Blood pump

Abstract

The present invention relates to a blood pump (10) comprising a pumping section (12) configured to be placed in a human body, a cable (20) and a connector (40). The cable (20) comprises a distal end (42), a proximal end (44), a first portion (46) and a second portion (48). The distal end (42) of the cable (20) is connected to the pumping section (12) and the proximal end (44) of the cable (20) is connected to the connector (40). The first portion (46) has a first diameter (DM1) and the second portion (48) has a second diameter (DM2). The first diameter (DM1) is different from the second diameter (DM2), wherein the first diameter (DM1) is preferably smaller than the second diameter (DM2). The first portion (46) preferably is a skin passage portion and the second portion (48) preferably is an extracorporeal portion.

Description

[0001] New PCT Application Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0002] 1 / 25

[0003] BLOOD PUMP

[0004] The present invention relates to a blood pump. In particular, the present invention relates to an intravascular blood pump for percutaneous insertion into a patient’s blood vessel, to support a blood flow in a patient’s blood vessel. The blood pump may also be an intracardiac blood pump or any other kind of ventricular assist device.

[0005] BACKGROUND OF THE INVENTION

[0006] Various blood pumps are known from the prior art e.g., axial blood pumps, centrifugal (i.e. , radial) blood pumps or mixed-type blood pumps, where the blood flow is caused by axial forces as well as by radial forces. The blood pump can be advanced through a patient’s blood circulatory system, i.e., veins and / or arteries, to a position in the patient’s heart or elsewhere within the patient’s vasculature. Such a blood pump is typically disposed at the end of a catheter, which is used to insert and position the pump, and later to withdraw the pump. Once in position, the pump may be used to pump blood through the circulatory system and, therefore, temporarily reduce workload on the patient’s heart, such as to enable the heart to recover after a heart attack.

[0007] Therefore, a blood pump typically comprises a pumping section with a pump housing having a blood flow inlet and a blood flow outlet connected by a blood flow passage, a pump element in form of an impeller disposed in said pump housing being rotatable about an axis of rotation for conveying blood from the blood flow inlet to the blood flow outlet along the blood flow passage. Further, such blood pumps comprise a drive unit configured to rotate the impeller.

[0008] In some blood pumps, the drive unit is part of the pumping section and is thus also placed within the human body. To energize and control the drive unit, a cable is attached to the pumping section which exits the human body via an exit site. Therefore, the cable penetrates through the skin and is further connected to a suitable energy source.

[0009] To allow the patient a certain degree of mobility, it is advisable to use a portable energy source, such as a rechargeable battery. In doing so, it needs to be warranted that dissipated power due to the cable’s electrical resistance is as low as possible. Hence, it is therefore advantageous to use a cable with a relatively large cross section and therefore relatively low electrical resistance. On the other hand, a cable with a relatively large cross section may be problematic in terms of the skin transition, as this will favor infections and may lead to inflamed tissue in the area of the exit site.

[0010] Accordingly, there is the need for an ameliorated blood pump having low power dissipation and a reduced risk of inflammation. New PCT Application

[0011] Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0012] 2 / 25

[0013] SUMMARY OF THE INVENTION

[0014] According to a first aspect, a blood pump comprises a pumping section, a cable and a connector. The pumping section is configured to be placed in a human body. The cable comprises a distal end and a proximal end. The distal end of the cable may be connected to the pumping section and the proximal end of the cable may be connected to the connector. The cable further comprises a first portion and a second portion. The first portion may have a first diameter and the second portion may have a second diameter. The first diameter may be different from the second diameter. Preferably, the first diameter is smaller than the second diameter. The first portion is preferably a skin passage portion and the second portion is preferably an extracorporeal portion.

[0015] Thus, that portion of the cable which penetrates through the skin has a reduced first diameter which thus reduces the risk of infections or inflammations. Another portion of the cable, which is preferably the extracorporeal portion running outside of the human body when the pumping section is placed in the human body, has a larger second diameter which thus reduces the power dissipation as the electrical resistance is reduced. The smaller first diameter is therefore locally limited to the area of skin passage so that the increased electrical resistance due to the smaller diameter is of minor influence regarding the total electrical resistance of the cable.

[0016] Herein, "proximal" and "distal" are seen relative to the physician. Thus, proximal designates something which is relatively close to the physician whereas distal designates something which is relatively far away from the physician when the blood pump is placed at the designated position within the human body.

[0017] The first portion may constitute between 1% and 50% of the cable. Preferably, the first portion may constitute between 2% and 30% of the cable. Even more preferably, the first portion may constitute between 3% and 30% of the cable. Most preferably, the first portion may constitute between 4% and 10% of the cable. The first diameter may be between 30% and 80% of the second diameter. Preferably, the first diameter may be between 40% and 70% of the second diameter. Even more preferably, the first diameter may be between 45% and 60% of the second diameter. Most preferably, the first diameter may be between 45% and 55% of the second diameter.

[0018] The first portion may be disposed between the distal end and the second portion. The second portion may be disposed between the proximal end and the first portion.

[0019] The cable may comprise a first tapered portion. The first tapered portion may be disposed between the first portion and the second portion. The first tapered portion may taper from the second diameter to the first diameter. The first tapered portion allows for a smooth transition between the first portion and New PCT Application

[0020] Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0021] 3 / 25 the second portion. This prevents the cable from getting caught or snagged at the connection between the first portion and the second portion when the cable is moved.

[0022] The cable may comprise a third portion disposed between the first portion and the distal end. The third portion has a third diameter. The third diameter may be larger than the first diameter. The third diameter may be identical to the second diameter. The third portion may be an intracorporeal portion. As such, the third portion may be disposed within the human body when the pumping section is placed in the human body. As the third portion may have a larger third diameter than the first diameter, which reduces the electrical resistance and hence the power dissipation. Furthermore, as the third portion is not disposed in the area of the skin passage when the pumping section is placed in the human body, it may have a larger diameter than the first portion, as there is no increased risk of infections or inflammations due to the third diameter being larger than the first diameter. That is because the third portion will not sit across the skin transition and will also not pass through the skin.

[0023] The cable may comprise a second tapered portion. The second tapered portion may be disposed between the first portion and the third portion, and the second tapered portion may taper from the third diameter to the first diameter. The second tapered portion allows for a smooth transition between the first portion and the third portion. This prevents the cable from getting caught or snagged at the connection between the first portion and the third portion when the cable is moved.

