Cosmetic compositions and uses thereof

Abstract

The invention relates generally to cosmetic compositions and specifically topically applied cosmetic formulations comprising natural active ingredients. In particular, the invention relates to topical cosmetic compositions comprising verbascoside and / or echinacoside, used to address cosmetic skin concerns such as dry skin, inflammation, hyperpigmentation, acne, photo-ageing and other aesthetic features such as radiance.

Description

[0001]COSMETIC COMPOSITIONS AND USES THEREOF FIELD The invention relates generally to cosmetic compositions and specifically topically applied cosmetic formulations comprising natural active ingredients. In particular, the invention relates to cosmetic compositions, and more particularly, “dermocosmetics”, for example, in highly functioning or science-based topical applications to address cosmetic skin concerns such as dry skin, inflammation, hyperpigmentation, acneic production, prevent and reverse photo-ageing and other aesthetic features such as radiance. BACKGROUND The skin is the largest organ of our body and acts as our physical shield against the external environment, retaining complex structure, function, metabolic action and regulatory processes. There are four predominant layers of dermal tissue including the stratum corneum, epidermis, dermis and adipose tissue. There is a basal layer between the epidermis and dermis which gives rise to cellular communication, signalling and maintains a repository of extracellular proteins. The pH of healthy skin ranges from 4.8-5.5, and this is maintained precisely. This is due to an acid mantle which is present over the skin’s barrier. Pollution, temperature, dermal pathogens and UV exposure disrupts skin function, barrier function, pH value and a subsequent cascade of events may ensue. Dermal protein signalling and the production of growth factors cannot occur optimally in alkaline skin states. Patients with dermatological skin disorders such as eczema or dermatitis have higher pH values which are closer to neutral or slightly alkaline. As a consequence, these subjects and their skin are unable to form lipids, ceramides or other integral structural features of the dermal tissue. Moreover, acidity is required for appropriate function and regulation of the skin’s microbiome. The stratum corneum is the uppermost layer, commonly referred to as the barrier, where the skin’s microbiomic community reside in unison with corneocytes. Generally, keratinocytes are structured in a manner which prevents external aggressors from entering the skin and again, which is why the term ‘barrier’ is often used. This is a matrix of intercrossed involucrin and keratohyalin which form the basis of a cornified involucre. Intercellular spaces exist within these matrices or crossed structure where lipids accumulate; simply put, these lamellar lipids ‘fill in the gaps’. However, this lipid bi- layer contains polar heads and intracellular channels which allow the passing and binding of hydrophilic substances. However, this layer usually presents problems for modern skincare formulations due to this structure and tortuous pathway as described by dermatologists for substances to pass through. The epidermis is responsible for pigment creation, holding melanocytes, as well as generalised presence of keratinocytes and other antigen-presenting cells. The dermis is a reservoir of vasculature which innervates the epidermis and is responsible for the production of growth factors and other messenger proteins or enzymes as fibroblasts are abundant within this layer. The adipose tissue resides in the ‘bottom’ layer which lines the connective tissue network between the dermis and the subcutaneous layer beneath the skin. The skin is a complex organ and is affected materially by extrinsic and intrinsic factors which lead to depletion, inflammation, irradiation, degradation or reconstruction, regeneration, rejuvenation and endogenous healing processes. Extrinsic factors are the major cause of ageing within skin, most notably from UV-A induced irradiation and further lipid peroxidation. The generation of reactive oxygen species and free radicals pose various issues including induction of matrix metalloproteinase activity, activation of inflammatory pathways such as the NF-kB or TNF-alpha sequences, tyrosinase based action or induction of disordered melanosome function. Another more insidious culprit which leads to skin damage and photo-aging is blue light. Blue light is emitted visible light between the wavelengths of 380 to 500 nm, also referred to as high-energy visible (HEV) light. The main source of blue light is sunlight, but digital computer screens, light- emitting diodes (LEDs), and fluorescent lighting serve as additional sources. Concerns about the negative effects of blue light on the skin have rapidly increased over the past 15 years, and consequently, the urge to learn more about this topic is increasing as well together with cosmetic remedies to minimise or reduce the damaged caused by blue light exposure. The aforementioned effects gives rise to issues including barrier dysfunction, pathogenic material generation via a disordered microbiome which may cause acne, alongside inflammatory pathways which cause acneic production, disordered sebum regulation, degradation of proteins such as collagen and elastin and suppress fibroblast proliferation. Moreover, intrinsic factors such as DNA and telomerase dysfunction shorten these caps or telomeres and remains the biological nature of ageing with loosened DNA coiling and structure. However, most of these features are gradual, despite their nefarious nature. Dysregulated pH of the skin will result in disorders and dermal complications from very early ages. Modern skincare and evolving advancements have revealed high functioning, scientific and dermatologically based dermocosmetics to address these factors. Genetics play a part in how skin is expressed within an individual, however at least 80% of all skin damage and deterioration is a result of UV-A exposure, however as we spend more time in from of computer screens the additional aging effects of blue light become an increasing concern. The present invention seeks to address one or more of the above current problems in the art. SUMMARY The present inventors have identified a need to develop an improved cosmetic composition with blue light reflective, absorption, or filtering capabilities. The chemical compositions of the present invention, which are presented as water based liquid compositions act as improved topically applied compositions with natural reflective, absorption, and filtering agents to treat various cosmetic skin conditions (referred herein as “dermal conditioning”), or mixed with additional ingredients, for instance, via emulsion and other techniques (such as sonication) to produce other dermatologically beneficial formulations. Without wanting to be bound by any particular theory, the present inventors have identified and developed naturally sourced actives to provide novel cosmetics, which are beneficial to the dermal layers. The compositions may be complemented by additional components / ingredients may encourage endogeny, inhibit inflammation and enzyme processes which cause ageing, acneic production, hyperpigmentation and dermal dehydration. The effects of UV and HEV light on skin over time can be profound. Exposure to sunlight and tanning machines is the main source of UV light (both UV-A and UV-B). Over exposure to UV-B is the main cause of skin burn with UV-B only managing to penetrate the epidermis layer. This can lead to increased melanin and result in photo-aging, hyperpigmentation, sun allergies, freckles and melisma. UV-A light can penetrate pass the epidermis and into the dermis layer. This can lead to hyaluronic acid decrease (which causes dryness, inflammation, and skin texture changes), collagen fibre damage (causing fine lines and wrinkles and loss of skin tone), DNA Damage (ROS and oxidative stress to skin lipids, proteins and cell regeneration slowed), and degradation of elastin production (ie, loss of elasticity and skin resilience). High-energy visible (HEV) light (blue light) is also a production of sunlight, but digital computer screens, light-emitting diodes (LEDs), and fluorescent lighting serve as additional sources. In a modern world people are nowadays all the more exposed to blue light by spending large amounts of time in front of computers (and the like). Blue light can penetrate even deeper than UV-A and UV-B and damage the hypodermis layer. This leads to subcutaneous fat changes and ultimaelty impairs the support base of skin. In certain embodiments the compositions disclosed herein are able to, in part, penetrate and reside in the epidermis and / or dermis layer protecting the hypodermis layer from the damaging effects