Pharmaceutical composition, formulation containing pharmaceutical composition, kit containing pharmaceutical composition, preparation method for pharmaceutical composition, and use of pharmaceutical composition

Abstract

A pharmaceutical composition, a formulation containing the pharmaceutical composition, a kit containing the pharmaceutical composition, a preparation method for the pharmaceutical composition, and a use of the pharmaceutical composition. The pharmaceutical composition comprises the following components: an active pharmaceutical ingredient and a hot-melt adhesive, wherein the mass percentage of the active pharmaceutical ingredient is 0.3%-50%; the hot-melt adhesive is Poloxamer P188 and / or Poloxamer P407; and the mass percentage of the hot-melt adhesive in the pharmaceutical composition is 5%-30%. According to the pharmaceutical composition, the formulation containing the pharmaceutical composition, and the kit containing the pharmaceutical composition, the active pharmaceutical ingredient can be rapidly released to achieve a fast onset of action, the stability of the active pharmaceutical ingredient is improved, the swallowing of patients can be further improved, and the patient compliance during actual medicine-taking can be further improved.

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