[0024] The cable may comprise a fourth portion disposed between the third portion and the distal end. The fourth portion may be an intravascular portion. The fourth portion has a fourth diameter and the fourth diameter may be smaller than the second diameter. As the intravascular portion is at least in parts disposed within the vasculature of the human body when the pumping section is placed within the human body, the relatively small fourth diameter is advantageous to avoid injuries or blockades of the vasculature.

[0025] The cable may comprise a third tapered portion. The third tapered portion may be disposed between the fourth portion and the third portion and the third tapered portion may taper from the third diameter to the fourth diameter. The third tapered portion allows for a smooth transition between the fourth portion and the third portion. This prevents the cable from getting caught or snagged at the connection between the fourth portion and the third portion when the cable is moved.

[0026] The fourth portion may have a higher stiffness than the first portion. The fourth portion may have a higher stiffness than the second portion. The fourth portion may have a higher stiffness than the third portion. Providing an intravascular portion with a higher stiffness is advantageous in terms of advancing the pumping section along the vasculature or in terms of repositioning of the placed pumping section. The higher stiffness of the fourth portion allows for a facilitated placement of the pumping section within the human body, as the fourth portion is thus stiff and rotatable enough to New PCT Application

[0027] Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0028] 4 / 25 maneuver the pumping section through e.g., a hemostasis valve, along the bends within the vasculature and through the aortic valve into the left ventricle.

[0029] A barrier may be disposed about the first portion. The barrier may comprise an anti-bacterial agent. When the pumping section is placed in the human body, the barrier disposed about the first portion penetrates through the skin of the patient, whereby the anti-bacterial agent reduces the risk of infections and inflammations. Therefore, the barrier is preferably at least partially composed of a porous fleece material e.g., Dacron velour, so that tissue ingrowth is prevented.

[0030] The first portion may comprise at least one first wire and the second portion may comprise at least one second wire. The at least one first wire may have a different diameter than the at least one second wire. Preferably, the diameter of the first wire is smaller than the diameter of the second wire. Reducing the diameter of the at least one first wire compared to the diameter of the at least one second wire allows the first diameter of the cable to be smaller than the second diameter of the cable.

[0031] The first portion may comprise Ni first wires and the second portion may comprise N2 second wires, whereby N1 denotes the number of first wires and N2 denotes the number of second wires. N1 is equal or larger than 1 and N2 is larger than N1 and larger or equal than 2. Preferably, N1 and N2 are a multiple of 3. Hence, the first portion may for instance comprise three first wires and the second portion may for instance comprise six second wires. Reducing the number of wires in the first portion allows the first diameter of the cable to be smaller than the second diameter of the cable.

[0032] The third portion may comprise at least one third wire. The at least one third wire may have a larger diameter than the at least one first wire. The diameter of the at least one third wire is preferably identical to or larger than the diameter of the at least one second wire. The third portion may comprise N3 third wires, whereby N3 denotes the number of third wires. N3 may be larger than N1 and may be equal or larger than 2. N3 may be a multiple of 3. Preferably, N3 is identical to N2.

[0033] The fourth portion may comprise at least one fourth wire. The at least one fourth wire may have a smaller diameter than the at least one second wire. The fourth portion may comprise N4 fourth wires, whereby N4 denotes the number of fourth wires. N4 may be equal or larger than 1 and may be identical to N1. N4 may be a multiple of 3.

[0034] The at least one first wire is preferably an electrical wire. The at least one second wire is preferably an electrical wire. The at least one third wire is preferably an electrical wire. The at least one fourth wire is preferably an electrical wire.

[0035] The cable may comprise at least one optical fiber. Preferably, the cable comprises at least two optical fibers. The cable may further comprise at least one lumen. The at least one optical fiber may be disposed within the at least one lumen. The at least one lumen may be a purge lumen configured to allow a purge New PCT Application

[0036] Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0037] 5 / 25 solution to be delivered to the pumping section. Of course, the cable may comprise a purge lumen and a further lumen with the at least one optical fiber or the at least two optical fibers respectively disposed therein. The at least one lumen may have a smaller diameter in the first portion than in the second portion.

[0038] The cable may comprise a sheathing or coating as a radially outermost layer. The sheathing or coating may be of a highly biocompatible material. The sheathing or coating may have a first wall thickness in the first portion and a second wall thickness in the second portion. The first wall thickness may be smaller than the second wall thickness. The sheathing or coating may have a third wall thickness in the third portion and a fourth wall thickness in the fourth portion. The third wall thickness may be larger than the first wall thickness and may be equal to the second wall thickness. The fourth wall thickness may be smaller than the second wall thickness. Varying the wall thickness of the sheathing or coating about the length of the cable allows the first diameter to be smaller than the second diameter.

[0039] The first diameter may be between 2 mm and 3 mm, wherein the first diameter is preferably smaller than 3 mm. The first diameter may be between 2.5 mm and 2.9 mm. Preferably, the first diameter is 2.8 mm. The second diameter may be between 3 mm and 6 mm, wherein the second diameter is preferably larger than 3 mm. The second diameter may be between 5.0 mm and 5.5 mm. Preferably, the second diameter is 5.3 mm. The third diameter may be between 3 mm and 6 mm, wherein the third diameter is preferably larger than 3 mm. The third diameter may be between 5.0 mm and 5.5 mm, wherein the third diameter is preferably 5.3 mm. The fourth diameter may be between 2 mm and 3 mm, wherein the fourth diameter is preferably smaller than 3 mm. The fourth diameter may be between 2.5 mm and 2.9 mm, wherein the fourth diameter is preferably 2.8 mm.

[0040] Having only the first portion or skin passage portion respectively provided with a reduced diameter instead of having a reduced diameter for the entire cable greatly reduces the cable resistance. In other words, portions of the cable with an enlarged diameter have reduced cable resistance compared to those portions with a reduced diameter. The portions with the reduced diameter, on the other hand, are beneficial in terms of infections, inflammations and placement of the pumping section as described above.

[0041] BRIEF DESCRIPTION OF THE DRAWINGS

[0042] The foregoing summary as well as the following detailed description of preferred embodiments will be better understood when read in conjunction with the appended drawings. For the purpose of illustrating the present disclosure, reference is made to the drawings. However, the scope of the disclosure is not limited to the specific embodiments disclosed in the drawings. New PCT Application

[0043] Abiomed Europe GmbH 215011 PWO

[0044] 14. Oktober 2025

[0045] 6 / 25

[0046] In the drawings:

[0047] Fig. 1 is a cross sectional detailed view of a pumping section of a blood pump;

[0048] Fig. 2 is a side view of a blood pump;

[0049] Fig. 3 is an enlarged view of detail Z shown in Fig. 2;

[0050] Fig. 4 is an enlarged view of detail Y shown in Fig. 2;

[0051] Fig. 5 is a cross section through a second portion of a cable of the blood pump shown in Fig.

