An aerosol generation consumable

By integrating somatosensory compounds into aerosol generation devices and oral pouches, the patent enhances user experience through non-nicotine somatosensory effects, providing a more nuanced sensory experience beyond traditional flavor and smell.

WO2025153704A1PCT designated stage expired Publication Date: 2025-07-24JT INTERNATIONAL SA
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Patent Information

Application Number
PCT/EP2025/051191
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-01-19
Filing Date
2025-01-17
Publication Date
2025-07-24

AI Technical Summary

Technical Problem

Existing aerosol generation devices and nicotine oral delivery products often overpower users with flavor and smell additives, lacking a desirable sensory experience beyond flavor and smell.

Method used

Incorporating somatosensory compounds like alkyl isothiocyanate and unsaturated aldehydes into aerosol generation consumables and oral pouches to provide a higher somatosensory effect without nicotine, thereby enhancing the user experience.

Benefits of technology

The somatosensory compounds deliver a more pronounced sensory experience, such as warming, cooling, or numbing, without overwhelming flavor or smell, addressing the limitations of traditional additives.

✦ Generated by Eureka AI based on patent content.

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Abstract

An aerosol generation consumable for use with an aerosol generation device, the consumable comprising a composition, wherein the composition comprises: aerosol precursor material; and one or more somatosensory compounds, wherein the or each of the somatosensory compounds have a higher somatosensory effect than the flavour and / or smell effect thereof and wherein the or each of the somatosensory compounds is not nicotine.
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Description

[0001] An Aerosol Generation Consumable

[0002] The present disclosure relates to a composition comprising one or more somatosensory compounds and an aerosol generation consumable comprising such a composition. The present disclosure further relates to a device comprising such a consumable and the use of such somatosensory compounds.

[0003] Background

[0004] Aerosol generation devices (or electronic cigarettes or "e-cigarettes") have been developed as an alternative to traditional cigarettes as a means for volatilizing active components for inhalation without combustion, while at the same time providing the user with an oral experience similar to that of traditional cigarette smoking.

[0005] Such aerosol generation devices typically comprise consumables which comprise compositions that can be volatilized and inhaled as a vapour by a user (such as an adult vaper). There are further products, such as nicotine oral delivery products, which provide different ways of administering nicotine to a user. Nicotine oral delivery products typically take the form of a nicotine composition enclosed within a pouch.

[0006] It is common for both types of compositions to comprise a flavour additive with the aim of providing an enhanced user satisfaction. Flavour additives may be added to provide a flavour and / or smell effect to the user. However, for some users, vapour containing flavour additives is overpowering and undesirable.

[0007] The overall sensory experience of inhaling vapour is more than just the flavour provided to the user. It may be preferable to provide a different effect to the user, other than flavour and / or smell.

[0008] There is a need to provide aerosol generation consumables that can provide a desirable sensory effect experience, i.e., for example by providing an improved throat sensation.

[0009] It is one aim of the present invention, amongst others, to provide an aerosol generation consumable that addresses at least one disadvantage of the prior art, whether identified here or elsewhere, or to provide an alternative to existing aerosol generation consumables. Summary of the Invention

[0010] According to aspects of the present invention, there are provided an aerosol generation consumable, an aerosol generating device, the use of a somatosensory compound, and an oral pouch comprising one or more somatosensory compounds.

[0011] According to a first aspect of the present invention, there is provided an aerosol generation consumable for use with an aerosol generation device, the consumable comprising a composition, wherein the composition comprises: aerosol precursor material; and one or more somatosensory compounds, wherein the or each of the somatosensory compounds have a higher somatosensory effect than the flavour and / or smell effect thereof and wherein the or each of the somatosensory compounds is not nicotine.

[0012] According to a second aspect of the present invention, there is provided an aerosol generation device comprising the aerosol generation consumable according to the first aspect.

[0013] According to a third aspect of the present invention, there is provided use of a somatosensory compound for providing a higher somatosensory effect than the flavour and / or smell effect thereof in an aerosol generation consumable or in an oral pouch, wherein the somatosensory compound is not nicotine.

[0014] According to a fourth aspect of the present invention, there is provided an oral pouch comprising one or more somatosensory compounds, wherein the or each of the somatosensory compounds has a higher somatosensory effect than the flavour and / or smell effect thereof and wherein the or each of the somatosensory compounds is not nicotine.

[0015] Other features of the invention will be apparent from the dependent claims, and from the description which follows.

[0016] Features described in relation to the second, third and fourth aspects may have any of the suitable features and advantages described in relation to the first aspect. Detailed Description of the Invention

[0017] Unless otherwise stated, the following terms used in the specification and claims have the meanings set out below.

