Automatic target changing system and neutron capture treatment system

Abstract

The present application provides an automatic target changing system and a neutron capture treatment system. The automatic target changing system comprises: a shielding-type container, wherein the shielding-type container comprises a box body and a first guiding mechanism arranged on the box body; a second guiding mechanism, wherein the second guiding mechanism and the first guiding mechanism are configured to guide a target assembly to move; and a releasable device, wherein the first guiding mechanism can be connected to the second guiding mechanism by means of the releasable device, and when the target assembly moves to a preset position, the releasable device is configured to disconnect the connection between the first guiding mechanism and the second guiding mechanism. When the target assembly moves to the preset position, the releasable device can separate the first guiding mechanism from the second guiding mechanism, so that automatic separation of the shielding-type container and other parts is realized, thereby facilitating the recycling of the target assembly, especially the recycling of a target material.

Description

Automatic target changing system and neutron capture therapy system Technical Field

[0001] This application relates to the field of automatic target changing, and more particularly to an automatic target changing system and a neutron capture therapy system. Background Technology

[0002] With the development of atomic science, radiation therapy, such as cobalt-60, linear accelerators, and electron beams, has become one of the main methods of cancer treatment. However, traditional photon or electron therapy is limited by the physical conditions of radiation itself. While killing tumor cells, it also damages a large amount of normal tissue along the beam path. In addition, due to the different sensitivities of tumor cells to radiation, traditional radiation therapy is often ineffective for more radiation-resistant malignant tumors (such as glioblastoma multiforme and melanoma).

[0003] To reduce radiation damage to surrounding normal tissues, the concept of targeted therapy in chemotherapy has been applied to radiotherapy. Furthermore, for highly radiation-resistant tumor cells, radiation sources with high relative biological effectiveness (RBE) are being actively developed, such as proton therapy, heavy ion therapy, and neutron capture therapy. Neutron capture therapy combines these two concepts; for example, boron neutron capture therapy utilizes the specific accumulation of boron-containing drugs on tumor cells, combined with precise neutron beam modulation, to provide a better cancer treatment option than traditional radiation.

[0004] In a neutron capture therapy system, a charged particle beam is accelerated by an accelerator to an energy sufficient to overcome the Coulomb repulsion of the target atomic nuclei within the beam shaper. The charged particle beam then undergoes a nuclear reaction with the target to produce neutrons, which are then modulated in the energy spectrum of the beam shaper (BSA) for therapeutic use. Because the target assembly used to produce neutrons has a limited lifespan, it needs to be replaced regularly to ensure stable neutron production.

[0005] Practice has shown that existing neutron capture therapy systems, especially existing automatic target-changing systems, may generate some radiation for operators during the target-changing process, thus there is considerable room for improvement. Summary of the Invention

[0006] Based on the aforementioned deficiencies in the prior art, the automatic target-changing system and neutron capture therapy system of this application have better performance.

[0007] To achieve the above objectives, the first aspect of this application provides an automatic target changing system for replacing target components, comprising:

[0008] A shielded container, the shielded container including a box and a first guide mechanism disposed on the box;

[0009] A second guiding mechanism, the second guiding mechanism and the first guiding mechanism are configured to guide the movement of the target component;

[0010] A releasable device is provided, wherein the first guide mechanism can be connected to the second guide mechanism via the releasable device, and when the target component moves to a preset position, the releasable device is configured to disconnect the connection between the first guide mechanism and the second guide mechanism.

[0011] As a preferred embodiment, the releasable device includes a latching portion and a moving portion, the moving portion being movable relative to the latching portion, thereby connecting or disengaging the moving portion from the latching portion, wherein the latching portion is disposed on the second guide mechanism and the moving portion is disposed on the first guide mechanism; or, the latching portion is disposed on the first guide mechanism and the moving portion is disposed on the second guide mechanism.

[0012] As a preferred embodiment, when the target component moves to the preset position, the target component abuts against the moving part, thereby driving the moving part to move relative to the latching part to disconnect the connection between the first guide mechanism and the second guide mechanism.

[0013] As a preferred embodiment, the target assembly includes a bracket and a target material, the target material being radioactive, the bracket being used to carry the target material and being movable along the second guide mechanism and the first guide mechanism, the bracket having a first end and a second end opposite to each other, the target material being disposed at the first end of the bracket, and the second end of the bracket being able to abut against the moving part, thereby driving the moving part to move relative to the latching part to disconnect the connection between the first guide mechanism and the second guide mechanism.

[0014] As a preferred embodiment, the releasable device further includes a transmission component, wherein when the target assembly moves to a preset position, the releasable device is configured to disengage the moving part from the latching part via the transmission component.

[0015] As a preferred embodiment, the shielded container further includes a second buffer device disposed within the shielded container, wherein the preset position is the position where the target assembly moves along the first guide mechanism to contact the second buffer device.

[0016] As a preferred embodiment, during the movement of the target assembly along the second guide mechanism, the second end of the bracket is always closer to the shielded container than the first end of the bracket; the second end of the bracket enters the shielded container before the first end of the bracket.

[0017] As a preferred embodiment, when the first guide mechanism is connected to the second guide mechanism, at least a portion of the first guide mechanism is located outside the housing.

[0018] As a preferred embodiment, after the first guide mechanism is disconnected from the second guide mechanism, the first guide mechanism can move relative to the housing, thereby moving into the housing.

[0019] As a preferred embodiment, the target assembly includes a bracket and a target material disposed on the bracket;

[0020] The surface of the second guide mechanism that supports the bracket is configured as a guide surface. The guide surface extends continuously along the second guide mechanism, and the extension direction of the guide surface is consistent with the extension direction of the second guide mechanism. During the movement along the second guide mechanism, the target material is always located on the same side of the guide surface.

[0021] As a preferred embodiment, the bracket has a first end and a second end, the target material is disposed at the first end of the bracket, and during the movement of the target assembly on the second guide mechanism, the second end of the bracket is always closer to the housing than the first end of the bracket.

[0022] A second aspect of this application provides a neutron capture therapy system, the neutron capture therapy system comprising:

[0023] Accelerators are used to generate beams of charged particles.

[0024] Target assembly, including a target material that reacts with a charged particle beam to generate a neutron beam;

[0025] Beam shaper, used to modulate the energy spectrum of a neutron beam;

[0026] A shielded container includes a housing and a first guiding mechanism disposed on the housing;

[0027] A second guiding mechanism, the second guiding mechanism and the first guiding mechanism are configured to guide the movement of the target component;

[0028] A releasable device is provided, wherein the first guide mechanism can be connected to the second guide mechanism via the releasable device, and when the target component moves to a preset position, the releasable device is configured to disconnect the connection between the first guide mechanism and the second guide mechanism.

[0029] As a preferred embodiment, when the target component moves to the preset position, the target component drives the releasable device to disconnect the connection between the first guide mechanism and the second guide mechanism.

[0030] As a preferred embodiment, the releasable device includes a latching portion and a moving portion, the moving portion being movable relative to the latching portion, thereby enabling the moving portion to connect or disengage from the latching portion, wherein the latching portion is disposed on the second guide mechanism and the moving portion is disposed on the first guide mechanism; or, the latching portion is disposed on the first guide mechanism and the moving portion is disposed on the second guide mechanism.

[0031] A third aspect of this application provides an automatic target changing system for replacing target components, including:

[0032] A shielded container includes a housing and a first guiding mechanism disposed on the housing;

[0033] A second guiding mechanism, the second guiding mechanism and the first guiding mechanism are configured to guide the movement of the target assembly, wherein at least a portion of the extension direction of the second guiding mechanism is not consistent with the extension direction of the first guiding mechanism;

[0034] The first buffer device provides a buffering force to the target assembly as it moves along the second guide mechanism to the first guide mechanism.

[0035] Preferably, during the movement of the target assembly along the second guide mechanism to the first guide mechanism, the first buffer device can come into contact with the target assembly.

[0036] Preferably, during the movement of the target assembly along at least a portion of the first guide mechanism, the first buffer device provides a buffering force to the target assembly.

[0037] As a preferred embodiment, the shielded container further includes a second buffer device, which provides a buffering force to the target assembly as it moves along the first guide mechanism.

[0038] As a preferred embodiment, during the process of the target assembly entering the shielded container along the second guide mechanism and the first guide mechanism, a portion of the target assembly is configured to have an overlapping motion trajectory that interferes with the first buffer device as the target assembly moves, so that the first buffer device abuts against the target assembly.

[0039] As a preferred embodiment, the target assembly has a buffer braking part, the buffer braking part has a buffer braking surface, and the buffer braking surface is provided with at least two buffer braking positions; during the process of the target assembly entering the shielded container along the second guide mechanism and the first guide mechanism, the first buffer device sequentially abuts against each of the at least two buffer braking positions, and the at least two buffer braking positions that sequentially abut against the first buffer device form the mutually interfering overlapping motion trajectories.

[0040] Preferably, after the first buffer device comes into sequential contact with each of the at least two buffer braking positions, the first buffer device disengages from the target assembly.

[0041] As a preferred embodiment, the first buffer device includes a first motion unit and a second motion unit. The first motion unit is disposed on the housing and is movable relative to the housing. The second motion unit is disposed on the first motion unit and is movable relative to the first motion unit. The second motion unit is capable of contacting or disengaging from the target assembly.

