Control system for multiple light sources for photodynamic therapy
Through the multi-digit light source control system based on a microcontroller, the limitations of existing light therapy equipment in adjusting laser parameters are solved, and the simultaneous irradiation of multi-wavelength lasers and the precise adjustment of laser energy and spot size are achieved, improving the efficiency of light therapy and standardization of experiments.
Patent Information
- Application Number
- PCT/CN2024/123893
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-12-11
- Filing Date
- 2024-10-10
- Publication Date
- 2025-03-06
AI Technical Summary
Existing phototherapy equipment has limitations in adjusting laser parameters, and it is impossible to achieve simultaneous irradiation of multiple wavelength lasers, and the adjustment accuracy of light intensity and spot size is low, which is not conducive to the standardization of phototherapy experiments.
The multi-light source control system based on a microcontroller is adopted, including a matrix laser source, a 3-axis stepper motor, a matrix keyboard and an OLED display. The multi-channel switching power supply and laser source are controlled through the microcontroller to adjust and accurately irradiate multi-wavelength lasers.
The simultaneous irradiation of multi-wavelength lasers is achieved, which improves the adjustment accuracy of laser energy and spot size, adapts to different experimental needs, and improves the efficiency of phototherapy and standardization of experiments.
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Figure CN2024123893_06032025_PF_FP_ABST
Abstract
Description
A complex light source control system for photodynamic therapy Technical Field
[0001] The present invention relates to the field of medical light sources, and in particular to a multiple light source control system for photodynamic therapy. Background Art
[0002] Photodynamic therapy (PDT), a non-invasive, side-effect-free physical therapy, irradiates photosensitizers and specific tissues with light of varying wavelengths, triggering a series of biological effects on molecules within the tissues, such as cytochromes and mitochondria. These biological effects promote wound healing, reduce inflammation and relieve pain, alleviate muscle fatigue, and promote tissue repair. Therefore, photon therapy is widely used in the treatment of dermatology, surgery, rehabilitation, oncology, and other medical conditions. For example, patent application number 202010893496.5 discloses a treatment method and a photodynamic therapy system based on a photodynamic therapy system. The method comprises: obtaining a fluorescence image generated when a photosensitizer is irradiated on the tissue to be treated; calculating the fluorescence image using a fluorescence image processing algorithm to determine overexposed and underexposed areas in the fluorescence image; analyzing the overexposed and underexposed areas of the fluorescence image using a preset convolutional neural network model to determine the required excitation light dose for each point in the fluorescence image; and generating a therapeutic light intensity based on the required excitation light dose for each point in the fluorescence image.
[0003] The above patent discloses a scheme for photodynamic therapy, but a very important aspect of photodynamic therapy is the control of the light source. Photodynamic therapy has important application value in basic experimental research, and its effect is affected by factors such as laser wavelength, energy and spot size. Existing phototherapy equipment has limitations in adjusting laser parameters and cannot achieve simultaneous irradiation of multiple wavelength lasers. At the same time, the adjustment accuracy of light intensity and spot size is low, which is not conducive to the standardization of phototherapy experiments. Therefore, the present application provides a multiple light source control system for photodynamic therapy based on a single-chip microcomputer. Summary of the Invention
[0004] The purpose of the present invention is to overcome the deficiencies of the prior art and to provide a single-chip microcomputer-based multiple light source control system for photodynamic therapy, which is used to adjust and control multiple light sources.
[0005] In order to achieve the above-mentioned purpose, the technical solution adopted by the present invention is: a multiple light source control system for photodynamic therapy, including a single-chip microcomputer, a matrix laser source, a multi-way switching power supply, a 3-axis stepping motor, and a matrix keyboard. The multi-way switching power supply outputs multiple types of power supply voltages for the single-chip microcomputer, the 3-axis stepping motor, and the matrix laser power supply; the input end of the single-chip microcomputer is connected to the matrix keyboard for outputting adjustment parameters; the output end of the single-chip microcomputer is respectively connected to the 3-axis stepping motor and the matrix laser power supply for controlling the matrix laser power supply and the 3-axis stepping motor.
