Perspiration measuring device and perspiration measuring system
The sweat measurement device with a hydrophilic-hydrophobic flow path and laminate structure addresses the challenge of inconsistent sweat supply, enabling continuous and stable sweat monitoring for health and exercise analysis.
Patent Information
- Application Number
- PCT/JP2025/028932
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-08-23
- Filing Date
- 2025-08-18
- Publication Date
- 2026-02-26
AI Technical Summary
Existing wearable sweat sensors struggle to continuously and stably measure sweat, particularly when the sweat production is low, due to inconsistent sweat supply.
A sweat measurement device with a flow path having regions of varying hydrophilicity, including hydrophilic and hydrophobic areas, promotes consistent sweat flow even at low production rates, using a laminate structure with adjustable hydrophilicity and stretchability for stable attachment to the skin.
Enables continuous and stable sweat measurement by ensuring consistent sweat flow, allowing for real-time monitoring of sweat components such as lactic acid and ions, supporting health and exercise condition assessment.
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Figure JP2025028932_26022026_PF_FP_ABST
Abstract
Description
Sweat measurement device and sweat measurement system
[0001] The present disclosure relates to a sweat measurement device and a sweat measurement system.
[0002] In recent years, various wearable sensors have been developed for the purpose of monitoring health conditions and exercise amounts. For example, a wearable sensor that measures the physical quantity of sweat is known (WO 2021 / 173546).
[0003] The amount of sweat produced by a person varies from light to heavy depending on the level of activity, etc. Therefore, it has been difficult to continuously and stably monitor sweat using a wearable device.
[0004] An object of one embodiment of the present disclosure is to provide a sweat measurement device and a sweat measurement system that can continuously and stably measure sweat.
[0005] Means for solving the above problems include the following aspects. <1> A sweat measurement device for measuring sweat emitted by a subject, comprising: an inlet through which sweat flows in; an outlet through which sweat flows out; a flow path connecting the inlet and the outlet; and a sensor for obtaining measurements of at least one of the sweat flow rate and components contained in the sweat, wherein an inner wall forming the flow path has a plurality of regions with different hydrophilicities at the same position in the flow direction. <2> The sweat measurement device according to <1>, wherein the plurality of regions include a hydrophilic region and a hydrophobic region. <3> The sweat measurement device according to <1> or <2>, wherein the sweat measurement device is constituted by a laminate of a plurality of layers. <4> The sweat measurement device according to any one of <1> to <3>, wherein the inner wall forming the flow path has a plurality of surfaces with different hydrophilicities. <5> The sweat measurement device according to any one of <1> to <4>, wherein the inner wall forming the flow path has hydrophilic surfaces at positions facing each other and hydrophobic surfaces at positions facing each other. <6> The sweat measurement device according to any one of <1> to <5>, which is stretchable and configured to be attachable to the skin of a subject. <7> The sweat measurement device according to any one of <1> to <6>, which is capable of continuous measurement over time. <8> The sweat measurement device according to any one of <1> to <7>, which includes a plurality of sensors. <9> The sweat measurement device according to any one of <1> to <8>, in which the measured value includes the amount or presence or absence of a component contained in sweat. <10> The sweat measurement device according to any one of <1> to <9>, in which the component contained in sweat is at least one of a compound and an ion contained in sweat. <11> The sweat measurement device according to any one of <1> to <10>, wherein the compound is at least one of a protein, cortisol, epinephrine, norepinephrine, dopamine, serotonin, thyroxine, glucose, uric acid, urea, bilirubin, creatinine, glyceraldehyde-3-phosphate, pyruvic acid, glyceric acid, lactic acid, estradiol, and testosterone. <12> The sweat measurement device according to <11>, wherein the protein is at least one of amylase, immunoglobulin A, brain-derived neurotrophic factor, interleukin-6, cardiac troponin T, tumor necrosis factor, and C-reactive protein.<13> The sweat measurement device according to any one of <1> to <12>, wherein the ion is at least one of sodium ions, potassium ions, calcium ions, magnesium ions, ammonium ions, iron ions, zinc ions, bicarbonate ions, phosphate ions, and chloride ions. <14> The sweat measurement device according to any one of <1> to <13>, wherein the measured value is a lactic acid level. <15> A sweat measurement system comprising the sweat measurement device according to any one of <1> to <14>. <16> The sweat measurement system according to <15>, comprising an analysis unit that analyzes the measured value. <17> The sweat measurement system according to <16>, wherein the analysis unit determines a danger value by analyzing the measured value, and issues a danger signal in accordance with the determination.
