A device for the collection of blood and a method for using the same

Abstract

According to some embodiments, there is provided herein a device for drawing blood from the ear of an animal comprising a housing containing a blade for making an incision in the ear; at least one fastening mechanism designed to secure the device onto the ear of the animal; and an absorbent pad to configured collect blood from the incision.

Description

[0001] A DEVICE FOR THE COLLECTION OF BLOOD AND A METHOD FOR USING THE SAME FIELD OF THE INVENTION

[0002] The present application is in the field of devices and techniques for drawing of blood, and specifically for drawing of blood from animals.

[0003] BACKGROUND OF THE INVENTION

[0004] In the field of veterinary medicine, it is often necessary to collect blood samples from animals for diagnostic and health monitoring purposes. However, when it comes to animals, conventional methods for blood collection can be difficult to perform, causing discomfort and stress for the animal, which may lead to resistance during the procedure. This can complicate the process and require repeated attempts, increasing the risk of injury and further stress to the animal.

[0005] Additionally, current methods for collecting blood may not adequately address the need for precision, hygiene, and efficiency. Devices used in veterinary blood collection can lack appropriate mechanisms for controlling the depth of incisions, leading to inconsistent results, excessive bleeding, or unnecessary pain. Moreover, loud noises generated during the operation of mechanical devices can cause additional distress, making animals more anxious or uncooperative during subsequent procedures.

[0006] CA2666207 teaches means for sampling animal blood.

[0007] CN111603180 discusses convenient blood detection system

[0008] KR20110004845 teaches device, system and method for modular analyte monitoring

[0009] SUMMARY OF THE INVENTION

[0010] According to some embodiments, there is provided herein a device for drawing blood from the ear of an animal comprising: a rotating housing that contains a blade for making an incision in the ear; a fastening mechanism designed to secure the device onto the ear of the animal; an absorbent pad positioned directly beneath the blade, configured to collect blood from the incision immediately following the cut. It is to be understood that the term “configured to collect blood” may relate to any structural, material, or spatial adaptation that enables the absorbent pad to efficiently receive, retain, or direct the flow of blood following the incision. This includes, but is not limited to, the use of capillary-action materials, hydrophilic coatings, micro-porous substrates, directional flow channels, or any design that ensures rapid and effective sample uptake immediately post-cut.

[0011] According to some embodiments, the device may further comprise an adjustment mechanism, e.g., configured to control the depth of the blade.

[0012] According to some embodiments, blade may be adjustable, allowing the depth of the incision to be tailored to the size and thickness of the animal's ear.

[0013] According to some embodiments, the device may further include a silencer integrated into the rotating housing to reduce noise during operation.

[0014] According to some embodiments, the silencer may be made from a material selected from the group consisting of silicone, rubber, foam, and composite materials.

[0015] According to some embodiments, the device of the present invention may further comprise a capsule positioned in the path of said blade, which releases one or more medicinal agents upon being cut by the blade.

[0016] According to some embodiments, wherein the medicinal agents may include at least one of a pain reliever, a local anesthetic, a coagulant and an antiseptic.

[0017] According to some embodiments, the device may further include a heating element configured to warm the ear prior to or during the incision process.

[0018] According to some embodiments, the heating element may operate through electric resistance heating or chemical activation.

[0019] According to some embodiments, the absorbent pad may be detachable and disposable. According to some embodiments, the device may comprise an analysis strip connected to the absorbent pad for conducting one or more blood analyses directly from the collected blood.

[0020] According to some embodiments, the fastening mechanism may be selected from the group including at least one of adjustable straps, a magnetic fastening system, a clip, a suction-based system, hook and loop fasteners, adhesive pads, custom molded fittings, or a slide lock mechanism. According to some embodiments, the fastening mechanism is preferably a clip adjustable to accommodate varying thicknesses and sensitivities of animal ears.

[0021] BRIEF DESCRIPTION OF THE FIGURES

[0022] Fig. l is a cross-section side view of the device of the present invention, in accordance with some demonstrative embodiments.

[0023] Fig. 2 is a cross-section side view of the device of the present invention, in accordance with some demonstrative embodiments.

[0024] Fig. 3 is a cross-section side view of the device of the present invention, in accordance with some demonstrative embodiments.

[0025] Fig. 4 is a side view of the device of the present invention, in accordance with some demonstrative embodiments.

[0026] Fig. 5 is a view of an exemplary strip 110, in accordance with some demonstrative embodiments.

[0027] Fig. 6 is a cross section of device 100, in accordance with some demonstrative embodiments

[0028] DETAILED DESCRIPTION OF THE INVENTION

[0029] According to some demonstrative embodiments, there is provided herein a multifunctional device designed for drawing blood from the ear of an animal, preferably a dog or a cat, enhancing the overall procedure through various innovative components that can be combined in numerous configurations to optimize performance and comfort.

[0030] In some exemplary embodiments, the term "animal" as used herein refers to mammals with ears, particularly primates, even-toed ungulates, and Carnivora.

[0031] Preferably, these animals are pets, with a focus on dogs and cats.