[0006] The system also includes an OLED display and a buzzer module. The output end of the single-chip microcomputer is connected to the OLED display and the buzzer module respectively, and is used to control the OLED display to realize the output state of the matrix laser light source. The buzzer is used to send a reminder signal to the light source output.
[0007] The single chip microcomputer is an STM32 series single chip microcomputer.
[0008] The STM32 series microcontroller includes multiple chip units U1A, U1B, U1C, U1D, and U1E, and its model is STM32 F103ZET6 microcontroller.
[0009] A crystal oscillator Y1 is connected in series between pins 8 and 9 of the microcontroller U1B, and a crystal oscillator Y2 is connected in series between pins 23 and 24 of the microcontroller U1D. Pins 8 and 9 are grounded via capacitors C4 and C5 respectively. The reset pin 25 of the microcontroller U1 is connected to the ground and the power supply voltage via capacitor C8 and resistor R2 respectively. Pin 32 of the chip UIF is connected to the power supply voltage via resistor L1 and grounded via C9.
[0010] The PB8 pin of the microcontroller U1A is connected to the BEEP pin, the input terminal of the buzzer module. The PB8 pin of the microcontroller U1A is connected to the b pin of the transistor Q1 through the resistor R18. The c pin of the transistor Q1 is connected to the power supply voltage through the buzzer BZ1. The e pin of the transistor Q1 is grounded. The b pole and the e pole of the transistor Q1 are connected.
[0011] The multi-way switching power supply is integrated with a voltage stabilizing chip, which is used to convert the input voltage into the 3.3V voltage required by the single chip microcomputer for power supply.
[0012] The matrix keyboard module is a 4*4 Key module connected to PA0-PA7 of the microcontroller U1A, and the matrix function 4*4 is realized through the staggered connection of PA0-PA7 pins; the PA0 pin of the microcontroller U1A is connected to the resistor R7 and the power supply 3.3V, the PA1 pin is connected to the resistor R8 and the power supply 3.3V, the PA2 pin is connected to the resistor R9 and the power supply 3.3V, the PA4 pin is connected to the resistor R12 and the power supply 3.3V, the PA5 pin is connected to the resistor R13 and the power supply 3.3V, the PA6 pin is connected to the resistor R15 and the power supply 3.3V, and the PA4 pin is connected to the resistor R17 and the power supply 3.3V.
[0013] The stepper motor control is achieved by complementary dead zone control of the PB13-15 pins and PA9-PA11 pins of the microcontroller U1A. The PB13 pin of the microcontroller U1A is connected to the resistor R19 and connected to the x-axis control end of the 3-axis stepper motor. The PB14 pin of the microcontroller U1A is connected to the resistor R20 and connected to the y-axis control end of the 3-axis stepper motor. The PB15 pin of the microcontroller U1A is connected to the resistor R22 and connected to the z-axis control end of the 3-axis stepper motor.
[0014] For laser control, PB0 of the microcontroller U1A is connected to resistor R23 and connected to the first control terminal of the matrix laser power supply; PB1 of the microcontroller U1A is connected to resistor R24 and connected to the second control terminal of the matrix laser power supply; PB4 of the microcontroller U1A is connected to resistor R25 and connected to the third control terminal of the matrix laser power supply; PB5 of the microcontroller U1A is connected to resistor R26 and connected to the fourth control terminal of the matrix laser power supply; PB6 of the microcontroller U1A is connected to resistor R27 and connected to the fifth control terminal of the matrix laser power supply; PB7 of the microcontroller U1A is connected to resistor R29 and connected to the sixth control terminal of the matrix laser power supply; PB8 of the microcontroller U1A is connected to resistor R30 and connected to the seventh control terminal of the matrix laser power supply; PB9 of the microcontroller U1A is connected to resistor R31 and connected to the eighth control terminal of the matrix laser power supply; PB10 of the microcontroller U1A is connected to resistor R33 and connected to the ninth control terminal of the matrix laser power supply.
