Medicine-powder measuring rod, medicine-powder measuring rod assembly, and medicine-powder measuring system

Abstract

Disclosed in the present application are a medicine-powder measuring rod, a medicine-powder measuring rod assembly, and a medicine-powder measuring system. The medicine-powder measuring rod comprises: a rod portion, which comprises a rod portion body, an operating section located at the proximal end of the rod portion body, and a measuring section located at the distal end of the rod portion body; and a dose tank, which is formed on the circumferential surface of the measuring section and is configured to accommodate a preset amount of medicine powder. When the rod is transferred by means of the operating section so as to be butt-joined to a simulated inhalation device, the dose tank comes into communication with a chamber inlet of the simulated inhalation device, such that an airflow carries the medicine powder in the dose tank to pass through the chamber inlet to a chamber outlet of the simulated inhalation device, thereby completing a test operation.

Description

Powder measuring rod, powder measuring rod assembly and powder measuring system Technical Field

[0001] The present application relates to the technical field of airflow analysis and testing of medicinal powders, and in particular to a medicinal powder measuring rod, a medicinal powder measuring rod assembly, and a medicinal powder measuring system. Background Art

[0002] Airflow analysis testing of drug powders can evaluate the inhalation performance of drugs. Airflow analysis testing of devices such as airflow drug dispensing devices (such as inhalers) can evaluate the performance of the device and the delivery and deposition of drugs in the respiratory system to ensure that patients can effectively inhale drug particles when using these devices.

[0003] However, airflow analysis testing for airflow-dispensing devices like inhalers requires both ensuring the dosage amount of powdered medicine and generating airflow. This results in limited sampling and consumable testing using the inhaler itself. This approach requires the entire development of the inhaler, resulting in a waste of resources. Many manufacturers even skip testing or perform only limited testing before shipping products, which can easily lead to suboptimal treatment outcomes for users.

[0004] Therefore, how to simulate this type of airflow distribution device for testing without using the device itself is an urgent problem to be solved by those skilled in the art. Summary of the Invention

[0005] In view of the shortcomings of the above-mentioned related technologies, the purpose of this application is to provide a powder measuring rod, a powder measuring rod assembly and a powder measuring system to overcome the technical problem in the above-mentioned related technologies that only consumable tests can be performed when performing airflow analysis tests on airflow-type drug dispensing devices.

[0006] To achieve the above-mentioned objectives and other related objectives, the present application provides a powder measuring rod in a first aspect, comprising: a rod including a rod body, an operating section located at the proximal end of the rod body, and a measuring section extending from the distal end of the rod body; a dosage groove formed on the circumferential surface of the measuring section, for accommodating a preset amount of powder; when the rod is transferred to a docking simulated inhalation device through the operating section, the dosage groove is connected to the chamber inlet of the simulated inhalation device so that an airflow carries the powder in the dosage groove from the chamber inlet to the chamber outlet of the simulated inhalation device to complete the testing operation.

[0007] The second aspect of the present application provides a powder measuring rod assembly, comprising: a first powder measuring rod and a second powder measuring rod, respectively used to accommodate a preset amount of first powder and a preset amount of second powder to cooperate with a simulated inhalation device to complete a testing operation; wherein each powder measuring rod is configured as a powder measuring rod as described in any embodiment disclosed in the first aspect of the present application.

[0008] The third aspect of the present application provides a powder measuring system, comprising: a powder measuring rod, which is configured as the powder measuring rod as described in any embodiment disclosed in the first aspect of the present application; a powder filling device, which is used to receive the powder measuring rod to fill the powder into the powder measuring rod; a transfer device, which is used to receive the powder measuring rod containing powder to store or transfer the powder measuring rod; and a simulated inhalation device, which is used to receive the powder measuring rod and dock with the powder measuring rod. During docking, the airflow carries the powder in the dosage slot of the powder measuring rod from the chamber inlet to the chamber outlet of the simulated inhalation device to complete the test operation.

[0009] In summary, the powder measuring rod, powder measuring rod assembly and powder measuring system provided by the present application, by setting up the powder measuring rod, can accommodate a preset amount of powder, thereby achieving the accuracy of the test dose; by setting up the powder filling device, it can achieve the filling of the preset amount of powder in the powder measuring rod, thereby further achieving the accuracy of the test; by setting up the transfer device, it can achieve the storage and transfer of the powder measuring rod, which can avoid the loss and contamination of the powder; by setting up the simulated inhalation device, it can achieve the formation of airflow and complete the docking with the powder measuring rod for drug distribution; through the synergistic effect of the powder measuring rod, the powder filling device, the transfer device and the simulated inhalation device, it can achieve airflow analysis testing of airflow distribution devices such as inhalers, thereby avoiding the consumable test of the inhaler itself. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] The specific features of the present application are set forth in the appended claims. The features and advantages of the present invention can be better understood by referring to the exemplary embodiments described in detail below and the accompanying drawings. A brief description of the drawings is as follows:

[0011] FIG1 is a schematic structural diagram of a powder measuring rod in one embodiment of the present application.

[0012] FIG2 is a schematic structural diagram showing an identification structure configured on a powder measuring rod in one embodiment of the present application.

[0013] FIG3 is a schematic diagram showing the proximal end surface of a powder measuring rod in one embodiment of the present application.

[0014] FIG4 is a schematic diagram showing the proximal end surface of a powder measuring rod in one embodiment of the present application.

[0015] FIG5 is a schematic diagram showing a powder measuring rod assembly according to an embodiment of the present application.

[0016] FIG6 is a schematic diagram showing a proximal end surface of a powder measuring rod assembly in one embodiment of the present application.

[0017] FIG7 is a schematic structural diagram of a medicine powder filling device in one embodiment of the present application at one viewing angle.

[0018] FIG8 is a schematic structural diagram of a medicine powder filling device in one embodiment of the present application from another perspective.

[0019] FIG9 is a schematic structural diagram showing a configurable tray for a powder filling device according to an embodiment of the present application.

[0020] FIG. 10 is a schematic diagram showing a medicine powder filling assembly in one embodiment of the present application.

[0021] FIG11 is a schematic structural diagram of a transfer device in one embodiment of the present application.

[0022] FIG12 is a schematic diagram showing the disassembled structure of the transfer device in one embodiment of the present application.

[0023] FIG13 is a schematic diagram showing a process in which the frame moves relative to the base to lock the powder measuring rod in one embodiment of the present application.

[0024] FIG. 14 is a schematic structural diagram of a simulated inhalation device according to an embodiment of the present application.

[0025] FIG15 is a cross-sectional schematic diagram showing a manifold configured in a main body in one embodiment of the present application.

[0026] FIG. 16 is a schematic diagram showing the release of the fixing mechanism and the positioning plate of the simulated inhalation device according to one embodiment of the present application.

[0027] FIG. 17 is a schematic diagram showing the engagement between the fixing mechanism and the positioning plate of the simulated inhalation device according to one embodiment of the present application.

[0028] FIG. 18 is a cross-sectional view of a simulated inhalation device without a manifold installed according to an embodiment of the present application.

[0029] FIG19 is a schematic structural diagram of the simulated inhalation device in one embodiment of the present application from another perspective.

[0030] FIG. 20 is a cross-sectional view of a simulated inhalation device according to an embodiment of the present application.

[0031] FIG. 21 is a schematic diagram showing the process of docking the simulated inhalation device with the powder measuring rod in one embodiment of the present application. DETAILED DESCRIPTION

[0032] The following is a description of the implementation of the present application through specific embodiments. People familiar with this technology can easily understand the advantages of the present application and the technical effects that can be achieved from the contents disclosed in this specification.

[0033] In the following description, some embodiments may be referred to the accompanying drawings. It should be understood that other embodiments without accompanying drawings may also be used, and that specific structures, parts or mechanisms, components, and operational changes may be made without departing from the spirit and scope of the present application. The following detailed description should not be considered restrictive, and the scope of the embodiments of the present application is limited only by the claims published in this application. The terms used herein are only for the purpose of describing specific embodiments and are not intended to limit the present application.

[0034] Although in some instances the terms first, second, etc. are used herein to describe various elements or parameters, these elements or parameters should not be limited by these terms. These terms are only used to distinguish one element or parameter from another. For example, the first powder measuring rod can be referred to as the second powder measuring rod, and similarly, the second powder measuring rod can be referred to as the first powder measuring rod without departing from the scope of the various described embodiments. The first powder measuring rod and the second powder measuring rod are both describing a certain powder measuring rod, but unless the context clearly indicates otherwise, they are not the same powder measuring rod. Similar situations also include the first recess and the second recess, the first powder and the second powder, etc.

[0035] Furthermore, as used in this article, the singular forms "one", "an" and "the" are intended to also include plural forms, unless there is an indication to the contrary in the context. It should be further understood that the terms "comprising" and "including" indicate the presence of described features, steps, operations, elements, components, projects, kinds, and / or groups, but do not exclude the existence, occurrence or addition of one or more other features, steps, operations, elements, components, projects, kinds, and / or groups. For example, a process, method, system, product or device comprising a series of steps or units need not be limited to those steps or units clearly listed, but may include other steps or units that are not clearly listed or that are inherent to these processes, methods, products or devices. In addition, the term "and / or" that may be used hereinafter describes the association relationship of associated objects, indicating that three relationships may exist, for example, A and / or B can represent: A exists alone, A and B exist simultaneously, and B exists alone. In addition, the character " / ", if not otherwise specified, generally represents that the associated objects before and after are a kind of "and / or" relationship. In addition, in the description of the embodiments of the present application, "a plurality" refers to two or more than two. Furthermore, the terms "or" and "and / or" used in this document are interpreted as inclusive, or mean any one or any combination. Exceptions to this definition will only occur when a combination of elements, functions, steps or operations are inherently mutually exclusive in some way.

[0036] It will also be understood that when an element, such as a layer, region, or substrate, is referred to as being “on” or extending “over” another element, the element may be directly on or directly extending over the other element, or intervening elements may be present. Conversely, when an element is referred to as being “directly on” or “extending directly over” another element, there are no intervening elements present. It will also be understood that when an element is referred to as being “connected” or “coupled” to another element, it may be directly connected or coupled to the other element, or there may be intervening elements present. Conversely, when an element is referred to as being “directly connected” or “directly coupled” to another element, there are no intervening elements present.

[0037] Relative terms such as "below" or "above" or "upper" or "lower" or "horizontal" or "vertical" may be used herein to describe the relationship of one element, layer or region to another element, layer or region as illustrated in the figures. It will be understood that these terms are intended to cover different device orientations other than the orientation depicted in the figures. In this application, the "vertical", "horizontal" and "parallel" are defined as including situations within ±10% of the standard definition. For example, vertical usually refers to an angle of 90° relative to a reference line, but in this application, vertical refers to situations within 80° to 100°. Unless otherwise expressly stated, comparative quantitative terms (such as "above" and "below") are intended to cover the concept of equality. As an example, "above" can mean not only "greater than" in a mathematical sense, but also "equal to".

[0038] Unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. It will also be understood that the terms used herein should be interpreted as having a meaning consistent with their meaning in the context of this specification and the relevant art, and should not be interpreted in an idealized or overly formal sense unless explicitly defined as such in this document.

[0039] In view of the technical problems mentioned in the background technology, the present application discloses a powder measuring rod, a powder measuring rod assembly, a powder filling device, a powder filling assembly, a transfer device, a transfer assembly, a simulated inhalation device and a powder measuring system. By setting up the powder measuring rod, it is possible to accommodate a preset amount of powder, thereby achieving the accuracy of the test dose; by setting up the powder filling device, it is possible to fill the powder measuring rod with a preset amount of powder, thereby further achieving the accuracy of the test; by setting up the transfer device, it is possible to store and transfer the powder measuring rod, which can avoid the loss and contamination of the powder; by setting up the simulated inhalation device, it is possible to form an airflow and complete the docking with the powder measuring rod for drug distribution; through the synergistic effect of the powder measuring rod, the powder filling device, the transfer device and the simulated inhalation device, it is possible to achieve airflow analysis testing of airflow distribution devices such as inhalers, thereby avoiding the consumable test of the inhaler itself.

[0040] In order to clearly illustrate the positional relationship of the various components, structures, components, mechanisms, equipment, or devices in the embodiments of the present application, in a general state of use, the side close to the operator is defined as the proximal end (also referred to as the proximal side, the front side, or the front end, etc.), the side away from the operator is defined as the distal end (also referred to as the distal side, the rear side, or the rear end, etc.), the side located to the right of the operator is defined as the right side (also referred to as the right side, the right side, etc.), and the side located to the left of the operator is defined as the left side (also referred to as the left side, the left side, etc.). The side close to the operating platform (also referred to as the support surface, the operating surface, etc.) is defined as the lower side or the bottom, and the side away from the operating platform is defined as the upper side or the top, and the plane where the operating platform is located is defined as the horizontal plane (also referred to as the horizontal direction), and the plane perpendicular to the horizontal plane is defined as the vertical plane (also referred to as the vertical plane, the vertical direction, or the vertical direction). It should be understood that the orientation defined here does not represent an absolute position, but refers to a relative position.

[0041] The operator refers to a person or machine that operates various components, structures, assemblies, mechanisms, equipment, or devices. The person may be, for example, a professional responsible for performing analytical tests, collecting data, or ensuring the accuracy and smoothness of the testing process. For example, they may be a test engineer, laboratory technician, or data collector. The machine may, for example, include a robotic arm. The subsequent embodiments will be described using a human operator as an example, and this should not be construed as limiting the present application.

[0042] The operating platform refers to a platform or workbench used to place or support these components, structures, components, mechanisms, equipment, or devices, which can be, for example, a table, a laboratory table, a weighing table, etc.

[0043] In some embodiments, the present application discloses a powder measuring system, comprising a powder measuring rod, a powder filling device, a transfer device, and a simulated inhalation device. It should be noted that the powder measuring system disclosed in the present application does not limit the number and type of the powder measuring rod, powder filling device, transfer device, and simulated inhalation device included. For example, in some embodiments, the powder measuring system may also include a powder measuring rod assembly, a powder filling assembly, a transfer assembly, and a simulated inhalation device, wherein the powder measuring rod assembly includes at least two powder measuring rods, the powder filling assembly includes at least two powder filling devices, and the transfer assembly includes at least two transfer devices.

[0044] The powder measuring rod and rod assembly, the powder filling device and filling assembly, the transfer device and transfer assembly, and the simulated inhalation device disclosed in the present application are described below in conjunction with the embodiments shown in Figures 1 to 21.