[0018] As used herein, the term “aerosol precursor material”, “vapour precursor material” or “vaporizable material” are used synonymously and may refer to a material and / or composition, which may for example comprise nicotine or tobacco and a vaporising agent. The aerosol precursor material is configured to release an aerosol when heated or otherwise mechanically stimulated (such as by vibrations). Tobacco may take the form of various materials such as shredded tobacco, granulated tobacco, tobacco leaf and / or reconstituted tobacco. Typically, tobacco may comprise a small amount of vaporising agent, such as glycerol. Nicotine may be in the form of nicotine salts. Suitable vaporising agents include: a polyol such as sorbitol, glycerol, and glycols like propylene glycol or triethylene glycol; a non-polyol such as monohydric alcohols, acids such as lactic acid, glycerol derivatives, esters such as triacetin, triethylene glycol diacetate, triethyl citrate, glycerin or vegetable glycerin. Preferably, the vaporising agent comprises glycerol and / or glycol. In some examples, the aerosol precursor material is substantially a liquid or a gel that holds or comprises one or more solid particles, such as tobacco particles extracted from tobacco materials or suspended in a solution or gel.

[0019] The aerosol precursor material may comprise cellulose-based sheet material or paper, and a vaporising agent.

[0020] An aerosol generation device is configured to aerosolise an aerosol precursor material without combustion in order to facilitate delivery of an aerosol to a user. Furthermore, and as is common in the technical field, the terms “vapour” and “aerosol”, and related terms such as “vaporize”, “volatilize” and “aerosolise”, may generally be used interchangeably.

[0021] As used herein, the term “aerosol generation device” is synonymous with “aerosol generating device” or “device” and may include a device configured to heat an aerosol precursor material and deliver an aerosol to a user, typically without combusting the aerosol precursor material. The device may be portable. “Portable” may refer to the device being for use when held by a user. The device may be adapted to generate a variable amount of aerosol, which can be controlled by a user input.

[0022] As used herein, the term “aerosol” may include a suspension of vaporizable material as one or more of: solid particles; liquid droplets; gas. Said suspension may be in a gas including air. Aerosol herein may generally refer to / include a vapour. Aerosol may include one or more components of the vaporizable material.

[0023] As used herein, the term “somatosensory compound(s)” may refer to compounds which provide a somatosensory effect to the user. As used herein, the term “somatosensory effect” refers to effects such as warming, cooling, fizzing, numbing, pungency, astringency, pain, itching, touch, and pressure and / or kokumi. The term “somatosensory effect” does not include flavour and / or smell.

[0024] The composition comprises aerosol precursor material and one or more somatosensory compounds. The one or more somatosensory compounds may be an isocyanate or an aldehyde somatosensory compound, or a mixture thereof. The one or more somatosensory compounds may be selected from alkyl isothiocyanate and / or linear or branched unsaturated aldehyde compounds. Preferably, the one or more somatosensory compounds may be selected from alkyl isothiocyanate and / or linear or branched unsaturated aldehyde compounds.

[0025] Suitably, the one or more somatosensory compounds are selected from amyl isothiocyanate, isoamyl isothiocyanate, ethyl isothiocyanate, 2-ethyl-2-hexenal, 2,4- hexadienal or mixtures thereof.

[0026] The somatosensory compounds may be chemically synthesized or natural extracts from foods, preferably the somatosensory compounds may be chemically synthesized.

[0027] The composition may not comprise a flavour additive. As used herein, a flavour additive refers to a compound which is added with the aim of providing a flavour and / or smell to the user. The flavour additive may provide a higher flavour and / or smell effect than the somatosensory effect thereof. Preferably, the composition does not comprise a flavour additive that has a higher flavour and / or smell effect than the somatosensory effect thereof. Suitably, the flavour additive may have a higher flavour and / or smell value than the somatosensory effect value thereof, as measured on the labelled magnitude scale (LMS), discussed in detail below. Preferably, the composition does not comprise a flavour additive that has a higher flavour and / or smell value than the somatosensory effect thereof, as measured on the labelled magnitude scale (LMS). By “higher flavour and / or smell effect than the somatosensory effect thereof” is meant that the flavour and / or smell effect provided by the compounds to the user is stronger than the somatosensory effect of said compounds. For example, the ratio of the flavour and / or smell labelled magnitude scale value to the somatosensory labelled magnitude scale value of the flavour additive may be greater than 1 :1 , such as 1.5:1 , such as 2: 1 , such as 3:1 , such as 4:1 , such as 5:1 , such as 6:1 , such as 7:1 such as 8:1 , such as 9:1 , such as 10:1 , such as 11 :1 , or even 12:1 The presence of such a flavour additive may disturb the somatosensory effect of the somatosensory compound on the user.