[0042] Preferably, the first motion unit is movable along the extension direction of the first guide mechanism, and the second motion unit moves in a direction opposite to the extension direction of the first guide mechanism; or,

[0043] The second motion unit can move along the extension direction of the first guide mechanism, while the movement direction of the first motion unit is opposite to the extension direction of the first guide mechanism.

[0044] As a preferred embodiment, the first buffer device includes a support rod having a first end close to the direction of movement of the target assembly and a second end away from the direction of movement of the target assembly. The support rod has a preset rotation center located between its first end and second end. The first end of the support rod includes a support portion that abuts against the target assembly, and the second end of the support rod is connected to a power source.

[0045] As a preferred embodiment, the target assembly has a notch, and the support rod can detach from the target assembly through the notch.

[0046] The fourth aspect of this application provides a neutron capture therapy system, comprising:

[0047] Accelerators are used to generate beams of charged particles.

[0048] The target assembly includes a target material that reacts with the charged particle beam to generate a neutron beam;

[0049] A beam shaper for adjusting the energy spectrum of the neutron beam;

[0050] A shielded container includes a housing and a first guiding mechanism disposed on the housing;

[0051] A second guiding mechanism is configured to guide the movement of the target assembly, wherein the extension direction of the second guiding mechanism is not consistent with the extension direction of the first guiding mechanism.

[0052] The first buffer device provides a buffering force to the target assembly as it moves along the second guide mechanism to the first guide mechanism.

[0053] As a preferred embodiment, it also includes:

[0054] A releasable device is provided, wherein the first guide mechanism can be connected to the second guide mechanism via the releasable device, and when the target component moves to a preset position, the releasable device is configured to disconnect the connection between the first guide mechanism and the second guide mechanism.

[0055] As a preferred embodiment, when the first guide mechanism is connected to the second guide mechanism, at least a portion of the first guide mechanism is located outside the housing; after the first guide mechanism is disconnected from the second guide mechanism, the first guide mechanism can move relative to the housing into the housing. Beneficial effects:

[0056] Using the above technical solution, when the target assembly moves to a preset position, the releasable device can separate the first guide mechanism from the second guide mechanism, thereby achieving automatic separation of the shielded container and other components to facilitate the recovery of the target assembly (especially the target material). During the change of the target assembly's movement direction, the first buffer device can provide a buffering force to the target assembly, thus protecting it.

[0057] Specific embodiments of this application are disclosed in detail with reference to the following description and accompanying drawings, illustrating how the principles of this application can be employed. It should be understood that the embodiments of this application are not limited in scope. Within the spirit and scope of the appended claims, the embodiments of this application include many changes, modifications, and equivalents.

[0058] Features described and / or illustrated for one embodiment may be used in the same or similar manner in one or more other embodiments, combined with features in other embodiments, or substituted for features in other embodiments.

[0059] It should be emphasized that the term "including / comprises" as used herein refers to the presence of a feature, whole, step, or component, but does not exclude the presence or addition of one or more other features, wholes, steps, or components. Attached Figure Description

[0060] The accompanying drawings described herein are for illustrative purposes only and are not intended to limit the scope of this application in any way. Furthermore, the shapes and scales of the components in the drawings are merely illustrative to aid in understanding this application and do not specifically limit the shapes and scales of the components. Those skilled in the art, guided by the teachings of this application, can select various possible shapes and scales to implement this application according to specific circumstances. In the drawings:

[0061] Figure 1 is a plan view of a neutron capture therapy system provided in an embodiment of the present invention.

[0062] Figure 2 is a three-dimensional schematic diagram of a neutron capture therapy system provided in an embodiment of the present invention.

[0063] Figure 3 is a schematic diagram of the shielding facility in the open state of a neutron capture therapy system provided in an embodiment of the present invention.

[0064] Figure 4 is a schematic diagram of the structure of the target component on the second guiding mechanism in a neutron capture therapy system provided by an embodiment of the present invention.

[0065] Figure 5 is a schematic diagram of the structure of a neutron capture therapy system provided in another embodiment of the present invention, showing the target component on the second guiding mechanism.

[0066] Figure 6 is a partially enlarged structural diagram of Figure 5.

[0067] Figure 7 is a partial structural diagram of the target component in a preset position in a neutron capture therapy system provided by an embodiment of the present invention.

[0068] Figure 8 is a schematic diagram of the first guiding mechanism in the retracted state in a neutron capture therapy system according to an embodiment of the present invention.

[0069] Figure 9 is a schematic diagram of the structure of the second guide section in a neutron capture therapy system provided in an embodiment of the present invention after pivoting relative to the first guide section.

[0070] Figure 10 is a schematic diagram of the structure of a shielded container in a neutron capture therapy system provided in an embodiment of the present invention.

[0071] Figure 11 is a schematic diagram of the structure of a shielded container in a neutron capture therapy system provided in another embodiment of the present invention.

[0072] Figure 12 is a schematic diagram of the structure of a neutron capture therapy system provided in an embodiment of the present invention, in which the target component is on the second guiding mechanism and is not in contact with the first buffer device.

[0073] Figure 13 is a schematic diagram of the structure of the first buffer device in the neutron capture therapy system provided by an embodiment of the present invention, which provides a buffering force to the target component.

[0074] Figure 14 shows a schematic diagram of the structure of a neutron capture therapy system provided by an embodiment of the present invention, in which the target component is located on a first guiding mechanism.

[0075] Figure 15 is a partially enlarged schematic diagram of Figure 14.

[0076] Figure 16 shows a first buffer device in a neutron capture therapy system provided in another embodiment of the present invention.

[0077] Figure 17 is a schematic diagram of the principle of Figure 16.

[0078] Figure 18 is a partial structural diagram of the contact area between the first buffer device and the target assembly.

[0079] Figure 19 is a schematic diagram of the structure of a releaseable device in a shielded container of a neutron capture therapy system provided in an embodiment of the present invention, wherein the moving part is driven by a transmission component.

[0080] Figure 20 is a partially enlarged schematic diagram of Figure 19.

[0081] The reference numerals in the above figures are as follows: 1. Charged particle beam generating device; 11. Accelerator; 12. Transmission device; 2. Target assembly; 21. Target material; 22. Bracket; 23. Buffer braking part; 231. Buffer braking surface; 2311. First buffer braking position; 2312. Second buffer braking position; 232. Notch; 24. Contact part; 3. Shielded container; 31. Box body; 311. Inner cavity; 32. First guide mechanism; 33. Cover plate assembly; 34. Drive part; 35. Opening and closing part; 36. Limiting track; 37. Offset track; 4. Guide device; 41. Second guide mechanism; 411. First guide part; 412. Second guide part; 5. 6. Beam shaping body; 7. Releaseable device; 8. Snap-on part; 9. Locking groove; 10. Moving part; 11. Locking pin; 12. Contact part; 13. Transmission component; 14. Drive rod; 15. Shielding facility; 16. Shielding door; 17. First opening; 18. First buffer device; 19. Power source; 10. Power mechanism; 10. First motion unit; 11. Second motion unit; 12. Support rod; 13. Preset rotation center; 14. Support part; 15. Second buffer device; 10. Guide column; 10. Rod body; R1. First space; R2. Second space; R3. Third space; X. Rotation direction; Y. First direction; Z. Second direction. Detailed Implementation

[0082] To enable those skilled in the art to better understand the technical solutions in this application, the technical solutions in the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort should fall within the scope of protection of this application.

[0083] It should be noted that when an element is referred to as being "set on" another element, it can be directly on the other element or there may be an intervening element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or there may be an intervening element. The terms "vertical," "horizontal," "left," "right," and similar expressions used herein are for illustrative purposes only and do not represent the only embodiments.

[0084] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0085] The various embodiments in this specification are described in a progressive manner. Similar or identical parts between embodiments can be referred to interchangeably. Each embodiment focuses on describing the differences from other embodiments. In particular, the system embodiments are basically similar to the method embodiments, so the description is relatively simple; relevant parts can be referred to the descriptions in the method embodiments.

[0086] It should be noted that in the description of this application, the terms "first," "second," etc., are used only for descriptive purposes and to distinguish similar objects; there is no order between them, nor should they be construed as indicating or implying relative importance. Furthermore, in the description of this application, unless otherwise stated, "multiple" means two or more.

[0087] Neutron capture therapy, as an effective treatment for cancer, has seen increasing application in recent years, with boron neutron capture therapy being the most common. Neutrons for boron neutron capture therapy can be supplied by a nuclear reactor or accelerator 11. This application's embodiments use accelerator-based boron neutron capture therapy as an example. The basic components of accelerator-based boron neutron capture therapy typically include an accelerator 11 for accelerating a beam of charged particles (such as protons, deuterons, etc.), a radioactive consumable target 21 and a thermal removal system, and a beam shaper 5. The accelerated charged particle beam interacts with the metal target 21 to produce neutrons. A suitable nuclear reaction is selected based on the required neutron yield and energy, the available energy and current of the accelerated charged particle beam, and the physicochemical properties of the metal target 21. Commonly discussed nuclear reactions include... 7 Li(p,n) 7 Be and 9 Be(p,n) 9 B. Both of these reactions are endothermic, with energy thresholds of 1.881 MeV and 2.055 MeV, respectively. Since the ideal neutron source for boron neutron capture therapy is hyperthermic neutrons at the keV energy level, theoretically, bombarding the lithium metal target 21 with protons with energies only slightly above the threshold could produce relatively low-energy neutrons, which could be used clinically without much slowing down. However, the interaction cross-section between lithium metal (Li) and beryllium metal (Be) targets 21 and protons at the threshold energy is not high. To generate a sufficiently large neutron flux, higher-energy protons are usually chosen to initiate the nuclear reaction.