[0032] In certain embodiments, the device is specifically engineered to meet the distinct anatomical needs of animals, and preferably, of dogs and / or cats. Both species possess unique ear structures within the animal kingdom, characterized by a hairless inner portion (pinna) with accessible blood vessels. Consequently, the device is designed to enable precise, minimally invasive, and nearly painless incisions into this inner part of the ear. According to some embodiments, the unique configuration of the blade and actuation mechanism in the present device allows for the extraction of a minimum blood volume suitable for diagnostic tests, for example, as appearing in table 1 below:

[0033]

[0034] Table 1 - Optional Blood Tests for Use with the Device of the Present Invention

[0035] According to some embodiments, the method of incision and fluid handling is specifically designed to extract at least 50 microliters (pL) of blood per activation, with preferred embodiments consistently providing 150 pL or more. These volumes are sufficient to perform a wide range of veterinary diagnostic tests, including but not limited to: fertility monitoring (e.g., progesterone levels for ovulation and pregnancy), antibody titer testing (e.g., for rabies, distemper, leptospirosis, parvovirus, FIV, FeLV, and others), zoonotic infection screening (e.g., toxoplasmosis or brucellosis), biochemical panels (e.g., liver and kidney function tests), and parasite detection and follow-up (e.g., heartworm, Ehrlichia, Spirocerca lupi). According to some embodiments, the extracted volume also supports nutritional assessments through the measurement of trace elements and microelements in the blood. Such diagnostic procedures typically require blood volumes that exceed the capacity of conventional microfluidic sampling devices, thus emphasizing the advantage of the present invention in both clinical and home-use veterinary settings.

[0036] Additionally, the device is tailored to cause minimal or no pain, avoiding trauma, which is crucial as dogs and cats are sensitive to discomfort and noise. Given that blood samples may need to be drawn multiple times, it is vital to minimize trauma to ensure ease of future use.

[0037] The unique design, detailed further below, allows for easy attachment to the animal's ear and operates quietly to reduce the risk of stress or resistance from the animal, particularly dogs and cats.

[0038] According to some embodiments, the device may integrate an adjustable blade which is pivotal for making a controlled incision in the animal's ear. The adjustability of the blade allows for precise depth control, making the device versatile and safe for different breeds and ear sizes. According to some embodiments, the adjustment mechanism may aid in regulating the blade's position, ensuring accuracy and consistency in the depth of the incision.

[0039] According to some embodiments, the device comprises a blade adjustment mechanism configured to allow precise control over the depth of the incision made in the animal’s ear. This mechanism is particularly advantageous in accommodating the natural variability in ear thickness and tissue structure among different animals or breeds, thereby ensuring effective blood collection while minimizing the risk of injury or excessive penetration.

[0040] In some embodiments, the blade is adjustable without requiring replacement or exchange, providing a simple and user-friendly solution for both professional and nonprofessional users. The adjustment may be performed prior to actuation of the device and may include incremental or continuous control depending on the design.

[0041] The blade adjustment mechanism may include, for example:

[0042] A threaded dial mechanism that translates rotational input into linear movement of the blade; A sliding track or slot with discrete locking notches for preset depth positions; or a ratchet mechanism that allows stepwise control of blade extension with tactile or audible feedback.

[0043] According to some embodiments, these mechanisms may be integrated within the rotating housing or externally accessible to the user, and may include depth indicators, tactile detents, or visual markers to assist in setting the desired incision depth prior to use. In preferred embodiments, the mechanism is designed to prevent over-extension of the blade beyond a safe maximum threshold, further enhancing the safety of the device.

[0044] By incorporating such an adjustment feature, the device may ensure that a sufficient amount of blood is collected for the intended diagnostic procedures, while maintaining animal welfare and user confidence.

[0045] According to some embodiments, the device may include a housing component which encases and secures the blade and adjustment mechanism, safeguarding against accidental cuts and ensuring the blade's proper alignment during operation.

[0046] According to some demonstrative embodiments, the device is uniquely positioned on the ear of the animal, and is securely fastened to the ear to ensure an effective withdrawal of blood. According to some embodiments, the device may be fastened via one or more ways, selected from the following group:

[0047] Adjustable Straps: Using straps made from soft, flexible materials like silicone or fabric can help in securing the device more comfortably around the ear. These straps can be adjustable to fit different ear sizes and shapes securely without causing undue pressure or discomfort.

[0048] Magnetic Fastening System: Employing magnets can offer a non -invasive and quick method to attach and detach the device. Magnets can be embedded within the device and a corresponding lightweight, non-obtrusive counterpiece can be placed on the opposite side of the ear.

[0049] Hook and Loop Fasteners: Commonly known by the brand name Velcro, hook and loop fasteners can provide an easy and adjustable method of securing the device. These can be tailored to wrap around the ear comfortably and can be quickly adjusted as needed.

[0050] Adhesive Pads: Using medical-grade adhesives on parts of the device that contact the ear can ensure a secure fit without the need for physical clamps. These adhesives would be designed to be gentle on the skin and easy to remove without residue or discomfort.

[0051] Slide Lock Mechanism: A slide lock can provide a secure fastening method that can be easily adjusted and locked into place. This mechanism would allow for quick adjustments to ensure a snug fit without exerting excessive pressure. A clip mechanism that secures the device onto the ear of the animal, maintaining stability and the correct positioning throughout the procedure. This clip can be equipped with adjustable tension settings to accommodate the thickness and sensitivity of different animals’ ears, ensuring comfort and safety.