[0045] The present application discloses a powder measuring rod in some embodiments, which is used to accommodate a preset amount of powder. Please refer to Figure 1, which shows a schematic structural diagram of a powder measuring rod in one embodiment of the present application. As shown in Figure 1, the powder measuring rod 1 includes a rod 11 and a dosage slot 12. The rod 11 further includes a rod body 110, an operating section 111, and a measuring section 112. The operating section 111 is located at the proximal end of the rod body 110, and the measuring section 112 is located at the distal end of the rod body 110. The dosage slot 12 is provided on the circumference of the measuring section 112 and is used to accommodate a preset amount of powder. When the rod 11 is transferred to the docking simulated inhalation device through the operating section 111, the dosage slot is connected to the chamber inlet of the simulated inhalation device so that the airflow carrying the powder in the dosage slot is guided from the chamber inlet to the chamber outlet of the simulated inhalation device to complete the test operation. The structure of the simulated inhalation device will be described in detail later.

[0046] The shape of the rod 11 shown in Figure 1 is only a schematic representation. In the embodiment, the rod includes but is not limited to a straight rod and a curved rod, and its cross-section includes but is not limited to a circular, quasi-circular, polygonal and quasi-polygonal shape, as long as it can adapt to the device or equipment for its insertion or docking.

[0047] The operating section provides an operating space for the operator. The operator can grasp the operating section to operate the powder measuring rod, for example, by transferring, placing, inserting, rotating, docking, and other operations that require contact with the rod. In one embodiment, the operating section can be configured as a handle located at the proximal end of the rod body, which the operator manipulates to operate the powder measuring rod. In one embodiment, as shown in Figure 1, the operating section 111 is configured to extend from the proximal end of the rod body. The operator can grasp this portion to operate the powder measuring rod 1, for example, by grasping this portion with the operator's fingers.

[0048] In one embodiment, as shown in FIG1 , the operating section 111 is provided with a gripping portion 113 for manipulating the rod 11. That is, the operator can operate the powder measuring rod 1 by gripping the gripping portion 113. Furthermore, the gripping portion 113 can be configured as a recessed structure formed on the circumference of the operating section 111, providing a gripping space where the operator's fingers can be positioned. In one example, the recessed structure is configured as a recessed portion formed downwardly on the circumference of the operating section, where the operator's fingers can be positioned for ease of operation. In another example, the recessed structure can also include a first recessed portion and a second recessed portion, with the first and second recessed portions being arranged relative to each other on the circumference of the operating section for gripping. For example, the operator's thumb can be placed in the first recessed portion, and the index or middle finger can be placed in the second recessed portion, to facilitate gripping and transferring the powder measuring rod. For example, the first and second recesses can be relatively distributed left and right around the perimeter of the operating section, or relatively distributed up and down around the perimeter of the operating section. It should be understood that the grip portion 113 can be located anywhere on the operating section 111 as long as it allows the operator to grip it. Of course, the grip portion 113 can also be omitted, and the operator can grip directly on the operating section.

[0049] In one embodiment, referring again to FIG. 1 , the measuring section 112 can be configured as an extension formed along the distal end of the rod body 110, and the dose groove 12 can be configured as a groove formed by the measuring section 112 being recessed downward. Of course, in other embodiments, the measuring section can also be configured as a component connected to the distal end of the rod body, and the dose groove can be a portion of the measuring section.

[0050] As mentioned above, the dose slot 12 is used to accommodate a preset amount of medicinal powder. For example, the medicinal powder may refer to a single-component medicinal powder or a mixed medicinal powder used to treat asthma and other inflammatory diseases of the respiratory system, such as atropine, budesonide and salmeterol, or any combination thereof. The preset amount refers to a single dose that can produce a therapeutic effect of the drug or a single dose of a single component in a mixed medicinal powder that produces a therapeutic effect. In one embodiment, the preset amount can be configured to any value not greater than 30μl, such as 5μl, 8μl, 10μl, 15μl, 18μl, 20μl, 25μl, 30μl, etc. Preferably, the preset amount is configured to be 5μl to 20μl. It should be understood that the size of the dose slot to be set can be obtained based on the capacity of the dose slot corresponding to the preset amount and the shape of the dose slot.

[0051] In one embodiment, as shown in FIG1 , the dosage slot 12 is configured to have a nearly elliptical opening. In other embodiments, the dosage slot may be configured to have a circular opening, a square opening, or a V-shaped opening, but is not limited thereto, and is specifically selected based on actual needs and the manufacturer's design.

[0052] To facilitate the drop of powder to the bottom of the dose slot, in one embodiment, the dose slot 12 is configured as a slot structure with a continuously decreasing cross-section from top to bottom, such as a funnel shape. This structure not only facilitates the filling of powder into the dose slot, but also more closely resembles the structure of a medicine sachet in an inhaler, enabling the airflow to carry the powder during the analysis and testing process in a manner more similar to that of a real device, thereby improving the accuracy of the test. Of course, the slot structure can also be configured as other shapes, as long as it has a volume that accommodates the preset amount of powder and is compatible with the simulated inhalation device.

[0053] Please refer to Figure 2, which shows a schematic diagram of an identification structure configured on a powder measuring rod according to one embodiment of the present application. As shown, the rod 11 is provided with an identification structure 115 for providing instructions to the operator. In one example, the identification structure can be used to indicate the type of powder measuring rod. The type of powder measuring rod refers to different powder measuring rods. For example, the identification structure can distinguish the type of powder contained in the dose slot. In another example, the identification structure can be used to indicate the status of the powder measuring rod. The status of the powder measuring rod refers to the current state of the powder measuring rod used by the operator to perform an operation, such as the placed state or the docked state. It should be understood that the placed state refers to the state of the powder measuring rod when placed on a horizontal surface, with the dose slot opening facing upward and the identification structure tilted. The docked state refers to the state of the powder measuring rod when it is docked with the simulated inhalation device. In one example, the identification structure can indicate both the type of the powder measuring rod and the status of the powder measuring rod.

[0054] The identification structure includes but is not limited to color identification, number identification, letter identification, or any combination of the above visual identification. The identification structure is configured on the rod in a manner including but not limited to pasting, engraving, labeling, laser engraving and digital display screen. Furthermore, in order to facilitate observation by operators, the identification structure can be configured on the end face of the proximal end of the rod.

[0055] In embodiments where the identification structure is configured as a letter identifier, the letter corresponding to the letter identifier can be used to indicate the type of powder measuring rod. When different types of powders are used for analysis and testing, or when powders from different powder measuring rods need to be mixed during analysis and testing, the letter identifier can provide a convenient visual indication to the operator. By observing the letter identifier, the operator can determine which powder type is contained in the powder measuring rod, thereby avoiding confusion. For example, as shown in FIG2 , the letter A can be marked on the end face of rod 11 of a powder measuring rod 1 to indicate that its dose slot 12 contains a preset amount of the first powder. The letter B can be marked on the end face of another powder measuring rod to indicate that its dose slot contains a preset amount of the second powder. Thus, the operator can distinguish between the two powder measuring rods by the letters A and B.

[0056] In an embodiment where the marking structure is configured as a letter marking, the position of the letter corresponding to the letter marking can indicate the status of the powder measuring rod. When the powder measuring rod is placed on a horizontal surface, the letter marking is at a preset angle to the vertical. When the powder measuring rod is docked, the letter marking rotates from the preset angle to an upright position to indicate proper docking. The rotation of the letter marking during the docking state will be described in detail later.

[0057] Please refer to Figure 3, which shows a schematic diagram of the proximal end face of a powder measuring rod according to one embodiment of the present application. For ease of illustration, the dose slot, which is not visible from the proximal end face, is shown in dashed lines. As shown, the marking structure 115 is configured to have a predetermined angle relative to the perpendicular direction of the dose slot 12. The predetermined angle refers to the angle α between the direction of the letter corresponding to the letter marking and the perpendicular direction of the dose slot 12. The predetermined angle can be positive or negative. A positive angle indicates a clockwise rotation from the perpendicular direction of the dose slot 12 (as indicated by the predetermined angle α in Figure 3), while a negative angle indicates a counterclockwise rotation from the perpendicular direction of the dose slot 12. In the embodiment shown in Figure 3, the predetermined angle α is set to 45°, indicating that the letter A is rotated 45° clockwise from the perpendicular direction of the dose slot 12. Of course, the predetermined angle α can also be set to -45°, indicating that the letter A is rotated 45° counterclockwise from the perpendicular direction of the dose slot 12. It should be understood that the above-mentioned 45° or -45° is only an example, and those skilled in the art can also configure it to other angles, such as 30°, -30°, 60°, -60°, etc., based on the guidance of this application.

[0058] In one embodiment, the powder measuring rod has a preset length, which is used to indicate the type of powder measuring rod. The preset length refers to a pre-set length of the powder measuring rod. When different types of powders are used for analysis and testing, or when powders from different powder measuring rods need to be mixed during analysis and testing, the preset length can provide a convenient visual indication to the operator. By observing the length of the powder measuring rod, the operator can determine which type of powder is contained in the powder measuring rod, thereby avoiding confusion. For example, a relatively shorter preset length of the powder measuring rod can indicate that the dose slot contains a preset amount of a first powder, while a relatively longer preset length can indicate that the dose slot contains a preset amount of a second powder. Thus, the operator can distinguish between the two powder measuring rods based on the preset length of the rod.

[0059] In another embodiment, different preset lengths also serve to facilitate the operator's operation when the powder measuring rod is docked with the simulated inhalation device, which function will be described in detail later.

[0060] It should be noted that the powder measuring rod can be used to indicate the type of powder by using either a different letter mark or a different preset length, or both methods can be used simultaneously to minimize operator confusion. Of course, other variations are possible, such as using different colors on the rod or end surface. As long as the type of powder within the rod can be distinguished, the invention is protected by this application.

[0061] As shown in Figure 1 , the powder measuring rod 1 also includes a positioning portion 114 disposed on the bottom side of the rod 11. This positioning portion 114 is used to support the rod 11 so that the opening of the dose slot 12 faces upward when the rod 11 is placed on a horizontal surface. This also provides for more stable placement of the powder measuring rod 1 on the workbench, preventing it from tipping over or falling over. Please refer to Figure 4 in conjunction with Figure 1 , which shows a schematic diagram of the proximal end face of the powder measuring rod according to one embodiment of the present application. For ease of illustration, the dose slot, which is not visible from the proximal end face, is shown in dashed lines. As shown, the positioning portion 114 is configured to have a predetermined angle relative to the perpendicular direction of the dose slot 12. The predetermined angle is defined as the angle β between the axis of the positioning portion 114 and the perpendicular direction of the dose slot 12. The predetermined angle can be positive or negative. A positive angle indicates clockwise rotation from the perpendicular direction of the dose slot 12, while a negative angle indicates counterclockwise rotation from the perpendicular direction of the dose slot 12. As shown in FIG4 , the preset angle β is configured as −60°, indicating that the axis direction of the positioning portion 114 is rotated 60° counterclockwise from the vertical direction of the dose slot 12. Of course, the preset angle β can also be configured as 60°, indicating that the axis direction of the positioning portion 114 is rotated 60° clockwise from the vertical direction of the dose slot 12.

[0062] In one embodiment, as shown in Figures 1 to 4, the positioning portion 114 is configured as a cylindrical structure protruding circumferentially from the rod 11. The cylindrical structure can be integrally formed with the rod 11. When the powder measuring rod is placed on a horizontal surface, the cylindrical structure provides point support for the rod 11. In another embodiment, the positioning portion can be configured as a raised point structure protruding circumferentially from the rod. In yet another embodiment, the positioning portion may not be provided. For example, the structure and center of gravity of the powder measuring rod can be taken into consideration when designing the powder measuring rod, so that when the opening direction of the dose slot is vertical, the powder measuring rod automatically maintains a balanced state. In this case, the powder measuring rod can be stably placed on a horizontal surface without the need for a positioning portion.

[0063] In order to implement multi-channel testing of drug powder or implement a powder mixing test in an airflow analysis test, it is necessary to accommodate different drug powders in different drug powder measuring rods. In view of this, the present application discloses a drug powder measuring rod assembly in some embodiments. Please refer to Figure 5, which shows a schematic diagram of a drug powder measuring rod assembly in one embodiment of the present application. As shown in Figure 5, the drug powder measuring rod assembly includes a first drug powder measuring rod 1 and a second drug powder measuring rod 2. The first drug powder measuring rod 1 is used to accommodate a preset amount of first drug powder, and the second drug powder measuring rod 2 is used to accommodate a preset amount of second drug powder, thereby cooperating with the simulated inhalation device to complete the test operation. For example, the first drug powder measuring rod 1 and the second drug powder measuring rod 2 can be respectively configured as the drug powder measuring rods described in any embodiment of Figures 1 to 4 and their related descriptions.

[0064] The first or second medicinal powder may be configured as a medicinal powder for treating asthma or other inflammatory diseases of the respiratory system. In one example, the first medicinal powder is configured to contain a bronchodilator as an active pharmaceutical ingredient, and the second medicinal powder is configured to contain an anti-inflammatory drug as an active pharmaceutical ingredient.

[0065] To enable operators to distinguish between the first and second powders contained in the first and second powder measuring rods of the powder measuring rod assembly, in one embodiment, as shown in FIG5 , the letter marking on the proximal end surface of the first powder measuring rod 1 is configured as the letter A, and the letter marking on the proximal end surface of the second powder measuring rod 2 is configured as the letter B. Of course, the letter marking on the proximal end surface of the first powder measuring rod 1 can be configured as the letter C, and the letter marking on the proximal end surface of the second powder measuring rod 2 can be configured as the letter D. This application does not impose any restrictions on this, as long as the first and second powder measuring rods can be distinguished, and thus the first and second powders contained therein can be further distinguished.

[0066] Furthermore, the predetermined angle of the marking structure on the first powder measuring rod 1 relative to the vertical direction of its dose slot 12 is configured to be opposite to the predetermined angle of the marking structure on the second powder measuring rod 2 relative to the vertical direction of its dose slot 22. In the embodiment shown in FIG5 , the predetermined angle of the letter A on the first powder measuring rod 1 relative to the vertical direction of its dose slot 12 is 45°, while the predetermined angle of the letter B on the second powder measuring rod 2 relative to the vertical direction of its dose slot 22 is -45°, with the two being in opposite directions.

