Anti-trop2 antibody and Anti-5t4 antibody-natural killer cell conjugate and use thereof

WO2025214486A1PCT designated stage Publication Date: 2025-10-16IMBIORAY (HANGZHOU) BIOMEDICINE CO LTD
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Patent Information

Application Number
PCT/CN2025/088571
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-04-12
Filing Date
2025-04-11
Publication Date
2025-10-16

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Abstract

Provided are an anti-Trop2 antibody and anti-5T4 antibody-natural killer cell conjugate, a pharmaceutical composition comprising the conjugate, and pharmaceutical use of the conjugate and a preparation method therefor.
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Citation Information

Patent Citations

  • Disease Therapy With Chimeric Antigen Receptor (Car) Constructs And T Cells (Car-T) Or Nk Cells (Car-Nk) Expressing Car Constructs

    CN107708741A

  • Methods of activation and expansion of natural killer cells and combinations with bispecific antibodies

    CN117295517A

  • Anti-5T4 antibody-natural killer cell conjugate and application thereof

    CN117482245A

  • Anti-Trop2 antibody and anti-5T4 antibody-natural killer cell conjugates and uses thereof

    CN119215188A