[0052] According to some embodiments, beneath the blade, an absorbent pad is strategically positioned to efficiently capture and collect the blood drawn during the procedure. This pad can be designed as detachable and disposable, promoting hygiene and ease of use. Connected to this pad, an optional strip may be included for conducting on-the-spot blood analyses, such as glucose monitoring or red blood cell counts, adding a layer of functionality by providing immediate health metrics.

[0053] According to some embodiments, the present invention provides a diagnostic strip that is either connected to or integrated within the blood collection device. The strip may be configured to receive the blood collected from the animal's ear and facilitate diagnostic analysis, for example, such as immunological or biochemical testing, either visually or instrumentally.

[0054] In order to improve usability, especially in non-clinical or home environments, the strip may further comprise a blood volume indicator configured to provide immediate visual feedback confirming whether a sufficient quantity of blood has been delivered to the test area. According to some embodiments, this feature may be particularly important in diagnostic contexts where accurate results depend on a minimum threshold volume, such as 50 microliters (pL), 100 pL, or more. In the absence of such feedback, an insufficient sample may lead to false negative results or failed test runs, especially when using lateral flow or colorimetric assays.

[0055] According to some embodiments, the strip may include a window or transparent section allowing the user to clearly view the indicator response and / or control . In other embodiments, the indicator may be visible through the device housing or via a dedicated display opening.

[0056] By providing immediate and intuitive feedback, the volume indicator helps bridge the gap between professional diagnostic tools and user-friendly, point-of-care solutions, making the device highly suitable for non-professionals, such as pet owners managing chronic conditions, breeders monitoring fertility cycles, or rural users with limited access to veterinary services. According to some embodiments, the diagnostic strip may be designed with a specialized internal structure that enables precise timing of fluid delivery from a storage cartridge to the sample pad. In particular, the strip is configured so that the flow rate of the diluting or runner solution, i.e., the runner stored in a dedicated cartridge or capsule, matches the expected timing of blood arrival at the absorption area following the incision. This synchronization between the arrival of blood and the arrival of the fluid is essential for achieving optimal sample mixing, capillary movement, and accurate test results.

[0057] According to some embodiments, the architecture of the strip includes engineered flow channels, delay pads, or extended strip length or size that are dimensioned and arranged to introduce a deliberate time lag in the movement of the runner solution. This lag is calibrated to correspond to the typical delay between the moment the incision is made and the time when blood begins to flow and reach the sample pad. As such, the diluting solution (also referred to herein as "a runner") reaches the absorption zone neither too early (which could dilute ambient fluid or air) nor too late (which could allow blood to clot or dry), but rather arrives concurrently or slightly after the blood begins to saturate the sample pad.

[0058] This feature provides a significant advantage over conventional test strips by ensuring precise fluidic coordination, thereby improving test sensitivity, minimizing the required blood volume, and reducing the likelihood of test failure due to premature or delayed reagent contact. The result is a highly controlled, user-independent timing mechanism that enhances the reliability and reproducibility of diagnostic results, particularly in non-lab oratory settings or when operated by non-professional users.

[0059] In some embodiments, the device may incorporate a Silencer, an element designed to significantly diminish operational noise. According to some embodiments, the silencer may be crucial for reducing the sounds produced during the blade’s deployment, thereby minimizing the overall noise level during operation. The Silencer can be made from materials such as silicone, rubber, foam, or composite materials, each selected for its properties of elasticity, density, and environmental resistance. The quiet operation facilitated by the Silencer ensures that the animal remains calm and manageable, which is particularly important to prevent resistance in future procedures.

[0060] Additionally, according to some embodiments, the device may feature a Capsule positioned in the path of the blade. This capsule, upon being cut by the blade, may release one or more medicinal agents directly onto the incision site. These agents can include pain relievers, local anesthesia, coagulants, and antiseptics, each serving to enhance comfort, safety, and the healing process. The immediate release of these chemicals ensures effective application and dosage precision, which is essential for both the immediate and post-procedure phases.

[0061] Moreover, some embodiments introduce a Heating Element designed to warm the ear prior to or during the incision process. This element can operate through mechanisms such as electric resistance heating or chemical activation, providing a soothing warmth that potentially reduces the sensation of pain and improves blood flow. Positioned to target the area most beneficially, this feature makes the blood drawing process less traumatic and more humane, which is especially advantageous in veterinary settings.

[0062] According to some embodiments, the synergistic effect of combining these various components — each with its own unique benefit — may result in a device that is not only highly functional but also significantly improves the humane aspects of veterinary procedures. When these components are integrated into a single device, they work in concert to ensure a procedure that is precise, safe, hygienic, and comfortable for the animal, thereby enhancing the device’s utility in clinical and veterinary settings.

[0063] According to some embodiments, there is provided herein a method for drawing blood from an ear of an animal comprising using the device of the present invention by:

[0064] Securing the device to the animal’s ear using at least one fastening mechanism to ensure stability and precise placement;

[0065] Optionally, adjusting the blade depth using an adjustment mechanism to accommodate the thickness of the animal's ear and to control the depth of the incision;

[0066] Activating the blade within a rotating housing to make a clean and controlled incision in the ear; and

[0067] Collecting the blood from the incision using an absorbent pad positioned directly beneath the blade, ensuring efficient and hygienic collection.

[0068] According to some embodiments, the method may further include the step of operating a heating element to warm the ear prior to or during the incision process.