[0088] An ideal radioactive consumable target 21 should possess characteristics such as high neutron yield, neutron energy distribution close to the hyperthermic neutron energy region, minimal strong penetration radiation, safety, low cost, ease of operation, and high temperature resistance. However, in reality, it is impossible to find a nuclear reaction that meets all these requirements. In the embodiments of this application, a target 21 made of lithium metal is used. However, as those skilled in the art will know, the target 21 can also be made of other metallic materials besides those discussed above.

[0089] After a certain period of use, the target material 21 needs to be replaced. This application aims to overcome the problems existing in the prior art when the target material needs to be replaced.

[0090] Referring to Figures 1, 2, and 3, the neutron capture therapy system may include a charged particle beam generating device 1, a target assembly 2, a beam shaper 5 (BSA), and a shielded container 3. The charged particle beam generating device 1 may include an accelerator 11 for generating a charged particle beam and a transmission device 12 for transmitting the charged particle beam. The transmission direction of the charged particle beam is consistent with or substantially consistent with the arrangement direction of the transmission device 12. The target assembly 2 can engage or disengage from the transmission device 12. When the target assembly 2 and the transmission device 12 are engaged, the charged particle beam output by the transmission device 12 can reach the target material 21. Referring to Figure 4, the target assembly 2 may include a bracket 22 whose extension direction is consistent with or substantially consistent with the transmission device. The bracket 22 has a first end and a second end opposite to each other along its extension direction. The radioactive target material 21 is located at the first end of the bracket 22.

[0091] Referring to Figures 2 and 3, the neutron capture therapy system can be divided into a first space R1 and a second space R2 based on a shielding facility 7 with opening and closing functions. The shielding facility 7 may include two shielding doors 71 that can move relative to each other. When the two shielding doors 71 are closed, the shielding facility 7 can form at least one first opening 72 through which the target assembly 2 and part of the transmission device 12 pass. In this embodiment, the first opening 72 is located at the transmission device 12, and the shape of the first opening 72 is adapted to the shape of the outer wall of the transmission device 12 through the first opening 72, including but not limited to circular, elliptical, rhomboid, square, irregular, and other shapes.

[0092] An accelerator 11 and a shielded container 3 are disposed within the first space R1. A beam shaper 5 is disposed within the second space R2. When the neutron capture therapy system is in radiotherapy mode, the first end of the target assembly 2 is engaged with the transmission device 12. At this time, the target assembly 2 is located within the second space R2. The transmission device 12 can transmit the charged particle beam accelerated by the accelerator 11 from the first space R1 to the target material 21 in the second space R2. The accelerator 11 accelerates the charged particle beam to an energy sufficient to overcome the Coulomb repulsion of the atomic nuclei of the target material 21, causing it to interact with the target material 21. 7 Li(p,n) 7The Be nuclear reaction produces neutrons, which form a neutron beam that exits from the beam shaper 5. The beam shaper 5, typically large in size, is embedded within the wall and includes a decelerator, reflector, thermal neutron absorber, and radiation shield (not shown in the attached figures). The decelerator is primarily made of aluminum fluoride, with optional materials such as lithium fluoride, aluminum, lead fluoride, alumina, calcium fluoride, or magnesium fluoride, or a mixture thereof. It slows the neutrons generated from the target 21 to the hyperthermal neutron energy region. Deviating neutrons are guided back to the decelerator by the reflector to increase the hyperthermal neutron flux. The thermal neutron absorber absorbs thermal neutrons to avoid unnecessary damage to superficial normal tissues due to excessive thermal neutron doses during treatment. The radiation shield is used to shield leaked neutrons and photons to reduce radiation to normal tissues in non-irradiated areas. The neutron capture therapy system further includes a third space R3 as an irradiation chamber, through which a neutron beam, shaped by a beam shaper, exits from the beam exit and enters the irradiation chamber for use.

[0093] When the target assembly 2 (target material 21) needs to be replaced, for example, after a certain period of use, a certain number of uses, or a malfunction of the target material 21, as shown in Figure 3, the target assembly 2 is detached from the transmission device 12. The target assembly 2 to be replaced is then moved from the second space R2 to the shielded container 3 in the first space R1 for recovery. Afterwards, the new target assembly 2 is transferred from the first space R1 to the second space R2, and then the target assembly 2 is reconnected to the transmission device 12. During the replacement of the target assembly 2, the transmission device 12 and the target assembly 2 are preferably kept under vacuum.

[0094] The neutron capture therapy system may also include a guide device 4 that provides support for the transport of the target assembly 2. The guide device 4 can connect to a second space R2 from a first space R1 through a first opening 72. Generally, the extension direction of the guide device 4 is parallel or substantially parallel to the transmission direction of the charged particle beam. The guide device 4 can be a single-piece construction. Of course, in other alternative embodiments, the guide device 4 can also be constructed as a separate component as needed. Although described as a track in this embodiment, the portion of the guide device 4 that mates with the bracket 22 can be configured as a channel, passageway, support, rail, pipe, or other structure.

[0095] Specifically, referring to Figures 4 and 5, the guiding device 4 may include a second guiding mechanism 41. The second guiding mechanism 41 may be disposed within the first space R1, or may extend from the second space R2 to the first space R1; the present invention does not limit this. The shielded container 3 may include a housing 31 and a first guiding mechanism 32. In the initial state, the first guiding mechanism 32 and the second guiding mechanism 41 are connected. The target assembly 2 can move along the second guiding mechanism 41 to the first guiding mechanism 31, thereby entering the housing 31 of the shielded container 3. For example, the target assembly 2 can move along the second guiding mechanism 41 from the position shown in Figure 4 to the position shown in Figure 5, and continue to move along the second guiding mechanism 41. The neutron capture therapy system may also include a release device 6. During the movement of the target assembly 2 from the second guide mechanism 41 to the first guide mechanism 32, when the target assembly 2 reaches a preset position (e.g., as shown in Figure 7), the release device 6 is configured to disconnect the connection between the first guide mechanism 32 and the second guide mechanism 41, thereby automatically separating the shielded container 3 and other components to facilitate the recovery of the target assembly 2 (especially the target material 21). Notably, the position of the target assembly 2 in Figure 5 is closer to the release device 6 than the position in Figure 4.

[0096] Generally, the preset position can be located at the first guide mechanism 32. That is, after part or all of the target component 2 has been transferred to the first guide mechanism 32, the first guide mechanism 32 and the second guide mechanism 41 are unlocked and released when the target component 2 reaches the preset position. Of course, under the condition that the design allows, the preset position can also be located on the second guide mechanism 41, as long as the target component 2 can smoothly cooperate with the first guide mechanism 32 and slide along the first guide mechanism 32 after passing through the preset position so that the first guide mechanism 32 and the second guide mechanism 41 are unlocked and released. In an optional embodiment, as shown in Figures 6, 7 and 8, the releasable device 6 includes a latching part 61 and a moving part 62. The moving part 62 can move relative to the latching part 61, so that the moving part 62 can connect or disengage from the latching part 61. After the moving part 62 disengages from the latching part 61, the first guide mechanism 32 and the second guide mechanism 41 are unlocked and released, that is, the connection between the first guide mechanism 32 and the second guide mechanism 41 is broken. The latching part 61 is disposed on the second guide mechanism 41, and the moving part 62 is disposed on the first guide mechanism 32.

[0097] As shown in Figures 6 and 7, the target assembly 2 includes a contact portion 24 located at the second end of the bracket 22. When the target assembly 2 moves to a preset position, the contact portion 24 of the target assembly 2 can abut against the moving portion 62, thereby driving the moving portion 62 to move relative to the locking portion 61 to disconnect the connection between the first guide mechanism 32 and the second guide mechanism 41. In this embodiment, the moving portion 62 can rotate relative to the locking portion 61. As shown in Figures 6, 7, and 8, specifically, the locking portion 61 includes a locking groove 611, and the moving portion 62 includes a locking pin 621. When in the connected state, the locking pin 621 is inserted into the locking groove 611. When the locking pin 621 moves relative to the locking portion 61, the locking pin 621 can rotate away from the locking groove 611. Specifically, the moving part 62 also includes a contact part 622. After the contact part 24 of the target assembly 2 comes into contact with the contact part 622, the target assembly 2 still has a tendency to move downward or partially downward. The contact part 622 rotates clockwise under the drive of the target assembly 2. At the same time, the locking pin 621 also rotates clockwise and disengages from the locking groove 611.