[0067] In one embodiment, the first powder measuring rod 1 and the second powder measuring rod 2 have different preset lengths, and the preset length of the second powder measuring rod 2 is longer than that of the first powder measuring rod 1. For example, in the embodiment shown in FIG5 , the preset length L1 of the first powder measuring rod 1 is less than the preset length L2 of the second powder measuring rod 2. The preset length L2 of the second powder measuring rod 2 can differ from the preset length L1 of the first powder measuring rod by any value between 16 mm and 20 mm, such as 16 mm, 16.3 mm, 16.5 mm, 17 mm, 18 mm, 19 mm, 20 mm, etc. Thus, from the operator's perspective, the first powder measuring rod 1 appears short and thick, while the second powder measuring rod 2 appears slender and long. It should be understood that the preset length identification shown in Figure 5 is only a schematic illustration and does not mean that the preset lengths of the rods in the two powder measuring rods are necessarily equal or unequal. For example, the relationship between the preset length L1 of the first powder measuring rod 1 and the preset length L2 of the second powder measuring rod 2 may also be L1>L2 or L1=L2, etc.

[0068] In one embodiment, the predetermined angle of the first powder measuring rod's positioning portion relative to the perpendicular direction of its dose slot is configured to be opposite to the predetermined angle of the second powder measuring rod's positioning portion relative to the perpendicular direction of its dose slot. Please refer to Figure 6 in conjunction with Figure 5 , which shows a schematic diagram of the proximal end face of a powder measuring rod assembly according to one embodiment of the present application. As shown in Figure 6 , the predetermined angle β of the positioning portion 114 of the first powder measuring rod 1 relative to the perpendicular direction of its dose slot 12 is -60°, while the predetermined angle β of the positioning portion 214 of the second powder measuring rod 2 relative to the perpendicular direction of its dose slot 22 is 60°.

[0069] Based on any one or a combination of the differences between the first and second powder measuring rods, an operator can easily distinguish the first and second powder measuring rods 1 and 2 , thereby easily distinguishing the first and second powders contained therein.

[0070] In order to be able to fill a preset amount of medicine powder onto the powder measuring rod, for example, to fill the dosage slot in the powder measuring rod described in any of the aforementioned embodiments with medicine powder so that it contains a preset amount of medicine powder, the present application, in some embodiments, further discloses a medicine powder filling device. By arranging a accommodating cavity and a feed port on the main body, the medicine powder measuring rod can be placed in the accommodating cavity and the medicine powder can be filled through the feed port, so that the medicine powder can be accurately filled into the dosage slot.

[0071] Please refer to Figure 7, which is a schematic structural diagram of a powder filling device in one embodiment of the present application at a certain viewing angle. As shown in Figure 7, the powder filling device 3 includes a main body 31 and a feed port 32. The main body 31 is provided with a receiving chamber 33, and the receiving chamber 33 is used to receive a powder measuring rod. The feed port 32 is arranged on the main body 31 and is connected to the receiving chamber 33. When the powder measuring rod is placed in the receiving chamber 33, the dosage groove on the powder measuring rod faces the feed port 32 so that the powder falls into the dosage groove through the feed port 32. It should be noted that in order to distinguish it from the receiving chambers in other subsequent devices or components, in the embodiment, the receiving chamber included in the powder filling device is also referred to as a first receiving chamber.

[0072] As shown in FIG7 , in one embodiment, the body 31 includes a base 311 and a filling portion 312. The base 311 provides a support foundation, and it can also be understood that the filling portion 312 is supported on the base 311. In one embodiment, as shown in FIG7 , the base 311 is configured as a generally rectangular base, and further, it can be flat, thereby providing stable support. To avoid bumping into the operator, in the example shown in FIG7 , the upward edge of the base is configured as a curved edge or an edge of an inclined surface.

[0073] In one embodiment, as shown in FIG7 , the filling portion 312 is configured as a generally rectangular main body portion, whose width is less than the width of the base 311 and whose height is significantly greater than the height of the base 311. Furthermore, to avoid bumping into the operator, the edges of the base facing upward and on the left and right sides can be configured as curved edges or edges of inclined surfaces. In some examples, the filling portion 312 and the base 311 can be integrally formed or connected by a fixed connection method, and the fixed connection method includes but is not limited to welding, bonding, and mortise and tenon joints. In certain other examples, the main body of the powder filling device may not distinguish between a base and a filling portion, and this application does not impose any restrictions on this.

[0074] In one embodiment, as shown in FIG7 , the first accommodating cavity 33 and the feed port 32 are formed on the filling portion 312 of the body 31 . Please refer to FIG8 , which shows a schematic structural diagram of the powder filling device according to one embodiment of the present application from another perspective. As shown in FIG7 and FIG8 , the first accommodating cavity 33 is formed on the filling portion 312 in a front-to-back manner, and the feed port 32 extends vertically at the top (or upper portion) of the filling portion 312 to communicate with the first accommodating cavity 33 . To facilitate the descent of the powder into the dosage trough, in one example, the feed port 32 is configured as a hole structure with a continuously decreasing cross-section from top to bottom. For example, it may be a funnel-shaped hole structure, a trumpet-shaped hole structure, or another hole structure with inclined sidewalls. Of course, the feed port can also be configured as other shapes as long as it allows the powder to enter the dosage trough.

[0075] In one embodiment, the first accommodating chamber 33 includes a rod receiving chamber 331 for inserting a rod of a powder measuring rod. In one example, the rod receiving chamber 331 is formed on the filling portion 312 in a front-to-back through-hole configuration. It should be noted that, to distinguish it from rod receiving chambers included in accommodating chambers in other devices or components, in this embodiment, the rod receiving chamber included in the first accommodating chamber is also referred to as the first rod receiving chamber. Similarly, in subsequent embodiments, the positioning groove further included in the first accommodating chamber is also referred to as the first positioning groove, and subsequent references to the positioning groove further included in the first accommodating chamber will not be repeated.

[0076] In one embodiment, the depth of the first rod receiving chamber 331 is smaller than the length of the rod in the powder measuring rod, so that when the rod is inserted, its operating section protrudes from the first rod receiving chamber 331, thereby facilitating the operator to hold the operating section to insert or pull out the powder measuring rod from the first rod receiving chamber 331.

[0077] In one embodiment, the first rod receiving chamber 331 is sized to fit snugly with the rod of the powder measuring rod, preventing any excess powder from being removed by the rod when the rod is removed. This means that the diameter of the first rod receiving chamber 331 is substantially the same as the diameter of the rod. After powder is filled into the dosage slot of the powder measuring rod from the feed inlet 32, when the operator removes the rod by gripping the operating section, the first rod receiving chamber 331 acts as a scraper, scraping any excess powder from the rod due to the limited size of the first rod receiving chamber 331 and the rod. This eliminates the need for the operator to precisely weigh the powder to be filled; they can simply roughly fill the dosage slot to ensure the correct amount of powder, thereby improving the efficiency of powder filling and, consequently, the testing process.

[0078] In one embodiment, the first accommodating chamber 33, in addition to including the first rod receiving chamber 331, may further include a first positioning groove 332. The first positioning groove 332 is disposed circumferentially around the first rod receiving chamber 331 and is configured to cooperate with the positioning portion of the powder measuring rod so that when the positioning portion reaches the end of the first positioning groove 332, the dosage groove of the powder measuring rod is aligned with the feed inlet 32. In other words, the first positioning groove 332, in conjunction with the positioning portion of the powder measuring rod, limits the insertion depth of the powder measuring rod. When an operator inserts a suitable powder measuring rod into the first accommodating chamber 331 by manipulating the operating section of the powder measuring rod, the positioning portion reaches the end of the first positioning groove 332, preventing the rod from being pushed any further. At this point, the dosage groove of the powder measuring rod is aligned with the feed inlet 32, thereby facilitating insertion of the powder measuring rod into the desired position.

[0079] In one embodiment, the first positioning groove 332 is configured to have a preset angle relative to the vertical direction of the feed port 32, and the preset angle is consistent with the preset angle of the positioning portion on the powder measuring rod relative to the vertical direction of the dosage slot. For example, when the preset angle between the axial direction of the positioning portion of the powder measuring rod and the vertical direction of the dosage slot is -60°, the preset angle between the axial direction of the first positioning groove 332 of the powder filling device 3 and the vertical direction of the feed port 32 is also -60°; when the preset angle between the axial direction of the positioning portion of the powder measuring rod and the vertical direction of the dosage slot is 60°, the preset angle between the axial direction of the first positioning groove 332 of the powder filling device 3 and the vertical direction of the feed port 32 is also 60°. In this way, on the one hand, it can be ensured that when the rod is inserted into the first accommodating cavity 33, the first positioning groove 332 of the powder filling device 3 is perpendicular to the feed port 32. A positioning groove 332 is engaged with the positioning portion to position the powder measuring rod; on the other hand, it can prevent the operator from inserting a powder measuring rod that is not compatible with the powder filling device 3 into the first accommodating chamber 33, thereby preventing the operator from incorrectly filling the powder. For example, when the axial direction of the first positioning groove 332 of the powder filling device 3 is at a preset angle of -60° to the vertical direction of the feed port 32, the operator cannot insert the powder measuring rod with a preset angle of 60° between the axial direction of the positioning portion and the vertical direction of the dosage slot into the first accommodating chamber 33.

[0080] In one embodiment, the depth of the first positioning groove 332 is configured to accommodate the dimensions of the feed inlet, the positioning portion of the powder measuring rod, and the dosage groove. This limits both the angle and depth of the first positioning groove 332, ensuring that when the powder measuring rod is inserted into the first accommodating chamber 33, the dosage groove on the powder measuring rod is aligned with the feed inlet 32 ​​of the powder filling device 3. That is, the axis of the dosage groove opening coincides with the axis of the feed inlet, facilitating accurate filling of powder from the feed inlet 32 ​​into the dosage groove. In a preferred embodiment, the depth of the first positioning groove 332 is 10 mm.

[0081] In the embodiment shown in FIG7 , the body 31 of the powder filling device 3 is provided with an identification structure 35. The identification structure 35 is used to indicate the type of powder filling device. The type of powder filling device refers to different powder filling devices. Furthermore, the identification structure 35 can distinguish the type of powder to be filled.

[0082] The identification structure includes but is not limited to color identification, number identification, letter identification, or any combination of the above visual identification. The way of configuring the identification structure on the main body includes but is not limited to pasting, engraving, labeling, laser engraving and digital display screen. Furthermore, in order to facilitate observation by operators, the identification structure can be configured on the end face of the proximal end of the main body.

[0083] In embodiments where the marking structure is configured as a letter marking, when different powder measuring rods need to be filled with different powders, the letters can provide a convenient visual indication to the operator. By observing the letters, the operator can determine which powder to fill into the feed port, thereby avoiding confusion. For example, as shown in FIG7 , the letter marking A on the proximal end surface of the body 31 of the powder filling device 3 can instruct the operator to fill the first powder into the feed port 32, while the letter marking B on the proximal end surface of the body of another powder filling device can instruct the operator to fill the second powder into its feed port. Thus, the operator can distinguish between the two powders to be filled by the letters A and B.

[0084] Of course, the identification structure can be set at any position of the powder filling device, as long as the operator can clearly realize the type of powder to be filled, and this application does not impose any restrictions on this.

[0085] The following describes the operation process of filling a powder measuring rod configured as the powder measuring rod 1 shown in FIG. 2 into the powder filling device shown in FIG. 7 , taking the powder measuring rod 1 as an example.

[0086] First, the operator grasps the operating section 111 on the powder measuring rod 1 and inserts the rod body 110 into the first rod receiving chamber 331 in the powder filling device 3 with the letter mark A, which is consistent with the letter mark A of the powder measuring rod 1. During this process, the positioning part 114 on the powder measuring rod 1 is aligned with the first positioning groove 332 on the powder filling device 3 and inserted to the deepest. At this time, the dosage groove 12 on the powder measuring rod 1 is aligned with the feed port 32 on the powder filling device 3, waiting for the operator to perform subsequent powder filling operations.

[0087] To recycle excess powder after filling and avoid powder waste, please refer to FIG9 , which illustrates a schematic diagram of a powder filling device configured with a tray in one embodiment of the present application. As shown, the powder filling device 3 further includes a tray receiving chamber 34 for receiving a tray 5 to receive excess powder. Furthermore, the tray receiving chamber 34 can be formed by an opening on the distal end surface of the body 31 extending into the interior of the body 31. The opening is located below and communicates with the first accommodating chamber 33. Specifically, a through-hole G can be provided at the bottom of the first accommodating chamber 33, connecting the tray receiving chamber 34 with the first accommodating chamber 33. Thus, when the tray 5 is placed in the tray receiving chamber 34, the powder receiving portion of the tray 5 faces the through-hole G. When the powder measuring rod is filled with powder through the feed port 32 and then removed, excess powder can fall through the through-hole G into the powder receiving portion of the tray 5.

[0088] In one embodiment, as shown in FIG8 , the tray receiving chamber 34 includes a first foolproof structure 341. For example, the first foolproof structure 341 can be configured as a recessed area on the lower side wall of the tray receiving chamber 34, with the opening of the recessed area constituting a portion of the opening on the tray receiving chamber 34, thereby allowing a matching portion of the tray 5 to be inserted.

[0089] Continuing with Figure 9 , the tray 5 includes a tray body 52, which is inserted through the opening of the tray receiving chamber 34. Furthermore, the tray 5 may also include a second foolproof structure 51 that mates with the first foolproof structure 341. The second foolproof structure 51 is disposed below the tray body 52. ​​In the example shown in Figure 9 , the second foolproof structure 51 is configured as a protruding block structure on the bottom of the tray body 52.

[0090] As shown in Figure 9, the second foolproof structure 51 mates with the first foolproof structure 341, ensuring that the tray 5 can only be inserted into the tray receiving chamber 34 in the correct manner, thereby preventing operator installation errors. Specifically, when the operator installs the tray 5 into the tray receiving chamber 34, the protrusion corresponding to the second foolproof structure 51 on the tray 5 must be aligned with the depression corresponding to the first foolproof structure 341 in the tray receiving chamber 34.

[0091] In other embodiments, the first fool-proofing structure 341 and the second fool-proofing structure 51 can also be configured as devices that can emit sound or light prompts. When the tray 5 is correctly inserted into the tray receiving chamber 34, the first fool-proofing structure 341 or the second fool-proofing structure 51 can emit light of a certain color or emit a specific sound to indicate correct operation and improve the operator's perception during operation.