[0015] The advantages of the present invention are:
[0016] 1. It can realize the convenience of biochemical experiment operation and can achieve precise laser irradiation without manual operation.
[0017] 2. Through the matrix keyboard input and PWM algorithm, multi-wavelength laser irradiation can be achieved simultaneously. At the same time, the number of pulse signals can be controlled within a certain range to adjust the laser energy and spot size to adapt to different experimental needs and meet the basic experimental requirements of different occasions.
[0018] 3. Ability to stimulate multiple molecules in biological samples independently or simultaneously, improving experimental efficiency.
[0019] 4. The output status is displayed on the OLED screen, which is easy to operate and convenient for the operator.
[0020] 5. Developed using a single-chip microcomputer, it is low cost and easy to implement.
[0021] The advantages of the multiple light source control system provided in this embodiment mainly come from the specific design and functions of the system:
[0022] 1. Convenient biochemical experimental operation: This advantage is due to the system's ability to automate and precisely administer laser irradiation, reducing the need for manual operation. This automation is crucial in photodynamic therapy because it ensures consistent and accurate treatment. Advances in automation technology have made PDT more efficient and controllable.
[0023] 2. Simultaneous Multi-Wavelength Laser Irradiation: Through matrix keyboard input and PWM algorithms, this system can simultaneously irradiate multiple laser wavelengths. This is extremely important because different wavelengths of light are required to activate different photosensitizers and induce different biological effects. The ability to use multiple laser wavelengths simultaneously provides greater flexibility and effectiveness in treatment.
[0024] 3. Adjusting Laser Energy and Spot Size: The system can control the number of pulses within a certain range, thereby adjusting the laser energy and spot size. This is crucial for adapting to diverse experimental needs, as different treatments and experiments may require different light intensities and sizes. Precise control of these parameters can improve treatment efficacy and minimize damage to surrounding healthy tissue.
[0025] 4. Independently or simultaneously stimulate multiple molecules in biological samples: This capability improves experimental efficiency and flexibility. In PDT, precise control of the light source allows for targeted stimulation of specific molecules, thereby improving the targeting and effectiveness of treatment.
[0026] 5. OLED screen displays output status, simplifying operation: The OLED display in the system makes operation more intuitive and convenient. This user interface design allows the operator to easily control and monitor the treatment process, improving the safety and accuracy of the operation.
[0027] 6. Developed with a single-chip microcomputer, it is low-cost and easy to implement: Using a single-chip microcomputer as the control core means that the system is cost-effective and easy to implement. The use of single-chip microcomputers makes such complex control systems more feasible, even in resource-limited environments. BRIEF DESCRIPTION OF THE DRAWINGS
[0028] The following is a brief description of the contents and symbols in the drawings of the present invention:
[0029] FIG1 is a schematic diagram of the principle structure of the present invention;
[0030] FIG2 is a schematic diagram of the U1A and U1B pins of the STM32 single-chip microcomputer of the present invention;
[0031] FIG3 is a schematic diagram of the U1C, U1D, and U1E pins of the STM32 microcontroller of the present invention;
[0032] FIG4 is a schematic diagram of the peripheral circuit of the single chip microcomputer of the present invention. DETAILED DESCRIPTION
[0033] The specific implementation of the present invention will be further explained in detail below by describing the best embodiment with reference to the accompanying drawings.
[0034] As shown in FIG1 , this embodiment provides a complex light source control system for photodynamic therapy, including a single-chip microcomputer, a matrix laser source, a multi-channel switching power supply, a 3-axis stepper motor, a matrix keyboard, an OLED display, and a buzzer module;
[0035] The multi-channel switching power supply outputs multiple types of power supply voltages for microcontrollers, 3-axis stepper motors, and matrix laser power supplies. It can output 3.3V to power the microcontroller, 12V to power the stepper motor, and 24V to power the matrix laser light source.