[0098] Of course, in other alternative embodiments, the moving part 62 may also move relative to the locking part 61. Alternatively, the moving part 62 may also have relative motion such as movement and rotation relative to the locking part 61.

[0099] In another alternative embodiment, the latching part 61 may also be provided on the first guide mechanism 32, and correspondingly, the moving part 62 may also be provided on the second guide mechanism 41. Specifically, the structure and shape of the latching part 61 and the moving part 62 can be referred to the above description, and will not be repeated here.

[0100] In an optional embodiment, the releaseable device 6 further includes a position sensing mechanism. When the target assembly 2 moves to a preset position, the position sensing mechanism can trigger the movement of the moving part 62, thereby disengaging the first guide mechanism 32 and the second guide mechanism 41. Generally, the position sensing mechanism can be a sensor, contact switch, or other sensing component with detection and signal transmission functions.

[0101] In an optional embodiment, the releaseable device 6 further includes a transmission component 63. Referring to Figures 19 and 20, after the target assembly 2 reaches a preset position, the transmission component 63 drives the moving part 62 to move, causing the moving part 62 to disengage from the latching part 61. The transmission component drives a rod 631, one end of which is connected to the moving part 62, and the other end of which is connected to a cylinder or other power source. The drive rod 631 drives the moving part 62 to move, causing the moving part 62 to disengage from the latching part 61. In some embodiments, a limit switch or photoelectric sensor is set at the preset position. After detecting that the target assembly 2 has reached the preset position, the target assembly contacts the limit switch at the preset position, thereby generating a control signal that causes the cylinder to move, driving the moving part 62. Alternatively, the target assembly at the preset position activates the photoelectric switch, thereby generating a control signal that causes the cylinder to move, driving the moving part 62 to move. Thus, the moving part 62 disengages from the latching part 61, and the releaseable device 6 is unlocked. The target component can be positioned at the first guide mechanism 32. That is, after some or all of the target component 2 has been transferred to the first guide mechanism 32, the first guide mechanism 32 and the second guide mechanism 41 unlock and release when the target component 2 reaches the preset position. Of course, if the design allows, the preset position can also be located on the second guide mechanism 41, as long as the target component 2 can smoothly cooperate with the first guide mechanism 32 and slide along the first guide mechanism 32 after passing through the preset position and unlocking and releasing between the first guide mechanism 32 and the second guide mechanism 41.

[0102] In this embodiment, as shown in FIG9, the second guiding mechanism 41 may include a first guiding portion 411 and a second guiding portion 412. The extending direction of the first guiding portion 411 is parallel or substantially parallel to the transmission direction of the charged particle beam. The second guiding portion 412 has opposing first and second ends. The first end of the second guiding portion 412 is pivotally connected to the first guiding portion 411. The second end of the second guiding portion 412 is detachably connected to the first guiding mechanism 32. When the second end of the second guiding portion 412 is disconnected from the first guiding mechanism 32 via the releasable device 6, the second guiding portion 412 can rotate relative to the first guiding portion 411, thereby separating the first guiding mechanism 32 and the second guiding mechanism 41.

[0103] In this embodiment, at least a portion of the second guide mechanism 41 extends in a direction different from that of the first guide mechanism 32. The first guide portion 411 of the second guide mechanism 41 can extend horizontally, while the first guide mechanism 32 extends against the inner wall of the shielded container 3, or extends at a certain angle to the inner wall of the shielded container 3, or extends vertically. To guide the target assembly 2 from the first guide portion 411 to the first guide mechanism 32, at least a portion of the second guide portion 412 can be arc-shaped or linear, extending in a direction generally consistent with the direction of the first guide portion 411 toward the first guide mechanism 32. In this specification, examples of this structure of the first guide mechanism 32 and the second guide mechanism 41 will be used for illustration. Of course, in other optional embodiments, the arrangement of the first guide mechanism 32 and the second guide mechanism 41 can also be set according to actual needs. For example, at least a portion of the second guide portion 412 can be set to extend downward in a direction generally consistent with the direction of the first guide portion 411 toward the first guide mechanism 32. Or, for example, the first guide mechanism 32 extends upward in a generally vertical direction. At least a portion of the second guide portion 412 may be in the form of an arc or line extending upward from the first guide portion 411 toward the first guide mechanism 32.

[0104] Preferably, a first angle is formed between the line connecting the two ends of the second guide portion 412 projected in the horizontal plane and the line connecting the two ends of the first guide portion 411 projected in the horizontal plane, and a second angle is formed between the line connecting the two ends of the second guide portion 412 projected in the vertical plane and the line connecting the two ends of the first guide portion 411 projected in the vertical plane, and both the first angle and the second angle are not less than 90 degrees.

[0105] As shown in Figures 10 and 11, the shielded container 3 may further include a cover assembly 33, which is movable relative to the housing 31 (e.g., rotating, pivoting, or moving), thereby enabling the housing 31 to be opened or closed. When the housing 31 is in the closed state, the cover assembly 33 and the housing 31 can enclose and form an accommodating space.

[0106] Before the target assembly 2 enters the housing 31, the housing 31 is in the open state. After the target assembly 2 is fully inside the housing 31, the cover assembly 33 can move relative to the housing 31 (e.g., move, rotate, or pivot), causing the housing 31 to switch from the open state to the closed state. This allows the target assembly 2 to be placed within a sealed, shielded container 3, thereby reducing the leakage of radioactive material from the target assembly 2.

[0107] In an optional embodiment, the housing 31 has an inner cavity 311, and the first guide mechanism 32 is movable relative to the housing 31 (e.g., moved or rotated). When the first guide mechanism 32 and the second guide mechanism 41 are connected, a portion of the first guide mechanism 32 is located outside the housing 31. After the first guide mechanism 32 and the second guide mechanism 41 are disconnected, the first guide mechanism 32 can move relative to the housing 31, allowing all or part of its previously exposed portion to enter the housing 31. At this time, the cover assembly 33, after closing, can accommodate both the target assembly 2 and the first guide mechanism 32 within the housing 31. In other words, in this embodiment, the accommodating space is equal to or substantially equal to the inner cavity 311 of the housing 31. This arrangement of the accommodating space being equal to or substantially equal to the inner cavity of the housing 31 ensures that after the releaseable device 6 is unlocked, the second guide portion 412 can pivot smoothly relative to the first guide portion 411 without being interfered with by the housing 31.

[0108] In one optional embodiment, a guiding mechanism may be provided between the first guiding mechanism 32 and the second guiding mechanism 41 (second guiding portion 412). The guiding mechanism includes a guide groove (not shown in the figure) and a guide post 101 that can pass through the guide groove. Referring to Figure 8, in this embodiment, the guide post 101 protrudes from the first guiding mechanism 32. The guide groove is provided on the second guiding mechanism 41. During the disengagement and connection of the first guiding mechanism 32 and the second guiding mechanism 41, the guide post 101 and the guide groove can facilitate limiting and guiding the disengagement and connection of the first guiding mechanism 32 and the second guiding mechanism 41. In other optional embodiments, the guide post 101 may also be provided on the second guiding mechanism 41, and correspondingly, the guide groove may also be provided on the first guiding mechanism 32. Furthermore, the guiding mechanism may also be other corresponding structures or devices with guiding functions.

[0109] To some extent, the guide post 101 may interfere with the disengagement of the first guide mechanism 32 and the second guide mechanism 41. After the releasable device 6 is opened, the guide post 101 is housed in the guide groove before the first guide mechanism 32 retracts. With the guide post 101 in place, the first guide mechanism 32 and the second guide mechanism 41 can only disengage after the first guide mechanism 32 retracts. Therefore, the working process in this embodiment can be as follows: Referring to FIG7, after the target assembly 2 moves to the preset position, the target assembly 2 can abut against the moving part 62, thereby driving the moving part 62 to move, and thus unlocking the releasable device 6. Referring to FIG8, when the target assembly 2 continues to move to the predetermined position of the first guide mechanism 32, the first guide mechanism 32 retracts, thereby causing the guide post 101 to disengage from the guide groove. At this time, referring to FIG9, the second guide part 412 can pivot relative to the first guide part 411.

[0110] In this embodiment, the predetermined position can be the termination position of the target component 2 within the housing 31, that is, after the target component 2 ceases to move relative to the housing 31, the first guide mechanism 32 begins to move relative to the housing 31. Of course, in other optional embodiments, the predetermined position can be any position between the termination position of the target component 2 within the housing 31 and the preset position. That is, in this embodiment, the target component 2 and the first guide mechanism 32 move simultaneously.

