Radiation therapy device, and automatic search system and method for maximum beam intensity of accelerator

The accelerator's maximum current intensity automatic search system enables remote and automated adjustment of the ion source position, solving the problem of low ion source adjustment efficiency, improving the accuracy of beam intensity and adjustment efficiency, and ensuring the effectiveness of radiotherapy.

WO2025218766A1PCT designated stage Publication Date: 2025-10-23MEVION MEDICAL EQUIPMENT CO LTD
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Patent Information

Application Number
PCT/CN2025/089718
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-04-19
Filing Date
2025-04-18
Publication Date
2025-10-23

AI Technical Summary

Technical Problem

In existing technologies, the ion source position adjustment is inefficient, the adjustment process is discontinuous and inaccurate, which affects the beam intensity and radiotherapy effect, and the adjustment personnel are exposed to radiation.

Method used

An automatic maximum beam intensity search system for accelerators is adopted, which provides a symmetrical electric field through two ion sources. The position of the ion sources is remotely and automatically adjusted using a drive component and a recording module. Combined with a storage and search module, the system automatically finds the maximum beam intensity.

Benefits of technology

It improves the precision and efficiency of ion source position adjustment, ensures the accuracy of beam intensity, reduces radiation exposure for adjustment personnel, and enhances the effectiveness of radiotherapy.

✦ Generated by Eureka AI based on patent content.

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Abstract

Disclosed in the present invention are a radiation therapy device, and an automatic search system and method for the maximum beam intensity of an accelerator. The system comprises: a cyclotron; a first driving assembly that is separately connected to the cyclotron and a first ion source and used for driving, according to a preset step size, the first ion source to move away from a second ion source; a second driving assembly that is separately connected to the cyclotron and the second ion source and used for driving, according to the preset step size, the second ion source to move away from the first ion source; a recording module that is connected to the first driving assembly and the second driving assembly and used for recording all first positions and second positions of the movement of the first ion source and the second ion source and combining each first position and each second position to obtain all position combinations; a debugging module that is used for controlling the cyclotron to emit beams under each position combination and introducing, accelerating and extracting protons generated by the first ion source and the second ion source; a storage module that is used for acquiring and storing a beam intensity corresponding to each position combination to form a data set; and a search module that is used for searching the data set for the maximum beam intensity, ensuring a better radiation therapy effect.
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Description

Radiotherapy device, accelerator maximum flow strength automatic search system and method

[0001] This application claims priority to the Chinese patent application No. CN202410476214.X, filed on April 19, 2024, which is incorporated by reference in its entirety. TECHNICAL FIELD

[0002] The present application relates to the technical field of high-end medical equipment, for example to a radiotherapy device, an accelerator maximum flow strength automatic search system and method. BACKGROUND

[0003] The ion source is a subsystem of the accelerator, which generates protons in the center of the accelerator. The protons generated by the ion source need to be brought into the center of the accelerator at the correct time with precise position, so as to be successfully accelerated to high energy under the combined action of the radio frequency and magnet subsystems. The proton ion source uses gaseous hydrogen as the starting raw material, and generates protons by ionizing hydrogen through the application of certain electromagnetic energy (electric spark, high-voltage electric field, electron bombardment, plasma shaping, etc.).

[0004] The ion source is fixed in the center of the cyclotron, so that the deviation of the ion source from the designed vertical source position is within 0.1 mm; the ion source must be positioned within the ion source emission area with a deviation of about 10%. The ion source must be positioned at the horizontal design source position relative to the radio frequency extraction electrode, and a certain adjustment range is reserved to cope with the influence of changes in other parameters of the accelerator. The center electrode and the magnet are mutually referenced to generate a proton pulse at the correct position, i.e. collimated to within 0.5 mm, so as to be subsequently accelerated and extracted.

[0005] In order to meet the requirements of radiotherapy, the medical accelerator in the radiotherapy device needs to provide stable and sufficient particle beams within a certain time. In order to fully meet the needs of hospitals, higher beam intensity needs to be achieved in the factory. According to the theoretical design of the accelerator, the deviation of the ion source from the theoretical position will affect the beam intensity of the accelerator, resulting in low beam quality, so it needs to be adjusted multiple times in the iteration process. The current process flow is that the debugging personnel enter the accelerator room to manually adjust the ion source probe micrometer, and then output the beam for measurement to find the maximum flow strength reading and the micrometer position.

[0006] The above-mentioned debugging process has the following problems and shortcomings:

[0007] 1. Manual adjustment: after the beam output is completed at each micrometer position of the ion source adjustment, it needs to wait for ten minutes for the radiation level in the machine room to decrease to the level acceptable to the human body before entering the machine room again for ion source position adjustment, which seriously affects the beam debugging efficiency.

[0008] 2. The adjustment process is discontinuous: the current adjustment mode cannot realize continuous adjustment, and is easily affected by other variables during the adjustment process, resulting in more adjustments and reducing the adjustment efficiency.

[0009] 3. Non-automation: the current beam output and recorded current are manually performed, the current is recorded in an Excel table, and the maximum current and corresponding micrometer position are determined, which is low in efficiency.

[0010] 4. Low accuracy: manual adjustment of the ion source position has a large adjustment error, and the inaccuracy of the ion source position affects the accuracy of the beam intensity, that is, time is consumed and the accuracy of the beam intensity cannot be guaranteed, which affects the beam quality and even the radiation treatment effect on patients.

[0011] The present application solves one or more of the problems described in the background art. SUMMARY

[0012] The present application aims to provide an accelerator maximum current automatic search system and method, which realizes remote automatic adjustment of the ion source position, improves the accuracy of the ion source position adjustment, guarantees the accuracy of the beam intensity, improves the adjustment efficiency and accuracy, avoids radiation of the adjustment personnel, and meets the requirements of radiation treatment.

[0013] The object of the present application is achieved by the following technical solutions:

[0014] In a first aspect of the present application, an accelerator maximum current automatic search system is provided, comprising:

[0015] A cyclotron having a first outlet end and a second outlet end arranged opposite along a length direction, for accommodating a first ion source and a second ion source arranged opposite along the length direction;

[0016] A first driving assembly, a fixed end of the first driving assembly being connected with the first outlet end of the cyclotron, and a driving end of the first driving assembly being connected with the first ion source, for driving the first ion source to move in position along an axial direction away from the second ion source;

[0017] A second driving assembly, a fixed end of the second driving assembly being connected with the second outlet end of the cyclotron, and a driving end of the second driving assembly being connected with the second ion source, for driving the second ion source to move in position along an axial direction away from the first ion source;

[0018] A recording module connected with the first driving assembly and the second driving assembly respectively, for recording all first positions of the first ion source position movement and all second positions of the second ion source position movement respectively, combining each first position with each second position to obtain all position combinations;

[0019] a debugging module configured to set a preset step length, and control the first driving assembly to drive the first ion source to move in position according to the preset step length and control the second driving assembly to drive the second ion source to move in position according to the preset step length;

[0020] a control module configured to control the cyclotron to emit a beam at each position combination, so that the cyclotron simultaneously introduces, accelerates and emits protons generated by the first ion source and the second ion source;

[0021] a storage module configured to obtain a beam intensity corresponding to each position combination, and store each beam intensity to form a data set including all beam intensities;

[0022] a search module configured to search for a maximum beam intensity from the data set, the maximum beam intensity corresponding to an optimal position combination, the optimal position combination including an optimal first position of the first ion source and an optimal second position of the second ion source.