[0028] A flavour additive may be selected from one or more of cinnamon, chamomile, kudzu (pueraria lobata), amacha (hydrangeae dulcis folium), lavender, cardamom, caryophyllus, nutmeg, bergamot, geranium, honey essence, rose oil, cassia bark, caraway, jasmine, ginger, coriander, vanilla extract, spearmint, peppermint, cassia, coffee, celery, cascarilla, sandalwood, ylang ylang, fennel, anise, licorice, St John's bread, prune extract, peach extract, glucose, fructose, isomerized saccharide, caramel, cocoa powder, cocoa extract, isoamyl acetate, linalyl acetate, isoamyl propionate, linalyl butyrate, ionone, damascenone, ethyl maltol, geraniol, linalool, anethole, vanillin, benzaldehyde, anisaldehyde, y-undecalactone, y-nonalactone, musk, ambergris, civet, castoreum, imonene and pinene, or any extract thereof.

[0029] Suitably, the composition may not comprise any of cinnamon, chamomile, kudzu (pueraria lobata), amacha (hydrangeae dulcis folium), lavender, cardamom, caryophyllus, nutmeg, bergamot, geranium, honey essence, rose oil, cassia bark, caraway, jasmine, ginger, coriander, vanilla extract, spearmint, peppermint, cassia, coffee, celery, cascarilla, sandalwood, ylang ylang, fennel, anise, licorice, St John's bread, prune extract, peach extract, glucose, fructose, isomerized saccharide, caramel, cocoa powder, cocoa extract, isoamyl acetate, linalyl acetate, isoamyl propionate, linalyl butyrate, ionone, damascenone, ethyl maltol, geraniol, linalool, anethole, vanillin, benzaldehyde, anisaldehyde, y-undecalactone, y-nonalactone, musk, ambergris, civet, castoreum, limonene and pinene, or any extract thereof.

[0030] Suitably, the composition may not comprise a flavour additive selected from cinnamon, ginger, vanillin, limonene and linalool, or any extract thereof. Preferably, the composition may not comprise a flavour additive selected from cinnamon, ginger and vanillin, or any extract thereof, such as cinnamaldehyde or gingerol. For example, the composition may not comprise cinnamon (cinnamaldehyde).

[0031] The or each of the somatosensory compounds have a higher somatosensory effect than the flavour and / or smell effect thereof. Suitably, the or each of the somatosensory compounds have a higher somatosensory effect than the flavour and smell effect thereof. Advantageously, the somatosensory compounds provide an effect to the user without providing any flavour and / or smell to the user. Suitably, the or each of the one or more somatosensory compounds have a higher somatosensory labelled magnitude scale (LMS) value than the flavour and / or smell labelled magnitude scale value thereof.

[0032] The labelled magnitude scale is used for determining subjective flavour and / or smell, and somatosensory effects of compounds, in which a trained sensory panel tests compounds and provides a value on the defined scale according to the amount of flavour and / or smell and / or somatosensory effect experienced.

[0033] The ratio of the somatosensory labelled magnitude scale value to the flavour and / or smell labelled magnitude scale value of the or each somatosensory compound may be greater than 2:1 , such as 4:1 , such as 6:1 , such as 8:1 , such as 10:1 , such as 12:1 , such as 14:1 , or even 16:1.

[0034] Suitably, the somatosensory compound is not tobacco or a component thereof.

[0035] The composition may further comprise tobacco. Suitably, the tobacco is substantially free of 2,4-hexadienal, or suitably essentially free of 2,4-hexadienal, or suitably completely free of 2,4-hexadienal. By “substantially free” we mean to refer to aqueous coating compositions containing less than 1000 parts per million (ppm) of any of the compounds or derivatives thereof mentioned above. By “essentially free” we mean to refer to aqueous coating compositions containing less than 100 ppm of any of the compounds or derivatives thereof mentioned above. By “completely free” we mean to refer to aqueous coating compositions containing less than 20 parts per billion (ppb) of any of the compounds or derivatives thereof.

[0036] The composition may further comprise tobacco which has been treated to reduce its flavour, and / or smell. Suitably, the tobacco is treated by heating and / or washing with solvent. Such methods of treating the tobacco would be known to those skilled in the art. The tobacco may be present in the aerosol precursor material.

[0037] Suitably, the tobacco may be treated by heating the tobacco to within any suitable temperature range. For example, the tobacco may be heated to a temperature from 150 to 400°C. The tobacco may be heated from 160 to 230°C. The tobacco may be heated for any suitable time to reduce the flavour and / or smell. The tobacco may be heated for 20 seconds to 120 minutes. For example, the tobacco may be heated for 2 minutes to 100 minutes, such as for 10 minutes to 90 minutes, such as for 10 minutes to 10 minutes, such as 10 minutes to 70 minutes, or even for 10 minutes to 30 minutes. The tobacco may be heated to between 150 to 400°C for 20 seconds to 120 minutes.