[0111] In an optional embodiment, the target component can be positioned at the first guide mechanism 32. Further, the preset position is any position between the target component 2's termination position and the termination position within the housing 31, after some or all of the target component 2 has been transferred to the first guide mechanism 32. When the target component 2 reaches this preset position, the first guide mechanism 32 and the second guide mechanism 41 are unlocked. At the position where the target component is located when the release device is unlocked, the first guide mechanism 32 can also be configured to move relative to the housing 31, thereby causing the guide post 101 to disengage from the second guide mechanism 41. That is, in this embodiment, the preset position where the target component 2 is unlocked by the release device 6 coincides with the predetermined position where the target component 2 is retracted by the first guide mechanism 32. At this position, the unlocking of the release device 6 and the retraction of the first guide mechanism 32 occur simultaneously. At this time, the predetermined position only needs to be different from the termination position of the target component 2 within the housing 31, so as to leave room for the first guide mechanism 32 to cause the guide post 101 to disengage from the second guide mechanism 41 and retract. In this embodiment, the predetermined position coincides with the releaseable device. Referring to Figures 19 and 20, after the target assembly 2 moves to this coincident position, a limit switch or photoelectric sensor is set at this position. After detecting that the target assembly 2 has moved to the preset position, the target assembly contacts the limit switch at the preset position, thereby generating a control signal. Alternatively, the target assembly at the preset position activates the photoelectric switch, thereby generating a control signal. This invention does not limit the specific actions taken in this regard. The control signal causes the cylinder to move, driving the drive rod 631 to move, which in turn drives the moving part 62 to move. As a result, the moving part 62 disengages from the latching part 61, thereby unlocking the releaseable device 6. The control signal, through the cylinder or the like, also causes the first guide mechanism 32 to retract under the action of the cylinder, thereby causing the guide post 101 to disengage from the guide groove, and thus causing the first guide mechanism 32 to disengage from the second guide mechanism 41. At this time, the second guide part 412 can pivot relative to the first guide part 411.

[0112] In another alternative embodiment, the housing 31 has an inner cavity 311, and a first guide mechanism 32 is fixedly mounted on the housing 31. After the first guide mechanism 32 is separated from the second guide mechanism 41, the first guide mechanism 32 can be accommodated in the accommodating space formed by the cover assembly 33 and the housing 31. In other words, in this embodiment, the accommodating space is larger than the inner cavity 311 of the housing 31. This arrangement also ensures that after the releaseable device 6 is unlocked, the second guide mechanism 41 can pivot smoothly without being interfered with by the side wall of the housing 31.

[0113] Furthermore, during the movement of the target assembly 2 along the second guide mechanism 41, the second end of the bracket 22 is always closer to the shielded container 3 than the first end of the bracket 22; the second end of the bracket 22 enters the shielded container 3 before the first end of the bracket 22. Specifically, the target assembly 2 also includes a power unit (not shown in the figure) for driving the movement of the bracket 22. The power unit can be located at the second end of the bracket 22, thereby maximizing the distance between the power unit and the target material 21, and thus minimizing the impact of the target material 21's radioactivity on the power unit.

[0114] Specifically, the surface of the second guide mechanism 41 supporting the bracket 22 is set as a guide surface. The guide surface extends continuously along the second guide mechanism 41, and the extension direction of the guide surface is consistent with the extension direction of the second guide mechanism 41. During the movement along the second guide mechanism 41, the target material 21 is always located on the same side of the guide surface.

[0115] Referring to Figure 5, this application embodiment also discloses an automatic target changing system. The automatic target changing system includes a shielded container 3, which includes a housing 31 and a first guide mechanism 32 disposed on the housing 31; a second guide mechanism 41, which and the first guide mechanism 32 are configured to guide the movement of the target assembly 2; and a release device 6, which connects the first guide mechanism 32 to the second guide mechanism 41. When the target assembly 2 moves to a preset position, the release device 6 is configured to disconnect the connection between the first guide mechanism 32 and the second guide mechanism 41.

[0116] As mentioned above, when the target assembly 2 moves to the preset position by the first guide mechanism 32 and the second guide mechanism 41, the release device 6 can separate the first guide mechanism 32 and the second guide mechanism 41, thereby automatically separating the shielded container 3 from other components. The specific structures of the shielded container 3, the second guide mechanism 41, the first guide mechanism 32, and the release device 6 in the automatic target changing system can be referred to the above description and will not be repeated here.

[0117] Referring to Figures 5 and 8, this application also discloses a neutron capture therapy system, which may include a target assembly 2, a shielded container 3, a first guiding mechanism 32, etc. Typically, if the first guiding mechanism 32 and the second guiding mechanism 41 extend in the same direction, the structure of the shielded container is more complex and the site layout is more difficult. To simplify the structural design, the first guiding mechanism 32 and at least part of the second guiding mechanism 41 extend in different directions. For example, the first guide portion 411 of the aforementioned second guiding mechanism 41 may extend horizontally. The first guiding mechanism 32 extends vertically downwards. To guide the target assembly 2 from the first guide portion 411 to the first guiding mechanism 32, at least part or all of the second guide portion 412 may be arc-shaped or linear, extending downwards from the first guide portion 411 to the first guiding mechanism 32. In this specification, examples of this structure of the first guiding mechanism 32 and the second guiding mechanism 41 will be used throughout the description. Of course, in other optional embodiments, the arrangement of the first guiding mechanism 32 and the second guiding mechanism 41 can also be set according to actual needs. For example, at least a portion of the second guide portion 412 may tend to extend downward from the first guide portion 411 toward the first guide mechanism 32. Alternatively, the first guide mechanism 32 may extend upward in a vertical direction. At least a portion of the second guide portion 412 may be arc-shaped or linear, extending upward from the first guide portion 411 toward the first guide mechanism 32.

[0118] Regardless, if the extension direction of at least part of the second guide mechanism 41 is not consistent with the extension direction of the first guide mechanism 32, the target assembly 2 will change its direction of movement during the guiding process. Considering the significant weight of the target assembly 2, this change in direction may, on the one hand, cause the target assembly 2 to exert an impact force on the first guide mechanism 32, the second guide mechanism 41, or other components. Inevitably, such impact forces may affect the service life and accuracy of the components. On the other hand, if the speed of the target assembly 2 exceeds the permissible range during the change of direction, it may detach from the guide device 4, potentially causing a serious accident. Especially if the speed of the target assembly 2 may further increase due to its own weight, both the impact force and speed could pose even greater risks.

[0119] Referring to Figures 10, 11, 12, and 13, the neutron capture system in this embodiment may further include a first buffer device 8. During the movement of the target assembly 2 along the second guide mechanism 41 towards the first guide mechanism 32, the first buffer device 8 provides a buffering force to the target assembly 2. In one embodiment of the invention, Figure 12 shows the target assembly 2 positioned on the second guide mechanism 41, and at this point, the first buffer device 8 has not yet come into contact with the target assembly 2. Referring to Figure 13, as the target assembly 2 continues to move along the second guide mechanism 41 towards the first guide mechanism 32, the first buffer device 8 provides a buffering force to the target assembly 2. The buffering force provided by the first buffer device 8 to the target assembly 2 buffers the movement of the target assembly 2, for example, through contact or electromagnetic force. Obviously, during the change of movement direction of target component 2, the buffering force can limit the movement speed of target component 2 within an allowable range, ensuring that during the transition from a moving state to a stationary state within the shielded container 3, target component 2 is protected from impact due to changes in movement direction and / or speed; simultaneously, the impact force generated by target component 2 on guide device 4 is controlled within an allowable range, and target component 2 will not detach from guide device 4 due to excessive speed. Generally, the first buffering device 8 can cause target component 2 to be in a state of variable speed or deceleration. Of course, under permissible conditions, the first buffering device 8 can also cause target component 2 to be in a state of acceleration or slight acceleration, as long as the movement speed of target component 2 is limited within an allowable range.

[0120] In this embodiment, during the change of movement direction of the target component 2, the first buffer device 8 can provide a buffering force to the target component 2 throughout the entire process. Obviously, this method can effectively buffer the target component 2, so that the entire movement process of the target component 2 is controlled.

[0121] Of course, where permissible, during the change of direction of movement of target assembly 2, the first buffer device 8 may only provide a buffering force to target assembly 2 for a short distance. For example, during the initial period when target assembly 2 changes its direction of movement, the first buffer device 8 may not provide a buffering force to target assembly 2. When target assembly 2 reaches a certain position, the first buffer device 8 may begin to provide a buffering force. Alternatively, after the first buffer device 8 provides a buffering force to target assembly 2 for a certain distance, the first buffer device 8 may disengage from target assembly 2. Although target assembly 2 loses its buffering force at this point, its running speed and the subsequent impact on the target material and the track caused by deceleration to a stop are controlled within permissible limits. For example, during the process of the target component 2 changing its direction of motion, the first buffer device 8 can provide a buffering force to the target component 2 for a certain distance (or time). After that, the first buffer device 8 temporarily stops providing a buffering force to the target component 2. Then, after the first buffer device 8 has moved for a certain distance or time, the first buffer device 8 continues to provide a buffering force to the target component 2 for a certain distance (or time).

[0122] In an optional embodiment, the first buffer device 8 includes a power cylinder disposed on the housing 31. The power cylinder includes a cylinder body (not shown) and a power mechanism 82. The power mechanism 82 passes through the cylinder body and is movable relative to the cylinder body. The power transmission medium inside the cylinder body can be liquid or gas. Considering space saving and the large weight of the target assembly 2, the cylinder body is generally fixedly disposed at the bottom of the housing 31. However, where permissible, the cylinder body of the first buffer device 8 can also be fixedly disposed on, for example, the inner wall of the housing 31. The free end of the power mechanism 82 can be provided with a support portion 86 that abuts against the target assembly 2. The support portion 86 can be made of a flexible material such as rubber to avoid damage to the target assembly 2 during the buffer contact process.

