Sample analyzer

Abstract

Provided is a sample analyzer, comprising a first consumable supply device, a second consumable supply device, a sample storage device, a sample dispensing device, a nucleic acid extraction device, an amplification device, a test device, a first scheduling device, and a pipetting device. The first scheduling device comprises a first consumable conveying assembly and a second consumable conveying assembly, wherein the first consumable conveying assembly and the second consumable conveying assembly are arranged side by side, a second side of the first consumable conveying assembly is adjacent to a first side of the second consumable conveying assembly, at least one of the sample storage device, the nucleic acid extraction device and the amplification device is at least partially located on a first side of the first consumable conveying assembly, and at least another one of the sample storage device, the nucleic acid extraction device and the amplification device is at least partially located on a second side of the second consumable conveying assembly. A consumable scheduling network of the sample analyzer is simplified, thereby reducing the footprint and cost of the sample analyzer.

Description

Sample analyzer

[0001] CROSS-REFERENCE TO RELATED APPLICATIONS

[0002] This application is based on and claims the priority of Chinese patent application with application number 2024103855378 and application date March 29, 2024. The entire content of the Chinese patent application is hereby incorporated into this application by reference. Technical Field

[0003] The present invention relates to the field of in vitro diagnostic equipment, and in particular to a sample analyzer. Background Art

[0004] Related technology provides a sample analyzer that tests samples using molecular diagnostic technology. Molecular diagnostic technology uses DNA and RNA as diagnostic materials and molecular biology techniques to diagnose human conditions and diseases by detecting the presence, defects, or abnormal expression of genes. Its basic principle is to detect changes in the structure, quantity, and expression function of DNA or RNA to determine whether the subject has abnormal genetic changes. This is of great significance for the prevention, prediction, diagnosis, treatment, and prognosis of diseases. Because molecular diagnosis requires multiple steps such as sample preparation, nucleic acid extraction, and reaction system setup, the corresponding sample analyzer has numerous functional modules. In addition, to ensure a complete sample input and result output, numerous auxiliary functional modules such as reagent management, waste management, and contamination prevention are also required. A sample analyzer integrating so many functional modules can be extremely large if its layout is not well designed. Molecular laboratories used to house these sample analyzers require isolation and a negative pressure laboratory environment to prevent contamination. Therefore, the overall area of ​​current molecular laboratories is generally small. Placing a bulky sample analyzer in a relatively small molecular laboratory will cause great trouble to users.

[0005] In the sample analyzers provided by related technologies, the layout scheme adopted for each functional module is as follows: the consumables supply device, sample storage device, reagent storage device, nucleic acid extraction device, and amplification device and other functional modules are arranged in a straight line along a single horizontal direction. This results in the sample analyzer being very large in a single horizontal direction, resulting in very low space utilization in the molecular laboratory, which is likely to cause user dissatisfaction. In addition, the related technology uses multiple manipulators to dispatch consumables such as nucleic acid extraction containers and amplification reaction vessels between the various functional modules. To avoid interference, the multiple manipulators are staggered, which makes the consumables dispatching network of the sample analyzer relatively chaotic and complex, thereby affecting the dispatching efficiency of nucleic acid extraction containers and amplification reaction vessels between the various functional modules. Summary of the Invention

[0006] The first object of the present invention is to provide a sample analyzer, which aims to solve the technical problem of a complex consumables scheduling network in a sample analyzer with nucleic acid extraction and amplification detection functions in the related art.

[0007] To achieve the above object, the present invention provides the following solutions:

[0008] A sample analyzer includes a first consumables supply device, a second consumables supply device, a sample storage device, a sample distribution device, a nucleic acid extraction device, an amplification device, a detection device, a first scheduling device, and a pipetting device; wherein:

[0009] The first consumables supply device is at least used to provide a nucleic acid extraction container;

[0010] The second consumables supply device is at least used to provide an amplification reaction container;

[0011] The first scheduling device includes a first consumable conveying assembly and a second consumable conveying assembly, the first consumable conveying assembly is at least used to carry the nucleic acid extraction container for linear movement along a first horizontal direction, the second consumable conveying assembly is at least used to carry the amplification reaction container for linear movement along the first horizontal direction, the first consumable conveying assembly and the second consumable conveying assembly are arranged side by side along a second horizontal direction, the second horizontal direction is approximately perpendicular to the first horizontal direction, the first consumable conveying assembly has a first side and a second side arranged on opposite sides along the second horizontal direction, the second consumable conveying assembly has a first side and a second side arranged on opposite sides along the second horizontal direction, the second side of the first consumable conveying assembly is adjacent to the first side of the second consumable conveying assembly, at least a portion of at least one of the sample storage device, the nucleic acid extraction device and the amplification device is located on the first side of the first consumable conveying assembly, and at least a portion of at least the other of the sample storage device, the nucleic acid extraction device and the amplification device is located on the second side of the second consumable conveying assembly;

[0012] The sample storage device is at least used to store a sample container loaded with a sample;

[0013] The sample distributing device is used to draw at least part of the sample from the sample container provided by the sample storage device and dispense it into the nucleic acid extraction container provided by the first consumables supply device;

[0014] The nucleic acid extraction device is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container to obtain a nucleic acid extraction solution;

[0015] The pipetting device is used to draw at least part of the nucleic acid extraction solution from the nucleic acid extraction container and dispense it into the amplification reaction container provided by the second consumables supply device;

[0016] The amplification device is used to amplify the liquid in the amplification reaction container containing at least the nucleic acid extract to obtain a liquid to be tested;

[0017] The detection device is used to detect the liquid to be tested.

[0018] In one embodiment, the first consumable material transport assembly includes a first guide rail, a first movable seat, and a first driving mechanism, wherein the first guide rail extends along the first horizontal direction, the first movable seat can be movably connected to the first guide rail to carry the nucleic acid extraction container to move linearly along the first guide rail, and the first driving mechanism is used to drive the first movable seat to move linearly along the first guide rail;

[0019] The second consumable material transport assembly includes a second guide rail, a second movable seat, and a second driving mechanism, wherein the second guide rail extends along the first horizontal direction, the second movable seat is at least used to carry the amplification reaction container to perform linear motion along the second guide rail, and the second driving mechanism is used to drive the second movable seat to perform linear motion along the second guide rail;

[0020] Wherein, the first guide rail and the second guide rail are arranged side by side along the second horizontal direction.

[0021] As an embodiment, a first receiving groove for placing the nucleic acid extraction container is provided on the top of the first movable seat, and the sample analyzer further comprises a second scheduling device and a third scheduling device, the second scheduling device being used to place the nucleic acid extraction container provided by the first consumable supply device into the first receiving groove from above the first movable seat, and the third scheduling device being used to take out the nucleic acid extraction container at least loaded with a sample placed in the first receiving groove from above the first movable seat and dispatch it to the nucleic acid extraction device; and / or,

[0022] A second receiving groove for placing the amplification reaction container is provided on the top of the second movable seat. The sample analyzer also includes a fourth scheduling device and a fifth scheduling device. The fourth scheduling device is used to place the amplification reaction container provided by the second consumable supply device from above the second movable seat into the second receiving groove. The fifth scheduling device is used to take out the amplification reaction container placed in the second receiving groove and loaded with at least the nucleic acid extract from above the second movable seat and schedule it to the amplification device.

[0023] As an embodiment, the second movable seat is further used to carry the nucleic acid extraction container to perform linear motion along the second guide rail; and / or,

[0024] The top of the second movable seat is also provided with a third receiving groove for placing the nucleic acid extraction container. The sample analyzer also includes a third scheduling device. The third scheduling device is used to schedule the nucleic acid extraction container loaded with the nucleic acid extraction liquid from the nucleic acid extraction device to the top of the second movable seat and place the nucleic acid extraction container from the top of the second movable seat into the third receiving groove, and to take out the nucleic acid extraction container placed in the third receiving groove from the top of the second movable seat and schedule it to the recovery position for recovery.

[0025] As an embodiment, the first consumable material transport assembly includes a first guide rail, which extends along the first horizontal direction. The sample analyzer also includes a reagent storage device and a reagent dispensing device, wherein the reagent storage device is used to store reagents, and the reagent dispensing device is used to dispense the reagents provided by the reagent storage device into the nucleic acid extraction container and / or the amplification reaction container. The orthographic projection of any one of the reagent storage device, the sample storage device, the nucleic acid extraction device and the amplification device on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the first guide rail on the vertical plane; and / or,

[0026] The second consumable material transport assembly includes a second guide rail, which extends along the first horizontal direction. The sample analyzer also includes a reagent storage device and a reagent dispensing device. The reagent storage device is used to store reagents, and the reagent dispensing device is used to dispense the reagents provided by the reagent storage device into the nucleic acid extraction container and / or the amplification reaction container. The orthographic projection of any one of the reagent storage device, the sample storage device, the nucleic acid extraction device and the amplification device on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the second guide rail on the vertical plane.

[0027] As an embodiment, the sample storage device is located on a first side of the first consumable material transport assembly, and at least a portion of at least one of the nucleic acid extraction device and the amplification device is located on a second side of the second consumable material transport assembly; or,

[0028] The sample storage device is located on the second side of the second consumable material transport assembly, and at least a portion of at least one of the nucleic acid extraction device and the amplification device is located on the first side of the first consumable material transport assembly.

[0029] As an embodiment, the sample storage device is located on the first side of the first consumable material transport assembly, the nucleic acid extraction device and the amplification device are at least partially located on the second side of the second consumable material transport assembly, and the nucleic acid extraction device and the amplification device are arranged side by side along the first horizontal direction.

[0030] As an embodiment, the sample analyzer further comprises a reagent storage device and a reagent dispensing device, wherein the reagent storage device is used to store reagents, and the reagent dispensing device is used to dispense the reagents provided by the reagent storage device into the nucleic acid extraction container and / or the amplification reaction container;

[0031] The reagent storage device and the sample storage device are distributed side by side along the first horizontal direction on a first side of the first consumable material conveying assembly.

[0032] As an embodiment, the reagent storage device includes a first reagent storage component and a second reagent storage component, and the reagent dispensing device includes a first reagent dispensing component and a second reagent dispensing component;

[0033] The first reagent storage component is used to store a first type of reagent, the first reagent dispensing component is used to draw the first type of reagent from the first reagent storage component and dispense it into the nucleic acid extraction container, and the nucleic acid extraction device is used to extract nucleic acid from the liquid in the nucleic acid extraction container containing at least the sample and the first type of reagent to obtain the nucleic acid extraction solution;

[0034] The second reagent storage assembly is used to store a second type of reagent, the second reagent dispensing assembly is used to draw the second type of reagent from the second reagent storage assembly and dispense it into the amplification reaction container, and the amplification device is used to amplify the liquid in the amplification reaction container containing at least the nucleic acid extract and the second type of reagent to obtain the test liquid;

[0035] At least part of the second consumable material supply device, the first reagent storage assembly, the second reagent storage assembly, and the sample storage device are distributed side by side in the first consumable material conveying assembly along the first horizontal direction.

[0036] As an embodiment, the distance from the sample storage device to the nucleic acid extraction device is shorter than the distance to the amplification device.

[0037] As an embodiment, the first reagent dispensing assembly and the second reagent dispensing assembly are the same reagent dispensing assembly, and the same reagent dispensing assembly includes a reagent needle, a first lifting mechanism, and a first horizontal moving mechanism;

[0038] The reagent needle is used to draw the first type of reagent from the first reagent storage component and inject it into the nucleic acid extraction container, and is used to draw the second type of reagent from the second reagent storage component and inject it into the amplification reaction container;

[0039] The output end of the first lifting mechanism is connected to the reagent needle to drive the reagent needle to move up and down;

[0040] The output end of the first horizontal moving mechanism is connected to the first lifting mechanism to drive the first lifting mechanism to drive the reagent needle to move horizontally;

[0041] The sample analyzer also includes a fourth scheduling device, which is used to transfer the amplification reaction container from the second consumable supply device to the second consumable conveying assembly. The fourth scheduling device includes a first clamping device and a second lifting mechanism. The first clamping device is used to clamp and release the amplification reaction container. The output end of the second lifting mechanism is connected to the first clamping device to at least drive the first clamping device to move up and down. The output end of the first horizontal moving mechanism is also connected to the second lifting mechanism to drive the second lifting mechanism to drive the first clamping device to move horizontally.

[0042] In one embodiment, the first consumable transport assembly has a first reagent dispensing position, a sample adding position, and a first transfer position distributed along the first horizontal direction, and the first consumable transport assembly is at least used to carry the nucleic acid extraction container and move it to the first reagent dispensing position, the sample adding position, and the first transfer position in sequence;

[0043] The first reagent dispensing component is used to draw at least part of the first type of reagent from the first reagent storage component and inject it into the nucleic acid extraction container located at the first reagent injection position;

[0044] The sample distributing device is used to draw at least part of the sample from the sample container and dispense it into the nucleic acid extraction container located at the sample loading position;

[0045] The sample analyzer further includes a third scheduling device, which is used to schedule the nucleic acid extraction container located at the first transfer position and loaded with the sample and the first type of reagent to the nucleic acid extraction device.

[0046] As an embodiment, the first type of reagents includes magnetic bead reagents, lysis reagents and elution reagents;

[0047] The nucleic acid extraction container is formed with a reaction hole and a first liquid storage hole, the reaction hole is used to carry a liquid obtained by mixing at least a sample with a magnetic bead reagent, a lysis reagent and an elution reagent for nucleic acid extraction, and the first liquid storage hole is used to store the elution reagent;

[0048] When the nucleic acid extraction container is located at the first reagent dispensing position, the first reagent dispensing component draws at least part of the magnetic bead reagent and the lysis reagent from the first reagent storage component and dispenses them into the reaction well, and draws at least part of the elution reagent from the first reagent storage component and dispenses it into the first liquid storage well;

[0049] The first consumable material transport assembly is used to carry the nucleic acid extraction container loaded with at least a magnetic bead reagent, a lysis reagent, and an elution reagent from the first reagent dispensing position to the sample adding position;

[0050] The third dispatching device is used to dispatch the nucleic acid extraction container located at the first transfer position and loaded with at least a sample and a magnetic bead reagent, a lysis reagent, and an elution reagent to the nucleic acid extraction device;

[0051] The nucleic acid extraction device is further used to draw at least part of the elution reagent from the first liquid storage hole and inject it into the reaction hole during the nucleic acid extraction process.

[0052] As an embodiment, the first reagent storage component is also used to store silicone oil;

[0053] The nucleic acid extraction container is further formed with a second liquid storage hole, and the second liquid storage hole is used to store silicone oil;

[0054] When the nucleic acid extraction container is located at the first reagent dispensing position, the first reagent dispensing assembly is further used to draw at least part of the silicone oil from the first reagent storage assembly and dispense it into the second liquid storage hole; the first consumables conveying assembly is used to carry the nucleic acid extraction container loaded with at least magnetic bead reagent, lysis reagent, elution reagent, and silicone oil from the first reagent dispensing position to the sample loading position;

[0055] The third dispatching device is used to dispatch the nucleic acid extraction container located at the first transfer position and loaded with at least a sample and a magnetic bead reagent, a lysis reagent, an elution reagent, and silicone oil to the nucleic acid extraction device;

[0056] The pipetting device is further used to draw at least a portion of the silicone oil from the second liquid storage hole and inject it into the amplification reaction container loaded with the nucleic acid extract.

[0057] In one embodiment, the second consumable material transport assembly has a second reagent dispensing position, a first liquid injection position, and a second transfer position distributed along the first horizontal direction, and the second consumable material transport assembly is at least used to carry the amplification reaction container from the second reagent dispensing position to the first liquid injection position and the second transfer position in sequence;

[0058] The second reagent dispensing assembly is used to draw at least part of the second type of reagent from the second reagent storage assembly and dispense it into the amplification reaction container located at the second reagent dispensing position;

[0059] The liquid transfer device is used to draw at least a portion of the nucleic acid extraction solution from the nucleic acid extraction container and inject it into the amplification reaction container located at the first injection position;

[0060] The sample analyzer further includes a fifth scheduling device, which is used to schedule the amplification reaction container located at the second transfer position and loaded with the nucleic acid extract and the second type of reagent to the amplification device.

[0061] As an embodiment, the second consumable material conveying assembly further has a third transfer position and a first liquid aspiration position distributed along the first horizontal direction;

[0062] The sample analyzer further includes a third dispatching device and a first magnetic attraction component, wherein the third dispatching device is used to dispatch the nucleic acid extraction container loaded with the nucleic acid extraction solution from the nucleic acid extraction device to the third transfer position;

[0063] The second consumable material transport assembly is further used to carry the nucleic acid extraction container loaded with the nucleic acid extraction solution and move it from the third transfer position to the first liquid aspiration position;

[0064] The first magnetic attraction component is disposed beside the first liquid aspiration position, and is used to perform magnetic attraction on the nucleic acid extraction liquid in the nucleic acid extraction container located at the first liquid aspiration position;

[0065] The pipetting device is used to draw at least a portion of the nucleic acid extraction solution from the nucleic acid extraction container located at the first liquid aspiration position and inject it into the amplification reaction container located at the first liquid injection position.

[0066] In one embodiment, the second consumable material transport assembly includes a second guide rail, a second movable seat, and a second driving mechanism, wherein the second guide rail extends along the first horizontal direction, a second receiving groove for placing the amplification reaction container and a third receiving groove for placing the nucleic acid extraction container are provided on the top of the second movable seat, and the second driving mechanism is used to drive the second movable seat to perform linear motion along the second guide rail;

[0067] The sample analyzer further includes a controller and a sixth scheduling device, wherein the controller is configured to perform the following control actions:

[0068] Controlling the sixth scheduling device to schedule the amplification reaction container provided by the second consumables supply device to the second reagent dispensing position and placing the amplification reaction container in the second containing slot of the second movable seat;

[0069] Controlling the second reagent dispensing assembly to draw at least a portion of the second type of reagent from the second reagent storage assembly and inject it into the amplification reaction container placed on the second movable seat and located at the second reagent injection position;

[0070] controlling the second driving mechanism to drive the second movable seat to perform linear motion along the second guide rail so that the second movable seat drives the amplification reaction container loaded with the second type of reagent to move, and moves the third receiving groove of the second movable seat to the third transfer position;

[0071] Controlling the third dispatching device to dispatch the nucleic acid extraction container loaded with the nucleic acid extraction solution from the nucleic acid extraction device to the third transfer position and place it in the third containing groove of the second movable seat;

[0072] controlling the second driving mechanism to drive the second movable seat to move the amplification reaction container loaded with the second type of reagent and the nucleic acid extraction container loaded with the nucleic acid extracting solution, so that the nucleic acid extraction container loaded with the nucleic acid extracting solution moves to the first liquid aspiration position, and the amplification reaction container loaded with the second type of reagent moves to the first liquid filling position;

[0073] Controlling the pipetting device to draw at least a portion of the nucleic acid extraction solution from the nucleic acid extraction container located at the first liquid aspiration position and dispensing the solution into the amplification reaction container located at the first liquid injection position;

[0074] Controlling the third dispatching device to remove the nucleic acid extraction container placed in the third containing tank and located at the first liquid aspiration position from above the second movable seat and dispatching it to a recovery position for discarding and recycling;

[0075] Controlling the second driving mechanism to drive the second movable seat to move so as to move the amplification reaction container loaded with the nucleic acid extract and the second type of reagent from the first liquid filling position to the second transfer position;

[0076] The fifth scheduling device is controlled to transfer the amplification reaction container located at the second transfer position and loaded with the nucleic acid extract and the second type of reagent to the amplification device.

[0077] As an embodiment, the first consumables supply device is provided below the second consumables supply device, and the first consumables supply device extends from below the second consumables supply device to below the reagent storage device; and / or,

[0078] The sample analyzer also includes a housing assembly, which is divided into a first chamber and a second chamber along the first horizontal direction. The second consumable supply device and the reagent storage device are distributed in the first chamber along the first horizontal direction, and the sample storage device is arranged in the second chamber; the reagent dispensing device includes a reagent needle, and the first chamber is provided with a first opening for the reagent needle to enter and exit; the sample dispensing device includes a sample needle, and the second chamber is provided with a second opening for the sample needle to enter and exit.

[0079] As an embodiment, the first consumable transport assembly is used to carry the nucleic acid extraction container for movement but is not used to carry the amplification reaction container for movement, and the second consumable transport assembly is used to carry the amplification reaction container for movement and can be used to carry the nucleic acid extraction container for movement; and / or,

[0080] The first consumables supply device is also used to store pipette tips; the nucleic acid extraction container is formed with a reaction well and at least one pipette tip hole, the reaction well is used to carry a liquid obtained by mixing at least the sample and the first type of reagent for nucleic acid extraction, and the pipette tip hole is used to accommodate the pipette tip; the pipetting device is used to draw at least part of the nucleic acid extraction liquid from the nucleic acid extraction container through the pipette tip and inject it into the amplification reaction container.

[0081] As an embodiment, the nucleic acid extraction device includes a first functional component, a second functional component and a scheduling component, the second functional component is arranged below or above the first functional component, the scheduling component is used to schedule the nucleic acid extraction container between the second functional component and the first functional component, the first functional component is at least used to carry the nucleic acid extraction container to perform a first functional action, the second functional component is at least used to carry the nucleic acid extraction container to perform a second functional action, the second functional action at least includes an incubation action, and the first functional action at least includes a magnetic adsorption action and a liquid aspiration action; and / or,

[0082] The nucleic acid extraction device has at least two workstations, each of which is used to carry the nucleic acid extraction container to perform a processing action. At least two of the workstations are distributed up and down in the vertical direction. The processing action includes at least one of incubation action, magnetic adsorption action, and liquid aspiration action.

[0083] A second object of the present invention is to provide a sample analyzer comprising a first consumables supply device, a second consumables supply device, a sample storage device, a sample distribution device, a nucleic acid extraction device, an amplification device, a detection device, a first scheduling device, and a pipetting device; wherein:

[0084] The first consumables supply device is at least used to provide a nucleic acid extraction container;

[0085] The second consumables supply device is at least used to provide an amplification reaction container;

[0086] The first scheduling device includes at least one consumable material transport assembly, which is used to carry the nucleic acid extraction container and / or the amplification reaction container to move along a trajectory at least partially parallel to the first horizontal direction, wherein one of the consumable material transport assemblies has a first side and a second side arranged on opposite sides along the second horizontal direction, the second consumable material supply device and the sample storage device are distributed side by side along the first horizontal direction, and at least one of the two is at least partially located on the first side of the consumable material transport assembly, at least part of the nucleic acid extraction device and at least part of the amplification device are distributed side by side along the first horizontal direction, and both are at least partially located on the second side of the consumable material transport assembly, and the second horizontal direction is approximately perpendicular to the first horizontal direction; the orthographic projection of the consumable material transport assembly on any vertical plane parallel to the first horizontal direction and the orthographic projection of the nucleic acid extraction device on the vertical plane at least partially overlap, and the orthographic projection of the consumable material transport assembly on any vertical plane parallel to the first horizontal direction and the orthographic projection of the sample storage device on the vertical plane at least partially overlap;

[0087] The sample storage device is at least used to store a sample container loaded with a sample;

[0088] The sample distributing device is used to draw at least part of the sample from the sample container provided by the sample storage device and dispense it into the nucleic acid extraction container provided by the first consumables supply device;

[0089] The nucleic acid extraction device is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container to obtain a nucleic acid extraction solution;

[0090] The pipetting device is used to draw at least part of the nucleic acid extraction solution from the nucleic acid extraction container and dispense it into the amplification reaction container provided by the second consumables supply device;

[0091] The amplification device is used to amplify the liquid in the amplification reaction container containing at least the nucleic acid extract to obtain a liquid to be tested;

[0092] The detection device is used to detect the liquid to be tested.