of blue light. In certain embodiments the compositions disclosed herein are able to, in part, penetrate and reside in the epidermis layer protecting the dermis and hypodermis layer from the damaging effects of blue light and UV light. The compositions disclosed herein may be developed further to offer clinical grade formulations within Dermatology or Cosmetic Procedure Practices. Such expansions may include cosmetic procedural formulations such as a novel ‘filler’ preparation. The present invention also contemplates the development of novel cosmetic and dermocosmetics compositions with an acidic buffer capacity to ensure optimal dermal outcomes. Thus, the present invention is predicted, in part, on the understanding that pH control plays a crucial role in healthy skin function conducive towards dermal conditioning and the inventors have developed a series of cosmetic aqueous based solutions which provide effective dermal conditioning properties at a pH of from 3 to about 6 which are capable of minimising / reducing or preventing photo-aging. In certain embodiments the present cosmetic compositions of the present invention are specially designed to reduce or prevent photo-ageing in a subject and contain as active ingredients plant extracts that comprise mixtures of verbascoside and echinacoside. Verbascoside (structure below) is a caffeoyl phenylethanoid glycoside in which the phenylpropanoid caffeic acid and the phenylethanoid hydroxytyrosol form an ester and an ether bond respectively, to the rhamnose part of a disaccharide, namely β- (3′,4′-dihydroxyphenyl)ethyl-O-α-L-rhamnopyranosyl(1→3)-β-D-(4-O-caffeoyl)- glucopyranoside. Verbascoside can be found in species in all the plant families of the order Lamiales (syn. Scrophulariales). Only two examples are known from outside the order, in the class Asterids. In the family Lamiaceae, it can be found in the medicinal plants in the genus Phlomis, in the Scrophulariaceae, in Verbascum phlomoides, Verbascum mallophorum, or, in the family Buddlejaceae, in Buddleja globosa or Buddleja cordata, in the family Bignoniaceae, in Pithecoctenium sp and Tynanthus panurensis, in the family Orobanchaceae, in Cistanche sp and Orobanche rapum-genistae, in the Plantaginaceae, in Plantago lanceolata, in Verbenaceae, in Verbena officinalis (common vervain), Aloysia citrodora (lemon verbena) and Lantana camara, in the Oleaceae, in Olea europaea (olive), in the Lentibulariaceae, in the carnivorous plant Pinguicula lusitanica, and, in the Byblidaceae, in Byblis liniflora. Echinacoside which is a natural plant derived phenol, is a caffeic acid glycoside from the phenylpropanoid class. It is constituted from a trisaccharide consisting of two glucose and one rhamnose moieties glycosidically linked to one caffeic acid and one dihydroxyphenylethanol (hydroxytyrosol) residue at the centrally situated rhamnose. This water-soluble glycoside is a distinctive secondary metabolite of Echinacea angustifolia and Echinacea pallida (to about 1%) but only occurs in trace amounts in Echinacea purpurea. It is also isolated from Cistanche spp. Echinacoside was first isolated Echinacea angustifolia and has been shown to have weak antibiotic activity in vitro. As such the present compositions are thought to also provide support to acneic skin. Accordingly, in one aspect the invention provides a water based cosmetic composition comprising: (i) about 0.03-6% wt / wt of a plant extract which comprises both verbascoside and echinacoside; and (ii) about 1-4% wt / wt of 1,3-propandiol. In certain embodiments the present cosmetic compositions of the present invention are specially designed to reduce or prevent photo-ageing in a subject and contain as active ingredients plant extracts that comprise mixtures of verbascoside and echinacoside. In certain embodiments the present cosmetic compositions of the present invention are specially designed to reduce or prevent photo-ageing in a subject and contain as active ingredients plant extracts that comprise bisabolol or synthetic bisabolol (structure shown below): Bisabolol, or more formally α-(−)-bisabolol or also known as levomenol, is a natural monocyclic sesquiterpene alcohol (a terpenoid). It is a colourless viscous oil that is the primary constituent of the essential oil from German chamomile (Matricaria recutita) and Myoporum crassifolium. High concentrations of bisabolol can also be found in certain medicinal cannabis cultivars. It is poorly soluble in water and glycerine, but soluble in ethanol (alcohol) which is also used in the formulations herein. The enantiomer, α-(+)-bisabolol, is also found naturally but is rare. Synthetic bisabolol is usually a racemic mixture of the two, α-(±)-bisabolol. In respect to the present invention it is considered that in embodiments which contain this ingredient there is a triple light action effect which protects against UVA and UVB and HEV. In certain embodiments the present cosmetic compositions of the present invention are specially designed to reduce or prevent photo-ageing in a subject and contain as active ingredients plant extracts that comprise bisabolol (or synthetic bisabolo) and a Polygonum aviculare extract. This Polygonum aviculare extract is a member of the Polygonaceae family of plants for instance in the knotweed family or smartweed or buckwheat family, which has been known for its antioxidant and anti-obesity effects. Polygonum aviculare L. and its active compounds, quercitrin hydrate, caffeic acid, and rutin, activate the Wnt / β-catenin pathway are also known to and induce cutaneous wound healing. The present inventors use the extract to aid the reduction or prevention of photo-ageing an in particular photo- ageing caused by exposure to blue light. DETAILED DESCRIPTION All wt / wt% values mentioned herein refer to wt / wt% amounts relative to the total weight of all ingredients in aqueous compositions of the present invention (including the water content). In certain embodiments the water based (or aqueous based) compositions of the present invention comprise from 85-96% wt / wt water content, such as about 86, 87, 88, 89, 90, 91, 92, 93, 94, 95 or about 96% wt / wt water. In certain other embodiments where the compositions are in the form of a balm the water content may be as low as 0.2-5% wt / wt such as about 0.3-1% wt / wt of the total composition. Accordingly, the skilled person will understand The skilled person will understand that based on a high water content the compositions of the present invention will normally be presented in the form of lightweight non-viscous serums or mists. The term "subject" or "subjects" encompasses as used herein refers to human subjects. As used herein the terms "compositions" and "formulations" are used interchangeably. The term “dermal conditioning” refers to the normalisation of the skin tissue after having a cosmetic condition requiring treatment or for cosmetic purposes. Such conditions includes birthmarks, botox injections or filler preparation due to extrinsic ageing concerns, acne scarring, stretch marks, dry skin, inflammation, hyperpigmentation, acneic production, ageing and other aesthetic features such as radiance. The present invention is particularly concerned with dermal conditioning associated with photo-aging. Dermal conditioning is a complex process which is characterised by intercalating degradation and re-assembly of connective tissue and epidermal layer and will largely depend on the condition which has caused the skin to be preforming non-optimally. The pH value influences indirectly and directly all biochemical reactions taking place within and on the skin. In the modern world and with hour upon hour of exposure to blue light through computer use, collagen is broken down through oxidative stress by ROS (reactive oxidative species). Primarily this is caused by the compound Flavin, naturally in the skin, absorbing blue light (380 to 500 nm- also known as high-energy visible (HEV)). Studies have shown that exposure (even for as little as 60 minutes) from blue light emitting electronic devices (e.g., computer screens) triggers changes in skin cells such as cell shrinkage and death. In certain embodiments the plant extract which comprises both verbascoside and echinacoside is selected from one or more of the following: Buddleja Officinalis Flower Extract, Buddleija davidii, Australian Red Centre Lime, Banksia, Blue Cypress, Davidon Plum, Desert Lime, Emu Apple / Muntries, Finger Lime Caviar, Flame Tree, Flannel Flower, Kakadu Plum, Kangaroo Paw, Karkalla, Lemon Aspen, Lemon Myrtle, Lilli- Pilli-Riberry, Mountain Pepper Berry / Leaf, Native River Mint, Native Seaweed- Tasmania Kelp, Native Snowflower / Tea Tree, Pink Ice Finger Lime, Quandong, Queen Garnet, Red Champagne Finger Limes, Rosella, Silky Oil Grass, Snake Vine, Strawberry Gum, Sunrise Lime, Tasmania Blue Gum, Tasmania Lavender, Waratah