Composition of complete dietary food for cats with exocrine pancreatic insufficiency

Abstract

FIELD: veterinary medicine and dietetics.SUBSTANCE: development of complete feed compositions that can provide a therapeutic effect in cases of exocrine pancreatic insufficiency. The composition of a complete dietary feed for cats with exocrine pancreatic insufficiency has been developed in the following ratio, wt.%: grain part: mixture of rice, wheat, hulled barley and corn – 37.0; protein part of plant origin: isolated soy protein, beet pulp, wheat bran, flax seeds – 22.0; protein part of animal origin: feather meal, chicken liver, egg powder – 25.0; mineral supplement: feed chalk, monocalcium phosphate, table salt, plantain seeds Plantago psyllium, mannanoligasaccharides with beta-glucans and lutein – 2.0; vitamin premix: A, D3, E, K, B1, B2, B3, B5, B6, B12, Bc, H, taurine, inulin, beech lignocellulose, complex of natural fulvic and humic acids – 2.5; flavor enhancer in the form of enzymatic hydrolysate of pork and chicken by-products – 3–3.5; brewer's yeast – 2.5–3.0; a mixture of fish and chicken fat – 5.0–6.0.EFFECT: obtaining food for cats with exocrine pancreatic insufficiency, which is easily reproducible, clinically effective, and convenient in dosing and use.1 cl, 3 tbl, 1 ex

Description

[0001] The invention relates to veterinary medicine and dietetics, namely to the development of complete feed compositions that can provide a therapeutic effect in exocrine pancreatic insufficiency.

[0002] Currently, digestive system diseases account for 35% of all non-communicable diseases. Gastrointestinal diseases are among the most common in dogs and cats worldwide, accounting for approximately 25% of all visits to veterinary clinics. One of the most effective methods of preventing and treating these pathologies is dietary therapy.

[0003] The composition of sheep feed (SU 670293) is known to prevent obesity in these animals. A drawback of this composition is the lack of a pronounced positive effect on the gastrointestinal tract in general and the pancreas in particular.

[0004] A dry kibble food for dogs (BY 12952 C1) is also well-known, allowing them to fully meet their physiological needs. A drawback of this formula is the lack of a pronounced positive effect on the gastrointestinal tract in general, and the pancreas in particular.

[0005] The technical result is a solution to the problem of creating a complete dietary food composition for cats with exocrine pancreatic insufficiency. The advantages of this composition include its ease of reproducibility, clinical effectiveness, and ease of dosing and use.

[0006] To achieve the technical result, the compositions of a complete dietary food for cats with exocrine pancreatic insufficiency are proposed in the following ratio, mass %:

[0007] 1) For dry complete feed:

[0008] - grain part (mixture of rice, wheat, hulled barley and corn) - 37.0

[0009] - protein part of plant origin (isolated soy protein, beet pulp, wheat bran, flax seeds) - 22.0

[0010] - protein part of animal origin (feather meal, chicken liver, egg powder) - 25.0

[0011] - mineral supplement (feed chalk, monocalcium phosphate, table salt, plantain seeds Plantago psyllium, mannanoligasaccharides with beta-glucans and lutein) - 2.0

[0012] - vitamin premix (A, D3, E, K, B1, B2, B3, B5, B6, B12, Bc, H, taurine, inulin, beech lignocellulose, complex of natural fulvic and humic acids) - 2.5

[0013] - flavor enhancer in the form of enzymatic hydrolysate of pork and chicken by-products -3-3.5

[0014] - brewer's yeast - 2.5-3.0

[0015] - a mixture of fish and chicken oil - 5.0-6.0

[0016] 2) For canned complete feed:

[0017] - meat and animal products (chicken, egg mixture) - 39.0

[0018] - plant components and their processed products (carrots, wheat flour, corn starch, beet fiber, wheat fiber, flaxseed flour) - 5.0