[0093] As an embodiment, the at least one consumable conveying assembly includes a first consumable conveying assembly and a second consumable conveying assembly, the first consumable conveying assembly has a first side and a second side arranged on opposite sides along a second horizontal direction, the second consumable supply device and the sample storage device are distributed side by side along the first horizontal direction, and the sample storage device is located on the first side of the first consumable conveying assembly, at least part of the nucleic acid extraction device and at least part of the amplification device are distributed side by side along the first horizontal direction on the second side of the first consumable conveying assembly, the second consumable conveying assembly is arranged on a side of the nucleic acid extraction device and the amplification device away from the first consumable conveying assembly along the second horizontal direction, and the second consumable conveying assembly is arranged on a side of the nucleic acid extraction device and the amplification device away from the first consumable conveying assembly along the second horizontal direction, and the second consumable supply device and the sample storage device are distributed side by side along the first horizontal direction. A consumable transport assembly is at least used to carry the nucleic acid extraction container for linear motion along the first horizontal direction, and the second consumable transport assembly is at least used to carry the amplification reaction container for linear motion along the first horizontal direction. The orthographic projection of at least one of the first consumable transport assembly and the second consumable transport assembly on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the nucleic acid extraction device on the vertical plane, and the orthographic projection of at least one of the first consumable transport assembly and the second consumable transport assembly on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the sample storage device in the vertical plane; or,

[0094] The at least one consumable transport assembly includes a first consumable transport assembly and a second consumable transport assembly, the second consumable transport assembly has a first side and a second side arranged on opposite sides along a second horizontal direction, the second consumable supply device and the sample storage device are distributed side by side along the first horizontal direction and the sample storage device is located on the first side of the second consumable transport assembly, at least part of the nucleic acid extraction device and at least part of the amplification device are distributed side by side along the first horizontal direction on the second side of the second consumable transport assembly, the first consumable transport assembly is arranged on a side of the second consumable supply device and the sample storage device away from the second consumable transport assembly, and the first consumable transport assembly The component is at least used to carry the nucleic acid extraction container for linear movement along the first horizontal direction, the second consumable material transport component is at least used to carry the amplification reaction container for linear movement along the first horizontal direction, the orthographic projection of at least one of the first consumable material transport component and the second consumable material transport component on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the nucleic acid extraction device on the vertical plane, and the orthographic projection of at least one of the first consumable material transport component and the second consumable material transport component on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the sample storage device on the vertical plane; or,

[0095] The at least one consumable transport assembly includes a third consumable transport assembly, which has a first side and a second side arranged on opposite sides along the second horizontal direction, the second consumable supply device and the sample storage device are distributed side by side along the first horizontal direction, and the sample storage device is located on the first side of the third consumable transport assembly, at least part of the nucleic acid extraction device and at least part of the amplification device are distributed side by side along the first horizontal direction on the second side of the third consumable transport assembly, and the third consumable transport assembly is used to carry the nucleic acid extraction container and the amplification reaction container to move linearly along a straight track parallel to the first horizontal direction or along a U-shaped track partially parallel to the first horizontal direction. The orthographic projection of the third consumable transport assembly on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the nucleic acid extraction device on the vertical plane, and the orthographic projection of the third consumable transport assembly on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the sample storage device on the vertical plane.

[0096] As an embodiment, the sample analyzer further includes a reagent storage device and a reagent dispensing device, wherein the reagent storage device is used to store reagents, and the reagent dispensing device is used to draw reagents from the reagent storage device and dispense them into the nucleic acid extraction container and / or the amplification reaction container;

[0097] The second consumable supply device, the reagent storage device and the sample storage device are distributed side by side along the first horizontal direction, and at least part of at least two of the second consumable supply device, the reagent storage device and the sample storage device is located on the first side of one of the consumable transport components away from the nucleic acid extraction device and the amplification device.

[0098] A third object of the present invention is to provide a sample analyzer comprising a first consumables supply device, a second consumables supply device, a sample storage device, a sample distribution device, a nucleic acid extraction device, an amplification device, a detection device, a first scheduling device, and a pipetting device; wherein:

[0099] The first consumables supply device is at least used to provide the nucleic acid extraction container;

[0100] The second consumables supply device is at least used to provide the amplification reaction container;

[0101] The first scheduling device includes a first consumable conveying assembly and a second consumable conveying assembly, the first consumable conveying assembly is at least used to carry the nucleic acid extraction container for linear movement along a first horizontal direction, the second consumable conveying assembly is at least used to carry the amplification reaction container for linear movement along the first horizontal direction, the first consumable conveying assembly and the second consumable conveying assembly are spaced apart along the second horizontal direction, the first horizontal direction is substantially perpendicular to the second horizontal direction, the first consumable conveying assembly has a first side and a second side arranged on opposite sides along the second horizontal direction, the second consumable conveying assembly has a first side and a second side arranged on opposite sides along the second horizontal direction, the second side of the first consumable conveying assembly is arranged opposite to the first side of the second consumable conveying assembly, the sample storage device, the nucleic acid extraction device and the amplification device are at least partially distributed between the second side of the first consumable conveying assembly and the first side of the second consumable conveying assembly, and the sample storage device, the nucleic acid extraction device and the amplification device are distributed side by side along the first horizontal direction;

[0102] The sample storage device is at least used to store a sample container loaded with a sample;

[0103] The sample distributing device is used to draw at least part of the sample from the sample container provided by the sample storage device and dispense it into the nucleic acid extraction container provided by the first consumables supply device;

[0104] The nucleic acid extraction device is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container to obtain a nucleic acid extraction solution;

[0105] The pipetting device is used to draw at least part of the nucleic acid extraction solution from the nucleic acid extraction container and dispense it into the amplification reaction container provided by the second consumables supply device;

[0106] The amplification device is used to amplify the liquid in the amplification reaction container containing at least the nucleic acid extract to obtain a liquid to be tested;

[0107] The detection device is used to detect the liquid to be tested.

[0108] In one embodiment, the second consumables supply device and the sample storage device are arranged side by side along the first horizontal direction, the nucleic acid extraction device and the amplification device are arranged side by side along the first horizontal direction, and the sample storage device and the nucleic acid extraction device are arranged along the second horizontal direction; and / or,

[0109] The sample analyzer also includes a reagent storage device and a reagent dispensing device, the reagent storage device is used to store reagents, and the reagent dispensing device is used to draw reagents from the reagent storage device and inject them into the nucleic acid extraction container and / or the amplification reaction container; at least part of the second consumable supply device, the reagent storage device and the sample storage device are distributed side by side along the first horizontal direction on the second side of the first consumable conveying assembly.

[0110] A fourth object of the present invention is to provide a sample analyzer comprising a first consumables supply device, a second consumables supply device, a sample storage device, a sample distribution device, a nucleic acid extraction device, an amplification device, a detection device, a first scheduling device, a pipetting device, and a third scheduling device; wherein:

[0111] The first consumables supply device is at least used to provide the nucleic acid extraction container;

[0112] The second consumables supply device is at least used to provide the amplification reaction container;

[0113] The first scheduling device has a sample loading position and a first transfer position distributed along the first horizontal direction, the first scheduling device is at least used to carry a nucleic acid extraction container for linear motion so that the nucleic acid extraction container is sequentially moved to the sample loading position and the first transfer position, the first scheduling device has a first side and a second side arranged on opposite sides along the second horizontal direction, the second horizontal direction is substantially perpendicular to the first horizontal direction, the sample storage device is at least partially located on the first side of the first scheduling device, and at least one of the nucleic acid extraction device and the amplification device is at least partially located on the second side of the first scheduling device;

[0114] The sample storage device is at least used to store a sample container loaded with a sample;

[0115] The sample distributing device is used to draw at least part of the sample from the sample container provided by the sample storage device and dispense it into the nucleic acid extraction container provided by the first consumable supply device and located at the sample loading position;

[0116] The third dispatching device is used to dispatch the nucleic acid extraction container located at the first transfer position and loaded with at least a sample to the nucleic acid extraction device;

[0117] The nucleic acid extraction device is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container to obtain a nucleic acid extraction solution;

[0118] The pipetting device is used to draw at least part of the nucleic acid extraction solution from the nucleic acid extraction container and dispense it into the amplification reaction container provided by the second consumables supply device;

[0119] The amplification device is used to amplify the liquid in the amplification reaction container containing at least the nucleic acid extract to obtain a liquid to be tested;

[0120] The detection device is used to detect the liquid to be tested.

[0121] As an embodiment, the first scheduling device further has a first reagent dispensing position, and the sample analyzer further includes a reagent storage device and a reagent dispensing device, the reagent storage device is at least used to store a first type of reagent, and the reagent dispensing device is at least used to absorb the first type of reagent from the reagent storage device and dispense it into the nucleic acid extraction container; the first scheduling device is used to carry the nucleic acid extraction container to move to the first reagent dispensing position, the sample loading position, and the first transfer position in sequence; the reagent storage device and the sample storage device are distributed side by side along the first horizontal direction and are both at least partially located on the first side of the first scheduling device, and the nucleic acid extraction device and the amplification device are distributed side by side along the first horizontal direction and are both at least partially located on the second side of the first scheduling device; and / or,

[0122] The first scheduling device also has a second reagent dispensing position, a first liquid injection position, a second transfer position, a first liquid aspiration position, and a third transfer position; the third scheduling device is also used to dispatch the nucleic acid extraction container loaded with the nucleic acid extract from the nucleic acid extraction device to the third transfer position; the first scheduling device is also used to carry the amplification reaction container from the second reagent dispensing position to the first liquid injection position and the second transfer position in sequence, and to carry the nucleic acid extraction container loaded with the nucleic acid extract from the third transfer position to the first liquid aspiration position; the reagent dispensing device is used to absorb at least part of the second type of reagent from the reagent storage device and distribute it to the reagent storage device located at the first liquid aspiration position. The sample analyzer further comprises a fifth scheduling device and a first magnetic attraction component, wherein the first magnetic attraction component is arranged beside the first liquid aspiration position to perform magnetic adsorption on the nucleic acid extract in the nucleic acid extraction container located at the first liquid aspiration position; the pipetting device is used to draw at least part of the nucleic acid extract from the nucleic acid extraction container located at the first liquid aspiration position and dispense it into the amplification reaction container located at the first liquid injection position; the fifth scheduling device is used to schedule the amplification reaction container located at the second transfer position and loaded with the nucleic acid extract and the second type of reagent to the amplification device.

[0123] A fifth object of the present invention is to provide a sample analyzer, comprising a first consumables supply device, a second consumables supply device, a sample storage device, a sample dispensing device, a reagent storage device, a reagent dispensing device, a nucleic acid extraction device, an amplification device, a detection device, a first scheduling device, a pipetting device, and a fifth scheduling device; wherein:

[0124] The first consumables supply device is at least used to provide the nucleic acid extraction container;

[0125] The second consumables supply device is at least used to provide the amplification reaction container;

[0126] The first scheduling device has a second reagent dispensing position, a first liquid injection position, and a second transfer position distributed along a first horizontal direction. The first scheduling device is at least used to carry the amplification reaction container for linear motion so that the amplification reaction container moves from the second reagent dispensing position to the first liquid injection position and the second transfer position in sequence. The reagent storage device, the sample storage device, the nucleic acid extraction device, and the amplification device are distributed on at least two sides of the first scheduling device, and two of the reagent storage device, the sample storage device, the nucleic acid extraction device, and the amplification device are distributed side by side along the first horizontal direction and are at least partially located on the same side of the first scheduling device.

[0127] The sample storage device is at least used to store a sample container loaded with a sample;

[0128] The sample distributing device is used to draw at least part of the sample from the sample container provided by the sample storage device and dispense it into the nucleic acid extraction container provided by the first consumables supply device;

[0129] The nucleic acid extraction device is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container to obtain a nucleic acid extraction solution;

[0130] The reagent dispensing device is used to draw at least part of the second type of reagent from the reagent storage device and inject it into the amplification reaction container located at the second reagent injection position;

[0131] The pipetting device is used to draw at least part of the nucleic acid extraction solution from the nucleic acid extraction container and inject it into the amplification reaction container provided by the second consumables supply device and located at the first injection position;

[0132] The fifth dispatching device is used to dispatch the amplification reaction container located at the second transfer position and loaded with the nucleic acid extract and the second type of reagent to the amplification device;

[0133] The amplification device is used to amplify the liquid in the amplification reaction container containing at least the nucleic acid extract to obtain a liquid to be tested;

[0134] The detection device is used to detect the liquid to be tested.

[0135] In one embodiment, the first scheduling device has a first side and a second side arranged on opposite sides along the second horizontal direction, the reagent storage device and the sample storage device are arranged side by side along the first horizontal direction and are both at least partially located on the first side of the first scheduling device, the nucleic acid extraction device and the amplification device are arranged side by side along the first horizontal direction and are both at least partially located on the second side of the first scheduling device, and the second horizontal direction is approximately perpendicular to the first horizontal direction; and / or,

[0136] The first scheduling device also has a third transfer position and a first liquid aspiration position; the first scheduling device is also used to carry the nucleic acid extraction container to move linearly from the third transfer position to the first liquid aspiration position; the sample analyzer also includes a third scheduling device and a first magnetic attraction component, the third scheduling device is used to schedule the nucleic acid extraction container loaded with the nucleic acid extract from the nucleic acid extraction device to the third transfer position; the first magnetic attraction component is arranged next to the first liquid aspiration position to perform magnetic adsorption on the nucleic acid extract in the nucleic acid extraction container located at the first liquid aspiration position; the pipetting device is used to absorb at least part of the nucleic acid extract from the nucleic acid extraction container located at the first liquid aspiration position and inject it into the amplification reaction container located at the first injection position.

[0137] The sample analyzer provided by the present invention is characterized in that a first consumable material transport assembly for carrying at least a nucleic acid extraction container for linear motion along a first horizontal direction and a second consumable material transport assembly for carrying at least amplification reaction container for linear motion along the first horizontal direction are arranged side by side along a second horizontal direction, at least a portion of at least one of the sample storage device, the nucleic acid extraction device and the amplification device is arranged on a first side of the first consumable material transport assembly, and at least a portion of at least another of the sample storage device, the nucleic acid extraction device and the amplification device is arranged on a second side of the second consumable material transport assembly, thus equivalent to utilizing the middle area of ​​the sample analyzer for linear scheduling of nucleic acid extraction. Taking containers and amplification reaction containers, at least parts of at least two of the sample storage device, the nucleic acid extraction device and the amplification device are distributed on the opposite side of the middle area, which is equivalent to setting two consumables conveying lines in the middle and distributing the functional modules on the opposite sides of the two consumables conveying lines, so that the two consumables conveying lines can simultaneously meet the consumables scheduling needs of the functional modules on both sides, without the need to set up a separate consumables conveying component for each functional module, which is beneficial to simplifying the consumables scheduling network of the sample analyzer, and further beneficial to improving the scheduling efficiency of the nucleic acid extraction containers and amplification reaction containers between the functional modules, and beneficial to reducing the occupied space and cost of the sample analyzer. BRIEF DESCRIPTION OF THE DRAWINGS

[0138] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying any creative work.

[0139] FIG1 is a schematic diagram of the composition of a sample analyzer provided in Example 1 of the present invention;

[0140] FIG2 is a schematic diagram of the horizontal distribution of a sample analyzer within a space of one floor provided by the first embodiment of the present invention;

[0141] FIG3 is a schematic diagram of a process of transporting a nucleic acid extraction container carried by a first consumables transport assembly provided in Example 1 of the present invention;

[0142] FIG4 is a schematic diagram of a process of transporting an amplification reaction container carried by a second consumables transport assembly provided in Example 1 of the present invention;

[0143] FIG5 is a schematic top view of the first movable seat provided in Example 1 of the present invention;

[0144] FIG6 is a schematic top view of the second movable base provided in the first embodiment of the present invention;

[0145] 7 is a schematic assembly diagram of the first dispatching device, the pipetting device, and the first magnetic adsorption component provided in Example 1 of the present invention from one perspective;

[0146] FIG8 is a partial enlarged schematic diagram of FIG7;

[0147] FIG9 is a schematic assembly diagram of the first dispatching device, the pipetting device, and the first magnetic adsorption component from another perspective provided in Example 1 of the present invention;

[0148] FIG10 is a partial enlarged schematic diagram of FIG9;

[0149] 11 is a schematic diagram of the distribution of a second consumables supply device and a reagent storage device provided in Example 1 of the present invention;

[0150] 12 is a schematic diagram of the distribution of the first consumables supply device, the second consumables supply device and the reagent storage device provided in Example 1 of the present invention;

[0151] 13 is a schematic structural diagram of a nucleic acid extraction container, a first pipette tip, and a second pipette tip provided in Example 1 of the present invention;

[0152] FIG14 is a schematic structural diagram of an amplification reaction container and a container cover provided in Example 1 of the present invention;

[0153] 15 is a schematic structural diagram of the integrated reagent dispensing device, the fourth scheduling device, and the cover removal device provided in Example 1 of the present invention;

[0154] FIG16 is a schematic diagram of the internal layout of the nucleic acid extraction device provided in Example 1 of the present invention;

[0155] FIG17 is a schematic diagram of the horizontal distribution of a sample analyzer within a space of a second embodiment of the present invention;

[0156] FIG18 is a schematic diagram of the horizontal distribution of a sample analyzer within a space of a layer according to a third embodiment of the present invention;

[0157] FIG19 is a schematic diagram of the horizontal distribution of a sample analyzer within a space of a first floor provided by a fourth embodiment of the present invention;

[0158] FIG20 is a schematic diagram of the horizontal distribution of a sample analyzer within a space of a layer according to a fifth embodiment of the present invention;

[0159] FIG21 is a schematic diagram of the horizontal distribution of a sample analyzer within a space of one floor provided by the sixth embodiment of the present invention. DETAILED DESCRIPTION

[0160] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.

[0161] In addition, the technical solutions of various embodiments may be combined with each other, but this must be based on the fact that they can be implemented by ordinary technicians in this field.

[0162] Example 1:

[0163] As shown in Figures 1 to 16, the sample analyzer 10 provided in the first embodiment of the present invention includes a sample distribution device 100, a nucleic acid extraction device 200, an amplification device 300, and a detection device 400. The sample distribution device 100 is used to distribute samples; the nucleic acid extraction device 200 is used to extract nucleic acids from a liquid containing at least a sample to obtain a nucleic acid extract solution; the amplification device 300 is used to amplify the liquid containing at least a nucleic acid extract solution to obtain a test solution; and the detection device 400 is used to detect the test solution. The nucleic acid extraction device 200 is mainly used to extract nucleic acids from the sample to obtain purified nucleic acids. The amplification device 300 is configured to amplify the nucleic acids extracted by the nucleic acid extraction device 200 to significantly increase the amount of nucleic acids in a relatively short period of time. The sample analyzer 10 provided in this embodiment is mainly used to obtain a test solution by extracting and amplifying nucleic acids from the sample, and then detecting the test solution to obtain a test result of the sample.

[0164] As an embodiment, the sample analyzer 10 further includes a first consumables supply device 500, a second consumables supply device 600, a pipetting device 700, and a sample storage device 800. The first consumables supply device 500 is at least used to provide a nucleic acid extraction container 20. The second consumables supply device 600 is at least used to provide an amplification reaction container 30. The sample distribution device 100 is used to draw at least part of the sample from the sample container and dispense it into the nucleic acid extraction container 20 provided by the first consumables supply device 500; the nucleic acid extraction device 200 is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container 20 to obtain a nucleic acid extract; the pipetting device 700 is used to draw at least part of the nucleic acid extract from the nucleic acid extraction container 20 and dispense it into the amplification reaction container 30 provided by the second consumables supply device 600; the amplification device 300 is used to amplify the liquid containing at least the nucleic acid extract in the amplification reaction container 30 to obtain a liquid to be tested. The sample container, nucleic acid extraction container 20, and amplification reaction container 30 are three different containers. The pipetting device 700 is primarily used to transfer nucleic acid extract solution between the nucleic acid extraction container 20 and the amplification reaction container 30. The sample container is primarily used to hold samples collected from patients, that is, the sample container primarily provides a storage space for the samples. It is understood that the sample in the sample container may also be a sample that has been pre-processed after collection. The nucleic acid extraction container 20 is primarily used to hold samples for nucleic acid extraction, that is, the nucleic acid extraction container 20 primarily provides a storage space for nucleic acid extraction. The amplification reaction container 30 is primarily used to hold nucleic acid extract solution for amplification reactions, that is, the amplification reaction container 30 primarily provides a storage space for nucleic acid extract solution. The sample storage device 800 is used to store at least sample containers containing samples. These sample containers can be manually loaded into the sample storage device 800 by a user or automatically loaded by an automatic sample loading device. The sample dispensing device 100 is used to aspirate at least a portion of the sample from the sample container provided by the sample storage device 800 and dispense it into the nucleic acid extraction container 20 provided by the first consumables supply device 500. The nucleic acid extraction container 20 and the amplification reaction container 30 are two different consumables of the sample analyzer 10. In this way, the nucleic acid extraction container 20 can be designed into a shape that is convenient for nucleic acid extraction, and the amplification reaction container 30 can be designed into a shape that is convenient for amplification reaction, as required. The nucleic acid extraction container 20 and the amplification reaction container 30 are used as consumables. Specifically, the nucleic acid extraction container 20 and the amplification reaction container 30 are both disposable containers. After completing the nucleic acid extraction of a test item, a nucleic acid extraction container 20 is discarded and recycled. After completing the amplification reaction and detection of a test item, an amplification reaction container 30 is discarded and recycled without the need for cleaning and recycling. This can eliminate the container cleaning step in the detection process, thereby improving detection efficiency and avoiding the problem of cross contamination caused by unclean cleaning affecting the accuracy of sample detection results.Each sample tested on the sample analyzer 10 consumes at least one nucleic acid extraction container 20 and at least one amplification reaction container 30. This embodiment uses a first consumables supply device 500 to provide nucleic acid extraction containers 20, and a second consumables supply device 600 to provide amplification reaction containers 30. This meets the needs of continuous testing of batches of samples and helps avoid situations where a shortage of amplification nucleic acid extraction containers 20 and reaction containers could affect sample testing efficiency.