[0038] The solvent may be selected from any known suitable solvent that will wash tobacco to reduce its flavour and / or smell. The solvent may be selected from an aqueous solvent, an organic solvent, inorganic solvent, or a mixture of an aqueous and an organic solvent. The solvent may be selected from water, ethanol, hydrochloric acid, malic acid, acetic acid, potassium carbonate, sodium carbonate, sodium bicarbonate, sodium carbonate peroxide, sodium hypochlorite, sodium hydroxide, potassium hydroxide, calcium hydroxide, sodium formate, or potassium formate. Preferably, the tobacco is washed with one solvent and then washed again with a further solvent (i.e. washed with two or more solvents).

[0039] The composition may further comprise cellulose-based material or natural solid material, such as other plant (non-tobacco plant) -based or botanical material. The cellulose- based material or natural solid material may be present in the aerosol precursor material.

[0040] The composition may further comprise nicotine. The nicotine may be in any suitable form. The nicotine may be extracted from tobacco or may be synthetic nicotine. The nicotine may be in the form of a nicotine salt or stabilized nicotine. The nicotine may be present as part of the aerosol precursor material. The composition may comprise aerosol precursor material; one or somatosensory compounds; and nicotine.

[0041] Suitably, the consumable may comprise a liquid aerosol precursor material.

[0042] Suitably, the consumable may comprise a solid aerosol precursor material. Suitably, the consumable may be a heat not burn stick. The heat not burn stick may comprise a solid aerosol precursor material, filter, wrapping paper and tipping paper. The composition comprising the one or more somatosensory compounds may be present in any of the solid aerosol precursor material, filter, wrapping paper and tipping paper. Suitably, the solid aerosol precursor material may be tobacco.

[0043] The content of the aerosol precursor material in the composition is not particularly limited and depends on the device for which the consumable is for use with and an amount to sufficiently generate aerosol.

[0044] For example, when the consumable comprises a liquid aerosol precursor material, the amount of aerosol precursor material present in the composition may be at least 70 wt.% of the total composition, such as at least 85 wt.%, such as at least 90 wt.%, or even 99 wt.% of the total composition. Typically, when the consumable comprises a liquid aerosol precursor material, the amount of the one or more somatosensory compounds present in the composition may be from 1 to 15 wt.% of the total composition, such as from 2 to 12 wt.%, such as from 4 to 10 wt.% of the total composition, or even 5 to 10 wt.% of the total composition. The amount of the one or more somatosensory compounds present in the composition may be at least 1 wt.% of the total composition, such as at least 2 wt.%, such as at least 4 wt.%, or even 5 wt.% of the total composition.

[0045] The one or more somatosensory compounds may be selected from amyl isothiocyanate, isoamyl isothiocyanate, ethyl isothiocyanate, 2-ethyl-2-hexenal, 2,4- hexadienal or mixtures thereof and the consumable may comprise a liquid aerosol precursor material, and the amount of the one or more somatosensory compounds present in the composition may be from 1 to 15 wt.%, such as from 2 to 12 wt.%, such as from 4 to 10 wt.% of the total composition, or even 5 to 10 wt.% of the total composition.

[0046] The amount of nicotine present in the composition may be from 1 to 15 wt.% of the total composition, such as from 2 to 12 wt.%, such as from 4 to 10 wt.% of the total composition, or even 5 to 10 wt.% of the total composition. The amount of nicotine present in the composition may be at least 1 wt.% of the total composition, such as at least 2 wt.%, such as at least 4 wt.%, or even 5 wt.% of the total composition. For example, when the consumable comprises a solid aerosol precursor material, the amount of aerosol precursor material present in the composition may be at least 5 wt.% of the total composition, such as at least 7 wt.%, such as at least 10 wt.%, or even 15 wt.% of the total composition. The amount of aerosol precursor material present in the composition may be up to 50 wt.% of the total composition, such as up to 40 wt.%, such as up to 30 wt.%, or even up to 20 wt.% of the total composition.

[0047] In this example, the amount of the one or more somatosensory compounds present in the composition is any amount sufficient to provide an effect to the user. Typically, when the consumable comprises a solid aerosol precursor material, the amount of the one or more somatosensory compounds present in the composition is at least 10,000 parts per million (ppm), more typically at least 20,000 ppm, such as at least 25,000 ppm. Typically, the amount of the one or more somatosensory compounds present in the composition is up to 50,000 ppm, more typically up to 40,000 ppm, such as up to 33,000 ppm.

[0048] When the consumable comprises a solid aerosol precursor material, the amount of the one or more somatosensory compounds present in the composition may be from 10,000 parts per million (ppm) to 50,000 ppm. Typically, the amount of the one or more somatosensory compounds present in the composition may be from 20,000 parts per million (ppm) to 40,000 ppm, such as 25,000 parts per million (ppm) to 33,000 ppm.