[0023] Compared with the prior art, the present application has the following advantages: by providing two ion sources, i.e., the first ion source and the second ion source, a symmetrical electric field is provided, and it is ensured that the electric field is large enough, so that the first ion source and the second ion source can simultaneously form sufficient plasma to generate sufficient protons, which facilitates searching for the maximum beam intensity; by controlling the first driving assembly to adjust the position of the first ion source and the second driving assembly to adjust the position of the second ion source according to the preset step length, remote adjustment of the positions of the ion sources is realized, so that the radiation safety problem and the waiting time caused by the adjustment of the positions of the ion sources by the debugging personnel each time entering the machine room and the cylinder are not considered, the debugging personnel are protected from radiation, and the beam debugging efficiency is improved; by automatic adjustment of the positions of the ion sources and automatic search for the maximum beam intensity, the beam debugging accuracy and the debugging efficiency are improved, a better radiotherapy effect is ensured, and proton therapy is more quickly popularized.

[0024] In some possible implementation manners, the first ion source and the second ion source are not in contact with each other, and a minimum installation gap is arranged between the first initial position of the first ion source and the second initial position of the second ion source, the minimum installation gap is 0.508 mm, and the position moving distance of the first ion source from the first initial position to the first maximum target position and the position moving distance of the second ion source from the second initial position to the second maximum target position are both not more than 1 mm.

[0025] In some possible implementation manners, the first driving assembly includes:

[0026] a first connecting frame having opposite first and second ends;

[0027] a first servo motor having a fixed end and a driving end, the fixed end of the first servo motor being connected to the first end of the first connecting frame;

[0028] a first transmission shaft having opposite first and second ends, the first end of the first transmission shaft being connected to the driving end of the first servo motor through a first coupling;

[0029] a first ball screw having opposite first and second ends, the first end of the first ball screw being connected to the second end of the first transmission shaft through a second coupling;

[0030] a first bearing seat disposed on the first connecting frame and away from the second end of the first connecting frame, the first bearing seat being sleeved on and connected to the first ball screw and located near the first end of the first ball screw;

[0031] a second bearing seat disposed on the first connecting frame and close to the second end of the first connecting frame, the second bearing seat being sleeved on and connected to the first ball screw and located near the second end of the first ball screw;

[0032] a first shaft sleeve assembly sleeved on and connected to the first ball screw and located between the first and second bearing seats, the first shaft sleeve assembly being connected to the first ion source.

[0033] In some possible implementations, the second driving assembly includes:

[0034] a second connecting frame having opposite first and second ends;

[0035] a second servo motor having a fixed end and a driving end, the fixed end of the second servo motor being connected to the first end of the second connecting frame;

[0036] a second transmission shaft having opposite first and second ends, the first end of the second transmission shaft being connected to the driving end of the second servo motor through a third coupling;

[0037] a second ball screw having opposite first and second ends, the first end of the second ball screw being connected to the second end of the second transmission shaft through a fourth coupling;

[0038] a third bearing seat disposed on the second connecting frame and away from the second end of the second connecting frame, the third bearing seat being sleeved on and connected to the second ball screw and located near the first end of the second ball screw;

[0039] a fourth bearing seat disposed on the second connecting frame and close to the second end of the second connecting frame, the fourth bearing seat being sleeved on and connected with the second ball screw and located close to the second end of the second ball screw;

[0040] a second shaft sleeve assembly sleeved on and connected with the second ball screw and located between the third bearing seat and the fourth bearing seat, the second shaft sleeve assembly being connected with the second ion source.

[0041] In some possible implementations, the first connecting frame is in an L shape and includes:

[0042] a first horizontal plate having a first surface and a second surface oppositely arranged along a thickness direction, one end of the first horizontal plate being connected with the fixed end of the first servo motor, and the first bearing seat and the second bearing seat being both disposed on the first surface of the first horizontal plate;

[0043] a first vertical plate having a first end and a second end, the first end of the first vertical plate being connected with the second surface of the first horizontal plate perpendicularly, and the second end of the first vertical plate being connected with the first outlet end of the cyclotron;

[0044] a first reinforcing plate having a first surface and a second surface perpendicularly arranged, the first surface of the first reinforcing plate being connected with the second surface of the first horizontal plate, and the second surface of the first reinforcing plate being connected with one surface of the first vertical plate.

[0045] In some possible implementations, the second connecting frame is in an L shape and includes:

[0046] a second horizontal plate having a first surface and a second surface oppositely arranged along a thickness direction, one end of the second horizontal plate being connected with the fixed end of the second servo motor, and the third bearing seat and the fourth bearing seat being both disposed on the first surface of the second horizontal plate;

[0047] a second vertical plate having a first end and a second end, the first end of the second vertical plate being connected with the second surface of the second horizontal plate perpendicularly, and the second end of the second vertical plate being connected with the second outlet end of the cyclotron;

[0048] a second reinforcing plate having a first surface and a second surface perpendicularly arranged, the first surface of the second reinforcing plate being connected with the second surface of the second horizontal plate, and the second surface of the second reinforcing plate being connected with one surface of the second vertical plate.

[0049] In some possible implementations, the first shaft sleeve assembly includes:

[0050] a first nut sleeve sleeved on and connected with the first ball screw;

[0051] A first fixed sleeve is sleeved on the first nut sleeve, and two ends of the first fixed sleeve are respectively connected with first side fixing members;

[0052] The first side fixing member has a first end and a second end along a length direction, the first end of the first side fixing member is connected with the first fixed sleeve, and the second end of the first side fixing member is connected with the first ion source.

[0053] In some possible implementations, the second shaft sleeve assembly comprises:

[0054] A second nut sleeve is sleeved on the second ball screw and connected with the second ball screw;

[0055] A second fixed sleeve is sleeved on the second nut sleeve, and two ends of the second fixed sleeve are respectively connected with second side fixing members;

[0056] The second side fixing member has a first end and a second end along a length direction, the first end of the second side fixing member is connected with the second fixed sleeve, and the second end of the second side fixing member is connected with the second ion source.

[0057] According to a second aspect of the present application, an accelerator maximum beam intensity automatic search method is provided, which is applied to the accelerator maximum beam intensity automatic search system, and the method comprises the following steps:

[0058] The preset step length is set;

[0059] The first driving assembly is controlled to drive the first ion source to move from a first initial position to a first maximum target position, and the second driving assembly is controlled to drive the second ion source to move from a second initial position to a second maximum target position according to the preset step length;

[0060] All first positions in the movement of the first ion source from the first initial position to the first maximum target position and all second positions in the movement of the second ion source from the second initial position to the second maximum target position are recorded, each first position is combined with each second position, and all position combinations are obtained;

[0061] The cyclotron is controlled to perform beam emission under each position combination, so that the cyclotron sequentially performs introduction, acceleration and emission on protons generated by the first ion source and the second ion source;

[0062] The beam intensity corresponding to each position combination is obtained, each beam intensity is stored, and a data set comprising all beam intensities is formed;

[0063] searching a maximum beam intensity from the data set, the maximum beam intensity corresponding to an optimal position combination, the optimal position combination including an optimal first position of the first ion source and an optimal second position of the second ion source.