[0052] 2;

[0053] Fig. 6 is a cross section through a first portion of the cable of the blood pump shown in Fig. 2 according to a first embodiment;

[0054] Fig. 7 is a cross section through a first portion of the cable of the blood pump shown in Fig. 2 according to a second embodiment; and

[0055] Fig. 8 is a cross section through a fist portion of the cable of the blood pump shown in Fig. 2 according to a third embodiment.

[0056] DETAILED DESCRIPTION

[0057] Fig. 1 depicts a cross sectional view of a pumping section 12 of a blood pump 10. The pumping section 12 comprises a pump housing 14 with a blood flow inlet 16 and at least one blood flow outlet 18. In this exemplary embodiment, the blood pump 10 is an intravascular pump, also called catheter pump, and the pumping section 12 is placed in a human body. In particular, the pumping section is deployed into a patient’s blood vessel by means of a catheter 20. In this exemplary embodiment, the blood pump is a left ventricle assist device, meaning that the pumping section 12 is at least partially to be placed within the left ventricle of the heart of the human body.

[0058] In this exemplary embodiment, the catheter is provided in the form of a cable 20. The blood flow inlet 16 is disposed at an end of a flexible cannula 22 which may be placed through a heart valve, such as the aortic valve, during usage of the blood pump 10. The at least one blood flow outlet 18 is disposed in a side surface of the pump housing 14 and may be placed in a blood vessel, such as the aorta. The blood pump 10 is electrically connected with a plurality of electric wires 24.1 extending through the cable 20 for supplying the blood pump 10 with electric power in order to drive the blood pump 10 by means of a drive unit 26. It has to be noted that the plurality of electric wires 24.1 are only schematically shown in Fig. 1 . In addition, a purge lumen 62 is provided within the cable 20 to supply a New PCT Application

[0059] Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0060] 7 / 25 purge solution to the pumping section 12. A more detailed description of the cable 20 will be provided below.

[0061] If the blood pump 10 is intended to be used in long term applications i.e., in situations in which the blood pump 10 is placed into the patient’s body for a longer period of time (e.g., several weeks or even months), electric power is preferably supplied by means of a battery. This allows a patient to be mobile because the patient is not connected to a base station. The battery can be carried by the patient and may supply electric energy to the blood pump 10 in a conventional manner.

[0062] A pump element 28 in form of an impeller is provided for conveying blood along a blood flow passage 30 connecting the blood flow inlet 16 and the blood flow outlet 18. As depicted in Fig. 1 , the impeller 28 is disposed within the pump housing 14 and is rotatable about an axis of rotation AR via a first bearing 32 and a second bearing 33. The axis of rotation AR is preferably the longitudinal axis of the impeller 28. Both bearings 32, 33 are contact-type bearings in this exemplary embodiment.

[0063] The drive unit 26 comprises a plurality of posts 34, such as six posts 34, only two of which are visible in the cross-sectional view of Fig. 1 . The posts 34 are disposed in parallel to the axis of rotation AR, more specifically, a longitudinal axis of each of the posts 34 is parallel to the axis of rotation AR. Coil windings 36 are disposed about the posts 34. The coil windings 36 are sequentially controlled by a control to create a rotating magnetic field. The impeller 28 comprises at least one magnet 38. The magnet 38 is disposed at the end of the impeller 28 facing the drive unit 26. The magnet 28 is configured to interact with the rotating magnetic field so as to cause rotation of the impeller 28 about the axis of rotation AR.

[0064] Fig. 2 depicts a side view of the blood pump 10. It should first be noted that Fig. 2 is not drawn to scale. As shown in Fig. 2, the blood pump 10 comprises the cable 20. The cable 20 has a distal end 42 and a proximal end 44. The pumping section 12 is connected to the distal end 42 of the cable 20. A connector 40 is connected to the proximal end 44 of the cable 20. The connector 40 is configured to connect the cable 20 to further devices, like a battery or an external controller (not shown).

[0065] In this exemplary embodiment, the cable 20 comprises a first portion 46, a second portion 48, a third portion 50 and a fourth portion 52. The first portion 46 is a skin passage portion, the second portion 48 is an extracorporeal portion, the third portion 50 is an intracorporeal portion and the fourth portion 52 is an intravascular portion.

[0066] The extracorporeal portion 48 extends from the proximal end 44 of the cable 20 in a direction towards the distal end 42 of the cable 20. In other words, the connector 40 is connected to the extracorporeal portion 48 of the cable 20. When the pumping section 12 is placed within the human body, the extracorporeal portion 48 is entirely located outside of the human body. The extracorporeal portion 48 leads into the skin passage portion 46 via a first tapered portion 54. The skin passage portion 46 leads New PCT Application

[0067] Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0068] 8 / 25 into the intracorporeal portion 50 via a second tapered portion 56. The intracorporeal portion 50 leads into the intravascular portion 52 via a third tapered portion 58, see also Fig .4. The intravascular portion 52 then extends up to the distal end 42 of the cable 20. In this exemplary embodiment, the intravascular portion 52 has a higher stiffness than the intracorporeal portion 50. The intravascular portion 52 may have a higher stiffness than the skin passage portion 46 and the extracorporeal portion 48. The higher stiffness of the intravascular portion 52 allows for a facilitated placement of the pumping section 12 within the human body, as the intravascular portion 52 is thus stiff and rotatable enough to maneuver the pumping section 12 through a hemostasis valve (not shown) along the bends within the vessels and through the aortic valve into the left ventricle.

[0069] As shown in Figs. 2 and 3, the skin passage portion 46 has a first diameter DM1 which is smaller than the second diameter DM2 of the extracorporeal portion 48. Further, the first diameter DM1 of the skin passage portion 46 is also smaller than a third diameter DM3 of the intracorporeal portion 50. As such, the first tapered portion 54 tapers from the second diameter DM2 of the extracorporeal portion 48 to the first diameter DM1 of the skin passage portion 46. Accordingly, the second tapered portion 56 tapers from the search diameter DM3 of the intracorporeal portion 50 to the first diameter DM1 of the skin passage portion 46.

[0070] Furthermore, a barrier 60 is disposed about the skin passage portion 46. The barrier 60 comprises an anti-bacterial agent and is composed of a Dacron velour. In this exemplary embodiment, the barrier 60 is also disposed about the first tapered portion 54 and the second tapered portion 56. The barrier 60 may also extend a certain amount along the extracorporeal portion 48 in the intracorporeal portion 50.