[0049] The one or more somatosensory compounds may be selected from amyl isothiocyanate, isoamyl isothiocyanate, ethyl isothiocyanate, 2-ethyl-2-hexenal, 2,4- hexadienal or mixtures thereof and the consumable may comprise a solid aerosol precursor material, and the amount of the one or more somatosensory compounds present in the composition may be from 10,000 parts per million (ppm) to 50,000 ppm. Typically, the amount of the one or more somatosensory compounds present in the composition may be from 20,000 parts per million (ppm) to 40,000 ppm, such as 25,000 parts per million (ppm) to 33,000 ppm.

[0050] A second aspect of the present invention provides an aerosol generation device comprising the aerosol generation consumable according to the first aspect.

[0051] The aerosol generation device according to the second aspect of the present invention can be any type of aerosol generation device known to a person skilled in the art. In general, the term “aerosol generation device”, “electronic cigarette”, “e-cigarette” or “low temperature vaporization device”, refers to an electronic inhaler that vaporizes a liquid composition or solution into an aerosol mist, simulating the act of tobacco smoking.

[0052] When the aerosol generation device is for heating a consumable comprising a liquid aerosol precursor material, the device comprises a coil and wick. When the aerosol generation device is for heating a consumable comprising a solid aerosol precursor material, the device comprises a heater.

[0053] A third aspect of the present invention provides the use of a somatosensory compound for providing a higher somatosensory effect than the flavour and / or smell effect thereof in an aerosol generation consumable or in an oral pouch, wherein the somatosensory compound is not nicotine.

[0054] In the third aspect, the somatosensory compound may be selected from alkyl isothiocyanate and / or linear or branched unsaturated aldehyde compounds, or mixtures thereof. Preferably, the one or more somatosensory compounds may be selected from alkyl isothiocyanate and / or linear or branched unsaturated aldehyde compounds, or mixtures thereof.

[0055] Suitably, the somatosensory compounds may be selected from amyl isothiocyanate, isoamyl isothiocyanate, ethyl isothiocyanate, 2-ethyl-2-hexenal, 2,4-hexadienal or mixtures thereof.

[0056] There is also provided a method for using a somatosensory compound to provide a higher somatosensory effect than the flavour and / or smell effect thereof in an aerosol generation consumable or in an oral pouch, wherein the somatosensory compound is not nicotine.

[0057] A fourth aspect of the present invention provides an oral pouch comprising one or more somatosensory compounds, wherein the or each of the somatosensory compounds has a higher somatosensory effect than the flavour and / or smell effect thereof and wherein the or each of the somatosensory compounds is not nicotine. Typically, the oral pouch comprises a composition. The one or more somatosensory compounds may be present in the composition. In other words, the oral pouch comprises a composition (oral pouch composition) comprising one or more somatosensory compounds. The somatosensory compounds may be selected from alkyl isothiocyanate and / or linear or branched unsaturated aldehyde compounds. Preferably, the one or more somatosensory compounds may be selected from alkyl isothiocyanate and / or linear or branched unsaturated aldehyde compounds, or mixtures thereof.

[0058] Suitably, the one or more somatosensory compounds are selected from amyl isothiocyanate, isoamyl isothiocyanate, ethyl isothiocyanate, 2-ethyl-2-hexenal, 2,4- hexadienal or mixtures thereof.

[0059] The oral pouch may comprise nicotine in any suitable form. For example, nicotine may be contained as a compound; a nicotine-containing compound, such as nicotine salt or stabilized nicotine (e.g., nicotine adsorbed on ion-exchange resin); a nicotine source, such as tobacco leaves; or a nicotine-containing extract obtained by extracting nicotine from a nicotine-containing substance, such as tobacco leaves.

[0060] When present, the nicotine content present in the oral pouch composition is not limited, but is typically at least 0.1 wt.% of the total composition, such as at least 1 wt.%, and typically up to 10 wt.%, such as up to 7 wt.%. The nicotine content present in the oral pouch composition may be from 0.1 to 10 wt.%, such as from 1 to 9 wt.%, such as from 2 to 8 wt.%, or even from 3 to 7 wt.%.

[0061] The somatosensory compound content in the oral pouch composition is typically at least 0.08 wt.% of the total composition, more typically at least 1 wt.%, such as at least 2 wt.%. The somatosensory compound content in the oral pouch is typically up to 5 wt.%, more typically up to 4 wt.%, such as up to 3 wt.%. The somatosensory compound content in the oral pouch composition may be from 0.08 to 5 wt.%, such as from 1 to 4 wt.%, such as from 2 to 3 wt.%.

[0062] The one or more somatosensory compounds may be selected from amyl isothiocyanate, isoamyl isothiocyanate, ethyl isothiocyanate, 2-ethyl-2-hexenal, 2,4- hexadienal or mixtures thereof, and the somatosensory compound content in the oral pouch composition is typically at least 0.08 wt.% of the total composition, more typically at least 1 wt.%, such as at least 2 wt.%. The somatosensory compound content in the oral pouch is typically up to 5 wt.%, more typically up to 4 wt.%, such as up to 3 wt.%. The somatosensory compound content in the oral pouch composition may be from 0.08 to 5 wt.%, such as from 1 to 4 wt.%, such as from 2 to 3 wt.%.