[0165] As an embodiment, the first consumable supply device 500 is used to store the nucleic acid extraction containers 20 , that is, the first consumable supply device 500 can buffer a certain amount of nucleic acid extraction containers 20 to meet the supply demand of batch nucleic acid extraction containers 20 .

[0166] As an embodiment, the first consumables supply device 500 is also used to allow an operator or an operating robot to place the nucleic acid extraction container 20 to load the nucleic acid extraction container 20. That is, the storage position and loading position of the nucleic acid extraction container 20 are located at the same position on the sample analyzer 10. Of course, in specific applications, as an alternative embodiment, the storage position and loading position of the nucleic acid extraction container 20 on the sample analyzer 10 can also be located in two different positions.

[0167] As an embodiment, the second consumable supply device 600 is used to store the amplification reaction containers 30 , that is, the second consumable supply device 600 can buffer a certain amount of amplification reaction containers 30 to meet the supply demand of batch amplification reaction containers 30 .

[0168] As an embodiment, the second consumables supply device 600 is also used to allow an operator or an operating robot to place the amplification reaction container 30 to load the amplification reaction container 30. That is, the storage position and loading position of the amplification reaction container 30 are located at the same location on the sample analyzer 10. Of course, in specific applications, as an alternative embodiment, the storage position and loading position of the amplification reaction container 30 on the sample analyzer 10 can also be located in two different locations.

[0169] In one embodiment, the sample storage device 800 is used to store at least sample containers containing samples. The sample dispensing device 100 is used to aspirate at least a portion of the sample from the sample container provided by the sample storage device 800 and dispense it into the nucleic acid extraction container 20 provided by the first consumables supply device 500. The sample storage device 800 can store a certain number of sample containers to meet the needs of continuous testing of batch samples.

[0170] As an embodiment, the sample storage device 800 is also used for an operator or an operating robot to place a sample container for loading the sample container. That is, the storage position and loading position of the sample container are located at the same location on the sample analyzer 10. Of course, in specific applications, as an alternative embodiment, the storage position and loading position of the sample container on the sample analyzer 10 can also be located in two different locations.

[0171] As an embodiment, the sample container is provided with an identification code, which is associated with at least the test item information of the sample in the sample container. The sample analyzer 10 further includes an information acquisition component, which is used to identify the identification code to obtain at least the test item information of the sample.

[0172] As an embodiment, the sample analyzer 10 also includes a first scheduling device 900, which is used to schedule the nucleic acid extraction container 20 provided by the first consumable supply device 500 and / or to schedule the amplification reaction container 30 provided by the second consumable supply device 600, that is, the first scheduling device 900 is used to schedule at least one of the two consumables, the nucleic acid extraction container 20 and the amplification reaction container 30.

[0173] As an embodiment, the first scheduling device 900 is used to schedule the nucleic acid extraction container 20 provided by the first consumable supply device 500 and to schedule the amplification reaction container 30 provided by the second consumable supply device 600, that is, the first scheduling device 900 is used to schedule both the nucleic acid extraction container 20 and the amplification reaction container 30.

[0174] As an embodiment, the first scheduling device 900 is used to carry the nucleic acid extraction container 20 for linear motion along the first horizontal direction X, and is used to carry the amplification reaction container 30 for linear motion along the first horizontal direction X. The first scheduling device 900 is mainly used to output linear motion. In this embodiment, the trajectory of the nucleic acid extraction container 20 driven by the first scheduling device 900 is a linear trajectory, and the trajectory of the amplification reaction container 30 driven by the first scheduling device 900 is also a linear trajectory. This helps to simplify the scheduling scheme of the nucleic acid extraction container 20 and the amplification reaction container 30, thereby helping to improve the scheduling efficiency of the nucleic acid extraction container 20 and the amplification reaction container 30 and reduce the scheduling cost of the nucleic acid extraction container 20 and the amplification reaction container 30.

[0175] As an embodiment, the first scheduling device 900 includes a first consumable conveying assembly 910 and a second consumable conveying assembly 920. The first consumable conveying assembly 910 is at least used to carry the nucleic acid extraction container 20 for linear motion along the first horizontal direction X, and the second consumable conveying assembly 920 is at least used to carry the amplification reaction container 30 for linear motion along the first horizontal direction X. The first consumable conveying assembly 910 and the second consumable conveying assembly 920 are arranged side by side along the second horizontal direction Y, and the second horizontal direction Y is approximately perpendicular to the first horizontal direction X. The first consumable conveying assembly 910 and the second consumable conveying assembly 920 are two consumable conveying assemblies that can independently transport consumables, that is, the first consumable conveying assembly 910 and the second consumable conveying assembly 920 can operate in parallel. The first consumable conveying assembly 910 and the second consumable conveying assembly 920 are arranged side by side along the second horizontal direction Y. Specifically, the first consumable conveying assembly 910 and the second consumable conveying assembly 920 are distributed along the second horizontal direction Y and are approximately parallel to each other. The first consumable conveying assembly 910 and the second consumable conveying assembly 920 may be in contact with each other or there may be a gap between them, as long as it does not affect the carrying of consumables by the two. The second horizontal direction Y is approximately perpendicular to the first horizontal direction X, including: the angle formed by the intersection of the second horizontal direction Y and the first horizontal direction X is 90°, and the angle formed by the intersection of the second horizontal direction Y and the first horizontal direction X is slightly larger or slightly smaller than 90° within a certain range. The first consumable conveying assembly 910 and the second consumable conveying assembly 920 are approximately parallel, including: the first consumable conveying assembly 910 and the second consumable conveying assembly 920 are parallel to each other, and there is an inclination angle between the first consumable conveying assembly 910 and the second consumable conveying assembly 920 within a certain small range. In this embodiment, the first scheduling device 900 is configured to include a first consumable conveying assembly 910 and a second consumable conveying assembly 920, so that at least part of the nucleic acid extraction container 20 and the amplification reaction container 30 can be scheduled in parallel, which is beneficial to improving scheduling efficiency.

[0176] As an embodiment, the second horizontal direction Y is substantially perpendicular to the first horizontal direction X, including: an angle formed by the intersection of the second horizontal direction Y and the first horizontal direction X is 90°±10°.

[0177] As an embodiment, the second horizontal direction Y is perpendicular to the first horizontal direction X, that is, the angle formed by the intersection of the second horizontal direction Y and the first horizontal direction X is 90°.

[0178] As an embodiment, the first consumable material conveying assembly 910 and the second consumable material conveying assembly 920 are substantially parallel, including: the first consumable material conveying assembly 910 and the second consumable material conveying assembly 920 have a relative inclination angle of 0°±10°.

[0179] As an embodiment, the first consumable material conveying assembly 910 and the second consumable material conveying assembly 920 are parallel, that is, the first consumable material conveying assembly 910 and the second consumable material conveying assembly 920 have a relative inclination angle of 0°.

[0180] As an embodiment, the first consumable material conveying assembly 910 has a first side and a second side arranged on opposite sides along the second horizontal direction Y, and the second consumable material conveying assembly 920 has a first side and a second side arranged on opposite sides along the second horizontal direction Y. The second side of the first consumable material conveying assembly 910 is adjacent to the first side of the second consumable material conveying assembly 920, and at least a portion of at least one of the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 is located on the first side of the first consumable material conveying assembly 910, and at least a portion of at least another of the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 is located on the second side of the second consumable material conveying assembly 920. In this embodiment, the consumables conveying components of the nucleic acid extraction container 20 and the amplification reaction container 30 are arranged in the middle area, and at least parts of at least two of the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 are arranged on the opposite side of the middle area, which is equivalent to setting two consumables conveying lines in the middle and distributing the functional modules on the opposite sides of the two consumables conveying lines. In this way, the two consumables conveying lines can simultaneously meet the consumables scheduling needs of the functional modules on both sides without the need to set up a separate consumables conveying component for each functional module, which is beneficial to simplifying the consumables scheduling network of the sample analyzer 10, and further beneficial to improving the scheduling efficiency of the nucleic acid extraction container and the amplification reaction container 30 between the functional modules, and beneficial to reducing the volume and cost of the sample analyzer 10.

[0181] In one embodiment, the first consumable transport assembly 910 includes a first guide rail 911, a first movable seat 912, and a first drive mechanism 913. The first guide rail 911 extends along a first horizontal direction X. The first movable seat 912 is movably connected to the first guide rail 911 to carry the nucleic acid extraction container 20 for linear motion along the first guide rail 911. The first drive mechanism 913 is used to drive the first movable seat 912 for linear motion along the first guide rail 911. The first movable seat 912 is movably connected to the first guide rail 911. Specifically, after being mounted on the first guide rail 911, the first movable seat 912 can still move along the first guide rail 911 under the action of an external force. The first movable seat 912 primarily serves as a carrier for the nucleic acid extraction container 20 on the first consumable transport assembly 910. The first guide rail 911 primarily defines the motion trajectory of the first movable seat 912, thereby limiting the trajectory of the nucleic acid extraction container 20 transported by the first consumable transport assembly 910. Specifically, the first consumable transport assembly 910 can only transport the nucleic acid extraction container 20 along the length of the first guide rail 911. The first drive mechanism 913 is primarily used to provide driving force for the movement of the first movable seat 912, thereby providing driving force for the nucleic acid extraction container 20 transported by the first consumable material transport assembly 910. In this embodiment, the motion output by the first consumable material transport assembly 910 is a one-dimensional linear motion, which has a simple structure and low cost. In addition, in this embodiment, the nucleic acid extraction container 20 is guided by the first guide rail 911 for linear motion along the first horizontal direction X, and the first movable seat 912 is used as a carrier to carry the nucleic acid extraction container 20 for movement. This helps to reduce the shape design requirements of the nucleic acid extraction container 20, and the shape design of the first movable seat 912 is matched to the load-bearing requirements of the nucleic acid extraction container 20. Of course, in specific applications, the nucleic acid extraction container 20 is not limited to being driven by the first guide rail 911 and the first movable seat 912 for linear motion. For example, as an alternative embodiment, the nucleic acid extraction container 20 can also be placed on a conveyor belt by the movable seat for linear motion. Alternatively, as another alternative embodiment, the bottom of the nucleic acid extraction container 20 can be set to a flat surface, so that the nucleic acid extraction container 20 can be placed directly on the conveyor belt for linear motion without the support of the movable seat.

[0182] As an embodiment, the first driving mechanism 913 includes a first motor and a first transmission mechanism. The first transmission mechanism is connected to the first motor and the first movable seat 912. The first transmission mechanism may include a synchronous belt transmission mechanism.

[0183] As an embodiment, the second consumable material transport assembly 920 includes a second guide rail 921, a second movable seat 922, and a second drive mechanism 923. The second guide rail 921 extends along the first horizontal direction X. The second movable seat 922 is at least used to carry the amplification reaction container 30 for linear motion along the second guide rail 921. The second drive mechanism 923 is used to drive the second movable seat 922 for linear motion along the second guide rail 921; wherein the first guide rail 911 and the second guide rail 921 are arranged side by side along the second horizontal direction Y. The working principles of the second movable seat 922, the second guide rail 921, and the second drive mechanism 923 are similar to those of the first movable seat 912, the first guide rail 911, and the first drive mechanism 913, except that the consumables transported by the two are different. In this embodiment, the motion output by the second consumable material transport assembly 920 is a one-dimensional linear motion, which has a simple structure and low cost. In addition, this embodiment uses the second guide rail 921 to guide the nucleic acid extraction container 20 for linear motion along the first horizontal direction X, and uses the second movable seat 922 as a carrier to carry the amplification reaction container 30 for movement, which helps to reduce the shape design requirements of the amplification reaction container 30, and the shape design of the second movable seat 922 matches the load-bearing requirements of the amplification reaction container 30. Of course, in specific applications, the amplification reaction container 30 is not limited to being driven by the second guide rail 921 and the second movable seat 922 for linear motion. For example, as an alternative embodiment, the amplification reaction container 30 can also be placed on a conveyor belt via the movable seat for linear motion; or, as another alternative embodiment, the bottom of the amplification reaction container 30 can also be set to a flat surface, so that the amplification reaction container 30 can be placed directly on a conveyor belt for linear motion without being carried by the movable seat.

[0184] As an embodiment, the second driving mechanism 923 includes a second motor and a second transmission mechanism, the second transmission mechanism is transmission-connected to the second motor and the second movable base 922, and the first transmission mechanism may include a synchronous belt transmission mechanism.

[0185] As one embodiment, a first receiving groove 9121 for placing a nucleic acid extraction container 20 is provided on the top of the first movable seat 912. The sample analyzer 10 also includes a second scheduling device 103 and a third scheduling device 104. The second scheduling device 103 is used to place the nucleic acid extraction container 20 provided by the first consumable supply device 500 from above the first movable seat 912 into the first receiving groove 9121. The third scheduling device 104 is used to remove the nucleic acid extraction container 20 placed in the first receiving groove 9121 and loaded with at least a sample from above the first movable seat 912 and dispatch it to the nucleic acid extraction device 200. The first receiving groove 9121 has a first access opening that is open upward. The first access opening is used for taking and placing the nucleic acid extraction container 20 on the first movable seat 912. The first movable seat 912 is primarily used to carry the nucleic acid extraction container 20 and move it linearly along the first guide rail 911 to a working position that interacts with the functional modules on both sides of it. The second dispatching device 103 is at least used to dispatch the nucleic acid extraction container 20 between the first consumable supply device 500 and the first movable seat 912. The third dispatching device 104 is at least used to dispatch the nucleic acid extraction container 20 between the first movable seat 912 and the nucleic acid extraction device 200. The first movable seat 912 is similar to a dispatching vehicle, and the second dispatching device 103 and the third dispatching device 104 are similar to robotic arms. In this embodiment, the nucleic acid extraction container 20 is linearly dispatched to a working position interacting with the functional modules on both sides thereof by using a first movable seat 912 similar to a dispatching vehicle, so that the working space of the first consumable material transport component 910 and the working space in the sample analyzer 10 are arranged vertically. The first consumable material transport component 910 will not interfere with the movement of the manipulator in the sample analyzer 10. In this way, on the one hand, since the first consumable material transport component 910 only outputs one-dimensional linear motion and does not need to move up and down, it is beneficial to improve the dispatch efficiency of the nucleic acid extraction container 20; on the other hand, the upper and lower spaces can be fully utilized to arrange the various consumable material dispatching devices of the sample analyzer 10, which is beneficial to reducing the space occupied by the consumable material dispatching devices in the sample analyzer 10 and facilitating the miniaturization design of the sample analyzer 10; on the other hand, it can be beneficial to reduce the number of manipulators in the sample analyzer 10, thereby simplifying the consumable material dispatching network in the sample analyzer 10, reducing the cost of the sample analyzer 10, and avoiding cross contamination between the various functional modules.

[0186] As an embodiment, the second scheduling device 103 includes a third clamping device and a third driving mechanism. The third clamping device is used to clamp and release the nucleic acid extraction container 20. The third driving mechanism is used to drive the third clamping device to move in three-dimensional or two-dimensional space, so that at least the third clamping device can drive the nucleic acid extraction container 20 to be scheduled from the first consumable supply device 500 to the first movable seat 912.

[0187] As an embodiment, the third scheduling device 104 includes a fourth clamping device and a fourth driving mechanism. The fourth clamping device is used to clamp and release the nucleic acid extraction container 20. The fourth driving mechanism is used to drive the fourth clamping device to move in three-dimensional or two-dimensional space, so that at least the fourth clamping device can drive the nucleic acid extraction container 20 to be scheduled from the first movable seat 912 to the nucleic acid extraction device 200.

[0188] As an embodiment, a second receiving groove 9221 for placing an amplification reaction vessel 30 is provided on the top of the second movable seat 922. The sample analyzer 10 further includes a fourth dispatching device 105 and a fifth dispatching device 106. The fourth dispatching device 105 is used to place the amplification reaction vessel 30 provided by the second consumables supply device 600 from above the second movable seat 922 into the second receiving groove 9221. The fifth dispatching device 106 is used to remove the amplification reaction vessel 30 placed in the second receiving groove 9221 and loaded with at least a nucleic acid extract from above the second movable seat 922 and dispatch it to the amplification device 300. The second receiving groove 9221 has a second access opening that is open upward, and the second access opening is used for taking and placing the amplification reaction vessel 30 on the second movable seat 922. The second movable seat 922 is primarily used to carry the amplification reaction container 30 and perform linear motion along the second guide rail 921 to a working position that interacts with the functional modules on either side thereof. The fourth dispatching device 105 is at least used to dispatch the amplification reaction container 30 between the second consumables supply device 600 and the second movable seat 922, and the fifth dispatching device 106 is at least used to dispatch the amplification reaction container 30 between the second movable seat 922 and the amplification device 300. The second movable seat 922 is similar to a dispatching vehicle, and the fourth dispatching device 105 and the fifth dispatching device 106 are similar to manipulators. The amplification reaction container 30 is dispatched using a dispatching vehicle-like method, and the beneficial effects achieved are similar to those achieved by dispatching the nucleic acid extraction container 20 using a dispatching vehicle-like method, and will not be described in detail here.

[0189] As an embodiment, the first consumable material transport assembly 910 is used to carry the nucleic acid extraction container 20 for movement but is not used to carry the amplification reaction container 30 for movement, that is, the first consumable material transport assembly 910 is specifically used to carry the nucleic acid extraction container 20 for movement, but cannot carry the amplification reaction container 30 for movement.

[0190] As an embodiment, the second consumable material transport assembly 920 is used to carry the amplification reaction container 30 for movement and can be used to carry the nucleic acid extraction container 20 for movement, that is, the second consumable material transport assembly 920 can carry both the amplification reaction container 30 for movement and the nucleic acid extraction container 20 for movement, which meets the scheduling requirements of various functional modules for the nucleic acid extraction container 20.

[0191] As an embodiment, the second movable seat 922 is also used to carry the nucleic acid extraction container 20 for linear movement along the second guide rail 921, that is, the second movable seat 922 in this embodiment is used to carry both the amplification reaction container 30 and the nucleic acid extraction container 20 for movement.

[0192] As one embodiment, the top of the second movable seat 922 is further provided with a third receiving groove 9222 for placing the nucleic acid extraction container 20. The third dispatching device 104 is further used to dispatch the nucleic acid extraction container 20 loaded with nucleic acid extraction solution from the nucleic acid extraction device 200 to the top of the second movable seat 922 and place the nucleic acid extraction container 20 from above the second movable seat 922 into the third receiving groove 9222, as well as to remove the nucleic acid extraction container 20 placed in the third receiving groove 9222 from above the second movable seat 922 and dispatch it to the recovery position for recovery. The third receiving groove 9222 has a third access opening that is open upward, and the third access opening is used for the nucleic acid extraction container 20 to be taken out and placed on the second movable seat 922. In this embodiment, the third scheduling device 104 is used not only to schedule the nucleic acid extraction container 20 between the first movable seat 912 and the nucleic acid extraction device 200, but also to time-share multiplex the scheduling of the nucleic acid extraction container 20 between the nucleic acid extraction device 200 and the second movable seat 922, and to schedule the nucleic acid extraction container 20 between the second movable seat 922 and the recovery position. This helps to reduce the number of manipulators in the sample analyzer 10, thereby helping to reduce the cost of the sample analyzer 10 and simplify the consumable scheduling network. Of course, in a specific application, as an alternative embodiment, the nucleic acid extraction container 20 between the nucleic acid extraction device 200 and the second movable seat 922 can also be scheduled by other scheduling devices different from the third scheduling device 104 instead of the third scheduling device 104; or, as another alternative embodiment, the nucleic acid extraction container 20 between the second movable seat 922 and the recovery position can also be scheduled by other scheduling devices different from the third scheduling device 104 instead of the third scheduling device 104.

[0193] As an embodiment, the third receiving groove 9222 and the second receiving groove 9221 are distributed along the first horizontal direction X on the second movable seat 922 .

[0194] As an embodiment, the orthographic projection of any one of the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 on any vertical plane parallel to the first horizontal direction X at least partially overlaps with the orthographic projection of the first guide rail 911 on the vertical plane, that is, the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 are not completely misaligned with the first guide rail 911 along the first horizontal direction X, which is conducive to reducing the size of the sample analyzer 10 in the first horizontal direction X.

[0195] As an embodiment, the orthographic projection of any one of the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 on any vertical plane parallel to the first horizontal direction X at least partially overlaps with the orthographic projection of the second guide rail 921 on the vertical plane, that is, the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 are not completely misaligned with the second guide rail 921 along the first horizontal direction X, which is conducive to reducing the size of the sample analyzer 10 in the first horizontal direction X.

[0196] In one embodiment, the sample storage device 800 is located on a first side of the first consumable transport assembly 910, and at least a portion of at least one of the nucleic acid extraction device 200 and the amplification device 300 is located on a second side of the second consumable transport assembly 920. That is, the first consumable transport assembly 910 is located between the sample storage device 800 and the second consumable transport assembly 920 along the second horizontal direction Y. In this embodiment, the first consumable transport assembly 910 is located closer to the sample storage device 800 than the second consumable transport assembly 920; and the second consumable transport assembly 920 is located closer to at least one of the nucleic acid extraction device 200 and the amplification device 300 than the first consumable transport assembly 910. Since samples stored in the sample storage device 800 are primarily used for dispensing into the nucleic acid extraction container 20, positioning the first consumable transport assembly 910, which is used to dispatch the nucleic acid extraction container 20, closer to the sample storage device 800 helps reduce the travel distance of the sample dispensing device 100 when dispensing samples, thereby improving the detection efficiency of the sample analyzer 10 and reducing the risk of sample contamination. Of course, in specific applications, the relative positional relationship among the sample storage device 800, the nucleic acid extraction device 200, the amplification device 300, the first consumable material conveying assembly 910, and the second consumable material conveying assembly 920 is not limited to this. For example, as an alternative embodiment, the relative positional relationship among the sample storage device 800, the nucleic acid extraction device 200, the amplification device 300, the first consumable material conveying assembly 910, and the second consumable material conveying assembly 920 may also be: the sample storage device 800 is located on the second side of the second consumable material conveying assembly 920, and at least a portion of at least one of the nucleic acid extraction device 200 and the amplification device 300 is located on the first side of the first consumable material conveying assembly 910.

[0197] In one embodiment, at least portions of the sample storage device 800, the nucleic acid extraction device 200, and the amplification device 300 are distributed along the first horizontal direction X on the same side of the first scheduling device 900. That is, at least portions of the sample storage device 800, the nucleic acid extraction device 200, and the amplification device 300 are distributed side by side along the first horizontal direction X and on the same side of the first scheduling device 900. In this embodiment, the sample storage device 800, the nucleic acid extraction device 200, and the amplification device 300 are all distributed around the first scheduling device 900. Since two of the sample storage device 800, the nucleic acid extraction device 200, and the amplification device 300 are distributed along the first horizontal direction X, and at least portions of the other two are distributed along the second horizontal direction Y on the opposite side of the first scheduling device 900, that is, two of the sample storage device 800, the nucleic acid extraction device 200, and the amplification device 300 are distributed along the first horizontal direction X and two along the second horizontal direction Y, rather than being arranged in a straight line along a single horizontal direction, this layout scheme can effectively reduce the size of the sample analyzer 10 in a single horizontal direction, thereby improving the space utilization of the molecular laboratory.