[0064] In some possible implementation manners, the distance from the first initial position to the first maximum target position and the distance from the second initial position to the second maximum target position can be configured to be equal or unequal.

[0065] In some possible implementation manners, the preset step length includes a coarse adjustment step length and a fine adjustment step length, and when the coarse adjustment step length is greater than the fine adjustment step length, the method includes:

[0066] a coarse adjustment stage: respectively controlling the first driving assembly to drive the first ion source to move from the first initial position to a first preset position according to the coarse adjustment step length, and controlling the second driving assembly to drive the second ion source to move from the second initial position to a second preset position according to the coarse adjustment step length;

[0067] respectively recording all first positions in the process that the first ion source moves from the first initial position to the first preset position and all second positions in the process that the second ion source moves from the second initial position to the second preset position, combining each first position with each second position to obtain all first position combinations;

[0068] controlling the cyclotron to perform beam emission under each first position combination, so that the cyclotron simultaneously performs introduction, acceleration and introduction of protons generated by the first ion source and the second ion source in sequence;

[0069] obtaining a first beam intensity corresponding to each first position combination, and storing each first beam intensity to form a first data set including all first beam intensities;

[0070] searching a maximum first beam intensity from the first data set;

[0071] obtaining an optimal first position combination corresponding to the maximum first beam intensity, the optimal first position combination including an optimal first position of the first ion source and an optimal second position of the second ion source;

[0072] a fine adjustment stage: respectively controlling the first driving assembly to drive the first ion source to move from the optimal first position to a third preset position according to the fine adjustment step length, and controlling the second driving assembly to drive the second ion source to move from the optimal second position to a fourth preset position according to the fine adjustment step length;

[0073] record all third positions of the first ion source moving from the optimal first position to the third preset position and all fourth positions of the second ion source moving from the optimal second position to the fourth preset position, combine each third position with each fourth position to obtain all second position combinations;

[0074] control the cyclotron to perform beam emission under each second position combination, so that the cyclotron sequentially performs introduction, acceleration and emission on protons generated by the first ion source and the second ion source;

[0075] obtain a second beam intensity corresponding to each second position combination, and store each second beam intensity to form a second data set including all second beam intensities;

[0076] search for a maximum second beam intensity from the second data set;

[0077] obtain an optimal second position combination corresponding to the maximum second beam intensity, the optimal second position combination including an optimal third position of the first ion source and an optimal fourth position of the second ion source.

[0078] In some possible implementation manners, the third preset position includes a first initial position or a first maximum target position, and the fourth preset position includes a second initial position or a second maximum target position.

[0079] In some possible implementation manners, the preset step length includes a first step length, a second step length,..., and an Nth step length, and the first step length > the second step length >... > the Nth step length.

[0080] In a third aspect, the present application provides a radiotherapy device, which includes the accelerator maximum flow strength automatic search system and applies the accelerator maximum flow strength automatic search method. BRIEF DESCRIPTION OF DRAWINGS

[0081] FIG. 1 is a structural schematic diagram of an accelerator maximum flow strength automatic search system according to an embodiment of the present application;

[0082] FIG. 2 is a position structural schematic diagram of a cyclotron and a first driving assembly and a second driving assembly according to an embodiment of the present application;

[0083] FIG. 3 is a position structural schematic diagram of a cyclotron and a first driving assembly according to an embodiment of the present application;

[0084] FIG. 4A is a structural schematic diagram of a first driving assembly and a second driving assembly according to an embodiment of the present application;

[0085] Fig. 4B is an enlarged view of S1 in Fig. 4A;

[0086] Fig. 5A is a structural schematic diagram of the first driving assembly and the second driving assembly according to an embodiment of the present application;

[0087] Fig. 5B is an enlarged view of S2 in Fig. 5A;

[0088] Fig. 6 is a schematic diagram of the positions of the first ion source and the second ion source in the case of a preset step length according to an embodiment of the present application;

[0089] Fig. 7 is a schematic diagram of the positions of the first ion source and the second ion source in the case of a preset step length including a coarse adjustment step length and a fine adjustment step length according to an embodiment of the present application;

[0090] Fig. 8 is a flow chart of the steps of the accelerator maximum current automatic search method according to an embodiment of the present application.

[0091] In the drawings: 1, cyclotron; 2, first ion source; 3, second ion source; 4, first driving assembly; 5, second driving assembly; 6, recording module; 7, debugging module; 8, storage module; 9, search module; 40, first connecting frame; 41, first servo motor; 42, first transmission shaft; 43, first coupling; 44, first ball screw; 45, second coupling; 46, first bearing seat; 47, second bearing seat; 48, first shaft sleeve assembly; 50, second connecting frame; 51, second servo motor; 52, second transmission shaft; 53, third coupling; 54, second ball screw; 55, fourth coupling; 56, third bearing seat; 57, fourth bearing seat; 58, second shaft sleeve assembly; 400, first cross plate; 401, first vertical plate; 402, first reinforcing plate; 500, second cross plate; 501, second vertical plate; 502, second reinforcing plate; 480, first nut sleeve; 481, first fixed sleeve; 482, first side fixing member; 580, second nut sleeve; 581, second fixed sleeve; 582, second side fixing member. DETAILED DESCRIPTION

[0092] Example embodiments now will be described more fully hereinafter with reference to the accompanying drawings. Example embodiments, however, can be implemented in many different forms and should not be construed as limited to the implementations set forth herein; rather, these implementations are provided so that this disclosure will be thorough and complete, and will fully convey the scope of example embodiments to those skilled in the art. Like reference numerals refer to like elements throughout the figures, and descriptions of the same elements will not be repeated.

[0093] The words expressing position and direction described in the present application are explained by taking the drawings as an example, but changes can also be made according to needs, and the changes made are all included in the protection scope of the present application.

[0094] Example implementations will now be described with reference to the drawings. Example implementations can, however, be implemented in many different forms and should not be construed as limited to the implementations set forth herein; rather, these implementations are provided so that this disclosure will be thorough and complete, and will fully convey the inventive aspects of the example implementations to those skilled in the art.

[0095] Referring to FIGS. 1-3, the present embodiment provides an accelerator maximum flow strength automatic search system, which includes a cyclotron 1, a first driving assembly 4, a second driving assembly 5, a first ion source 2, a second ion source 3, a recording module 6, a debugging module 7, a storage module 8, and a search module 9.

[0096] The cyclotron 1 has a first outlet end and a second outlet end arranged opposite along a length direction, and is configured to accommodate the first ion source 2 and the second ion source 3 arranged opposite along the length direction. The cyclotron 1 is capable of simultaneously introducing, accelerating, and leading out protons generated by the first ion source 2 and the second ion source 3.

[0097] The debugging module 7 is configured to set a preset step length, and control the first driving assembly 4 to drive the first ion source 2 to move along the axial direction away from the second ion source 3 according to the preset step length, and control the second driving assembly 5 to drive the second ion source 3 to move along the axial direction away from the first ion source 2 according to the preset step length. For example, the preset step length can be 0.2 mm.