[0036] The MCU's input is connected to a matrix keyboard for outputting adjustment parameters. Its outputs are connected to a three-axis stepper motor and a matrix laser power supply for controlling them. The MCU's outputs are also connected to an OLED display and a buzzer module for controlling the OLED display's response to the matrix laser light source's output state. The buzzer is used to signal the light source's output.
[0037] A multi-channel switching power supply is the system's power support core, providing appropriate voltages to various components. The STM32 microprocessor receives a 3.3V power supply to ensure proper operation of its logic processing and control functions; the matrix laser source receives a 24V power supply for laser emission; and the three-axis stepper motor receives a 12V power supply for precise movement.
[0038] STM32 microcontroller: As the brain of the system, it is responsible for receiving input parameters and controlling the three-axis stepper motor to achieve precise positioning of the laser light source. At the same time, it adjusts the light intensity and spot size of the matrix laser source to meet different treatment needs.
[0039] Matrix keyboard: used for manual input of control parameters, such as laser wavelength, power, and spot size. These parameters will be read and executed by the STM32 microprocessor, which then controls the three-axis stepper motor to achieve precise positioning of the laser light source and adjust the light intensity and spot size of the matrix laser source.
[0040] OLED display and buzzer: used to feedback system status and operation results. The display can show the current operating parameters and status, and the buzzer may be used for alarm or to provide operation feedback.
[0041] Three-axis stepper motor: According to the instructions of the STM32 microprocessor, the laser light source is accurately moved to the specified position to achieve precise irradiation. The position of the light source is achieved through the drive control of the three-axis stepper motor. The light source can be set on a movable track and then driven by the three-axis stepper motor through the three-axis drive output to drive the light source through the transmission mechanism and other mechanical mechanisms to move the laser light source to the specified position.
[0042] Matrix laser source: Receives control signals from a microprocessor and adjusts the output of the light source based on input parameters, which may include wavelength, intensity, and spot size, to meet specific experimental or therapeutic needs.
[0043] The following application will use one of the ST32 series microcontrollers to control the above modules in detail as follows:
[0044] As shown in Figure 2-4, the STM32 series microcontroller includes multiple chip units U1A, U1B, U1C, U1D, and U1E. The model is the STM32 F103ZET6 microcontroller. Crystal oscillator Y1 is connected in series between pins 8 and 9 of microcontroller U1B. Crystal oscillator Y2 is connected in series between pins 23 and 24 of microcontroller U1D. Pins 8 and 9 are connected to ground via capacitors C4 and C5, respectively. Reset pin 25 of microcontroller U1 is connected to ground and the power supply voltage via capacitor C8 and resistor R2, respectively. Pin 32 of chip UIF is connected to the power supply voltage via resistor L1 and ground via C9.
[0045] Pin PB8 of microcontroller U1A is connected to the buzzer module's input pin, BEEP. Pin PB8 of microcontroller U1A is connected to pin b of transistor Q1 through resistor R18. Pin c of transistor Q1 is connected to the power supply voltage via buzzer BZ1, and pin e of transistor Q1 is grounded. The b and e terminals of transistor Q1 are connected. The multi-channel switching power supply integrates a voltage regulator chip, which converts the input voltage into the 3.3V required by the microcontroller for power supply.
[0046] The matrix keyboard module is a 4*4 Key module connected to PA0-PA7 of the microcontroller U1A, and the matrix function 4*4 is realized through the staggered connection of PA0-PA7 pins; the PA0 pin of the microcontroller U1A is connected to the resistor R7 and the power supply 3.3V, the PA1 pin is connected to the resistor R8 and the power supply 3.3V, the PA2 pin is connected to the resistor R9 and the power supply 3.3V, the PA4 pin is connected to the resistor R12 and the power supply 3.3V, the PA5 pin is connected to the resistor R13 and the power supply 3.3V, the PA6 pin is connected to the resistor R15 and the power supply 3.3V, and the PA4 pin is connected to the resistor R17 and the power supply 3.3V.