[0092] In one embodiment, as shown in FIG9 , the tray body 52 may further include an operating portion 521 and a powder receiving portion 522. An operator can insert the tray 5 into the tray receiving chamber 34 by grasping or holding the operating portion 521. When the tray 5 is inserted into the tray receiving chamber 34 through the opening of the tray receiving chamber 34, the operating portion 521 protrudes from the tray receiving chamber 34 to facilitate operation by the operator. Of course, the operating portion 521 may be omitted, and the operator may simply grasp the tray body 52.

[0093] In one embodiment, the powder receiving portion 522 can be configured as a recessed groove away from the operating portion 521 to collect excess powder. Furthermore, the recessed groove is provided on the upper end surface of the tray body 52. ​​When the tray 5 is inserted into the tray receiving chamber 34, the powder receiving portion 522 faces the feed opening 32. After the operator inserts the powder measuring rod to fill it with powder, when removing the powder measuring rod, due to the limited size of the first rod receiving chamber 331 and the rod, any powder exceeding the predetermined amount is scraped off the rod by the first rod receiving chamber 331 and then enters the powder receiving portion 522 of the tray 5 for reuse.

[0094] In order to achieve the filling of different powders into different powder measuring rods, the present application discloses a powder filling assembly in some embodiments. Please refer to Figure 10, which shows a schematic diagram of a powder filling assembly in one embodiment of the present application. As shown in Figure 10, the filling device assembly includes a first powder filling device 3 and a second powder filling device 4. The first powder filling device 3 matches the first powder measuring rod and is used to fill the first powder into the first powder measuring rod; the second powder filling device 4 matches the second powder measuring rod and is used to fill the second powder into the second powder measuring rod. For example, the first powder measuring rod and the second powder measuring rod can be respectively configured as the powder measuring rod described in any embodiment of Figures 1 to 6 and their related descriptions; the first powder filling device 3 and the second powder filling device 4 can be respectively configured as the powder filling device described in any embodiment of Figures 7 to 8 and their related descriptions. More specifically, when the first powder measuring rod is configured as the first powder measuring rod 1 as shown in Figure 5, the first powder filling device 3 is configured as the first powder filling device 3 as shown in Figure 7; when the second powder measuring rod is configured as the second powder measuring rod 2 as shown in Figure 5, the second powder filling device 4 is configured as the second powder filling device 4 as shown in Figure 10.

[0095] In order to enable the operator to distinguish which type of powder needs to be filled into the first powder filling device and the second powder filling device (it can also be understood as distinguishing the powder measuring rods adapted for the first powder filling device and the second powder filling device, respectively), in one embodiment, the identification structure of the first powder filling device 3 matches the identification structure of the first powder measuring rod, and the identification structure of the second powder filling device matches the identification structure of the second powder measuring rod. Specifically, in the embodiment where the identification structure is configured as a letter identification, as shown in Figures 10 and 5, when the letter identification 115 of the first powder measuring rod 1 is configured as the letter A, the letter identification 35 of the first powder filling device 3 is also configured as the letter A; when the letter identification 215 of the second powder measuring rod 2 is configured as the letter B, the letter identification 45 of the second powder filling device 4 is also configured as the letter B.

[0096] In one embodiment, the first positioning groove of the first powder filling device is configured to have a predetermined angle relative to the vertical direction of its feed opening, and the predetermined angle relative to the vertical direction of the second powder filling device is configured to be opposite to the predetermined angle relative to the vertical direction of the feed opening. In the examples shown in Figures 10 and 5, the first positioning groove 332 of the first powder filling device 3 has a predetermined angle of -60° relative to the vertical direction of the feed opening 32 to accommodate the first powder measuring rod 1; the positioning groove 432 of the second powder filling device 4 has a predetermined angle of 60° relative to the vertical direction of its feed opening 42 to accommodate the second powder measuring rod 2.

[0097] The operation of using the second powder filling device 4 to fill the second powder measuring rod 2 is the same as the operation of using the first powder filling device 3 to fill the first powder measuring rod 1. The following is a detailed description of the filling of the first powder as an example with reference to Figures 5 and 10:

[0098] When using the first powder filling device 3 to fill the first powder into the first powder measuring rod 1, the operator first holds the operating portion 521 of the tray 5 and embeds the second fool-proof structure 51 into the first fool-proof structure 341 located at the distal end of the first powder filling device 3 to complete the installation of the tray 5. At this time, the powder receiving portion 522 is inside the first powder filling device 3 and faces the feed port 32, while the operating portion protrudes from the tray receiving chamber 34; then, the operator holds the gripping portion 113 of the first powder measuring rod 1 and embeds the positioning portion on the first powder measuring rod 1 into the first positioning groove 332 located at the proximal end of the first powder filling device 3 , to complete the installation of the first powder measuring rod 1. At this time, the dosage groove 12 on the first powder measuring rod 1 is aligned with the feed port 32 on the first powder filling device 3; then, the operator fills the first powder into the feed port 32 and gently taps the first powder filling device 3, so that the first powder falls to the bottom of the dosage groove 12 and fills the dosage groove 12; thereafter, the operator holds the gripping portion 113 of the first powder measuring rod 1 and pulls the first powder measuring rod 1 out of the first accommodating chamber 33; finally, the operator holds the operating part of the tray 5 and pulls the tray 5 out of the first powder filling device 3 to recover the first powder in the powder receiving portion 522.

[0099] After the powder is filled into the powder measuring rod, the powder itself is extremely susceptible to environmental influences due to its light particle weight. For example, air flow can easily cause the powder to fly, resulting in powder loss and inaccurate powder dosage during analysis and testing. In addition, impurities in the air can enter the powder, causing powder contamination. In view of this, some embodiments provided in this application also disclose a transfer device suitable for storing or transferring powder measuring rods, such as the powder measuring rods described in any of the aforementioned embodiments. Furthermore, the transfer device provides a receiving cavity for receiving the powder measuring rod on the base, so that the receiving cavity can wrap around the dosage slot of the powder measuring rod, thereby preventing direct contact between the powder contained in the dosage slot and the air, thereby avoiding powder loss and contamination, and thus ensuring the accuracy of analysis and testing. In addition, the transfer device also locks the operating section of the powder measuring rod by providing a frame that can be in a locked state, so that the powder measuring rod can be stored on the base or transferred with the base without being accidentally pulled out or falling off, thereby enhancing the safety of storing or transferring the powder measuring rod.

[0100] Please refer to Figures 11 and 12. Figure 11 shows a schematic diagram of the structure of the transfer device in one embodiment of the present application, and Figure 12 shows a schematic diagram of the disassembled structure of the transfer device in one embodiment of the present application. Figure 11 illustrates the powder measuring rod 1 configured in the transfer device 6. As shown in Figures 11 and 12, the transfer device 6 includes a base 61 and a frame 62. The base 61 is provided with a receiving cavity 611, and the receiving cavity 611 is used to receive the powder measuring rod. When the powder measuring rod is inserted into the receiving cavity 611, its operating section 111 protrudes from the receiving cavity 611 for operation (as shown in Figure 11). It should be noted that in order to distinguish it from the receiving cavity in other subsequent devices or components, in the embodiment, the receiving cavity included in the transfer device is also referred to as the second receiving cavity.

[0101] As shown in Figures 11 and 12, the frame 62 is used to support the base 61 and is movable relative to the base 61 to lock the powder measuring rod. In the locked state, the operating section 111 of the powder measuring rod is inoperable, allowing the powder measuring rod to be stored on the base 61 or moved with the base 61. The frame 62 being movable relative to the base 61 means that the base 61 and the frame 62 can be moved relative to each other. This can be done by moving only the base 61, only the frame 62, or both the base 61 and the frame 62.

[0102] In the locked state, the operating section 111 of the powder measuring rod is inoperable, meaning that the operator cannot remove the powder measuring rod by operating the operating section 111. For example, the frame 62 may partially or completely block the operating section 111, making it difficult for the operator to operate the operating section 111. Alternatively, the frame 62 may obstruct the movement path of the operating section 111, preventing the operator from moving the operating section 111 even if the operator can access it. In other words, in the locked state, the operating section of the powder measuring rod can be accessed or inaccessible by the operator, as long as the powder measuring rod cannot be removed from the second accommodating chamber of the transfer device.

[0103] In one embodiment, as shown in Figure 12, the base 61 is configured as a generally rectangular parallelepiped structure. Furthermore, it can be slender to accommodate multiple second accommodating cavities. To prevent the operator from being bumped, in the example shown in Figure 12, the base has curved edges or inclined surfaces on its upper and left and right sides.

[0104] In one embodiment, the second accommodating chamber 611 is formed by extending inward from an opening on the front end surface of the base 61, and the powder measuring rod 1 is inserted into the base 61 through the opening. As shown in Figure 12, the second accommodating chamber 611 includes a rod receiving chamber 6111 and a positioning groove 6112. It should be noted that, in order to distinguish it from the rod receiving chamber included in the accommodating chamber of other devices or components, in this embodiment, the rod receiving chamber included in the second accommodating chamber is also referred to as the second rod receiving chamber. Similarly, the positioning groove further included in the second accommodating chamber in subsequent embodiments is also referred to as the second positioning groove, and the positioning groove further included in the second accommodating chamber will not be repeated in subsequent references.

[0105] The second rod receiving chamber 6111 is for inserting the powder measuring rod. The second positioning groove 6112 is provided on the circumference of the second rod receiving chamber 6111 and is used to cooperate with the positioning portion of the powder measuring rod to limit the insertion depth of the powder measuring rod.

[0106] In one embodiment, the second positioning groove 6112 is configured to have a predetermined angle relative to the vertical direction of the horizontal plane of the base 61. This predetermined angle is consistent with the predetermined angle of the positioning portion of the powder measuring rod relative to the vertical direction of the dose slot. That is, the predetermined angle of the second positioning groove 6112 relative to the vertical direction of the horizontal plane of the base 61 is configured to be -60° or 60°. It is understood that when the predetermined angle between the axis of the positioning portion of the powder measuring rod and the vertical direction of the dose slot is -60°, the predetermined angle between the axis of the second positioning groove 6112 of the transfer device 6 and the vertical direction of the horizontal plane of the base 61 is also -60°. When the predetermined angle between the axis of the positioning portion of the powder measuring rod and the vertical direction of the dose slot is 60°, the predetermined angle between the axis of the second positioning groove 6112 of the transfer device 6 and the vertical direction of the horizontal plane of the base 61 is also 60°, and the vertical direction of the dose slot is aligned with the vertical direction of the horizontal plane of the base 61. In this way, it is ensured that when the rod is inserted into the second accommodating cavity 611, the second positioning groove 6112 fits with the positioning portion to position the powder measuring rod.

[0107] In one embodiment, the depth of the second rod receiving chamber 6111 is less than the length of the powder measuring rod, so that when the rod is inserted, its operating section protrudes from the second rod receiving chamber 6111. To ensure that the operating section of the powder measuring rod protrudes from the second accommodating cavity 611 when the rod is inserted into the second accommodating cavity 611, the depth of the second positioning groove 6112 can be limited. In a preferred example, the depth of the second positioning groove 6112 is configured to be 14 mm.

[0108] Specifically, when inserting any powder measuring rod, the operator needs to use the grip on the powder measuring rod to align the positioning portion on the powder measuring rod with the second positioning groove on the transfer device and insert it to the deepest, thereby inserting the rod of the powder measuring rod into the second rod receiving chamber of the transfer device.

[0109] To store or transfer multiple first powder measuring rods, in one embodiment, as shown in Figures 11 and 12, the second accommodating chambers 611 can be configured as multiple juxtaposed chambers. In one implementation, the number of second accommodating chambers 611 is 6, 7, 8, 9, 10, 11, 12, 13, or 14; preferably, the number of second accommodating chambers 611 is 10.

[0110] Furthermore, to facilitate operator identification of the multiple second accommodating cavities, in one embodiment, as shown in Figures 11 and 12, the upper surface of the base 61 is provided with numerical markings. Specifically, from left to right, the ten second accommodating cavities 611 are marked with the numbers 1, 2, 3, 4, 5, 6, 7, 8, 9, and 10, respectively, on the upper surface directly above the base 61.

[0111] In order to indicate the type of transfer device, in one embodiment, an identification structure is configured on the base of the transfer device. The type of transfer device refers to different transfer devices. Furthermore, the identification structure on the base can distinguish the type of medicinal powder contained in the second receiving chamber. The identification structure includes but is not limited to a visual identification of color, number, letter, or any combination of the above identifications. The manner in which the identification structure is configured on the base includes but is not limited to pasting, engraving, labeling, laser engraving, and digital display screen. Furthermore, in order to facilitate observation by the operator, the identification structure can be configured in the middle position of the upper surface of the base.

[0112] In the embodiment where the marking structure is configured as a letter marking, when an operator needs to distinguish the type of powder measuring rod inserted, and further distinguish the type of powder contained in the second accommodating chamber, the operator can achieve this purpose by observing the letter, thereby avoiding confusion. For example, as shown in Figure 12, the letter marking A on the upper surface of the base 61 of the transfer device 6 can instruct the operator to insert the powder measuring rod with the letter A on its end surface, such as the first powder measuring rod, into the second accommodating chamber 611; and the letter marking B on the upper surface of the base 61 of the transfer device 6 can instruct the operator to insert the powder measuring rod with the letter B on its end surface, such as the second powder measuring rod, into the second accommodating chamber 611. In this way, the operator can distinguish the type of powder measuring rod inserted into the second accommodating chamber 611, and further distinguish between the first powder and the second powder.

[0113] As shown in Figure 12, the frame 62 further includes a support portion 621 and a blocking portion 622. The support portion 621 is provided with a movement channel 623. The base 61 is supported by the movement channel 623 and can move relative to the support portion 621 along the movement channel. The blocking portion 622 is fixed to the support portion 621. When the base 61 moves relative to the support portion 621 to the end of the movement channel 623, it is located in the operable path of the operating section of the powder measuring rod, thereby hindering operation of the operating section.

[0114] In one embodiment, the movement channel 623 is configured in an inverted L-shape, so that the base 61 can move laterally and longitudinally relative to the support portion 621 in accordance with the movement channel 623. The following describes the movement of the base 61 relative to the support portion 621 in accordance with the movement channel 623 in accordance with (a) to (c) of Figures 13 , taking the inverted L-shaped movement channel 623 as an example.