[0098] The first driving assembly 4 has a fixed end and a driving end. The fixed end of the first driving assembly 4 is connected to the first outlet end of the cyclotron 1, and the driving end of the first driving assembly 4 is connected to the first ion source 2. The first driving assembly 4 is configured to drive the first ion source 2 to move along the axial direction away from the second ion source 3 according to the preset step length. Specifically, the first ion source 2 is moved from a first initial position to a first maximum target position. For example, the first initial position can be 0 mm along the X-axis, and the first maximum target position can be 1 mm along the X-axis.

[0099] The second driving assembly 5 has a fixed end and a driving end. The fixed end of the second driving assembly 5 is connected to the second outlet end of the cyclotron 1, and the driving end of the second driving assembly 5 is connected to the second ion source 3. The second driving assembly 5 is configured to drive the second ion source 3 to move along the axial direction away from the first ion source 2 according to the preset step length. Specifically, the second ion source 3 is moved from a second initial position to a second maximum target position. For example, the second initial position can be 0 mm along the X-axis, and the second maximum target position can be -1 mm along the X-axis.

[0100] It should be noted that the first initial position and the first maximum target position are the limit positions of the first ion source 2, and the second initial position and the second maximum target position are the limit positions of the second ion source 3.

[0101] Specifically, in the embodiment, referring to FIG. 6, the first ion source 2 and the second ion source 3 are not in contact with each other, and a minimum installation gap is arranged between the first initial position of the first ion source 2 and the second initial position of the second ion source 3. The minimum installation gap is 0.508 mm, which has a great influence on the beam intensity, is suitable for the first ion source and the second ion source to be adjusted to a suitable position, and is easy to ensure the generation of the maximum beam intensity.

[0102] Specifically, in the embodiment, the position moving distance of the first ion source 2 from the first initial position to the first maximum target position and the position moving distance of the second ion source 3 from the second initial position to the second maximum target position are both not more than 1 mm.

[0103] The axial distance from the first initial position to the first maximum target position and the axial distance from the second initial position to the second maximum target position can be configured to be equal or unequal.

[0104] In the embodiment, the first driving assembly 4 and the second driving assembly 5 are preferably of the same specification, have the same shape and structure, and can be configured to be symmetrical relative to the center of the cyclotron 1. The first ion source 2 at the first initial position and the second ion source 3 at the second initial position are configured to be symmetrical relative to the center of the cyclotron 1. The first ion source 2 at the first maximum target position and the second ion source 3 at the second maximum target position are configured to be symmetrical relative to the center of the cyclotron 1.

[0105] The recording module 6 is connected (which can be a communication connection, including wired connection or wireless connection) with the first driving assembly 4 and the second driving assembly 5 respectively. The recording module 6 is used to record all the first positions of the first ion source 2 from the first initial position to the first maximum target position and all the second positions of the second ion source 3 from the second initial position to the second maximum target position respectively, and combine each first position with each second position to obtain all position combinations.

[0106] It can be understood that the first ion source 2 moves once according to a preset step length of 0.2 mm each time, and the recording module 6 records a position once. All the first positions include 0 mm (the first initial position), 0.2 mm, 0.4 mm, 0.6 mm, 0.8 mm, and 1 mm (the first maximum target position) in the X axial direction. The second ion source 3 moves once according to a preset step length of 0.2 mm each time, and the recording module 6 records a position once. All the second positions include 0 mm (the second initial position), -0.2 mm, -0.4 mm, -0.6 mm, -0.8 mm, and -1 mm (the second maximum target position) in the X axial direction.

[0107] All position combinations include (0mm, 0mm), (0mm, -0.2mm), (0mm, -0.4mm), (0mm, -0.6mm), (0mm, -0.8mm), (0mm, -1mm); (0.2mm, 0mm), (0.2mm, -0.2mm), (0.2mm, -0.4mm), (0.2mm, -0.6mm), (0.2mm, -0.8mm), (0.2mm, -1mm); (0.4mm, 0mm), (0.4mm, -0.2mm), (0.4mm, -0.4mm), (0.4mm, -0.6mm), (0.4mm, -0.8mm), (0.4mm, -1mm); (0.6mm, 0mm), (0.6mm, -0.2mm), (0.6mm, -0.4mm), (0.6mm, -0.6mm), (0.6mm, -0.8mm), (0.6mm, -1mm); (0.8mm, 0mm), (0.8mm, -0.2mm), (0.8mm, -0.4mm), (0.8mm, -0.6mm), (0.8mm, -0.8mm), (0.8mm, -1mm); (1mm, 0mm), (1mm, -0.2mm), (1mm, -0.4mm), (1mm, -0.6mm), (1mm, -0.8mm), (1mm, -1mm), wherein the first data in each bracket is the first position and the second data is the second position.

[0108] The debugging module 7 is also configured to control the cyclotron 1 to emit a proton beam at each position combination, i.e., to deliver a proton beam, so that the cyclotron 1 simultaneously performs the operations of introducing, accelerating and emitting the protons generated by the first ion source 2 and the second ion source 3 into the cyclotron orbit in sequence.

[0109] The storage module 8 is configured to obtain a beam intensity corresponding to each position combination, store each beam intensity, and form a data set including all beam intensities. The beam intensity is measured by a Faraday cup electrometer (not shown in the figure) arranged in the cyclotron 1.

[0110] The searching module 9 is configured to search for a maximum beam intensity from the data set, wherein the maximum beam intensity corresponds to an optimal position combination of the cyclotron 1, and the optimal position combination includes an optimal first position of the first ion source 2 and an optimal second position of the second ion source 3.

[0111] The embodiment provides a relatively symmetrical electric field by arranging two ion sources, i.e., the first ion source 2 and the second ion source 3, ensures that the electric field is large enough, and the first ion source 2 and the second ion source 3 can simultaneously form sufficient plasma to generate sufficient protons, facilitating searching for maximum beam intensity; the remote automatic adjustment of the ion source position is realized by controlling the first driving assembly 4 to adjust the position of the first ion source 2 and the second driving assembly 5 to adjust the position of the second ion source 3 according to a preset step length, so that the radiation safety problem and waiting time caused by the adjustment of the ion source position in the cylinder of the cyclotron by the debugging personnel each time entering the machine room and rotating the gantry are not considered, the debugging personnel are prevented from being exposed to radiation, and the beam debugging efficiency is improved; the beam debugging accuracy and the debugging efficiency are improved through the automatic adjustment of the ion source position and the automatic search for the maximum beam intensity.

[0112] In an implementation manner, referring to FIGS. 4A-5B, the first driving assembly 4 includes a first connecting frame 40, a first servo motor 41, a first transmission shaft 42, a first ball screw 44, a first bearing seat 46, a second bearing seat 47, and a first shaft sleeve assembly 48.

[0113] The first connecting frame 40 has opposite first and second ends.

[0114] The first servo motor 41 has a fixed end and a driving end, and the fixed end of the first servo motor 41 is connected to the first end of the first connecting frame 40. The first servo motor 41 can adopt an absolute encoder, the value of the encoder is directly converted into a position reading (which can be feet), and the first initial position of the first ion source 2 and all the first positions of the first ion source 2 moving at a preset step length can be accurately recorded.