[0069] According to some embodiments, the present invention provides a device for drawing blood from the ear of an animal in a minimally invasive and user-friendly manner. The device is particularly suitable for animal owners and veterinary personnel aiming to conduct on-site testing without the need for complex tools or procedures. According to some embodiments, the device may include a rotating housing that contains a blade configured to make an incision in the ear, at least one fastening mechanism to secure the device to the animal’s ear, and an absorbent pad for collecting blood from the incision. According to some embodiments, the absorbent pad may be attached to or integrated with a diagnostic strip.

[0070] According to some embodiments, the blade housed within the device may be adjustable, allowing the user to control the depth of the incision based on the size and thickness of the animal’s ear. This is especially useful for animals with delicate or variable ear tissue. The adjustment mechanism ensures that the blade does not penetrate too deeply, minimizing pain, reducing bleeding time, and preventing injury.

[0071] In some embodiments, four depths of penetration may be used: 1.0 mm, 1.5 mm, 2.0 mm, and 2.5 mm, corresponding to different device variants. According to some demonstrative embodiments, a depth of 1.5 mm [AA note - please explain 1.5 mm from where, the exact measurements] may offer an optimal balance between sufficient blood yield and rapid hemostasis.

[0072] According to some embodiments, the rotating housing of the device may be equipped with a silencer to reduce noise during blade activation. In some cases, a capsule or insert made of silicone, rubber, foam, or a composite material may be used to absorb the sound generated by the mechanical movement. This reduction in noise may significantly reduce stress in animals, especially when the device is activated close to the ear.

[0073] According to some embodiments, the device may include a capsule located in the path of the blade. Upon activation, the blade may cut or rupture the capsule, causing one or more medicinal agents to be released onto the incision site. These medicinal agents may include pain relievers, local anesthetics, antiseptics, and coagulants, which together improve the healing process and reduce animal discomfort.

[0074] According to some embodiments, the device may include a cartridge filled with a diluting solution (also referred to as a “runner solution” or "wash fluid"). This runner solution may be used to aid in the transport of the collected blood through a diagnostic strip or lateral flow assay. The solution can help ensure that even small volumes of blood (e.g., 30-60 pL) are effectively drawn into the strip and do not coagulate or stagnate at the collection point.

[0075] In some embodiments, a lever may be provided within the device. When the housing rotates during activation, the lever pushes against the cartridge, releasing the solution at a carefully timed interval — such as 1-10 seconds after incision. The runner solution then flows to a receiving area of the diagnostic strip, where it mixes with the blood and facilitates capillary movement into the absorbent pad and the conjugation pad.

[0076] According to some embodiments, the absorbent pad is detachable and disposable. This feature may enhance hygiene and allows for easy replacement between tests or between animals. The pad may be designed to be attached to the test strip directly or may be a standalone component.

[0077] According to some embodiments, the device may include or be used in conjunction with a diagnostic strip. The strip may feature a sample pad, a receiving zone, and an absorbent pad. A cutting window or area may be included to align with the blade path. Upon activation, the incision delivers blood directly to the sample pad. The runner solution flows through the receiving area to dilute the blood and aid in migration toward the detection zone of the strip.

[0078] This setup allows for small drops of blood to be efficiently dissolved and used in testing, minimizing the cut size needed and contributing to humane use in veterinary contexts.

[0079] According to some embodiments, the fastening mechanism used to attach the device to the animal’s ear may be selected from a group including adjustable straps, magnetic clips, hook-and-loop fasteners (e.g., Velcro), suction-based systems, adhesive pads, slide-locks, and other configurations. In some embodiments, the fastening system is an adjustable clip designed to accommodate different ear shapes, sizes, and sensitivities.

[0080] According to some embodiments, the device may further comprise a heating element configured to warm the ear prior to or during the incision. This can serve to increase blood flow to the ear and reduce discomfort during blood collection.

[0081] According to some embodiments, the actuation of the device may be achieved through a spring-loaded blade mechanism housed within a rotatable or slidable outer housing. In one exemplary embodiment, the blade may be initially held in a retracted position under spring tension. When the user manually rotates or presses a designated activation section, e.g„ such as a trigger or rotating ring on the housing, the movement may disengage a mechanical latch or stop, thereby releasing the stored spring force. The blade is then propelled downward or inward along a predefined linear guide path, causing it to make a controlled, shallow incision in the ear of the animal. Immediately following the cut, the spring or biasing element may retract the blade back into its housing to reduce the risk of injury and exposure.

[0082] According to some embodiments, the rotation or depression of the housing not only actuates the blade but may simultaneously trigger a sequence of additional optional actions, such as:

[0083] Compressing a lever that punctures a capsule or cartridge containing a runner solution (wash buffer);

[0084] Releasing a drug-filled capsule positioned along the blade path;

[0085] Activating a timing mechanism to delay fluid release for optimized sample transport.

[0086] In other embodiments, the actuation may be semi-automated or fully automated. For instance, the blade movement and optional features such as depth adjustment or fluid release may be powered by a small motor, solenoid, or battery-powered actuator. The user may initiate the operation by pressing a button, triggering a short activation sequence that coordinates blade deployment, sample collection, and auxiliary functions. In these embodiments, sensors or microcontrollers may regulate:

[0087] The precise depth of the blade;

[0088] The timing and dosage of medicinal agents or runner solution;

[0089] Safety interlocks to prevent actuation when the device is not correctly positioned. Optionally, an electromechanical depth adjustment may allow the user to preset or select the incision depth via a dial, touchscreen interface, or preset ear size selector. Feedback mechanisms, such as LED indicators or audible tones, may confirm successful positioning and readiness for operation.