[0123] In one embodiment of the present invention, referring to FIG13, when the target assembly 2 moves to a certain buffer position on the second guide mechanism 41, the free end of the power mechanism 82 can abut against the target assembly 2, thereby providing a buffering force to the target assembly 2. During the process of the target assembly 2 moving from the second guide mechanism 41 to the first guide mechanism 32, there is displacement not only in the vertical direction but also in the horizontal direction. During the process of the target assembly 2 entering the shielded container 3 along the second guide mechanism 41 and the first guide mechanism 32, a portion of the structure of the target assembly 2 is configured to have an overlapping motion trajectory that interferes with the first buffer device 8 as the target assembly 2 moves, so that the first buffer device 8 abuts against the target assembly 2. Therefore, in space, because the target assembly 2 has a partially overlapping motion trajectory with the first buffer device 8, the first buffer device 8 will dynamically contact and interfere with the partially overlapping structure of the target assembly 2 moving along the second guide mechanism 41 and the first guide mechanism 32. Due to the overlapping motion trajectories, the first buffer device 8 and the target assembly 2 interfere with each other at the points of overlap, thus generating an interaction force between them. The force exerted by the first buffer device 8 on the target assembly 2 will have a buffering effect on it; this force is the buffering force provided by the first buffer device 8 in contact with the target assembly 2. Although the power mechanism 82 of the first buffer device 8 is always in contact with the target assembly 2, the contact position between the first buffer device 8 and the target assembly 2 changes as the target assembly 2 moves horizontally. Referring to Figure 11, considering that the target assembly 2 is heavy and the first buffer device 8 is subjected to a large force, the inner side wall of the housing 31 can also be provided with a limiting track 36 to limit the movement of the first buffer device 8. This can ensure the movement trajectory of the first buffer device 8 and also ensure the rigidity of the first buffer device 8.

[0124] Furthermore, referring to Figure 13, in one embodiment of the present invention, the target assembly 2 has a buffer braking part 23, the buffer braking part 23 has a buffer braking surface 231, and the buffer braking surface 231 is provided with at least two buffer braking positions. Specifically, the buffer braking part 23 is close to the second end of the bracket 22. In this embodiment, the two buffer braking positions are the first buffer braking position 2311 and the second buffer braking position 2312. During the process of the target assembly 2 entering the shielded container 3 along the second guide mechanism 41 and the first guide mechanism 32, the first buffer device 8 sequentially abuts against the first buffer braking position 2311 and the second buffer braking position 2312, that is: the target assembly 2 and the first buffer device 8 sequentially abut against the first buffer braking position 2311 and the second buffer braking position 2312 form partially or completely mutually interfering overlapping motion trajectories. In this embodiment of the present invention, the mutually interfering overlapping motion trajectory also includes the position located between the first buffer braking position 2311 and the second buffer braking position 2312, at which part of the structure of the target assembly 2 sequentially abuts against the first buffer device 8. In this embodiment, during the operation of the first buffer device 8, the power mechanism 82 is always in contact with the buffer braking surface 231 through the support part 86, and the contact position between the power mechanism 82 and the target assembly 2 is always restricted on the buffer braking surface 231. As a result, the movement of the target assembly 2 relative to the power mechanism 82 is more stable.

[0125] In one embodiment, the first buffer device 8 can provide a buffering force not only to the target assembly 2 during its movement along the second guide mechanism 41 to the first guide mechanism 32, but also to the target assembly 2 when it is on the first guide mechanism 32. For example, from the initial contact to the target assembly 2 reaching the final position (resting position), the power mechanism 82 of the first buffer device 8 is always in contact with the target assembly 2.

[0126] Referring to Figure 11, in another optional embodiment, to provide cushioning for the target assembly 2 during its descent, the power mechanism 82 needs to have a large stroke. Therefore, the moving distance of the power mechanism 82 of the first buffer device 8 in the previous embodiment is relatively long. The shielded container 3 may also include a second buffer device 9. During the movement of the target assembly 2 along the first guide mechanism 32, the second buffer device 9 can provide a cushioning force to the target assembly 2. Referring to Figure 11, after the first buffer device 8 provides a certain cushioning distance (and / or, cushioning time) to the target assembly 2, the second buffer device 9 can provide a cushioning force to the target assembly 2. In other words, the cushioning range of the first buffer device 8 in the extension direction (first direction Y) of the first guide mechanism 32 does not completely coincide with the cushioning range of the second buffer device 9 in the first direction Y. Generally, in order to keep the target assembly 2 in a cushioned state, the second buffer device 9 can generate a cushioning force to the target assembly 2 before the first buffer device 8 and the target assembly 2 separate. In other words, during a certain period of operation of the target assembly 2, the first buffer device 8 and the second buffer device 9 can simultaneously provide buffering force to the target assembly 2. Of course, if the speed of the target assembly 2 allows, for example, less than 1 m / s, or if the target assembly 2 cooperates with the second buffer device 9 and is subjected to a small impact force from the second buffer device 9, or under other permissible circumstances, the first buffer device 8 can detach from the target assembly 2 before the second buffer device 9 generates a buffering force on the target assembly 2.

[0127] In this embodiment, the second buffer device 9 may include a power cylinder such as the first buffer device 8 in the previous embodiment; the specific structure of the second buffer device 9 will not be described in detail here. Of course, in other optional embodiments, the second buffer device 9 may also be other mechanisms that can provide buffering for the target assembly 2.

[0128] In an optional embodiment, the second buffer device 9 is disposed inside the shielded container, and the target assembly 2 is positioned at the preset position when it moves along the first guide mechanism 32 to a position that contacts the second buffer device 9. At this preset position, the release device 6 is unlocked via the transmission structure 63.

[0129] In an optional embodiment, as shown in FIG11, after the target component 2 contacts the second buffer device 9, the second buffer device 9 buffers the target component 2. The position where the target component reaches the second buffer device 9 and just makes contact with the second buffer device 9 is defined as the preset position and the predetermined position. The second buffer device 9 is provided with a support plate. At the position where the target component reaches the support plate of the second buffer device 9 and makes contact with the second buffer device 9, the preset position and the predetermined position coincide. That is, at the coincident position, the release device 6 unlocks and the first guide mechanism 32 retracts simultaneously. After the target component 2 runs to the coincident position, a limit switch is set on the surface of the second buffer device 9 that contacts the target component 2, such as any position where the support plate contacts the target component 2, or a photoelectric sensor is set on the surface of the second buffer device 9 that contacts the target component 2 and other positions related to the position of the second buffer device 9. As long as the target component 2 can affect the photoelectric sensor after reaching the position of contact with the second buffer device 9, the present invention does not limit the position of the photoelectric sensor. After the target assembly 2 moves to the preset position or predetermined position, the target assembly 2 contacts the limit switch at the preset position, thereby generating a control signal, or the target assembly 2 causes the photoelectric switch to operate at the preset position, thereby generating a control signal; the present invention does not limit this. The control signal causes the cylinder to move, driving the drive rod 631 to move, thereby driving the moving part 62 to move. As a result, the moving part 62 disengages from the latching part 61, thereby unlocking the release device 6. The control signal, through the cylinder, also causes the first guide mechanism 32 to retract under the drive of the cylinder, thereby causing the guide post 101 to disengage from the guide groove, and thus causing the first guide mechanism 32 to disengage from the second guide mechanism 41. At this time, the second guide part 412 can pivot relative to the first guide part 411.

[0130] In this embodiment, the first guide mechanism 32 extends along a first direction Y (e.g., a vertical direction) and has two opposite sides along a second direction Z, wherein the second direction Z is substantially perpendicular to the first direction Y. A first buffer device 8 is disposed on one side of the first guide mechanism 32. The first buffer device 8 includes a first motion unit 83 and a second motion unit 84. The first motion unit 83 is disposed on the housing 31 and is movable relative to the housing 31; the second motion unit 84 is disposed on the first motion unit 83 and is movable relative to the first motion unit 83, and the second motion unit 84 can contact or disengage from the target assembly 2.

[0131] In this embodiment, both the first motion unit 83 and the second motion unit 84 may include a power cylinder (e.g., a hydraulic cylinder, a pneumatic cylinder, etc.). The first motion unit 83 can move along the extension direction of the first guide mechanism 32, and the second motion unit 84 can move along the extension direction away from the first guide mechanism 32 (e.g., the second direction Z). Referring to Figures 14 and 15, the shielded container 3 also includes a biasing track 37 disposed on the housing 31. In Figure 14, the first buffer device 8 has been disengaged from the target assembly 2. As shown in Figure 14, the biasing track 37 gradually tilts from top to bottom in a direction away from the first guide mechanism 32. During the process of the first motion unit 83 gradually moving downward under the guidance of the first guide mechanism 32, the second motion unit 84, under the action of the biasing track 37, gradually moves along the biasing track 37 in a direction away from the first guide mechanism 32 (the second direction Z), thereby disengaging from the target assembly 2.