[0047] The stepper motor control is achieved by complementary dead zone control of the PB13-15 pins and PA9-PA11 pins of the microcontroller U1A. The PB13 pin of the microcontroller U1A is connected to the resistor R19 and connected to the x-axis control end of the 3-axis stepper motor. The PB14 pin of the microcontroller U1A is connected to the resistor R20 and connected to the y-axis control end of the 3-axis stepper motor. The PB15 pin of the microcontroller U1A is connected to the resistor R22 and connected to the z-axis control end of the 3-axis stepper motor.
[0048] For laser control, PB0 of the single-chip microcomputer U1A is connected to resistor R23 and connected to the first control terminal of the matrix laser power supply; PB1 of the single-chip microcomputer U1A is connected to resistor R24 and connected to the second control terminal of the matrix laser power supply; PB4 of the single-chip microcomputer U1A is connected to resistor R25 and connected to the third control terminal of the matrix laser power supply; PB5 of the single-chip microcomputer U1A is connected to resistor R26 and connected to the fourth control terminal of the matrix laser power supply; PB6 of the single-chip microcomputer U1A is connected to resistor R27 and connected to the fifth control terminal of the matrix laser power supply; PB7 of the single-chip microcomputer U1A is connected to resistor R29 and connected to the sixth control terminal of the matrix laser power supply; PB8 of the single-chip microcomputer U1A is connected to resistor R30 and connected to the seventh control terminal of the matrix laser power supply; PB9 of the single-chip microcomputer U1A is connected to resistor R31 and connected to the eighth control terminal of the matrix laser power supply; PB10 of the single-chip microcomputer U1A is connected to resistor R33 and connected to the ninth control terminal of the matrix laser power supply.
[0049] As shown in Figure 2-4, the specific circuit structure and principles include: crystal oscillator Y1 is connected in series between pins 8 and 9 of the microcontroller U1B, crystal oscillator Y2 is connected in series between pins 23 and 24 of the microcontroller U1D, pins 8 and 9 are grounded via capacitors C4 and C5 respectively, reset pin 25 of the microcontroller U1 is connected to ground and power supply voltage via capacitor C8 and resistor R2 respectively, and pin 32 of the chip UIF is connected to the power supply voltage via resistor L1 and grounded via C9.
[0050] The buzzer module is connected to the BEEP module by connecting the PB8 pin of the microcontroller U1A. The PB8 pin of the microcontroller U1A is connected to the b pin of the transistor Q1 through the resistor R18. The c pin of the transistor Q1 is connected to the power supply voltage through the buzzer BZ1, and the e pin of the transistor Q1 is grounded.
[0051] The power module is an AMS1117-3.3 chip. Its IN (input) pin 3 is connected to the voltage 5V, its OUT (output) pin 2 is connected to its voltage 3V3, and its pin 1 is connected to GND (ground). The CPU power supply comes from ASM1117, which converts 5V into 3V.
[0052] The matrix keyboard module is a 4*4 Key module connected to PA0-PA7 of the microcontroller U1A. The matrix function 4*4 is realized by staggered connection of the PA0-PA7 pins; the PA0 pin of the microcontroller U1A is connected to the resistor R7 and the power supply 3.3V, the PA1 pin is connected to the resistor R8 and the power supply 3.3V, the PA2 pin is connected to the resistor R9 and the power supply 3.3V, the PA4 pin is connected to the resistor R12 and the power supply 3.3V, the PA5 pin is connected to the resistor R13 and the power supply 3.3V, the PA6 pin is connected to the resistor R15 and the power supply 3.3V, and the PA4 pin is connected to the resistor R17 and the power supply 3.3V.
[0053] The stepper motor control module uses the PB13-15 pins and PA9-PA11 pins of the microcontroller U1A to complement each other to achieve dead zone control. The PB13 pin of the microcontroller U1A is connected to the resistor R19 and connected to the motor control 1 (x-axis), the PB14 pin of the microcontroller U1A is connected to the resistor R20 and connected to the motor control 2 (y-axis), and the PB15 pin of the microcontroller U1A is connected to the resistor R22 and connected to the motor control 3 (z-axis); the motor control 1 (x-axis) uses the PB13 pin to redefine the function timer T1M1_CH1N, the motor control 2 (y-axis) uses the PB14 pin to redefine the function timer T1M1_CH2N, and the motor control 3 (z-axis) uses the PB15 pin to redefine the function timer T1M1_CH3N. (The PA8-PA10 pins of U1A can also achieve the same function. The motor control 1 (x-axis) uses the PA8 pin to redefine the function timer TIM1 CH1, motor control 2 (y-axis) uses PA9 pin to redefine function as timer TIM1CH2, and motor control 3 (z-axis) uses PA10 pin to redefine function as timer TIM1CH3).