[0006] Fig. 1 is a schematic cross-sectional view showing an example of a cross section of the perspiration measurement device 10. Fig. 2 is an explanatory diagram illustrating the configuration of the perspiration measurement device 10. Fig. 3 is a schematic cross-sectional view showing an example of a cross section of the flow path taken along line AA in Fig. 1. Fig. 4 is a block diagram showing an example of the hardware configuration of a calculation processing device. Fig. 5 is a block diagram showing an example of the functional configuration of the calculation processing device.
[0007] An example of an embodiment of the present disclosure will be described below with reference to the drawings. In each drawing, the same or equivalent components and parts are designated by the same reference numerals. Furthermore, the dimensional proportions in the drawings are exaggerated for the sake of explanation and may differ from the actual proportions.
[0008] <Sweat Measurement Device> A sweat measurement device according to an embodiment of the present disclosure is a sweat measurement device that measures sweat emitted by a subject, and includes an inlet through which sweat flows in, an outlet through which sweat flows out, a flow path that connects the inlet and the outlet, and a sensor that obtains a measurement value of at least one of the sweat flow rate and a component contained in the sweat. The inner wall that forms the flow path has a plurality of regions with different hydrophilicities at the same position in the flow direction.
[0009] The background to the development of one embodiment of the present disclosure will be described. A printed sweat measurement device that is attached to the skin of a subject to measure the components of the subject's sweat is lightweight, inexpensive, can be printed on a variety of materials, and can non-invasively quantify components such as lactic acid in sweat. This device makes it possible to continuously monitor components such as lactic acid levels in a subject's sweat over long periods of time. However, when the sweat rate is low, this device may not provide a stable supply of sweat, making it impossible to continuously monitor changes in the measurement value.
[0010] The inventors have conducted extensive research into a sweat measurement device that can measure sweat even when the amount of sweat produced is small and can continuously and stably measure sweat. They focused on the sweat flow path in the sweat measurement device and found that by adjusting the hydrophilicity of the inner wall of the flow path and providing multiple regions with different hydrophilicity at the same position in the flow direction, the flow path can be made to allow sweat to flow easily even when the amount of sweat produced is small. This has resulted in a sweat measurement device that can continuously and stably supply sweat to the device, whether the amount of sweat produced is small or large.
[0011] The mechanism by which the above effect is achieved is unclear, but it is speculated that this is because the flow of sweat within the sweat flow path in the sweat measurement device is promoted by adjusting the hydrophilicity of the inner walls that form the flow path.
[0012] As shown in FIG. 1, a sweat measurement device 10 according to an embodiment of the present disclosure may include a tape member 11a, an elastic member 12a, an elastic member 12b, an elastic member 12c, a tape member 11b, and a flexible substrate 13 stacked in this order.
[0013] The tape member has adhesive properties. More specifically, the tape member may be a nonwoven fabric substrate with adhesive applied to both sides. That is, double-sided tape may be used as the tape member. In the tape member 11a to be attached to the skin, one adhesive may be attached to the subject's skin. The tape member 11a may be formed with an exposed portion 16 that exposes the opening 15. The other adhesive may be attached to the elastic member 12a. The tape member to which the flexible substrate is attached may be double-sided tape. Like the tape member 11a, the tape member 11b may be formed with an exposed portion for allowing sweat Sw to flow to a sensor (not shown) arranged on the flexible substrate 13.