and Waxflower. In certain embodiments the plant extract is characterised with from about 5-25% wt / wt of verbascoside, based on the dry weight of the plant extract. In another embodiment the plant extract is an extract from rhizomes of Hedychium Coronarium, the butterfly ginger plant from Madagascar. In certain embodiments the plant extract extract comprises bisabolol (or synthetic bisabolo). In certain embodiments the plant extract extract comprises bisabolol (or synthetic bisabolo) and a Polygonum aviculare extract. In certain embodiments the plant extract is characterised with from about 1-10% wt / wt of echinacoside, based on the dry weight of the plant extract. In certain embodiments the plant extract is characterised with from about 5-25% wt / wt of verbascoside, and about 1-10% wt / wt of echinacoside, based on the dry weight of the plant extract. In certain embodiments, the composition is characterised as having a pH of from about 3 to about 6. Accordingly, in a further aspect the invention provides a water-based cosmetic composition comprising: (i) about 0.03-6% wt / wt of a plant extract which comprises both verbascoside and echinacoside; and (ii) about 1-4% wt / wt of 1,3-propandiol, wherein the plant extract which comprises both verbascoside and echinacoside is selected from one or more of the following: Buddleja Officinalis Flower Extract, Buddleija davidii, Australian Red Centre Lime, Banksia, Blue Cypress, Davidon Plum, Desert Lime, Emu Apple / Muntries, Finger Lime Caviar, Flame Tree, Flannel Flower, Kakadu Plum, Kangaroo Paw, Karkalla, Lemon Aspen, Lemon Myrtle, Lilli-Pilli-Riberry, Mountain Pepper Berry / Leaf, Native River Mint, Native Seaweed-Tasmania Kelp, Native Snowflower / Tea Tree, Pink Ice Finger Lime, Quandong, Queen Garnet, Red Champagne Finger Limes, Rosella, Silky Oil Grass, Snake Vine, Strawberry Gum, Sunrise Lime, Tasmania Blue Gum, Tasmania Lavender, Waratah and Waxflower, and wherein the composition is characterised as having a pH of from about 3 to about 6. In a further aspect the invention provides a water-based cosmetic composition comprising: (i) about 0.03-6% wt / wt of a plant extract which comprises both verbascoside and echinacoside; and (ii) about 1-4% wt / wt of 1,3-propandiol, wherein the plant extract which comprises both verbascoside and echinacoside is selected from one or more of the following: Buddleja Officinalis Flower Extract, Buddleija davidii, Australian Red Centre Lime, Banksia, Blue Cypress, Davidon Plum, Desert Lime, Emu Apple / Muntries, Finger Lime Caviar, Flame Tree, Flannel Flower, Kakadu Plum, Kangaroo Paw, Karkalla, Lemon Aspen, Lemon Myrtle, Lilli-Pilli-Riberry, Mountain Pepper Berry / Leaf, Native River Mint, Native Seaweed-Tasmania Kelp, Native Snowflower / Tea Tree, Pink Ice Finger Lime, Quandong, Queen Garnet, Red Champagne Finger Limes, Rosella, Silky Oil Grass, Snake Vine, Strawberry Gum, Sunrise Lime, Tasmania Blue Gum, Tasmania Lavender, Waratah and Waxflower, and wherein the composition is characterised as having a pH of from about 3 to about 6, and further wherein the plant extract is characterised with from about 5-25% wt / wt of verbascoside, based on the dry weight of the plant extract, and / or the plant extract is characterised with from about 1-10% wt / wt of echinacoside, based on the dry weight of the plant extract. The present invention comprises about 0.03-6% wt / wt of a plant extract which comprises both verbascoside and echinacoside such about 0.03, 0.05, 0.1, 0.4, 0.8, 1.0, 1.2, 1.3, 1.5, 1.7, 1.9, 2.1, 2.2, 2.3, 2.5, 2.7, 2.9, 3.2, 3.4, 3.6, 3.8, 4.0, 4.2, 4.4, 4.6, 4.8, 5.0, 5.2, 5.4, 5.6, 5.8, or about 6.0% wt / wt or any range in between these two figures. The present invention comprises about 1-4% wt / wt of 1,3-propandiol such about 1.0, 1.2, 1.3, 1.5, 1.7, 1.9, 2.1, 2.2, 2.3, 2.5, 2.62.7, 2.82.9, 3.0, 3.2, 3.3, 3.5, 3.7, 3.9, or about 4.0 or any range in between these two figures. In certain embodiments, and in respect to anyone of the above aspects, the invention also comprises hyaluronic acid or a salt thereof, for instance, sodium hyaluronate. The hyaluronic acid or a salt thereof may be present in an amount of 0.05-0.5% wt / wt. Accordingly, in a further aspect the invention provides a water-based cosmetic composition comprising: (i) about 0.03-6% wt / wt of a plant extract which comprises both verbascoside and echinacoside; and (ii) about 1-4% wt / wt of 1,3-propandiol, wherein the plant extract which comprises both verbascoside and echinacoside is selected from one or more of the following: Buddleja Officinalis Flower Extract, Buddleija davidii, Australian Red Centre Lime, Banksia, Blue Cypress, Davidon Plum, Desert Lime, Emu Apple / Muntries, Finger Lime Caviar, Flame Tree, Flannel Flower, Kakadu Plum, Kangaroo Paw, Karkalla, Lemon Aspen, Lemon Myrtle, Lilli-Pilli-Riberry, Mountain Pepper Berry / Leaf, Native River Mint, Native Seaweed-Tasmania Kelp, Native Snowflower / Tea Tree, Pink Ice Finger Lime, Quandong, Queen Garnet, Red Champagne Finger Limes, Rosella, Silky Oil Grass, Snake Vine, Strawberry Gum, Sunrise Lime, Tasmania Blue Gum, Tasmania Lavender, Waratah and Waxflower, wherein the composition is characterised as having a pH of from about 3 to about 6, and the composition further comprises hyaluronic acid or a salt thereof in an amount of about 0.05-0.5% wt / wt. In further embodiments and with reference to the above aspects the compositions comprise one or more thickening or gelling agents. In certain embodiments, the thickening agents / gelling agents may be selected from agar, carrageenan, arrowroot, gum Arabic, gellan gum, guar gum, xanthan gum, alginic acid, sodium alginate, hypromellose, Tragacanth, Lecithin (also an emulsifier), Sclerotium Gum, and Pullulan (film forming compound, also functions in moisture-retention). For the purposes of reducing ROS on the skin and for compositional preservative reasons the compositions preferably also comprise one of more antioxidants. In certain embodiments, the antioxidants may be selected from Vitamins A, Vitamin E (and tocopheryl acetate – ATA), Vitamin C, carotenoids, polyphenols, Co-enzyme Q10, glutathione, and sodium benzoate. It will be appreciated by the skilled person that both verbascoside and echinacoside are also polyphenolic in nature and accordingly, and with respect to the present invention, not only serve are blue light filtering compounds but may also serve to reduce ROS as anti-oxidants. Certain compositions disclosed herein are presented as water-based compositions characterised as having a pH of from about 3 to about 6. As such, it may be necessary to add quantities of buffering agents such as lactic acid, citric acid, acetic acid, adipic acid, ascorbic acid, malic acid, fumaric acid and the like. In some embodiments the buffering agents are present in an amount of 0.1 to 2 %wt / wt of the total composition, such as about 0.10, 0.12, 0.15, 0.18, 0.20, 0.30, 0.50, 0.70, 0.90, 1.1, 1.2, 1.3, 1.5, 1.7, 1.9, or about 2.0% or any range in between these two figures. In other embodiments, the compositions of the present invention may be characterised as follows: 1 S S S Containing :Water Glycerin P S S 1 Accordingly, the compositions may also include: SiligelTM– which may be purchased by Lucas Meyer Cosmetics- which is a gelling agent, co-emulsifer, stabilizer and suspending agents comprising a mixture of Xantham Gum, Lecithin, Slerotium Gum, Pullulan and Silica. Geogard 221TM– is a commercially available preservative blend (organic acid based antimicrobial- dehydroacetic acid (DHA) and benzyl alcohol) designed to replace parabens and paraben bends. Accordingly, in certain embodiments the compositions of the present invention are paraben-free. ContacticalTM– is a commercially available water based mixture of hydrolyzed rhodophyceae extract with butylene glycol. This is a red algae extract which is added to the compositions to improve skin hydration as well as a good source of antioxidants In other embodiments, the compositions are in the form of liquids (e.g., serums) which may include solutions, suspensions, and emulsions. These compositions may contain, in addition to the active component, colorants, flavours, stabilisers / emulsifiers, buffers, artificial and natural sweeteners, dispersants, thickeners, solubilising agents, and the like. In other embodiments the compositions of the present invention include one or more of UV-A and / or UV-B cosmetically acceptable filters (sunscreen agents) such as octocrylene, ecamsule, dioxybenzone, bisoctrizole, ethylhexyl triazone, avobenzone, zinc oxide, iron oxide, titanium oxide, oxybenzone, and octyl methoxycinnamate. For topical administration to the epidermis the compounds according to the invention may also be further formulated as ointments, creams or lotions, or as a transdermal patch. Ointments and creams may, for example, be formulated