[0132] In this embodiment, the second motion unit 84 and the first motion unit 83 can operate simultaneously. That is, while the first motion unit 83 moves simultaneously with the target assembly 2 along the extension direction of the first guide mechanism 32, the second motion unit 84 moves towards the outer edge of the first side of the target assembly 2. In another optional embodiment, the second motion unit 84 can operate again after the first motion unit 83 comes to a stop. That is, while the first motion unit 83 moves simultaneously with the target assembly 2 along the extension direction of the first guide mechanism 32, the second motion unit 84 is stationary. When the first motion unit 83 comes to a stop, the second motion unit 84 starts to move again. For example, the second motion unit 84 can start to move after the first motion unit 83 has moved a certain distance or time along with the target assembly 2. In other words, the difference from the above embodiment is that the first motion unit 83 and the second motion unit 84 have a period of time during which they operate simultaneously.

[0133] In another alternative embodiment, the second motion unit 84 can move along the extension direction (first direction Y) of the first guide mechanism 32, and the first motion unit 83 can move in a direction away from the extension direction of the first guide mechanism 32 (e.g., second direction Z).

[0134] Of course, in other alternative embodiments, the first motion unit 83 and the second motion unit 84 can also be designed as linkage mechanisms, cam mechanisms, rack and pinion structures, etc., as needed. In addition, the motion of the first motion unit 83 and the second motion unit 84 is not limited to linear motion. Where the design allows, the motion of the first motion unit 83 and the second motion unit 84 can also adopt rotation or other motion methods.

[0135] In a preferred embodiment, referring to Figures 10 and 11, the shielded container 3 further includes a drive unit 34 and an opening / closing unit 35. The opening / closing unit 35 controls the opening and closing of the cover assembly 33, and the drive unit 34 can simultaneously drive the first buffer device 8 and the opening / closing unit 35 to move. For example, the drive unit 34 can be connected to a power mechanism 82, thereby moving with the power mechanism 82. The opening / closing unit 35 may include a connecting rod, with its two ends pivotally connected to the drive unit 34 and the cover assembly 33, respectively. During the movement of the first buffer device 8 along the first guide mechanism 32 with the target assembly 2, the drive unit 34 can drive the opening / closing unit 35 to move, causing the cover assembly 33 to switch from an open state to a closed state, or from a closed state to an open state. Obviously, this structure has high working efficiency and can reduce the time that the target material 21 of the target assembly 2 is exposed in the first space R1. In another optional embodiment, the drive unit 34 can simultaneously drive the second buffer device 9 and the opening / closing unit 35 to move.

[0136] In an alternative embodiment, referring to Figures 4 and 16, unlike the embodiments described above, the first buffer device 8 includes a support rod 85, which has a first end close to the target assembly 2 and a second end away from the target assembly 2. The support rod 85 has a preset rotation center 851 located between its first end and second end. The first end of the support rod 85 includes a support portion 86 that abuts against the target assembly 2, and the second end of the support rod 85 is connected to a power source 81. Referring to Figure 17, when the target assembly 2 and the first end of the support rod 85 are in contact, the first end of the support rod 85 is subjected to pressure from the target assembly 2. This pressure causes the first end of the support rod 85 to tend to move downward. The second end of the support rod 85 is subjected to a pulling force from the power source 81. This pulling force also causes the second end of the support rod 85 to tend to move downward. Since the support rod 85 can pivot around the preset rotation center 851 between the first end and the second end, the drive control of the second end of the support rod 85 by the power source 81 achieves the purpose of controlling the speed at which the first end of the support rod 85 is dragged by the target assembly 2 to follow the movement of the target assembly 2, thereby achieving the purpose of providing a buffering force to the target assembly 2. Understandably, as the first end of the support rod 85 moves toward the first guide mechanism 32 along with the target assembly 2, the support rod 85 rotates in the rotation direction X around a preset rotation center 851. The second end of the support rod 85 also rotates accordingly. Simultaneously, the power source 81 can provide constraint to the second end of the support rod 85, limiting its rotation in the rotation direction X, thereby allowing the supporting portion 86 of the support rod 85 to provide a buffering force to the target assembly 2. Preferably, the supporting portion 86 of the support rod 85 can be made of a flexible material such as rubber to prevent damage to the target assembly 2 during contact.

[0137] Specifically, the housing 31 is provided with a rod 102 extending vertically or substantially vertically. One end of the rod 102 is higher than the housing 31, and the preset rotation center 851 formed between the support rod 85 and the rod 102 is higher than the housing 31. The power source 81 can generally be a hydraulic cylinder, pneumatic cylinder, linkage mechanism, cam mechanism, rack and pinion structure, etc. When the target assembly 2 and the first end of the support rod 85 are not in contact, the first end of the support rod 85 is higher than the preset rotation center 851, and the preset rotation center 851 is higher than the second end of the support rod 85. After the target assembly 2 and the support portion 86 of the support rod 85 come into contact and move a certain distance, the support portion 86 of the support rod 85 is lower than the preset rotation center 851 and also lower than the second end of the support rod 85, until the support portion 86 of the support rod 85 separates from the target assembly 2.

[0138] In a preferred embodiment, the preset rotation center 851 is floatingly set by an adaptive mechanism (not shown), thereby making the support 86 adaptive to the target assembly 2. For example, the adaptive mechanism may include an elastic element disposed between the preset rotation center 851 of the support rod 85 and the rod body 102. Under the interaction of the target assembly 2 and the power source 81, the elastic element, i.e., the adaptive mechanism, can adaptively adjust the position of the preset rotation center 851 of the support rod 85.

[0139] Similar to the aforementioned embodiments, referring to FIG18, the target assembly 2 has a buffer braking part 23, which has a buffer braking surface 231, and the buffer braking surface 231 is provided with at least two buffer braking positions. Specifically, the buffer braking part 23 is located near the second end of the bracket 22. In this embodiment, the two buffer braking positions are a first buffer braking position 2311 and a second buffer braking position 2312. During the process of the target assembly 2 entering the shielded container 3 along the second guide mechanism 41 and the first guide mechanism 32, the first buffer device 8 sequentially abuts against the first buffer braking position 2311 and the second buffer braking position 2312, and the first buffer braking position 2311 and the second buffer braking position 2312 that the target assembly 2 and the first buffer device 8 sequentially abut against each other form partially or completely overlapping motion trajectories that interfere with each other. In this embodiment of the invention, the overlapping motion trajectory that interferes with each other also includes the position between the first buffer braking position 2311 and the second buffer braking position 2312 where the target assembly 2 and the first buffer device 8 sequentially abut against each other. Referring to Figure 18, in order to separate the support portion 86 from the target assembly 2, the target assembly 2 has a notch 232, through which the support portion 86 can detach from the target assembly 2. In other words, the first buffer device 8 can sequentially abut against each of the buffer braking positions of the buffer braking surface 231. After contacting the last buffer braking position, i.e., the second buffer braking position 2312, the first buffer device 8 has completed sequential contact with each of at least two buffer braking positions, and the support portion 86 can enter the notch 232, thereby separating from the target assembly 2. Specifically, the buffer braking positions are not limited to two. In a preferred embodiment, during the process from contact between the support portion 86 and the target assembly 2 to separation, the contact area between the buffer braking surface 231 of the target assembly 2 and the support portion 86 gradually decreases. This allows the target assembly 2 and the support portion 86 to separate more smoothly.

[0140] As in the aforementioned embodiments, continuing to refer to Figure 4, the shielded container 3 may further include a second buffer device 9. After the first buffer device 8 is separated from the target assembly 2, the second buffer device 9 can provide a buffering force to the target assembly 2. The specific structure of the second buffer device 9 is as described above and will not be repeated here.

[0141] In an optional embodiment, both the first buffer device 8 and the second buffer device 9 can provide a buffering force to the target assembly 2 by means of electromagnetic force, thereby reducing the impact of the target assembly 2 on the first guide mechanism 32 and the second guide mechanism 41, and also keeping the speed of the target assembly 2 within an allowable range.

[0142] Referring to Figures 4 and 12, another aspect of this application discloses an automatic target-changing system, comprising:

[0143] The shielded container 3 includes a housing 31 and a first guide mechanism 32 disposed on the housing 31;

[0144] The second guide mechanism 41 and the first guide mechanism 32 are configured to guide the movement of the target assembly 2, and at least part of the extension direction of the second guide mechanism 41 is not consistent with the extension direction of the first guide mechanism 32.

[0145] The first buffer device 8 provides a buffering force to the target assembly 2 as the target assembly 2 moves along the second guide mechanism 41 to the first guide mechanism 32.

[0146] As previously described, during the movement of the target assembly 2 along the second guide mechanism 41 to the first guide mechanism 32, the first buffer device 8 can provide a buffering force to the target assembly 2, thereby reducing the impact force of the target assembly 2 on the first guide mechanism 32 and / or the second guide mechanism 41, and also reducing the risk of the target assembly 2 detaching from the first guide mechanism 32 and / or the second guide mechanism 41. The specific structures of the shielded container 3, the second guide mechanism 41, and the first buffer device 8 in the automatic target changing system can be referred to the above description and will not be repeated here.