[0198] In one embodiment, the sample storage device 800 is located on a first side of the first consumable transport assembly 910, and the nucleic acid extraction device 200 and the amplification device 300 are both at least partially located on a second side of the second consumable transport assembly 920, with the nucleic acid extraction device 200 and the amplification device 300 arranged side by side along the first horizontal direction X. In this embodiment, the sample storage device 800 is disposed on one of the two opposing sides of the first dispatching device 900, and at least a portion of the nucleic acid extraction device 200 and at least a portion of the amplification device 300 are disposed on the other side. This not only reduces the size of the sample analyzer 10 in a single horizontal direction, but also shortens the travel distance between the nucleic acid extract extracted by the nucleic acid extraction device 200 and the amplification device 300, thereby improving the detection efficiency of the sample analyzer 10 and reducing sample contamination of the nucleic acid extraction system and the amplification reaction system by the sample area. Of course, in specific applications, the distribution of the sample storage device 800, the nucleic acid extraction device 200, the amplification device 300, the first consumable material transport assembly 910 and the second consumable material transport assembly 920 is not limited to this. For example, as an alternative embodiment, the sample storage device 800 and the nucleic acid extraction device 200 are at least partially located on the first side of the first consumable material transport assembly 910, and the amplification device 300 is at least partially located on the second side of the second consumable material transport assembly 920, and the sample storage device 800 and the nucleic acid extraction device 200 are arranged side by side along the first horizontal direction X; or, as another alternative embodiment, the sample storage device 800 and the amplification device 300 are at least partially located on the first side of the first consumable material transport assembly 910, and the nucleic acid extraction device 200 is at least partially located on the second side of the second consumable material transport assembly 920, and the sample storage device 800 and the amplification device 300 are arranged side by side along the first horizontal direction X.

[0199] As an embodiment, the sample analyzer 10 further includes a reagent storage device 101 and a reagent dispensing device 102. The reagent storage device 101 is used to store reagents, and the reagent dispensing device 102 is used to dispense the reagents provided by the reagent storage device 101 into the nucleic acid extraction container 20 and / or the amplification reaction container 30. In this embodiment, the reagent dispensing device 102 is used to dispense the reagents into the nucleic acid extraction container 20 and / or the amplification reaction container 30. Of course, in specific applications, as an alternative embodiment, the reagents can also be pre-stored in the nucleic acid extraction container 20 and / or the amplification reaction container 30. In this case, the sample analyzer 10 may also be provided with the reagent storage device 101 and the reagent dispensing device 102.

[0200] As an embodiment, the reagent storage device 101 is also used for an operator or an operating robot to place reagents for loading the reagents, that is, the reagent storage position and the loading position are located at the same location on the sample analyzer 10. Of course, in specific applications, as an alternative embodiment, the reagent storage position and the loading position on the sample analyzer 10 can also be located in two different locations.

[0201] As an embodiment, the orthographic projection of any one of the reagent storage device 101, the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 on any vertical plane parallel to the first horizontal direction X at least partially overlaps with the orthographic projection of the first guide rail 911 on the vertical plane, that is, the reagent storage device 101, the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 are not completely misaligned with the first guide rail 911 along the first horizontal direction X, which is conducive to reducing the size of the sample analyzer 10 in the first horizontal direction X.

[0202] As an embodiment, the orthographic projection of any one of the reagent storage device 101, the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 on any vertical plane parallel to the first horizontal direction X at least partially overlaps with the orthographic projection of the second guide rail 921 on the vertical plane, that is, the reagent storage device 101, the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 are not completely misaligned with the second guide rail 921 along the first horizontal direction X.

[0203] As an embodiment, the reagent storage device 101 and at least one of the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 are distributed side by side along the first horizontal direction X, and the reagent storage device 101 and at least one of the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 are at least partially distributed on the same side of the first scheduling device 900. This is conducive to reducing the size of the sample analyzer 10 in the second horizontal direction Y.

[0204] As an embodiment, the reagent storage device 101 and the sample storage device 800 are arranged side by side along the first horizontal direction X, and are at least partially arranged on the same side of the first scheduling device 900. In this embodiment, the reagent storage device 101 and the sample storage device 800 are arranged on the same side of the first scheduling device 900, which facilitates the operator or the operating robot to load the reagent and sample on the same side of the sample analyzer 10.

[0205] As an embodiment, the reagent storage device 101 and the sample storage device 800 are arranged side by side on a first side of the first consumable material transport assembly 910 along the first horizontal direction X. In this embodiment, the first consumable material transport assembly 910 for dispatching the nucleic acid extraction container 20 is arranged adjacent to the reagent storage device 101 and the sample storage device 800. The distance between the reagent storage device 101 and the sample storage device 800 and the first consumable material transport assembly 910 is shorter than the distance between the reagent storage device 101 and the sample storage device 800 and the second consumable material transport assembly 920. This helps to reduce the travel distance of the sample dispensing device 100 when dispensing the sample from the sample storage device 800 to the nucleic acid extraction container 20, and helps to reduce the travel distance of the reagent dispensing device 102 when dispensing the reagent from the reagent storage device 101 to the nucleic acid extraction container 20, thereby improving the distribution efficiency of samples and reagents.

[0206] As an embodiment, the reagent storage device 101 includes a first reagent storage component 1011 and a second reagent storage component 1012, and the reagent dispensing device 102 includes a first reagent dispensing component and a second reagent dispensing component; wherein the first reagent storage component 1011 is used to store a first type of reagent, and the first reagent dispensing component is used to draw the first type of reagent from the first reagent storage component 1011 and dispense it into the nucleic acid extraction container 20, and the nucleic acid extraction device 200 is used to extract nucleic acid from the liquid in the nucleic acid extraction container 20 containing at least the sample and the first type of reagent to obtain a nucleic acid extract solution; the second reagent storage component 1012 is used to store a second type of reagent, and the second reagent dispensing component is used to draw the second type of reagent from the second reagent storage component 1012 and dispense it into the amplification reaction container 30, and the amplification device 300 is used to amplify the liquid in the amplification reaction container 30 containing at least the nucleic acid extract solution and the second type of reagent to obtain a test solution. The first type of reagent is mainly used for nucleic acid extraction and is also called an extraction reagent. The second type of reagent is mainly used for amplification reaction and is also called an amplification reagent. In this embodiment, the extraction reagent is dispensed into the nucleic acid extraction container 20 by aspiration, and the amplification reagent is dispensed into the amplification reaction container 30 by aspiration. Of course, in specific applications, as an alternative embodiment, one of the extraction reagent and the amplification reagent may be pre-stored in a container, for example, the extraction reagent may be pre-stored in the nucleic acid extraction container 20, or the amplification reagent may be pre-stored in the amplification reaction container 30.

[0207] As an embodiment, at least a portion of the second consumables supply device 600, the first reagent storage assembly 1011, the second reagent storage assembly 1012, and the sample storage device 800 are arranged side by side along the first horizontal direction X. The first consumables conveying assembly 910 extends past the side of the second consumables supply device 600, the side of the first reagent storage assembly 1011, the side of the second reagent storage assembly 1012, and the side of the sample storage device 800. In this embodiment, the consumables area, the reagent area, and the sample area are located on the same side of the sample analyzer 10. This not only helps to reduce the dispensing distance of reagents and samples, but also facilitates the operator or operating robot to perform the loading operation of the amplification reaction container 30, the first type of reagent, the second type of reagent, and the sample on the same side of the sample analyzer 10. Of course, in specific applications, the distribution of the second consumable supply device 600, the first reagent storage component 1011, the second reagent storage component 1012, and the sample storage device 800 is not limited to this. As an alternative implementation scheme, at least one of the second consumable supply device 600, the first reagent storage component 1011, and the second reagent storage component 1012 can also be arranged on the second side of the second consumable conveying component 920. For example, the second consumable supply device 600 and / or the second reagent storage component 1012 can be arranged on the second side of the second consumable conveying component 920.

[0208] As an embodiment, at least part of the second consumables supply device 600, the first reagent storage assembly 1011, the second reagent storage assembly 1012, and the sample storage device 800 are sequentially arranged side by side along the first horizontal direction X, that is, the first consumables conveying assembly 910 extends from the side of the second consumables supply device 600, passes by the side of the first reagent storage assembly 1011, the side of the second reagent storage assembly 1012, and the side of the sample storage device 800. In this embodiment, the reagent area is arranged between the consumables area and the sample area. On the one hand, it is convenient to first distribute the reagents and then distribute the samples, so that the consumables are first transported to the reagent area for reagent distribution without passing through the sample area. After the sample distribution is completed, the consumables no longer pass through the reagent area, which helps to prevent the sample from contaminating the reagent area.

[0209] Of course, in specific applications, the side-by-side arrangement of the second consumable supply device 600, the first reagent storage component 1011, the second reagent storage component 1012, and the sample storage device 800 is not limited to the above-mentioned scheme. For example, the following alternative implementation scheme may also be adopted: at least part of the second consumable supply device 600, the second reagent storage component 1012, the first reagent storage component 1011, and the sample storage device 800 are sequentially arranged side by side along the first horizontal direction X; or, at least part of the second consumable supply device 600, the first reagent storage component 1011, the sample storage device 800, and the second reagent storage component 1012 are sequentially arranged side by side along the first horizontal direction X; or, at least part of the second consumable supply device 600, the second reagent storage component 1012, the sample storage device 800, and the first reagent storage component 1011 are sequentially arranged side by side along the first horizontal direction X; or, at least part of the second consumable supply device 600, the sample storage device 800, the second reagent storage assembly 1012, and the first reagent storage assembly 1011 are sequentially arranged side by side along the first horizontal direction X; or, the first reagent storage assembly 1011, the second reagent storage assembly 1012, the second consumable supply device 600, and the sample storage device 800 are sequentially arranged side by side along the first horizontal direction X; or, the second reagent storage assembly 1012, the first reagent storage assembly 1011, the second consumable supply device 600, and the sample storage device 800 are sequentially arranged side by side along the first horizontal direction X; or, the first reagent storage assembly 1011, the second consumable supply device 600, the second reagent storage assembly 1012, and the sample storage device 800 are sequentially arranged side by side along the first horizontal direction X; or, the second reagent storage assembly 1012, the second consumable supply device 600, the first reagent storage assembly 1011, and the sample storage device 800 are sequentially arranged side by side along the second horizontal direction Y.

[0210] As an embodiment, the sample storage device 800 , the second reagent storage component 1012 , the first reagent storage component 1011 , the second consumables supply device 600 , the amplification device 300 and the nucleic acid extraction device 200 are distributed around three sides of the first scheduling device 900 .

[0211] In one embodiment, the sample storage device 800, the second reagent storage assembly 1012, the first reagent storage assembly 1011, the second consumable supply device 600, the amplification device 300, and the nucleic acid extraction device 200 are arranged in a U-shape on three sides of the first scheduling device 900. Specifically, the sample storage device 800, the second reagent storage assembly 1012, the first reagent storage assembly 1011, and the second consumable supply device 600 are arranged side by side along the first horizontal direction X, the amplification device 300 and the nucleic acid extraction device 200 are arranged along the first horizontal direction X, the sample storage device 800, the second reagent storage assembly 1012, and the first reagent storage assembly 1011 are located on a first side of the first consumable transport assembly 910, the nucleic acid extraction device 200 and a portion of the amplification device 300 are located on a second side of the second consumable transport assembly 920, the second consumable supply device 600 extends from one side of the first reagent storage assembly 1011 toward the amplification device 300, and a portion of the amplification device 300 extends toward the second consumable supply device 600.

[0212] As an embodiment, the first consumables supply device 500 is provided below the second consumables supply device 600, and the first consumables supply device 500 extends from below the second consumables supply device 600 to below the reagent storage device 101. In this embodiment, the longitudinal space of the sample analyzer 10, i.e., the upper and lower spaces, is fully utilized, and the modules that occupy a large space, such as the nucleic acid extraction container 20, the amplification reaction container 30, and the reagents, are designed vertically, thereby facilitating further reduction in the horizontal space occupied by the sample analyzer 10. In addition, since the first consumables supply device 500, the second consumables supply device 600, the reagent storage device 101, and the sample storage device 800 are located on the same side of the sample analyzer 10, it is convenient for an operator or an operating robot to perform loading operations of the nucleic acid extraction container 20, the amplification reaction container 30, the first type of reagent, the second type of reagent, and the sample on the same side of the sample analyzer 10.

[0213] As an embodiment, the first consumables supply device 500 extends from directly below the second consumables supply device 600 to directly below the first reagent storage assembly 1011 and directly below the second reagent storage assembly 1012 .

[0214] As an embodiment, the sample analyzer 10 has an upper space and a lower space. The second consumables supply device 600, the first reagent storage assembly 1011, the second reagent storage assembly 1012, the first consumables transport assembly 910, the second consumables transport assembly 920, the nucleic acid extraction device 200, and the amplification device 300 are located in the upper space, and the first consumables supply device 500 is located in the lower space. In this embodiment, the nucleic acid extraction container 20 is stored in the lower space, while other consumables are stored and workstations are located in the upper space. This helps shorten the consumables scheduling path and makes the robot structure simpler, thereby reducing the horizontal footprint of the entire sample analyzer 10 and increasing the efficiency of consumables supply.

[0215] As an embodiment, the sample analyzer 10 also includes a housing assembly 107, which is divided into a first chamber 1071 and a second chamber 1072 along a first horizontal direction X. The second consumable supply device 600 and the reagent storage device 101 are distributed along the first horizontal direction X in the first chamber 1071, and the sample storage device 800 is located in the second chamber 1072; the reagent dispensing device 102 includes a reagent needle 1021, and the first chamber 1071 is provided with a first opening for the reagent needle 1021 to enter and exit; the sample dispensing device 100 includes a sample needle, and the second chamber 1072 is provided with a second opening for the sample needle to enter and exit. The first chamber 1071 forms a consumable area and a reagent area, and the second chamber 1072 forms a sample area. The first chamber 1071 and the second compartment are isolated from each other. In this embodiment, the sample is stored separately in a chamber, which helps to prevent the sample from contaminating the reagents and consumables. The reagents and the amplification reaction container 30 share a chamber, which helps reduce the number of chambers, thereby reducing the cost and complexity of the sample analyzer 10. Of course, in specific applications, as an alternative embodiment, the second consumables supply device 600 and the reagent storage device 101 can also be separately provided in two independent chambers.

[0216] As an embodiment, the distance from the first transfer position 9103 to the second opening is smaller than the distance to the first opening.

[0217] As an embodiment, at least part of the amplification device 300 and the nucleic acid extraction device 200 are distributed side by side along the first horizontal direction X on the second side of the second consumable material conveying assembly 920, that is, the second consumable material conveying assembly 920 extends from the side of the amplification device 300 to the side of the nucleic acid extraction device 200.

[0218] As an embodiment, the distance between the sample storage device 800 and the nucleic acid extraction device 200 is shorter than the distance to the amplification device 300. This helps shorten the travel time between the nucleic acid extraction container 200 and the nucleic acid extraction container 200 after sample distribution. Of course, in specific applications, as an alternative embodiment, the positions of the nucleic acid extraction device 200 and the amplification device 300 can also be swapped.

[0219] As an embodiment, at least part of the sample storage device 800 and at least part of the nucleic acid extraction device 200 are distributed on opposite sides of the first scheduling device 900, that is, the orthographic projection of the sample storage device 800 on any vertical plane parallel to the first horizontal direction X at least partially overlaps with the orthographic projection of the nucleic acid extraction device 200 on the vertical plane.

[0220] As an embodiment, the distance from the second consumables supply device 600 to the amplification device 300 is shorter than the distance from the second consumables supply device 600 to the nucleic acid extraction device 200 .

[0221] As an embodiment, at least part of the second consumable supply device 600 and at least part of the amplification device 300 are distributed on opposite sides of the first scheduling device 900, that is, the orthographic projection of the second consumable supply device 600 on any vertical plane parallel to the first horizontal direction X at least partially overlaps with the orthographic projection of the amplification device 300 on the vertical plane.

[0222] In one embodiment, the first reagent dispensing assembly and the second reagent dispensing assembly are the same reagent dispensing assembly, which includes a reagent needle 1021, a first lifting mechanism 1022, and a first horizontal movement mechanism 1023. The reagent needle 1021 is used to draw the first type of reagent from the first reagent storage assembly 1011 and dispense it into the nucleic acid extraction container 20, and to draw the second type of reagent from the second reagent storage assembly 1012 and dispense it into the amplification reaction container 30. The output end of the first lifting mechanism 1022 is connected to the reagent needle 1021 to drive the reagent needle 1021 up and down. The output end of the first horizontal movement mechanism 1023 is connected to the first lifting mechanism 1022 to drive the first lifting mechanism 1022 to drive the reagent needle 1021 to move horizontally. The first lifting mechanism 1022 can drive the reagent needle 1021 to perform one-dimensional linear motion in the vertical direction (i.e., up and down motion). The first horizontal movement mechanism 1023 can drive the first lifting mechanism 1022 to cause the reagent needle 1021 to perform two-dimensional horizontal movement (i.e., left-right movement and back-and-forth movement) or one-dimensional horizontal movement (i.e., left-right movement or back-and-forth movement) along the horizontal direction. In this embodiment, the first and second type reagents are dispensed using the same reagent needle 1021, which helps simplify the structure of the reagent dispensing device 102 and reduce the cost of the reagent dispensing device 102.

[0223] As an embodiment, the first lifting mechanism 1022 is used to output one-dimensional vertical linear motion, which may include a guide rail, a motor, a slider slidingly engaged with the guide rail, and a transmission mechanism connected between the motor and the slider.

[0224] As an embodiment, the first horizontal moving mechanism 1023 is used to output two-dimensional horizontal linear motion, which may include a guide rail, a motor, a slider slidingly engaged with the guide rail, and a transmission mechanism connected between the motor and the slider in one horizontal dimension, as well as a guide rail, a motor, a slider slidingly engaged with the guide rail, and a transmission mechanism connected between the motor and the slider in another horizontal dimension.

[0225] As an embodiment, the sample analyzer 10 further includes a fourth scheduling device 105, which is used to transfer the amplification reaction container 30 from the second consumables supply device 600 to the second consumables transport assembly 920. The fourth scheduling device 105 includes a first clamping device 1051 and a second lifting mechanism 1052. The first clamping device 1051 is used to clamp and release the amplification reaction container 30. The output end of the second lifting mechanism 1052 is connected to the first clamping device 1051 to at least drive the first clamping device 1051 to move up and down. The output end of the first horizontal movement mechanism 1023 is also connected to the second lifting mechanism 1052 to drive the second lifting mechanism 1052 to drive the first clamping device 1051 to move horizontally. The second lifting mechanism 1052 can drive the first clamping device 1051 to perform one-dimensional linear motion in the vertical direction (i.e., up and down motion). In this embodiment, the fourth scheduling device 105 used to transfer the amplification reaction container 30 from the second consumable supply device 600 to the second consumable conveying assembly 920 shares the first horizontal moving mechanism 1023 with the reagent dispensing device 102. This can save one horizontal moving mechanism, thereby simplifying the scheduling network of the sample analyzer 10 and reducing the cost of the sample analyzer 10.

[0226] As an embodiment, the scheduling of the amplification reaction container 30, the allocation of the first type of reagents, and the allocation of the second type of reagents are executed in the following order: the first horizontal moving mechanism 1023 drives the first clamping device 1051 and the reagent needle 1021 to move horizontally so that the first clamping device 1051 is above the amplification reaction container 30 located on the second consumables supply device 600, the second lifting mechanism 1052 drives the first clamping device 1051 to descend, the first clamping device 1051 grabs the amplification reaction container 30 from the second consumables supply device 600, the second lifting mechanism 1052 drives the first clamping device 1051 to drive the amplification reaction container 30 to rise, and the second horizontal moving mechanism drives the first clamping device 1051 and the reagent needle 1021 to move horizontally so that the reagent The reagent needle 1021 moves to the top of the first type of reagent, the first lifting mechanism 1022 drives the reagent needle 1021 to descend, and the reagent needle 1021 absorbs the first type of reagent; the first lifting mechanism 1022 drives the reagent needle 1021 to rise; the second horizontal moving mechanism and the first lifting mechanism 1022 repeat the above actions until the absorption of the first type of reagent is completed; the second horizontal moving mechanism drives the first clamping device 1051 and the reagent needle 1021 to move horizontally so that the reagent needle 1021 moves to the top of the first movable seat 912, the first lifting mechanism 1022 drives the reagent needle 1021 to descend, and the reagent needle 1021 injects at least part of the absorbed first type of reagent into the nucleic acid extraction container 20 located on the first movable seat 912; the first lifting mechanism 1022 Drive the reagent needle 1021 to rise; the second horizontal moving mechanism drives the first clamping device 1051 and the reagent needle 1021 to move horizontally so that the reagent needle 1021 moves to above the cleaning position, and the first lifting mechanism 1022 drives the reagent needle 1021 to descend, and the reagent needle 1021 is cleaned; the first lifting mechanism 1022 drives the reagent needle 1021 to rise; the second horizontal moving mechanism drives the first clamping device 1051 and the reagent needle 1021 to move horizontally so that the reagent needle 1021 moves to above the second type of reagent, and the first lifting mechanism 1022 drives the reagent needle 1021 to descend, and the reagent needle 1021 absorbs the second type of reagent; the first lifting mechanism 1022 drives the reagent needle 1021 to rise; the second horizontal moving mechanism drives the first clamping device 1051 and the reagent needle 1021 to move horizontally so that the reagent needle 1021 moves to above the second type of reagent. 051 and the reagent needle 1021 move horizontally to move the first clamping device 1051 to above the second movable seat 922; the second lifting mechanism 1052 drives the first clamping device 1051 to descend, the second clamping device 1081 releases the clamped amplification reaction container 30 on the second movable seat 922, and the second lifting mechanism 1052 drives the first clamping device 1051 to rise; the second horizontal moving mechanism drives the first clamping device 1051 and the reagent needle 1021 to move horizontally to move the reagent needle 1021 to above the second movable seat 922; the first lifting mechanism 1022 drives the reagent needle 1021 to descend, and the reagent needle 1021 injects at least part of the absorbed second type of reagent into the amplification reaction container 30 located on the second movable seat 922.Of course, in a specific application, as an alternative implementation scheme, the first type of reagent may be dispensed first, and then the amplification reaction container 30 may be grabbed and the second type of reagent may be dispensed.