with an aqueous or oily base with the addition of more quantities of suitable thickening and / or gelling agents. Lotions may be formulated with the aqueous base and will in general also contain one or more emulsifying agents, stabilising agents, dispersing agents, suspending agents, thickening agents, or colouring agents. In another aspect the invention also contemplates the use of pure verbascoside and / or pure echinacoside which has previously been purified from a plant extract (e.g., from column purification techniques, such as MPLC and HPLC), or has been synthetically produced. In this regard the amount of pure verbascoide in the compositions of the present invention may be in the range of about 0.03-4% wt / wt. In this regard the amount of pure echinacoside in the compositions of the present invention may be in the range of about 0.03-4% wt / wt. In this regard the amount of pure verbascoide and echinacoside in the compositions of the present invention may be in the range of about 0.03-4% wt / wt. Accordingly, in a further aspect the invention provides a cosmetic composition comprising: (i) about 0.03-4% wt / wt of pure verbascoside and / or echinacoside; and (ii) about 1-4% wt / wt of 1,3-propandiol, and wherein the composition is characterised as having a pH of from about 3 to about 6. In certain embodiments the cosmetic compositions of the present invention are in the form of a mist and is specially designed to reduce or prevent photo-ageing in a subject and contain as active ingredients plant extracts that comprise bisabolol (or synthetic bisabolo). In certain embodiments the cosmetic compositions of the present invention are in the form of a mist and is specially designed to reduce or prevent photo-ageing in a subject and contain as active ingredients plant extracts that comprise bisabolol (or synthetic bisabolo) and a Polygonum aviculare extract. In certain embodiments the cosmetic compositions of the present invention are in the form of a mist and is specially designed to reduce or prevent photo-ageing in a subject and contain as active ingredients plant extracts that comprise bisabolol (or synthetic bisabolo), a Polygonum aviculare extract, and Orya Satvia extract. Oryza Sativa Extract is made by processing rice grains. The process involves cleaning the rice, followed by milling to remove the bran. The bran is then subjected to extraction, often using solvents like water or alcohol to isolate the beneficial compounds. The extract is filtered to remove solids, and then concentrated through evaporation. Finally, the concentrated extract is purified and stabilized for use. In certain other embodiments the plant extract is an extract from rhizomes of Hedychium Coronarium, the butterfly ginger plant from Madagascar. (see Singh et al Molecules 2023, April; 28 (7) : 3278 – A comprehensive review on pharmacologically active phyto-constituents from Hedychium species – incorporated herein by reference) In certain other embodiments the plant extract is an extract from rhizomes of Hedychium Coronarium, the butterfly ginger plant from Madagascar added to the composition in an amount of about 0.0001-0.1 wt / wt%. In certain other embodiments the plant extract is an extract from rhizomes of Hedychium Coronarium, the butterfly ginger plant from Madagascar added to the composition in an amount of about 0.0001-0.1 wt / wt% (of the total composition), wherein the composition is in the form of a balm. In certain other embodiments the plant extract is an extract from rhizomes of Hedychium Coronarium, the butterfly ginger plant from Madagascar added to the composition in an amount of about 0.0001-0.1 wt / wt% (of the total composition), wherein the composition is in the form of a balm and further includes squalene, preferably between about 0.02-0.6 wt / wt%. In certain other embodiments the plant extract is an extract from rhizomes of Hedychium Coronarium, the butterfly ginger plant from Madagascar added to the composition in an amount of about 0.0001-0.1 wt / wt% (of the total composition), wherein the composition is in the form of a balm and further includes squalene, preferably between about 0.02-0.6 wt / wt%, and Helianthus Annus (Sunflower) seed oil, preferably between about 40-70 wt / wt%. In certain other embodiments the plant extract is an extract from rhizomes of Hedychium Coronarium, the butterfly ginger plant from Madagascar added to the composition in an amount of about 0.0001-0.1 wt / wt% (of the total composition), wherein the composition is in the form of a balm and further includes squalene, preferably between about 0.02-0.6 wt / wt%, Helianthus Annus (Sunflower) seed oil, preferably between about 40-70 wt / wt%, and panax ginseng root, preferably between about 0.00001- 0.1 wt / wt%. In certain embodiments the composition is in the form of a balm which is characterised with the following combination of ingredients: Helianthus Annuus (Sunflower) Seed Oil Euphorbia Cerifera Polyglyceryl-2 Synthetic Beeswax Microcrystalline Wax Octvidodecanol Butyrospermum Parki Butter Water Dipropylene Glycerin Bisabolol 1,2-Hexanediol Pentylene Glycol Squalane Polyglyceryl-10 Oleate Hydrogenated Lecithin Ethylhexylglycerin Adenosine Panax Ginseng Root Hedychium Sodium Hyaluronate In certain embodiments the composition is in the form of a balm which is characterised with the following combination of ingredients: H E P S M O B W D G B 1 P S P H E A P H S odium Hyaluronate 0.00001-0.01 In an embodiment the composition is for use in dermal conditioning of a subject. In an embodiment the dermal condition is minimising or reducing photo-aging in a subject. In an embodiment the dermal condition is minimising or reducing photo-aging in a subject, wherein the photo-aging is caused by exposure to blue light. In an embodiment the dermal condition is minimising or reducing photo-aging in a subject, wherein the photo-aging is caused by exposure to blue light, UV-A and UV-B light. In an embodiment the dermal conditioning is skin moisturising. In an embodiment the dermal condition is dry skin. In an embodiment the dermal conditioning is ageing. In an embodiment the dermal conditioning is skin hyperpigmentation. In an embodiment the dermal conditioning is skin-brightening. In an embodiment the dermal conditioning is acneic production. In another aspect the invention provides a cosmetic composition further comprises one or more of the following: emulsifying agent, sunscreen agent, stabilising agent, dispersing agent, suspending agent, thickening agent, and colouring agent. In an embodiment the invention provides cosmetic compositions which are non- inorganic-phosphate-buffered, that is to say that they do not contain an inorganic phosphate buffer. In one embodiment, the cosmetic compositions of the invention are topically applied to the skin directly or may be impregnated into a dressing which is subsequently applied to the skin (e.g., a face mask). Accordingly, in a further aspect the present invention provides dressings impregnated with the cosmetic compositions of the invention disclosed herein. In another aspect, the invention provides methods of treating a skin condition cosmetically including the step of applying to the skin of a subject the cosmetic composition as defined herein. In another aspect, the invention provides methods of dermal conditioning including the step of topically applying to the skin of a subject a cosmetic composition as defined herein. In a further aspect, the invention provides methods of reducing inflammation associated with a mild skin abrasion or skin redness including the step of topically applying to the skin of a subject a cosmetic composition as defined herein. In yet a further aspect, the invention encompasses uses of the cosmetic compositions and of the invention for topically delivering additional nutrients or agents (e.g., synergistic or supra additive agent) to the skin of a subject, for example an anti-inflammatory agent, such as at least one stem cell, synthetically derived small-molecule, peptide or genomic derived protein, or amino acid, anti-oxidant agent or hydroxy acids in the alpha, beta, poly and lipo classes (AHA, BHA, PHA, LHA), fermented microbiomic enhancement agents and dermal soothing agents. In preferred embodiments, the delivery is effected by topical administration. In certain embodiments of the above methods, the cosmetic compositions is applied to the skin and maintained at a temperature of between 4 and 40°C (e.g., 4 to 38oC) such that the surface of the skin is maintained in a suitable state and products remain stable as per cosmetic regulatory standards. Some of the advantages of the present inventive compositions include: ^ Protection against blue light exposure damage. ^ Protection against blue / UVA / UVB light exposure damage. ^ Encouragement of dermal healing and restoration of integrity via regulation of