[0115] Please refer to Figure 13, which shows a schematic diagram of the process of the frame moving relative to the base to lock the powder measuring rods in one embodiment of the present application. The transfer device 6 is shown in Figure 13a in an initial state. The initial state means that the operator can manipulate the operating section 111 of the powder measuring rod 1 to move along its operable path. In other words, the operator can sequentially insert or remove the ten powder measuring rods shown in Figure 13a from the corresponding ten second accommodating cavities. Of course, the operator does not have to insert or remove the same number of powder measuring rods as the second accommodating cavities of the transfer device. Depending on the application scenario, the operator can insert or remove fewer or the same number of powder measuring rods as the second accommodating cavities of the transfer device.

[0116] As shown in Figures 13b and 13c , the base 61 and frame 62 of the transfer device 6 are capable of relative movement. Specifically, as shown in Figure 13b , an operator moves the frame 62 forward, causing the base 61 to move relative to the transverse structure starting point of the inverted L-shaped structure of the moving channel 623 (i.e., the vertical structure starting point of the inverted L-shaped structure). Then, as shown in Figure 13c , the operator moves the frame 62 upward, causing the base 61 to move relative to the vertical structure starting point of the inverted L-shaped structure to the vertical structure ending point. In other words, the base 61 undergoes relative displacement relative to the frame 62 in the front-to-back and up-to-down directions. At this point, the blocking portion 622 on the frame 62 follows the frame's movement and is positioned within the operable path of the operating section of the powder measuring rod, thereby obstructing the operator's operation of the operating section.

[0117] Furthermore, to ensure that the blocking portion 622 remains in a position that blocks the operable path, as shown in FIG13d , the transfer device 6 can be further fixed in a locked state, for example, by an operator manipulating the frame 62 to keep it in the locked state. The structure and process of fixing the transfer device 6 in the locked state will be described in detail later.

[0118] In other embodiments, the movable channel 623 may also be configured in other structural shapes. For example, the movable channel 623 may be configured as a vertical structure, so that the base 61 can move longitudinally relative to the support portion along the movable channel. In this case, the operator first inserts the powder measuring rod into the second accommodating cavity, then operates the frame to move it to the end within the vertical structure of the movable channel 623. This positions the blocking portion in the operable path of the operating section of the powder measuring rod, thereby hindering the operator's insertion or removal of the operating section.

[0119] In one embodiment, as shown in FIG12 , the support portion 621 includes a first support frame 6211 and a second support frame 6212 arranged opposite each other. A movable channel 623 is configured on the first support frame 6211 and the second support frame 6212. For example, two movable channels 623 may be configured, one on each of the two opposing side walls of the first support frame 6211 and the second support frame 6212. The base 61 is relatively movable across the first support frame 6211 and the second support frame 6212 via the connecting portion 6213. Specifically, one connecting portion 6213 may be connected to the base 61 by passing through the movable channel 623 on the first support frame 6211, and the other connecting portion 6213 may be connected to the base 61 by passing through the movable channel 623 on the second support frame 6212. In some examples, as shown in FIG12 , the first support frame 6211 and the second support frame 6212 may be configured as a convex plate-like structure. In some examples, the connecting portion 6213 can be, for example, a bolt or a screw, and corresponding screw holes are provided on the base 61. Specifically, the nut portion of the connecting portion 6213 is larger than the width of the movable channel. When the connecting portion is connected to the base, the connecting portion interacts with the screw holes on the base. Due to the size limitation of the nut portion, the base is positioned in the movable channel 623 between the first support frame 6211 and the second support frame 6212 and will not fall out of the movable channel.

[0120] In one embodiment, the support portion 621 further includes a reinforcement plate 6214, which is connected between the first support frame 6211 and the second support frame 6212 to increase the strength of the support portion 621. In the example shown in Figure 12, the reinforcement plate 6214 is disposed at the distal end of the transfer device 6. Its shape and size fully match the structural surface of the support portion, and its materials include, but are not limited to, composite materials, metal plates, and glass fiber reinforced polymers. The reinforcement plate 6214 is connected to the support portion 621 by bonding, bolts, screws, or other mechanical connection methods to ensure a secure and reliable fixation.

[0121] In one embodiment, the blocking portion 622 is configured as a flat plate structure that spans the first and second support frames 6211, 6212. It cooperates with the movement of the base 61 within the movable channel 623 to block the operating section of the powder measuring rod. In the examples shown in Figures 1 and 12, the blocking portion 622 is located at the proximal end of the transfer device 6. The blocking portion 622 can be connected to the first and second support frames 6211, 6212 by bonding, bolts, screws, or other mechanical means to ensure a secure and reliable fixation.

[0122] In one embodiment, the frame 62 further includes a grip 624, which an operator manipulates to move the frame 62 relative to the base 61. To provide the operator with sufficient operating space, the grip 624 is positioned at the top of the frame 62, connecting the top ends of the first and second support frames, and is spaced a certain distance from the installation location of the base 61. The grip 624 can be connected to the first and second support frames 6211, 6212 by methods including, but not limited to, adhesive bonding, welding, and mortise and tenon joints.

[0123] In one embodiment, the frame 62 further includes a locking portion 625, which is used to lock the blocking portion 622 to maintain the operating section of the powder measuring rod in the operable path. In the example shown in Figure 12, the grip portion 624 is rotatably connected to the support portion 621, and the locking portion 625 is fixed to the grip portion 624. The operator locks the blocking portion 622 by rotating the grip portion 624. The locking portion 625 is configured as a plate-like structure fixed to the grip portion 624. Its length is slightly smaller than the distance between the upper surface of the base 61 and the grip portion 624 when the operating section of the powder measuring rod is locked.

[0124] Referring to Figure 13 , when the locking portion 625 is used to transition the powder measuring rod from its initial state (as shown in Figure 13a) to the locked state (as shown in Figure 13d), the operator manipulates the grip 624 of the transfer device 6 to move the frame 62 forward, causing the base 61 to move laterally relative to the connecting portion 6213 on the movable channel 623 to the state shown in Figure 13b. Next, the operator manipulates the grip 624 to pull the frame upward relative to the base 61 and rotates the grip 624 clockwise so that the locking portion 625 connected to the grip 624 is positioned vertically above the base 61. At this point, the base 61 moves longitudinally relative to the connecting portion 6213 on the movable channel 623 to the state shown in Figure 13c. Finally, the operator manipulates the grip 624 to lower the frame (or simply releases the grip 624 to allow the frame to fall under its own weight). At this point, the locking portion 625 contacts the upper surface of the base 61, resulting in the locked state shown in Figure 13d.

[0125] In another embodiment, the locking portion 625 is used to unlock the blocking portion 622 and move it off the operable path of the operating section of the powder measuring rod. In the example shown in Figure 12, the gripping portion 624 is rotatably connected to the support portion 621, and the locking portion 625 is fixed to the gripping portion 624. The operator unlocks the blocking portion 622 by rotating the gripping portion 624. Referring to Figure 13, when the operator needs to remove the powder measuring rod from the transfer device for testing, the locking portion 625 needs to be used to transform the powder measuring rod from the locked state shown in Figure 13d to the initial state shown in Figure 13a. Specifically, the operator needs to rotate the gripping portion 624 counterclockwise to unlock the blocking portion 622, and lower the frame 62 so that the blocking portion 622 of the transfer device 6 moves off the operable path of the operating section, forming the state shown in Figure 13b. Then, the operator operates the gripping portion 624 to move the frame 62 backward relative to the base 61 to form the state shown in FIG. 13 a . At this time, the operator can take out the powder measuring rod.

[0126] The following, in conjunction with Figure 13, details the operations required to store or transfer the powder measuring rods using the transfer device 6. The operator uses the grip on the powder measuring rod to align the positioning portion on the powder measuring rod with the second positioning groove 6112 on the transfer device 6 and insert it to its deepest position, thereby inserting the rod of the powder measuring rod into the second rod receiving chamber 6111 of the transfer device 6. The operator completes the insertion of each powder measuring rod in this manner and connects the base 61 to the connecting portion 6213 on the frame 62, forming the initial state shown in Figure 13a. Next, the operator operates the grip 624 of the transfer device 6 to move the frame 62 forward relative to the base 61. 13b ; thereafter, the operator operates the gripping portion 624 to pull the frame 62 upward relative to the base 61, and rotates the gripping portion 624 clockwise so that the locking portion 625 fixedly connected to the gripping portion 624 is vertically located above the base 61, forming the moving state as shown in FIG13c ; finally, the operator places the transfer device on a horizontal plane so that the locking portion 625 falls on the base 61, forming the locking state as shown in FIG13d to realize the storage or transfer of the powder measuring rod.

[0127] When the powder measuring rod needs to be taken out from the transfer device for analysis and testing, the unlocking steps of the powder measuring rod are opposite to the above-mentioned locking steps, which will not be described in detail here.

[0128] As mentioned above, when it is necessary to conduct an airflow analysis test on two powder mixtures, it is necessary to set up a powder measuring rod assembly, which includes a first powder measuring rod and a second powder measuring rod. In order to match this and realize the storage or transfer of the first powder measuring rod and the second powder measuring rod respectively, the present application discloses a transfer assembly in some embodiments, which includes a first transfer device and a second transfer device. The first transfer device is used to store or transfer the first powder measuring rod, and the second transfer device is used to store or transfer the second powder measuring rod. For example, the first powder measuring rod and the second powder measuring rod can be respectively configured as the powder measuring rods described in any embodiment of Figures 1 to 6 and their related descriptions; the first transfer device and the second transfer device can be respectively configured as the transfer devices described in any embodiment of Figures 11 to 13 and their related descriptions.

[0129] To enable operators to distinguish which powder measuring rods are contained in the first and second transfer devices, and thus which powders are being stored or transferred, in one embodiment, the identification structure of the first transfer device matches the identification structure of the first measuring rod, and the identification structure of the second transfer device matches the identification structure of the second measuring rod. Specifically, in an embodiment where the identification structure is configured as a letter identifier, when the letter identifier of the first powder measuring rod is A, the letter identifier of the first transfer device is also A; when the letter identifier of the second powder measuring rod is B, the letter identifier of the second transfer device is also B. Thus, operators can distinguish the first and second powders in the transfer devices based on the letters A and B.

[0130] In one embodiment, the preset angle of the positioning groove of the first transfer device relative to the vertical direction of the horizontal plane is configured to be opposite to the preset angle of the positioning groove of the second transfer device relative to the vertical direction of the horizontal plane. For example, when the preset angle of the positioning groove of the first transfer device relative to the vertical direction of the horizontal plane is -60 degrees, the corresponding preset angle of the axis direction of the positioning portion of the first powder measuring rod relative to the vertical direction of the dosage groove is also -60 degrees; when the preset angle of the positioning groove of the second transfer device relative to the vertical direction of the horizontal plane is 60 degrees, the corresponding preset angle of the axis direction of the positioning portion of the second powder measuring rod relative to the vertical direction of the dosage groove is also 60 degrees.

[0131] In order to cooperate with the powder measuring rod to distribute the powder and form an airflow, for example, to perform an airflow analysis test on the preset amount of powder contained in the dose slot in the powder measuring rod described in any of the aforementioned embodiments, the present application also discloses a simulated inhalation device in some embodiments, which realizes the distribution and guidance of the airflow by arranging a manifold on the main body; by arranging a accommodating cavity on the main body, the powder measuring rod can be placed in the accommodating cavity and the dose slot can be connected to the chamber inlet of the manifold, thereby forming an airflow carrying the powder.

[0132] Refer to Figure 14, which is a structural diagram of a simulated inhalation device in one embodiment of the present application. As shown in the figure, the simulated inhalation device 8 comprises a main body 81 and an accommodating chamber 82. A manifold (not shown in Figure 14) is configured on the main body 81, and the manifold is used to shunt airflow and guide the airflow direction. The accommodating chamber 82 is configured on the main body 81 to receive the powder measuring rod. The accommodating chamber 82 is communicated with the manifold so that the dose groove of the powder measuring rod is communicated with the manifold when the powder measuring rod docks the accommodating chamber, thereby allowing the airflow to carry the powder in the dose groove and be distributed through the manifold. It should be noted that in order to distinguish it from the accommodating chamber in other devices or components, in an embodiment, the accommodating chamber included in the simulated inhalation device is also referred to as the third accommodating chamber.

[0133] In one embodiment, as shown in Figure 14 , the main body 81 is configured as a substantially rectangular box-shaped structure. To prevent the operator from being bumped, in the example shown in Figure 14 , the edges of the main body 81 facing in all directions are configured as curved edges or inclined surface edges.

[0134] Please refer to Figure 15 , in conjunction with Figure 14 , which shows a cross-sectional schematic diagram of a manifold disposed within a main body according to one embodiment of the present application. As shown in Figures 15 and 14 , the main body 81 is provided with a distribution cavity 83, within which the manifold 9 is disposed. The distribution cavity 83 can be configured as a recessed groove located in the central region of the main body 81, with an opening toward the top surface of the main body 81 and an opening toward the side of the main body 81. The cavity's shape is adapted to accommodate the manifold, allowing it to enter.

[0135] In one embodiment, the distribution chamber 83 has an air inlet for the air flow to enter the manifold 9. For example, the air inlet can be an opening of the distribution chamber 83 toward the side of the main body 81. A positioning mechanism 84 is provided on the air inlet to keep the manifold 9 in the distribution chamber. The positioning mechanism 84 is provided on the end face of one side of the main body 81 and is provided with an air inlet structure corresponding to the air inlet so that the air flow can enter the air inlet. In the example shown in Figure 14, the air inlet structure is configured as a grid 841 provided on the positioning mechanism 84. On the one hand, the grid structure helps to achieve uniform airflow distribution, thereby avoiding the formation of an uneven flow field near the air inlet, ensuring that each area can receive a relatively uniform airflow. On the other hand, it helps to prevent pollutants in the air from entering the simulated inhalation device and being tested with the airflow, thereby ensuring the accuracy of the test results. In another example, the air inlet structure can be configured as a perforated plate structure provided on the positioning mechanism, that is, a plurality of evenly distributed small holes are provided on the positioning mechanism so that a uniform airflow is generated when the airflow passes through the perforated plate structure.

[0136] In one embodiment, as shown in FIG14 , the positioning mechanism 84 includes a positioning plate 842 and a fixing mechanism 843. The positioning plate 842 is removably secured to the air inlet by the fixing mechanism 843. It should be understood that when the positioning plate 842 is secured to the air inlet, it can securely secure the manifold mounted within the main body 81. When the positioning plate 842 is removed from the air inlet, the manifold can be removed from the main body 81 for post-test cleaning.

