Systems and methods for imaging and modulating the nervous system using an ultrasound-based brain-computer interface

Ultrasound-based systems for neural imaging and modulation address the limitations of current neurotechnologies by enabling high-resolution, minimally invasive monitoring and treatment of neural activity at broad scales, facilitating effective management of brain disorders through iterative closed-loop neuromodulation.

WO2025007077A2PCT designated stage expired Publication Date: 2025-01-02FOREST NEUROTECH LLC
View PDF 0 Cites 1 Cited by

Patent Information

Application Number
PCT/US2024/036281
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-11-14
Filing Date
2024-06-29
Publication Date
2025-01-02

AI Technical Summary

Technical Problem

Current neurotechnologies face limitations in monitoring and manipulating neural activity at sufficient temporal and spatial scales, being either invasive, lacking spatial resolution, or unsuitable for real-time interactions with neuronal circuits, which hinders effective treatment of brain disorders.

Method used

The development of ultrasound-based systems and methods for imaging and modulating the nervous system using implantable ultrasound transducers, enabling macroscale interfacing with the brain for high-resolution neuroimaging and neuromodulation, even during clinically relevant behaviors, through a closed-loop system that iteratively adjusts neuromodulation based on imaging data.

Benefits of technology

This approach allows for minimally invasive, high-resolution monitoring and modulation of neural activity at broad scales, improving treatment efficacy for brain dysfunctions by providing precise and individualized therapeutic interventions.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure US2024036281_02012025_PF_FP_ABST
    Figure US2024036281_02012025_PF_FP_ABST
Patent Text Reader

Abstract

Devices, methods, and systems related to ultrasound imaging or modulating of the nervous system are described. The devices may comprise, for example, one or more ultrasound transducers, wherein an ultrasound transducer from the one or more ultrasound transducers can comprise an implantable ultrasound transducer, wherein the implantable ultrasound transducer can comprise a sonolucent window. The methods and systems may also comprise, for example, a method of imaging and / or modulating the nervous system of a subject using the one or more ultrasound transducers. The method of imaging and / or modulating the nervous system of the subject can be based on a closed-loop operation, wherein an iteration of the imaging and / or the modulating of the nervous system is based on a prior iteration. The closed-loop operation can comprise ultrasound imaging and ultrasound-based modulating or electrophysiological modulating. The methods can further comprise methods of analyzing ultrasound data, such as via an artificial neural network.
Need to check novelty before this filing date? Find Prior Art

Citation Information

Cited By

  • Electric ultrasonic parameter control method and device

    CN119896812A