[0014] The elastic members 12a, 12b, and 12c are layered between the tape members 11a and 11b. The elastic members 12a, 12b, and 12c may have flow paths 17 through which sweat flows, formed, for example, parallel to the layered surface. The openings 15 may be connected to the flow paths 17. As a result, sweat Sw produced by the subject flows through the flow paths 17 via the exposed portions 16 and the openings 15. The amount of sweat Sw flowing through the flow paths 17 can be adjusted by changing the size of the exposed portions 16.
[0015] The elastic member may be formed of, for example, an elastomer. An elastomer is a soft polymer that has elasticity like rubber. Examples of elastomers include silicone elastomers such as PDMS (Polydimethylsiloxane). The flow channel 17 may be, for example, a micro-flow channel formed finely in such PDMS.
[0016] A sensor element (not shown) is arranged on the flexible substrate 13, and measures the sweat flowing through the flow path 17. The flexible substrate 13 includes a sensor. The flexible substrate 13 is protected by a protective member (not shown). The protective member may be made of PDMS or the like, similar to the elastic member. These layers may also be formed by printing.
[0017] In this way, the perspiration measurement device may be configured by laminating flexible members, which allows the perspiration measurement device to be in close contact with the skin, thereby achieving a high wearing comfort and high measurement accuracy.
[0018] The flow channel 17 is a so-called micro flow channel, and can allow sweat Sw to flow appropriately within the flow channel 17 even when the amount of sweat is small, for example, 3 μL / min.
[0019] The multiple regions on the inner wall having different hydrophilicities preferably include a hydrophilic region and a hydrophobic region. By including a hydrophilic region and a hydrophobic region at the same position in the flow direction on the inner wall of the flow channel, the flow of sweat within the flow channel is more appropriately promoted. The hydrophilic region and the hydrophobic region may be located at the same position in the flow direction. Furthermore, the inner wall forming the flow channel may have not only two types of regions, a hydrophilic region and a hydrophobic region, but also three or more types of regions with different hydrophilicities.
[0020] The sweat measurement device is preferably constructed of a laminate of multiple layers. This allows the flow path to be formed by laminating multiple elastic members, etc., and the inner wall forming the flow path to be formed by an elastic member. Therefore, the hydrophilicity of the inner wall forming the flow path can be controlled by subjecting each of the multiple elastic members to hydrophilic or hydrophobic treatment.
[0021] As shown in FIG. 2 , the sweat measurement device 10 may include a tape member 11a, an elastic member 12a, an elastic member 12b, an elastic member 12c, a tape member 11b, and a flexible substrate 13, in this order. At least the elastic members 12a, 12b, and 12c form a flow path 17. Each of these elastic members has a space where no member is formed, and the flow path 17 can be formed by combining the space portions. The region of the elastic member that forms the flow path 17 becomes the inner wall of the flow path 17. Furthermore, by making at least a portion of each of these elastic members hydrophilic or hydrophobic, the flow path 17 can be made to have controlled hydrophilicity. In this way, by forming the flow path 17 using an elastic member whose hydrophilicity has been adjusted, the shape of the flow path 17 or different hydrophilicity in the flow path 17 can be adjusted.
[0022] "Hydrophilicity" refers to the property of being easily compatible with water and easily wetted, and the degree of this property can be expressed by the contact angle with water (hereinafter sometimes simply referred to as "water contact angle"). To be hydrophilic, the contact angle with water on the surface of an object is preferably 90 degrees or less, more preferably 60 degrees or less, and most preferably 30 degrees or less. The water contact angle refers to the angle between the surface and the liquid surface when water is dropped onto the surface of the object being measured. A larger angle indicates that the surface is less wetted by water, and a smaller angle indicates that the surface is more wetted by water. The water contact angle is measured using a goniometer or the like. Specifically, the contact angle after dropping water on the surface of the object in an environment of 23°C and 55% RH and leaving it for 60 seconds is measured using a contact angle measuring device CA-X (manufactured by Kyowa Interface Science Co., Ltd.). "Hydrophobicity" refers to the property of being less compatible with water and less wetted, and can be explained as the opposite of the property described above regarding hydrophilicity.