[0063] The oral pouch may comprise further additives. Examples of the further additives include one or more of water, a pH adjuster, a sweetener, a humectant, a whitening agent, a base material, a gelling agent, and an emulsifier.

[0064] The gelling agent may be selected from pectin, carrageenan, gum arabic, xanthan gum, gellan gum, and gum tragacanth. The base material may be selected from cellulose and silica. The pH adjuster may be selected from sodium carbonate, sodium hydrogen carbonate, potassium carbonate, potassium bicarbonate, potassium phosphate, anhydrous sodium phosphate, sodium dihydrogen phosphate, and sodium citrate. The humectant may be selected from glycerin and propylene glycol. When present, the gelling agent content, base material content, pH adjuster content, and humectant content in the oral pouch composition is not limited and each component may be present in any suitable amount as understood by the skilled person.

[0065] The oral pouch may not comprise a flavour additive.

[0066] The oral pouch may not comprise a flavour additive selected from one or more of cinnamon, chamomile, kudzu (pueraria lobata), amacha (hydrangeae dulcis folium), lavender, cardamom, caryophyllus, nutmeg, bergamot, geranium, honey essence, rose oil, cassia bark, caraway, jasmine, ginger, coriander, vanilla extract, spearmint, peppermint, cassia, coffee, celery, cascarilla, sandalwood, ylang ylang, fennel, anise, licorice, St John's bread, prune extract, peach extract, glucose, fructose, isomerized saccharide, caramel, cocoa powder, cocoa extract, isoamyl acetate, linalyl acetate, isoamyl propionate, linalyl butyrate, ionone, damascenone, ethyl maltol, geraniol, linalool, anethole, vanillin, benzaldehyde, anisaldehyde, y-undecalactone, y- nonalactone, musk, ambergris, civet, castoreum, limonene and pinene, or any extract thereof.

[0067] Suitably, the composition may not comprise any of cinnamon, chamomile, kudzu (pueraria lobata), amacha (hydrangeae dulcis folium), lavender, cardamom, caryophyllus, nutmeg, bergamot, geranium, honey essence, rose oil, cassia bark, caraway, jasmine, ginger, coriander, vanilla extract, spearmint, peppermint, cassia, coffee, celery, cascarilla, sandalwood, ylang ylang, fennel, anise, licorice, St John's bread, prune extract, peach extract, glucose, fructose, isomerized saccharide, caramel, cocoa powder, cocoa extract, isoamyl acetate, linalyl acetate, isoamyl propionate, linalyl butyrate, ionone, damascenone, ethyl maltol, geraniol, linalool, anethole, vanillin, benzaldehyde, anisaldehyde, y-undecalactone, y-nonalactone, musk, ambergris, civet, castoreum, limonene and pinene, or any extract thereof.

[0068] Suitably, the composition may not comprise a flavour additive selected from cinnamon, ginger, vanillin, limonene and linalool, or any extract thereof. Preferably, the composition may not comprise a flavour additive selected from cinnamon, ginger and vanillin, or any extract thereof, such as cinnamaldehyde or gingerol. For example, the composition may not comprise cinnamon (cinnamaldehyde).

[0069] Definitions

[0070] The term "alkyl" as used herein, refers to saturated, straight- or branched-chain hydrocarbon radicals derived by removal of a single hydrogen atom from an aliphatic moiety. An alkyl group is preferably a “C1-20 alkyl group”, that is an alkyl group that is a straight or branched chain with 1 to 20 carbons. The alkyl group therefore has 1 , 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 , 12, 13, 14, 15, 16, 17, 18, 19 or 20 carbon atoms. Preferably, an alkyl group is a C1-15 alkyl, preferably a C1-12 alkyl, more preferably a C1-10 alkyl, even more preferably a C1-8 alkyl, even more preferably a C1-6 alkyl group. Specifically, examples of “C1-20 alkyl group" include methyl group, ethyl group, n-propyl group, isopropyl group, n-butyl group, iso-butyl group, sec-butyl group, tert-butyl group, secpentyl, iso-pentyl, n-pentyl group, neopentyl, n-hexyl group, sec-hexyl, n-heptyl group, n-octyl group, n-nonyl group, n-decyl group, n-undecyl group, n-dodecyl group, n- tridecyl group, n-tetradecyl group, n-pentadecyl group, n-hexadecyl group, n- heptadecyl group, n-octadecyl group, n-nonadecyl group, n-eicosyl group, 1 ,1- dimethylpropyl group, 1 ,2-dimethylpropyl group, 2,2-dimethylpropyl group, 1- ethylpropyl group, n-hexyl group, 1-ethyl-2-methylpropyl group, 1 , 1 ,2-trimethylpropyl group, 1 -ethylbutyl group, 1 -methylbutyl group, 2-methylbutyl group, 1 ,1 -dimethylbutyl group, 1 ,2-dimethylbutyl group, 2,2-dimethylbutyl group, 1 ,3-dimethylbutyl group, 2,3- dimethylbutyl group, 2-ethylbutyl group, 2-methylpentyl group, 3-methylpentyl group and the like. The term “linear” as used herein refers to a saturated or unsaturated straight chain, which does not contain any branched or cyclic groups. The term “cyclic group” refers to both aromatic and non-aromatic ring systems.