[0227] As an embodiment, the first reagent storage component 1011 is also used to store the reconstituted reagent, and the reagent needle 1021 is also used to draw the reconstituted reagent from the first reagent storage component 1011 and dispense it into the second type of reagent in the second reagent storage component 1012 .

[0228] As an embodiment, the second consumables supply device 600 is also used to provide a container cover 40, which is used to cover and seal the amplification reaction container 30 after the pipetting device 700 transfers the nucleic acid extract from the nucleic acid extraction container 20 to the amplification reaction container 30. The sample analyzer 10 also includes a cover removal device 108, which includes a second clamping device 1081 and a third lifting mechanism. The second clamping device 1081 is used to clamp the container cover 40 from the second consumables supply device 600 and to release the clamped container cover 40 to the second consumables conveying assembly 920. The third lifting mechanism is used to drive the second clamping device 1081 to move up and down. The output end of the first horizontal moving mechanism 1023 is also connected to the third lifting mechanism to drive the third lifting mechanism to drive the second clamping device 1081 to move horizontally. The third lifting mechanism and the second lifting mechanism 1052 can be the same mechanism or two mechanisms that can be lifted and lowered independently of each other.

[0229] As an embodiment, the sample analyzer 10 also includes a capping device 1000, which is used to cover the container cover 40 on the second consumable transport component 920 on the amplification reaction container 30 to seal the amplification reaction container 30 after the pipetting device 700 transfers the nucleic acid extract in the nucleic acid extraction container 20 to the amplification reaction container 30 provided by the second consumable supply device 600 and loaded with at least the second type of reagent, nucleic acid extract and silicone oil.

[0230] As an embodiment, the second consumable material supply device 600 is used to place the container cover 40 to achieve loading of the container cover 40 .

[0231] As an embodiment, a fourth receiving groove 9223 for placing the container cover 40 is further provided on the top of the second movable seat 922 .

[0232] As an embodiment, the first consumable material transport assembly 910 has a first reagent dispensing position 9101, a sample loading position 9102, and a first transfer position 9103 distributed along the first horizontal direction X. The first consumable material transport assembly 910 is at least used to carry the nucleic acid extraction container 20 and move it to the first reagent dispensing position 9101, the sample loading position 9102, and the first transfer position 9103 in sequence; the first reagent dispensing assembly is used to draw at least part of the first type of reagent from the first reagent storage assembly 1011 and dispense it into the nucleic acid extraction container 20 located at the first reagent dispensing position 9101; the sample dispensing device 100 is used to draw at least part of the sample from the sample container and dispense it into the nucleic acid extraction container 20 located at the sample loading position 9102; the third scheduling device 104 is used to dispatch the nucleic acid extraction container 20 located at the first transfer position 9103 and loaded with the sample and the first type of reagent to the nucleic acid extraction device 200. In this embodiment, the first reagent dispensing position 9101, the sample loading position 9102, and the first transfer position 9103 are all located in the first consumable material transport assembly 910. The first type of reagents and samples can be directly distributed in the nucleic acid extraction container 20 of the first movable seat 912, without the need to remove the nucleic acid extraction container 20 from the first movable seat 912 and dispatch it to other locations for the dispensing of the first type of reagents and samples, thereby simplifying the dispatching network of the nucleic acid extraction container 20.

[0233] As an embodiment, the nucleic acid extraction device 200 extracts nucleic acid from a liquid containing at least a sample, including: lysing the liquid containing at least the sample and performing post-lysis processing.

[0234] As an embodiment, the first type of reagents include magnetic bead reagents, lysis reagents and elution reagents. In this embodiment, the nucleic acid extraction device 200 extracts nucleic acid from the sample based on the magnetic bead method, which mainly includes lysis, washing and elution. In the lysis step, the cells in the sample are ruptured by the lysis reagent to release nucleic acids, and the released nucleic acids are adsorbed on the magnetic beads of the magnetic bead reagent. In the washing step, the cleaning liquid is used to remove unnecessary components in the sample, such as washing away various impurities such as proteins and lipids remaining on and between the magnetic beads. In the elution step, the nucleic acid is separated from the magnetic beads by the elution reagent, so that purified nucleic acid can be obtained. In some detection items, the washed liquid needs to be dried before elution.

[0235] As an embodiment, the nucleic acid extraction container 20 is formed with a reaction hole 21 and a first liquid storage hole 22, the reaction hole 21 is used to carry at least a liquid obtained by mixing the sample with a magnetic bead reagent, a lysis reagent and an elution reagent for nucleic acid extraction, and the first liquid storage hole 22 is used to store the elution reagent; when the nucleic acid extraction container 20 is located at the first reagent dispensing position 9101, the first reagent dispensing component draws at least part of the magnetic bead reagent and the lysis reagent from the first reagent storage component 1011 and dispenses them into the reaction hole 21, and draws at least part of the elution reagent from the first reagent storage component 1011 and dispenses them into the The nucleic acid extraction container 20 is located in the first liquid reservoir 22; the first consumable material transport assembly 910 is used to carry the nucleic acid extraction container 20 loaded with at least a magnetic bead reagent, a lysis reagent, and an elution reagent from the first reagent dispensing position 9101 to the sample loading position 9102; the third scheduling device 104 is used to dispatch the nucleic acid extraction container 20 located at the first transfer position 9103 and loaded with at least a sample and a magnetic bead reagent, a lysis reagent, and an elution reagent to the nucleic acid extraction device 200; the nucleic acid extraction device 200 is also used to draw at least a portion of the elution reagent from the first liquid reservoir 22 and dispense it into the reaction well 21 during the nucleic acid extraction process. In this embodiment, by providing the first liquid reservoir 22 in the nucleic acid extraction container 20 to buffer the elution reagent, the reagent dispensing device 102 can dispense all of the first type of reagent into the nucleic acid extraction container 20 at once, avoiding the situation where the nucleic acid extraction container 20 returns to the reagent area to dispense the elution reagent after adding the sample, lysing, and washing, thereby preventing sample contamination of the reagent area and improving sample detection efficiency.

[0236] As an embodiment, the first reagent storage component 1011 is also used to store silicone oil; the nucleic acid extraction container 20 is also formed with a second liquid storage hole 23, and the second liquid storage hole 23 is used to store silicone oil; when the nucleic acid extraction container 20 is located at the first reagent dispensing position 9101, the first reagent dispensing component is also used to draw at least part of the silicone oil from the first reagent storage component 1011 and inject it into the second liquid storage hole 23; the first consumables conveying component 910 is used to carry the nucleic acid extraction container 20 loaded with at least magnetic bead reagent, lysis reagent, elution reagent, and silicone oil from the first reagent dispensing position 9101 to the sample loading position 9102; the third scheduling device 104 is used to schedule the nucleic acid extraction container 20 located at the first transfer position 9103 and loaded with at least a sample and magnetic bead reagent, lysis reagent, elution reagent, and silicone oil to the nucleic acid extraction device 200; the pipetting device 700 is also used to draw at least part of the silicone oil from the second liquid storage hole 23 and inject it into the amplification reaction container 30 loaded with nucleic acid extract. Silicone oil is primarily used to prevent volatilization of the nucleic acid extract during the amplification reaction. In this embodiment, by providing a second reservoir 23 in the nucleic acid extraction container 20 to buffer the silicone oil, the reagent dispensing device 102 can distribute the reagents used for nucleic acid extraction and amplification reactions to the nucleic acid extraction container 20 and the amplification reaction container 30 at once. This prevents the reagents from returning to the reagent area for distribution during the nucleic acid extraction and amplification processes, thereby preventing sample contamination of the reagent area and improving sample detection efficiency.

[0237] As one embodiment, the second consumable material transport assembly 920 has a second reagent dispensing position 9201, a first liquid injection position 9202, and a second transfer position 9203 distributed along a first horizontal direction X. The second consumable material transport assembly 920 is at least used to carry the amplification reaction container 30 from the second reagent dispensing position 9201 to the first liquid injection position 9202 and the second transfer position 9203 in sequence. The second reagent dispensing assembly is used to draw at least a portion of the second type of reagent from the second reagent storage assembly 1012 and dispense it into the amplification reaction container 30 located at the second reagent dispensing position 9201. The pipetting device 700 is used to draw at least a portion of the nucleic acid extract from the nucleic acid extraction container 20 and dispense it into the amplification reaction container 30 located at the first liquid injection position 9202. The sample analyzer 10 also includes a fifth scheduling device 106, which is used to dispatch the amplification reaction container 30 located at the second transfer position 9203 and loaded with the nucleic acid extract and the second type of reagent to the amplification device 300. In this embodiment, the second reagent dispensing position 9201, the first liquid injection position 9202 and the second transfer position 9203 are all located in the second consumable material delivery assembly 920. The second type of reagent and nucleic acid extract can be directly distributed into the amplification reaction container 30 of the second movable seat 922.

[0238] As an embodiment, the second consumable material transport assembly 920 also has a third transfer position 9204 and a first liquid aspiration position 9205 distributed along the first horizontal direction X; the sample analyzer 10 also includes a third scheduling device 104 and a first magnetic attraction assembly 1001, the third scheduling device 104 is used to schedule the nucleic acid extraction container 20 loaded with nucleic acid extract from the nucleic acid extraction device 200 to the third transfer position 9204; the second consumable material transport assembly 920 is also used to carry the nucleic acid extraction container 20 loaded with nucleic acid extract from the third transfer position 9204 to the first liquid aspiration position 9205; the first magnetic attraction assembly 1001 is arranged next to the first liquid aspiration position 9205, so as to perform magnetic adsorption on the nucleic acid extract in the nucleic acid extraction container 20 located at the first liquid aspiration position 9205; the pipetting device 700 is used to absorb at least part of the nucleic acid extract from the nucleic acid extraction container 20 located at the first liquid aspiration position 9205 and inject it into the amplification reaction container 30 located at the first liquid injection position 9202. In this embodiment, the aspiration and dispensing of the nucleic acid extract are both performed on the second consumable material conveying component 920, which helps to reduce the dispatching stroke of the nucleic acid extract.

[0239] As an embodiment, the second consumable material conveying assembly 920 includes a second guide rail 921, a second movable seat 922 and a second driving mechanism 923. The second guide rail 921 extends along the first horizontal direction X. The top of the second movable seat 922 is provided with a second accommodating groove 9221 for placing the amplification reaction container 30 and a third accommodating groove 9222 for placing the nucleic acid extraction container 20. The second driving mechanism 923 is used to drive the second movable seat 922 to perform linear motion along the second guide rail 921.

[0240] As an embodiment, the sample analyzer 10 further includes a controller 109 and a sixth scheduling device 1002, and the controller 109 is configured to perform the following control actions: controlling the sixth scheduling device 1002 to schedule the amplification reaction container 30 provided by the second consumables supply device 600 to the second reagent dispensing position 9201 and place the amplification reaction container 30 in the second receiving groove 9221 of the second movable seat 922; controlling the second reagent dispensing component to draw at least part of the second type of reagent from the second reagent storage component 1012 and dispense it into the second reagent dispensing position 9201 and the second reagent dispensing position 920 ...1; controlling the second reagent dispensing component to draw at least part of the second type of reagent from the second reagent dispensing component 1012 and dispense it into the second reagent dispensing position 9201 and the second reagent dispensing position 9201; controlling the second reagent dispensing component to draw at least part of the second type of reagent from the second reagent dispensing component 1012 and dispense it into the second reagent dispensing position 9201 and the second reagent dispensing position 9201; controlling the second reagent dispensing component to draw at least part of the second type of reagent from the second The amplification reaction container 30 of the amplification reaction container 30 in the position 9201 is controlled; the second driving mechanism 923 is controlled to drive the second movable seat 922 to move linearly along the second guide rail 921 so that the second movable seat 922 drives the amplification reaction container 30 loaded with the second type of reagent to move, and the third receiving groove 9222 of the second movable seat 922 moves to the third transfer position 9204; the third scheduling device 104 is controlled to schedule the nucleic acid extraction container 20 loaded with the nucleic acid extraction solution from the nucleic acid extraction device 200 to the third transfer position 9204 and place it in the third receiving groove 9222 of the second movable seat 92 ... The mechanism 923 drives the second movable seat 922 to move so as to drive the amplification reaction container 30 loaded with the second type of reagent and the nucleic acid extraction container 20 loaded with the nucleic acid extract to move, so that the nucleic acid extraction container 20 loaded with the nucleic acid extract moves to the first liquid aspiration position 9205, and the amplification reaction container 30 loaded with the second type of reagent moves to the first liquid injection position 9202; controls the pipetting device 700 to absorb at least part of the nucleic acid extract from the nucleic acid extraction container 20 located at the first liquid aspiration position 9205 and distributes it to the amplification reaction container 30 located at the first liquid injection position 9202; controls the third scheduling device 700 to control the amplification reaction container 30 to move the nucleic acid extract to the first liquid injection position 9202; and controls the third scheduling device 700 to control the amplification reaction container 30 to move the nucleic acid extract to the first liquid aspiration position 9205. 104 takes out the nucleic acid extraction container 20 placed in the third accommodating groove 9222 and located at the first liquid aspiration position 9205 from above the second movable seat 922 and dispatches it to the recovery position for disposal for recycling; controls the second driving mechanism 923 to drive the second movable seat 922 to move so as to drive the amplification reaction container 30 loaded with nucleic acid extract and second type reagent to move from the first liquid injection position 9202 to the second transfer position 9203; controls the fifth dispatching device 106 to transfer the amplification reaction container 30 located at the second transfer position 9203 and loaded with nucleic acid extract and second type reagent to the amplification device 300.

[0241] As an embodiment, the controller 109 is further configured to: control the second scheduling device 103 to schedule the nucleic acid extraction container 20 provided by the first consumables storage device to the first reagent dispensing position 9101, control the first reagent dispensing component to respectively absorb silicone oil, elution reagent, magnetic bead reagent and lysis reagent from the first reagent storage component 1011, control the first reagent dispensing component to dispense the absorbed magnetic bead reagent and lysis reagent into the reaction hole 21, dispense the absorbed elution reagent into the first liquid storage hole 22, and dispense the absorbed silicone oil into the second liquid storage hole 23, control the first consumables conveying component 910 to carry the silicone oil, elution reagent, magnetic bead reagent and lysis reagent from the first reagent storage component 1011, and control the first reagent dispensing component to dispense the absorbed magnetic bead reagent and lysis reagent into the reaction hole 21, dispense the absorbed elution reagent into the first liquid storage hole 22, and dispense the absorbed silicone oil into the second liquid storage hole 23. The nucleic acid extraction container 20 containing the elution reagent, magnetic bead reagent and lysis reagent moves to the sample loading position 9102, controls the sample dispensing device 100 to distribute at least part of the sample sucked into the nucleic acid extraction container 20 located at the sample loading position 9102, controls the first consumables conveying component 910 to carry the nucleic acid extraction container 20 loaded with the sample and silicone oil, elution reagent, magnetic bead reagent and lysis reagent to the first transfer position 9103, controls the third scheduling device 104 to transfer the nucleic acid extraction container 20 located at the first transfer position 9103 and loaded with the sample and silicone oil, elution reagent, magnetic bead reagent and lysis reagent to the nucleic acid extraction device 200, and controls The nucleic acid extraction device 200 extracts nucleic acid from the liquid containing at least a sample, a magnetic bead reagent, a lysis reagent, and an elution reagent in the nucleic acid extraction container 20 to obtain a nucleic acid extract solution, controls the pipetting device 700 to draw at least part of the nucleic acid extract solution from the reaction hole 21 of the nucleic acid extraction container 20 and injects it into the amplification reaction container 30 provided by the second consumables supply device 600, controls the pipetting device 700 to draw silicone oil from the second liquid storage hole 23 and injects it into the amplification reaction container 30 loaded with the nucleic acid extract solution; controls the capping device 1000 to cover the container cover 40 on the amplification reaction container 30; controls the third scheduling device 104 to put the nucleic acid extract solution into ... The acid extraction container 20 is dispatched to the recovery position for recycling; the second consumable material conveying component 920 is controlled to drive the amplification reaction container 30 loaded with the nucleic acid extract, the second type of reagent, and the silicone oil to move from the first filling position 9202 to the second transfer position 9203; the fifth scheduling device 106 is controlled to transfer the amplification reaction container 30 located at the second transfer position 9203 and loaded with the nucleic acid extract, the second type of reagent, and the silicone oil to the amplification device 300; the amplification device 300 is controlled to amplify the liquid containing the nucleic acid extract and the second type of reagent in the amplification reaction container 30 to obtain the liquid to be tested, and the detection device 400 is controlled to detect the liquid to be tested.

[0242] As an embodiment, the first consumables supply device 500 is also used to store pipette tips; the nucleic acid extraction container 20 is formed with a reaction well 21 and at least one pipette tip hole. The reaction well 21 is used to carry at least a liquid obtained by mixing the sample and the first type of reagent for nucleic acid extraction, and the pipette tip hole is used to accommodate the pipette tip; the pipette device 700 is used to draw at least a portion of the nucleic acid extraction liquid from the nucleic acid extraction container 20 through the pipette tip and dispense it into the amplification reaction container 30. After a pipette tip completes the corresponding pipetting action in a test item, it is released to the recovery position together with the nucleic acid extraction container 20 for recycling, thereby eliminating the cleaning step and improving the detection efficiency. In this embodiment, the pipette tip is directly placed in the nucleic acid extraction container 20. On the one hand, it is no longer necessary to set up a separate pipette tip storage bin and dispatching mechanism in the sample analyzer 10; on the other hand, it is beneficial to shorten the dispatching stroke of the pipette tip when using the pipette tip for pipetting, thereby improving the pipetting efficiency. The pipetting device 700 transfers liquid from the nucleic acid extraction container 20 via a pipetting tip, thereby eliminating the need for cleaning the pipetting device 700 .

[0243] As an embodiment, the nucleic acid extraction device 200 is further used to perform pipetting through at least one pipette tip on the nucleic acid extraction container 20 .

[0244] As an embodiment, the above-mentioned nucleic acid extraction device 200 performs pipetting through at least one pipette tip on the nucleic acid extraction container 20, including: the nucleic acid extraction device 200 aspirates liquid from the reaction hole 21 through the pipette tip on the nucleic acid extraction container 20 and dispenses it into the waste liquid hole 26; the nucleic acid extraction device 200 aspirates elution reagent from the first liquid storage hole 22 through the pipette tip on the nucleic acid extraction container 20 and dispenses it into the reaction hole 21. In this embodiment, the nucleic acid extraction device 200 can aspirate waste liquid and / or dispense elution reagent through the pipette tip.

[0245] In one embodiment, the nucleic acid extraction container 20 is formed with two pipette tip holes, namely a first pipette tip hole 24 and a second pipette tip hole 25. The first pipette tip hole 24 is used to hold a first pipette tip 50, and the second pipette tip hole 25 is used to hold a second pipette tip 60. The volume of the first pipette tip 50 is larger than that of the second pipette tip. The nucleic acid extraction device 200 includes a first pipette component and a second pipette component. The first pipette component is used to aspirate liquid from the reaction well 21 via the first pipette tip 50 on the nucleic acid extraction container 20 and dispense it into the waste liquid well 26. The second pipette component is used to aspirate elution reagent from the first liquid storage well 22 via the second pipette tip 60 on the nucleic acid extraction container 20 and dispense it into the reaction well 21. The pipette device 700 aspirates the nucleic acid extraction liquid from the nucleic acid extraction container 20 via the second pipette tip 60 and dispenses it into the amplification reaction container 30.

[0246] As an embodiment, the first pipetting component includes a first tip connecting component and a first suction and discharge power component; the first tip connecting component is used to be detachably connected to the first pipetting tip 50, so as to aspirate and inject liquid through the first pipetting tip 50 under the action of the power provided by the first suction and discharge power component; the second pipetting component includes a second tip connecting component and a second suction and discharge power component, and the second tip connecting component is used to be detachably connected to the second pipetting tip 60, so as to aspirate and inject liquid through the second pipetting tip 60 under the action of the power provided by the second suction and discharge power component.

[0247] As an embodiment, the first pipetting component also includes a first moving power component, which is used to drive the first tip connecting component to move, so that the first tip connecting component moves to the top of the first tip hole 24, connects the first tip connecting component to the first pipetting tip 50, and drives the first pipetting tip 50 to move and insert into the reaction hole 21; the first suction and discharge power component is used to provide driving force for the first pipetting tip 50 to perform the suction action after the first pipetting tip 50 is inserted into the reaction hole 21.

[0248] As an embodiment, the second pipetting component also includes a second moving power component, which is used to drive the second tip connecting component to move, so that the second tip connecting component moves to above the second tip hole 25, connects the second tip connecting component to the second pipetting tip 60, drives the second pipetting tip 60 to move to the elution reagent aspiration position, and drives the second pipetting tip 60 to move and insert into the reaction hole 21; the second suction and discharge power component is used to provide driving force for the second pipetting tip 60 to perform the aspiration action after the second pipetting tip 60 moves to the elution reagent aspiration position, and provides driving force for the second pipetting tip 60 to perform the dispensing of elution reagent after the second pipetting tip 60 is inserted into the reaction hole 21.

[0249] As an embodiment, the nucleic acid extraction container 20 is further formed with a waste liquid hole 26, and the first pipetting member is also used to discharge the liquid sucked from the reaction hole 21 to the waste liquid hole 26, which can help shorten the waste liquid discharge path during the nucleic acid extraction process.

[0250] In one embodiment, the nucleic acid extraction device 200 has at least two workstations, each of which is used to carry a nucleic acid extraction container 20 and perform a processing action. The at least two workstations are vertically distributed one above the other. The processing action includes at least one of an incubation action, a magnetic adsorption action, and a liquid aspiration action. In this embodiment, the at least two workstations in the nucleic acid extraction device 200 are distributed vertically. This helps reduce the horizontal space occupied by the nucleic acid extraction device 200, thereby facilitating the miniaturization of the sample analyzer 10.

[0251] In one embodiment, a nucleic acid extraction device 200 includes a first functional component 210, a second functional component 220, and a dispatching component. The second functional component 220 is located below or above the first functional component 210. The dispatching component is used to dispatch the nucleic acid extraction container 20 between the second functional component 220 and the first functional component 210. The first functional component 210 is used to carry the nucleic acid extraction container 20 for performing a first functional action, and the second functional component 220 is used to carry the nucleic acid extraction container 20 for performing a second functional action. The second functional action includes at least an incubation action, and the first functional action includes at least a magnetic adsorption action and a liquid aspiration action. In this embodiment, by disposing the second functional component 220 for carrying the nucleic acid extraction container 20 for performing the incubation action below or above the first functional component 210 for carrying the nucleic acid extraction container 20 for performing the magnetic adsorption action and the liquid aspiration action in the nucleic acid extraction device 200, that is, the second functional component 220 and the first functional component 210 are arranged in a vertical direction, thereby reducing the horizontal space occupied by the nucleic acid extraction device 200, thereby facilitating a miniaturized design of the sample analyzer 10. The scheduling component and the third scheduling device 104 can be the same component or two different components.