[0071] When the pumping section 12 is placed within the human body, the exit site of the cable 20 in the skin of the patient is penetrated by the skin passage portion 46 and hence by the barrier 60. Thus, the risk of infections and inflammations is reduced due to the anti-bacterial characteristic of the barrier 60 and the smaller first diameter DM1 of the skin passage portion 46 compared to the larger second diameter DM2 of the extracorporeal portion 48 and the larger third diameter DM3 of the intravascular portion 50.

[0072] As one can further take from Figs. 2 to 4, the third diameter DM3 of the intracorporeal portion 50 maybe identical to the second diameter DM2 of the extracorporeal portion 48. The fourth diameter DM4 of the intravascular portion 52 is smaller than the third diameter DM3 of the intracorporeal portion 50. In particular, the fourth diameter DM4 of the intravascular portion 52 may be identical to the first diameter DM1 of the skin passage portion 46. Accordingly, the third tapered portion 58 tapers from the third diameter DM3 to the fourth diameter DM4.

[0073] Fig. 5 shows a cross section through the cable 20 in the extracorporeal portion 48 or the intracorporeal portion 50. As shown, the cable 20 comprises an outer sheathing or coating 68 which is made of a highly biocompatible material. The sheathing has a second wall thickness in the extracorporeal portion New PCT Application

[0074] Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0075] 9 / 25

[0076] 48 and third wall thickness in the intracorporeal portion 50. The cable 20 further comprises the purge lumen 62 and a lumen 64. The purge lumen 62 is configured to deliver a purge solution to the pumping section 12. The lumen 64 is configured to receive additional elements. In this exemplary embodiment, a first optical fiber 66.1 and a second optical fiber 66.2 disposed within the lumen 64. The first optical fiber 66.1 and the second optical fiber 66.2 are connected to respective optical sensors (not shown) provided at the pumping section 12. The signals delivered by the optical sensors are transmitted via the first optical fiber 66.1 and the second optical fiber 66.2 to a controller attached to the cable 20 via the connector 40 in a conventional manner. Of course, the lumen 64 may also be configured to receive only one optical fiber or more than two optical fibers. Furthermore, the cable 20 comprises a total of six second wires 24.2 in the extracorporeal portion 48 and a total of six third wires 24.3 in the intracorporeal portion 50, which are provided as electrical wires.

[0077] As mentioned above, the outer diameter of the cable 20 varies between the distal end 42 and the proximal end 44. In particular, the first diameter DM1 and the fourth diameter DM4 are smaller than the second diameter DM2 and the third diameter DM3. Different possibilities to reduce the diameter of the cable 20 at the skin passage portion 46 and the intravascular portion 52 are shown in Figs. 6 to 8.

[0078] Fig. 6 depicts a cross section through the cable 20 in the area of the skin passage portion 46 or the intravascular portion 52 according to a first exemplary embodiment. As shown, the cable 20 comprises a total of six first wires 24.1 in the skin passage portion 46 and a total of six fourth wires 24.4 in the intravascular portion 52, which are provided as electrical wires. The first electrical wires 24.1 and the fourth electrical wires 24.4 of this exemplary embodiment are identically configured as the second electrical wires 24.2 shown in Fig. 5. Here, the sheathing 68 comprises a first wall thickness in the skin passage portion 46 and a fourth wall thickness in the intravascular portion 52. The first wall thickness and the fourth wall thickness are reduced compared to the second wall thickness or the third wall thickness of the sheathing 68 in the extracorporeal portion 48 or the intracorporeal portion 50, as shown in Fig. 5. Due to the reduced wall thickness of the sheathing 68, the outer diameter of the cable 20 is reduced to the first diameter DM1 or the fourth diameter DM4 respectively.

[0079] Fig. 7 depicts a cross section through the cable 20 in the area of the skin passage portion 46 or the intravascular portion 52 according to a second exemplary embodiment. In this exemplary embodiment, the first wall thickness and the fourth wall thickness of the sheathing 68 are identical to the second wall thickness and the third wall thickness of the sheathing 68 of the cable 20 in the extracorporeal portion 48 and the intracorporeal portion 50 respectively. However, only three first electrical wires 24.1 or fourth electrical wires 24.4 respectively are provided.

[0080] Accordingly, at the transition between the extracorporeal portion 48 and the skin passage portion 50, always two of the six second electrical wires 24.2 merge into only one first electrical wire 24.1 . In particular, the merging of always two of the six second electrical wires 24.2 into only one first electrical New PCT Application

[0081] Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0082] 10 / 25 wire 24.1 may be provided in the first tapered portion 54. As only three first electrical wires 24.1 are provided in the skin passage portion 46, the overall outer diameter of the cable 20 is reduced to the first diameter DM1 .

[0083] At the transition between the skin passage portion 46 and the intracorporeal portion 50, the merging of the second electrical wires 24.2 down to three first electrical wires 24.1 is again dissolved and again a total of six third electrical wires 24.3 is provided, so that the outer diameter of the cable 20 is again increased to be the third diameter DM3. The dissolution of the merger of the electrical wires may be provided in the second tapered portion 56.

[0084] At the transition between the intracorporeal portion 50 and the intravascular portion 52, again always two of the six third electrical wires 24.3 merge into only one fourth electrical wire 24.4, as described above. Hence, the outer diameter of the cable 20 is again reduced from the third diameter DM3 to the fourth diameter DM4. The merging of always two of the six third electrical wires 24.3 into only one fourth electrical wire 24.4 may be provided in the third tapered portion 58.

[0085] Fig. 8 depicts a cross section through the cable 20 in the area of the skin passage portion 46 or the intravascular portion 52 according to a third exemplary embodiment. In this exemplary embodiment, the cable 20 comprises a total of six first electrical wires 24.1 in the skin passage portion 46 and a total of six fourth electrical wires 24.4 in the intravascular portion 52. The outer diameter of each of the first electrical wires 24.1 or fourth electrical wires 24.4 respectively is reduced compared to the outer diameter of the second electrical wires 24.2 provided in the extracorporeal portion 48 or the third electrical wires 24.3 provided in the intracorporeal portion 50. The reduction of the outer diameter of each of the first electrical wires 24.1 and the fourth electrical wires 24.4 allows to reduce the outer diameter of the cable 20 from the second diameter DM2 or the third diameter DM3 down to the first diameter DM1 or the fourth diameter DM4. Preferably, the change in the outer diameter of each of the electrical wires is provided in the first tapered portion 54, the second tapered portion 56 and the third tapered portion 58.