[0071] The term “unsaturated” means a moiety that has one or more double and / or triple bonds.

[0072] Throughout this specification, the term “comprising” or “comprises” means including the component(s) specified but not to the exclusion of the presence of other components. The term “consisting essentially of” or “consists essentially of” means including the components specified but excluding other components except for materials present as impurities, unavoidable materials present as a result of processes used to provide the components, and components added for a purpose other than achieving the technical effect of the invention. Typically, when referring to compositions, a composition consisting essentially of a set of components will comprise less than 5% by weight, typically less than 3% by weight, more typically less than 1% by weight of non-specified components.

[0073] For the avoidance of doubt, wherein amounts of components in a composition are described in wt%, this means the weight percentage of the specified component in relation to the whole composition referred to. For example, “wherein the total amount of the one or more somatosensory compounds present in the composition may be from 1 to 15 wt.% of the total composition” means that 1 wt% to 15 wt% of the total composition is provided by the one or more somatosensory compounds.

[0074] Examples

[0075] Assessment of the somatosensory experience of compounds

[0076] A standard method for the assessment of somatosensory effect, flavours and smells was used to assess the sensorial experience of liquid compositions in an objective manner.

[0077] Through this method, the sensory characteristics of all products would be determined by a trained sensory panel. The assessors included in the panel would be selected based on their sensory acuity and descriptive ability. Example 1

[0078] Description of the methodology

[0079] A 20 mg undiluted solution of a somatosensory compound was added to an inhaler. For testing the somatosensory compound ethyl isothiocyanate, 20 mg of a propylene glycol solution comprising 1 wt% of ethyl isothiocyanate was used.

[0080] The solution was added to the inside wall of the inhaler, and both ends of the inhaler were closed by non-woven fabric filters. The solution was heated at 60°C within the inhaler and inhaled by the panel as a vapour.

[0081] A Labelled Magnitude Scale (LMS) was used to determine the strength of the sensorial effect on the panel.

[0082] The trained sensory evaluation panel was asked to mark the intensity of sensation (somatosensation / flavour and / or smell) of each sample.

[0083] Sensory evaluation result:

[0084] A list of the somatosensory compounds and comparative compounds tested is set out in Table 1 below, along with the results of the test.

[0085] Example 2

[0086] A 4 mg sample of 2-ethyl-2-hexenal was added to 250 mg of shredded tobacco (Burley 100%, no perfume added after shredding). The shredded tobacco was added into a plastic tube and both ends were closed by non-woven fabric filters. The tube was then heated to 60 °C and the resulting vapour was inhaled by the panel.

[0087] A plastic tube filled with 250 mg of shredded tobacco (Burley 100%, no perfume added after shredding) was also heated to 60 °C and the resulting vapour was inhaled by the panel.

[0088] Sensory evaluation result:

[0089] In the sample comprising 2-ethyl-2-hexenal, the panel perceived a somatosensation change compared to the sample comprising shredded tobacco without 2-ethyl-2- hexanal. The panel did not perceive a change in the flavour / smell of the vapour inhaled from the sample comprising 2-ethyl-2-hexenal, compared to the vapour sample without 2-ethyl-2-hexanal.

[0090] The optional features set out herein may be used either individually or in combination with each other where appropriate and particularly in the combinations as set out in the accompanying claims. The optional features for each aspect or exemplary embodiment of the invention as set out herein are also to be read as applicable to any other aspect or exemplary embodiments of the invention, where appropriate. In other words, the skilled person reading this specification should consider the optional features for each exemplary embodiment of the invention as interchangeable and combinable between different exemplary embodiments. Attention is directed to all papers and documents which are filed concurrently with or previous to this specification in connection with this application and which are open to public inspection with this specification, and the contents of all such papers and documents are incorporated herein by reference.

[0091] All of the features disclosed in this specification (including any accompanying claims, and drawings), and / or all of the steps of any method or process so disclosed, may be combined in any combination, except combinations where at least some of such features and / or steps are mutually exclusive.

[0092] Each feature disclosed in this specification (including any accompanying claims, and drawings) may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise. Thus, unless expressly stated otherwise, each feature disclosed is one example only of a generic series of equivalent or similar features.

[0093] The invention is not restricted to the details of the foregoing embodiment(s). The invention extends to any novel one, or any novel combination, of the features disclosed in this specification (including any accompanying claims, and drawings), or to any novel one, or any novel combination, of the steps of any method or process so disclosed.