[0115] The first transmission shaft 42 has opposite first and second ends, and the first end of the first transmission shaft 42 is connected to the driving end of the first servo motor 41 through the first coupling 43.

[0116] The first ball screw 44 has opposite first and second ends, and the first end of the first ball screw 44 is connected to the second end of the first transmission shaft 42 through the second coupling 45.

[0117] The first bearing seat 46 is arranged on the first connecting frame 40 and away from the second end of the first connecting frame 40, the first bearing seat 46 is sleeved on the first ball screw 44 and connected with the first ball screw 44, and located near the first end of the first ball screw 44.

[0118] The second bearing seat 47 is arranged on the first connecting frame 40 and close to the second end of the first connecting frame 40, the second bearing seat 47 is sleeved on the first ball screw 44 and connected with the first ball screw 44, and located near the second end of the first ball screw 44.

[0119] The first shaft sleeve assembly 48 is sleeved on the first transmission shaft 42 and connected with the first ball screw 44, and is located between the first bearing seat 46 and the second bearing seat 47. The first shaft sleeve assembly 48 is connected with the first ion source 2.

[0120] The distance between the first bearing seat 46 and the second bearing seat 47 is configured as 55 mm, and the effective range of the first ball screw 44 is configured as 54 mm.

[0121] The working process of the first driving assembly 4 is as follows: the first servo motor 41 drives the first transmission shaft 42 to rotate through the first shaft coupling 43, and the first transmission shaft 42 drives the first ball screw 44 to rotate through the second shaft coupling 45, so that the first shaft sleeve assembly 48 on the first ball screw 44 drives the first ion source 2 to move in the X-axis direction, that is, the rotary motion of the first servo motor 41 is converted into the linear motion of the first shaft sleeve assembly 48, so as to realize the position adjustment of the first ion source 2.

[0122] In an implementation manner, the second driving assembly 5 includes a second connecting frame 50, a second servo motor 51, a second transmission shaft 52, a second ball screw 54, a third bearing seat 56, a fourth bearing seat 57, and a second shaft sleeve assembly 58.

[0123] The second connecting frame 50 has opposite first and second ends.

[0124] The second servo motor 51 has a fixed end and a driving end, and the fixed end of the second servo motor 51 is connected with the first end of the second connecting frame 50. The second servo motor 51 and the first servo motor 41 are of a unified specification, and can adopt an absolute encoder. The value of the encoder is directly converted into a position reading (which can be in feet), and can accurately record the second initial position of the second ion source 3 and all second positions of the second ion source 3 moving at a preset step length.

[0125] The second transmission shaft 52 has opposite first and second ends, and the first end of the second transmission shaft 52 is connected with the driving end of the second servo motor 51 through a third shaft coupling 53.

[0126] The second ball screw 54 has opposite first and second ends, and the first end of the second ball screw 54 is connected with the second end of the second transmission shaft 52 through a fourth shaft coupling 55.

[0127] The third bearing seat 56 is arranged on the second connecting frame 50 and away from the second end of the second connecting frame 50. The third bearing seat 56 is sleeved on the second ball screw 54 and connected with the second ball screw 54, and is located near the first end of the second ball screw 54.

[0128] The fourth bearing seat 57 is arranged on the second connecting frame 50 and close to the second end of the second connecting frame 50, the fourth bearing seat 57 is sleeved on the second ball screw 54 and connected with the second ball screw 54, and is located close to the second end of the second ball screw 54.

[0129] The second shaft sleeve assembly 58 is sleeved on the second ball screw 54 and connected with the second ball screw 54, and is located between the third bearing seat 56 and the fourth bearing seat 57, the second shaft sleeve assembly 58 is connected with the second ion source 3.

[0130] Wherein, the distance between the third bearing seat 56 and the fourth bearing seat 57 can be configured as 55mm, and the effective range of the second ball screw 54 can be configured as 54mm.

[0131] The working process of the second driving assembly 5 is as follows: the second servo motor 51 drives the second transmission shaft 52 to rotate through the third coupling 53, the second transmission shaft 52 drives the second ball screw 54 to rotate through the fourth coupling 55, so that the second shaft sleeve assembly 58 on the second ball screw 54 drives the second ion source 3 to move in the X-axis direction, that is, the rotary motion of the second servo motor 51 is converted into the linear motion of the second shaft sleeve assembly 58, so as to realize the position adjustment of the second ion source 3.

[0132] In an implementation manner, the first connecting frame 40 is L-shaped, including a first horizontal plate 400 and a first vertical plate 401.

[0133] The first horizontal plate 400 has a first surface and a second surface arranged opposite in the thickness direction, one end of the first horizontal plate 400 is connected with the fixed end of the first servo motor 41, and the first bearing seat 46 and the second bearing seat 47 are both arranged on the first surface of the first horizontal plate 400.

[0134] The first vertical plate 401 has a first end and a second end, the first end of the first vertical plate 401 is connected with the second surface of the first horizontal plate 400 perpendicularly, and the second end of the first vertical plate 401 is connected with the first outlet end of the cyclotron 1.

[0135] The first connecting frame 40 further includes a first reinforcing plate 402, the first reinforcing plate 402 is triangular, the first reinforcing plate 402 has a first surface and a second surface perpendicular to each other, the first surface of the first reinforcing plate 402 is connected with the second surface of the first horizontal plate 400, and the second surface of the first reinforcing plate 402 is connected with one surface of the first vertical plate 401.

[0136] The first reinforcing plate 402 improves the connection stability of the first horizontal plate 400 and the first vertical plate 401, ensures the overall stability of the first connecting frame 40, and guarantees the accurate position adjustment of the first driving assembly 4 during the position movement of the first ion source 2.

[0137] In an implementation, the second connecting frame 50 is L-shaped, comprising a second horizontal plate 500 and a second vertical plate 501.

[0138] The second horizontal plate 500 has a first face and a second face oppositely arranged along the thickness direction, one end of the second horizontal plate 500 is connected with the fixed end of the second servo motor 51, and the third bearing seat 56 and the fourth bearing seat 57 are both arranged on the first face of the second horizontal plate 500.

[0139] The second vertical plate 501 has a first end and a second end, the first end of the second vertical plate 501 is connected with the second face of the second horizontal plate 500 perpendicularly, and the second end of the second vertical plate 501 is connected with the second outlet end of the cyclotron 1.

[0140] The second connecting frame 50 further comprises a second reinforcing plate 502, the second reinforcing plate 502 is triangular, the second reinforcing plate 502 has a first face and a second face perpendicularly arranged, the first face of the second reinforcing plate 502 is connected with the second face of the second horizontal plate 500, and the second face of the second reinforcing plate 502 is connected with one face of the second vertical plate 501.

[0141] The second reinforcing plate 502 improves the connection stability of the second horizontal plate 500 and the second vertical plate 501, ensures the overall stability of the second connecting frame 50, and guarantees the accurate position adjustment of the second ion source 3 during the position movement driven by the second driving assembly 5.