[0137] In one implementation, as shown in FIG14 , the positioning plate 842 is provided with a first engaging portion 8421, the fixing mechanism 843 is connected to the main body 81 and is provided with a second engaging portion 8431, and the fixing mechanism 843 is rotated to engage or release the second engaging portion 8431 with the first engaging portion 8421. It should be understood that the engagement may refer to a state in which the second engaging portion 8431 and the first engaging portion 8421 are locked to each other and cannot move relative to each other, and the release may refer to a state in which the second engaging portion 8431 releases the lock on the first engaging portion 8421, allowing it to be removed from the main body.

[0138] The fixing mechanism includes at least one fixing member, which is configured as an eccentric bolt screwed onto the main body 81. In this case, the second coupling portion 8431 is configured as the head of the eccentric bolt. The eccentric bolt includes a head and a rod. In one embodiment, the rod is arranged at a position offset from the center of the head; in another embodiment, the head is configured as a quasi-circular shape including a straight edge, and the rod is connected to the main body 81. Specifically, as shown in Figure 14, the first coupling portion 8421 is configured as a groove located on both sides of the positioning plate 842. The groove cooperates with the head of the eccentric bolt to complete the installation and removal of the positioning plate 842 at the air inlet. Specifically, when the straight edge of the eccentric bolt head is rotated to the groove position of the first coupling portion and is parallel to the groove, the positioning plate 842 can be removed from the air inlet; when the straight edge of the eccentric bolt head is away from the groove position of the first coupling portion, the positioning plate 842 is fixed to the main body of the simulated inhalation device.

[0139] Refer to Figure 14 to Figure 17, wherein, Figure 16 is shown as the fixed mechanism of the application's simulated inhalation device in one embodiment and the schematic diagram that positioning plate releases mutually, and Figure 17 is shown as the fixed mechanism of the application's simulated inhalation device in one embodiment and the schematic diagram that positioning plate engages mutually.After completing the installation of manifold 9 in distribution chamber 83, simulated inhalation device is transformed into the state shown in Figure 15 by the state of Figure 14, subsequently, the operating personnel need to install positioning plate 842 shown in Figure 14 to block described air inlet, with the straight edge of eccentric bolt head along vertical direction towards the 3rd accommodating chamber, at this moment, positioning plate 842 is installed to the position of air inlet, form state as shown in Figure 16; Then the operating personnel manipulates described eccentric bolt, until the straight edge of its head is away from the groove position on positioning plate, form state as shown in Figure 17.When positioning plate 842 was disassembled after completing the test operation, the operating personnel only needed to manipulate eccentric bolt, make the straight edge of its head again along vertical direction towards distribution chamber, to form state as shown in Figure 16.

[0140] In one embodiment, the manifold can direct the direction of the airflow, pulverizing the powdered drug into uniform particles while carried by the airflow, thereby improving the accuracy of airflow analysis testing. In another embodiment, the manifold can divide the airflow into multiple branches, allowing the airflow in each branch to flow in multiple different specific directions, ensuring uniform distribution of the airflow within the testing area and thus improving the reliability of the test results.

[0141] Continuing to refer to FIG. 15 in conjunction with FIG. 14 , the manifold 9 includes a chamber 91 having a chamber inlet 911 and a chamber outlet 912. In this case, the airflow can, for example, enter the chamber inlet 911 of the manifold 9 through the air inlet on the distribution chamber 83, and then be directed from the chamber inlet 911 to the chamber outlet 912. Furthermore, the manifold 9 also includes an airway (not shown), the airway having an airway outlet and an airway inlet connected to the chamber inlet 911. In this case, the airflow can first enter the airway inlet of the manifold 9 through the air inlet on the distribution chamber 83, and then enter the chamber inlet 911 through the airway outlet and be directed to the chamber outlet 912.

[0142] In one embodiment, the third accommodating chamber 82 is in communication with the distribution chamber 83. When the manifold 9 is disposed in the distribution chamber 83, the third accommodating chamber 82 is in communication with the manifold 9. Referring to FIG18 , a cross-sectional view of the simulated inhalation device of one embodiment of the present application without the manifold installed is shown. As shown in FIG18 , the third accommodating chamber 82 and the distribution chamber 83 are both formed in the main body 81 and are in communication with each other via a through-port 85. When the manifold 9 is disposed in the distribution chamber 83, the chamber entrance faces the through-port 85.

[0143] Please continue to refer to Figure 15 in conjunction with Figure 14. As shown in Figures 14 and 15, when the powder measuring rod is inserted into the third accommodating chamber 82, the dosage groove of the powder measuring rod faces the through-port 85 and is opposite to the chamber entrance, so that the airflow entering from the air duct entrance enters the dosage groove through the air duct outlet, carries the powder to the chamber entrance, and is then directed to the chamber outlet.

[0144] In one embodiment, described chamber entrance and described airway outlet are arranged side by side to produce an airflow channel.When the rod of powder measuring rod is docked with described simulated inhalation device, the opening of described dose groove is towards described airflow channel, so that airflow passes through described dose groove to described chamber entrance from described airway outlet, and is then directed to chamber outlet by described chamber entrance, to complete test operation.When carrying out airflow analysis test, simulated inhalation device is by being connected with an interface to simulate suction, produces negative pressure in manifold, makes air enter simulated inhalation device from air inlet, is inhaled from the airway entrance of manifold again, and passes through the airway outlet of manifold, because the opening of the dose groove of described powder measuring rod is towards airway outlet and chamber entrance, air enters in the dose groove at the airway outlet and carries powder, forms airflow with uniform powder particles, and enters the chamber entrance of manifold, leaves from the chamber outlet of manifold subsequently.

[0145] In one embodiment, the third accommodating chamber is used to receive a powder measuring rod. Please refer to FIG19 , which is a schematic structural diagram of a simulated inhalation device in one embodiment of the present application from another perspective. As shown in FIG19 , the third accommodating chamber includes a rod receiving chamber 821 for inserting the rod of the powder measuring rod. In one example, the rod receiving chamber 821 is configured as a hole structure that passes through the main body 81 from front to back. When the positioning plate 842 shown in FIG14 is installed on the main body 81, it can close the rear part of the hole structure, which has a positioning effect on the powder measuring rod to a certain extent. It should be noted that in order to distinguish it from the rod receiving chamber included in the accommodating chamber in other devices or components, in the embodiment, the rod receiving chamber included in the third accommodating chamber is also referred to as the third rod receiving chamber, and no further details will be given when the rod receiving chamber further included in the third accommodating chamber is mentioned later.

[0146] In one embodiment, the third rod receiving chamber 821 is sized to fit snugly around the rod, so that when inserted into the third accommodating cavity 82, the third rod receiving chamber 821 seals the dosage slot, thereby preventing external air, impurities, or moisture from interfering with the powder. This helps maintain a consistent testing environment, thereby reducing the impact of interfering factors on test results.

[0147] In one embodiment, as shown in Figure 19, the third accommodating chamber, in addition to including a third rod receiving chamber 821, may further include a groove structure 822 formed in the circumference of the third rod receiving chamber 821. The groove structure 822 is used to cooperate with the positioning portion of the powder measuring rod so that the powder measuring rod can dock with the third accommodating chamber 82 in accordance with the movement trajectory of the groove structure 822.

[0148] In one embodiment, please refer to FIG. 20 in conjunction with FIG. 19 , wherein FIG. 20 is a cross-sectional view of a simulated inhalation device according to one embodiment of the present application. As shown in FIG. 19 and FIG. 20 , the groove structure 822 includes a first groove 8221 and a second groove 8222. The first groove 8221 is formed by axially extending on the inner wall of the third accommodating chamber 82, that is, extending in the longitudinal direction of the third accommodating chamber 82; the second groove 8222 is connected to the first groove 8221 and is configured to be formed by continuing the first groove 8221 to extend in the circumferential direction of the third accommodating chamber 82, that is, the second groove 8222 extends in the circumferential direction of the third accommodating chamber 82 and is connected to the first groove 8221. The powder measuring rod is operated so that the positioning portion is converted from axial movement in the first groove 8221 to circumferential rotation in the second groove 8222 to complete the docking. Specifically, during the docking process, the operator manipulates the operating section of the powder measuring rod to insert the rod into the third rod receiving chamber 821. During this insertion, the positioning portion of the powder measuring rod moves linearly within the first slot 8221. To align the opening of the dosage slot on the powder measuring rod toward the airway outlet and the chamber inlet, the operator manipulates the operating section to rotate the rod. During this process, the positioning portion of the powder measuring rod rotates within the second slot 8222.

[0149] In one embodiment, the third accommodating chamber 82 can be configured as two to accommodate two powder measuring rods. The airflow carries and mixes the powder in the dosage slots of the two powder measuring rods, directing it from the chamber inlet to the chamber outlet. In one implementation, the two third accommodating chambers are arranged in a mirror-symmetrical manner on either side of the manifold, connecting to their corresponding chamber inlets. For ease of distinction, the two third accommodating chambers are referred to as third accommodating chamber a and third accommodating chamber b, respectively; the two powder measuring rods are referred to as powder measuring rod a and powder measuring rod b, respectively. As shown in Figure 20, the main body 81 is configured with two mirror-symmetrical third accommodating chambers, namely, third accommodating chamber a and third accommodating chamber b. Third accommodating chamber a is used to receive powder measuring rod a, while third accommodating chamber b is used to receive powder measuring rod b. When the manifold 9 is installed in the distribution chamber, it is located exactly midway between the third accommodating chambers a and b. When conducting an airflow analysis test, the airflow is evenly divided into two airflows as it flows from the airway inlet of the manifold to the airway outlet. These two airflows carry the powder in the dosage groove on the powder measuring rod a and the powder in the dosage groove on the powder measuring rod b respectively, and then enter the chamber inlet of the manifold at the same time for mixing. The mixed airflow is then guided to the chamber outlet through the chamber inlet.

[0150] To facilitate operator differentiation between the two third accommodating chambers, in one embodiment, identification structures are provided around the perimeter of the third accommodating chambers to indicate the types of the two powder measuring rods received by the two third accommodating chambers, thereby indicating the types of powder contained within the dosage slots of the two powder measuring rods. The identification structures include, but are not limited to, visual identification such as color, number, or letter, or any combination thereof. Methods for disposing the identification structures around the third accommodating chambers include, but are not limited to, stickers, engravings, labels, laser markings, and digital displays. Furthermore, to facilitate operator observation, the identification structures may be disposed on the proximal end surface of the main body, directly above a third accommodating chamber corresponding to a particular powder measuring rod.

[0151] In embodiments where the identification structure is configured as a letter identifier, the letter corresponding to the letter identifier can be used to indicate the type of powder measuring rod received. When different types of powders are used for analysis and testing, or when powders from different powder measuring rods need to be mixed during analysis and testing, the letter identifier can provide a convenient visual indication to the operator. By observing the letter identifier, the operator can determine the type of powder measuring rod received and, therefore, the type of powder contained in the powder measuring rod, thereby avoiding confusion. For example, a letter identifier A on the proximal end surface of the main body can indicate that a first powder measuring rod is received and a predetermined amount of the first powder is contained in the dose slot. If a letter identifier B on the proximal end surface of the main body indicates that a second powder measuring rod is received and a predetermined amount of the second powder is contained in the dose slot, the letter identifiers A and B can be arranged side by side.

[0152] When the third accommodating chamber can be configured as two mirror-symmetrical chambers for docking with two powder measuring rods, taking the example of inserting the first powder measuring rod into the third accommodating chamber a and the second powder measuring rod into the third accommodating chamber b, the first and second powder measuring rods can be configured as the powder measuring rods described in any of the embodiments shown in Figures 1 to 6 and their related descriptions, for example, the first and second powder measuring rods 1 and 2 shown in Figure 5. Please refer to Figure 21 in conjunction with Figure 20, which shows a schematic diagram of the docking process of the simulated inhalation device and the powder measuring rods in one embodiment of the present application. As shown in Figure 21, the operator inserts the first powder measuring rod 1 into its corresponding third accommodating cavity using the letter markings. During insertion, the operator manipulates the operating section of the first powder measuring rod 1 to align its positioning portion with the slot structure of the third accommodating cavity marked with letter A, thereby inserting the first powder measuring rod 1 into the third accommodating cavity marked with letter A, resulting in the state shown in Figure 21a. At this time, the opening direction of the dosage slot of the first powder measuring rod 1 is vertical, and the letter marking A on the proximal end surface is at a preset angle of 45° to the vertical direction of the dosage slot. The operator then manipulates the operating section of the first powder measuring rod 1 to rotate the first powder measuring rod 1 counterclockwise by 45° (as indicated by the arrow in Figure 21b). At this time, the letter marking A on the proximal end surface of the first powder measuring rod 1 is vertical, completing the docking of the first powder measuring rod 1, resulting in the state shown in Figure 21b. At this time, the dosage slot of the first powder measuring rod 1 is oriented toward the airway outlet of the manifold and the chamber inlet.

[0153] After docking the first powder measuring rod 1, the operator next needs to dock the second powder measuring rod 2. In the example shown in Figure 5, the second powder measuring rod 2 is longer than the first powder measuring rod 1. Therefore, when completing the docking operation as shown in Figure 21, the operator can avoid conflict with the first powder measuring rod 1. Continuing with Figure 21, the operator inserts the second powder measuring rod 2 into its corresponding third accommodating cavity using the letter mark. During insertion, the operator first manipulates the operating section of the second powder measuring rod 2 to align the positioning portion of the second powder measuring rod with the groove structure of the third accommodating cavity marked with letter B, thereby inserting the second powder measuring rod 2 into the third accommodating cavity marked with letter B, resulting in the state shown in Figure 21c. At this time, the dosage slot of the second powder measuring rod 2 is opened vertically, and the angle between the letter mark B on the proximal end face and the vertical direction of the dosage slot is preset to -45°. Then, the operator holds the operating section of the second powder measuring rod 2 to rotate the second powder measuring rod 2 clockwise by 45° (as indicated by the arrow in Figure 21d) until the letter mark B on the proximal end face of the second powder measuring rod 2 is in a vertical direction to complete the docking of the second powder measuring rod 2, forming the state shown in Figure 21d. At this time, the dosage groove of the second powder measuring rod 2 is facing the air duct outlet and the chamber inlet of the manifold.