[0086] It has to be further noted that it is possible to achieve the smaller first diameter DM1 of the skin passage portion 46 differently from the smaller fourth diameter DM4 of the intravascular portion 52. For instance, the cable 20 in the skin passage portion 46 may be provided as shown in Fig. 7, while the cable 20 in the intravascular portion 52 is provided as shown in Fig. 8. In addition, the wall thickness of the sheathing 68 may also be reduced in the exemplary embodiment shown in Fig. 7 or Fig. 8. It is also possible to have a reduced number of first electrical wires 24.1 compared to the number of second electrical wires 24.2 and also to equally reduce the outer diameter of the first wires 24.1 . Furthermore, the sheathing 68 may also be configured to allow for the higher stiffness of the intravascular portion 52. New PCT Application

[0087] Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0088] 11 / 25

[0089] In addition, the number of electrical wires 24.1 , 24.2 is not limited to the shown number of six and three respectively. Rather, any numbers of electrical wires are possible. However, it is preferable that the number of first electrical wires 24.1 and second electrical wires 24.2 is a multiple of three, as the drive unit 26 is configured as a three-pole electrical motor, so that always an identical number of electrical wires 24.1 , 24.2 is provided for each of the three poles. Hence, the skin passage portion 46 may comprise a first number Ni of first electrical wires 24.1 and the extracorporeal portion 48 may comprise a second number N2 of second electrical wires 24.2, with N2 = 2 x N1 in case the number of the electrical wires is reduced in the skin passage portion 46. The intracorporeal portion 50 may comprise a third number N3 of second electrical wires 24.2. In this exemplary embodiment, the third number N3 is identical to the second number N2 of second electrical wires 24.2. The intravascular portion 52 may comprise a fourth number N4 of fourth electrical wires 24.4. The fourth number N4 may be identical to the first number N1 of first electrical wires 24.1 or may be different from the first number N1 of first electrical wires 24.1 , depending on how the diameter is reduced down to the fourth diameter DM4, as described above (i.e. , reducing the number of fourth electrical wires 24.4 or reducing the outer diameter of the fourth electrical wires 24.4 compared to the outer diameter of the third electrical wires 24.3).

[0090] In the exemplary embodiment of the cable 20 described above, the cable 20 may have an overall length between the distal end 42 and the proximal end 44 of e.g., approximately 1.300 mm. The skin passage portion 46 may have a length of approximately 80 mm and the extracorporeal portion may have a length of approximately 400 mm. The intracorporeal portion 50 may have a length of approximately 550 mm and the intravascular portion may have a length of approximately 270 mm. The first tapered portion 54, the second tapered portion 56 and the third tapered portion 58 may each have length of a few millimeters e.g., of 5 mm.

[0091] In the exemplary embodiment of the cable 20 described above, the first diameter DM1 may be 2.8 mm. The second diameter DM2 may be 5.3 mm. The third diameter may be 5.3 mm and the fourth diameter DM4 may be 2.8 mm. Based thereon, the overall cable resistance may be significantly reduced. The cable 20 as described above has an overall cable resistance of approximately 0,2 to 0,8 Q compared to a cable resistance of about 1 ,6 to 2,0 Q for a cable having a constant diameter of approximately 2.8 mm.

[0092] It has to be noted that in Figs. 5 to 8, the electrical wires 24.1 to 24.4 are only schematically shown. The electrical wires 24.1 to 24.4 may be provided as single conductors or also as twisted conductors. Furthermore, the electrical wires 24.1 to 24.4 may have a coating. The arrangement of the purge lumen 62, the lumen 64 and the electrical wires 24.1 to 24.4 is only exemplary and may be different. For instance, the electrical wires 24.1 to 24.4 do not have to be arranged in the diamond shape shown in Figs. 5, 6 and 8, but may also be distributed differently within the cable 20. New PCT Application

[0093] Abiomed Europe GmbH

[0094] 215011 PWO

[0095] 14. Oktober 2025

[0096] 12 / 25

[0097] EXEMPLARY IMPLEMENTATIONS

[0098] As already described, the technology described herein may be implemented in various ways. In that regard, the foregoing disclosure is intended to include, but not be limited to, the systems, methods, and combinations and subcombinations thereof that are set forth in the following exemplary implementations. Preferred embodiments are described in the following paragraphs:

[0099] A1 Blood pump comprising: a pumping section configured to be placed in a human body, a cable and a connector; wherein the cable comprises a distal end, a proximal end, a first portion and a second portion; wherein the distal end of the cable is connected to the pumping section and wherein the proximal end of the cable is connected to the connector; wherein the first portion has a first diameter DM1 and the second portion 48 has a second diameter DM2.

[0100] A2 Blood pump according to paragraph A1 , wherein the first diameter is different from the second diameter

[0101] A3 Blood pump according to paragraph A1 or A2, wherein the first diameter is smaller than the second diameter

[0102] A4 Blood pump according to any one of the preceding paragraphs A1 to A3, wherein the first portion is a skin passage portion.

[0103] A5 Blood pump according to any one of the preceding paragraphs A1 to A4, wherein the second portion is an extracorporeal portion.

[0104] A6 Blood pump according to any one of the preceding paragraphs A1 to A5, wherein first portion constitutes between 1% and 50% of the cable.

[0105] A7 Blood pump according to paragraph A6, wherein the first portion constitutes between 2% and 30% of the cable.

[0106] A8 Blood pump according to paragraph A7, wherein the first portion constitutes between 3% and 30% of the cable.

[0107] A9 Blood pump according to paragraph A8, wherein the first portion constitutes between 4% and 10% of the cable.

[0108] A10 Blood pump according to any one of the preceding paragraphs A1 to A9, wherein first diameter is between 30% and 80% of the second diameter. New PCT Application

[0109] Abiomed Europe GmbH

[0110] 215011 PWO

[0111] 14. Oktober 2025

[0112] 13 / 25

[0113] A11 Blood pump according to paragraph A10, wherein the first diameter is between 40% and 70% of the second diameter.

[0114] A12 Blood pump according to paragraph A11 , wherein the first diameter is between 45% and 60% of the second diameter.

[0115] A13 Blood pump according to paragraph A12, wherein the first diameter is between 45% and 55% of the second diameter.

[0116] A14 Blood pump according to any one of the preceding paragraphs A1 to A13, wherein first portion is disposed between the distal end of the cable and the second portion.

[0117] A15 Blood pump according to any one of the preceding paragraphs A1 to A14, wherein the second portion is disposed between the proximal end of the cable and the first portion.