[0019] - vitamins and minerals (vitamin-mineral premix, table salt, dextrose, vitamin C, tripolyphosphate) - 1.0

[0020] - fats and oils (fish oil, sunflower oil) - 0.6

[0021] - amino acids (taurine) - 0.35

[0022] - thickeners - 0.2

[0023] - water - 53.85

[0024] Thus, the food consists of easily digestible ingredients, is low in fat, and contains the necessary levels of sodium and potassium. It uses specialized protein and carbohydrate sources, which reduce the risk of adverse reactions to the product. The food contains a complex of fermentable (prebiotic) and non-fermentable dietary fiber, as well as a postbiotic, which helps normalize the gastrointestinal microflora and improve the animal's health.

[0025] The use of specialized dietary food for gastrointestinal diseases is an important adjunct to treatment. These food formulations provide the following benefits:

[0026] - Easily digestible feed (protein digestibility 92.0%).

[0027] - Moderate energy content and low fat content to help control weight and reduce the strain on the digestive system.

[0028] - Contains a complex of fermentable dietary fiber (prebiotics) and non-fermentable dietary fiber to normalize the microflora of the gastrointestinal tract and improve its health.

[0029] Humic and fulvic acids (postbiotic) increase the body's natural resistance, exhibit a positive therapeutic effect, activate digestion, improve the absorption of nutrients and minerals in feed, have strong antioxidant activity, protect the liver from damage, are a powerful natural electrolyte, and are characterized by antitoxic properties.

[0030] - Acceptable electrolyte levels.

[0031] - High palatability of the feed.

[0032] - Optimal level of Omega-3 / Omega-6 unsaturated fatty acids.

[0033] - High level of B vitamins.

[0034] - Organic form of microelements.

[0035] To obtain dry food, the following steps are implemented:

[0036] 1. The barley is peeling.

[0037] 2. The grain mixture is weighed and ground: rice, wheat, barley without films, corn.

[0038] 3. Weigh and mix the following ingredients: ground grain mixture, isolated soy protein, wheat gluten (for cats), wheat bran, sugar beet pulp, flaxseed, egg powder, brewer's yeast, mineral sources of calcium and phosphorus, table salt, animal / poultry meal.

[0039] 4. The above mixture is crushed.

[0040] 5. After grinding, a vitamin and mineral premix is ​​added to the mixture, after which everything is thoroughly mixed. The premix is ​​ready for the next technological process.

[0041] 6. Chicken liver is weighed, ground into minced meat and prepared into an emulsion by adding water.

[0042] 7. Liquid chicken fat is weighed and a natural antioxidant based on rosemary is added to it.

[0043] 8. Premix, liver emulsion and fish oil are introduced into the extruder.

[0044] 9. After extrusion, thanks to the properties of the premix, the technical characteristics of the extruder, and the help of the die and knife, the feed acquires a specific texture, shape, and size of granules.

[0045] 10. The feed granules are dried.

[0046] 11. Dry granules are placed in a vacuum sprayer, where they are sprayed with liquid chicken fat and enzymatic hydrolysate of pork and chicken by-products.

[0047] 12. The granules are cooling.

[0048] 13. Food packaging.

[0049] To obtain canned food, the following steps are implemented:

[0050] 1. Raw material preparation:

[0051] - Weighing of meat raw materials.

[0052] - Grinding of meat raw materials.

[0053] - Dosing dry ingredients.

[0054] 2. Preparing the minced meat mixture using a mixer:

[0055] - Mixing minced meat with dry ingredients.

[0056] - Second fine grinding on an emulsifier after mixing with dry ingredients.

[0057] - Pumping minced meat / emulsion into a storage tank for feeding to the steam tunnel.

[0058] 3. Forming pieces:

[0059] - Feeding minced meat / emulsion through the extruder heads onto the belt (conveyor) of the steam tunnel.

[0060] - Cutting steamed strips of minced meat / emulsion into pieces.