[0154] After the docking of the first powder measuring rod 1 and the second powder measuring rod 2 is completed, the operator connects the simulated inhalation device to an interface to simulate the inhalation process, thereby generating negative pressure in the simulated inhalation device, so that air enters from the air inlet, is sucked into the air duct inlet of the manifold, and passes through the air duct outlet of the manifold, carrying the first powder and the second powder in the dosage slot of the first powder measuring rod 1 and the dosage slot of the second powder measuring rod 2 respectively, mixes the first powder and the second powder to form an airflow with uniform powder particles, and then enters the chamber inlet of the manifold, and finally leaves from the chamber outlet of the manifold.

[0155] The following describes the operation of performing analysis and testing using the simulated inhalation device in conjunction with Figures 14 to 21:

[0156] First, the operator rotates the fixing mechanism 843 to release the first coupling portion, thereby removing the positioning plate 842 from the main body 81; then, the manifold 9 is inserted into the distribution chamber 83. At this time, the manifold 9 is located in the middle position of the two third accommodating chambers; after completing the installation of the manifold 9, the operator rotates the fixing mechanism 843 to make the first coupling portion and the second coupling portion in a locked state, thereby realizing the installation of the positioning plate 842 on the main body 81; then, the operator manipulates the operating section of the first powder measuring rod to insert the rod along the first groove 8221 into the third accommodating chamber marked with the letter A, and then rotates the first powder measuring rod along the second groove 8222 so that its dosage groove faces the air duct outlet and chamber inlet of the manifold; thereafter, the operator manipulates the operating section of the second powder measuring rod to insert the rod along the first groove 8221 into the third accommodating chamber marked with the letter B, and then rotates the second powder measuring rod along the second groove 8222 so that its dosage groove faces the air duct outlet and chamber inlet of the manifold, ready for subsequent testing operations.

[0157] In some embodiments, the drug powder measurement system disclosed herein may further include a testing device and an access device. The testing device is configured to correspond to the chamber outlet of the simulated inhalation device to complete the testing operation. For example, when the particle uniformity of the drug powder needs to be tested, the testing device can be configured as a dosage unit sampling device; when the particle size classification of the drug powder needs to be performed, the measuring device can be configured as a new generation pharmaceutical impactor.

[0158] The access device is used to configure the simulated inhalation device so as to transfer the simulated inhalation device to correspond to the test device. In one example, the access device is provided with a pin, and in conjunction with the pin, the left and right side surfaces of the main body of the simulated inhalation device are provided with holes that can cooperate with the pin on the access device, thereby allowing the simulated inhalation device to be installed on the access device. Furthermore, the installation height of the access device and the simulated inhalation device is the same as the height of the test device, so that the chamber entrance of the simulated inhalation device can correspond to the test device, thereby generating airflow to complete the corresponding airflow analysis test.

[0159] It should be noted that the above-mentioned powder measuring system is merely an example. In some embodiments, the powder measuring system disclosed in the present application may also include a combination of any of the above-mentioned rods, components, devices, or equipment. For example, the powder measuring system may include a powder measuring rod, a simulated inhalation device, a testing device, and an access device. For the powder measuring rod, please refer to the contents of any embodiment of Figures 1 to 6 and the related descriptions thereof; for the simulated inhalation device, please refer to the contents of any embodiment of Figures 14 to 21 and the related descriptions thereof, which will not be repeated here; for the testing device and the access device, please refer to the previous descriptions, which will not be repeated here.

[0160] In summary, the powder measuring system disclosed in the present application, by providing a powder measuring rod, realizes the accommodation of a preset amount of powder, thereby achieving the accuracy of the test dose; by providing a powder filling device, realizes the filling of a preset amount of powder in the powder measuring rod, thereby further achieving the accuracy of the test; by providing a transfer device, the storage and transfer of the powder measuring rod are realized, which can avoid the loss and contamination of the powder; by providing a simulated inhalation device, the formation of airflow can be realized, and the docking with the powder measuring rod can be completed for drug distribution; through the synergistic effect of the powder measuring rod, the powder filling device, the transfer device and the simulated inhalation device, the airflow analysis test of the airflow distribution device such as the inhaler can be realized, thereby avoiding the consumable test of the inhaler itself.

[0161] Based on the description of the above examples, this application provides multiple embodiments, which are as follows:

[0162] 1. A powder filling device for filling powder into a powder measuring rod, the powder filling device comprising a body and a feed port; the body is provided with a receiving cavity for receiving the powder measuring rod; the feed port is arranged on the body and is connected to the receiving cavity, and when the powder measuring rod is placed in the receiving cavity, the dosage groove arranged thereon faces the feed port so that the powder falls into the dosage groove through the feed port.

[0163] 2. According to the powder filling device described in Example 1, the main body includes a base and a filling part supported on the base, the accommodating cavity is formed on the filling part in a front-to-rear through-going manner, and the feed port extends in a vertical direction at the top of the filling part to be connected with the accommodating cavity.

[0164] 3. According to the powder filling device of embodiment 1 or 2, the feed port is configured as a hole structure with a cross-section that continuously decreases from top to bottom.

[0165] 4. According to the medicine powder filling device of embodiment 1, the accommodating chamber includes a rod receiving chamber for inserting the rod of the medicine powder measuring rod.

[0166] 5. According to the powder filling device of embodiment 4, the depth of the rod receiving chamber is smaller than the length of the rod, so that when the rod is inserted, the operating section thereof protrudes from the rod receiving chamber.

[0167] 6. According to the powder filling device of embodiment 4, the rod receiving chamber has a size that fits snugly with the rod, so that when the rod is taken out, the rod receiving chamber blocks more than a preset amount of powder from being taken out by the rod.

[0168] 7. According to the powder filling device described in Example 4, the accommodating chamber also includes a positioning groove formed in the circumference of the rod receiving chamber, and the positioning groove is used to cooperate with the positioning part of the powder measuring rod so that when the positioning part is inserted into the end of the positioning groove, the dosage groove of the powder measuring rod is aligned with the feed port.

[0169] 8. According to the powder filling device of embodiment 7, the positioning groove is configured to have a preset angle compared to the vertical direction of the feed port, and the preset angle is consistent with the preset angle of the positioning portion compared to the vertical direction of the dosage groove.

[0170] 9. According to the powder filling device of embodiment 7, the positioning groove has a preset angle of -60° or 60° compared to the vertical direction of the feed port.

[0171] 10. According to the medicine powder filling device of embodiment 7, the depth of the positioning groove is configured to be 10 mm.

[0172] 11. According to the medicine powder filling device of embodiment 1, an identification structure is configured on the body to indicate the type of the medicine powder filling device.

[0173] 12. According to the medicine powder filling device of embodiment 11, the identification structure is configured as a letter identification, and the letters corresponding to the letter identification are used to indicate the type of the medicine powder filling device.

[0174] 13. The powder filling device according to embodiment 11, wherein the identification structure is configured to be formed on an end surface of the proximal end of the body.

[0175] 14. The powder filling device according to embodiment 1 further comprises a tray receiving chamber arranged relative to the feed port and communicating with the accommodating cavity, wherein the tray receiving chamber is used for inserting a tray to receive excess powder.

[0176] 15. According to the powder filling device described in Example 14, the tray receiving chamber includes a first fool-proofing structure, and the tray includes a second fool-proofing structure adapted to the first fool-proofing structure, and the first fool-proofing structure is combined with the second fool-proofing structure when the tray is inserted into the tray receiving chamber.

[0177] 16. According to the powder filling device of embodiment 15, the second fool-proofing structure is configured as a protrusion structure at the bottom of the tray body.

[0178] 17. The powder filling device according to embodiment 14, wherein the tray receiving chamber is formed by an opening on the end surface of the distal end of the body extending inwardly, and the tray is inserted into the tray receiving chamber through the opening.

[0179] 18. According to the medicine powder filling device of embodiment 14, the main body of the tray includes an operating portion, and when the tray is inserted into the tray receiving chamber, the operating portion protrudes from the tray receiving chamber for operation.

[0180] 19. According to the powder filling device of embodiment 1, the powder measuring rod is used to connect to a simulated inhalation device to complete a testing operation.

[0181] 20. According to the powder filling device described in Example 19, the powder measuring rod includes a rod and a dosage groove formed on the circumferential surface of the rod. When docked, the dosage groove is connected to the chamber inlet of the simulated inhalation device so that the airflow carries the powder in the dosage groove from the chamber inlet to the chamber outlet of the simulated inhalation device.

[0182] 21. A powder filling assembly, comprising a first powder filling device and a second powder filling device; the first powder filling device is used to fill the first powder into a first powder measuring rod; the second powder filling device is used to fill the second powder into a second powder measuring rod; wherein, the first powder filling device or the second powder filling device is configured as a powder filling device as described in any one of embodiments 1 to 20.

[0183] 22. The drug powder filling assembly according to embodiment 21, wherein the first drug powder is configured to contain a bronchodilator as an active pharmaceutical ingredient, and the second drug powder is configured to contain an anti-inflammatory drug as an active pharmaceutical ingredient.

[0184] 23. According to the powder filling assembly of embodiment 21, the identification structure of the first powder filling device matches the identification structure of the first measuring rod, and the identification structure of the second powder filling device matches the identification structure of the second measuring rod.

[0185] 24. The powder filling assembly according to embodiment 21, wherein the letter identification of the first powder filling device is configured as the letter A, and the letter identification of the second powder filling device is configured as the letter B.

[0186] 25. According to the powder filling assembly of embodiment 21, the preset angle of the positioning groove of the first powder filling device compared to the vertical direction of its feed port is configured to be in opposite directions to the preset angle of the positioning groove of the second powder filling device compared to the vertical direction of its feed port.

[0187] 26. A powder measuring system, comprising a powder measuring rod, a powder filling device, a transfer device, and a simulated inhalation device; the powder measuring rod is used to accommodate a preset amount of powder; the powder filling device is used to receive the powder measuring rod to fill the powder into the powder measuring rod, and is configured as a powder filling device as described in any one of embodiments 1 to 20; the transfer device is used to receive the powder measuring rod containing powder to store or transfer the powder measuring rod; the simulated inhalation device is used to receive the powder measuring rod to dock with the powder measuring rod, and during docking, the airflow carries the powder in the dosage slot of the powder measuring rod from the chamber inlet to the chamber outlet of the simulated inhalation device to complete the test operation.

[0188] 27. A simulated inhalation device for dispensing powder in cooperation with a powder measuring rod, the simulated inhalation device comprising a main body and a accommodating chamber; a manifold is arranged on the main body, the manifold having a chamber inlet and a chamber outlet; the accommodating chamber is arranged on the main body to receive the powder measuring rod, which is connected to the chamber inlet so that when the powder measuring rod is docked with the accommodating chamber, the dosage groove of the powder measuring rod is connected to the chamber inlet, so that the airflow can carry the powder in the dosage groove from the chamber inlet to the chamber outlet.

[0189] 28. According to the simulated inhalation device of embodiment 27, a distribution chamber for configuring the manifold is provided on the main body, and the distribution chamber has an air inlet connected to the chamber inlet for allowing the airflow to enter the manifold.

[0190] 29. According to the simulated inhalation device described in Example 28, a positioning mechanism is provided on the air inlet to maintain the manifold in the distribution chamber, and an air intake structure corresponding to the air inlet is provided on the positioning mechanism so that the air flow can enter the air inlet.

[0191] 30. According to the simulated inhalation device of embodiment 29, the air intake structure is configured as a grid opened on the positioning mechanism.

[0192] 31. According to the simulated inhalation device of embodiment 29, the positioning mechanism includes a positioning plate, and the positioning plate is detachably covered on the air inlet through a fixing mechanism.

[0193] 32. According to the simulated inhalation device of embodiment 31, a first coupling portion is provided on the positioning plate, the fixing mechanism is connected to the main body and is configured with a second coupling portion, and the fixing mechanism is rotated to engage or release the second coupling portion with the first coupling portion.

[0194] 33. According to the simulated inhalation device of embodiment 32, the fixing mechanism includes at least one fixing member, the fixing member is configured as an eccentric bolt screwed on the main body, and the head of the eccentric bolt is configured as the second coupling portion.

[0195] 34. According to the simulated inhalation device of embodiment 28, the distribution chamber and the accommodating chamber are connected through a through-port, and when the manifold is arranged in the distribution chamber, the chamber inlet faces the through-port.

[0196] 35. According to the simulated inhalation device of embodiment 34, when the powder measuring rod is docked with the accommodating chamber, the dosage groove faces the through-port and is opposite to the chamber entrance.

[0197] 36. The simulated inhalation device according to embodiment 1, wherein the accommodating chamber comprises a rod receiving chamber for inserting a rod of the powder measuring rod.

[0198] 37. The simulated inhalation device of embodiment 36, wherein the rod receiving chamber has dimensions that snugly fit the rod such that the rod receiving chamber closes the dose slot when inserted into the receiving cavity.

[0199] 38. According to the simulated inhalation device described in Example 36, the accommodating chamber also includes a groove structure formed around the rod receiving chamber, and the groove structure is used to cooperate with the positioning portion of the powder measuring rod so that the powder measuring rod can dock with the accommodating chamber in a manner that conforms to the movement trajectory of the groove structure.

[0200] 39. According to the simulated inhalation device described in Example 38, the groove structure includes a first groove and a second groove; the first groove is formed by axially extending on the inner wall of the accommodating cavity; the second groove is connected to the first groove and is configured to be formed by continuing to extend the first groove in the circumferential direction of the accommodating cavity; wherein the powder measuring rod is operated so that the positioning part is converted from axial movement in the first groove to circumferential rotation in the second groove to complete the docking.

[0201] 40. The simulated inhalation device according to embodiment 27, wherein the accommodating chamber is configured to be two to receive two powder measuring rods, and the airflow carries and mixes the powder in the dosage grooves of the two powder measuring rods and is guided from the chamber inlet to the chamber outlet.

[0202] 41. According to the simulated inhalation device of embodiment 27, the two accommodating chambers are arranged on both sides of the manifold in a mirror-symmetrical manner to respectively connect to their corresponding chamber inlets.

[0203] 42. According to the simulated inhalation device of embodiment 27, an identification structure is provided around the accommodating chamber to indicate the type of powder measuring rod that the accommodating chamber is used to receive.

[0204] 43. The simulated inhalation device according to embodiment 42, wherein the identification structure is configured as an alphabetical identification, and the letters corresponding to the alphabetical identification are used to indicate the type of the received powder measuring rod.

[0205] 44. According to the simulated inhalation device of embodiment 43, there are two accommodating chambers, the letter corresponding to the letter identification of the first accommodating chamber is the letter A, and the letter corresponding to the letter identification of the second accommodating chamber is the letter B.