[0142] In an implementation, referring to FIG. 5B, the first shaft sleeve assembly 48 comprises a first nut sleeve 480, a first fixed sleeve 481 and a first side fixing piece 482.

[0143] The first nut sleeve 480 is sleeved on the first ball screw 44 and connected with the first ball screw 44.

[0144] The first fixed sleeve 481 is sleeved on the first nut sleeve 480, and the two ends of the first fixed sleeve 481 are respectively connected with the first side fixing piece 482.

[0145] The first side fixing piece 482 has a first end and a second end along the length direction, the first end of the first side fixing piece 482 is connected with the first fixed sleeve 481, and the second end of the first side fixing piece 482 is connected with the first ion source 2.

[0146] The first side fixing piece 482 improves the stability of the first ion source 2 during the movement, and guarantees the accurate position adjustment of the first ion source 2 during the position movement driven by the first driving assembly 4.

[0147] In an implementation, the second shaft sleeve assembly 58 comprises a second nut sleeve 580, a second fixed sleeve 581 and a second side fixing piece 582.

[0148] The second nut sleeve 580 is sleeved on the second ball screw 54 and connected with the second ball screw 54.

[0149] The second fixed sleeve 581 is sleeved on the second nut sleeve 580, and two ends of the second fixed sleeve 581 are respectively connected with the second side fixed part 582.

[0150] The second side fixed part 582 has a first end and a second end along the length direction, the first end of the second side fixed part 582 is connected with the second fixed sleeve 581, and the second end of the second side fixed part 582 is connected with the second ion source 3.

[0151] The stability of the second ion source 3 during movement is improved, and the accurate adjustment of the position of the second ion source 3 during the position movement driven by the second driving assembly 5 is ensured.

[0152] It should be noted that the channel for accommodating the first ion source 2 and the second ion source 3 in the cyclotron 1 can limit the rotation of the first ion source 2 and the second ion source 3 with the first transmission shaft 42 and the second transmission shaft 52, and only allow the first ion source 2 and the second ion source 3 to perform linear motion.

[0153] Referring to FIG. 8, the embodiment further provides a cyclotron maximum beam intensity automatic search method applied to the cyclotron maximum beam intensity automatic search system of the embodiment, and the method comprises steps S1-S6.

[0154] Step S1: setting a preset step size, and the preset step size is related to the control accuracy of the first driving assembly 4 and the second driving assembly 5.

[0155] Step S2: controlling the first driving assembly 4 to drive the first ion source 2 to move from the first initial position to the first maximum target position and the second driving assembly 5 to drive the second ion source 3 to move from the second initial position to the second maximum target position according to the preset step size. The control can be synchronous control or asynchronous control, and the position diagram of the first ion source 2 and the second ion source 3 is shown in FIG. 6.

[0156] Step S3: recording all first positions in the process that the first ion source 2 moves from the first initial position to the first maximum target position and all second positions in the process that the second ion source 3 moves from the second initial position to the second maximum target position, and combining each first position with each second position to obtain all position combinations. The recording can be synchronous recording or asynchronous recording.

[0157] Step S4: controlling the cyclotron 1 to perform beam emission under each position combination, so that the cyclotron 1 simultaneously performs the introduction, acceleration and emission of protons generated by the first ion source 2 and the second ion source 3.

[0158] Step S5: Obtain the beam intensity corresponding to each position combination, store each beam intensity to form a data set including all beam intensities. Optionally, the data set can be stored in an Excel table.

[0159] Step S6: Search for the maximum beam intensity from the data set, the maximum beam intensity corresponds to the optimal position combination, the optimal position combination includes the optimal first position of the first ion source 2 and the optimal second position of the second ion source 3. Optionally, the maximum beam intensity can be searched in the Excel table using the vlookup function in combination with the max function or the min function.

[0160] In an implementation, the preset step size includes a coarse adjustment step size and a fine adjustment step size, and when the coarse adjustment step size 0.02mm is greater than the fine adjustment step size 0.005mm, the method includes a coarse adjustment stage and a fine adjustment stage.

[0161] Coarse adjustment stage: control the first driving assembly 4 to move the first ion source 2 from the first initial position to the first preset position and control the second driving assembly 5 to move the second ion source 3 from the second initial position to the second preset position according to the coarse adjustment step size.

[0162] Record all first positions in the process of moving the first ion source 2 from the first initial position to the first preset position and all second positions in the process of moving the second ion source 3 from the second initial position to the second preset position, and combine each first position with each second position to obtain all first position combinations.

[0163] Control the cyclotron 1 to perform beam emission under each first position combination, so that the cyclotron 1 simultaneously performs introduction, acceleration and introduction of protons generated by the first ion source 2 and the second ion source 3 in turn.

[0164] Obtain the first beam intensity corresponding to each first position combination, store each first beam intensity to form a first data set including all first beam intensities.

[0165] Search for the maximum first beam intensity from the first data set.

[0166] Obtain the optimal first position combination corresponding to the maximum first beam intensity, the optimal first position combination includes the optimal first position of the first ion source 2 and the optimal second position of the second ion source 3.

[0167] Fine adjustment stage: control the first driving assembly 4 to move the first ion source 2 from the optimal first position to the third preset position and control the second driving assembly 5 to move the second ion source 3 from the optimal second position to the fourth preset position according to the fine adjustment step size.

[0168] record all third positions of the first ion source 2 moving from the optimal first position to the third preset position and all fourth positions of the second ion source 3 moving from the optimal second position to the fourth preset position, combine each third position with each fourth position to obtain all second position combinations.

[0169] control the cyclotron 1 to perform beam emission under each second position combination so that the cyclotron 1 simultaneously performs the introduction, acceleration and emission of protons generated by the first ion source 2 and the second ion source 3 in turn.

[0170] obtain a second beam intensity corresponding to each second position combination, and store each second beam intensity to form a second data set including all second beam intensities.

[0171] search for a maximum second beam intensity from the second data set.

[0172] obtain an optimal second position combination corresponding to the maximum second beam intensity, the optimal second position combination including an optimal third position of the first ion source 2 and an optimal fourth position of the second ion source 3.

[0173] In an implementation manner, the third preset position includes the first initial position or the first maximum target position, and the fourth preset position includes the second initial position or the second maximum target position.

[0174] It should be noted that the third preset position can also be any position between the first initial position and the first maximum target position, and the fourth preset position can also be any position between the second initial position and the second maximum target position, and the selection and adjustment of the third preset position and the fourth preset position are related to requirements.

[0175] In the embodiment, preferably, the third preset position is the first maximum target position, and the fourth preset position is the second maximum target position, wherein the first initial position and the first maximum target position are limit positions of the first ion source 2, and the second initial position and the second maximum target position are limit positions of the second ion source 3. The position diagram of the first ion source 2 and the second ion source 3 in the embodiment is shown in FIG. 7.

[0176] When protons generated by the first ion source 2 and the second ion source 3 enter the Faraday cup electrometer, a beam current is generated, and the corresponding beam intensity can be obtained by measuring the beam current.

[0177] Referring to Table 1, Table 1 is test data of all first positions, second positions and beam currents corresponding to first beam intensities in the coarse adjustment stage in the embodiment.