micro-circulation between dermal cells and connective tissue during metabolic action and promotion of epidermal cell growth. ^ Regeneration of elasticity via epidermal re-uptake. ^ Regulates sebum and oil production, anti-acneic and anti-congestive properties and suppression of comedone formation via downregulation of 5alpha reductase enzyme. ^ Further acneic regulation via stagnation of lipid peroxidation, anti-inflammatory activity and antimicrobial / antibacterial properties. ^ Stimulation of endogenous glycosaminoglycans, peptides and hyaluronic acid. Prevents denaturation and depletion of macromolecules. ^ Hydration and moisturisation throughout all levels of dermal matrix. ^ Protects against blue light damage of endo-peptides such as various types of collagen. ^ Mitigates post-inflammatory hyperpigmentation via transfer cycle of melanosomes from melanocytes into keratinocytes. ^ Anti-aging qualities through promotion of growth factors and other complementary molecules including elastin, flavin, filaggrin, involucrin, fibrillin etc. and denaturation or suppression of MMP activity. ^ Potent anti-inflammatory action, suppressing the TNF-alpha, NF-kb and other pathways, and reducing the release of inflammatory factors such as ILs and PEGs. ^ Calming and soothing action against irritated skin due to various aggressors or compromised skin condition ^ Reversal of irradiation in dermal cells via exposure to UV light – restores and reverses prior photodamage at the cellular level whilst offering photoprotective properties ^ Significant antioxidation ability and suppresses ROS, lipid peroxidation and other free radicals. Multiple scavenger agents of free radicals. ^ Humectant properties which draw water to the upper levels of the skin from the environment, emollience as well as occlusive properties of the moisturiser to seal in dermal conditioning treatments via product use. ^ Prevention of barrier damage and exposure to external aggressors due to an invisible film forming over the barrier, which in turn, significantly decreased trans- epidermal water loss. ^ Increases skin cell turnover rate without irritation / skin sensitivity or increased photosensitivity associated, maintaining anti-aging effect. Many of these factors occur at a microscopic level and therefore can be referred to as the microenvironment. Inside this microenvironment, factors are at play that influence whether the dermal condition can be ameliorated or becomes chronically stalled. It has been proven that the surface pH of a skin plays an important role in skin conditioning as it helps control infection and increase antimicrobial activity, oxygen release, angiogenesis, protease activity, and bacterial toxicity. Therefore, the pH value of the skin affects the regular cellular events. The compositions / formulations disclosed herein may be utilised in the following products: Serum – inclusive of all agents which address embodiments related to dermal conditioning above, suitable for all skin types, all skin concerns and featuring optionally including proanthocyanidin agents, significant antioxidants and age defying components which reinforce cellular and mitochondrial integrity. Moisturiser – may include a blend of at least 4 super oil compounds to create a micro- emulsion, predominantly focusing on restoration of the lipid component of the bilayer and utilising innovative techniques, such as sonication, to improve and increase endogenous ceramide and lipid synthesis within the dermal tissue. Essence (this may include a blend of ferments like galactomyces or mugwort etc.). Essences promote the absorption of products to follow, through skin dampening and relative activity of the stratum corneum, and offers non-viscous, easily absorbed and highly beneficial dermal conditioning components as a first step following a cleanse. Cleanser – simple hydrating formulation without stripping the skin, and may also contain yerba mate, and centella water etc. Cream cleanser preferably or innovative surfactant technology without stripping the skin. Hydrogel mask covering face and neck which may be impregnated with the water-based compositions of the present invention. Eye creams - compositions which may include further ingredients that firm, hydrate, soothe and reduce puffiness and dark circles around the eyes. Body lotions / balms –compositions which may be is lightweight, easier to absorb and a little lower on the hydration scale. Balms- the compositions may be mixed with balm (such as a lip balm) forming ingredients such are beeswax, sunflower oil, shea butter, vitamin E and jojoba. Some balms may include other ingredients such as petroleum jelly, lanolin, dyes, flavour, fragrances oils and sunscreen actives as mentioned herein. Lipsticks- the compositions may be added to lipstick ingredients such as waxes (such as beeswax), oils, and colour pigments. Mists- these compositions typically consist of a mixture of water, a small amount of alcohol, and essential oils / fragrance ingredients, and may also include active ingredients that support moisturisation or hydration of the skin. In certain other embodiments and with reference to all aspects the ionic conductivity of the compositions of the invention is preferably comparable to that of human serum, namely 12.0±0.3 mS cm-1and as such maintains the ionized status of the cell membrane and activities of enzymic moieties. Thus in accordance with the above, the compositions of the present invention may include further quantities of electrolytes such as salts (Ca2+, Mg2+, K+, Na+, Cl- etc) whereby the compositions are isosmotic to human serum (ca.290 mOsmoles / L). Furthermore, the inclusion of levels of glycerol, in the composition may also contribute to osmotic buffering at the dermal interface. Information regarding benefits of certain ingredients used in embodiments of compositions of the present invention: 1,3-Propanediol - Propanediol is a natural alternative and used to replace the bad mouth feel of propylene glycol. It is produced sustainably from corn sugar and it's Ecocert approved. It can be used to improve skin moisturization, as a solvent, to boost preservative efficacy or to influence the sensory properties of the end formula. Butylene glycol – a colourless, syrupy liquid with nice feel. Its main job is to be a solvent for the other ingredients. Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin. Hydrolyzed rhodophycea - a type of red algae that helps improve skin’s hydration and ability to look healthy while also being a good source of antioxidants. Research has shown the antioxidants in many types of algae, including red algae, help offset the oxidative damage UV-B light exposure triggers. Red algae is a rich source of carrageenan, which in compositons serves as a natural thickening and gelling ingredient. The structure of carrageenan closely resembles glycosaminoglycans, which are a key part of skin’s barrier. In this capacity, the carrageenan in red algae can help deliver other ingredients throughout skin’s uppermost layers. Along with carrageenan, red algae is a source of plant cholesterol, whose fatty acid compounds benefit skin. Panax Ginseng Root Extract - A traditional Korean medicine used for more than 2000 years. Regarding skin care, it aims to enhance skin nutrition and metabolism as a result of improving blood circulation. It also contains biologically active components referred to as ginseng saponins (ginsenosides) that have potent antioxidant properties. Glycerin - A natural moisturizer that’s also in our skin. A common, safe, effective and cheap molecule used for more than 50 years. Not only a moisturizer but also keeps the skin lipids between our skin cells in a healthy (liquid crystal) state, protects against irritation, helps to restore barrier. Effective from as low as 3% with even more benefits for dry skin at higher concentrations up to 20-40%. High-glycerin moisturizers are beneficially used for treating severely dry skin. Xanthan Gum – A thickener and emulsion stabilizer. If the product is too runny (e.g., serum), a little xanthan gum will make it more gel-like (e.g., cream). Can be used with other thickeners and so-called rheology modifiers (i.e., helper ingredients that adjust the flow and thus the feel of the formula). The typical use level of Xanthan Gum is below 1%wt / wt, it is usually in the 0.1-0.5%wt / wt range. Xanthan gum is all natural, a chain of sugar molecules (polysaccharide) produced from individual sugar molecules (glucose and sucrose) via fermentation. It’s approved by Ecocert and also used in the food industry (E415). Lecithin- An ingredient that can be found in all cell membranes. In cosmetics it has a few different roles: it's an emollient and water-binding ingredient but it's also an emulsifier and can be used for stabilization purposes. It's also often used to create liposomes. Pullulan - Versatile