[0206] 45. According to the simulated inhalation device described in Example 27, the manifold includes a chamber and an airway; the chamber has the chamber inlet and the chamber outlet; the airway has an airway outlet and an airway inlet connected to the chamber inlet, and when the powder measuring rod is docked with the accommodating chamber, the opening of the dose groove faces the airway outlet and the chamber inlet, so that the airflow entering from the airway inlet enters the dose groove through the airway outlet and carries the powder to the chamber inlet.

[0207] 46. ​​The simulated inhalation device according to embodiment 45, wherein the chamber inlet and the airway outlet are arranged side by side.

[0208] 47. A powder measuring system, comprising a powder measuring rod, a simulated inhalation device, a testing device, and an access device; the powder measuring rod is used to accommodate a preset amount of powder; the simulated inhalation device is used to dock with the powder measuring rod to distribute powder, and is configured as a simulated inhalation device as described in any one of Examples 27 to 46; the testing device is used to correspond to the chamber outlet of the simulated inhalation device to complete a testing operation; the access device is used to configure the simulated inhalation device to transfer the simulated inhalation device to correspond to the test device.

[0209] 48. A powder measuring system, comprising a powder measuring rod, a powder filling device, a transfer device, and a simulated inhalation device; the powder measuring rod is used to accommodate a preset amount of powder; the powder filling device is used to receive the powder measuring rod to fill the powder into the powder measuring rod; the transfer device is used to receive the powder measuring rod containing powder to store or transfer the powder measuring rod; the simulated inhalation device is used to dock with the powder measuring rod to distribute powder, and is configured as a simulated inhalation device as described in any one of Examples 27 to 46.

[0210] 49. The powder measuring system according to Example 48 further includes a testing device and an access device; the testing device is used to correspond to the chamber outlet of the simulated inhalation device to complete the testing operation; the access device is used to configure the simulated inhalation device to transfer the simulated inhalation device to correspond to the testing device.

[0211] 50. A transfer device suitable for storing or transferring powder measuring rods, the transfer device comprising a base and a frame; the base is provided with a accommodating cavity for receiving the powder measuring rod, and when the powder measuring rod is inserted into the accommodating cavity, its operating section protrudes from the accommodating cavity for operation; the frame is used to support the base, and it can be moved relative to the base to lock the powder measuring rod, and the operating section of the powder measuring rod is inoperable in the locked state, so that the powder measuring rod can be stored on the base or transferred following the base.

[0212] 51. According to the transfer device described in Example 50, the accommodating cavity is formed by an opening on the end surface of the front end of the base extending inward, and the powder measuring rod is inserted into the base through the opening.

[0213] 52. According to the transfer device of embodiment 50, the accommodating chamber includes a rod receiving chamber, and the rod of the powder measuring rod is inserted into the rod receiving chamber.

[0214] 53. According to the transfer device described in embodiment 52, the depth of the rod receiving chamber is smaller than the length of the rod, so that when the rod is inserted, its operating section protrudes from the rod receiving chamber.

[0215] 54. According to the transfer device described in embodiment 52, the accommodating cavity also includes a positioning groove formed in the circumference of the rod receiving chamber, and the positioning groove is used to cooperate with the positioning portion of the powder measuring rod to limit the insertion depth of the powder measuring rod.

[0216] 55. According to the transfer device described in Example 54, the positioning groove is configured to have a preset angle compared to the vertical direction of the horizontal plane where the base is located, and the preset angle is consistent with the preset angle of the positioning portion compared to the vertical direction of the dosage groove of the powder measuring rod.

[0217] 56. According to the transfer device described in Example 55, the preset angle configuration of the positioning groove compared to the vertical direction of the horizontal plane where the base is located is -60° or 60°.

[0218] 57. According to the transfer device described in Example 54, the depth of the positioning groove is configured to be 14 mm.

[0219] 58. According to the transfer device described in Example 50, the accommodating chamber can be configured as a plurality of accommodating chambers arranged in parallel.

[0220] 59. According to the transfer device described in Example 50, the number of the accommodating cavities is 6 to 14.

[0221] 60. According to the transfer device described in Example 50, the number of the accommodating cavities is 10.

[0222] 61. According to the transfer device described in Example 50, an identification structure is configured on the base to indicate the type of the transfer device.

[0223] 62. According to the transfer device described in Example 61, the identification structure is configured as a letter identification, and the letters corresponding to the letter identification are used to indicate the type of the transfer device.

[0224] 63. According to the transfer device described in Example 50, the frame includes a supporting part and a blocking part; a movable channel is provided on the supporting part, the base is supported on the movable channel and can move relative to the supporting part in accordance with the movable channel; the blocking part is fixedly provided on the supporting part, and when the base moves to the terminal end of the movable channel relative to the supporting part, it is located on the operable path of the operating section to hinder the operation of the operating section.

[0225] 64. According to the transfer device described in Example 63, the supporting part includes a first supporting frame and a second supporting frame which are arranged opposite to each other and are respectively provided with the movable channels, and are respectively connected to the base through a connecting part passing through the movable channels corresponding to each supporting frame so that the base can move relatively across the two supporting frames.

[0226] 65. According to the transfer device described in Example 64, the support part also includes a reinforcing plate connected to the first support frame and the second support frame, which is used to increase the strength of the support part.

[0227] 66. According to the transfer device described in embodiment 64, the blocking part is configured as a flat plate structure spanning the first support frame and the second support frame.

[0228] 67. According to the transfer device described in Example 63, the moving channel is configured as an inverted L-shape so that the base can move laterally and vertically relative to the support part in accordance with the moving channel.

[0229] 68. According to the transfer device described in Example 63, the frame also includes a gripping portion connected to the support portion, and the frame is moved relative to the base by operating the gripping portion.

[0230] 69. According to the transfer device according to embodiment 63 or 68, the frame further includes a locking portion for locking or unlocking the blocking portion so that the blocking portion remains on or leaves the operable path of the operating section.

[0231] 70. According to the transfer device described in Example 69, the holding portion is rotatably connected to the supporting portion, and the locking portion is fixed on the holding portion, and the blocking portion is locked or unlocked by rotating the holding portion.

[0232] 71. A transfer assembly, comprising a first transfer device and a second transfer device: the first transfer device is used to store or transfer a first powder measuring rod; the second transfer device is used to store or transfer a second powder measuring rod; wherein the first transfer device or the second transfer device is configured as a transfer device as described in any one of embodiments 50 to 70.

[0233] 72. According to the transfer assembly of embodiment 71, the first powder contained in the first powder measuring rod is configured to contain a bronchodilator as an active pharmaceutical ingredient, and the second powder contained in the second powder measuring rod is configured to contain an anti-inflammatory drug as an active pharmaceutical ingredient.

[0234] 73. According to the transfer assembly of embodiment 71, the identification structure of the first transfer device matches the identification structure of the first measuring rod, and the identification structure of the second transfer device matches the identification structure of the second measuring rod.

[0235] 74. According to the transfer component of embodiment 71, the letter identification of the first transfer device is configured as letter A, and the letter identification of the second transfer device is configured as letter B.

[0236] 75. According to the transfer assembly described in Example 71, the preset angle of the positioning groove of the first transfer device compared to the vertical direction of the horizontal plane and the preset angle of the positioning groove of the second transfer device compared to the vertical direction of the horizontal plane are configured to be in opposite directions.

[0237] 76. A powder measuring system, comprising a powder measuring rod, a powder filling device, a transfer device, and a simulated inhalation device; the powder measuring rod is used to accommodate a preset amount of powder; the powder filling device is used to receive the powder measuring rod to fill the powder into the powder measuring rod; the transfer device is used to receive the powder measuring rod containing powder to store or transfer the powder measuring rod, and is configured as a transfer device as described in any one of Examples 50 to 70; the simulated inhalation device is used to receive the powder measuring rod to dock with the powder measuring rod, and during docking, the airflow carries the powder in the dosage slot of the powder measuring rod from the chamber inlet to the chamber outlet of the simulated inhalation device to complete the test operation.

[0238] The above embodiments are merely illustrative of the invention and the beneficial effects achieved by this application and are not intended to limit this application. Anyone familiar with the art may modify or alter the above embodiments without departing from the principles and scope of this application. Therefore, all equivalent modifications or alterations accomplished by a person of ordinary skill in the art without departing from the spirit and technical concepts disclosed in this application shall be covered by the claims of this application.

Claims

1. A powder measuring rod, characterized in that: The powder measuring rod comprises: A rod comprising a rod body, an operating section located at a proximal end of the rod body, and a measuring section located at a distal end of the rod body; A dose groove is formed on the circumference of the measuring section and is used to accommodate a preset amount of powder. When the rod is transferred to a simulated inhalation device through the operating section, the dose groove is connected to the chamber inlet of the simulated inhalation device so that airflow carrying the powder in the dose groove is guided from the chamber inlet to the chamber outlet of the simulated inhalation device to complete the test operation.

2. The powder measuring rod according to claim 1, characterized in that: The operating section is provided with a gripping portion for operating the rod.

3. The powder measuring rod according to claim 2, characterized in that: The gripping portion is configured as a recessed structure formed on the circumference of the operating section, and the recessed structure provides a holding space.

4. The powder measuring rod according to claim 3, characterized in that: The recessed structure includes a first recessed portion and a second recessed portion, and the first recessed portion and the second recessed portion are relatively distributed on the circumference of the operating section for finger gripping.

5. The powder measuring rod according to claim 1, characterized in that: The dose groove is configured to have a nearly oval opening.

6. The powder measuring rod according to claim 1, characterized in that: The dosage groove is configured as a groove structure with a cross section that decreases continuously from top to bottom.

7. The powder measuring rod according to claim 1, characterized in that: The preset amount is configured as any value not greater than 30 μl, and the dosage groove has a holding volume corresponding to the preset amount.

8. The powder measuring rod according to claim 1, characterized in that: The rod is provided with an identification structure for indicating the type of the powder measuring rod and / or the status of the powder measuring rod.

9. The powder measuring rod according to claim 8, characterized in that: The identification structure is configured as a letter identification, the letters corresponding to the letter identification are used to indicate the type of the powder measuring rod, and the posture of the letters corresponding to the letter identification is used to indicate the state of the powder measuring rod.

10. The powder measuring rod according to claim 8, characterized in that: When the rod is docked with the simulated inhalation device, the marking structure rotates from a vertical direction with a preset angle to a horizontal plane to an upright position to indicate correct docking.

11. The powder measuring rod according to claim 8 or 10, characterized in that: The identification structure is configured to have a preset angle relative to a vertical direction of the dosage slot.

12. The powder measuring rod according to claim 11, characterized in that: The preset angle is configured to be -45° or 45°.

13. The powder measuring rod according to claim 1, characterized in that: The rod has a preset length, and the preset length is used to indicate the type of the powder measuring rod.

14. The powder measuring rod according to claim 1, characterized in that: The invention also includes a positioning portion configured on the bottom side of the rod, which is used to support the rod so that the opening of the dosage groove faces upward when the rod is placed on a horizontal surface.

15. The powder measuring rod according to claim 14, characterized in that: The positioning portion is configured to have a predetermined angle relative to a vertical direction of the dose slot.

16. The powder measuring rod according to claim 15, characterized in that: The preset angle is configured as -60° or 60°.

17. The powder measuring rod according to claim 14, characterized in that: The positioning portion is configured as a cylindrical structure or a convex point structure protruding in the circumferential direction of the rod.

18. The powder measuring rod according to claim 1, characterized in that: The pharmaceutical powder is formulated to contain a bronchodilator as an active pharmaceutical ingredient or is formulated to contain an anti-inflammatory drug as an active pharmaceutical ingredient.

19. The powder measuring rod according to claim 1, characterized in that: The simulated inhalation apparatus comprises a manifold comprising: a chamber having the chamber inlet and the chamber outlet; The airway has an airway outlet communicating with the chamber inlet, and when the rod is docked with the simulated inhalation device, the opening of the dose groove faces the airway outlet and the chamber inlet, so that airflow is passed from the airway outlet through the dose groove to the chamber inlet.

20. A powder measuring rod assembly, characterized in that: include: The first powder measuring rod and the second powder measuring rod are respectively used to accommodate a preset amount of first powder and a preset amount of second powder to cooperate with a simulated inhalation device to complete a test operation; Wherein, each powder measuring rod is configured as a powder measuring rod as described in any one of claims 1 to 19.

21. The powder measuring rod assembly according to claim 20, characterized in that: The first powder measuring rod contains a first powder configured to contain a bronchodilator as an active pharmaceutical ingredient, and the second powder measuring rod contains a second powder configured to contain an anti-inflammatory drug as an active pharmaceutical ingredient.

22. The powder measuring rod assembly according to claim 20, characterized in that: The letter identification of the first powder measuring rod is configured as letter A, and the letter identification of the second powder measuring rod is configured as letter B.

23. The powder measuring rod assembly according to claim 20, characterized in that: The preset angle between the marking structure of the first powder measuring rod and the vertical direction of its dosage slot is opposite to the preset angle between the marking structure of the second powder measuring rod and the vertical direction of its dosage slot.

24. The powder measuring rod assembly according to claim 20, wherein: The first medicine powder measuring rod and the second medicine powder measuring rod have different preset lengths.

25. The powder measuring rod assembly according to claim 24, characterized in that: The preset length of the second medicine powder measuring rod is longer than that of the first medicine powder measuring rod.

26. The powder measuring rod assembly according to claim 24, characterized in that: The preset length difference between the second powder measuring rod and the first powder measuring rod is any value between 16 mm and 20 mm.

27. The powder measuring rod assembly according to claim 20, characterized in that: The preset angle of the positioning portion of the first powder measuring rod relative to the vertical direction of the dosage slot thereof is configured to be opposite to the preset angle of the positioning portion of the second powder measuring rod relative to the vertical direction of the dosage slot thereof.

28. A medicine powder measuring system, characterized in that: include: A powder measuring rod, which is configured as the powder measuring rod according to any one of claims 1 to 19; a medicine powder filling device, which is used to receive the medicine powder measuring rod to fill the medicine powder into the medicine powder measuring rod; a transfer device for receiving a powder measuring rod containing powder to store or transfer the powder measuring rod; The simulated inhalation device is used to receive the powder measuring rod and dock with the powder measuring rod. During docking, the airflow carries the powder in the dosage slot of the powder measuring rod from the chamber inlet to the chamber outlet of the simulated inhalation device to complete the test operation.

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