[0178] Table 1

[0179] From Table 1, it can be seen that the maximum first beam current is 0.400 nA, the optimal first position of the first ion source 2 is 0.175 feet, the optimal second position of the second ion source 3 is 0.155 feet, and the optimal first position combination is (0.175, 0.155).

[0180] Referring to Table 2, Table 2 is the test data of the beam current corresponding to all third positions, fourth positions and second beam currents in the fine adjustment stage in the embodiment.

[0181] Table 2

[0182] From Table 2, it can be seen that the maximum second beam current is 0.420 nA, the optimal third position of the first ion source 2 is 0.170 feet, the optimal fourth position of the second ion source 3 is 0.155 feet, and the optimal second position combination is (0.170, 0.155).

[0183] From Table 1 and Table 2, it can be seen that, compared with manual adjustment, remote automatic adjustment of the ion source positions can be realized only through the coarse adjustment stage, the maximum first beam current is searched, the optimal first beam position is obtained relatively quickly, the optimal first position of the first ion source 2 and the optimal second position of the second ion source 3 are obtained relatively accurately, the radiation of the debugging personnel is avoided, and the debugging efficiency and accuracy are improved, but the following problems exist: the coarse adjustment step is too large, the maximum first beam current corresponding to the maximum first beam current is not accurate, the optimal first position of the first ion source 2 and the optimal second position of the second ion source 3 are also not accurate, and the debugging accuracy is affected; the coarse adjustment step is too small, the amount of debugging data is greatly increased, the number of debugging is greatly increased, the beam debugging efficiency is affected, and the debugging efficiency and accuracy cannot be considered.

[0184] By setting the fine adjustment stage after the coarse adjustment stage, the coarse adjustment stage can reduce the amount of debugging data, narrow the search range of the maximum beam current, reduce the number of debugging, improve the beam debugging efficiency, quickly search the maximum first beam current corresponding to the maximum first beam current, obtain the optimal first position combination, and obtain the optimal first position of the first ion source 2 and the optimal second position of the second ion source 3; through the fine adjustment stage, the maximum second beam current corresponding to the maximum second beam current can be searched more accurately on the basis of the optimal first position combination, the optimal second position combination is obtained, the optimal third position of the first ion source 2 and the optimal fourth position of the second ion source 3 are found accurately and quickly, the debugging accuracy is improved, the debugging efficiency and accuracy are considered, compared with only through the coarse adjustment stage, the debugging efficiency and accuracy are further improved.

[0185] In order to further improve the search accuracy of the maximum beam intensity, the preset step can also be set as a first preset step, a second preset step, a third preset step, and an Nth preset step.

[0186] The embodiment also provides a radiotherapy device, which comprises the accelerator maximum flow intensity automatic search system and applies the accelerator maximum flow intensity automatic search method.

[0187] The accelerator maximum flow intensity automatic search system and method improve the debugging efficiency and accuracy, shorten the treatment time when treating the tumor of a patient with a proton beam in the future, ensure better radiotherapy effect, and make the proton therapy more popular.

Claims

1. An accelerator maximum beam intensity automatic search system, comprising: a cyclotron (1) having a first outlet end and a second outlet end arranged opposite along a length direction, for accommodating a first ion source (2) and a second ion source (3) arranged opposite along the length direction; a first driving assembly (4) having a fixed end connected with the first outlet end of the cyclotron (1) and a driving end connected with the first ion source (2), for driving the first ion source (2) to move axially away from the second ion source (3); a second driving assembly (5) having a fixed end connected with the second outlet end of the cyclotron (1) and a driving end connected with the second ion source (3), for driving the second ion source (3) to move axially away from the first ion source (2); a recording module (6) connected with the first driving assembly (4) and the second driving assembly (5) respectively, for recording all first positions of the first ion source (2) and all second positions of the second ion source (3) respectively, and combining each first position with each second position to obtain all position combinations; a debugging module (7) for setting a preset step, controlling the first driving assembly (4) to drive the first ion source (2) to move according to the preset step, and controlling the second driving assembly (5) to drive the second ion source (3) to move according to the preset step; the debugging module controls the cyclotron (1) to emit beam under each position combination, so that the cyclotron (1) simultaneously introduces, accelerates and emits protons generated by the first ion source (2) and the second ion source (3); a storage module (8) for obtaining beam intensity corresponding to each position combination, and storing each beam intensity to form a data set including all beam intensities; a search module (9) for searching a maximum beam intensity from the data set, the maximum beam intensity corresponding to an optimal position combination, the optimal position combination including an optimal first position of the first ion source (2) and an optimal second position of the second ion source (3).

2. The accelerator maximum current automatic search system according to claim 1, wherein The first ion source (2) and the second ion source (3) are not in contact, and a minimum installation gap is arranged between a first initial position of the first ion source (2) and a second initial position of the second ion source (3), the minimum installation gap being 0.508 mm, and the position moving distance of the first ion source (2) from the first initial position to a first maximum target position and the position moving distance of the second ion source (3) from the second initial position to a second maximum target position are both not more than 1 mm.

3. The accelerator maximum current automatic search system according to claim 1, wherein The first driving assembly (4) comprises: a first connecting frame (40) having opposite first and second ends; The first servo motor (41) has a fixed end and a driving end, and the fixed end of the first servo motor (41) is connected with the first end of the first connecting frame (40); The first transmission shaft (42) has opposite first and second ends, and the first end of the first transmission shaft (42) is connected with the driving end of the first servo motor (41) through the first coupling (43); The first ball screw (44) has opposite first and second ends, and the first end of the first ball screw (44) is connected with the second end of the first transmission shaft (42) through the second coupling (45); The first bearing seat (46) is arranged on the first connecting frame (40) and away from the second end of the first connecting frame (40), the first bearing seat (46) is sleeved on and connected with the first ball screw (44), and is located near the first end of the first ball screw (44); The second bearing seat (47) is arranged on the first connecting frame (40) and close to the second end of the first connecting frame (40), the second bearing seat (47) is sleeved on and connected with the first ball screw (44), and is located near the second end of the first ball screw (44); The first bearing sleeve assembly (48) is sleeved on and connected with the first ball screw (44), and is located between the first bearing seat (46) and the second bearing seat (47), and the first bearing sleeve assembly (48) is connected with the first ion source (2).

4. The accelerator maximum current automatic search system according to claim 1, wherein The second driving assembly (5) comprises: The second connecting frame (50) has opposite first and second ends; The second servo motor (51) has a fixed end and a driving end, and the fixed end of the second servo motor (51) is connected with the first end of the second connecting frame (50); The second transmission shaft (52) has opposite first and second ends, and the first end of the second transmission shaft (52) is connected with the driving end of the second servo motor (51) through the third coupling (53); The second ball screw (54) has opposite first and second ends, and the first end of the second ball screw (54) is connected with the second end of the second transmission shaft (52) through the fourth coupling (55); The third bearing seat (56) is arranged on the second connecting frame (50) and away from the second end of the second connecting frame (50), the third bearing seat (56) is sleeved on and connected with the second ball screw (54), and is located near the first end of the second ball screw (54); The fourth bearing seat (57) is arranged on the second connecting frame (50) and close to the second end of the second connecting frame (50), the fourth bearing seat (57) is sleeved on and connected with the second ball screw (54), and is located near the second end of the second ball screw (54); A second shaft sleeve assembly (58) is sleeved on and connected with the second ball screw (54) and is located between the third bearing seat (56) and the fourth bearing seat (57), and the second shaft sleeve assembly (58) is connected with the second ion source (3).