[0147] Referring to Figure 11, in one embodiment of the present invention, the first guiding mechanism 32 extends along the first direction Y, and the buffering range of the first buffer device 8 in the first direction Y does not completely overlap with the buffering range of the second buffer device 9 in the first direction Y. If only the first buffer device 8 is provided, since it needs to provide buffering for the target assembly 2 over a long buffering stroke, the first buffer device 8 will require a large arrangement space along the buffering direction. This situation places large requirements on the size of the shielding container 3 and imposes high requirements on the design dimensions of the shielding container 3. If a large shielding container 3 is provided solely due to the spatial layout requirements of the first buffer device 8, it will result in material waste and ineffective utilization of the space of the shielding container 3. If the second buffer device 9 is provided, after the first buffer device 8 and the target assembly 2 are separated, the second buffer device 9 can continuously provide buffering for the target assembly 2, reducing the space occupied by the first buffer device 8 to complete the buffering stroke, thereby keeping the size of the housing 31 within a smaller range.

[0148] It should be understood that the above description is for illustrative purposes and not for limitation. Many embodiments and applications beyond the provided examples will be apparent to those skilled in the art upon reading the above description. Therefore, the scope of this teaching should not be determined by reference to the above description, but rather by reference to the foregoing claims and the full scope of their equivalents. For purposes of completeness, all articles and references, including patent applications and publications, are incorporated herein by reference. The omission of any aspect of the subject matter disclosed herein in the foregoing claims is not intended as a waiver of that subject matter, nor should it be construed as an indication that the applicant has not considered that subject matter as part of the disclosed application subject matter.

Claims

1. An automatic target changing system for replacing target components, characterized in that, include: A shielded container, the shielded container including a box and a first guide mechanism disposed on the box; A second guiding mechanism, the second guiding mechanism and the first guiding mechanism are configured to guide the movement of the target component; A releasable device is provided, wherein the first guide mechanism can be connected to the second guide mechanism via the releasable device, and when the target component moves to a preset position, the releasable device is configured to disconnect the connection between the first guide mechanism and the second guide mechanism.

2. The automatic target changing system according to claim 1, characterized in that, The releasable device includes a latching part and a moving part, the moving part being movable relative to the latching part, thereby connecting or disengaging the moving part from the latching part. The latching part is disposed on the second guide mechanism, and the moving part is disposed on the first guide mechanism; or, the latching part is disposed on the first guide mechanism, and the moving part is disposed on the second guide mechanism.

3. The automatic target changing system according to claim 2, characterized in that, When the target component moves to the preset position, the target component abuts against the moving part, thereby driving the moving part to move relative to the latching part to disconnect the connection between the first guide mechanism and the second guide mechanism.

4. The automatic target changing system according to claim 3, characterized in that, The target assembly includes a bracket and a target material. The bracket is used to carry the target material and can move along the second guide mechanism and the first guide mechanism. The bracket has a first end and a second end opposite to each other. The target material is disposed at the first end of the bracket. The second end of the bracket can abut against the moving part, thereby driving the moving part to move relative to the latching part to disconnect the connection between the first guide mechanism and the second guide mechanism.

5. The automatic target changing system according to claim 4, characterized in that, During the movement of the target assembly along the second guide mechanism, the second end of the bracket is always closer to the shielded container than the first end of the bracket; the second end of the bracket enters the shielded container before the first end of the bracket.

6. The automatic target changing system according to claim 2, characterized in that, The releasable device further includes a transmission component, and when the target assembly moves to a preset position, the releasable device is configured to disengage the moving part from the latching part via the transmission component.

7. The automatic target changing system according to claim 6, characterized in that, The shielded container further includes a second buffer device, which is disposed inside the shielded container. The preset position is when the target assembly moves along the first guide mechanism to a position where it contacts the second buffer device.

8. The automatic target changing system according to claim 1, characterized in that, When the first guide mechanism is connected to the second guide mechanism, at least a portion of the first guide mechanism is located outside the housing.

9. The automatic target changing system according to claim 1, characterized in that, After the first guiding mechanism is disconnected from the second guiding mechanism, the first guiding mechanism can move relative to the box body, thereby moving into the box body.

10. The automatic target changing system according to claim 1, characterized in that: The target assembly includes a bracket and a target material disposed on the bracket; The surface of the second guide mechanism that supports the bracket is configured as a guide surface. The guide surface extends continuously along the second guide mechanism, and the extension direction of the guide surface is consistent with the extension direction of the second guide mechanism. During the movement along the second guide mechanism, the target material is always located on the same side of the guide surface.

11. A neutron capture therapy system, characterized in that, The neutron capture therapy system includes: Accelerators are used to generate beams of charged particles. Target assembly, including a target material that reacts with a charged particle beam to generate a neutron beam; Beam shaper, used to modulate the energy spectrum of a neutron beam; A shielded container includes a housing and a first guiding mechanism disposed on the housing; A second guiding mechanism, the second guiding mechanism and the first guiding mechanism are configured to guide the movement of the target component; A releasable device is provided, wherein the first guide mechanism can be connected to the second guide mechanism via the releasable device, and when the target component moves to a preset position, the releasable device is configured to disconnect the connection between the first guide mechanism and the second guide mechanism.

12. The neutron capture therapy system according to claim 11, characterized in that, When the target component moves to the preset position, the target component drives the releasable device so that the releasable device disconnects the connection between the first guide mechanism and the second guide mechanism.

13. The neutron capture therapy system according to claim 11, characterized in that, The releasable device includes a latching part and a moving part. The moving part is movable relative to the latching part, thereby enabling the moving part to connect or disengage from the latching part. The latching part is disposed on the second guide mechanism, and the moving part is disposed on the first guide mechanism; or the latching part is disposed on the first guide mechanism, and the moving part is disposed on the second guide mechanism.

14. An automatic target changing system for replacing target components, characterized in that, include: A shielded container includes a housing and a first guiding mechanism disposed on the housing; A second guiding mechanism, the second guiding mechanism and the first guiding mechanism are configured to guide the movement of the target assembly, wherein at least a portion of the extension direction of the second guiding mechanism is not consistent with the extension direction of the first guiding mechanism; The first buffer device provides a buffering force to the target assembly as it moves along the second guide mechanism to the first guide mechanism.

15. The automatic target changing system according to claim 14, characterized in that, During the movement of the target assembly along the second guide mechanism to the first guide mechanism, the first buffer device can come into contact with the target assembly.

16. The automatic target changing system according to claim 15, characterized in that, As the target assembly enters the shielded container along the second guide mechanism and the first guide mechanism, a portion of the target assembly's structure is configured to have an overlapping motion trajectory that interferes with the first buffer device, so that the first buffer device abuts against the target assembly.

17. The automatic target changing system according to claim 16, characterized in that, The target assembly has a buffer braking part, the buffer braking part has a buffer braking surface, and the buffer braking surface is provided with at least two buffer braking positions; during the process of the target assembly entering the shielded container along the second guide mechanism and the first guide mechanism, the first buffer device sequentially abuts against each of the at least two buffer braking positions, and the at least two buffer braking positions that sequentially abut against the first buffer device form the mutually interfering overlapping motion trajectories.

18. The automatic target changing system according to claim 17, characterized in that, After the first buffer device comes into sequential contact with each of the at least two buffer braking positions, the first buffer device disengages from the target assembly.

19. The automatic target changing system according to claim 15, characterized in that, The first buffer device includes a first motion unit and a second motion unit. The first motion unit is disposed on the housing and can move relative to the housing. The second motion unit is disposed on the first motion unit and can move relative to the first motion unit. The second motion unit can contact or detach from the target assembly.

20. The automatic target changing system according to claim 19, characterized in that, The first motion unit can move along the extension direction of the first guide mechanism, and the second motion unit moves in a direction opposite to the extension direction of the first guide mechanism; or, The second motion unit can move along the extension direction of the first guide mechanism, while the movement direction of the first motion unit is opposite to the extension direction of the first guide mechanism.

21. The automatic target changing system according to claim 15, characterized in that, The first buffer device includes a support rod having a first end close to the direction of movement of the target assembly and a second end away from the direction of movement of the target assembly. The support rod has a preset rotation center located between its first end and second end. The first end of the support rod includes a support portion that abuts against the target assembly, and the second end of the support rod is connected to a power source.

22. A neutron capture therapy system, characterized in that, include: Accelerators are used to generate beams of charged particles. The target assembly includes a target material that reacts with the charged particle beam to generate a neutron beam; A beam shaper for adjusting the energy spectrum of the neutron beam; A shielded container includes a housing and a first guiding mechanism disposed on the housing; A second guiding mechanism is configured to guide the movement of the target assembly, wherein the extension direction of the second guiding mechanism is not consistent with the extension direction of the first guiding mechanism. The first buffer device provides a buffering force to the target assembly as it moves along the second guide mechanism to the first guide mechanism.

23. The neutron capture therapy system according to claim 22, characterized in that, Also includes: A releasable device is provided, wherein the first guide mechanism can be connected to the second guide mechanism via the releasable device, and when the target component moves to a preset position, the releasable device is configured to disconnect the connection between the first guide mechanism and the second guide mechanism.

24. The neutron capture therapy system according to claim 23, characterized in that, When the first guide mechanism is connected to the second guide mechanism, at least a portion of the first guide mechanism is located outside the housing; after the first guide mechanism is disconnected from the second guide mechanism, the first guide mechanism can move relative to the housing into the housing.

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