skin care ingredient known for it's hydration and antioxidant properties. Functions well as a “carrier” to deliver active ingredients where they need to go. Has potential to help strengthen skin’s microbiome and can provide temporary mechanical support for skin’s underlying structures. Continually being studied for its many therapeutic, film-forming benefits for skin. Sclerotium gum - A naturally derived, sugar-based ingredient. Produced by the fermentation of the Sclerotium rolfsii fungus. Functions as a thickener and stabilizer in cosmetics compositions. Silica - Natural ingredient found in clays as well as in parts of plants and animals Used as an absorbent powder and thickener in cosmetics and can enhance the absorption of ingredients and serve as a drug delivery system. Is also FDA-approved as a food additive. Sodium stearoyl glutamate- is a synthetic or animal-derived ingredient that is added to cosmetics to condition skin or work as an emulsifier, keeping oil-and-water formulas blended. Sodium benzoate - Salt of benzoic acid, which is found naturally in foods like cranberries. Used as a preservative in both cosmetics and food products Deemed safe as used in cosmetics and is a white, crystalline solid in its raw form. Sodium Hyaluronate - Salt form of hyaluronic acid and good skin-replenishing ingredient. One gram can hold up to six litres of water. More readily absorbed into skin than hyaluronic acid. Available in different molecular weights for controlled penetration. Lactic acid - Can be extracted from milk or synthetically made. Exfoliates the surface of skin and has hydrating properties and strengthens skin’s barrier. Helps positively influence skin’s microbiome. Benzyl alcohol - An organic alcohol that can be found naturally in some fruits. Serves chiefly as a preservative in cosmetics products and is considered one of the least sensitising preservatives. Deemed safe for use in concentrations up to 5%wt / wt of the total composition. Dehydroacetic acid - is a synthetic preservative used in amounts of 0.6%wt / wt or less where it’s proven to be safe and effective. Dehydroacetic acid is characterized as a white to cream crystalline powder. Sometimes its salt form (known as sodium dehydroacetate) is used, as it is more soluble in certain types of cosmetic formulas. Dehydroacetic acid is most effective as an anti-fungi ingredient. The invention envisages that specific sub-components of the solutions of the invention can be used individually or in any combination. Particular embodiments of the invention are described below by way of the following examples. The examples are provided to illustrate embodiments of the invention but are not to be considered as limiting in any way. Examples Formulation Examples: Formulation Example 1: Ingredient Purpose P h s e g n P n o P g S S S s S S n Dehydroacetic Acid Preservatives, prevent growth of microorganisms Formulation Example 2: Formula: Serum Raw Material (RM) Name followed by INCI Breakdown Percent in Percent in 1 I S L S P S I I Butylene Glycol 39.5 0.395 Hydrolyzed Rhodophyceae Extract 0.5 0.005 I L I P S I 1 Formulation Example 3: Ingredients: Aqua q.s; 1, 3-Propanediol; Buddleja Officinalis Flower Extract, Blue light protection; Butylene glycol; Hydrolyzed Rhodophyceae Extract / red algae; Panax Ginseng Root Extract; Glycerin; Xanthan Gum; Lecithin; Pullulan; Sclerotium Gum Silica; Sodium Steraroyl Glumate; Sodium benzoate; Sodium Hyaluroante; Lactic acid; Benzyl alcohol; and Dehydroacetic acid. Formulation Example 4: This formulation uses an extract from the rhizomes of Hedychium Coronarium, the butterfly ginger plant from Madagascar. The formulation provides protection to the skin against blue light, UV, Infra-red (IR), heat, air pollution and chronological aging. Also realised is improvement in skin brightness whereby the subject's complexion is more radiant and homogeneous. Without wishing to be bound by any particular theory this extract regulates the autophagy (the cleaning and recycling process of cells' components through lysosomes) under blue light and UVA, reduces ROS under pollution, and protects mitochondria for an energizing effect. The formulation below is prepared in the form of a balm: Function CAS NO. %(w / w) Helianthus Annuus Skin-Conditioning Agent 8001-21-6 63.9470000 (Sunflower) Seed Oil Euphorbia Cerifera Viscosity Increasing Agent 8006-44-8 7.0000000 (Candelilla) Wax Polyglyceryl-2 Triisostearate Skin-Conditioning Agent 120486- 24-0 Synthetic Viscosity Increasing Agent 71243-51- 6.0000000 1 Microcrystalline Viscosity Increasing Agent 63231-60- 5.0000000 7 O ctvidodecanol Skin-Conditioning Agent 5333-42-6 5.0000000 Butyrospermum Parki (Shea) Skin-Conditioning Agent 91080-23- 3.0000000 Dipropylene Glycol Solvent 110-98-5 0.7000000 Glycerin Humectant 56-81-5 0.6006860 Bisabolol Skin-Conditioning Agent 23089-26- 0.5000000 1 1,2-Hexanediol Solvent 6920-22-5 0.2000400 Pentylene Glycol Skin-Conditioning Agent 5343-92-0 0.1960000 Squalane Skin-Conditioning Agent 111-01-3 0.1000000 10 Oleate Surfactant - 9007-48-1 0.1000000 11-3 Ethylhexylglycerin Skin-Conditioning Agent 70445-33- 9 Adenosine Skin-Conditioning Agent 58-61-7 0.0400000 Panax Ginseng Root Extract Skin-Conditioning Agent 72480-62- 0.0000500 7 H edychiu Co o a iu Root Ski Co ditio i g Age t Extract blue light, UV, Infra-red (IR) protectant Sodium Hyaluronate Skin-Conditioning Agent 9067-32-7 Formulation Example 5: In this formulation (designed as a mist) bisabolol is used as new anti-pollution and anti- blue light active, extracted through an extraction process from three varieties of rice: black, red and brown. It is biomimetic, eco-designed, 100% vegetal, locally-sourced, totally safe and COSMOS-certified. The formulation below is prepared in the form of a mist: Alcohol, Homosalate, Octocrylene, Butyloctyl Salicylate, Ethylhexyl Salicylate, Dibutyl Adipate, Butyl Methoxydibenzoylmethane, Fragrance, Glycine Soja (Soybean) Oil, Tocopheryl Acetate, Glycerin, Polyglyceryl-3 Diisostearate, Oryza Sativa Germ Extract, Oryza Sativa Extract, Bisabolol, Water, Ceramide NP, and Polygonum Aviculare Extract. Without wishing to be bound by any particular theory the inventors consider that the addition of Bisabolol provides the following benefits:^effectively protects cells from urban pollution and blue light, and boosts the human defense system,^regulates hyperpigmentation caused by blue light from technical device screen’s glow,^effectively boosts cell repair, and protects DNA and other cellular components of damaging effects induced by urban pollutants and blue light, and^is exceptionally efficient in both preventing and repairing ROS formation and damages induced by urban pollution and blue light. In certain embodiments the formulation includes bisabolol is an amount of about 0.2-2% wt / wt % of the total composition (for instance, about 0.5% wt / wt). In certain embodiments Ceramide may be add at about 2-10% such as about 6% wt / wt%. Testing Examples: The ability for the compositions to protect again blue light can be assessed based on the following methods: ^ New Sunscreens confer improved protection for photosensitive patient in the blue light region. Moseley, H, et al British Journal of Dermatology 145, 789- 794. ^ New In Vitro method allowing the Blue Light Protection assessment of sunscreens. Delmour. E et al Euro Cosmetics 10-2017. Sample Preparation The test material may be applied to PMMA plates at an application rate of 1.3mg / sq cm. Samples are allowed to dry in the dark at 35oC for 15 minutes. Spectral Measurements The spectral transmission is measured using a Shimadzu UV Spectrophotometer at 1 nm intervals over the spectral range was 290 to 750 nm. Photosensitivity Protection Factor (PPF) may be determined by applying the formula: PPF (∫ Eλ Sλ Δλ) / (∫ Eλ SλTλ Δλ) Eλ = Photosensitivity action spectrum Sλ = Spectral irradiance Tλ = Spectral transmission of the sunscreen Δλ = Wavelength step 1nm Percentage Blue Light Protection (percent blue light stopped by the product) (380nm – 500nm) is calculated with the following formula: % Transmittance BL = ∑T 380nm to 500nm / n %BL = 100 - % Transmittance BL. Blue Light Critical Wavelength may be calculated with the following formula: BL-CW = 0.9 x 290nm∫ 500nm A1BL . d where A1BL is the mean of the absorbance measurements with an interval of 1nm Visible Light Protection % Transmittance Visible Light = ∑T 380nm to 700nm / n % Visible Light stopped = 100 - % Transmittance Visible Light. % HEV Protection (percent high energy visible light stopped by the product) (400nm – 500nm) % Transmittance HEV = ∑T 400nm to 500nm / n % HEV stopped = 100 - % Transmittance HEV In vitro testing Reduction of free radicals Looking at ROS production (RFU, relative fluorescence units) vs ROS production of Keratinocytes , with exposure to blue light (7mW / cm2for 20mins), seeing a 20-40% reduction.