[0023] The method for making the elastic member hydrophilic is not particularly limited, and conventionally known methods can be employed. Various methods, such as various surface treatments and the application of coating agents, may be employed depending on the purpose. For example, a method of applying a superhydrophilic coating to the elastic member can be used. In this method, the elastic member forming the inner wall of the flow path 17 is degreased, UV ozone treated, coated with a superhydrophilic coating agent, and thermally dried in this order. This imparts hydrophilicity to the elastic member. In the above process, the UV ozone treatment generates SiOH groups on the surface of the elastic member. Then, by applying a superhydrophilic coating agent, the compounds of the superhydrophilic coating are properly aligned on the surface, resulting in an elastic member with more appropriate hydrophilicity.
[0024] The inner wall forming the flow path preferably has multiple surfaces with different hydrophilicities. The multiple surfaces may be two or more, and the inner wall forming the flow path preferably has two or more surfaces with different hydrophilicities. "Different hydrophilicities" refers to different degrees of water compatibility and wettability. The hydrophilicity is the same as described above. Within the flow path, sweat tends to flow more smoothly when it comes into contact with a surface. Therefore, if the inner wall forming the flow path has a surface with higher hydrophilicity than other surfaces, sweat can flow more easily along that surface through the flow path, thereby controlling the flow of sweat. For example, by making the surface of the inner wall in contact with the flexible substrate equipped with the sensor more hydrophilic than other surfaces, sweat can flow more stably to the sensor.
[0025] The inner walls forming the flow path preferably have hydrophilic surfaces facing each other and hydrophobic surfaces facing each other. This allows sweat to flow easily along the surfaces. By providing, for example, a sensor or a sweat outlet along the hydrophilic surfaces, sweat that has flowed into the device is easily guided to the sensor or the sweat outlet. The outlet may be configured as an open opening at the downstream end of the flow path.
[0026] As shown in FIG. 3 , the inner walls 21, 22, 23, and 24 that form the flow path 17 have hydrophilic surfaces on the inner walls 22 and 24, and hydrophobic surfaces on the inner walls 21 and 23. The inner walls that form the flow path 17 have multiple regions with different hydrophilicities at the same position in the flow direction. The multiple regions with different hydrophilicities may be located at the same position in the flow direction. "The same position in the flow direction" refers to a position in a direction perpendicular to the flow direction. That is, it refers to a position on the same cross section perpendicular to the flow direction (a plane substantially perpendicular to the flow direction). Note that the "perpendicular direction" may be substantially perpendicular, but may not be exactly perpendicular. Therefore, among the inner walls 21, 22, 23, and 24 that form the flow path 17, the hydrophilic inner walls 22 and 24 and the hydrophobic inner walls 21 and 23 are located at the same position in the flow direction. Furthermore, it is sufficient that a part of the entire flow channel 17 has a plurality of regions with different hydrophilicities, and the entire flow channel 17 may have such a structure.
[0027] When hydrophilic surfaces are provided in positions facing each other and hydrophobic surfaces are provided in positions facing each other, sweat tends to flow through the center of the flow path, and even when the amount of sweat is small, sweat is prevented from being divided and retained on the wall surfaces of the inner walls, etc. of the flow path, and the flow of sweat through the flow path is promoted.
[0028] It is also preferable that only the inner wall 22 has a hydrophilic surface, and the inner walls 21, 23, and 24 have hydrophobic surfaces. When there is only one hydrophilic surface, sweat Sw tends to flow along the hydrophilic surface and through the center of the flow path 17, and even when the amount of sweating is small, sweat is prevented from being divided and retained on the wall surfaces of the inner walls 21, 23, etc., and the flow of sweat Sw through the flow path 17 is promoted.
[0029] The perspiration measurement device is preferably stretchable and configured to be attachable to the skin of a subject. All of the members constituting the perspiration measurement device can be stretchable. Therefore, the perspiration measurement device can also be stretchable.