[0090] These variations enable the device to be tailored to both manual field applications and automated clinical settings, offering flexibility, safety, and ease of use across a broad spectrum of veterinary or at-home blood sampling scenarios.

[0091] According to some embodiments, the device is specifically designed for safe and reliable operation by non-professional users, such as pet owners or animal caregivers, without the need for veterinary training. The device may incorporate one or more of the following features to support ease of use:

[0092] Single-action activation, reducing the number of steps required to perform the blood draw;

[0093] Pre-calibrated depth settings, removing the need for the user to manually adjust blade penetration; Visual and / or tactile guides for correct placement on the ear;

[0094] Audible or visual feedback (e.g., a click or light) indicating successful activation; Color-coded components to assist with setup, positioning, and disposal;

[0095] Integrated safety lock or child-safety mechanism to prevent accidental activation; Disposable cartridge and pad system, reducing contamination risk and eliminating the need for cleaning.

[0096] These elements collectively ensure that the device is suitable for use in a home environment, providing access to blood-based testing without requiring a trip to a veterinary clinic or lab.

[0097] According to some embodiments, the device and / or components thereof, such as the absorbent pad, cartridge, and blade assembly, may be provided as a sterile single-use kit. In such configurations, the device may be disposed of after one use to prevent crosscontamination and to ensure compliance with biohazard protocols.

[0098] According to some embodiments, the present invention relates to the use of the device for collecting blood from an animal for diagnostic testing. The device is particularly suited for veterinary applications, including both clinical and home-based diagnostic settings, due to its ease of use, controlled incision depth, and integrated sample handling components. The method involves securing the device to the animal’s ear using a suitable fastening mechanism, activating the blade to produce a small but sufficient incision, and collecting the resulting blood via an absorbent pad or diagnostic strip.

[0099] The collected blood may then be used for a variety of diagnostic tests, including but not limited to serological assays, antibody titer evaluations, blood chemistry panels, infection detection, and nutritional assessments. In some embodiments, the device is used in dogs, cats, and other companion animals, and is capable of producing blood volumes suitable for tests that typically require 50 to 150 microliters, such as C-reactive protein (CRP) analysis, hormone level monitoring (e.g., progesterone), or multiparameter rapid tests.

[0100] This use is particularly advantageous for non-professional users, enabling routine health monitoring, pre-vaccination screening, or follow-up testing without requiring venous puncture or access to laboratory settings. The integrated features, e.g., such as blood volume indicators, dilution capsules, and built-in test strips, further streamline the point-of-care testing process, making the device highly suitable for decentralized diagnostics in animal health. Reference is now made to Figure 1, which depicts a cross section view of device 100 of the present invention, according to some demonstrative embodiments.

[0101] Figure 1 illustrates device 100 specifically designed for drawing blood from the ear of an animal, preferably, a dog. The key components of the device and their functions are as follows:

[0102] According to some embodiments, blade 102 may be situated at the bottom of the device and is responsible for making an incision in the ear to facilitate blood collection. According to some embodiments, the blade may be adjustable, allowing its depth to be controlled. In figure 1, this adjustability is depicted with the up and down arrows, and it enables the user to tailor the depth of the cut according to the size and / or thickness of the animal's ear, making device 100 versatile and safe for various breeds.

[0103] According to some embodiments, adjustment mechanism 104 is used to regulate the position of blade 102. By manipulating this mechanism, the user can control the depth of the incision, ensuring precision when drawing blood, depending on the size and shape of the ear being treated.

[0104] According to some embodiments, housing 112 encases and protects the blade and the adjustment mechanism. This housing ensures that the blade is securely positioned, reducing the risk of accidental cuts or exposure to the sharp edge when the device is not in use.

[0105] According to some embodiments, clip 106 is designed to secure the entire device onto the ear of the animal. This ensures stability during the procedure and allows the user to maintain the correct position for an accurate and efficient blood draw. The clip helps to fixate the ear in place, preventing movement that could affect the incision.

[0106] According to some embodiments, absorbent pad 108 is positioned underneath the blade and serves to capture and absorb the blood drawn during the procedure. Pad 108 may ensure that the blood is collected efficiently and prevents unnecessary mess or spillage.

[0107] According to some embodiments, strip 110 may optionally be included in the device for conducting one or more blood analyses. After the blood is drawn and absorbed by the pad, the strip can be used for performing tests or collecting data on the blood sample directly, adding a multifunctional aspect to the device.

[0108] In some embodiments, Automated Blade Adjustment: In an alternative embodiment, the adjustment mechanism 104 may be motorized or semi -automated to allow for even finer control over the blade depth. This feature would enable the user to set a desired depth, and the device would automatically adjust the blade position, reducing the chance of user error.

[0109] According to some embodiments, Detachable Absorbent Pad: The absorbent pad 108 could be designed to be detachable and disposable. In this embodiment, after each blood collection, the pad can be removed and replaced, ensuring hygienic use between different animals or during repeated use on the same animal.

[0110] According to some embodiments, Integrated Blood Collection Chamber: In another embodiment, device 100 may include a small vacuum chamber connected to the pad 108, which would help draw blood more efficiently into the collection area without relying solely on capillary action. This chamber could also be connected to the analysis strip 110, allowing for automatic transfer of the blood sample for testing.