[0054] The PB0-PB1 pins and PB4-PB11 pins of the laser control module microcontroller U1A are connected to the Light Source Control module. The PB0 of the microcontroller U1A is connected to the resistor R23 and connected to the 1 of the Light module, and the PB0 pin is used to redefine the function of the timer TIM3CH3; the PB1 of the microcontroller U1A is connected to the resistor R24 and connected to the 2 of the Light module, and the PB1 pin is used to redefine the function of the timer TIM3CH4; the PB4 of the microcontroller U1A is connected to the resistor R25 and connected to the 3 of the Light module, and the PB4 pin is used to redefine the function of the timer TIM3CH1; the PB5 of the microcontroller U1A is connected to the resistor R26 and connected to the 4 of the Light module, and the PB5 pin is used to redefine the function of the timer TIM3CH2; the PB6 of the microcontroller U1A is connected to the resistor R27 and connected to the 5 of the Light module, and the PB6 pin is used to redefine the function of the timer TIM4CH1; the microcontroller U1A PB7 of the microcontroller U1A is connected to resistor R29 and connected to pin 6 of the Light module, and the PB7 pin is used to redefine the function of timer TIM4CH2; PB8 of the microcontroller U1A is connected to resistor R30 and connected to pin 7 of the Light module, and the PB8 pin is used to redefine the function of timer TIM4CH3; PB9 of the microcontroller U1A is connected to resistor R31 and connected to pin 8 of the Light module, and the PB9 pin is used to redefine the function of timer TIM4CH4; PB10 of the microcontroller U1A is connected to resistor R33 and connected to pin 9 of the Light module, and the PB10 pin is used to redefine the function of timer TIM2CH3; PB11 of the microcontroller U1A is connected, and the PB11 pin is used to redefine the function of timer TIM2CH4. (The laser module in the design adopts a 3*3 matrix structure and only requires 9 PWM control pins).
[0055] Obviously, the specific implementation of the present invention is not limited to the above-mentioned methods. As long as various non-substantial improvements are made using the method concept and technical solution of the present invention, they are all within the scope of protection of the present invention.
Claims
1. A multiple light source control system for photodynamic therapy, characterized in that: It includes a single-chip microcomputer, a matrix laser source, a multi-way switching power supply, a 3-axis stepping motor, and a matrix keyboard. The multi-way switching power supply outputs multiple types of power supply voltages for the single-chip microcomputer, the 3-axis stepping motor, and the matrix laser power supply respectively; the input end of the single-chip microcomputer is connected to the matrix keyboard for outputting adjustment parameters; the output end of the single-chip microcomputer is respectively connected to the 3-axis stepping motor and the matrix laser power supply for controlling the matrix laser power supply and the 3-axis stepping motor.
2. A multiple light source control system for photodynamic therapy as claimed in claim 1, characterized in that: The system also includes an OLED display and a buzzer module. The output end of the single-chip microcomputer is respectively connected to the OLED display and the buzzer module, and is used to control the OLED display to realize the output state of the matrix laser light source. The buzzer is used to send a reminder signal to the light source output.
3. A multiple light source control system for photodynamic therapy according to claim 1 or 2, characterized in that: The single chip microcomputer is a STM32 series single chip microcomputer.
4. A multiple light source control system for photodynamic therapy according to claim 1 or 2, characterized in that: The STM32 series microcontroller includes multiple chip units U1A, U1B, U1C, U1D, and U1E, and its model is STM32 F103ZET6 microcontroller.