[0030] To improve the stretchability of the sweat measurement device, for example, the sensor can be manufactured using a TPU (Thermoplastic Polyurethane) film substrate, stretchable silver paste, stretchable carbon paste, stretchable insulating paste, etc. For example, even when a sensor including these configurations is stretched 40% in the longitudinal direction from an unloaded state, a sudden increase in the resistance value of the silver wiring is unlikely to occur. Furthermore, because all components, including the sensor, can be stretched, cracks are unlikely to occur in the sweat measurement device 10.
[0031] It is preferable that the sweat measurement device be capable of continuous measurement over time. Because the sweat measurement device is stretchable, it can be stably attached to the skin of a subject for an extended period of time. Therefore, it is possible to continuously monitor the sweat of a subject over time.
[0032] The sweat measurement device preferably includes multiple sensors. This allows multiple biological parameters to be obtained in real time based on the subject's sweat. This data can be useful for understanding the subject's health condition, or for understanding an athlete's exercise intensity, fatigue level, etc.
[0033] The measured value preferably includes the amount or presence or absence of components contained in sweat. The measured value obtained by the sensor may be not only the amount of sweat but also the amount of components contained in sweat, the presence or absence of components contained in sweat, etc. The measured value can be obtained in real time, and therefore provides useful data.
[0034] The component of sweat measured by the sensor is preferably at least one of compounds and ions contained in sweat. The sensor provided in the sweat measurement device can preferably measure at least one of compounds and ions contained in sweat.
[0035] Among the sweat components measured by the sensor, the following compounds are preferred. That is, the compound is preferably at least one of protein, cortisol, epinephrine, norepinephrine, dopamine, serotonin, thyroxine, glucose, uric acid, urea, bilirubin, creatinine, glyceraldehyde-3-phosphate, pyruvic acid, glyceric acid, lactic acid, estradiol, and testosterone. These compounds are useful for understanding the subject's health condition, exercise intensity, fatigue level, etc.
[0036] The protein is preferably at least one of amylase, immunoglobulin A, brain-derived neurotrophic factor, interleukin-6, cardiac troponin T, tumor necrosis factor, and C-reactive protein. These compounds are useful for understanding the health condition, exercise intensity, fatigue level, etc. of a subject.
[0037] Among the sweat components measured by the sensor, the following ions are preferred. That is, the ions are preferably at least one of sodium ions, potassium ions, calcium ions, magnesium ions, ammonium ions, iron ions, zinc ions, bicarbonate ions, phosphate ions, and chloride ions. These compounds are useful for understanding the subject's health condition, exercise intensity, fatigue level, etc.
[0038] The sweat measurement device can measure one or more components selected from those listed above using a sensor. By combining one or more of these components, it is possible to obtain continuous, stable real-time measurements, making the sweat measurement device useful for a variety of purposes.
[0039] The measurement value measured by the sweat measurement device is preferably the lactate level. Exercise intensity or fatigue level can be evaluated from the lactate level in body fluids. The sweat measurement device can accurately measure lactate levels. This makes it possible to grasp the athlete's health condition, exercise intensity, etc. in real time.
[0040] The accuracy and reliability of the lactate value measurements taken by the sweat measurement device 10 were confirmed as follows. That is, a sweat measurement device 10 for measuring sweat rate, lactate concentration in sweat, and sweat pH was prepared, attached to the arm of a subject, and the subject exercised on a fitness bike while varying the load intensity over time, and the reliability of the measurements taken by the sweat measurement device 10 was evaluated. The subject's body temperature, heart rate, and blood or interstitial lactate concentration were also measured simultaneously, and the increases and decreases in exercise load were plotted against the blood or interstitial lactate concentration and the lactate concentration measured by the sweat measurement device 10 for comparison. As a result, the trends of these increases and decreases were consistent, confirming the accuracy and reliability of the lactate concentration measurements taken by the sweat measurement device 10.
[0041] <Sweat Measurement System> One embodiment of the present disclosure is a sweat measurement system including a sweat measurement device according to one embodiment of the present disclosure. The sweat measurement system includes a processing unit.