[0118] A16 Blood pump according to any one of the preceding paragraphs A1 to A15, wherein the cable comprises a first tapered portion.

[0119] A17 Blood pump according to paragraph A16, wherein the first tapered portion is disposed between the first portion and the second portion.

[0120] A18 Blood pump according to paragraph A16 or A17, wherein the first tapered portion tapers from the second diameter to the first diameter.

[0121] A19 Blood pump according to any one of the preceding paragraphs A1 to A18, wherein the cable comprises a third portion disposed between the first portion and the distal end of the cable.

[0122] A20 Blood pump according to paragraph A19, wherein the third portion has a third diameter.

[0123] A21 Blood pump according to paragraph A20, wherein the third diameter is larger than the first diameter.

[0124] A22 Blood pump according to paragraph A21 , wherein the third diameter is identical to the second diameter.

[0125] A23 Blood pump according to any one of the preceding paragraphs A19 to A22, wherein the third portion is an intracorporeal portion.

[0126] A24 Blood pump according to any one of the preceding paragraphs A1 to A23, wherein the cable comprises a second tapered portion. New PCT Application

[0127] Abiomed Europe GmbH

[0128] 215011 PWO

[0129] 14. Oktober 2025

[0130] 14 / 25

[0131] A25 Blood pump according to paragraph A24, wherein the second tapered portion is disposed between the first portion and the third portion.

[0132] A26 Blood pump according to paragraph A25, wherein the second tapered portion tapers from the third diameter to the first diameter.

[0133] A27 Blood pump according to any one of the preceding paragraphs A1 to A26, wherein the cable comprises a fourth portion disposed between the third portion and the distal end of the cable.

[0134] A28 Blood pump according to paragraph A27, wherein the fourth portion is an intravascular portion.

[0135] A29 Blood pump according to paragraph A27 or A28, wherein the fourth portion has a fourth diameter.

[0136] A30 Blood pump according to paragraph A29, wherein the fourth diameter is smaller than the second diameter.

[0137] A31 Blood pump according to paragraph A29 or A30, wherein the fourth diameter is smaller than the third diameter.

[0138] A32 Blood pump according to any one of the preceding paragraphs A29 to A31 , wherein the fourth diameter is identical to the first diameter.

[0139] A33 Blood pump according to any one of the preceding paragraphs A1 to A32, wherein the cable comprises a third tapered portion.

[0140] A34 Blood pump according to paragraph A33, wherein the third tapered portion is disposed between the fourth portion and the third portion.

[0141] A35 Blood pump according to paragraph A33 or A34, wherein the third tapered portion tapers from the third diameter to the fourth diameter.

[0142] A36 Blood pump according to any one of the preceding paragraphs A27 to A35, wherein the fourth portion has a higher stiffness than the first portion.

[0143] A37 Blood pump according to any one of the preceding paragraphs A27 to A36, wherein the fourth portion has a higher stiffness than the second portion.

[0144] A38 Blood pump according to any one of the preceding paragraphs A27 to A37, wherein the fourth portion has a higher stiffness than the third portion. New PCT Application

[0145] Abiomed Europe GmbH

[0146] 215011 PWO

[0147] 14. Oktober 2025

[0148] 15 / 25

[0149] A39 Blood pump according to any one of the preceding paragraphs A1 to A38, wherein the blood pump further comprises a barrier.

[0150] A40 Blood pump according to paragraph A39, wherein the barrier is disposed about the first portion.

[0151] A41 Blood pump according to paragraph A40, wherein the barrier is disposed about the first tapered portion.

[0152] A42 Blood pump according to paragraph A40 or A41 , wherein the barrier is disposed about the second tapered portion.

[0153] A43 Blood pump according to any one of the preceding paragraphs A39 to A42, wherein the barrier comprises an anti-bacterial agent.

[0154] A44 Blood pump according to any one of the preceding paragraphs A39 to A43, wherein the barrier is at least partially composed of a Dacron velour.

[0155] A45 Blood pump according to any one of the preceding paragraphs A1 to A44, wherein the first portion comprises at least one first wire.

[0156] A46 Blood pump according to any one of the preceding paragraphs A1 to A45, wherein the second portion comprises at least one second wire.

[0157] A47 Blood pump according to paragraph A46 or A47, wherein the at least one first wire has a different diameter than the at least one second wire.

[0158] A48 Blood pump according to paragraph A47, wherein the diameter of the first wire is smaller than the diameter of the second wire.

[0159] A49 Blood pump according to any one of the preceding paragraphs A1 to A48, wherein the first portion comprises Ni first wires and the second portion comprises N2 second wires.

[0160] A50 Blood pump according to paragraph A49, wherein N1 is equal or larger than 1 and N2 is larger than N1 and larger or equal than 2.

[0161] A51 Blood pump according to paragraph A49 or A50, wherein N1 and N2 are a multiple of 3.

[0162] A52 Blood pump according to any one of the preceding paragraphs A1 to A51 , wherein the third portion comprises at least one third wire. New PCT Application

[0163] Abiomed Europe GmbH

[0164] 215011 PWO

[0165] 14. Oktober 2025

[0166] 16 / 25

[0167] A53 Blood pump according to paragraph A52, wherein the at least one third wire has a larger diameter than the at least one first wire.

[0168] A54 Blood pump according to paragraph A52 or A53, wherein the diameter of the at least one third wire is identical to the diameter of the at least one second wire.

[0169] A55 Blood pump according to any one of the preceding paragraphs A1 to A54, wherein the third portion comprises N3 third wires

[0170] A56 Blood pump according to paragraph A55, wherein N3 is larger than N1.

[0171] A57 Blood pump according to paragraph A55 or A56, wherein N3 is equal or larger than 2.

[0172] A58 Blood pump according to any one of the preceding paragraphs A55 to A57, wherein N3 is multiple of 3.

[0173] A59 Blood pump according to any one of the preceding paragraphs A55 to A58, wherein N3 is identical to N2.

[0174] A60 Blood pump according to any one of the preceding paragraphs A1 to A59, wherein the fourth portion comprises at least one fourth wire.

[0175] A61 Blood pump according to paragraph A60, wherein the at least one fourth wire has a smaller diameter than the at least one second wire.

[0176] A62 Blood pump according to any one of the preceding paragraphs A1 to A61 , wherein the fourth portion comprises N4 fourth wires.

[0177] A63 Blood pump according to paragraph A62, wherein N4 is equal or larger than 1 .

[0178] A64 Blood pump according to paragraph A62 or A63, wherein N4 is identical to N1.

[0179] A65 Blood pump according to any one of the preceding paragraphs A62 to A64, wherein N4 is a multiple of 3.