Claims

THE CLAIMS DEFINING THE INVENTION ARE AS FOLLOWS:

1. A water based cosmetic composition comprising: (i) about 0.03-6% wt / wt of a plant extract which comprises both verbascoside and echinacoside; and (ii) about 1-4% wt / wt of 1,3-propandiol.

2. A composition according to claim 1 which comprises from 85-96% wt / wt water content.

3. A composition according to claim 1 or 2 wherein the plant extract which comprises both verbascoside and echinacoside is selected from one or more of the following: Buddleja Officinalis Flower Extract, Buddleija davidii, Australian Red Centre Lime, Banksia, Blue Cypress, Davidon Plum, Desert Lime, Emu Apple / Muntries, Finger Lime Caviar, Flame Tree, Flannel Flower, Kakadu Plum, Kangaroo Paw, Karkalla, Lemon Aspen, Lemon Myrtle, Lilli-Pilli-Riberry, Mountain Pepper Berry / Leaf, Native River Mint, Native Seaweed-Tasmania Kelp, Native Snowflower / Tea Tree, Pink Ice Finger Lime, Quandong, Queen Garnet, Red Champagne Finger Limes, Rosella, Silky Oil Grass, Snake Vine, Strawberry Gum, Sunrise Lime, Tasmania Blue Gum, Tasmania Lavender, Waratah and Waxflower.

