Insecticidal proteins compositions and methods of use

WO2026055006A3 Publication Date: 2026-05-15GENECTIVE SA
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Patent Information

Application Number
PCT/US2025/043320
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-09-03
Filing Date
2025-08-25
Publication Date
2026-05-15

AI Technical Summary

Technical Problem

Current pesticidal proteins derived from Bacillus thuringiensis are facing resistance issues in target pests, necessitating the development of novel insecticidal proteins with new modes of action to effectively control plant pests.

Method used

The use of engineered polypeptides with at least 95% sequence identity to SEQ ID NOs: 1-14, which are expressed in transgenic plants to provide pesticidal activity against various plant pests, including specific insects and pathogens.

Benefits of technology

The engineered polypeptides offer effective pest control by conferring resistance to plant pathogens and pests, providing an alternative to existing resistant strains.

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Abstract

Disclosed herein are transformed plants, plant tissues, plant parts, plant cells, and plant seeds comprising a recombinant nucleic acid molecule encoding a polypeptide having pesticidal activity. Also disclosed herein are methods of protecting or treating a plant from infection by a plant pathogen or pest by transforming plants, plant tissues, plant parts, plant cells, and plant seeds with a recombinant nucleic acid molecule encoding a polypeptide having pesticidal activity.
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