[0252] As an implementation manner, the second functional component 220 is disposed below the first functional component 210 .

[0253] As an embodiment, the first functional action includes at least one of a liquid suction action, a liquid injection action, and a magnetic adsorption action.

[0254] As an embodiment, the second functional action includes at least one of an incubation action and a mixing action.

[0255] As an embodiment, the nucleic acid extraction device 200 is divided into two major parts, an upper part and a lower part. Among them, the upper part of the nucleic acid extraction device 200 is mainly used to realize functions such as injection of cleaning liquid, magnetic adsorption, and waste liquid suction and discharge. The upper part of the nucleic acid extraction device 200 is mainly used to realize functions such as incubation and mixing. In this embodiment, the key functional modules are designed in an upper and lower layout, and components with similar functions are integrated into a functional module design. For example, as an embodiment, the lower part completes the functions of lysis, incubation, mixing, nucleic acid capture, nucleic acid washing, and nucleic acid elution in nucleic acid extraction; while the upper part realizes functions such as liquid injection, magnetic separation, and waste liquid suction and discharge. Then, by designing one or more manipulator functional modules, the nucleic acid extraction container 20 is grabbed and transferred between the upper and lower functional components and various workstations, thereby completing the complete nucleic acid extraction function. In this embodiment, all workstations that require incubation are integrated into one functional component, and all workstations that require suction and injection are integrated into another functional component. The two functional components are then distributed up and down, and the nucleic acid extraction container 20 is transferred back and forth up and down. In this way, parts with similar functions are integrated into one functional component, which can reduce the difficulty of designing and manufacturing the nucleic acid extraction device 200 while reducing the horizontal area.

[0256] As an embodiment, the upper portion of the nucleic acid extraction device 200 is provided with four workstations, wherein workstation 1 is used to adsorb magnetic beads, remove waste liquid, and inject cleaning solution for samples after lysis. Workstation 2 is used to remove waste liquid and inject cleaning solution for samples after cleaning and incubation in cleaning zone 1. Workstation 3 is used to remove waste liquid for samples after cleaning and incubation in cleaning zone 2. Workstation 4 is used to remove waste liquid and inject elution reagent for samples after cleaning and incubation in cleaning zone 2.

[0257] As an embodiment, the lower part of the nucleic acid extraction device 200 is disc-shaped and divided into the following five areas: lysis area, cleaning area 1, cleaning area 2, drying area and elution area; each of which realizes its corresponding function; the nucleic acid extraction container 20 can be clamped by the scheduling component and placed in different areas to perform different functions.

[0258] In one embodiment, the scheduling component is used to: clamp the nucleic acid extraction container 20 from the lower second functional component 220 (i.e., the mixing and incubation module) to the four workstations of the upper first functional component 210, and to clamp the nucleic acid extraction container 20 from the four workstations of the upper first functional component 210 to the lower second functional component 220 for operation. In an alternative embodiment, the scheduling component can also be used to transfer the nucleic acid extraction container 20 between different workstations of the upper first functional component 210-110 and / or transfer the nucleic acid extraction container 20 between different areas of the lower second functional component 220.

[0259] As an implementation method, the scheduling component is a robot.

[0260] As an embodiment, the functional components of the upper part are divided into different stations to realize corresponding functions. The lower part is divided into different areas, and each area performs different functions, and then the nucleic acid extraction container 20 is grasped and transferred by the robot.

[0261] As an embodiment, the amplification device 300 can use methods for nucleic acid amplification processing such as polymerase chain reaction (PCR), loop mediated isothermal amplification (LAMP), isothermal and chimeric primer initiated nucleic acid amplification (ICAN), nuclear acid sequence-based amplification (NASBA), strand displacement amplification (SDA), ligase chain reaction (LCR), rolling circle amplification (RCA), etc.

[0262] In one embodiment, the detection device 400 is used to perform fluorescence detection on amplified nucleic acids. During the nucleic acid amplification and real-time fluorescence detection process, the signal of each nucleic acid amplification cycle is read to obtain a fluorescence amplification curve. Based on the information fed back by the detection device 400, the controller 109 generates the fluorescence amplification curve and obtains a qualitative result (negative or positive) based on the fluorescence amplification curve, or obtains a quantitative analysis result and the concentration of the analyte in the sample based on the calibration curve.

[0263] As an embodiment, the sample analyzer 10 is an integrated molecular diagnostic device for detecting RNA or DNA through nucleic acid extraction.

[0264] This embodiment optimizes the layout and consumables scheduling of the sample analyzer 10. This effectively reduces the horizontal dimensions of the sample analyzer 10, significantly reducing its footprint and thereby improving space utilization in molecular laboratories. Furthermore, it simplifies the scheduling network for the sample analyzer 10, thereby reducing the cost of the sample analyzer 10 and improving its detection efficiency.

[0265] Example 2:

[0266] 1 , 2 and 17 , the sample analyzer 10 provided in this embodiment differs from that in the first embodiment primarily in that the second consumables supply device 600, the reagent storage device 101, the sample storage device 800, the nucleic acid extraction device 200, the amplification device 300 and the first scheduling device 900 are distributed in a different manner, specifically as follows: in the first embodiment, the second consumables supply device 600, the reagent storage device 101, the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 are distributed in a U-shape around three sides of the first scheduling device 900; whereas in this embodiment, the second consumables supply device 600, the reagent storage device 101, the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 are divided into two rows and distributed on opposite sides of the first scheduling device 900.

[0267] Specifically, in this embodiment, the second consumables supply device 600, the reagent storage device 101, and the sample storage device 800 are distributed on the first side of the first consumables conveying assembly 910 along the first horizontal direction X; the amplification device 300 and the nucleic acid extraction device 200 are distributed on the second side of the second consumables conveying assembly 920 along the first horizontal direction X, that is, the second consumables supply device 600, the reagent storage device 101, the sample storage device 800, the amplification device 300 and the nucleic acid extraction device 200 are divided into two rows and distributed on opposite sides of the first scheduling device 900.

[0268] Except for the above differences, other parts of the sample analyzer 10 provided in this embodiment can refer to the first embodiment and will not be described in detail here.

[0269] Example 3:

[0270] 1 , 2 , 13 , 14 , and 18 , the sample analyzer 10 provided in this embodiment differs from the first embodiment primarily in the focus of protection, specifically as follows: in the first embodiment, protection is emphasized, with two consumables conveying lines for conveying nucleic acid extraction containers 20 and amplification reaction containers 30 arranged side by side in a scheduling area in the middle of the sample analyzer 10, and at least portions of the sample storage device 800 , nucleic acid extraction device 200 , and amplification device 300 arranged on opposite sides of the scheduling area; whereas, in the present embodiment, protection is emphasized, with at least one consumables conveying line for conveying nucleic acid extraction containers 20 and / or amplification reaction containers 30 arranged in the scheduling area in the middle of the sample analyzer 10, the second consumables supply device 600 and the sample storage device 800 arranged side by side and at least partially located on one side of the consumables conveying line, and at least portions of the nucleic acid extraction device 200 and at least portions of the amplification device 300 arranged on the other side of the consumables conveying line.

[0271] Specifically, the sample analyzer 10 provided in this embodiment includes a first consumables supply device 500, a second consumables supply device 600, a sample storage device 800, a sample distribution device 100, a nucleic acid extraction device 200, an amplification device 300, a detection device 400, a first scheduling device 900, and a pipetting device 700. The first consumables supply device 500 is used to provide at least a nucleic acid extraction container 20. The second consumables supply device 600 is used to provide at least an amplification reaction container 30. The first scheduling device 900 is used to carry the nucleic acid extraction container 20 and / or the amplification reaction container 30 for movement. The sample storage device 800 is used to store at least a sample container loaded with a sample. The sample distribution device 100 is used to draw at least a portion of the sample from the sample container provided by the sample storage device 800 and dispense it into the nucleic acid extraction container 20 provided by the first consumables supply device 500. The nucleic acid extraction device 200 is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container 20 to obtain a nucleic acid extract. The pipetting device 700 is used to aspirate at least a portion of the nucleic acid extract from the nucleic acid extraction container 20 and dispense it into the amplification reaction container 30 provided by the second consumables supply device 600. The amplification device 300 is used to amplify the liquid in the amplification reaction container 30, which contains at least the nucleic acid extract, to obtain a test liquid; the detection device 400 is used to detect the test liquid.

[0272] In one embodiment, the first scheduling device 900 includes at least one consumable transport assembly, which is used to carry the nucleic acid extraction container 20 and / or the amplification reaction container 30 along a trajectory at least partially parallel to the first horizontal direction X. One of the consumable transport assemblies has a first side and a second side arranged on opposite sides along the second horizontal direction Y. The second consumable supply device 600 and the sample storage device 800 are arranged side by side along the first horizontal direction X, with at least one of them at least partially located on the first side of the consumable transport assembly. At least a portion of the nucleic acid extraction device 200 and at least a portion of the amplification device 300 are arranged side by side along the first horizontal direction X on the second side of the consumable transport assembly. The second horizontal direction Y is substantially perpendicular to the first horizontal direction X. In this embodiment, the central scheduling area of ​​the sample analyzer 10 forms at least one consumable transport line for transporting the nucleic acid extraction container 20 and / or the amplification reaction container 30. The second consumables supply device 600, the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 are distributed on at least two opposite sides of the intermediate consumables conveying line. In this way, the second consumables supply device 600 and the sample storage device 800 are arranged side by side along the first horizontal direction X and at least one of them is located on one side of the intermediate consumables conveying line, and the nucleic acid extraction device 200 and the amplification device 300 are arranged side by side along the first horizontal direction X on the other side of the intermediate consumables conveying line. In this way, the size of the sample analyzer 10 in a single horizontal direction can be effectively reduced, and it is convenient for the operator or the operating robot to perform the loading of the amplification reaction container 30 and the sample on the same side of the sample analyzer 10.

[0273] As an embodiment, the orthographic projection of the consumable transport assembly on any vertical plane parallel to the first horizontal direction X and the orthographic projection of the nucleic acid extraction device 200 on the vertical plane at least partially overlap, and the orthographic projection of the consumable transport assembly on any vertical plane parallel to the first horizontal direction X and the orthographic projection of the sample storage device 800 on the vertical plane at least partially overlap.

[0274] As an embodiment, the orthographic projection of the consumable material transport assembly on any vertical plane parallel to the first horizontal direction X and the orthographic projection of the amplification device 300 on the vertical plane at least partially overlap.

[0275] As an embodiment, the orthographic projection of the consumables transport assembly on any vertical plane parallel to the first horizontal direction X and the orthographic projection of the sample storage device 800 on the vertical plane at least partially overlap.

[0276] As an embodiment, at least one consumable transport assembly includes a first consumable transport assembly 910 and a second consumable transport assembly 920, that is, the first scheduling device 900 includes a first consumable transport assembly 910 and a second consumable transport assembly 920, the first consumable transport assembly 910 has a first side and a second side arranged on opposite sides along the second horizontal direction Y, at least part of the second consumable supply device 600 and at least part of the sample storage device 800 are distributed side by side along the first horizontal direction X and at least part of at least one of the two is located on the first side of the first consumable transport assembly 910, at least part of the nucleic acid extraction device 200 and at least part of the amplification device 300 are distributed side by side along the first horizontal direction X and are both at least partially located on the second side of the first consumable transport assembly 910, and the second consumable transport assembly 920 is arranged along the second horizontal direction Y. The nucleic acid extraction device 200 and the amplification device 300 are on one side away from the first consumable material transport assembly 910. The first consumable material transport assembly 910 is at least used to carry the nucleic acid extraction container 20 for linear movement along the first horizontal direction X. The second consumable material transport assembly 920 is at least used to carry the amplification reaction container 30 for linear movement along the first horizontal direction X. The orthographic projection of at least one of the first consumable material transport assembly 910 and the second consumable material transport assembly on any vertical plane parallel to the first horizontal direction X at least partially overlaps with the orthographic projection of the nucleic acid extraction device 200 on the vertical plane. The orthographic projection of at least one of the first consumable material transport assembly 910 and the second consumable material transport assembly on any vertical plane parallel to the first horizontal direction X at least partially overlaps with the orthographic projection of the sample storage device 800 in the vertical plane. In this embodiment, the central dispatching area forms only one consumables conveyor line, which is used to transport nucleic acid extraction containers 20. Another consumables conveyor line, used to transport at least one amplification reaction container 30, is located on one side of the edge of the nucleic acid extraction device 200 and amplification device 300. In other words, the nucleic acid extraction device 200 and amplification device 300 are located between the two consumables conveyor lines. This arrangement also reduces the single horizontal dimension of the sample analyzer 10.

[0277] As an embodiment, the sample analyzer 10 further includes a reagent storage device 101 and a reagent dispensing device 102. The reagent storage device 101 is used to store reagents, and the reagent dispensing device 102 is used to draw reagents from the reagent storage device 101 and dispense them into the nucleic acid extraction container 20 and / or the amplification reaction container 30. The second consumable supply device 600, the reagent storage device 101, and the sample storage device 800 are arranged side by side along the first horizontal direction X on a first side of one of the consumable transport assemblies, away from the nucleic acid extraction device 200 and the amplification device 300. Specifically, the first consumable transport assembly 910 has a first side and a second side disposed oppositely along the second horizontal direction Y, and the second consumable transport assembly 920 has a first side and a second side disposed oppositely along the second horizontal direction Y. The second side of the first consumable transport assembly 910 faces the first side of the second consumable transport assembly 920. The nucleic acid extraction device 200 and the amplification device 300 are arranged side by side along the first horizontal direction X and are at least partially located between the second side of the first consumable transport assembly 910 and the first side of the second consumable transport assembly 920. The second consumables supply device 600 , the reagent storage device 101 and the sample storage device 800 are arranged side by side along the first horizontal direction X.

[0278] In addition to the above, other parts of the sample analyzer 10 provided in this embodiment can refer to the first and second embodiments and will not be described in detail here.

[0279] Example 4:

[0280] 1 , 2 , 13 , 14 , 18 and 19 , the difference between the sample analyzer 10 provided in this embodiment and those in Embodiment 1 and Embodiment 3 lies in the different distribution positions of the two consumables conveying lines, which are specifically reflected in the following: in Embodiment 1, the two consumables conveying lines are located between the functional modules; in Embodiment 3, at least the consumables conveying line for conveying the nucleic acid extraction container 20 is located between the functional modules, and at least the consumables conveying line for conveying the amplification reaction container 30 is located at an edge outside the functional modules; whereas in this embodiment, at least the consumables conveying line for conveying the amplification reaction container 30 is located between the functional modules, and at least the consumables conveying line for conveying the nucleic acid extraction container 20 is located at an edge outside the functional modules.

[0281] Specifically, in this embodiment, at least one consumable conveying assembly includes a first consumable conveying assembly 910 and a second consumable conveying assembly 920, the second consumable conveying assembly 920 has a first side and a second side arranged on opposite sides along the second horizontal direction Y, the second consumable supply device 600 and the sample storage device 800 are side by side along the first horizontal direction X and at least part of at least one of the two is located on the first side of the second consumable conveying assembly 920, at least part of the nucleic acid extraction device 200 and at least part of the amplification device 300 are distributed side by side along the first horizontal direction X on the second side of the second consumable conveying assembly 920, the first consumable conveying assembly 910 is arranged on the side of the second consumable supply device 600 and the sample storage device 800 away from the second consumable conveying assembly 920, the first consumable conveying assembly 910 is at least used to carry the nucleic acid extraction container 20 for linear motion along the first horizontal direction X, and the second consumable conveying assembly 920 is at least used to carry the amplification reaction container 30 for linear motion along the first horizontal direction X. In this embodiment, the central scheduling area forms only one consumables conveyor line, which is used to convey at least the amplification reaction vessels 30. Another consumables conveyor line, used to convey at least the nucleic acid extraction vessels 20, is located on one side of the edge of the second consumables supply device 600 and the sample storage device 800. That is, the second consumables supply device 600 and the sample storage device 800 are located between the two consumables conveyor lines. This arrangement also reduces the single horizontal dimension of the sample analyzer 10.

[0282] As an embodiment, the orthographic projection of at least one of the first consumable material transport assembly 910 and the second consumable material transport assembly on any vertical plane parallel to the first horizontal direction X at least partially overlaps with the orthographic projection of the nucleic acid extraction device 200 on the vertical plane, and the orthographic projection of at least one of the first consumable material transport assembly 910 and the second consumable material transport assembly on any vertical plane parallel to the first horizontal direction X at least partially overlaps with the orthographic projection of the sample storage device 800 on the vertical plane.

[0283] In addition to the above, other parts of the sample analyzer 10 provided in this embodiment can refer to the first to third embodiments and will not be described in detail here.

[0284] Embodiment 5:

[0285] 1 , 2 , 13 , 14 and 20 , the difference between the sample analyzer 10 provided in this embodiment and embodiments one to four lies mainly in the different ways in which the consumables conveying lines are set up, which is specifically reflected in that: in embodiments one to four, two consumables conveying lines are formed for conveying the nucleic acid extraction container 20 and the amplification reaction container 30 ; whereas in this embodiment, only one consumables conveying line is formed for conveying the nucleic acid extraction container 20 and the amplification reaction container 30 .

[0286] Specifically, in this embodiment, at least one consumable conveying assembly includes a third consumable conveying assembly 930, the third consumable conveying assembly 930 has a first side and a second side arranged on opposite sides along the second horizontal direction Y, the second consumable supply device 600 and the sample storage device 800 are side by side along the first horizontal direction X and at least part of at least one of the two is located on the first side of the third consumable conveying assembly 930, at least part of the nucleic acid extraction device 200 and at least part of the amplification device 300 are distributed side by side along the first horizontal direction X on the second side of the third consumable conveying assembly 930, and the third consumable conveying assembly 930 is used to carry the nucleic acid extraction container 20 and the amplification reaction container 30 for linear motion along a straight line trajectory parallel to the first horizontal direction X or for movement along a U-shaped trajectory partially parallel to the first horizontal direction X. In this embodiment, the intermediate scheduling area forms only one consumables conveying line, which is in the shape of a straight line or a U-shape and is used to convey both the amplification reaction container 30 and the nucleic acid extraction container 20. At least part of the second consumables supply device 600 and at least part of the sample storage device 800 are distributed side by side along the first horizontal direction X and are located on one side of the intermediate consumables conveying line. At least part of the nucleic acid extraction device 200 and at least part of the amplification device 300 are distributed side by side along the first horizontal direction X and are located on the other side of the intermediate consumables conveying line. The second consumables supply device 600, the sample storage device 800, the nucleic acid extraction device 200, and the amplification device 300 are distributed on at least the opposite side of the intermediate consumables conveying line. Using this arrangement, the purpose of reducing the single horizontal dimension of the sample analyzer 10 can also be achieved.

[0287] As an embodiment, the orthographic projection of the third consumable material transport assembly on any vertical plane parallel to the first horizontal direction X at least partially overlaps with the orthographic projection of the nucleic acid extraction device 200 on the vertical plane, and the orthographic projection of the third consumable material transport assembly on any vertical plane parallel to the first horizontal direction X at least partially overlaps with the orthographic projection of the sample storage device 800 on the vertical plane.

[0288] In addition to the above, other parts of the sample analyzer 10 provided in this embodiment can refer to the first to fourth embodiments and will not be described in detail here.

[0289] Example 6:

[0290] 1 , 2 , 13 , 14 and 21 , the difference between the sample analyzer 10 provided in this embodiment and embodiments one to five lies mainly in the different distribution of consumable conveying lines, which is specifically reflected in that: in embodiments one to five, at least one consumable conveying line is distributed between each functional module; whereas in this embodiment, both consumable conveying lines are distributed outside each functional module.

[0291] Specifically, the sample analyzer 10 provided in this embodiment includes a first consumables supply device 500, a second consumables supply device 600, a sample storage device 800, a sample distribution device 100, a nucleic acid extraction device 200, an amplification device 300, a detection device 400, a first scheduling device 900, and a pipetting device 700. The first consumables supply device 500 is used to provide at least a nucleic acid extraction container 20. The second consumables supply device 600 is used to provide at least an amplification reaction container 30. The first scheduling device 900 is used to carry the nucleic acid extraction container 20 and / or the amplification reaction container 30 for movement. The sample storage device 800 is used to store at least a sample container loaded with a sample. The sample distribution device 100 is used to draw at least a portion of the sample from the sample container provided by the sample storage device 800 and dispense it into the nucleic acid extraction container 20 provided by the first consumables supply device 500. The nucleic acid extraction device 200 is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container 20 to obtain a nucleic acid extract. The pipetting device 700 is used to aspirate at least a portion of the nucleic acid extract from the nucleic acid extraction container 20 and dispense it into the amplification reaction container 30 provided by the second consumables supply device 600. The amplification device 300 is used to amplify the liquid in the amplification reaction container 30, which contains at least the nucleic acid extract, to obtain a test liquid; the detection device 400 is used to detect the test liquid.

[0292] As an embodiment, the first scheduling device 900 includes a first consumable material transport component 910 and a second consumable material transport component 920. The first consumable material transport component 910 is at least used to carry the nucleic acid extraction container 20 for linear motion along the first horizontal direction X, and the second consumable material transport component 920 is at least used to carry the amplification reaction container 30 for linear motion along the first horizontal direction X. The first consumable material transport component 910 and the second consumable material transport component 920 are spaced apart along the second horizontal direction Y. The first horizontal direction X is substantially perpendicular to the second horizontal direction Y. The first consumable material transport component 910 has a linear motion along the second horizontal direction Y. The first side and the second side are arranged in opposite directions along the second horizontal direction Y. The second consumable transport assembly 920 has a first side and a second side arranged in opposite directions along the second horizontal direction Y. The second side of the first consumable transport assembly 910 is arranged opposite the first side of the second consumable transport assembly 920. The sample storage device 800, the nucleic acid extraction device 200, and the amplification device 300 are at least partially distributed between the second side of the first consumable transport assembly 910 and the first side of the second consumable transport assembly 920, and two of the sample storage device 800, the nucleic acid extraction device 200, and the amplification device 300 are arranged side by side along the first horizontal direction X. In this embodiment, each functional module is located between the two consumable transport lines, and at least two functional modules are arranged side by side in either of the two approximately perpendicular horizontal directions. Using this arrangement, the purpose of reducing the single horizontal dimension of the sample analyzer 10 can also be achieved.

[0293] As an embodiment, the second consumables supply device 600 and the sample storage device 800 are distributed side by side along the first horizontal direction X, the nucleic acid extraction device 200 and the amplification device 300 are distributed side by side along the first horizontal direction X, and the sample storage device 800 and the nucleic acid extraction device 200 are distributed along the second horizontal direction Y.

[0294] As an embodiment, the nucleic acid extraction device 200 and the amplification device 300 are at least partially located on the first side of the second consumable material transport component 920.

