosinate salts such as glufosinate ammonium.

[0057] The plant disease control composition according to the present disclosure can be applied by mixing with a plant growth regulator or a fertilizer. Alternatively, the plant disease control composition according to the present disclosure and the plant growth regulator or fertilizer can be applied separately with a time lag.

[0058] Examples of the plant growth regulator include ethylene agents such as ethephon; auxin agents such as indolebutyric acid and ethychlozate; cytokinins; gibberellins; auxin antagonists; dwarfing agents; and antitranspiration agents.

[0059] Examples of the above fertilizers include nitrogenous fertilizers such as urea, ammonium nitrate, magnesium ammonium nitrate, and ammonium chloride; phosphate fertilizers such as calcium superphosphate, ammonium phosphate, magnesium superphosphate, and magnesium phosphate; potassium fertilizers such as potassium chloride, potassium bicarbonate, potassium magnesium nitrate, potassium nitrate, and potassium sodium nitrate; manganese fertilizers such as manganese sulfate and magnesium manganese nitrate; and boron fertilizers such as boric acid and borates.

[0060] Hereinafter, the present disclosure will be specifically explained using formulation examples and test examples, but the present disclosure is not limited to these formulation examples and test examples.

[0061] (Formulation Example 1) Wettable powder 20% by mass of tebufloquine, 4% by mass of fluoxastrobin, 56% by mass of clay, 2% by mass of white carbon, 13% by mass of diatomaceous earth, 4% by mass of calcium lignosulfonate, and 1% by mass of sodium lauryl sulfate were uniformly mixed and ground to obtain a wettable powder.

[0062] (Formulation Example 2) Water Dispersible Granules 10% by mass of tebufloquine, 10% by mass of tebuconazole, 70% by mass of clay, 5% by mass of dextrin, 4% by mass of alkyl maleic acid copolymer, and 1% by mass of sodium lauryl sulfate were uniformly mixed and ground, water was added, the mixture was kneaded well, and the mixture was granulated and dried to obtain a water dispersible granule.

[0063] (Formulation Example 3) Flowable 10% by mass of tebufloquine, 20% by mass of cyproconazole, 5% by mass of polyoxyethylene polystyrylphenyl ether sulfate, 6% by mass of propylene glycol, 1% by mass of bentonite, 0.05% by mass of a silicone antifoaming agent (trade name: PRONAL EX-300, Toho Chemical Industry Co., Ltd.), and 0.02% by mass of an antifungal agent (trade name: ADDAC 827, K.I. Kasei Co., Ltd.) were mixed, and then an appropriate amount of water was added, followed by pulverization in a wet pulverizer. Subsequently, 3% by mass of a 1% aqueous solution of xanthan gum and the remaining water were added to make 100% by mass, to obtain a flowable.

[0064] (Formulation Example 4) Emulsifiable concentrate 1% by mass of tebufloquine, 10% by mass of impirfluxam, 20% by mass of N,N-dimethylformamide, 59% by mass of an aromatic solvent (trade name: T-SOL 150, ENEOS Corporation), and 10% by mass of polyoxyethylene alkylaryl ether were uniformly mixed and dissolved to obtain an emulsifiable concentrate.

[0065] (Formulation Example 5) Dry flowable preparation 10% by weight of tebufloquine, 10% by weight of pyraziflumid, 65% by weight of kaolin clay, 5% by weight of dextrin, 5% by weight of alkyl maleic acid copolymer, and 5% by weight of sodium lauryl sulfate were uniformly mixed and ground, water was added, the mixture was thoroughly kneaded, and the mixture was granulated and dried to obtain a dry flowable preparation.

[0066] (Formulation Example 6) Dust 0.5% by mass of tebufloquine, 5.0% by mass of pyroquilon, 57.5% by mass of clay, 36% by mass of talc, and 1% by mass of calcium stearate were uniformly mixed to obtain a dust.

[0067] (Formulation Example 7) DL Powder 10% by mass of tebufloquine, 1% by mass of ipflufenoquine, 96.5% by mass of DL clay (trade name: Showa DL Clay, Showa KDE Co., Ltd.), 2% by mass of white carbon, and 0.5% by mass of light liquid paraffin were uniformly mixed to obtain DL powder.

[0068] Test Example 1: Preventive spray treatment against rice blast. Using the test solution, an aqueous acetone solution (plant disease control composition) prepared as follows was used. Control titers and theoretical values ​​were calculated, and the results are shown in Tables 1 to 18. Tebufloquine and each of the fungicides listed in Tables 1 to 18 were dissolved in acetone. This acetone solution was diluted with water to the concentrations listed in Tables 1 to 18, and a 1 / 1,000 volume of a wetting agent (Neoestellin, manufactured by Kumiai Chemical Industry Co., Ltd.) was added to prepare a spray solution. Eight to ten rice seeds (variety: Jikkoku) were planted in small pots with a diameter of 3 cm and grown in cultivation soil in a greenhouse. 2 mL of the spray solution prepared as described above was sprayed on seedlings at the two-leaf or three-leaf stage and allowed to dry naturally.

[0069] On the other hand, 1 × 10 conidia of rice blast (Pyricularia oryzae) cultured on an agar medium were added. ５ ~5 x 10 ５ The rice blast conidia were suspended at a concentration of 1000 conidia / mL. For this suspension, a solution prepared by diluting Tween 20 4000 times with deionized water was used. This rice blast conidia suspension was sprayed onto rice plants, and the plants were infected for 24 hours in a dark, moist room. The rice plants were then cultivated in a greenhouse at 25°C / 18°C day and night, and the control titer was calculated using the following formula based on the number of blast lesions that appeared on the rice leaves 7 to 9 days after inoculation. The presence or absence of a synergistic effect was then tested using the Colby's formula below.