4. A composition according to claim 1 or 2 wherein the plant extract which comprises both verbascoside and echinacoside is selected from one or more of the following: Buddleja Officinalis Flower Extract, and Buddleija davidii.

5. A composition according to claim 1 or 2 wherein the plant extract which comprises both verbascoside and echinacoside is Buddleja Officinalis Flower Extract.

6. A composition according to anyone of claims 1 to 5 wherein the plant extract is characterised with from about 5-25% wt / wt of verbascoside, based on the dry weight of the plant extract.

7. A composition according to anyone of claims 1 to 5 wherein the plant extract is characterised with from about 1-10% wt / wt of echinacoside, based on the dry weight of the plant extract.

8. A composition according to anyone of claims 1 to 5 wherein the plant extract is characterised with from about 5-25% wt / wt of verbascoside, and about 1-10% wt / wt of echinacoside, based on the dry weight of the plant extract.

9. A composition according to anyone of claims 1 to 8 wherein the composition is characterised as having a pH of from about 3 to about 6.

10. A composition according to anyone of claims 1 to 9 wherein the composition comprises the plant extract with both verbascoside and echinacoside at about 0.03, 0.05, 0.1, 0.4, 0.8, 1.0, 1.2, 1.3, 1.5, 1.7, 1.9, 2.1, 2.2, 2.3, 2.5, 2.7, 2.9, 3.2, 3.4, 3.6, 3.8, 4.0, 4.2, 4.4, 4.6, 4.8, 5.0, 5.2, 5.4, 5.6, 5.8, or about 6.0% wt / wt or any range in between these two figures.

11. A composition according to anyone of claims 1 to 10 wherein the composition comprises 1,3-propandiol at about 1.0, 1.2, 1.3, 1.5, 1.7, 1.9, 2.1, 2.2, 2.3, 2.5, 2.62.7, 2.8 2.9, 3.0, 3.2, 3.3, 3.5, 3.7, 3.9, or about 4.0 or any range in between these two figures.

12. A composition according to anyone of claims 1 to 11 wherein the compostion further comprises hyaluronic acid or a salt thereof, for instance, sodium hyaluronate.

13. A composition according to claim 12 wherein the hyaluronic acid or a salt thereof is in an amount of about 0.05-0.5% wt / wt.

14. A composition according to anyone of claims 1 to 13 wherein the compositions further comprise one or more thickening or gelling agents.

15. A composition according to claim 14 wherein the one or more thickening or gelling agents may be selected from agar, carrageenan, arrowroot, gum Arabic, gellan gum, guar gum, xanthan gum, alginic acid, sodium alginate, hypromellose, Tragacanth, Lecithin (also an emulsifier), Sclerotium Gum, and Pullulan (film forming compound, also functions in moisture-retention).

16. A composition according to claim 1 comprising the following (wt / wt%): W 9095% 1 S S S P S S 1 B17. A composition according to anyone of claims 1 to 16 wherein the compositions further include one or more of UV-A and / or UV-B cosmetically acceptable filters (sunscreen agents) such as octocrylene, ecamsule, dioxybenzone, bisoctrizole, ethylhexyl triazone, avobenzone, zinc oxide, iron oxide, titanium oxide, oxybenzone, and octyl methoxycinnamate.

18. A cosmetic composition comprising: (i) about 0.03-4% wt / wt of pure verbascoside and / or echinacoside; and (ii) about 1-4% wt / wt of 1,3-propandiol, and wherein the composition is characterised as having a pH of from about 3 to about 6.

19. A cosmetic composition according to claim 18 wherein further comprises one or ingredients as defined in anyone of claims 11, 12, 13, 14, 15 or 17.

20. A cosmetic composition according to anyone of claims 1 to 19 in the form of a serum.

21. A cosmetic composition according to anyone of claims 1 to 19 in the form of a cream.

22. A cosmetic composition in the form of a mist when used to reduce or prevent photo-ageing in a subject wherein said composition contains a plant extract that comprises bisabolol, or synthetic bisabolo.

23. A cosmetic composition according to claim 22 wherein said composition contains a plant extract that comprises bisabolol (or synthetic bisabolo) and a Polygonum aviculare extract.

24. A cosmetic composition according to claim 22 or claim 23 wherein said composition contains a plant extract that comprises bisabolol (or synthetic bisabolo), a Polygonum aviculare extract, and an Orya Satvia extract.

25. A cosmetic composition according to anyone of claims 22 to 24 wherein said composition contains plant extracts that comprise bisabolol (or synthetic bisabolo), a Polygonum aviculare extract, and an Orya Satvia extract, and preferably Oryza Sativa Germ Extract, and Oryza Sativa Extract.

26. A cosmetic composition according to anyone of claims 22 to 25 wherein said composition which is the form of a mist which comprises: Alcohol, Homosalate, Octocrylene, Butyloctyl Salicylate, Ethylhexyl Salicylate, Dibutyl Adipate, Butyl Methoxydibenzoylmethane, Fragrance, Glycine Soja (Soybean) Oil, Tocopheryl Acetate, Glycerin, Polyglyceryl-3 Diisostearate, Oryza Sativa Germ Extract, Oryza Sativa Extract, Bisabolol, Water, Ceramide NP, and Polygonum Aviculare Extract.

27. A cosmetic composition in the form of a balm when used to reduce or prevent photo-ageing in a subject wherein said composition contains a plant extract that comprises an extract from rhizomes of Hedychium Coronarium.

28. A cosmetic composition according to claim 27, wherein the plant extract from rhizomes of Hedychium Coronarium, is added to the composition in an amount of about 0.0001-0.1 wt / wt%.

29. A cosmetic composition according to claim 27 or claim 28 further including squalene, preferably between about 0.02-0.6 wt / wt%.

30. A cosmetic composition according to anyone of claims 27 to 29 further including Helianthus Annus (Sunflower) seed oil, preferably between about 40-70 wt / wt%.

31. A cosmetic composition according to anyone of claims 27 to 30 further including panax ginseng root, preferably between about 0.00001- 0.1 wt / wt%.

32. A cosmetic composition according to anyone of claims 27 to 31 in the form of a balm which is characterised with the following combination of ingredients:Helianthus Annuus (Sunflower) Seed Oil Euphorbia Cerifera (Candelilla) Wax Polyglyceryl-2 Triisostearateor%33. A method of dermal conditioning of a subject said method including the step of applying to the skin on said subject an effective amount of a composition according to anyone of claims 1 to 32.

34. A method according to claim 33 wherein the dermal conditioning is minimising or reducing photo-aging in a subject.

35. A method according to claim 33 wherein the dermal conditioning is minimising or reducing photo-aging in a subject, wherein the photo-aging is caused by exposure to blue light.

36. A method according to claim 33 wherein the dermal conditioning is minimising or reducing photo-aging in a subject, wherein the photo-aging is caused by exposure to blue light, UV-A and UV-B light.

37. A method according to claim 33 wherein the dermal conditioning is skin moisturising.

38. A method according to claim 33 wherein the dermal conditioning is dry skin.

39. A method according to claim 33 wherein the dermal conditioning is ageing.

40. A method according to claim 33 wherein the dermal conditioning is skin hyperpigmentation.

42. A method according to claim 33 wherein the dermal conditioning is acneic production.

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