[0042] As shown in Fig. 4, an arithmetic processing device 300 according to an embodiment of the present disclosure processes a detection signal input from a sensor (not shown) and outputs a measurement result related to sweat. The arithmetic processing device 300 may be a computer. More specifically, the arithmetic processing device 300 may include a processor 301, a read-only memory (ROM) 302, a random access memory (RAM) 303, a storage 304, a communication interface 305, and a user interface 306. These components are connected to each other via a bus 309 so as to be able to communicate with each other.
[0043] The processor 301 executes various programs and controls each component. Here, the processor 301 is assumed to be a CPU (Central Processing Unit). The ROM 302 stores various programs and various data. The RAM 303 temporarily stores programs or data as a working area. The storage 304 is configured with an HDD (Hard Disk Drive) or an SSD (Solid State Drive) and stores various programs including an operating system and various data.
[0044] In the arithmetic processing device 300 according to this embodiment, an arithmetic processing program is stored in the ROM 302 or the storage 304. The processor 301 reads the arithmetic processing program from the ROM 302 or the storage 304 and executes it using the RAM 303 as a working area, thereby controlling each component and executing various arithmetic processing in accordance with the arithmetic processing program.
[0045] The communication interface 305 is an interface through which the arithmetic processing device 300 communicates with other devices (including sensors). The user interface 306 is an input / output interface through which the arithmetic processing device 300 exchanges information with a user. The user interface 306 may include input devices such as a mouse, keyboard, touch panel, and microphone, and output devices such as a monitor and speaker.
[0046] 5 is a diagram showing an example of the functional configuration of the arithmetic processing device 300 according to this embodiment. The arithmetic processing device 300 includes an acquisition unit 310, a calculation unit 320, and an output unit 330. These functional configurations are realized by the processor 301 reading and executing an arithmetic processing program stored in the ROM 302 or the storage 304.
[0047] The acquisition unit 310 acquires detection signals output by the sensors. The acquisition unit 310 may acquire detection signals output by, for example, a sensor that measures sweat flow rate, a sensor that detects various components, etc.
[0048] The calculation unit 320 measures various biological parameters, including the amount of sweat, based on the detection signals acquired by the sensors. The output unit 330 outputs measurement results according to the measurements taken by the calculation unit 320. The output unit 330 may, for example, display the measurement results on a monitor, output them as audio through a speaker, or transmit them to another device.
[0049] The arithmetic processing device 300 is an example of an analysis unit that analyzes data. The sweat measurement system according to an embodiment of the present disclosure preferably includes an analysis unit that analyzes the measurement values.
[0050] Preferably, the analysis unit analyzes the measurement values to determine the danger value and issues a danger signal in accordance with the determination. The output unit 330 outputs various signals, such as danger signals, based on the measurement results obtained by the calculation unit 320, which is an example of an analysis unit. The calculation unit 320 functions as an analysis unit.
[0051] The sweat measurement device measures the subject's sweat, and can immediately notify the subject or others if, for example, the subject is at high risk of heat stroke. The sweat measurement device is in the form of a thin film tape and can be activated by being attached to the subject's body, which is useful because it places little strain on the subject and provides continuous, stable acquisition of useful data.
[0052] The above-described processing can also be realized by a dedicated hardware circuit. In this case, the processing may be performed by a single piece of hardware or by multiple pieces of hardware.
[0053] In the above description, the processor 301 refers to a processor in a broad sense, and includes a general-purpose processor (e.g., CPU: Central Processing Unit, etc.) and a dedicated processor (e.g., GPU: Graphics Processing Unit, ASIC: Application Specific Integrated Circuit, FPGA: Field Programmable Gate Array, programmable logic device, etc.).
[0054] Furthermore, the operations of the processor 301 described above may not only be performed by a single processor, but may also be performed by multiple processors located at physically separate locations working together. Furthermore, the order of the operations of the processor 301 is not limited to the order described above, and may be changed as appropriate.