Claims

CLAIMS1 . An aerosol generation consumable for use with an aerosol generation device, the consumable comprising a composition, wherein the composition comprises: aerosol precursor material; and one or more somatosensory compounds, wherein the or each of the somatosensory compounds have a higher somatosensory effect than the flavour and / or smell effect thereof and wherein the or each of the somatosensory compounds is not nicotine.

2. The aerosol generation consumable according to claim 1 , wherein the one or more somatosensory compounds are selected from alkyl isothiocyanate and / or linear or branched unsaturated aldehyde compounds, or mixtures thereof.

3. The aerosol generation consumable according to claim 1 or 2, wherein the one or more somatosensory compounds are selected from amyl isothiocyanate, isoamyl isothiocyanate, ethyl isothiocyanate, 2-ethyl-2-hexenal, 2,4- hexadienal or mixtures thereof.

4. The aerosol generation consumable according to any preceding claim, wherein the composition does not comprise any of cinnamon, chamomile, kudzu (pueraria lobata), amacha (hydrangeae dulcis folium), lavender, cardamom, caryophyllus, nutmeg, bergamot, geranium, honey essence, rose oil, cassia bark, caraway, jasmine, ginger, coriander, vanilla extract, spearmint, peppermint, cassia, coffee, celery, cascarilla, sandalwood, ylang ylang, fennel, anise, licorice, St John's bread, prune extract, peach extract, glucose, fructose, isomerized saccharide, caramel, cocoa powder, cocoa extract, isoamyl acetate, linalyl acetate, isoamyl propionate, linalyl butyrate, ionone, damascenone, ethyl maltol, geraniol, linalool, anethole, vanillin, benzaldehyde, anisaldehyde, y-undecalactone, y-nonalactone, musk, ambergris, civet, castoreum, limonene and pinene, or any extract thereof.

5. The aerosol generation consumable according to any preceding claim, wherein the or each of the one or more somatosensory compounds have a higher somatosensory labelled magnitude scale (LMS) value than the flavour and / or smell labelled magnitude scale value thereof.

6. The aerosol generation consumable according to any preceding claim, wherein the ratio of the somatosensory labelled magnitude scale value to the flavour and / or smell labelled magnitude scale value of the or each somatosensory compound is greater than 2:1 , such as 4:1 , such as 6:1 , such as 8:1 , such as 10:1 , such as 12:1, such as 14:1 , or even 16:1.

7. The aerosol generation consumable according to any preceding claim, wherein the composition further comprises tobacco which has been treated to reduce its flavour, and / or smell.

8. The aerosol generation consumable according to claim 7, wherein the tobacco is treated by heating and / or washing with solvents.

9. The aerosol generation consumable according to any preceding claim, wherein the composition further comprises nicotine.

10. An aerosol generation consumable according to any preceding claim, wherein the consumable comprises a liquid aerosol precursor material.

11. An aerosol generating consumable according to any preceding claim, wherein the consumable comprises a solid aerosol precursor material.

12. An aerosol generating consumable according to any preceding claim, wherein when the consumable comprises a liquid aerosol precursor material, the amount of the one or more somatosensory compounds present in the composition is from 1 to 15 wt.% of the total composition.

13. An aerosol generating consumable according to any preceding claim, wherein when the consumable comprises a solid aerosol precursor material, the amount of the one or more somatosensory compounds present in the composition is from 10,000 parts per million (ppm) to 50,000 ppm.

14. An aerosol generation device comprising the aerosol generation consumable according to any of the preceding claims.

15. Use of a somatosensory compound for providing a higher somatosensory effect than the flavour and / or smell effect thereof in an aerosol generation consumable or in an oral pouch, wherein the somatosensory compound is not nicotine.

16. The use according to claim 15, wherein the somatosensory compound is selected from alkyl isothiocyanates and / or linear or branched unsaturated aldehydes.

17. The use according to claim 15 or 16, wherein the somatosensory compound is selected from amyl isothiocyanate, isoamyl isothiocyanate, ethyl isothiocyanate, 2-ethyl-2-hexenal, 2,4-hexadienal or mixtures thereof.

18. An oral pouch comprising one or more somatosensory compounds, wherein the or each of the somatosensory compounds has a higher somatosensory effect than the flavour and / or smell effect thereof and wherein the or each of the somatosensory compounds is not nicotine.

19. An oral pouch according to claim 18, wherein the one or more somatosensory compounds are selected from amyl isothiocyanate, isoamyl isothiocyanate, ethyl isothiocyanate, 2-ethyl-2-hexenal, 2,4-hexadienal or mixtures thereof.

20. An oral pouch according to claim 18 or 19, wherein the somatosensory compound content in the oral pouch composition is from 0.08 to 5 wt.% of the total composition.

Citation Information

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