[0295] As an embodiment, the second consumable material supply device 600 and the sample storage device 800 are at least partially located on the second side of the first consumable material conveying assembly 910 .

[0296] As an embodiment, the sample analyzer 10 also includes a reagent storage device 101 and a reagent dispensing device 102. The reagent storage device 101 is used to store reagents, and the reagent dispensing device 102 is used to draw reagents from the reagent storage device 101 and inject them into the nucleic acid extraction container 20 and / or the amplification reaction container 30; at least part of the second consumable supply device 600, the reagent storage device 101 and the sample storage device 800 are distributed side by side along the first horizontal direction X on the second side of the first consumable conveying component 910.

[0297] In addition to the above, other parts of the sample analyzer 10 provided in this embodiment can refer to the first to fifth embodiments and will not be described in detail here.

[0298] Embodiment seven:

[0299] The difference between the sample analyzer 10 provided in this embodiment and the first embodiment lies in the different protection focuses, which are specifically reflected in the following: in the first embodiment, the focus is on protecting the two consumables conveying lines of the nucleic acid extraction container 20 and the amplification reaction container 30, which are distributed side by side in the scheduling area in the middle of the sample analyzer 10, and at least part of the sample storage device 800, the nucleic acid extraction device 200, and the amplification device 300 are distributed on the opposite side of the scheduling area; while in this embodiment, the focus is on protecting the working positions of the nucleic acid extraction container 20, such as the sample loading position 9102 and the first transfer position 9103, formed in the middle scheduling area, and at least part of at least two of the sample storage device 800, the extraction device, and the amplification device 300 are distributed on the opposite side of the middle scheduling area, without limiting whether the middle scheduling area forms two consumables conveying lines.

[0300] Specifically, the sample analyzer 10 provided in this embodiment includes a first consumables supply device 500, a second consumables supply device 600, a sample storage device 800, a sample dispensing device 100, a nucleic acid extraction device 200, an amplification device 300, a detection device 400, a first dispatching device 900, a pipetting device 700, and a third dispatching device 104. The first consumables supply device 500 is used to provide at least a nucleic acid extraction container 20. The second consumables supply device 600 is used to provide at least an amplification reaction container 30. The first dispatching device 900 is used to carry at least a nucleic acid extraction container 20 for movement. The sample storage device 800 is used to store at least a sample container loaded with a sample. The sample dispensing device 100 is used to aspirate at least a portion of the sample from the sample container provided by the sample storage device 800 and dispense it into the nucleic acid extraction container 20 provided by the first consumables supply device 500 and located at the sample loading position 9102. The third dispatching device 104 is used to dispatch the nucleic acid extraction container 20, which is located at the first transfer position 9103 and loaded with at least a sample, to the nucleic acid extraction device 200. The nucleic acid extraction device 200 is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container 20 to obtain a nucleic acid extract solution. The pipetting device 700 is used to aspirate at least a portion of the nucleic acid extract solution from the nucleic acid extraction container 20 and dispense it into the amplification reaction container 30 provided by the second consumables supply device 600. The amplification device 300 is used to amplify the liquid containing at least the nucleic acid extract solution in the amplification reaction container 30 to obtain a test solution. The detection device 400 is used to detect the test solution.

[0301] In one embodiment, the first scheduling device 900 has a sample loading station 9102 and a first transfer station 9103 distributed along a first horizontal direction X. The first scheduling device 900 is used to carry at least the nucleic acid extraction container 20 for linear motion, so that the nucleic acid extraction container 20 is sequentially moved to the sample loading station 9102 and the first transfer station 9103. The first scheduling device 900 has a first side and a second side arranged on opposite sides along a second horizontal direction Y, which is substantially perpendicular to the first horizontal direction X. The sample storage device 800 is at least partially located on the first side of the first scheduling device 900, and at least partially located on the second side of at least one of the nucleic acid extraction device 200 and the amplification device 300. In this embodiment, a central scheduling area is formed with working stations for the nucleic acid extraction container 20, such as the sample loading station 9102 and the first transfer station 9103. The functional modules are distributed at least on opposite sides of the central scheduling area. The sample storage device 800 is located on one side of the central scheduling area, and at least partially located on the other side of at least one of the nucleic acid extraction device 200 and the amplification device 300. This configuration also helps reduce the single horizontal dimension of the sample analyzer 10 .

[0302] As an embodiment, both the nucleic acid extraction device 200 and the amplification device 300 are at least partially located on the second side of the first scheduling device 900, and the nucleic acid extraction device 200 and the amplification device 300 are distributed side by side along the first horizontal direction X.

[0303] As an embodiment, the first scheduling device 900 also has a first reagent dispensing position 9101, and the sample analyzer 10 also includes a reagent storage device 101 and a reagent dispensing device 102. The reagent storage device 101 is at least used to store the first type of reagent, and the reagent dispensing device 102 is at least used to absorb the first type of reagent from the reagent storage device 101 and dispense it into the nucleic acid extraction container 20; the first scheduling device 900 is used to carry the nucleic acid extraction container 20 to move to the first reagent dispensing position 9101, the sample loading position 9102, and the first transfer position 9103 in sequence; the reagent storage device 101 and the sample storage device 800 are distributed side by side along the first horizontal direction X and are at least partially located on the first side of the first scheduling device 900, and the nucleic acid extraction device 200 and the amplification device 300 are distributed side by side along the first horizontal direction X and are at least partially located on the second side of the first scheduling device 900.

[0304] As an embodiment, the first scheduling device 900 further includes a second reagent dispensing position 9201, a first liquid injection position 9202, a second transfer position 9203, a first liquid aspiration position 9205 and a third transfer position 9204; the third scheduling device 104 is further used to dispatch the nucleic acid extraction container 20 loaded with nucleic acid extract from the nucleic acid extraction device 200 to the third transfer position 9204; the first scheduling device 900 is further used to carry the amplification reaction container 30 from the second reagent dispensing position 9201 to the first liquid injection position 9202 and the second transfer position 9203 in sequence and to carry the nucleic acid extraction container 20 loaded with nucleic acid extract from the third transfer position 9204 to the first liquid aspiration position 9205; the reagent dispensing device 102 is used to aspirate nucleic acid from the reagent storage device 101 At least part of the second type of reagent is distributed in the amplification reaction container 30 located at the second reagent dispensing position 9201; the sample analyzer 10 also includes a fifth scheduling device 106 and a first magnetic attraction component 1001, the first magnetic attraction component 1001 is arranged next to the first liquid aspiration position 9205 for performing magnetic adsorption on the nucleic acid extract in the nucleic acid extraction container 20 located at the first liquid aspiration position 9205; the pipetting device 700 is used to draw at least part of the nucleic acid extract from the nucleic acid extraction container 20 located at the first liquid aspiration position 9205 and dispense it into the amplification reaction container 30 located at the first liquid injection position 9202; the fifth scheduling device 106 is used to schedule the amplification reaction container 30 located at the second transfer position 9203 and loaded with nucleic acid extract and second type of reagent to the amplification device 300.

[0305] In addition to the above, other parts of the sample analyzer 10 provided in this embodiment can refer to the first to sixth embodiments and will not be described in detail here.

[0306] Embodiment 8:

[0307] The difference between the sample analyzer 10 provided in this embodiment and the first embodiment lies in the different protection focuses, which are specifically reflected in the following: in the first embodiment, the focus is on protecting the two consumables conveying lines of the nucleic acid extraction container 20 and the amplification reaction container 30, which are distributed side by side in the scheduling area in the middle of the sample analyzer 10, and at least part of the sample storage device 800, the nucleic acid extraction device 200, and the amplification device 300 are distributed on the opposite side of the scheduling area; while in this embodiment, the focus is on protecting the working positions of the amplification reaction container 30, such as the second reagent dispensing position 9201, the first liquid filling position 9202, and the second transfer position 9203, formed in the middle scheduling area, and at least part of at least two of the sample storage device 800, the extraction device, and the amplification device 300 are distributed on the opposite side of the middle scheduling area, without limiting whether the middle scheduling area forms two consumables conveying lines.

[0308] Specifically, the sample analyzer 10 provided in this embodiment includes a first consumables supply device 500, a second consumables supply device 600, a sample storage device 800, a sample dispensing device 100, a reagent storage device 101, a reagent dispensing device 102, a nucleic acid extraction device 200, an amplification device 300, a detection device 400, a first scheduling device 900, a pipetting device 700, and a fifth scheduling device 106. The first consumables supply device 500 is used to provide at least a nucleic acid extraction container 20. The second consumables supply device 600 is used to provide at least an amplification reaction container 30. The first scheduling device 900 is used to carry at least the amplification reaction container 30 for movement. The sample storage device 800 is at least used to store a sample container loaded with a sample; the sample dispensing device 100 is used to draw at least part of the sample from the sample container provided by the sample storage device 800 and dispense it into the nucleic acid extraction container 20 provided by the first consumables supply device 500; the nucleic acid extraction device 200 is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container 20 to obtain a nucleic acid extract; the reagent dispensing device 102 is used to draw at least part of the second type of reagent from the reagent storage device 101 and dispense it into the amplification reaction container located at the second reagent dispensing position 9201. The device 30 is in the device; the pipetting device 700 is used to draw at least part of the nucleic acid extract from the nucleic acid extraction container 20 and inject it into the amplification reaction container 30 provided by the second consumables supply device 600 and located at the first injection position 9202; the fifth scheduling device 106 is used to schedule the amplification reaction container 30 located at the second transfer position 9203 and loaded with the nucleic acid extract and the second type of reagent to the amplification device 300; the amplification device 300 is used to amplify the liquid containing at least the nucleic acid extract in the amplification reaction container 30 to obtain the liquid to be tested; the detection device 400 is used to detect the liquid to be tested.

[0309] As an embodiment, the first scheduling device 900 has a second reagent dispensing position 9201, a first liquid injection position 9202 and a second transfer position 9203 distributed along the first horizontal direction X. The first scheduling device 900 is at least used to carry the amplification reaction container 30 for linear movement so that the amplification reaction container 30 moves from the second reagent dispensing position 9201 to the first liquid injection position 9202 and the second transfer position 9203 in sequence. The reagent storage device 101, the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 are distributed on at least two sides of the first scheduling device 900, and two of the reagent storage device 101, the sample storage device 800, the nucleic acid extraction device 200 and the amplification device 300 are distributed side by side along the first horizontal direction X and both are at least partially located on the same side of the first scheduling device 900. In this embodiment, the central scheduling area is formed with working positions for amplification reaction vessels 30, such as a second reagent dispensing position 9201, a first liquid injection position 9202, and a second transfer position 9203. Each functional module is distributed on at least two sides of the central scheduling area. Two of the reagent storage device 101, sample storage device 800, nucleic acid extraction device 200, and amplification device 300 are arranged side by side along the first horizontal direction X, and are at least partially located on the same side of the central scheduling area. This arrangement also helps reduce the single horizontal dimension of the sample analyzer 10.

[0310] As an embodiment, the first scheduling device 900 has a first side and a second side arranged on opposite sides along the second horizontal direction Y, the reagent storage device 101 and the sample storage device 800 are distributed side by side along the first horizontal direction X and are at least partially located on the first side of the first scheduling device 900, the nucleic acid extraction device 200 and the amplification device 300 are distributed side by side along the first horizontal direction X and are at least partially located on the second side of the first scheduling device 900, and the second horizontal direction Y is approximately perpendicular to the first horizontal direction X.

[0311] As an embodiment, the first scheduling device 900 also has a third transfer position 9204 and a first liquid aspiration position 9205; the first scheduling device 900 is also used to carry the nucleic acid extraction container 20 to move linearly from the third transfer position 9204 to the first liquid aspiration position 9205; the sample analyzer 10 also includes a third scheduling device 104 and a first magnetic attraction component 1001, the third scheduling device 104 is used to schedule the nucleic acid extraction container 20 loaded with nucleic acid extract from the nucleic acid extraction device 200 to the third transfer position 9204; the first magnetic attraction component 1001 is arranged next to the first liquid aspiration position 9205 for performing magnetic adsorption on the nucleic acid extract in the nucleic acid extraction container 20 located at the first liquid aspiration position 9205; the pipetting device 700 is used to absorb at least part of the nucleic acid extract from the nucleic acid extraction container 20 located at the first liquid aspiration position 9205 and inject it into the amplification reaction container 30 located at the first liquid injection position 9202.

[0312] In addition to the above, other parts of the sample analyzer 10 provided in this embodiment can refer to the first to seventh embodiments and will not be described in detail here.

[0313] The above description is only a preferred embodiment of the present invention and does not limit the patent scope of the present invention. All equivalent structural transformations made by using the contents of the present invention description and drawings under the inventive concept of the present invention, or direct / indirect application in other related technical fields are included in the patent protection scope of the present invention.

Claims

1. A sample analyzer comprising a first consumables supply device, a second consumables supply device, a sample storage device, a sample distribution device, a nucleic acid extraction device, an amplification device, a detection device, a first scheduling device, and a pipetting device; wherein: The first consumables supply device is at least used to provide a nucleic acid extraction container; The second consumables supply device is at least used to provide an amplification reaction container; The first scheduling device includes a first consumable conveying assembly and a second consumable conveying assembly, the first consumable conveying assembly is at least used to carry the nucleic acid extraction container for linear movement along a first horizontal direction, the second consumable conveying assembly is at least used to carry the amplification reaction container for linear movement along the first horizontal direction, the first consumable conveying assembly and the second consumable conveying assembly are arranged side by side along a second horizontal direction, the second horizontal direction is approximately perpendicular to the first horizontal direction, the first consumable conveying assembly has a first side and a second side arranged on opposite sides along the second horizontal direction, the second consumable conveying assembly has a first side and a second side arranged on opposite sides along the second horizontal direction, the second side of the first consumable conveying assembly is adjacent to the first side of the second consumable conveying assembly, at least a portion of at least one of the sample storage device, the nucleic acid extraction device and the amplification device is located on the first side of the first consumable conveying assembly, and at least a portion of at least the other of the sample storage device, the nucleic acid extraction device and the amplification device is located on the second side of the second consumable conveying assembly; The sample storage device is at least used to store a sample container loaded with a sample; The sample distributing device is used to draw at least part of the sample from the sample container provided by the sample storage device and dispense it into the nucleic acid extraction container provided by the first consumables supply device; The nucleic acid extraction device is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container to obtain a nucleic acid extraction solution; The pipetting device is used to draw at least part of the nucleic acid extraction solution from the nucleic acid extraction container and dispense it into the amplification reaction container provided by the second consumables supply device; The amplification device is used to amplify the liquid in the amplification reaction container containing at least the nucleic acid extract to obtain a liquid to be tested; The detection device is used to detect the liquid to be tested.

2. The sample analyzer according to claim 1, wherein the first consumable transport assembly comprises a first guide rail, a first movable seat, and a first driving mechanism, wherein the first guide rail extends along the first horizontal direction, the first movable seat is movably connected to the first guide rail for carrying the nucleic acid extraction container for linear motion along the first guide rail, and the first driving mechanism is used to drive the first movable seat for linear motion along the first guide rail; The second consumable material transport assembly includes a second guide rail, a second movable seat, and a second driving mechanism, wherein the second guide rail extends along the first horizontal direction, the second movable seat is at least used to carry the amplification reaction container to perform linear motion along the second guide rail, and the second driving mechanism is used to drive the second movable seat to perform linear motion along the second guide rail; in, The first guide rail and the second guide rail are arranged side by side along the second horizontal direction.

3. The sample analyzer according to claim 2, wherein a first receiving groove for placing the nucleic acid extraction container is provided on the top of the first movable seat, and the sample analyzer further comprises a second scheduling device and a third scheduling device, the second scheduling device being used to place the nucleic acid extraction container provided by the first consumable supply device into the first receiving groove from above the first movable seat, and the third scheduling device being used to remove the nucleic acid extraction container loaded with at least a sample placed in the first receiving groove from above the first movable seat and scheduling it to the nucleic acid extraction device; and / or, A second receiving groove for placing the amplification reaction container is provided on the top of the second movable seat. The sample analyzer also includes a fourth scheduling device and a fifth scheduling device. The fourth scheduling device is used to place the amplification reaction container provided by the second consumable supply device from above the second movable seat into the second receiving groove. The fifth scheduling device is used to take out the amplification reaction container placed in the second receiving groove and loaded with at least the nucleic acid extract from above the second movable seat and schedule it to the amplification device.

4. The sample analyzer according to claim 2, wherein the second movable seat is further configured to carry the nucleic acid extraction container to perform linear motion along the second guide rail; and / or The top of the second movable seat is also provided with a third receiving groove for placing the nucleic acid extraction container. The sample analyzer also includes a third scheduling device. The third scheduling device is used to schedule the nucleic acid extraction container loaded with the nucleic acid extraction liquid from the nucleic acid extraction device to the top of the second movable seat and place the nucleic acid extraction container from the top of the second movable seat into the third receiving groove, and to take out the nucleic acid extraction container placed in the third receiving groove from the top of the second movable seat and schedule it to the recovery position for recovery.

5. The sample analyzer according to any one of claims 1 to 4, wherein the first consumable material transport assembly comprises a first guide rail extending along the first horizontal direction, the sample analyzer further comprising a reagent storage device and a reagent dispensing device, the reagent storage device being used to store reagents, and the reagent dispensing device being used to dispense reagents provided by the reagent storage device into the nucleic acid extraction container and / or the amplification reaction container, and an orthographic projection of any one of the reagent storage device, the sample storage device, the nucleic acid extraction device, and the amplification device on any vertical plane parallel to the first horizontal direction at least partially overlaps with an orthographic projection of the first guide rail on the vertical plane; and / or, The second consumable material transport assembly includes a second guide rail, which extends along the first horizontal direction. The sample analyzer also includes a reagent storage device and a reagent dispensing device. The reagent storage device is used to store reagents, and the reagent dispensing device is used to dispense the reagents provided by the reagent storage device into the nucleic acid extraction container and / or the amplification reaction container. The orthographic projection of any one of the reagent storage device, the sample storage device, the nucleic acid extraction device and the amplification device on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the second guide rail on the vertical plane.

6. The sample analyzer according to any one of claims 1 to 4, wherein the sample storage device is located on a first side of the first consumable material transport assembly, and at least a portion of at least one of the nucleic acid extraction device and the amplification device is located on a second side of the second consumable material transport assembly; or The sample storage device is located on the second side of the second consumable material transport assembly, and at least a portion of at least one of the nucleic acid extraction device and the amplification device is located on the first side of the first consumable material transport assembly.

7. The sample analyzer as described in claim 6, wherein the sample storage device is located on the first side of the first consumable material transport assembly, the nucleic acid extraction device and the amplification device are at least partially located on the second side of the second consumable material transport assembly, and the nucleic acid extraction device and the amplification device are arranged side by side along the first horizontal direction.

8. The sample analyzer according to claim 7, further comprising a reagent storage device and a reagent dispensing device, wherein the reagent storage device is used to store reagents, and the reagent dispensing device is used to dispense the reagents provided by the reagent storage device into the nucleic acid extraction container and / or the amplification reaction container; The reagent storage device and the sample storage device are distributed side by side along the first horizontal direction on a first side of the first consumable material conveying assembly.

9. The sample analyzer according to claim 8, wherein the reagent storage device comprises a first reagent storage assembly and a second reagent storage assembly, and the reagent dispensing device comprises a first reagent dispensing assembly and a second reagent dispensing assembly; in, The first reagent storage assembly is used to store a first type of reagent, the first reagent dispensing assembly is used to draw the first type of reagent from the first reagent storage assembly and dispense it into the nucleic acid extraction container, and the nucleic acid extraction device is used to extract nucleic acid from the liquid in the nucleic acid extraction container containing at least a sample and the first type of reagent to obtain the nucleic acid extraction solution; The second reagent storage assembly is used to store a second type of reagent, the second reagent dispensing assembly is used to draw the second type of reagent from the second reagent storage assembly and dispense it into the amplification reaction container, and the amplification device is used to amplify the liquid in the amplification reaction container containing at least the nucleic acid extract and the second type of reagent to obtain the test liquid; At least part of the second consumable material supply device, the first reagent storage assembly, the second reagent storage assembly, and the sample storage device are distributed side by side in the first consumable material conveying assembly along the first horizontal direction. 10 . The sample analyzer according to claim 9 , wherein the distance between the sample storage device and the nucleic acid extraction device is shorter than the distance between the sample storage device and the amplification device.

11. The sample analyzer according to claim 9, wherein the first reagent dispensing assembly and the second reagent dispensing assembly are the same reagent dispensing assembly, and the same reagent dispensing assembly comprises a reagent needle, a first lifting mechanism, and a first horizontal movement mechanism; The reagent needle is used to draw the first type of reagent from the first reagent storage component and inject it into the nucleic acid extraction container, and is used to draw the second type of reagent from the second reagent storage component and inject it into the amplification reaction container; The output end of the first lifting mechanism is connected to the reagent needle to drive the reagent needle to move up and down; The output end of the first horizontal moving mechanism is connected to the first lifting mechanism to drive the first lifting mechanism to drive the reagent needle to move horizontally; The sample analyzer also includes a fourth scheduling device, which is used to transfer the amplification reaction container from the second consumable supply device to the second consumable conveying assembly. The fourth scheduling device includes a first clamping device and a second lifting mechanism. The first clamping device is used to clamp and release the amplification reaction container. The output end of the second lifting mechanism is connected to the first clamping device to at least drive the first clamping device to move up and down. The output end of the first horizontal moving mechanism is also connected to the second lifting mechanism to drive the second lifting mechanism to drive the first clamping device to move horizontally.

12. The sample analyzer according to claim 9, wherein the first consumable transport assembly has a first reagent dispensing position, a sample loading position, and a first transfer position distributed along the first horizontal direction, and the first consumable transport assembly is at least used to carry the nucleic acid extraction container and move it to the first reagent dispensing position, the sample loading position, and the first transfer position in sequence; The first reagent dispensing component is used to draw at least part of the first type of reagent from the first reagent storage component and inject it into the nucleic acid extraction container located at the first reagent injection position; The sample distributing device is used to draw at least part of the sample from the sample container and dispense it into the nucleic acid extraction container located at the sample loading position; The sample analyzer further includes a third scheduling device, which is used to schedule the nucleic acid extraction container located at the first transfer position and loaded with the sample and the first type of reagent to the nucleic acid extraction device.