[0180] A66 Blood pump according to any one of the preceding paragraphs A45 to A65, wherein the at least one first wire is a first electrical wire.

[0181] A67 Blood pump according to any one of the preceding paragraphs A45 to A66, wherein the at least one second wire is a second electrical wire.

[0182] A68 Blood pump according to any one of the preceding paragraphs A45 to A67, wherein the at least one third wire is a third electrical wire. New PCT Application

[0183] Abiomed Europe GmbH

[0184] 215011 PWO

[0185] 14. Oktober 2025

[0186] 17 / 25

[0187] A69 Blood pump according to any one of the preceding paragraphs A45 to A68, wherein the at least one fourth wire is a fourth electrical wire.

[0188] A70 Blood pump according to any one of the preceding paragraphs A1 to A69, wherein the cable comprises at least one optical fiber.

[0189] A71 Blood pump according to paragraph A70, wherein the cable comprises two optical fibers.

[0190] A72 Blood pump according to any one of the preceding paragraphs A1 to A71 , wherein the cable comprises at least one lumen.

[0191] A73 Blood pump according to paragraph A72, wherein the at least one optical fiber is disposed in the lumen.

[0192] A74 Blood pump according to any one of the preceding paragraphs A1 to A73, wherein the cable comprises at least one purge lumen configured to deliver a purge solution to the pumping section.

[0193] A75 Blood pump according to any one of the preceding paragraphs A1 to A74, wherein the cable comprises a sheathing or coating as a radially outermost layer.

[0194] A76 Blood pump according to paragraph A75, wherein the sheathing or coating is of a highly biocompatible material.

[0195] A77 Blood pump according to paragraph A75 or A76, wherein the sheathing or coating has a first wall thickness in the first portion and a second wall thickness in the second portion.

[0196] A78 Blood pump according to paragraph A77, wherein the first wall thickness is smaller than the second wall thickness.

[0197] A79 Blood pump according to any one of the preceding paragraphs A75 to A78, wherein the sheathing or coating may have a third wall thickness in the third portion and fourth wall thickness in the fourth portion.

[0198] A80 Blood pump according to paragraph A79, wherein the third wall thickness is larger than the first wall thickness.

[0199] A81 Blood pump according to paragraph A79 or A80, wherein the third wall thickness is larger than the fourth wall thickness.

[0200] A82 Blood pump according to any one of the preceding paragraphs A79 to A81 , wherein the third wall thickness is equal to the second wall thickness. New PCT Application

[0201] Abiomed Europe GmbH

[0202] 215011 PWO

[0203] 14. Oktober 2025

[0204] 18 / 25

[0205] A83 Blood pump according to any one of the preceding paragraphs A79 to A82, wherein the fourth wall thickness is smaller than the second wall thickness.

[0206] A84 Blood pump according to any one of the preceding paragraphs A1 to A83, wherein the first diameter is between 2 mm and 3 mm.

[0207] A85 Blood pump according to any one of the preceding paragraphs A1 to A84, wherein the first diameter is smaller than 3 mm.

[0208] A86 Blood pump according to any one of the preceding paragraphs A1 to A85, wherein the first diameter is between 2.5 mm and 2.9 mm.

[0209] A87 Blood pump according to any one of the preceding paragraphs A1 to A88, wherein the first diameter is 2.8 mm.

[0210] A88 Blood pump according to any one of the preceding paragraphs A1 to A87, wherein the second diameter is between 3 mm and 6 mm.

[0211] A89 Blood pump according to any one of the preceding paragraphs A1 to A88, wherein the second diameter is larger than 3 mm.

[0212] A90 Blood pump according to any one of the preceding paragraphs A1 to A89, wherein the second diameter is between 5.0 mm and 5.5 mm.

[0213] A91 Blood pump according to any one of the preceding paragraphs A1 to A90, wherein the second diameter is 5.3 mm.

[0214] A92 Blood pump according to any one of the preceding paragraphs A1 to A91 , wherein the third diameter is between 3 mm and 6 mm.

[0215] A93 Blood pump according to any one of the preceding paragraphs A1 to A92, wherein the third diameter is larger than 3 mm.

[0216] A94 Blood pump according to any one of the preceding paragraphs A1 to A93, wherein the third diameter is between 5.0 mm and 5.5 mm.

[0217] A95 Blood pump according to any one of the preceding paragraphs A1 to A94, wherein the third diameter is 5.3 mm.

[0218] A96 Blood pump according to any one of the preceding paragraphs A1 to A95, wherein the fourth diameter is between 2 mm and 3 mm. New PCT Application

[0219] Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0220] 19 / 25

[0221] A97 Blood pump according to any one of the preceding paragraphs A1 to A96, wherein the fourth diameter is smaller than 3 mm.

[0222] A98 Blood pump according to any one of the preceding paragraphs A1 to A97, wherein the fourth diameter is between 2.5 mm and 2.9 mm.

[0223] A99 Blood pump according to any one of the preceding paragraphs A1 to A98, wherein the fourth diameter is 2.8 mm.

[0224] A100 Blood pump according to any one of the preceding paragraphs A1 to A99, wherein the cable is a catheter.

[0225] As utilized herein, the terms “approximately”, “about”, “substantially” and similar terms are intended to have a broad meaning in harmony with the common and accepted usage by those of ordinary skill in the art to which the subject matter of this disclosure pertains. It should be understood by those of skill in the art who review this disclosure that these terms are intended to allow a description of certain features described without restricting the scope of these features to the precise numerical ranges provided. Accordingly, these terms should be interpreted as indicating that insubstantial or inconsequential modifications or alterations of the subject matter described and are considered to be within the scope of the disclosure. The terms „at least partially” or “partially” as used herein mean both partial and entirely or complete respectively. Furthermore, terms like “first” or “second” do not imply a specific order, but are only intended to allow for linguistic differentiation between the elements.