[0111] Adjustable Clip Tension: The clip 106 could be designed with adjustable tension settings, allowing the user to apply the right amount of pressure depending on the thickness and sensitivity of the animal's ear. This feature could be especially useful for larger or more sensitive animals, where the level of pressure is crucial for comfort and safety.

[0112] Multi -Function Testing Strip: strip 110 may be enhanced to support multiple types of blood analysis, such as glucose monitoring, red blood cell count, and other critical health metrics. The user of device 100 could choose the type of analysis needed, and the strip would be equipped to handle various tests simultaneously.

[0113] LED Indicator for Depth Adjustment: In yet another embodiment, the device may include an LED indicator light that signals when the blade is properly adjusted for a particular ear size or thickness. This could provide real-time feedback to the user, ensuring optimal cutting depth is achieved before the incision is made.

[0114] These embodiments ensure that the device is adaptable and capable of performing precise, safe, and hygienic blood draws across a variety of scenarios, further increasing its utility in veterinary or clinical settings.

[0115] Reference is now made to figure 2, which is a cross section of device 100, in accordance with some demonstrative embodiments.

[0116] In accordance with some demonstrative embodiments, Figure 2 illustrates the integration of various components within device 100, including the blade 102, housing 112, clip 106, absorbent pad 108, and strip 110 for allowing the extraction of blood from an ear. Figure 2 also presents Silencer 114, designed to enhance the device's operational tranquility. According to some embodiments, Blade 102 creates precise cuts in the animal's ear for blood collection. According to some embodiments, Housing 112 encases the blade and mechanical parts, ensuring safety and structural integrity. As housing 112 rotates and allows blade 102 to create a cut, housing 112 is expected to bump into the the walls of device 100 creating a noise which might scare the animal and / or traumatize the process of blood extraction.

[0117] According to some embodiments, Silencer 114 may be adapted to diminish operational noise significantly. According to some embodiments, Silencer 114 is crucial for dampening sounds produced during the blade's deployment, thereby minimizing the overall noise level during operation.

[0118] According to some embodiments, silencer 114 may be comprised from any suitable material that may absorb the energy and / or noise of housing 112, including for example, one or more materials selected from the group including Silicone, Rubber, Foam, Composite Materials e.g., Combinations of these materials could be employed to enhance the silencer's effectiveness, taking advantage of multiple properties such as elasticity, density, and environmental resistance.

[0119] According to some embodiments, the quieter operation prevents animal distress or trauma, ensuring that the animal remains calm and more manageable during the blood draw. This is particularly important to prevent resistance in future procedures.

[0120] According to some embodiments, the strategic placement of Silencer 114 may be chosen to ensure that device 100 operates as quietly as possible, thus enhancing the functionality of the device by making it more suitable for use in sensitive veterinary applications. This approach not only improves the operational efficiency of the device but also significantly contributes to its humane use in clinical and veterinary settings.

[0121] Reference is now made to figure 3, which depicts a cross-section view of device 100. In accordance with some demonstrative embodiments, Figure 3 illustrates the integration of various components within device 100, including Capsule 116, which is strategically incorporated to enhance the functionality and comfort of the blood-drawing process from the ear of an animal.

[0122] According to some embodiments, capsule 116 is uniquely positioned in the path of the blade within the device. This placement is intentional so that when the blade is activated to make an incision, it simultaneously cuts through Capsule 116. The capsule is designed to contain one or more compounds, which can include pain relievers, local anesthesia, coagulants, antiseptics or other medicaments beneficial during and / or after the blood collection process.

[0123] According to some embodiments, capsule 166 may contain various function and benefits, including for example;

[0124] Immediate Chemical Release: Upon activation of the blade, as it cuts through the capsule, the chemicals are immediately released onto the site of the incision. This ensures that the medicinal agents are applied directly where needed, optimizing their effectiveness.

[0125] Enhanced Comfort and Safety: The inclusion of painkillers or anesthetic compounds directly at the point of incision can significantly reduce discomfort or pain for the animal, making the procedure less stressful. Additionally, coagulants can help control bleeding, promoting quicker wound closure and healing.

[0126] Precision in Application: The direct application of these agents through the capsule ensures that the dosages are precise and localized, avoiding the risks associated with systemic administration.

[0127] Possible Chemicals in Capsule 116 according to some embodiments, may include:

[0128] Painkillers (Analgesics) or Local Anesthetics: To alleviate pain immediately upon making the incision, enhancing the comfort of the animal, like Lidocaine, Bupivacaine and the like.

[0129] Coagulants: To facilitate rapid clotting at the incision site, minimizing bleeding and enhancing the healing process, such as, Ferric Subsulfate, Silver Nitrate and the like.

[0130] Antiseptics or Disinfectant: To reduce the risk of infection post-procedure by disinfecting the wound site immediately, such as Chlorhexidine, Povidone-Iodine Solution and the like.

[0131] Antibiotics to prevent infection such as Neomycin, Polymyxin B, Bacitracin, Mupirocin and the like.

[0132] This approach to incorporating Capsule 116 within device 100 significantly augments the humane aspects of the procedure by reducing pain and stress for the animal, ensuring a quicker recovery, and minimizing the risk of complications. Such an enhancement underscores the device's utility in veterinary settings, making it a preferred option for animal caregivers and veterinary professionals.