13. The sample analyzer according to claim 12, wherein the first type of reagents comprises magnetic bead reagents, lysis reagents and elution reagents; The nucleic acid extraction container is formed with a reaction hole and a first liquid storage hole, the reaction hole is used to carry a liquid obtained by mixing at least a sample with a magnetic bead reagent, a lysis reagent and an elution reagent for nucleic acid extraction, and the first liquid storage hole is used to store the elution reagent; When the nucleic acid extraction container is located at the first reagent dispensing position, the first reagent dispensing component draws at least part of the magnetic bead reagent and the lysis reagent from the first reagent storage component and dispenses them into the reaction well, and draws at least part of the elution reagent from the first reagent storage component and dispenses it into the first liquid storage well; The first consumable material transport assembly is used to carry the nucleic acid extraction container loaded with at least a magnetic bead reagent, a lysis reagent, and an elution reagent from the first reagent dispensing position to the sample adding position; The third dispatching device is used to dispatch the nucleic acid extraction container located at the first transfer position and loaded with at least a sample and a magnetic bead reagent, a lysis reagent, and an elution reagent to the nucleic acid extraction device; The nucleic acid extraction device is further used to draw at least part of the elution reagent from the first liquid storage hole and inject it into the reaction hole during the nucleic acid extraction process.

14. The sample analyzer according to claim 13, wherein the first reagent storage component is further used to store silicone oil; The nucleic acid extraction container is further formed with a second liquid storage hole, and the second liquid storage hole is used to store silicone oil; When the nucleic acid extraction container is located at the first reagent dispensing position, the first reagent dispensing assembly is further used to draw at least part of the silicone oil from the first reagent storage assembly and dispense it into the second liquid storage hole; the first consumables conveying assembly is used to carry the nucleic acid extraction container loaded with at least magnetic bead reagent, lysis reagent, elution reagent, and silicone oil from the first reagent dispensing position to the sample loading position; The third dispatching device is used to dispatch the nucleic acid extraction container located at the first transfer position and loaded with at least a sample and a magnetic bead reagent, a lysis reagent, an elution reagent, and silicone oil to the nucleic acid extraction device; The pipetting device is further used to draw at least a portion of the silicone oil from the second liquid storage hole and inject it into the amplification reaction container loaded with the nucleic acid extract.

15. The sample analyzer according to claim 9, wherein the second consumable transport assembly has a second reagent dispensing position, a first liquid injection position, and a second transfer position distributed along the first horizontal direction, and the second consumable transport assembly is at least used to carry the amplification reaction container from the second reagent dispensing position to the first liquid injection position and the second transfer position in sequence; The second reagent dispensing assembly is used to draw at least part of the second type of reagent from the second reagent storage assembly and dispense it into the amplification reaction container located at the second reagent dispensing position; The liquid transfer device is used to draw at least a portion of the nucleic acid extraction solution from the nucleic acid extraction container and inject it into the amplification reaction container located at the first injection position; The sample analyzer further includes a fifth scheduling device, which is used to schedule the amplification reaction container located at the second transfer position and loaded with the nucleic acid extract and the second type of reagent to the amplification device.

16. The sample analyzer according to claim 15, wherein the second consumable material transport assembly further comprises a third transfer position and a first liquid aspiration position distributed along the first horizontal direction; The sample analyzer further includes a third dispatching device and a first magnetic attraction component, wherein the third dispatching device is used to dispatch the nucleic acid extraction container loaded with the nucleic acid extraction solution from the nucleic acid extraction device to the third transfer position; The second consumable material transport assembly is further used to carry the nucleic acid extraction container loaded with the nucleic acid extraction solution and move it from the third transfer position to the first liquid aspiration position; The first magnetic attraction component is disposed beside the first liquid aspiration position, and is used to magnetically attract the nucleic acid extraction liquid in the nucleic acid extraction container located at the first liquid aspiration position; The pipetting device is used to draw at least a portion of the nucleic acid extraction solution from the nucleic acid extraction container located at the first liquid aspiration position and inject it into the amplification reaction container located at the first liquid injection position.

17. The sample analyzer according to claim 16, wherein the second consumable material transport assembly comprises a second guide rail, a second movable seat, and a second drive mechanism, the second guide rail extending along the first horizontal direction, the second movable seat having a second receiving groove for accommodating the amplification reaction container and a third receiving groove for accommodating the nucleic acid extraction container on a top thereof, and the second drive mechanism being configured to drive the second movable seat to perform linear motion along the second guide rail; The sample analyzer further includes a controller and a sixth scheduling device, wherein the controller is configured to perform the following control actions: Controlling the sixth scheduling device to schedule the amplification reaction container provided by the second consumables supply device to the second reagent dispensing position and placing the amplification reaction container in the second containing slot of the second movable seat; Controlling the second reagent dispensing assembly to draw at least a portion of the second type of reagent from the second reagent storage assembly and inject it into the amplification reaction container placed on the second movable seat and located at the second reagent injection position; controlling the second driving mechanism to drive the second movable seat to perform linear motion along the second guide rail so that the second movable seat drives the amplification reaction container loaded with the second type of reagent to move, and moves the third receiving groove of the second movable seat to the third transfer position; Controlling the third dispatching device to dispatch the nucleic acid extraction container loaded with the nucleic acid extraction solution from the nucleic acid extraction device to the third transfer position and place it in the third containing groove of the second movable seat; controlling the second driving mechanism to drive the second movable seat to move the amplification reaction container loaded with the second type of reagent and the nucleic acid extraction container loaded with the nucleic acid extracting solution, so that the nucleic acid extraction container loaded with the nucleic acid extracting solution moves to the first liquid aspiration position, and the amplification reaction container loaded with the second type of reagent moves to the first liquid filling position; Controlling the pipetting device to draw at least a portion of the nucleic acid extraction solution from the nucleic acid extraction container located at the first liquid aspiration position and dispensing the solution into the amplification reaction container located at the first liquid injection position; Controlling the third dispatching device to remove the nucleic acid extraction container placed in the third containing tank and located at the first liquid aspiration position from above the second movable seat and dispatching it to a recovery position for discarding and recycling; Controlling the second driving mechanism to drive the second movable seat to move so as to move the amplification reaction container loaded with the nucleic acid extract and the second type of reagent from the first liquid filling position to the second transfer position; The fifth scheduling device is controlled to transfer the amplification reaction container located at the second transfer position and loaded with the nucleic acid extract and the second type of reagent to the amplification device.

18. The sample analyzer according to claim 8, wherein the first consumables supply device is disposed below the second consumables supply device, and the first consumables supply device extends from below the second consumables supply device to below the reagent storage device; and / or, The sample analyzer also includes a housing assembly, which is divided into a first chamber and a second chamber along the first horizontal direction. The second consumable supply device and the reagent storage device are distributed in the first chamber along the first horizontal direction, and the sample storage device is arranged in the second chamber; the reagent dispensing device includes a reagent needle, and the first chamber is provided with a first opening for the reagent needle to enter and exit; the sample dispensing device includes a sample needle, and the second chamber is provided with a second opening for the sample needle to enter and exit.

19. The sample analyzer according to any one of claims 1 to 4, wherein the first consumable transport assembly is used to carry the nucleic acid extraction container for movement but is not used to carry the amplification reaction container for movement, and the second consumable transport assembly is used to carry the amplification reaction container for movement and can be used to carry the nucleic acid extraction container for movement; and / or The first consumables supply device is also used to store pipette tips; the nucleic acid extraction container is formed with a reaction well and at least one pipette tip hole, the reaction well is used to carry a liquid obtained by mixing at least the sample and the first type of reagent for nucleic acid extraction, and the pipette tip hole is used to accommodate the pipette tip; the pipetting device is used to draw at least part of the nucleic acid extraction liquid from the nucleic acid extraction container through the pipette tip and inject it into the amplification reaction container.

20. The sample analyzer according to any one of claims 1 to 4, wherein the nucleic acid extraction device comprises a first functional component, a second functional component, and a scheduling component, the second functional component being arranged below or above the first functional component, the scheduling component being used to schedule the nucleic acid extraction container between the second functional component and the first functional component, the first functional component being used to at least carry the nucleic acid extraction container to perform a first functional action, the second functional component being used to at least carry the nucleic acid extraction container to perform a second functional action, the second functional action at least including an incubation action, the first functional action at least including a magnetic adsorption action and a liquid aspiration action; and / or, The nucleic acid extraction device has at least two workstations, each of which is used to carry the nucleic acid extraction container to perform a processing action. At least two of the workstations are distributed up and down in the vertical direction. The processing action includes at least one of incubation action, magnetic adsorption action, and liquid aspiration action.

21. A sample analyzer comprising a first consumables supply device, a second consumables supply device, a sample storage device, a sample distribution device, a nucleic acid extraction device, an amplification device, a detection device, a first scheduling device, and a pipetting device; wherein: The first consumables supply device is at least used to provide a nucleic acid extraction container; The second consumables supply device is at least used to provide an amplification reaction container; The first scheduling device includes at least one consumable material transport assembly, which is used to carry the nucleic acid extraction container and / or the amplification reaction container to move along a trajectory at least partially parallel to the first horizontal direction, wherein one of the consumable material transport assemblies has a first side and a second side arranged on opposite sides along the second horizontal direction, the second consumable material supply device and the sample storage device are distributed side by side along the first horizontal direction, and at least one of the two is at least partially located on the first side of the consumable material transport assembly, at least part of the nucleic acid extraction device and at least part of the amplification device are distributed side by side along the first horizontal direction, and both are at least partially located on the second side of the consumable material transport assembly, and the second horizontal direction is approximately perpendicular to the first horizontal direction; the orthographic projection of the consumable material transport assembly on any vertical plane parallel to the first horizontal direction and the orthographic projection of the nucleic acid extraction device on the vertical plane at least partially overlap, and the orthographic projection of the consumable material transport assembly on any vertical plane parallel to the first horizontal direction and the orthographic projection of the sample storage device on the vertical plane at least partially overlap; The sample storage device is at least used to store a sample container loaded with a sample; The sample distributing device is used to draw at least part of the sample from the sample container provided by the sample storage device and dispense it into the nucleic acid extraction container provided by the first consumables supply device; The nucleic acid extraction device is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container to obtain a nucleic acid extraction solution; The pipetting device is used to draw at least part of the nucleic acid extraction solution from the nucleic acid extraction container and dispense it into the amplification reaction container provided by the second consumables supply device; The amplification device is used to amplify the liquid in the amplification reaction container containing at least the nucleic acid extract to obtain a liquid to be tested; The detection device is used to detect the liquid to be tested.

22. The sample analyzer according to claim 21, wherein the at least one consumable transport assembly includes a first consumable transport assembly and a second consumable transport assembly, the first consumable transport assembly having a first side and a second side arranged on opposite sides along a second horizontal direction, the second consumable supply device and the sample storage device are distributed side by side along the first horizontal direction and the sample storage device is located on the first side of the first consumable transport assembly, at least part of the nucleic acid extraction device and at least part of the amplification device are distributed side by side along the first horizontal direction on the second side of the first consumable transport assembly, and the second consumable transport assembly is arranged along the second horizontal direction at a position where the nucleic acid extraction device and the amplification device are away from the first consumable transport assembly. On one side, the first consumable transport assembly is at least used to carry the nucleic acid extraction container for linear motion along the first horizontal direction, and the second consumable transport assembly is at least used to carry the amplification reaction container for linear motion along the first horizontal direction, the orthographic projection of at least one of the first consumable transport assembly and the second consumable transport assembly on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the nucleic acid extraction device on the vertical plane, and the orthographic projection of at least one of the first consumable transport assembly and the second consumable transport assembly on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the sample storage device in the vertical plane; or, The at least one consumable transport assembly includes a first consumable transport assembly and a second consumable transport assembly, the second consumable transport assembly has a first side and a second side arranged on opposite sides along a second horizontal direction, the second consumable supply device and the sample storage device are distributed side by side along the first horizontal direction and the sample storage device is located on the first side of the second consumable transport assembly, at least part of the nucleic acid extraction device and at least part of the amplification device are distributed side by side along the first horizontal direction on the second side of the second consumable transport assembly, the first consumable transport assembly is arranged on a side of the second consumable supply device and the sample storage device away from the second consumable transport assembly, and the first consumable transport assembly is provided. The component is at least used to carry the nucleic acid extraction container for linear motion along the first horizontal direction, and the second consumable material transport component is at least used to carry the amplification reaction container for linear motion along the first horizontal direction. The orthographic projection of at least one of the first consumable material transport component and the second consumable material transport component on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the nucleic acid extraction device on the vertical plane, and the orthographic projection of at least one of the first consumable material transport component and the second consumable material transport component on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the sample storage device on the vertical plane; or, The at least one consumable transport assembly includes a third consumable transport assembly, which has a first side and a second side arranged on opposite sides along the second horizontal direction, the second consumable supply device and the sample storage device are distributed side by side along the first horizontal direction, and the sample storage device is located on the first side of the third consumable transport assembly, at least part of the nucleic acid extraction device and at least part of the amplification device are distributed side by side along the first horizontal direction on the second side of the third consumable transport assembly, and the third consumable transport assembly is used to carry the nucleic acid extraction container and the amplification reaction container to move linearly along a straight track parallel to the first horizontal direction or along a U-shaped track partially parallel to the first horizontal direction. The orthographic projection of the third consumable transport assembly on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the nucleic acid extraction device on the vertical plane, and the orthographic projection of the third consumable transport assembly on any vertical plane parallel to the first horizontal direction at least partially overlaps with the orthographic projection of the sample storage device on the vertical plane.

23. The sample analyzer according to claim 21 or 22, further comprising a reagent storage device and a reagent dispensing device, wherein the reagent storage device is used to store reagents, and the reagent dispensing device is used to draw reagents from the reagent storage device and dispense them into the nucleic acid extraction container and / or the amplification reaction container; The second consumable supply device, the reagent storage device and the sample storage device are distributed side by side along the first horizontal direction, and at least part of at least two of the second consumable supply device, the reagent storage device and the sample storage device is located on the first side of one of the consumable transport components away from the nucleic acid extraction device and the amplification device.

24. A sample analyzer comprising a first consumables supply device, a second consumables supply device, a sample storage device, a sample distribution device, a nucleic acid extraction device, an amplification device, a detection device, a first scheduling device, and a pipetting device; wherein: The first consumables supply device is at least used to provide the nucleic acid extraction container; The second consumables supply device is at least used to provide the amplification reaction container; The first scheduling device includes a first consumable conveying assembly and a second consumable conveying assembly, the first consumable conveying assembly is at least used to carry the nucleic acid extraction container for linear movement along a first horizontal direction, the second consumable conveying assembly is at least used to carry the amplification reaction container for linear movement along the first horizontal direction, the first consumable conveying assembly and the second consumable conveying assembly are spaced apart along the second horizontal direction, the first horizontal direction is substantially perpendicular to the second horizontal direction, the first consumable conveying assembly has a first side and a second side arranged on opposite sides along the second horizontal direction, the second consumable conveying assembly has a first side and a second side arranged on opposite sides along the second horizontal direction, the second side of the first consumable conveying assembly is arranged opposite to the first side of the second consumable conveying assembly, the sample storage device, the nucleic acid extraction device and the amplification device are at least partially distributed between the second side of the first consumable conveying assembly and the first side of the second consumable conveying assembly, and the sample storage device, the nucleic acid extraction device and the amplification device are distributed side by side along the first horizontal direction; The sample storage device is at least used to store a sample container loaded with a sample; The sample distributing device is used to draw at least part of the sample from the sample container provided by the sample storage device and dispense it into the nucleic acid extraction container provided by the first consumables supply device; The nucleic acid extraction device is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container to obtain a nucleic acid extraction solution; The pipetting device is used to draw at least part of the nucleic acid extraction solution from the nucleic acid extraction container and dispense it into the amplification reaction container provided by the second consumables supply device; The amplification device is used to amplify the liquid in the amplification reaction container containing at least the nucleic acid extract to obtain a liquid to be tested; The detection device is used to detect the liquid to be tested.

25. The sample analyzer according to claim 24, wherein the second consumables supply device and the sample storage device are arranged side by side along the first horizontal direction, the nucleic acid extraction device and the amplification device are arranged side by side along the first horizontal direction, and the sample storage device and the nucleic acid extraction device are arranged along the second horizontal direction; and / or, The sample analyzer also includes a reagent storage device and a reagent dispensing device, the reagent storage device is used to store reagents, and the reagent dispensing device is used to draw reagents from the reagent storage device and inject them into the nucleic acid extraction container and / or the amplification reaction container; at least part of the second consumable supply device, the reagent storage device and the sample storage device are distributed side by side along the first horizontal direction on the second side of the first consumable conveying assembly.

26. A sample analyzer comprising a first consumables supply device, a second consumables supply device, a sample storage device, a sample distribution device, a nucleic acid extraction device, an amplification device, a detection device, a first scheduling device, a pipetting device, and a third scheduling device; wherein: The first consumables supply device is at least used to provide the nucleic acid extraction container; The second consumables supply device is at least used to provide the amplification reaction container; The first scheduling device has a sample loading position and a first transfer position distributed along a first horizontal direction, the first scheduling device is at least used to carry a nucleic acid extraction container for linear motion so that the nucleic acid extraction container is moved sequentially to the sample loading position and the first transfer position, the first scheduling device has a first side and a second side arranged on opposite sides along a second horizontal direction, the second horizontal direction is substantially perpendicular to the first horizontal direction, the sample storage device is at least partially located on the first side of the first scheduling device, and at least one of the nucleic acid extraction device and the amplification device is at least partially located on the second side of the first scheduling device; The sample storage device is at least used to store a sample container loaded with a sample; The sample distributing device is used to draw at least part of the sample from the sample container provided by the sample storage device and dispense it into the nucleic acid extraction container provided by the first consumable supply device and located at the sample loading position; The third dispatching device is used to dispatch the nucleic acid extraction container located at the first transfer position and loaded with at least a sample to the nucleic acid extraction device; The nucleic acid extraction device is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container to obtain a nucleic acid extraction solution; The pipetting device is used to draw at least part of the nucleic acid extraction solution from the nucleic acid extraction container and dispense it into the amplification reaction container provided by the second consumables supply device; The amplification device is used to amplify the liquid in the amplification reaction container containing at least the nucleic acid extract to obtain a liquid to be tested; The detection device is used to detect the liquid to be tested.

27. The sample analyzer according to claim 26, wherein the first scheduling device further has a first reagent dispensing position, and the sample analyzer further comprises a reagent storage device and a reagent dispensing device, wherein the reagent storage device is at least used to store a first type of reagent, and the reagent dispensing device is at least used to absorb the first type of reagent from the reagent storage device and dispense it into the nucleic acid extraction container; the first scheduling device is used to carry the nucleic acid extraction container to move to the first reagent dispensing position, the sample loading position, and the first transfer position in sequence; the reagent storage device and the sample storage device are distributed side by side along the first horizontal direction and are both at least partially located on the first side of the first scheduling device, and the nucleic acid extraction device and the amplification device are distributed side by side along the first horizontal direction and are both at least partially located on the second side of the first scheduling device; and / or, The first scheduling device also has a second reagent dispensing position, a first liquid injection position, a second transfer position, a first liquid aspiration position, and a third transfer position; the third scheduling device is also used to dispatch the nucleic acid extraction container loaded with the nucleic acid extract from the nucleic acid extraction device to the third transfer position; the first scheduling device is also used to carry the amplification reaction container from the second reagent dispensing position to the first liquid injection position and the second transfer position in sequence, and to carry the nucleic acid extraction container loaded with the nucleic acid extract from the third transfer position to the first liquid aspiration position; the reagent dispensing device is used to absorb at least part of the second type of reagent from the reagent storage device and distribute it to the reagent storage device located at the first liquid aspiration position. The sample analyzer further comprises a fifth scheduling device and a first magnetic attraction component, wherein the first magnetic attraction component is arranged beside the first liquid aspiration position to perform magnetic adsorption on the nucleic acid extract in the nucleic acid extraction container located at the first liquid aspiration position; the pipetting device is used to draw at least part of the nucleic acid extract from the nucleic acid extraction container located at the first liquid aspiration position and dispense it into the amplification reaction container located at the first liquid injection position; the fifth scheduling device is used to schedule the amplification reaction container located at the second transfer position and loaded with the nucleic acid extract and the second type of reagent to the amplification device.

28. A sample analyzer comprising a first consumables supply device, a second consumables supply device, a sample storage device, a sample dispensing device, a reagent storage device, a reagent dispensing device, a nucleic acid extraction device, an amplification device, a detection device, a first scheduling device, a pipetting device, and a fifth scheduling device; wherein: The first consumables supply device is at least used to provide the nucleic acid extraction container; The second consumables supply device is at least used to provide the amplification reaction container; The first scheduling device has a second reagent dispensing position, a first liquid injection position, and a second transfer position distributed along a first horizontal direction. The first scheduling device is at least used to carry the amplification reaction container for linear motion so that the amplification reaction container moves from the second reagent dispensing position to the first liquid injection position and the second transfer position in sequence. The reagent storage device, the sample storage device, the nucleic acid extraction device, and the amplification device are distributed on at least two sides of the first scheduling device, and two of the reagent storage device, the sample storage device, the nucleic acid extraction device, and the amplification device are distributed side by side along the first horizontal direction and are at least partially located on the same side of the first scheduling device. The sample storage device is at least used to store a sample container loaded with a sample; The sample distributing device is used to draw at least part of the sample from the sample container provided by the sample storage device and dispense it into the nucleic acid extraction container provided by the first consumables supply device; The nucleic acid extraction device is used to extract nucleic acid from the liquid containing at least the sample in the nucleic acid extraction container to obtain a nucleic acid extraction solution; The reagent dispensing device is used to draw at least part of the second type of reagent from the reagent storage device and inject it into the amplification reaction container located at the second reagent injection position; The pipetting device is used to draw at least part of the nucleic acid extraction solution from the nucleic acid extraction container and inject it into the amplification reaction container provided by the second consumables supply device and located at the first injection position; The fifth dispatching device is used to dispatch the amplification reaction container located at the second transfer position and loaded with the nucleic acid extract and the second type of reagent to the amplification device; The amplification device is used to amplify the liquid in the amplification reaction container containing at least the nucleic acid extract to obtain a liquid to be tested; The detection device is used to detect the liquid to be tested.

29. The sample analyzer of claim 28, wherein the first scheduling device has a first side and a second side arranged on opposite sides along a second horizontal direction, the reagent storage device and the sample storage device are arranged side by side along the first horizontal direction and are both at least partially located on the first side of the first scheduling device, the nucleic acid extraction device and the amplification device are arranged side by side along the first horizontal direction and are both at least partially located on the second side of the first scheduling device, and the second horizontal direction is substantially perpendicular to the first horizontal direction; and / or The first scheduling device also has a third transfer position and a first liquid aspiration position; the first scheduling device is also used to carry the nucleic acid extraction container to move linearly from the third transfer position to the first liquid aspiration position; the sample analyzer also includes a third scheduling device and a first magnetic attraction component, the third scheduling device is used to schedule the nucleic acid extraction container loaded with the nucleic acid extract from the nucleic acid extraction device to the third transfer position; the first magnetic attraction component is arranged next to the first liquid aspiration position to perform magnetic adsorption on the nucleic acid extract in the nucleic acid extraction container located at the first liquid aspiration position; the pipetting device is used to absorb at least part of the nucleic acid extract from the nucleic acid extraction container located at the first liquid aspiration position and inject it into the amplification reaction container located at the first injection position.

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