[0226] New PCT Application Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0227] 20 / 25

[0228] List of reference signs

[0229] 10 blood pump

[0230] 12 pumping section

[0231] 14 pump housing

[0232] 16 blood flow inlet

[0233] 18 blood flow outlet

[0234] 20 cable

[0235] 22 cannula

[0236] 24.1 to 24.4 electrical wire

[0237] 26 drive unit

[0238] 28 impeller

[0239] 30 blood flow passage

[0240] 32 first bearing

[0241] 33 second bearing

[0242] 34 post

[0243] 36 coil winding

[0244] 38 magnet

[0245] 40 connector

[0246] 42 distal end of cable

[0247] 44 proximal end of cable

[0248] 46 first portion / skin passage portion

[0249] 48 second portion / extracorporeal portion

[0250] 50 third portion / intracorporeal portion

[0251] 52 fourth portion / intravascular portion

[0252] 54 first tapered portion

[0253] 56 second tapered portion

[0254] 58 third tapered portion

[0255] 60 barrier

[0256] 62 purge lumen

[0257] 64 lumen

[0258] 66.1 , 66.2 optical fiber

[0259] 68 sheathing

[0260] AR axis of rotation

[0261] DM1 first diameter

[0262] DM2 second diameter New PCT Application Abiomed Europe GmbH 215011 PWO 14. Oktober 2025

[0263] 21 / 25

[0264] DM3 third diameter

[0265] DM4 fourth diameter

Claims

New PCT ApplicationAbiomed Europe GmbH215011 PWO14. Oktober 202522 / 25CLAIMS1. Blood pump (10) comprising: a pumping section (12) configured to be placed in a human body, a cable (20) and a connector (40); wherein the cable (20) comprises a distal end (42), a proximal end (44), a first portion (46) and a second portion (48); wherein the distal end (42) of the cable (20) is connected to the pumping section (12) and wherein the proximal end (44) of the cable (20) is connected to the connector (40); wherein the first portion (46) has a first diameter (DM1) and the second portion (48) has a second diameter (DM2), wherein the first diameter (DM1) is different from the second diameter (DM2), wherein the first diameter (DM1) is preferably smaller than the second diameter (DM2), wherein the first portion (46) preferably is a skin passage portion and wherein the second portion (48) preferably is an extracorporeal portion.

2. Blood pump (10) according to claim 1 , wherein the first portion (46) constitutes between 1% and 50% of the cable (20), preferably between 2% and 30% of the cable (20), even more preferably between 3% and 20% of the cable (20) and most preferably between 4% and 10% of the cable (20), and / or wherein the first diameter (DM1) is between 30% and 80% of the second diameter (DM2), preferably between 40% and 70% of the second diameter (DM2), even more preferably between 45% and 60% of the second diameter (DM2) and most preferably between 45% and 55% of the second diameter (DM2).

3. Blood pump (10) according to claim 1 or 2, wherein the first portion (46) is disposed between the distal end (42) of the cable (20) and the second portion (48), and wherein the second portion (48) is disposed between the proximal end of the cable (20) and the first portion (46).

4. Blood pump (10) according to any one of the preceding claims, wherein the cable (20) comprises a first tapered portion (54) disposed between the first portion (46) and the second portion (48), wherein the first tapered portion (54) tapers from the second diameter (DM2) to the first diameter (DM1).New PCT ApplicationAbiomed Europe GmbH215011 PWO14. Oktober 202523 / 255. Blood pump (10) according to any one of the preceding claims, wherein the cable (20) comprises a third portion (50) disposed between the first portion (46) and the distal end (42) of the cable (20), wherein the third portion (50) has a third diameter (DM3), wherein the third diameter (DM3) is larger than the first diameter (DM1), and wherein the third diameter (DM3) is preferably identical to the second diameter (DM2), wherein the third portion (50) preferably is an intracorporeal portion.

6. Blood pump (10) according to claim 5, wherein the cable (20) comprises a second tapered portion (56) disposed between the first portion (46) and the third portion (50), wherein the second tapered portion (56) tapers from the third diameter (DM3) to the first diameter (DM3).

7. Blood pump (10) according to claim 5 or 6, wherein the cable (20) comprises a fourth portion (52) disposed between the third portion (50) and the distal end (42) of the cable (20), wherein the fourth portion (52) is preferably an intravascular portion.

8. Blood pump (10) according to claim 7, wherein the fourth portion (52) has a fourth diameter (DM4), wherein the fourth diameter (DM4) is smaller than the second diameter (DM2).

9. Blood pump (10) according to claim 8, wherein the cable (20) comprises a third tapered portion (58) disposed between the fourth portion (52) and the third portion (50), wherein the third tapered portion (58) tapers from the third diameter (DM3) to the fourth diameter (DM4).

10. Blood pump (10) according to any one of the preceding claims 7 to 9, wherein the fourth portion (52) has a higher stiffness than the first portion (46) and / or than the second portion (48) and / or than the third portion (50).

11. Blood pump (10) according to any one of the preceding claims, wherein a barrier (60) comprising anti-bacterial agent is disposed about the first portion (46), wherein the barrier (60) is preferably at least partially composed of Dacron velour.

12. Blood pump (60) according to any one of the preceding claims, wherein the first portion (46) comprises at least one first wire (24.1) and the second portion(48) comprises at least one second wire (24.2), wherein the at least one first wire (24.1) has aNew PCT ApplicationAbiomed Europe GmbH 215011 PWO14. Oktober 202524 / 25 different diameter than the at least one second wire (24.2), wherein the diameter of the first wire (24.1) is preferably smaller than the diameter of the second wire (24.2).

13. Blood pump (10) according to claim 12, wherein the first portion (46) comprises Ni first wires (24.1) and the second portion (48) comprises N2 second wires (24.2), wherein N1 > 1 and wherein N2 s 2 and wherein N2 > N1.

14. Blood pump (10) according to any one of the preceding claims, wherein the cable (20) comprises at least one optical fiber (66.1 , 66.2) and / or at least one purge lumen (62).

15. Blood pump (10) according to any one of the preceding claims, wherein the first diameter (DM1) is between 2 mm and 3 mm, wherein the first diameter (DM1) is preferably smaller than 3 mm, wherein the first diameter (DM2) is preferably between 2.5 mm and 2.9 mm, wherein the first diameter (DM1) is preferably 2.8 mm, and / or wherein the second diameter (DM2) is between 3 mm and 6 mm, wherein the second diameter (DM2) is preferably larger than 3 mm, wherein the second diameter (DM2) is preferably between 5.0 mm and 5.5 mm, wherein the second diameter (DM2) is preferably 5.3 mm, and / or wherein the third diameter (DM3) is between 3 mm and 6 mm, wherein the third diameter (DM3) is preferably larger than 3 mm, wherein the third diameter (DM3) is preferably between 5.0 mm and 5.5 mm, wherein the third diameter (DM3) is preferably 5.3 mm, and / or wherein the fourth diameter (DM4) is between 2 mm and 3 mm, wherein the fourth diameter (DM4) is preferably smaller than 3 mm, wherein the fourth diameter (DM4) is preferably between 2.5 mm and 2.9 mm, wherein the fourth diameter (DM4) is preferably 2.8 mm.

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