5. A multiple light source control system for photodynamic therapy as claimed in claim 4, characterized in that: A crystal oscillator Y1 is connected in series between pins 8 and 9 of microcontroller U1B, a crystal oscillator Y2 is connected in series between pins 23 and 24 of microcontroller U1D, pins 8 and 9 are grounded via capacitors C4 and C5 respectively, reset pin 25 of microcontroller U1 is connected to ground and power supply voltage via capacitor C8 and resistor R2 respectively, pin 32 of chip UIF is connected to power supply voltage via resistor L1 and grounded via C9.
6. A multiple light source control system for photodynamic therapy as claimed in claim 4, characterized in that: The PB8 pin of the microcontroller U1A is connected to the input BEEP pin of the buzzer module. The PB8 pin of the microcontroller U1A is connected to the b pin of the transistor Q1 through the resistor R18. The c pin of the transistor Q1 is connected to the power supply voltage through the buzzer BZ1. The e pin of the transistor Q1 is grounded. The b pole and the e pole of the transistor Q1 are connected.
7. A multiple light source control system for photodynamic therapy as claimed in claim 4, characterized in that: The multi-channel switching power supply is integrated with a voltage stabilizing chip, which is used to convert the input voltage into the 3.3V voltage required by the single-chip microcomputer for power supply.
8. A multiple light source control system for photodynamic therapy as claimed in claim 4, characterized in that: The matrix keyboard module is a 4*4 Key module connected to PA0-PA7 of the microcontroller U1A, and the matrix function 4*4 is realized by staggered connection of PA0-PA7 pins; the PA0 pin of the microcontroller U1A is connected to resistor R7 and connected to the power supply 3.3V, the PA1 pin is connected to resistor R8 and connected to the power supply 3.3V, the PA2 pin is connected to resistor R9 and connected to the power supply 3.3V, the PA4 pin is connected to resistor R12 and connected to the power supply 3.3V, the PA5 pin is connected to resistor R13 and connected to the power supply 3.3V, the PA6 pin is connected to resistor R15 and connected to the power supply 3.3V, and the PA4 pin is connected to resistor R17 and connected to the power supply 3.3V.
9. A multiple light source control system for photodynamic therapy as claimed in claim 4, characterized in that: The stepper motor control is achieved by complementary dead zone control of the PB13-15 pins and PA9-PA11 pins of the single-chip microcomputer U1A. The PB13 pin of the single-chip microcomputer U1A is connected to the resistor R19 and connected to the x-axis control end of the 3-axis stepper motor. The PB14 pin of the single-chip microcomputer U1A is connected to the resistor R20 and connected to the y-axis control end of the 3-axis stepper motor. The PB15 pin of the single-chip microcomputer U1A is connected to the resistor R22 and connected to the z-axis control end of the 3-axis stepper motor.
10. A multiple light source control system for photodynamic therapy according to claim 4, characterized in that: The laser control is that PB0 of the single-chip computer U1A is connected to the resistor R23 and connected to the first control terminal of the matrix laser power supply; PB1 of the single-chip computer U1A is connected to the resistor R24 and connected to the second control terminal of the matrix laser power supply; PB4 of the single-chip computer U1A is connected to the resistor R25 and connected to the third control terminal of the matrix laser power supply; PB5 of the single-chip computer U1A is connected to the resistor R26 and connected to the fourth control terminal of the matrix laser power supply; PB6 of the single-chip computer U1A is connected to the resistor R27 and connected to the fifth control terminal of the matrix laser power supply; PB7 of the single-chip computer U1A is connected to the resistor R29 and connected to the sixth control terminal of the matrix laser power supply; PB8 of the single-chip computer U1A is connected to the resistor R30 and connected to the seventh control terminal of the matrix laser power supply; PB9 of the single-chip computer U1A is connected to the resistor R31 and connected to the eighth control terminal of the matrix laser power supply; PB10 of the single-chip computer U1A is connected to the resistor R33 and connected to the ninth control terminal of the matrix laser power supply.
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