5. The accelerator maximum current automatic search system according to claim 3, wherein The first connecting frame (40) is L-shaped and comprises: A first horizontal plate (400) has a first face and a second face arranged opposite in the thickness direction, one end of the first horizontal plate (400) is connected with the fixed end of the first servo motor (41), and the first bearing seat (46) and the second bearing seat (47) are arranged on the first face of the first horizontal plate (400); A first vertical plate (401) has a first end and a second end, the first end of the first vertical plate (401) is connected with the second face of the first horizontal plate (400) perpendicularly, and the second end of the first vertical plate (401) is connected with the first outlet end of the cyclotron (1); A first reinforcing plate (402) has a first face and a second face arranged perpendicularly, the first face of the first reinforcing plate (402) is connected with the second face of the first horizontal plate (400), and the second face of the first reinforcing plate (402) is connected with one face of the first vertical plate (401).

6. The accelerator maximum current automatic search system according to claim 4, wherein The second connecting frame (50) is L-shaped and comprises: A second horizontal plate (500) has a first face and a second face arranged opposite in the thickness direction, one end of the second horizontal plate (500) is connected with the fixed end of the second servo motor (51), and the third bearing seat (56) and the fourth bearing seat (57) are arranged on the first face of the second horizontal plate (500); A second vertical plate (501) has a first end and a second end, the first end of the second vertical plate (501) is connected with the second face of the second horizontal plate (500) perpendicularly, and the second end of the second vertical plate (501) is connected with the second outlet end of the cyclotron (1); A second reinforcing plate (502) has a first face and a second face arranged perpendicularly, the first face of the second reinforcing plate (502) is connected with the second face of the second horizontal plate (500), and the second face of the second reinforcing plate (502) is connected with one face of the second vertical plate (501).

7. The accelerator maximum current automatic search system according to claim 3, wherein The first shaft sleeve assembly (48) comprises: A first nut sleeve (480) is sleeved on and connected with the first ball screw (44); A first fixed sleeve (481) is sleeved on the first nut sleeve (480), and both ends of the first fixed sleeve (481) are respectively connected with first side fixing members (482); A first side fixing member (482) has a first end and a second end along the length direction, the first end of the first side fixing member (482) is connected with the first fixed sleeve (481), and the second end of the first side fixing member (482) is connected with the first ion source (2).

8. The accelerator maximum current automatic search system according to claim 4, wherein The second shaft sleeve assembly (58) comprises: A second nut sleeve (580) is sleeved on and connected with the second ball screw (54); A second fixed sleeve (581) is sleeved on the second nut sleeve (580), and two ends of the second fixed sleeve (581) are respectively connected with second side fixing members (582); The second side fixing member (582) has a first end and a second end in the length direction, the first end of the second side fixing member (582) is connected with the second fixed sleeve (581), and the second end of the second side fixing member (582) is connected with the second ion source (3).

9. An accelerator maximum beam intensity automatic search method applied to the accelerator maximum beam intensity automatic search system of any one of claims 1-8, the method comprising: setting the preset step length; controlling the first driving assembly (4) to drive the first ion source (2) to move from the first initial position to the first maximum target position and the second driving assembly (5) to drive the second ion source (3) to move from the second initial position to the second maximum target position according to the preset step length; recording all first positions in the process that the first ion source (2) moves from the first initial position to the first maximum target position and all second positions in the process that the second ion source (3) moves from the second initial position to the second maximum target position, combining each first position with each second position to obtain all position combinations; controlling the cyclotron (1) to emit beams under each position combination, so that the cyclotron (1) sequentially performs introduction, acceleration and emission on protons generated by the first ion source (2) and the second ion source (3); obtaining beam intensities corresponding to each position combination, storing each beam intensity to form a data set including all beam intensities; searching for a maximum beam intensity from the data set, the maximum beam intensity corresponding to an optimal position combination, and the optimal position combination including an optimal first position of the first ion source (2) and an optimal second position of the second ion source (3).

10. The accelerator maximum current automatic search method according to claim 9, wherein The distance from the first initial position to the first maximum target position and the distance from the second initial position to the second maximum target position can be configured to be equal or unequal.

11. The accelerator maximum current automatic search method according to claim 10, wherein The preset step length includes a coarse adjustment step length and a fine adjustment step length, the coarse adjustment step length is greater than the fine adjustment step length, and the method comprises: coarse adjustment stage: controlling the first driving assembly (4) to drive the first ion source (2) to move from the first initial position to a first preset position and the second driving assembly (5) to drive the second ion source (3) to move from the second initial position to a second preset position according to the coarse adjustment step length; recording all first positions in the process that the first ion source (2) moves from the first initial position to the first preset position and all second positions in the process that the second ion source (3) moves from the second initial position to the second preset position, combining each first position with each second position to obtain all first position combinations; controlling the cyclotron (1) to emit beams under each first position combination, so that the cyclotron (1) sequentially performs introduction, acceleration and emission on protons generated by the first ion source (2) and the second ion source (3) at the same time; obtaining a first beam intensity corresponding to each first position combination, storing each first beam intensity to form a first data set including all first beam intensities; searching for a maximum first beam intensity from the first data set; obtaining an optimal first position combination corresponding to the maximum first beam intensity, the optimal first position combination including an optimal first position of the first ion source (2) and an optimal second position of the second ion source (3) corresponding thereto; a fine tuning stage: controlling the first driving assembly (4) to move the first ion source (2) from the optimal first position to a third preset position according to the fine tuning step, and controlling the second driving assembly (5) to move the second ion source (3) from the optimal second position to a fourth preset position according to the fine tuning step; recording all third positions in the process of moving the first ion source (2) from the optimal first position to the third preset position, and recording all fourth positions in the process of moving the second ion source (3) from the optimal second position to the fourth preset position, combining each third position with each fourth position to obtain all second position combinations; controlling the cyclotron (1) to emit beams under each second position combination, so that the cyclotron (1) sequentially performs introduction, acceleration and emission on protons generated by the first ion source (2) and the second ion source (3) at the same time; obtaining a second beam intensity corresponding to each second position combination, storing each second beam intensity to form a second data set including all second beam intensities; searching for a maximum second beam intensity from the second data set; obtaining an optimal second position combination corresponding to the maximum second beam intensity, the optimal second position combination including an optimal third position of the first ion source (2) and an optimal fourth position of the second ion source (3) corresponding thereto.

12. The accelerator maximum current automatic search method according to claim 11, wherein The preset steps include a first step, a second step,..., and an Nth step, and the first step > the second step >... > the Nth step.

13. The accelerator maximum current automatic search method according to claim 11, wherein The third preset position includes a first initial position or a first maximum target position, and the fourth preset position includes a second initial position or a second maximum target position.

14. A radiotherapy device, comprising the accelerator maximum beam intensity automatic search system according to any one of claims 1-8, and the accelerator maximum beam intensity automatic search method according to any one of claims 9-13.

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