[0061] - The pieces enter the buffer tank for mixing with the sauce before feeding to the packaging machine.

[0062] 4. Making sauce / jelly:

[0063] - Mixing cold water and dry ingredients in a saucepan.

[0064] - Pumping sauce into a buffer tank to mix with the pieces before feeding to the packaging machine.

[0065] 5. Packing pieces and sauce into individual (primary) packaging.

[0066] 6. Sealing of products (sealing).

[0067] 7. Autoclaving of products (sterilization).

[0068] 8. Packing products into group packaging.

[0069] The daily feeding rate may vary depending on the age, activity, condition and living conditions of the animal.

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[0073] The essence of the invention is illustrated by the following example. Animals for the study were selected using the pair-analog method. All animals were sterilized, vaccinated according to the vaccination schedule, and previously underwent helminthological testing.

[0074] Group formation: 3 experimental groups of 10 animals each:

[0075] - experimental group 1 - non-pedigree cats with gastrointestinal diseases of various etiologies (with damage to the pancreas), which are given a dry and canned form of a veterinary diet based on the above-described food.

[0076] - experimental group 2 - non-pedigree cats with gastrointestinal diseases of various etiologies (with damage to the pancreas), which are given a dry form of a veterinary diet based on the above-described food.

[0077] - experimental group 3 - non-pedigree cats with gastrointestinal diseases of various etiologies (with damage to the pancreas), which were given a diet.

[0078] Feeding animals for 6 months according to the characteristics of the experimental groups.

[0079] No additional drug treatment was carried out on the animals.

[0080] Sampling: Bio-samples from cats were collected three times during the study (before the start of feeding; 3 months after the start of feeding, 6 months after the start of feeding).

[0081] In order to quantitatively determine normal, opportunistic and pathogenic microorganisms, their growth and development in the control group, the experimental group of cats consuming dry food and the experimental group of cats consuming dry and wet food in the diet, the following were identified:

[0082] 1. Bifidobacterium spp. (Bifidobacteria)

[0083] 2. Lactobacillus spp. (Lactobacilli)

[0084] 3. Escherichia coli with normal enzymatic activity

[0085] 4. Escherichia coli with weak enzymatic properties

[0086] 5. Escherichia coli lactose-negative

[0087] 6. Escherichia coli hemolytic

[0088] 7. Enterococcus spp. (Enterococci)

[0089] 8. Proteus spp. (Microbes of the genus Proteus)

[0090] 9. Klebsiella spp. (Klebsiella)

[0091] 10. Other opportunistic enterobacteria

[0092] 11. Enterobacter spp. (Enterobacter)

[0093] 12. Staphylococcus aureus (Golden Staphylococcus)

[0094] 13. Staphylococcus epidermidis (Epidermal staphylococcus)

[0095] 14. Staphylococcus saprophyticus (Staphylococcus aureus)

[0096] 15. Candida fungi

[0097] 16. Non-fermenting gram-negative bacteria

[0098] 17. Pseudomonas spp. (Pseudomonas aeruginosa)

[0099] 18. Clostridium spp. (Clostridium)

[0100] 19. Clostridium difficile.

[0101] The research results are presented in Tables 1-3.

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[0109] The research revealed that in the intestinal microbiome of cats, into whose diet dry and wet food was introduced, the level of beneficial microflora, namely representatives of bifidobacteria and lactobacilli, quickly reached the optimal content (10 9 -10 10 CFU / g and 10 7 -10 8 CFU / g, respectively). When introducing dietary food into the diet of cats (the dry food group and the dry + wet food group), a decrease in the level of opportunistic and pathogenic microflora was recorded relative to the control group, namely, representatives of Escherichia coli with hemolytic activity, Staphylococcus aureus, Enterococcus spp.

[0110] During the study, a decrease in the number of Escherichia coli with normal enzymatic activity was recorded in all study groups.

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