[0055] The above-mentioned arithmetic processing program may be provided by a computer-readable non-transitory recording medium such as a USB (Universal Serial Bus) memory, a flexible disk, or a CD-ROM (Compact Disc Read Only Memory), or may be provided online via a network such as the Internet. In this case, the arithmetic processing program recorded on the computer-readable non-transitory recording medium is usually transferred to and stored in a memory or storage. The arithmetic processing program may be provided as standalone application software, or may be incorporated into the software of each device as a function of the device.
[0056] The above-described arithmetic processing program can be provided as a program product. The program product includes any type of product for providing a program. For example, the program product includes a program provided via a network such as the Internet, and a non-transitory computer-readable recording medium such as a CD-ROM or DVD on which the program is stored.
[0057] The present disclosure is not limited to the above, and it goes without saying that various modifications can be made without departing from the spirit of the present disclosure.
[0058] The disclosure of Japanese Patent Application No. 2024-143473, filed on August 23, 2024, is incorporated herein by reference in its entirety. All documents, patent applications, and technical standards mentioned herein are incorporated herein by reference to the same extent as if each individual document, patent application, and technical standard was specifically and individually indicated to be incorporated by reference.
Claims
1. A sweat measurement device for measuring sweat emitted by a subject, comprising: an inlet through which the sweat flows; an outlet through which the sweat flows; a flow path connecting the inlet and the outlet; and a sensor for obtaining measurements of at least one of the flow rate of the sweat and a component contained in the sweat, wherein the inner wall forming the flow path has a plurality of regions with different hydrophilicity at the same position in the flow direction.
2. The sweat measurement device according to claim 1, wherein the plurality of regions include hydrophilic regions and hydrophobic regions.
3. The sweat measuring device according to claim 1, which is constructed from a laminate of multiple layers.
4. The sweat measurement device according to claim 1, wherein the inner wall forming the flow path has a plurality of surfaces with different hydrophilicities.
5. A sweat measurement device according to claim 1, wherein the inner walls forming the flow path have hydrophilic surfaces facing each other and hydrophobic surfaces facing each other.
6. The sweat measurement device according to claim 1, which is stretchable and configured to be attachable to the skin of the subject.
7. The sweat measurement device according to claim 1, which is capable of continuous measurement over time.
8. The sweat measurement device according to claim 1, comprising a plurality of the sensors.
9. The sweat measurement device according to claim 1, wherein the measurement value includes the amount or presence or absence of a component contained in the sweat.
10. The sweat measurement device according to claim 1, wherein the component contained in the sweat is at least one of a compound and an ion contained in the sweat.
11. The sweat measurement device of claim 10, wherein the compound is at least one of a protein, cortisol, epinephrine, norepinephrine, dopamine, serotonin, thyroxine, glucose, uric acid, urea, bilirubin, creatinine, glyceraldehyde-3-phosphate, pyruvic acid, glyceric acid, lactic acid, estradiol, and testosterone.
12. The sweat measurement device according to claim 11, wherein the protein is at least one of amylase, immunoglobulin A, brain-derived neurotrophic factor, interleukin-6, cardiac troponin T, tumor necrosis factor, and C-reactive protein.
13. The sweat measurement device according to claim 10, wherein the ions are at least one of sodium ions, potassium ions, calcium ions, magnesium ions, ammonium ions, iron ions, zinc ions, bicarbonate ions, phosphate ions, and chloride ions.
14. The sweat measurement device according to claim 1, wherein the measurement value is a lactate value.
15. A sweat measurement system comprising the sweat measurement device according to any one of claims 1 to 14.
16. The sweat measurement system according to claim 15, further comprising an analysis unit for analyzing the measurement value.
17. The sweat measurement system according to claim 16, wherein the analysis unit determines a danger value by analyzing the measurement value, and issues a danger signal in response to the determination.
Citation Information
Patent Citations
Gel sensor and measuring device
JP2017063929A
Wearable sensor and perspiration analysis apparatus
JP2020171350A
Wearable biofluid volume and composition measurement system
JP2023099322A
Multilayer adhesive fluid collection article containing capillary channels - Patents.com
JP2023507406A