[0133] Reference is now made to figure 4, which depicts a side view of device 100 in accordance with some demonstrative embodiments. In accordance with some demonstrative embodiments, figure 4 depicts device 100, showcasing an integrated Heating Element 118 designed to enhance the blood drawing process from the ear of an animal, specifically aiming to provide comfort and pain alleviation during the procedure.

[0134] According to some embodiments, Heating Element 118 is uniquely placed to warm the ear of the animal either prior to or during the incision process. This warming is intended to soothe the area, potentially reducing the sensation of pain associated with the incision, and possibly improving blood flow, making the collection process more efficient.

[0135] According to some embodiments, by warming the ear, heating element 118 helps in dulling pain receptors temporarily, which can make the incision less painful for the animal as well as promoting blood flow.

[0136] In addition, according to some embodiments, the warmth provided by the element can calm the animal, reducing stress and anxiety associated with the procedure.

[0137] According to some embodiments, element 118 can operate through various mechanisms such as electric resistance heating, where electrical current helps generate heat, or via chemical heating pads that are activated upon exposure to air or a specific trigger.

[0138] According to some demonstrative embodiments, the distinctive design of device 100 facilitates the integration of Heating Element 118. This element is preferably positioned behind Clip 108, optionally encased within Housing 120, which secures the element to device 100. These embodiments highlight the strategic placement of Heating Element 118 to warm the ear from the opposite side of the incision site. This arrangement optimizes the application of heat, ensuring that the warming effect is directly targeted at the area most beneficial for alleviating pain and enhancing blood flow without interfering with the incision process.

[0139] This integration of Heating Element 118 into device 100 significantly enhances the device's functionality by providing thermal comfort, which can make the blood drawing process less traumatic and more humane. This feature is particularly advantageous in veterinary settings, where minimizing animal distress is crucial. The thoughtful incorporation of temperature control and safety mechanisms further underscores device's 100 utility, making it an advanced tool for animal healthcare professionals. Reference is now made to figure 5, which is a view of an exemplary strip 110, in accordance with some demonstrative embodiments.

[0140] In accordance with some optional demonstrative embodiments, strip 110 includes an absorbent pad 130. For the sake of clarity, it is emphasized that the term "absorbent pad" may refer to any pad that can absorb liquids, including diluting solution or bodily fluids, e.g., blood, for the purpose of enabling an examination of the bodily fluids.

[0141] According to some embodiments, the absorbent pad may be separate from strip 110, as depicted for example in figure 1, or alternatively be a part of strip 110, as depicted for example in figure 5.

[0142] According to some embodiments, in order for the bodily fluids to reach (e.g., via capillary movement) the absorbent pad 130 of strip 110, it may be useful to allow for the addition of a diluting solution to add more liquid to the bodily fluids, e.g., in the case of small amounts of bodily fluids.

[0143] According to some embodiments, the diluting solution may be referred to herein as "a runner solution".

[0144] As is shown in figure 5, optional strip 110 may include sample pad 126, configured to absorb the bodily fluids, e.g., blood, and cutting area 128 through which the blade of device 100 may pass as an incision is made for the extrusion of blood.

[0145] According to some demonstrative embodiments, for an efficient amount of liquid to be absorbed onto the absorbent pad 130 it may be beneficial to add the runner solution to a portion of strip 110 called receiving part 124.

[0146] According to some embodiments, receiving part 124 is adapted to receive the runner solution and allow it to flow through sample pad 126, collecting the bodily fluids, e.g., blood, until it reaches absorbent pad 130.

[0147] Reference is now made to figure 6, which is a cross section of device 100, in accordance with some demonstrative embodiments.

[0148] In accordance with some optional demonstrative embodiments, Figure 6 illustrates the integration of various components within device 100, including housing 112, strip 110 with its receiving part 124, cartridge 132 and lever 134 for allowing the extraction of blood from an ear.

[0149] According to some embodiments, housing 112 encases the blade and mechanical parts, ensuring safety and structural integrity. As housing 112 rotates and allows the blade to create a cut, housing 112 causes lever 134 to push cartridge 132 until cartridge 132 is punctured, resulting in the runner solution being transferred to receiving part 124 of strip 110.

[0150] According to some optional embodiments, cartridge 132 containing the runner solution may include a dropper-style head, such as a flexible nozzle or soft tip similar to a pipette. In these embodiments, the user or a mechanical feature within the housing may apply light pressure to the capsule body, causing the liquid to be dispensed manually or semi-automatically into the receiving area of the strip. This approach enables more controlled release of the fluid, minimizes accidental spills, and simplifies reloading or replacement of the capsule. The dropper-style configuration also facilitates compatibility with standard diagnostic strips that require a specific liquid-to-blood ratio for proper test results.

[0151] According to some embodiments, the runner fluid flowing throughout strip 110 will dilute the blood sample reaching sample pad 126.

[0152] According to some embodiments, the strategic placement of cartridge 132 may be chosen to ensure that device 100 operates as efficiently as possible, allowing even the smallest drops of blood to be dissolved and tested. This approach not only improves the operational efficiency of the device but also significantly contributes to its humane use in clinical and veterinary settings as its requires a minimal amount of blood to be extruded, thereby allowing minimal incisions to be performed by device 100.

[0153] Examples

[0154] Example 1: Evaluation of Blood Collection Device in Pigs

[0155] A study was conducted to assess the usability, efficacy, and biological impact of the blood collection device of the present invention (referred to herein as AB device), designed to be applied to the ear of a pig for minimally invasive blood sampling.