[0070] Control titer = ((number of lesions in untreated area - number of lesions in treated area) / number of lesions in untreated area) x 100

[0071] (Colby's formula) Theoretical value = (control value A + control value B) - (control value A x control value B) / 100

[0072] The results in the tables below confirm that the actual control values ​​exceeded Colby's theoretical values, demonstrating a synergistic effect.

[0073]

[0074]

[0075]

[0076]

[0077]

[0078]

[0079]

[0080]

[0081]

[0082]

[0083]

[0084]

[0085]

[0086]

[0087]

[0088]

[0089]

[0090]

[0091] (Test Example 2) Long-term control effect against rice blast Aqueous acetone solutions (plant disease control compositions) prepared as follows were used as test solutions, and control values ​​and theoretical values ​​were calculated. The results are shown in Tables 19 and 20. Tebufloquine and each of the fungicides listed in Tables 19 and 20 were dissolved in acetone. This acetone solution was diluted with water to the concentrations listed in Tables 19 and 20, and a 1 / 1,000 volume of a wetting agent (Neoestellin, manufactured by Kumiai Chemical Industry Co., Ltd.) was added to prepare a spray solution. 15 g of rice (variety: Jikkoku) seeds were sown in a small 30 cm x 20 cm tray and grown in a greenhouse at 25°C / 18°C day and night.

[0092] On the other hand, 1 × 10 conidia of rice blast fungus (Pyricularia oryzae) cultured on an agar medium were added. ４ ~5 x 10 ４ The blast conidia were suspended at a concentration of 1000 conidia / mL. This suspension was prepared by diluting Tween 20 4000 times with deionized water. This blast conidia suspension was sprayed onto rice seedlings at the two-leaf stage, and the seedlings were infected for 24 hours in a dark, moist room. The rice seedlings were then cultivated in a greenhouse, and blast lesions were observed on the rice leaves 7 to 9 days after inoculation.

[0093] After confirming the presence of lesions on two leaves, 12 mL of the spray solution was sprayed on the plants, which were then allowed to dry naturally in a room, and then left to stand in a moist room (temperature 25°C, humidity 100%) for 24 hours to allow natural infection with the rice blast fungus in the tray.

[0094] After another week, the rice seedlings were similarly allowed to infect naturally for 24 hours. The rice seedlings were then cultivated for 7-9 days in a greenhouse set at 25°C / 18°C day and night, and the number of rice blast lesions formed on the expanded uppermost leaves of 50 randomly selected seedlings was counted. The control value was calculated using the following formula based on the lesion counts obtained. The presence or absence of a synergistic effect was then tested using Colby's formula.

[0095] Control titer = ((number of lesions in untreated area - number of lesions in treated area) / number of lesions in untreated area) x 100

[0096] (Colby's theoretical formula) Theoretical value = (control value A + control value B) - (control value A x control value B) / 100

[0097] The results in Tables 19 and 20 shown below confirmed that the actual control values ​​far exceeded the theoretical values ​​of Colby, demonstrating a synergistic effect.

[0098]

[0099]

[0100] The plant disease control composition of the present disclosure has excellent control effect against rice blast and is useful for agricultural purposes.

[0101] The disclosure of Japanese Patent Application No. 2022-052592, filed on March 28, 2022, is incorporated herein by reference in its entirety. In addition, all documents, patent applications, and technical standards described herein are incorporated herein by reference to the same extent as if each individual document, patent application, and technical standard was specifically and individually indicated to be incorporated by reference.

Claims

1. Contains tebufloquine and fungicides other than tebufloquine as active ingredients, The fungicide may be pyraclostrobin, picoxystrobin, fluoxastrobin, mandestrobin, trifloxystrobin, azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, A plant disease control composition comprising at least one selected from the group consisting of fluconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simeconazole, mefentrifluconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, penflufen, impilfluxam, fluindapyr, pyraziflumid, penthiopyrad, fluopyram, pyridaclomethyl, pyroquilon, and ipflufenoquin.

2. The plant disease control composition according to claim 1, wherein the fungicide comprises at least one selected from the group consisting of pyraclostrobin, picoxystrobin, fluoxastrobin, mandestrobin, trifloxystrobin, prothioconazole, mefentrifluconazole, cyproconazole, difenoconazole, hexaconazole, propiconazole, tebuconazole, penflufen, impirfluxam, pyraziflumid, pyroquilon, and ipflufenoquin.

3. The plant disease control composition according to claim 1, wherein the plant disease is rice blast disease.

4. A formulation comprising the plant disease control composition according to any one of claims 1 to 3.

5. The formulation according to claim 4, which is selected from wettable powders, emulsifiable concentrates, flowable concentrates, water dispersible granules, dry flowable concentrates, dusts, DL dusts, FD dusts, microcapsules, granules, dust granules, jumbo granules, packs and aerosols.

6. A method for controlling plant diseases, comprising applying the plant disease control composition according to any one of claims 1 to 3 to a plant disease.

7. The method for controlling a plant disease according to claim 6, wherein the plant disease is rice blast disease.

8. 7. The method for controlling plant diseases according to claim 6, wherein the application comprises at least one of foliage application and nursery box treatment.

9. The method for controlling plant diseases as described in claim 7, wherein the application includes at least one of foliage spraying and seedling tray treatment.