[0156] Experimental Setup:

[0157] Subjects: 16 female pigs (~70 kg each), divided into four groups (n=4 per group). Device Variants: Four AB device types were tested, each differing by knife penetration depth:

[0158] Type O: 1.0 mm

[0159] Type A: 1.5 mm

[0160] Type B: 2.0 mm

[0161] Type C: 2.5 mm Measured Parameters:

[0162] Volume of blood obtained (pL)

[0163] Time to hemostasis (seconds)

[0164] Animal response (stress, discomfort)

[0165] Efficacy of blood transport in lateral flow test (with and without wash buffer)

[0166] Device Design Features:

[0167] Each AB device includes:

[0168] A depth-adjustable knife to create a shallow incision.

[0169] A sample pad aligned with the cut site.

[0170] A lateral flow diagnostic strip.

[0171] A wash buffer capsule integrated into the housing, designed to:

[0172] Aid fluid flow to the conjugation pad.

[0173] Dampen activation noise (from ~50 dB to ~8 dB).

[0174] The wash buffer (300 pL) is dispensed ~10 seconds post-activation via a 20 mm extended sample pad, enabling optimal interaction with the collected blood.

[0175] Results:

[0176] Device Placement & Tolerance: All devices were well-tolerated. No adverse effects or behavioral signs of discomfort were noted.

[0177] Noise Evaluation: Devices with wash buffer capsule produced significantly less noise upon activation (~8 dB vs. ~50 dB).

[0178] Blood Collection Volumes:

[0179] Type O: 0-1 pL (ineffective, superficial scratch).

[0180] Type A: 33-58 pL (optimal for testing).

[0181] Type B: 70-110 pL.

[0182] Type C: 125-146 pL.

[0183] Hemostasis Time:

[0184] Type A: 20-30 seconds.

[0185] TypeB: 40-55 seconds.

[0186] Type C: 63-90 seconds. Blood volume and time to hemostasis were positively correlated with blade depth.

[0187] Wash Buffer Effects:

[0188] Crucial for blood volumes <60 pL to enable proper migration in the lateral flow strip.

[0189] In high-volume scenarios (Type C), blood occasionally overwhelmed the strip, leading to signal saturation (reddening).

[0190] Timing of wash buffer release was critical to avoid premature dilution or delayed flow.

[0191] Conclusion:

[0192] The Type A device (1.5 mm blade) provided a consistent and sufficient blood sample (-30-60 pL) for downstream lateral flow diagnostic testing with minimal animal discomfort and quick hemostasis. The use of a wash buffer (runner solution), delivered via the integrated capsule, was shown to be essential for optimal test performance, especially at lower blood volumes.

[0193] Results are summarized in table 1 below

[0194]

[0195]

[0196] Table 1: Summary of results

[0197] While this invention has been described in terms of some specific examples, many modifications and variations are possible. It is therefore understood that within the scope of the appended claims, the invention may be realized otherwise than as specifically described.

Claims

What is claimed is:

1. A device for drawing blood from the ear of an animal comprising:a housing containing a blade for making an incision in the ear;at least one fastening mechanism designed to secure the device onto the ear of the animal; andan absorbent pad configured to collect blood from said incision.

2. The device of claim 1, further comprising a blade adjustment mechanism configured to control the depth of the incision, wherein the blade is adjustable to accommodate varying ear sizes or tissue thicknesses without requiring blade replacement.

3. The device of claim 2, wherein said blade adjustment mechanism comprises a threaded dial, sliding track, or ratchet mechanism that allows incremental depth control.

4. The device of claim 1, further comprising a silencer integrated into the rotating housing to reduce noise during operation.

5. The device of claim 4, wherein said silencer is made from a material selected from the group consisting of silicone, rubber, foam, and composite materials.

6. The device of claim 1, further comprising a capsule positioned in the path of said blade, which releases one or more medicinal agents upon being cut by said blade.

7. The device of claim 6, wherein said medicinal agents include at least one of a pain reliever, a local anesthetic, a coagulant and an antiseptic.

8. The device of claim 1, further comprising a cartridge encompassing one or more solutions for diluting said blood drawn from said animal.

9. The device of claim 8, further comprising a lever configured to apply pressure to the cartridge, causing said solution to be released into a diagnostic strip .

10. The device of claim 1, further comprising an analysis strip connected to the absorbent pad for conducting one or more blood analyses directly from the collected blood.

11. The device of claim 1, wherein said fastening mechanism is selected from the group including at least one of adjustable straps, a magnetic fastening system, a clip, a suction-based system, hook and loop fasteners, adhesive pads, custom molded fittings, or a slide lock mechanism.

12. The device of claim 1, wherein said fastening mechanism comprises an adjustable clip configured to accommodate varying thicknesses and sensitivities of animal ears.

13. A method for drawing blood from an ear of an animal, comprising:securing a device to the ear of the animal using at least one fastening mechanism;activating the blade to make a clean and controlled incision in the ear; andcollecting the blood from the incision using an absorbent pad ensuring efficient and hygienic collection.

14. The method for claim 13, further comprising operating a heating element to warm the ear prior to or during the incision process to reduce pain and discomfort and improve blood flow.

15. Use of the device according to claim 1 for collecting blood for diagnostic testing in an animal.

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